Exploring how the integration of indigenous knowledge in the topic of acids and bases influences Grade 10 Physical Science learners’ conceptions, dispositions and sense-making
- Authors: Haimene, Johanna Shetulimba
- Date: 2019
- Subjects: Physical sciences -- Study and teaching -- Namibia , Ethnoscience -- Study and teaching -- Namibia , Science -- Study and teaching -- Namibia , Curriculum planning -- Study and teaching -- Namibia
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/94996 , vital:31105
- Description: The inclusion of indigenous knowledge (IK) in science education is gaining momentum. That is, it is acknowledged that the starting point in learning is what learners already know from their homes or community. This will be consolidated by what these learners will learn in classroom. It is for this reason that the Namibia National Curriculum for Basic Education (NCBE) advocates Learner Centred Education (LCE). The Physical science syllabus also encourages the use of practical activities to enhance the conceptual understanding of the learners. However, the views and beliefs that learners have towards science influence their learning of science. Looking at the same context, various studies carried out have pointed out that the attitude of learners towards the subject influences their performance in that specific subject. It is against this background that this study sought to explore how the integration of indigenous knowledge in lessons on acids and bases influences (or not) learners’ conceptions, dispositions, interest and sense-making. This study used a mixed-method approach whereby both quantitative and qualitative data were gathered. It is underpinned by the interpretive paradigm. Within the interpretive paradigm a case study approach was employed. The study was carried out with the Grade 10B Physical Science learners at Namaela Secondary School (Pseudonym) in the Oshikoto Region. To generate data, a variety of data generation techniques were employed, namely pre-and post-intervention questionnaires, pre-and post-test, observations, learners’ journal reflections and semi-structured interviews. Conceptions, dispositions and sense-making, and Vygotsky’s socio-cultural theory were used as a lens to analyse the data. A deductive-inductive approach was adopted for data analysis. The findings from the study revealed that learners were able to make sense of science concepts when IK is integrated in the lessons. Additionally, the learners’ conceptions and dispositions shifted positively due to the use of the everyday materials. It emerged that learners were able to learn science well when they link their everyday experiences to school science. This study thus recommends that teachers should be encouraged to integrate IK in their lessons. In order for teachers to effectively integrate IK, the curriculum developers should be explicit on how teachers should integrate IK in their lessons. Moreover, teacher-training institutions should include ways of integrating IK when they are training teachers.
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Exploring Intersemiotic Complementarity in three Namibian Physical Science teachers’ classroom practice
- Authors: Nakakuwa, Tomas
- Date: 2019
- Subjects: Semiotics , Communication in science , Communication in education , Physical sciences -- Study and teaching -- Namibia , Science -- Study and teaching -- Namibia , Language and education -- Namibia , Science teachers -- Training of -- Namibia , Visual learning , Verbal learning
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/96812 , vital:31324
- Description: The Namibian Science curriculum promotes learners’ development of self-confidence, self-knowledge and understanding of the world in which they live. The world we live in is increasingly multimodal, necessitating a multiliteracy in learners in order for them to engage meaningfully with knowledge and skills. Furthermore, scientists themselves engage in a range of inscription practices. While verbal language is the primary medium through which scientific knowledge and concepts are constructed, communicated, and learned, visuals can help learners to gain knowledge that they may not receive from verbal explanation alone. The verbal and visual semiotic modes can also function in a complementarity way, and this is significant in contexts where science lessons are for the most part in a second language - as is the case in Namibia where the language of learning and teaching (LoLT) of English is commonly not the learners’ mother tongue. However, no studies were found exploring the nature of verbal-visual intersemiotic complementarity in the practice of Namibian science teachers, or whether it was related to the number of years of science teaching experience. This study thus aimed to explore the dynamics of verbal-visual intersemiotic complementarity in the classroom practice of three Junior Secondary Physical Science teachers, with varying amounts of science teaching experience, in the Oshana region of Namibia. This qualitative case study, on the dynamics of verbal-visual intersemiotic complementarity in science teacher classroom practice follows in the path of earlier studies which employed Systemic Functional Linguistics (SFL) in the analysis of multimodal discourse. This thesis is also informed by Social Constructivism in which the various semiotic modes are recognised as components of the toolkit for mediating learning. The study adopted the interpretive paradigm. Data collection involved lesson observations and semi-structured interviews. Data analysis involved identification and coding of themes and categories inductively. The results reveal that the participant teachers employed the full range of intersemiotic sense relations which literature outlines. It was found that the ideational meanings in the verbal and visual modes of the science teachers’ practice are lexico-semantically related through these intersemiotic sense relations. While some teachers utilised some intersemiotic sense relations more often than others, there were no correspondences evident between the use of verbal-visual intersemiotic complementarity and the number of years of science teaching experience. The results also indicated that different intersemiotic sense relations served different purposes in the science classroom. The verbal-visual intersemiotic complementarity in the participant teachers’ practice tended to focus on: physical material, processes, symbolism or resemblance. This study has significant implications, providing an empirical basis for informing pre-service Physical Science teachers’ training and guiding the in-service training of Physical Science teachers in Namibia. Since its effective use may not be left up to teaching experience, Namibian Physical Science teacher training programmes need to include the use of verbal-visual intersemiotic complementarity in order to equip and empower Physical Science teachers.
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Exploring Lay people’s understanding of substance abuse
- Authors: Ranase, Asanda
- Date: 2019
- Subjects: Substance abuse -- South Africa , Substance abuse -- Social aspects -- South Africa , Psychology -- Qualitative research -- South Africa , Social constructionism -- South Africa , Lay analysis (Psychoanalysis) -- South Africa , Diagnostic and statistical manual of mental disorders , Dependency (Psychology) -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/114881 , vital:34046
- Description: South Africa has been identified as one of the drug centres of the world (UNODC, 2016). Substance abuse has been implicated in violent crimes and accidental deaths, as well as in the increasing the risk of communicable and non-communicable diseases (Harker Burnhams & Parry, 2015; Pasche & Myers, 2012; van Heerden et al., 2009). Even though substance abuse is evidently a challenge facing South Africa, there is currently a paucity of literature exploring how substance abuse is understood, specifically among lay people. Research indicates that there is a clear need for qualitative inquiry on lay people’s understanding of substance abuse (Keatley et al, 2017; Lang & Rosenberg, 2017; Sorsdahl et al., 2012 ). Available South African research in this area centres on trends, attitudes and perceptions of substance abuse (Sorsdahl, Stein, & Myers, 2012). Previous studies indicate that professionals often define substance abuse according to observable indicators, as well as the type of substance used (APA, 2013). Research shows that lay people tend to lean towards moral models of understanding, in contrast to professionals who align with the medical models. Located within social constructionism, this study provides insight into how the understanding of substance abuse is shaped by society (Gergen & Gergen, 1996). This study aims to explore how lay people understand substance abuse and use, and whether this understanding confirms or contradicts that of professionals/DSM. The study made use of an exploratory research design. The sampling procedures used was a combination of purposive and snowball sampling. A total of 50 participants were recruited and twelve focus groups were conducted. The information was analysed using thematic analysis. Six themes emerged: severity of substance abuse; use, abuse and dependence; functionality; loss of control; gateway substance use and experimenting; and mental health literacy. The findings of this study indicate that lay peoples’ understanding of substance abuse centres on the impact that substance use and abuse have on peoples’ lives. Further suggested by the findings is that, lay people often associate poor interpersonal relationships, functionality or lack thereof and loss of control with substance abuse problems. This view is consistent with that of professionals and the DSM5 (APA, 2013). The findings of this research indicate that there are similarities in the views of lay people and those of professionals regarding substance abuse problems.
