Callenges facing school management teams in the general education and training band schools
- Authors: Bafundi,Zealous Mapisa
- Date: 2011
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3538 , vital:43625
- Description: Abstract text The study investigated the factors that lead to the high failure rate of grade 12 learners of the two high schools in the Ngqeleni area of Libode Mega District of the Eastern Cape, South Africa. The study was qualitative in nature; therefore interviews were used as the method of collecting data. Seven SMT members, four parents and four learners were, randomly selected from the two schools in the Ngqeleni area of Libode Mega District. The researcher randomly selected the participants then interviewed them. The researcher used a video recoder as an instrument to record the responses from the participants. To analyse data, the researcher transcribed the interview responses and interpreted them. The main findings of the study showed that the high failure rate was caused by the following factors: over-croweded classes, shortage of teaching and learnin~ materials, lack of parental involvement, teachers' low morale, poor learner discipline, teachers experiencing problems in implementing government policies, work-load and as such teaching becoming stressful. The researcher in his study therefore recommends that the Department of Education plans more workshops for schools to capacitate them. There should be provision for more classrooms and incentives for teachers. Key Words: factors, high failure rate, grade 12, Ngqeleni area, Department of Education. , Thesis (MMED) -- Faculty of Educational Sciences, 2011
- Full Text:
- Date Issued: 2011
- Authors: Bafundi,Zealous Mapisa
- Date: 2011
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3538 , vital:43625
- Description: Abstract text The study investigated the factors that lead to the high failure rate of grade 12 learners of the two high schools in the Ngqeleni area of Libode Mega District of the Eastern Cape, South Africa. The study was qualitative in nature; therefore interviews were used as the method of collecting data. Seven SMT members, four parents and four learners were, randomly selected from the two schools in the Ngqeleni area of Libode Mega District. The researcher randomly selected the participants then interviewed them. The researcher used a video recoder as an instrument to record the responses from the participants. To analyse data, the researcher transcribed the interview responses and interpreted them. The main findings of the study showed that the high failure rate was caused by the following factors: over-croweded classes, shortage of teaching and learnin~ materials, lack of parental involvement, teachers' low morale, poor learner discipline, teachers experiencing problems in implementing government policies, work-load and as such teaching becoming stressful. The researcher in his study therefore recommends that the Department of Education plans more workshops for schools to capacitate them. There should be provision for more classrooms and incentives for teachers. Key Words: factors, high failure rate, grade 12, Ngqeleni area, Department of Education. , Thesis (MMED) -- Faculty of Educational Sciences, 2011
- Full Text:
- Date Issued: 2011
Graduate attributes: A comparison between public and private higher education commerce students in South Africa
- Bissig, Abigail https://orcid.org/0000-0001-8316-629X
- Authors: Bissig, Abigail https://orcid.org/0000-0001-8316-629X
- Date: 2020-01
- Subjects: Education, Higher -- South Africa , Private universities and colleges
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10353/19683 , vital:43166
- Description: In order to handle the capacity shortfall of state-funded universities in developing economies, governments with limited public resources often establish systems and regulations that enable private organisations to provide equivalent qualifications. As such, South Africa (SA) has seen a large growth in the number of registered private higher education institutions (HEIs) offering alternatives to students who are seeking higher education qualifications but do not meet public universities admission criteria. The emergence of private HEIs has resulted in a different type of learning environment. These institutions provide smaller classes than their public counterparts and a faculty which often consists of both part-time and full-time retired public HEIs lecturers and industry experts, in an environment that is more practical, and less research focused. Due to the substantial differences between the public and private higher education sector mandate, the educational quality produced by private HEIs is often a contentious subject among academics. Employer perspectives are that most graduates do not have the necessary work-ready skills to successfully integrate into the workforce. While various studies have attempted to define and measure graduate employability, limited research differentiates between public and private HEI graduates, and even fewer studies compare the level of graduate employability between these two sectors. In an attempt to determine whether any statistically significant differences exist between the graduate attributes of public and private