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Exploring multiple dimensions of identiy development in black South African adolescents
- Authors: Buso, Masimbulele
- Date: 2019
- Subjects: Identity (Psychology) , Adolescent psychology -- South Africa , Identity (Psychology) in adolescence -- South Africa , Teenagers, Black -- Psychology -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/96702 , vital:31310
- Description: South Africa, just like most African countries, is a country rich in social, political and economic history due to colonisation, specifically the apartheid system. The current socio-political and economic climate of the country is said to influence the process of identity development and formation during adolescence. Therefore, the main aim of the study was to explore the various identities that black adolescents are exploring given the context of the country. Additionally, the aim of this research was to explore the methods in which adolescents utilise to develop their identity and the challenges encountered during this process. The study made use of three data collection methods; a Short Reflective exercise, a Nominal Group Technique and Focus Groups. Data was analysed using thematic analysis to generate main themes and sub themes. The main themes discussed in this study revealed that adolescents experiences multiple aspects of their identity, which exist in a complex interwoven system influenced by both external and internal factors. The main challenge was the difficulty in integrating the dominant westernised/individualistic ideology with the collectivistic ideology that adolescents are raised according to. Overall, the study indicated that the majority of the participants had a positive self-concept and a positive outlook with regards to their future. Recommendations emphasise the need for further research that would be based on the South African context to further explore black identity and to gain contextual information that can be used to combat some of the social issues that the South African youth is challenged with.
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Exploring opportunities for integrating indigenous knowledge and practices into animal husbandry in Grade 10 Agricultural Science lessons
- Authors: Siseho, Robert Simwanza
- Date: 2019
- Subjects: Agriculture -- Study and teaching -- Namibia , Ethnoscience -- Study and teaching -- Namibia , Ethnoscience -- Namibia
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/96790 , vital:31320
- Description: The performance of learners in Agricultural Science at secondary schools in the Omaheke region of Namibia is worrisome. For some years performance in the subject has been below the national average, even though the region is known for its agricultural activities. My assumption is that this could be compounded by the fact that even though the Namibian curriculum encourages teachers to integrate local or indigenous knowledge (IK) in their lessons, it is not clear how this should be executed. It is against this background that this study set out to explore opportunities for integrating indigenous animal husbandry knowledge and practices into the animal husbandry section of Namibian Grade 10 Agricultural Science lessons. This was a qualitative case study underpinned by the interpretive paradigm. The study first focused on finding out what practices and knowledge might be integrated into animal husbandry within Grade 10 Agricultural Science. Secondly, it aimed at finding strategies for integrating indigenous knowledge into Grade 10 Agricultural Science. Thirdly, using my experience of co-developing model lessons with two Grade 10 Agricultural Science teachers, it sought to identify what assistance teachers need to integrate IK. The fourth goal was to observe the lessons taught in order to find out how the two teachers mediated the lessons featuring IK. Data were collected using interviews, workshop discussions, observations (videotaped lessons) and reflections. The data were validated through member checking and triangulation via various techniques. I used Vygotsky’s (1978) sociocultural theory and Wenger’s (1998) community of practice as a composite lens to analyse my data. The findings showed that there is indigenous knowledge in animal husbandry of disease prevention and treatment, the feeding of livestock, castration, de-horning and parasite control. Strategies to integrate IK included inviting or visiting parents or farmers, using the learners’ mother tongue and exploiting local resources. It emerged that teachers need help with teaching strategies, the development of worksheets, lesson planning and the use of technology. The mediation of the lessons included use of the chalkboard and a data projector, worksheets, the teacher assisting learners, and learners assisting one another. The study recommends that teachers integrate IK into their lessons to contextualize learning, increase learners’ participation in class and enhance their understanding of science. It also recommends that curriculum developers make it clear how IK should be integrated and assessed. The study further recommends that institutions of higher education should train teachers on how to integrate IK in the curriculum.
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Exploring the meaning of informal social alcohol consumption rituals in performing masculinity amongst male university students
- Authors: Makgale, Obakeng
- Date: 2019
- Subjects: College students -- Alcohol use , Drinking of alcoholic beverages -- South Africa , College students -- Conduct of life -- South Africa , Male college students -- Conduct of life -- South Africa , Masculinity
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/96680 , vital:31308
- Description: Alcohol use amongst university students has received a significant amount of attention in different countries across the world (Dempster, 2011; Kobin, 2013; Maphisa & Young, 2018). The purpose of this study is to explore the meaning of informal social alcohol drinking rituals in performing masculinity amongst male university students. This study used a Social Constructionist approach to gender as theoretical framework. Thus, gender is understood as constructed through social interactions, where a person performs their masculinity before an approving audience (Butler, 2009; Sallee, 2011). This research employed a qualitative research approach. Four participants were selected for in-depth interviews which were analysed using Thematic Network Analysis (Attride-Sterling, 2001). Two global themes emerged from the data set. The first global theme focused on “Men and Alcohol” and concerns the facilitative role that alcohol use and tolerance plays in masculine performance, exploring how masculinities compete for the hegemonic position through excessive alcohol use. The second global theme concerns the “Wolf Pack” and focuses on how peer groups engage in informal social drinking rituals and how these rituals function within the group dynamic. Informal social drinking rituals appear to play a significant role in successful display of hegemonic forms of masculinity in this context, and also play a significant role in expanding one’s social network. However, the consequences associated with this social practice places one in the position of having to maintain participation in heavy drinking in order to feel secure, leaving one vulnerable to negative consequences associated with excessive drinking.
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Exploring visual literacy development through films in senior phase English first additional language
- Authors: Khosa, Michael
- Date: 2019
- Subjects: Visual litearcy , Motion pictures in education -- South Africa , English language -- Study and teaching (Secondary) -- South Africa
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/92672 , vital:30727
- Description: Despite learners’ general poor performance in English First Additional Language (EFAL), research indicates their wide exposure to film viewing which is untapped when teaching visual literacy in EFAL classes (Mnyanda, 2017). This study identified a golden opportunity of introducing film teaching in the senior phase in order to equip learners with the knowledge, skills and values for self-fulfilment, and meaningful participation in society as citizens of a free country. Two teachers’ meaning-making and pedagogical practices of teaching film were explored in a rural Eastern Cape District, South Africa. Qualitative research methodology was used to collect data from lesson observations using a video camera and post-lesson interviews with each teacher. I drew on Vygotsky’s (1978) socio-cultural theory of learning which privileges learners’ social interaction, More Knowledgeable Other and scaffolding in the learning process. Critical Discourse Analysis offered insights on challenging stereotypes available in designing and redesigning texts. It emerged that lack of resources in previously disadvantaged schools and teachers’ missed opportunities to teach film in context were major causes of underperformance. Findings also interestingly revealed that learners could perform better when taught through the film. This study recommends that schools should teach film since it is can improve learners’ results.
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Factors influencing parents’ decisions when choosing a private school
- Authors: Arendse, David
- Date: 2019
- Subjects: School choice -- South Africa -- Case studies , Competition -- South Africa , Private schools -- South Africa , Consumer behavior , VRIO framework (Valuable, Rare, Imitable and Organized) , St. Stithians College
- Language: English
- Type: text , Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/92628 , vital:30738
- Description: Purpose: Consumers make decisions based on multiple factors that influence their decision-making process. These decisions can be influenced by deep personal reflection to the simple impulsive purchase done to fulfil a need or want. This research study explored the relationship between the resource-based view and the factors considered by parents when selecting a school for their child/children. The Valuable, Rare, Imitable and Organized (VRIO) framework as developed by Barney, J. (1991) outlines the framework through which an organisations resources can be assessed in terms of their potential competitive advantage. The research study was interested in understanding how an educational institution can identify and then leverage its resources to create a competitive advantage. Methodology: Each family that has one or more child enrolled at St Stithians College, which is a private school in Gauteng, South Africa, was invited to participate in the study. This represented a potential population size of 1 700 families, however a sample of 334 was used. The educational institution caters to both boys and girls from Grade R to 12 (Matric). Each family was requested to participate in the study as they had already chosen to have at least one child enrolled. A self-administered close-ended questionnaire was used as the instrument for data collection and the questionnaire was broken into two sections. Section A focused on building a profile of the respondent while section B assessed the level of influence the factors had on a parent’s decision. Section B’s questions were structured as Likert-Scale questions requiring a response between 1 and 5, with 5 being the highest influence, and 1 being the lowest. The responses to the questions were then grouped into the factors they spoke to and the average results per factor were assessed via an ANOVA table to test the null hypothesis that parents do not consider factors when choosing a school for their children. Findings: As a paper, this study set out to discover what the competitive advantage was of a private education institution in South Africa. It did so by identifying what the key factors were when parents selected the school of their choice and then analysed these findings against the resources of the given institution. The ANOVA table analysis of the responses identified that parents do consider factors and that the factor that they were most influenced by was convenience factor, represented by location of the institution and the distance to it. While there are multiple private education suppliers in South Africa, no other provider has the location that St Stithians College has, and as such, its location is its competitive advantage. Significant: This research study will expand the existing but limited competitive advantage body of knowledge in the South African education sector. South African educational institutions will be able to develop similar studies which will then assist in identifying their own competitive advantages. This can better enable education providers to entice consumers to their education services.
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Factors influencing survivorship of Portulacaria afra cuttings in restoration of degraded lands
- Authors: Sholto-Douglas, Craig
- Date: 2019
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/92230 , vital:30692
- Description: Heavy over-browsing, over-grazing, and over-trampling has caused the degradation of vast areas of subtropical thicket, including parts of the Greater Addo Elephant National Park (GAENP). Severe degradation has resulted in the loss of vegetation cover and the deterioration of soils and soil functioning. The South African Department of Environmental Affairs (DEA), and specifically the Natural Resource Management Programme (NRM), have invested in restoration initiatives such as the Subtropical Thicket Restoration Programme (STRP), which has aimed to demonstrate the logistical and practical feasibility of restoring these degraded thickets by planting en masse Portulacaria afra (spekboom) cuttings. However, the planted P. afra cuttings often succumb to various abiotic and biotic stresses. This project aimed to identify various factors which may influence the survival of P. afra cuttings, including i) soil properties, ii) water (rainfall, infiltration, run-off, etc.), iii) browsing by mega-herbivores, iv) topographical features such as slope and aspect, or v) plant species or communities. Biodiversity and carbon baselines were carried out at 50 plots within the Main Camp, Darlington and Kabouga sections of the GAENP, providing pre-planting vegetation and soil data. The en masse planting of P. afra occurred following the completion of the baselines. Following a minimum rest period of three months after planting, survivorship counts were carried out at all plots. Infiltration rate had a significant positive relationship with planted P. afra survivorship across all of the sites. Positive trends between increases in litter and root biomass and planted P. afra cuttings survivorship in Kabouga were also evident. Magnesium, water-holding capacity and increasing soil clay percentage were found to have a significant negative relationship with planted P. afra survivorship in Kabouga. Aluminium, magnesium, and boron all had significant positive relationships with planted P. afra cuttings survivorship in Addo Main Camp. No soil variables had any significant relationship with survivorship of planted P. afra cuttings at Darlington. The presence of elephants (Loxidonta africana) had a significant negative relationship with planted P. afra survivorship. Plant communities in more ‘moderately’ degraded states, characterized by the retention of canopy dominant species, woody vegetation cover, limited bareground and higher cover of litter had higher survivorship of planted P. afra cuttings than those in more severely degraded states. The grass Panicum maximum, and forb Atriplex semibaccata were associated with positive relationships with planted P. afra survivorship across all sites. Future research should aim to develop matrices which plot likely survivorship percentages with parameters of measurable variables, such as infiltration, severity of soil capping, browsing densities, chemical indicators, and degradation severity, to identify suitable biophysical planting conditions for P. afra cuttings. Further research should assess whether the presence of elephants, in high densities, can reduce the economic feasibility of the en masse plantings of P. afra cuttings in attempts to restore degraded landscapes.
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Foreground simulations for observations of the global 21-cm signal
- Authors: Klutse, Diana
- Date: 2019
- Subjects: Cosmic background radiation , Astronomy -- Observations , Electromagnetic waves , Radiation, Background
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/76398 , vital:30557
- Description: The sky-averaged (global) spectrum of the redshifted 21-cm line promises to be a direct probe of the Dark Ages, the period before the first luminous sources formed and the Epoch of Reionization during which these sources produced enough ionizing photons to ionize the neutral intergalactic medium. However, observations of this signal are contaminated by both astrophysical foregrounds which are orders of magnitude brighter than the cosmological signal and by non-astrophysical and non-ideal instrumental effects. It is therefore crucial to understand all these data components and their impacts on the cosmological signal, for successful signal extraction. In this view, we investigated the impact that small scale spatial structures of diffuse Galactic foreground has on the foreground spectrum as observed by a global 21-cm observation. We simulated two different sets of observations using a realistic dipole beam model of two synchotron foreground templates that differ from each other in the small scale structure: the original 408 MHz all-sky map by Haslam et al. (1982) and a version where the calibration was improved to remove artifcats and point sources (Remazeilles et al., 2015). We generated simulated foreground spectra and modeled them using a polynomial expansion in frequency. We found that the different foreground templates have a modest impact on the simulated spectra, generate differences up to 2% in the root mean square of residual spectra after the log-polynomial best fit was subtracted out.