higher education commerce students in SA, this study makes use of the Graduate Skills and Attributes Scale (GSAS). The GSAS clusters eight graduate skills and behaviours into the three holistic, overarching attitudinal domains of personal and intellectual development. These eight graduate attributes include interactive skills, problem-solving and decision-making skills, continuous learning orientation, enterprising skills, presenting and applying information skills, goal-directed behaviour, ethical and responsible behaviour, and analytical thinking skills. Using a quantitative approach, questionnaires were distributed to a total of 416 respondents, consisting of 351 public and 65 private higher education commerce students within SA. The sample consisted of students enrolled in their final year of study, through either a public university or registered private HEI situated within SA, completing a Higher Education Qualifications Sub-Framework (HEQSF) accredited NQF 7 Bachelor of Commerce (B.Com) degree through contact mode of study. After the data collection, independent samples t-tests were used to compare the graduate attributes of the two sectors. The study concludes that higher levels of interactive skills and continuous learning orientation were present among students attending private HEIs, while the remaining six graduate attributes indicated no significant differences between the two sectors. The results of this study provide valuable information to HEIs, students, industry and government, as it measures and compares the level of graduate quality produced by public and private HEIs within SA. , Thesis (MCom) -- Faculty of Management and Commerce, 2020
- Full Text:
- Date Issued: 2020-01
- Authors: Bissig, Abigail https://orcid.org/0000-0001-8316-629X
- Date: 2020-01
- Subjects: Education, Higher -- South Africa , Private universities and colleges
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10353/19683 , vital:43166
- Description: In order to handle the capacity shortfall of state-funded universities in developing economies, governments with limited public resources often establish systems and regulations that enable private organisations to provide equivalent qualifications. As such, South Africa (SA) has seen a large growth in the number of registered private higher education institutions (HEIs) offering alternatives to students who are seeking higher education qualifications but do not meet public universities admission criteria. The emergence of private HEIs has resulted in a different type of learning environment. These institutions provide smaller classes than their public counterparts and a faculty which often consists of both part-time and full-time retired public HEIs lecturers and industry experts, in an environment that is more practical, and less research focused. Due to the substantial differences between the public and private higher education sector mandate, the educational quality produced by private HEIs is often a contentious subject among academics. Employer perspectives are that most graduates do not have the necessary work-ready skills to successfully integrate into the workforce. While various studies have attempted to define and measure graduate employability, limited research differentiates between public and private HEI graduates, and even fewer studies compare the level of graduate employability between these two sectors. In an attempt to determine whether any statistically significant differences exist between the graduate attributes of public and private higher education commerce students in SA, this study makes use of the Graduate Skills and Attributes Scale (GSAS). The GSAS clusters eight graduate skills and behaviours into the three holistic, overarching attitudinal domains of personal and intellectual development. These eight graduate attributes include interactive skills, problem-solving and decision-making skills, continuous learning orientation, enterprising skills, presenting and applying information skills, goal-directed behaviour, ethical and responsible behaviour, and analytical thinking skills. Using a quantitative approach, questionnaires were distributed to a total of 416 respondents, consisting of 351 public and 65 private higher education commerce students within SA. The sample consisted of students enrolled in their final year of study, through either a public university or registered private HEI situated within SA, completing a Higher Education Qualifications Sub-Framework (HEQSF) accredited NQF 7 Bachelor of Commerce (B.Com) degree through contact mode of study. After the data collection, independent samples t-tests were used to compare the graduate attributes of the two sectors. The study concludes that higher levels of interactive skills and continuous learning orientation were present among students attending private HEIs, while the remaining six graduate attributes indicated no significant differences between the two sectors. The results of this study provide valuable information to HEIs, students, industry and government, as it measures and compares the level of graduate quality produced by public and private HEIs within SA. , Thesis (MCom) -- Faculty of Management and Commerce, 2020
- Full Text:
- Date Issued: 2020-01