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From farm-workers to farm-owners: a case study of the socio-economic impact of a land reform project on Battlesden farm, Alice, Eastern Cape
- Authors: Nyanda, Langaliphumile
- Date: 2019
- Subjects: Battlesden Farm (South Africa) , Farmers -- Social conditions -- South Africa -- Eastern Cape -- Case studies , Agricultural laborers -- Social conditions -- South Africa -- Eastern Cape -- Case studies , Land tenure -- Government policy -- South Africa , Land reform -- South Africa -- Case studies , Rural development -- Sociological aspects -- South Africa -- Eastern Cape , Rural development -- South Africa -- Eastern Cape -- Case studies
- Language: English
- Type: text , Thesis , Masters , MSocSc
- Identifier: http://hdl.handle.net/10962/96484 , vital:31284
- Description: This is an evaluation of a land reform project of a community which was given land in 2001. There were 16 participants who were interviewed to give their perspectives on different areas of the project which, including the functioning of the Communal Property Associations (CPA), the role of strategic partners such as agribusinesses, and the support provided by the state in ensuring the success of the project. The participants were also asked about the general development of the farm since ownership was transferred to the community in 2001. The study revealed disappointing results in the state of the farm, and the lack of development that has taken place. This was evident in the functioning of the CPA, and the high unemployment which was prevalent on the farm. There were elements of dependency which resulted from the mentorship of the agribusiness, as well as a lack of state support in the general operations of the farm.
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From ‘cleanliness is next to Godliness’ to ‘without perfect health, there is nothing’: discourses of healthy lifestyle in the construction of young adult identities in urban South Africa
- Authors: De Jong, Michelle
- Date: 2019
- Subjects: Health , Cleanliness , Social structure -- Health aspects , Health behavior , Social medicine
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/64940 , vital:28638
- Description: This research explores popular constructions of “healthiness” as individual lifestyle choices in the context of contemporary South African consumer culture, and how these constructions relate to formations of subjectivity. This is a qualitative study conducted within a social constructionist, theoretical framework. Data was collected using in-depth, semi structured interviews and are analysed using a Foucauldian inspired version of discourse analysis. A critical stance is taken towards the assumption in these discourses that their version of healthiness is always and unquestionably positive. Special attention is paid to the lifestyle and marketing media discourses appropriated in understandings of personal health through self-management, and of the optimization of health in the pursuit of well-being. The ways in which different discourses of healthiness facilitate the construction of specific identities are considered in order to untangle some of the problems created by the moralism underpinning popular consumer health discourse. How constructions of healthiness and aspirant healthy lifestyles support, and are supported by, the ideologies and practices of neoliberal capitalism are also explored. From this perspective, healthiness as lifestyle consumption choices can be seen as an ideological apparatus that produces the subjects necessary to reproduce the social order (Althusser, 2001), functioning not only positively amongst the social classes with the leisure and economic resources to pursue these options, but also negatively as victim-blaming of those who are excluded. The argument here is not that health is bad or that people should not be bothered with activities aimed at promoting good health, but that in a context where the concept of health is idealised as always positive and beneficial, the potentially harmful consequences of some of the health discourses we make use of may be occluded. This idealisation of health or ‘healthism’ may also function to divert attention away from some of the challenges to health that are not the direct result of personal behaviours and are unlikely to be remedied through individually focussed interventions, for example, inequality and inadequate access to basic resources. Six discourses which were used to construct understandings of health are analysed. These include Happiness, Freedom, Control, Care, Balance and Goodness. The ways in which these discourses played a role in constructing the kinds of subject positions which were made available to participants, and the possible implications this has, are explored in depth.
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Genetic characterisation of a range of geographically distinct Helicoverpa armigera nucleopolyhedrovirus (HearNPV) isolates and evaluation of biological activity against South African populations of the African bollworm, Helicoverpa armigera (Hu bner) (Lepidoptera: Noctuidae)
- Authors: Mtambanengwe, Kudzai Tapiwanashe Esau
- Date: 2019
- Subjects: Helicoverpa armigera -- Biological control -- South Africa , Baculoviruses -- Genetics , Agricultural pests -- Biological control -- South Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/97334 , vital:31426
- Description: The African bollworm, Helicoverpa armigera Hübner (Lepidoptera: Noctuidae) is a pest of economic and agricultural importance globally. It is a polyphagous pest that feeds on a wide range of host plants including economically important crops. The impact it has on agricultural systems makes its control a priority. The most common method of control is using chemical pesticides; however, continuous application of the pesticides has resulted in the development of resistance. The use of biological control has been investigated and established as an effective method of control as a standalone or part of an integrated pest management (IPM) system. The use of the baculovirus Helicoverpa armigera nucleopolyhedrovirus (HearNPV), has shown promise in the control of H. armigera. Commercial formulations based on the virus are available in many global markets. However, the identification of novel HearNPV isolates will aid in the control of H. armigera as well as provide alternative isolates that may have better virulence. Three new HearNPV isolates were purified and identified from three distinct geographical South African locations H. armigera cadavers and named HearNPV-Albany, HearNPV-KZN and HearNPV-Haygrove. The genomes of two of the HearNPV isolates, namely HearNPV-Albany and HearNPV-KZN were genetically characterised and compared to other geographically distinct HearNPV isolates. Virulence studies were performed comparing the new HearNPV isolates against established commercial HearNPV formulations, Helicovir™ and Helicovex® and other geographically distinct isolated HearNPV, HearNPV-G4 and HearNPV-SP1. Two laboratory colonies were established using H. armigera collected from South African fields in the Belmont Valley near Grahamstown labelled as Albany colony and a colony provided from Haygrove Eden farm near George labelled as Haygrove colony. Biological studies were carried out using the Albany H. armigera colony comparing the rate of development, survival and fertility on bell green peppers, cabbage leaves and on artificial diet. From the biological studies, it was recorded that development and survivorship was best on artificial diet. Regular quality control was required for the maintenance of the colony and continuous generations of healthy larvae were eventually established. Diseased cadavers with signs of baculovirus infection were collected after bioprospecting from the Kwa-Zulu Natal Province in South Africa and were labelled KZN isolate; Belmont Valley near Grahamstown and were labelled Albany isolate; and Haygrove Eden farm near George and were labelled Haygrove isolate for the study. A fourth isolate made up of a crude extract of occlusion bodies (OBs) first described by Whitlock was also analysed and labelled Whitlock isolate. Occlusion bodies were extracted, purified and morphologically identified from the KZN, Albany, Haygrove and Whitlock isolates using TEM. Genomic DNA, which was extracted from the purified OBs. Using PCR, the identity of the OBs as HearNPV was confirmed. Genomic analyses were performed on HearNPV-Albany and HearNPV-KZN through genetic characterisation and comparison with other geographically distinct HearNPV genomes to confirm novelty and establish potential genetic relationships between the isolates through evolutionary distances. Full genomic sequencing of the isolated HearNPV and comparison with other geographically distinct HearNPV isolates identified genomic differences that showed that the HearNPV isolates were novel. HearNPV-Albany and HearNPV-KZN were successfully sequenced and identified as novel isolates with unique fragment patterns and unique gene sequences through deletions or insertions when compared to other geographically distinct HearNPV. This raised the potential for differences in biological activity against H. armigera larvae when tested through biological assays. HearNPV-Whit genome assembly had low quality data which resulted in many gaps and failed assembly. The biological activity of HearNPV isolates from Spain, China, South Africa and two commercial formulations were studied against the laboratory established H. armigera South African colony. The LC50 values of the different South African HearNPV isolates were established to be between 7.7 × 101 OBs.ml-1 for the most effective and 3.2 × 102 OBs.ml-1 for the least effective. The Spanish and Chinese HearNPV isolates resulted in LC50 values of 2.0 × 102 OBs.ml-1 and 1.2 × 101 OBs.ml-1 respectively. The commercial formulations resulted in the least virulence observed with an LC50 of 5.84× 102 OBs.ml-1 and 9.0 × 102 OBs.ml-1 for Helicovex® and Helicovir™ respectively. In this study, novel South African HearNPV isolates were isolated and identified. Through characterisation and bioassays against South African H. armigera populations the HearNPV isolates were shown to have different virulence in comparison to geographically distinct isolates. From this research, there is potential for development of new H. armigera biopesticides based on the novel isolates after field trial testing.
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Governing pregnancy in South Africa: political and health debate, policy and procedures
- Authors: Du Plessis, Ulandi
- Date: 2019
- Subjects: South Africa. Department of Health (1994- ) , Maternal health services -- South Africa , Mothers -- Mortality -- South Africa , Prenatal care -- South Africa , African mothers -- Mortality -- South Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/76552 , vital:30600
- Description: South Africa democratised in 1994. However, due to the discriminatory and segregationist character of the preceding regime, vast swathes of the country’s spaces and people entered the democratic period heavily deprived of essential government services. This was the case with health care in general, including maternal health care. There were also little to no national data available on maternal deaths, especially among the black population. One of the first tasks of the new National Department of Health (NDoH) was to target the high maternal mortality rate. The NDoH made maternal deaths notifiable by law and instituted auditing and information gathering systems in the health sector; health infrastructure was expanded exponentially, and maternal health care was made free. Despite this, the last 24 years have seen the maternal mortality escalate. The latest statistics show that between 1200 and 1300 women die in the South African public health sector each year during pregnancy and the puerperium. This puts the current institutional maternal mortality rate (MMR) at around 154/100 000 live births. The international target for ‘developing’ countries was to reduce the MMR rate by three quarters by 2015, which would have meant a reduction to 38/100 000 live births. The aim of this dissertation is to examine how the democratic South African government (influenced heavily by global health thinking) has laboured to reduce that statistic. I analyse, using Foucauldian discourse analysis, all relevant health and maternal health policies, procedural documents and reports produced by and for the NDoH in the last 24 years. I draw on Foucauldian concepts, specifically those related to Foucault’s work on governmentality. In this dissertation I introduce a new perspective towards the maternal health practices implemented in South Africa, practices that have generally remained unquestioned, been perceived as self-evident, and thus often escaping critical analysis. Through an analysis of the intended operation of the public antenatal clinic (within the larger institutional system) I show how ‘development’ has come to operate as a truth regime in South Africa – facilitating the introduction of liberal governmentality (including some advanced liberal practices) into public health service provision.
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Ground thermal regimes in Western Dronning Maud Land, Antarctica in 2016
- Authors: Masebe, Consliah Tebogo
- Date: 2019
- Subjects: Climatic changes -- Antarctica , Frozen ground -- Research -- Antarctica , Frozen ground -- Thermal properties -- Antarctica , Queen Maud Land , Earth temperature -- Antarctica , Soil temperature -- Antarctica -- Measurement
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/95581 , vital:31173
- Description: Research shows that the climate of Antarctica is changing and, it is vital that the change is monitored to understand how it will affect global ecosystems. Since the International Polar Year (IPY) 2007-2008, research in permafrost studies has grown. However, there are still existing gaps that impede complete understanding of Antarctic cold environments and landscape processes. Permafrost has been noted as one of the major controlling factors of the terrestrial ecosystem dynamics in Antarctica. However, the understanding of Antarctic permafrost, when compared to other cryospheric components, is limited, especially its thermal and physical properties, evolution, as well as links to pedogenesis, hydrology, geomorphic dynamics, and responses to global change. This project provided an understanding and insight to over-arching research that evaluates the state and status of permafrost and the active layer in Dronning Maud Land (DML) through examining short-term variations on ground thermal regimes. The main focus is on understanding the influence of synoptic, diurnal and seasonal events on the active layer in 2016. Analysis of available data shows that ground thermal regimes are influenced by variations in air temperature, pressure, wind speed and to some extent, relative humidity. Subsequently, ground thermal regimes also depend on soil physical characteristics including sediment particle size and bulk density. Furthermore, sediment particle size and bulk density have been found to have a great influence on thermal propagation rates as well as active layer depth; the higher the bulk density, the higher the thermal propagation rate and the lower the bulk density, the lower the thermal propagation rate. Conversely, a large proportion of bigger sediment particle size in soil corresponds with a higher thermal propagation rate and a large proportion of smaller sediment particle size in soil corresponds with a lower thermal propagation rate. Also, ground thermal regimes vary according to seasons. Ground temperatures are more variable in summer, while air temperatures are more variable in winter. The variability according to different seasons shows that the active layer responds to seasonal climatic variations. Additionally, the active layer also responds to synoptic and diurnal weather events.