A decision-making model to guide securing blockchain deployments
- Authors: Cronje, Gerhard Roets
- Date: 2021-10-29
- Subjects: Blockchains (Databases) , Bitcoin , Cryptocurrencies , Distributed databases , Computer networks Security measures , Computer networks Security measures Decision making , Ethereum
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188865 , vital:44793
- Description: Satoshi Nakamoto, the pseudo-identity accredit with the paper that sparked the implementation of Bitcoin, is famously quoted as remarking, electronically of course, that “If you don’t believe it or don’t get it, I don’t have time to try and convince you, sorry” (Tsapis, 2019, p. 1). What is noticeable, 12 years after the famed Satoshi paper that initiated Bitcoin (Nakamoto, 2008), is that blockchain at the very least has staying power and potentially wide application. A lesser known figure Marc Kenisberg, founder of Bitcoin Chaser which is one of the many companies formed around the Bitcoin ecosystem, summarised it well saying “…Blockchain is the tech - Bitcoin is merely the first mainstream manifestation of its potential” (Tsapis, 2019, p. 1). With blockchain still trying to reach its potential and still maturing on its way towards a mainstream technology the main question that arises for security professionals is how do I ensure we do it securely? This research seeks to address that question by proposing a decision-making model that can be used by a security professional to guide them through ensuring appropriate security for blockchain deployments. This research is certainly not the first attempt at discussing the security of the blockchain and will not be the last, as the technology around blockchain and distributed ledger technology is still rapidly evolving. What this research does try to achieve is not to delve into extremely specific areas of blockchain security, or get bogged down in technical details, but to provide a reference framework that aims to cover all the major areas to be considered. The approach followed was to review the literature regarding blockchain and to identify the main security areas to be addressed. It then proposes a decision-making model and tests the model against a fictitious but relevant real-world example. It concludes with learnings from this research. The reader can be the judge, but the model aims to be a practical valuable resource to be used by any security professional, to navigate the security aspects logically and understandably when being involved in a blockchain deployment. In contrast to the Satoshi quote, this research tries to convince the reader and assist him/her in understanding the security choices related to every blockchain deployment. , Thesis (MSc) -- Faculty of Science, Computer Science, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Cronje, Gerhard Roets
- Date: 2021-10-29
- Subjects: Blockchains (Databases) , Bitcoin , Cryptocurrencies , Distributed databases , Computer networks Security measures , Computer networks Security measures Decision making , Ethereum
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188865 , vital:44793
- Description: Satoshi Nakamoto, the pseudo-identity accredit with the paper that sparked the implementation of Bitcoin, is famously quoted as remarking, electronically of course, that “If you don’t believe it or don’t get it, I don’t have time to try and convince you, sorry” (Tsapis, 2019, p. 1). What is noticeable, 12 years after the famed Satoshi paper that initiated Bitcoin (Nakamoto, 2008), is that blockchain at the very least has staying power and potentially wide application. A lesser known figure Marc Kenisberg, founder of Bitcoin Chaser which is one of the many companies formed around the Bitcoin ecosystem, summarised it well saying “…Blockchain is the tech - Bitcoin is merely the first mainstream manifestation of its potential” (Tsapis, 2019, p. 1). With blockchain still trying to reach its potential and still maturing on its way towards a mainstream technology the main question that arises for security professionals is how do I ensure we do it securely? This research seeks to address that question by proposing a decision-making model that can be used by a security professional to guide them through ensuring appropriate security for blockchain deployments. This research is certainly not the first attempt at discussing the security of the blockchain and will not be the last, as the technology around blockchain and distributed ledger technology is still rapidly evolving. What this research does try to achieve is not to delve into extremely specific areas of blockchain security, or get bogged down in technical details, but to provide a reference framework that aims to cover all the major areas to be considered. The approach followed was to review the literature regarding blockchain and to identify the main security areas to be addressed. It then proposes a decision-making model and tests the model against a fictitious but relevant real-world example. It concludes with learnings from this research. The reader can be the judge, but the model aims to be a practical valuable resource to be used by any security professional, to navigate the security aspects logically and understandably when being involved in a blockchain deployment. In contrast to the Satoshi quote, this research tries to convince the reader and assist him/her in understanding the security choices related to every blockchain deployment. , Thesis (MSc) -- Faculty of Science, Computer Science, 2021
- Full Text:
- Date Issued: 2021-10-29
Degradation of Paracetamol and other constituents in Perfalgan®: subtitle if needed. If no subtitle follow instructions in manual
- Authors: Curran,Catherine
- Date: 2014
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3165 , vital:43181
- Description: Abstract text. 5.1 Background Paracetamol (acetaminophen) is useful for the treatment of mild to moderate pain as well as being opiate–sparing. In recent years the problem of poor solubility of paracetamol in water has been overcome and an intravenous formulation of paracetamol developed. In South Africa this is marketed by Bristol-Myers Squibb as Perfalgan®. Each 500 mg or 1g ampoule of Perfalgan® is recommended for single use only and is to be discarded once opened (Medicines.org, n.d.). This is most likely due to concerns about degradation of paracetamol or other ingredients in the solution once exposed to air and sterility issues. However in South Africa where this drug is expensive, some centers use one ampoule for multiple cases over the course of 12-24 hours. No obvious clinical adverse effects have been reported. 5.2 Objective of study The aim of this study was to examine the practice of using a single vial of Perfalgan® in divided doses over the course of a day for different patients by way of assessing the stability of Perfalgan® on exposure to air. The study has three components, namely: 1. In vitro assessment of paracetamol levels on exposure to air and stressors over time. 2. In vitro assessment of levels of the excipients, namely mannitol and cysteine on exposure to air and stressors over time. 3. Assessment of the lipid permeability of paracetamol in Perfalgan® on exposure to air and stressors over time. C Curran 2014 Degradation of paracetamol and other constituents in Perfalgan® 8 5.3 Methodology High performance liquid chromatography (HPCL-UV) was used to determine the concentration of paracetamol and the presence of degradation products in samples taken at set time periods following exposure of Perfalgan® to air and stressors. Initial work was done using pure paracetamol to determine optimal measurement conditions prior to analysing Perfalgan®. The concentrations of the additives and their degradation products were measured using nuclear magnetic resonance (1 H NMR). Appreciable changes in these could indicate a safety hazard or decreased bioavailability. Finally ultraviolet spectroscopy was performed to assess samples at a wider spectrum of wavelengths, instead of the single wavelength used in HPLC. This was used to assess for degradation products which absorb at different wavelengths and therefore may be missed if HPLC was used alone. Ultraviolet spectroscopy was also used to test bioavailability of the drug via the octanol:water partition coefficient under stressed and unstressed conditions. 5.4 Results The paracetamol in Perfalgan® did not degrade on exposure to air over 24 hours. Neither did it degrade on exposure to acid, alkali, oxidative or heat stress. The HPLC retention time was constantly between 3.17-3.29 minutes. 1 H NMR revealed no change in the formulation of Perfalgan® except for the conversion of the oxygen scavenger cysteine to cystine. The octanol:water partition coefficient likewise stayed constant and was in agreement with the value of 0.46-0.49 quoted in the literature (International Programme on Chemical Safety, 2008; McNeil Consumer Healthcare, 2010). 5.5 Conclusion The paracetamol in Perfalgan® did not degrade on exposure to air and other stressors over 24 hours. The formulation as Perfalgan® was likewise found to be stable. The drug retained its lipid permeability over this period. , Thesis (MMED) -- Faculty of Health Sciences, 2014
- Full Text:
- Date Issued: 2014
- Authors: Curran,Catherine
- Date: 2014
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3165 , vital:43181
- Description: Abstract text. 5.1 Background Paracetamol (acetaminophen) is useful for the treatment of mild to moderate pain as well as being opiate–sparing. In recent years the problem of poor solubility of paracetamol in water has been overcome and an intravenous formulation of paracetamol developed. In South Africa this is marketed by Bristol-Myers Squibb as Perfalgan®. Each 500 mg or 1g ampoule of Perfalgan® is recommended for single use only and is to be discarded once opened (Medicines.org, n.d.). This is most likely due to concerns about degradation of paracetamol or other ingredients in the solution once exposed to air and sterility issues. However in South Africa where this drug is expensive, some centers use one ampoule for multiple cases over the course of 12-24 hours. No obvious clinical adverse effects have been reported. 