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Hearing silenced voices: a learning-centred approach to sustainable land rehabilitation and natural resource management
- Authors: Wolff, Margaret Gascoyne
- Date: 2019
- Subjects: Watershed management -- South Africa -- Citizen participation , Water-supply -- Management -- Citizen participation , Environmental education -- South Africa
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/94958 , vital:31101
- Description: South Africa is a semi-arid country with dysfunctional water management. The National Water Act encourages integrated water resource management and public participation in contributing to strategies for managing water within delineated areas. Various challenges hamper progress of integrated water resource management and meaningful participation by residents in catchments across the country. One of the challenges is the lack of knowledge about their role in water resource management. By viewing catchments as complex social-ecological systems, this case study investigates how to establish a learning-centred approach to catchment management forum (CMF) formation. The study addressed three sub-questions: What activity systems need to be prioritised for community participation in CMF formation? What existing learning can be identified within the activity systems? What are the sources for expansive social learning in and between the activity systems? The study draws on social learning theory, and on cultural historical activity theory as it offers a methodological approach to identifying a learning-centred approach to learning in a catchment context. Drawing on this theoretical framework, for research question 1, I identified five activity systems that are present in the study area, are partly representative of the people who live in the area, and are linked to land and water governance either through their positions as government employees within the sector, or the NLEIP in ways that influence communities’ lives and livelihoods. To address question 2, I ran learning-centred workshops and interviewed people who lived in the study area. Careful, respectful listening and participants’ use of home language created the safe space in which residents revealed that they know which water resources are important to protect and where breakdowns in communication happen. For question 3, I analysed the data from the workshops and interviews using a cultural historical activity theory framework to identify discursive manifestations of contradictions within and between activity systems which illuminate the potential for expansive social learning. This study recommends developing an understanding of the complex social-ecological context and prioritising co-learning and community participation in a learning-centred approach to catchment management forum formation. For this, there is need to develop in-depth insight into activity systems associated with water governance in local contexts. In this study I identified five of these activity systems, but the study points to a further range of activity systems that need to be considered for a learning-centred approach to be fully established. The study also found that communities are learning via engaging in the rehabilitation work, through engagements in workshops and within the municipal structures. Additionally, the study identified a number of contradictions that can provide sources of learning for taking an expansive learning approach further in CMF formation. Such an approach may provide the space to build bridges of trust between diverse knowledge systems, and has the potential to encourage sustainable co-operation in natural resource management.
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How do urban dwellers identify with features within urban green spaces in the Eastern Cape?
- Authors: Manyani, Amanda
- Date: 2019
- Subjects: Land use, Urban -- South Africa , Greenbelts -- South Africa , City planning -- South Africa
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/95596 , vital:31174
- Description: Public urban green spaces contain natural and artificial features which play crucial roles in supporting urban social-ecological systems, a fact now recognized globally. The various natural and artificial features contained in public urban green spaces are said to be key contributors to the quality of life and well-being of urban dwellers. Nevertheless, this has been largely ignored in urban design in South Africa, especially in the poorer township and Reconstruction Development Program (RDP) areas. At the individual household and community levels within the poorer communities, the provision of green spaces and trees, as well as recreation facilities, is well below world standards, and much less than what is available in the more affluent areas of South African towns. Additionally, most research on the links between nature and human well-being in urban contexts comes from developed world contexts which adopt a westernized view of the relationship. Yet, in many societies of the Global South, including South Africa, worldviews and experiences of nature in green spaces and use of other recreational features takes on different meanings to those of the Global North. To show these differences, a combination of methods was used in this study, different types of green spaces were assessed and evaluated by structured observations so as to record the features present within the spaces. A survey of 360 households was conducted by targeting green space users and households within 100 metres from a green space. Results indicated that, across all the green space types, formal green spaces had a low cover of shrubs, trees and herbs whilst having high lawn cover. Furthermore, vegetation had poor rating across all the green spaces since the vegetation was either overgrown herbs, dense thickets of shrubs and mostly alien trees that were either diseased or forked. Similar to the disparity in the composition and structure of vegetation within the green spaces, there was a wide variability in the composition of recreational features and amenities across the green spaces. The formal green spaces had the most amenities like play equipment, shelter and seating. Informal green spaces and commonages had little or no recreational features available. The attributes of these spaces therefore influenced the reasons for visiting as more than 90 % of the respondents simply used the spaces for transit. With regards to attitudes and preferences towards particular features, they were emerging sense of strong negative feelings towards natural features. Most respondents emphasized the need for green spaces that are well laid out with maintained lawns, recreational facilities and open vegetation. Thus, the current design and available features within the studied urban green spaces do not meet local needs and aspirations and thus do not contribute to better well-being and quality of life as much as they could. Specifically, the various health benefits linked with being in contact with nature in the public green spaces were not evident in this study. The South African specific context in green space use, perception and people’s preferences is thus crucial for urban planning and sustainability.
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I want them to be confident, to build an argument: an exploration of the structure of knowledge and knowers in Political Studies
- Authors: Hlatshwayo, Mlamuli Nkosingphile
- Date: 2019
- Subjects: Political science -- Study and teaching (Higher) -- South Africa , Education, Higher -- Curricula -- South Africa , Rhodes University. Department of Political Studies
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/92392 , vital:30719