5.2 Objective of study The aim of this study was to examine the practice of using a single vial of Perfalgan® in divided doses over the course of a day for different patients by way of assessing the stability of Perfalgan® on exposure to air. The study has three components, namely: 1. In vitro assessment of paracetamol levels on exposure to air and stressors over time. 2. In vitro assessment of levels of the excipients, namely mannitol and cysteine on exposure to air and stressors over time. 3. Assessment of the lipid permeability of paracetamol in Perfalgan® on exposure to air and stressors over time. C Curran 2014 Degradation of paracetamol and other constituents in Perfalgan® 8 5.3 Methodology High performance liquid chromatography (HPCL-UV) was used to determine the concentration of paracetamol and the presence of degradation products in samples taken at set time periods following exposure of Perfalgan® to air and stressors. Initial work was done using pure paracetamol to determine optimal measurement conditions prior to analysing Perfalgan®. The concentrations of the additives and their degradation products were measured using nuclear magnetic resonance (1 H NMR). Appreciable changes in these could indicate a safety hazard or decreased bioavailability. Finally ultraviolet spectroscopy was performed to assess samples at a wider spectrum of wavelengths, instead of the single wavelength used in HPLC. This was used to assess for degradation products which absorb at different wavelengths and therefore may be missed if HPLC was used alone. Ultraviolet spectroscopy was also used to test bioavailability of the drug via the octanol:water partition coefficient under stressed and unstressed conditions. 5.4 Results The paracetamol in Perfalgan® did not degrade on exposure to air over 24 hours. Neither did it degrade on exposure to acid, alkali, oxidative or heat stress. The HPLC retention time was constantly between 3.17-3.29 minutes. 1 H NMR revealed no change in the formulation of Perfalgan® except for the conversion of the oxygen scavenger cysteine to cystine. The octanol:water partition coefficient likewise stayed constant and was in agreement with the value of 0.46-0.49 quoted in the literature (International Programme on Chemical Safety, 2008; McNeil Consumer Healthcare, 2010). 5.5 Conclusion The paracetamol in Perfalgan® did not degrade on exposure to air and other stressors over 24 hours. The formulation as Perfalgan® was likewise found to be stable. The drug retained its lipid permeability over this period. , Thesis (MMED) -- Faculty of Health Sciences, 2014
- Full Text:
- Date Issued: 2014
The synthesis and characterisation of Sn(IV) porphyrin derivatives and their potential application in anti-cancer and antimicrobial photodynamic therapy
- Authors: Dingiswayo, Somila
- Date: 2021-10
- Subjects: Porphyrins , Photochemotherapy , Cancer Photochemotherapy , Active oxygen Physiological effect , Aromaticity (Chemistry) , Tetrapyrroles , Magnetic circular dichroism , Corroles , Chlorins , Photodynamic antimicrobial chemotherapy (PACT)
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188843 , vital:44791
- Description: In photodynamic therapy (PDT), the activation of light-sensitive drugs in tumour cells produces reactive singlet oxygen species, which cause tumour destruction through a cascade of biochemical reactions. Over the years, the wavelength of activation has been shown to be a critical factor in the penetration of light. Hence the properties of photosensitiser dyes in this context shape their ability to treat deep-seated tumours. In this study, the synthesis, structural characterisation and photophysicochemical properties of a series of Sn(IV) porphyrins with meso-methylthiophenyl rings that have been prepared to study their PDT and photodynamic antimicrobial chemotherapy (PACT) activity properties are reported. The series of Sn(IV) complexes is comprised of a porphyrin (1-Sn), a corrole (2-Sn), a chlorin (3-Sn) and an N-confused porphyrin (4-Sn). Herein, the low symmetry Sn(IV) porphyrin derivatives are shown to have excellent singlet oxygen generation capabilities, and lifetimes of the triplet excited states were in the microsecond range. For example, 4-Sn had a singlet oxygen quantum yield (ФΔ) and an excited triplet state lifetime (τT) of 0.88 and 27 μs, respectively. The complexes were studied using UV-visible and magnetic circular dichroism (MCD) spectroscopies. Interestingly, the positive-to-negative sign sequences of the Faraday B0 terms of 2-Sn and 3-Sn reveal that the structural modifications involved break the degeneracy of the MOs derived from the 1eg* LUMO of the porphyrin 1-Sn. In contrast, a conventional negative-to-positive sign sequence is observed for 4-Sn, since the confusion of a pyrrole moiety also results in a large separation of the 1a1u and 1a2u MOs of the porphyrin 1-Sn that are derived from the HOMO of a C16H162−parent hydrocarbon perimeter. The trends in the electronic structures of the Sn(IV) complexes were further investigated through a series of time-dependent density functional theory calculations, so that the suitability of the different types of complex for use in singlet oxygen applications could be further explored. During in vitro photodynamic antimicrobial chemotherapy (PACT) studies, chlorin derivative 3-Sn had the highest activity towards S. aureus and E. coli with log10 reductions of 10.5 and 8.74, respectively. The unusually high activity of 3-Sn against E.coli suggests that the interaction of neutral photosensitisers with gram-negativebacteria is more complex than previously understood. Anti-cancer PDT studies demonstrated that the photosensitisers had negligible dark cytotoxicity. Upon photoirradiation, the Sn(IV) complexes consistently exhibited IC50 values lower than 15 μM against MCF-7 adenocarcinoma cells. An IC50 value of 1.4 μM for 4-Sn after activation at the deep-red region of the spectrum demonstrates that complexes of this type merit further in-depth investigation. The results provide evidence that the low-symmetry Sn(IV) chlorins and N-confused porphyrins merit further in-depth study for use in singlet oxygen applications. , Thesis (MSc) -- Faculty of Science, Chemistry, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Dingiswayo, Somila