- Description: The 2015-2016 student movements in South African higher education sharply critique what was perceived to be the slow pace of institutional transformation and decolonisation in institutions of higher learning (see Badat, 2016; Heleta, 2016b; Mbembe, 2016). One of the academic fields that has come under scrutiny is Political Studies, which has been accused of being un-transformed, irrelevant and not reflecting local, indigenous scholarship in curricula or pedagogy (see for example Matthews, 2018; Mngomezulu & Hadebe, 2018; Tselapedi, 2016). Although this literature critiques neo-colonial predominance of western thought within the field, and the need to re-centre non-Western modes of being, thinking and intellectualising, I argue that this literature actually considers epistemologies without necessarily making a razor sharp critique at the underlying mechanisms and processes of Political Studies knowledge, and the extent to which it can be decolonised and transformed. It is on this gap that I make a contribution to the field.This study is positioned in the field of higher education decolonisation, with a specific focus on exploring knowledge and knower structures in Political Studies. I explore the various ways in which knowledge is valued and legitimated in the field of Political Studies by asking the “how” question – that is, how is knowledge legitimated in Political Studies? This includes a consideration of how the Postgraduate Diploma in International Studies (PDIS) programme, designed to promote and enable an “expert in African International Studies”, legitimates a certain kind of knower in the field. I employ Basil Bernstein’s pedagogic device as a theoretical foundation for exploring 1) what the field of Political Studies knowledge production looks like, 2) how knowledge is recontextualised from the field of production and into the PDIS curriculum, and 3), how that knowledge is legitimated and evaluated through the programnme’s assessment documents, and what they revel as valued and legitimate curriculum knowledge in the field. Karl Maton’s Legitimation Code theory (LCT), specifically Specialisation, is called upon to offer sharp analytical tools for investigating the underlying mechanisms and processes of the knower and knowledge structures that the programme legitimates. It particularly sheds some insight on the kinds of gazes that are valued in the field of Political Studies in general, and in the PDIS programme in particular. The case study for this research is Rhodes University, a historically white university which offered insight and contested history into the kinds of being, knowledges and knowers that were historically legitimated and valued in the institution, as well as the current institutional landscape, and challenges that the institution is grappling with. The data generation included the formally planned curriculum as contained in the programme’s curriculum documents. These included course outlines, seminar critiques, presentations, class participation; class discussions; essay questions and exams/exam portfolio. The data generation also included semi-structured interviews with the lecturers who were regarded as the “recontextualising agents”, who taught in the programme and who offered key insights on some of the curriculum choices regarding selection, pacing, sequencing and evaluation of the curriculum knowledge in the PDIS programme.This study revealed that that the PDIS programmes values and legitimates curriculum knowledge by ensuring that students have a critical understanding of African political economy, war and conflict on the African continent, as well as the challenges of peacekeeping and peace building in new and fragile African states. This was also seen in how the attributes and dispositions of knowers were also valued in how students needed to have social and cultural gazes in order to access the curriculum and to successfully participate as knowers in the field. This suggested that access to both curriculum knowledge and to being a valued knower in the field, could be said to be relatively open and unrestrictive. In this study, I first argue that looking critically at how Political Studies knowledge is recontextualised from the field of production and into the PDIS curriculum can be seen as a decolonising process as it enables us to see the underlying mechanisms and processes of how Political studies knowledge and knowers are valued and legitimated in the field. This offers us an insightful space to see to what extent the fields of production, recontextualisation, as well as reproduction of Political Studies in general, and the PDIS programme in particular, could be said to have a colonising gaze. It also offers insight on how we can go about exploring, transforming and decolonising Political Studies and the PDIS programme. Secondly, exploring the knowledge and knower structures of the PDIS programme can help curriculum designers, lecturers and students identify the knowledge and knower codes of the curriculum, and to critically reflect on their curriculum codes and how to enable epistemological access to students. Furthermore, this study can help lecturers and curriculum designers construct their curriculum in ways that are inclusive, open, and socially just, by being critically aware of the kind of knowledge that they choose to legitimate, and those they choose to disregard in their knowledge recontextualisation and its evaluation. , Unyaka wezi 2015-2016 wombhikisho wabafundi eningizimu afrika zemfundo ephakeme umcwaningi nokungabikhona kakhulu ukuthi kube kancane awuhambi zesikhungo kanye decolonisation ezikhungweni of higher learning (bheka badat, nowezi-2016; Heleta, 2016b; Mbembe, nowezi-2016). Enye yenkambu yezemfundo ephakeme ethe yaba ngaphansi kokuhlolisiswa kabanzi izifundo zezombusazwe, ebhekene nezingqinamba zokungashinsthi, ukungabi lusizo endaweni, ukungabi yisithombe somphakathi, nokukungangeneleli isifundo somdabu kwezemfundo noma i-pedagogy (bheka isibonelo Matthews, 2018; Mngomezulu & Hadebe, 2018; Tselapedi, nowezi-2016). Nakuba lo mbhalo ugxeka ineo-kholoni ikakhulukazi imicabango yasentshonalanga, nokudinga ukubuyekezwa indlela yokucabanga nobuhlakani okungasibo baseNtshonalanga. Ngiyaphikisana nokuthi lo mbhalo ubuyekeza i-epistomology ngempela ngaphandle kokucwaninga kabanzi ukusetsenziswa kobuhlakani nolwazi lwezemfundo yombusazwe, kanye nokwandisa izinguquko noshintsho. Ngizophonsa esivivaneni kulolu gebe olulapho. Lolu cwaningo lusesimeni sokwenza izinguquko kwinkundlazwelo yemfundo ephakeme, ikakhulu ukuhlola ulwazi kanye nezakhiwo ze-knower kwezemfundo yombusazwe. Ngibheka izindlela ezahlukene ngolwazi kanye nokuba semthethweni kwinkundlazwelo yezemfundo zombusazwe ngokubuza umbuzo “kanjani”-ngokuthi, ulwazi lubekwa kanjani ngokomthethwo wezemfundo yombusazwe? Lokhu kubandakanya inkokhelo yombuzo wokuthi kwenzakala kanjani ukuthi ipostgraduate Diploma in International Studies (pdis), yenzelwe ukukhuthaza kanye nokuba wumpetha kwi African International studies”, ukwenza semthethweni eminye yenkundlazwelo yama-knower. Ngisebenzisa ithiyori ya Basil Bernstein ukuhlola 1) Ibukeka kanjani inkundla yokuhkiqiza yezemfundo zezombusazwe, 2) ngolwazi lobuhlakani enkundleni lapho nasesikhathini uhlelo lwezemfundo PDIS yenza umkhiqizo kanye 3), futhi ukwazi ukuthi khona lusemthethweni uhlelo nokuhlola, nokuthi yini abayiveza ukuthi isemthethweni kwizifundo zolwazi. Ithiyori ka Karl matonâ legitimation code theory (lct), ikakhulu Specialisation, yiyona enganikeza kafuphi izinsiza zokuphenya indlela kanye nenqubo ye-knower kanye nolwazi lwesakhiwo esisemthethweni. Iveza kabanzi izindlela zokubheka ezisemqoka nezisematheni kwinkundla yezemfundo zombusazwe kanye nohlelo lwe PDIS ikakhulukazi Indawo lapho ngizoqhuba khona lolu cwaningo iNyuvesi yaseRhodes, ngokomlando iNyuvesi yabamhlophe enikezana ukuqonda nokuncintana komlando kokungena kwezinhlobo, ubuhlakani kanye nama-knower omlando osemthethweni kanye nokhethekile kulesi sikhungo, kanjalo ne-Landscape yesikhungo samanje, kanye nezinselelo lesi sikhungo sikahulumeni esibheke nazo. Idatha equkethwe ifaka izifundo ezihleliwe ngokomthetho njengokuba zitholakala ezifundweni ezihleliwe kumbhalo. Lokhu, kubandakanya isifundo esinye, amasemina abuyekeziwe, izethulo, nokubamba iqhaza ekilasini; izingxoxo zekilasi; imibuzo yendaba kanye nezivivinyo / nokuhlolwa kwezivivinyo. Idatha yesizukulwane iphinde ibandakanye izingxoxo ezihleliwe kanye nabafundisi abathathwa njengabantu abayizingcithabuchopho, abafundisiwe kulo mkhakha kanye naba neso ekukhethweni kwamanye amakharikhulamu abhekelele ukuhlunga, i-pacing, ukulandelela kanye nokuhlolwa kwekharikhulamu kulwazi lohlelo i-PDIS Lolu cwaningo ludalule ukuthi izinhlelo ze-PDIS zikubeka emqoka kanye nokubeka emthethweni ubuhlakani bekhurikhulamu ngokucophelela ukuthi abafundi bakuqonda ukubaluleka okulunzulu ngezomnotho wombusazwe wase Afrika, yimpi nokungqubuzana ezwenikazi lase-Afrika, ukugcina ukuthula kanye nezinkinga ekwakheni uxolo kanye nobuthakathaka / nophukayo kwezwekazi i-Afrika. Lokhu futhi kubonakele ngendlela yokubambisana kanye nokuziqhathulula kwama-knower aabalulekile ekufundiseni abafundi ngokudinga kokuba nezenhlalo kanye nesiko ukuze bakwazi ukuthola ikhurikhulamu kanye nokubamba iqhaza ngempumelelo njengama-knower kule nkundla. Lokhu kuchaze ukuthi ukufinyelela kuhlelo lokufunda kanye nokuba yilunga lama-knower, kungaba ukuba babonisane ngendlela evulelekile kanye nengenamkhawulo. Kulolu cwaningo, ngaqala ngabheka kabanzi ngokubalulekile ukuthi izifundo zezombusazwe ngolwazi lobuhlakani kwinkundlazwelo yokukhiqiza kanye nePDIS kungabonwa njengenguquko eyenza ukuba sikwazi ukubona ezinye izindlela zokusebenza kwezemfundo zombusazwe kanye nokubeka phambili ama-knower. Lokhu kusenza sibone ukubaluleka komkhiqizo wale nkundla, ukubuyekezwa kwezobuhlakani, kanye nomkhiqizo wezemfundo zombusazwe, kanye nohlelo lwe PDIS ikakhulukazi, kungathiwa ingaba nokubanjwa kokubheka. Iphinde isambulele kabanzi ukuthi singahlola, sense izinguquko kanye noshintsho kwezemfundo zombusazwe kanye nohlelo lwe PDIS. Okwesibili, ukuhlola ulwazi kanye nezakhiwo ze-knower ze-PDIS kungasiza abaklami bekhurikhulamu, abafundisi kanye nabafunsi ukukwazi ukuhlonza ulwazi nekhurikhulamu yekhodi ye-knower, kanye nokwazi ukubuyekeza kabanzi amakhodi ekhurikhulami yabo kanye nokwazi ukwenza i-epistemology ukuba abafundi bafinyelele kuyo. Ngaphezu kwalokhu, lolu cwaningo lungasiza abafundisi kanye nabaklamu bekhurikhulamu ukuba bakwazi ukwakha ikhurikhulamu yabo ngendlela ekhethekile, evulelekile, ngokwenhlalo nje, okubalulekile ukuthi uhlobo lophi lolwazi abakhetha lube semthethweni, kanye nalabo abakhetha ukungayilandeli inqubomgomo yolwazi kanye nokuhlola.
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Identification of possible natural compounds as potential inhibitors against Plasmodium M1 alanyl aminopeptidase
- Authors: Soliman, Omar Samir Abdel Ghaffar
- Date: 2019
- Subjects: Plasmodium , Malaria -- Chemotherapy , Plasmodium -- Inhibitors , Drug resistance in microorganisms , Aminopeptidases
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/72284 , vital:30026
- Description: Malaria is a major tropical health problem with a 29% mortality rate among people of all ages; it also affects 35% of the children. Despite the decrease in mortality rate in recent years, malaria still results in around 2000 deaths per day. Malaria is caused by Plasmodium parasites and is transmitted to humans via the bites from infected female Anopheles mosquitoes during blood meals. There are five different Plasmodium species that can cause human malaria, which include Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae, Plasmodium ovale and Plasmodium knowlesi. Among these five species, the most pathogenic ones are Plasmodium falciparum and Plasmodium vivax. Malaria is usually hard to diagnose because the symptoms are not exclusive to malaria and very similar to flu, e.g., fever, muscle pain, and chills, which lead to the misdiagnosis of malaria cases. Malaria is lethal if not treated because it can cause severe complications in the respiratory tract, liver, metabolic acidosis, and hypoglycemia. The malaria parasite life cycle includes two types of hosts, i.e., a human host and female Anopheles mosquito host. Malaria continuously develops resistance to the available drugs, which is one of the major challenges in disease control. This situation confirms the need to develop new drugs that target virulence factors of malaria. The malarial parasite has three main life cycle stages, which include the host liver stage, host blood stage and vector stage. In the blood stage, parasites degrade hemoglobin to amino acids, which is important as these parasites cannot produce their own amino acids. Different proteases are involved in this hemoglobin degradation process. M1 alanyl aminopeptidase is one of these proteases involved at the end of hemoglobin degradation. This study focused on M1 alanyl aminopeptidase as a potential drug target. M1 alanyl aminopeptidase consists of four domains: N-terminal domain, catalytic domain, middle domain and C-terminal domain. The catalytic domain remains conserved among different Plasmodium species. Inhibition of this enzyme might prevent Plasmodium growth as it can’t produce its own amino acids. In this study, sequence analysis was carried out in both human and Plasmodium M1 alanyl aminopeptidase to identify conserved and divergent regions between them. 3D protein models of the M1 alanyl aminopeptidase from Plasmodium species were built and validated. Then the generated models were used for virtual screening against 623 compounds retrieved from the South African Natural Compounds Database (SANCDB, https://sancdb.rubi.ru.ac.za/). Virtual screening was done using blind and targeted docking methods. Docking was used to identify compounds with selective high binding affinity to the active site of the parasite protein. In this study, one SANCDB compound was selected for each protein: SANC00531 was selected against P. falciparum M1 alanyl aminopeptidase, SANC00469 against P. knowlesi, SANC00660 against P. vivax, SANC00144 against P. ovale and SANC00109 against P. malariae. It was found that Plamsodium M1 alanyl aminopeptidase can be used as a potential drug target as it showed selective binding against different inhibitor compounds. This result will be investigated in future work though molecular dynamic analysis to investigate the stability of protein-ligand complexes.
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If you strike a woman: an analysis of how women are represented in political cartoons of South Africa’s Women’s Day, 2009-2017
- Authors: Levin, Bianca
- Date: 2019
- Subjects: Caricatures and cartoons -- South Africa , Women in mass media -- South Africa , Political cartoons -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/92661 , vital:30731
- Description: On 7 August 2017, two days prior to South Africa’s National Women’s Day, video footage of a representative of the State, Mduduzi Manana, beating up a woman went viral. This marred the Women’s Day celebrations of that year, as it became clear to the public that the he was not going to be punished. As important political commentators, cartoonists used Manana’s actions as an opportunity to depict the violence women face, even in a month dedicated to women. In these cartoons, Manana became the face of a patriarchal system, one which has deeply affected the quality of life for women who, to date, cannot claim their Constitutional rights. This thesis is interested in the mini-narratives of such cartoons, ones which offer a view on the status of South African women. Through this qualitative study, a textual analysis in the spirit of Critical Discourse Analysis of seven selected cartoons leads to a discussion of what their representations of women means for gender justice. What this research shows is that the representations that cartoons offer of the position of women in South Africa are complex. These cartoons articulate that South Africa has a long way to go to reach equality and gender justice. In order for gender justice to be realised, the representation of women needs to evolve into one which recognises women’s plight but does not relegate them to the state of victimhood.
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