- Date: 2021-10
- Subjects: Porphyrins , Photochemotherapy , Cancer Photochemotherapy , Active oxygen Physiological effect , Aromaticity (Chemistry) , Tetrapyrroles , Magnetic circular dichroism , Corroles , Chlorins , Photodynamic antimicrobial chemotherapy (PACT)
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188843 , vital:44791
- Description: In photodynamic therapy (PDT), the activation of light-sensitive drugs in tumour cells produces reactive singlet oxygen species, which cause tumour destruction through a cascade of biochemical reactions. Over the years, the wavelength of activation has been shown to be a critical factor in the penetration of light. Hence the properties of photosensitiser dyes in this context shape their ability to treat deep-seated tumours. In this study, the synthesis, structural characterisation and photophysicochemical properties of a series of Sn(IV) porphyrins with meso-methylthiophenyl rings that have been prepared to study their PDT and photodynamic antimicrobial chemotherapy (PACT) activity properties are reported. The series of Sn(IV) complexes is comprised of a porphyrin (1-Sn), a corrole (2-Sn), a chlorin (3-Sn) and an N-confused porphyrin (4-Sn). Herein, the low symmetry Sn(IV) porphyrin derivatives are shown to have excellent singlet oxygen generation capabilities, and lifetimes of the triplet excited states were in the microsecond range. For example, 4-Sn had a singlet oxygen quantum yield (ФΔ) and an excited triplet state lifetime (τT) of 0.88 and 27 μs, respectively. The complexes were studied using UV-visible and magnetic circular dichroism (MCD) spectroscopies. Interestingly, the positive-to-negative sign sequences of the Faraday B0 terms of 2-Sn and 3-Sn reveal that the structural modifications involved break the degeneracy of the MOs derived from the 1eg* LUMO of the porphyrin 1-Sn. In contrast, a conventional negative-to-positive sign sequence is observed for 4-Sn, since the confusion of a pyrrole moiety also results in a large separation of the 1a1u and 1a2u MOs of the porphyrin 1-Sn that are derived from the HOMO of a C16H162−parent hydrocarbon perimeter. The trends in the electronic structures of the Sn(IV) complexes were further investigated through a series of time-dependent density functional theory calculations, so that the suitability of the different types of complex for use in singlet oxygen applications could be further explored. During in vitro photodynamic antimicrobial chemotherapy (PACT) studies, chlorin derivative 3-Sn had the highest activity towards S. aureus and E. coli with log10 reductions of 10.5 and 8.74, respectively. The unusually high activity of 3-Sn against E.coli suggests that the interaction of neutral photosensitisers with gram-negativebacteria is more complex than previously understood. Anti-cancer PDT studies demonstrated that the photosensitisers had negligible dark cytotoxicity. Upon photoirradiation, the Sn(IV) complexes consistently exhibited IC50 values lower than 15 μM against MCF-7 adenocarcinoma cells. An IC50 value of 1.4 μM for 4-Sn after activation at the deep-red region of the spectrum demonstrates that complexes of this type merit further in-depth investigation. The results provide evidence that the low-symmetry Sn(IV) chlorins and N-confused porphyrins merit further in-depth study for use in singlet oxygen applications. , Thesis (MSc) -- Faculty of Science, Chemistry, 2021
- Full Text:
- Date Issued: 2021-10
Quantifying the ecological and socioeconomic implications of a recovery/collapse of South Africa’s West Coast rock lobster fishery
- Authors: Eggers, Jessica Marguerite
- Date: 2021-10
- Subjects: Jasus lalandii South Africa , Lobster fisheries South Africa , Lobster fisheries Catch effort South Africa , Fishery management South Africa , Small-scale fisheries South Africa , Economics Sociological aspects , Value chain analysis
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188854 , vital:44792
- Description: The West Coast rock lobster (WCRL) Jasus lalandii fishery is South Africa’s third most valuable fishery, but the stock is currently at less than 2% of its pristine biomass. Scientists are warning that if no measures are taken, the WCRL could face commercial extinction. The necessary reductions in the global Total allowable Catch (TAC) seen in past years have had large economic implications for the WCRL value chain, but research into the socio-economic aspects of this fishery is limited. This study, therefore, aims to establish an overview of the economic revenue over the seasons 2016/17 – 2018/19 by exploring changes and trends in the net seasonal income (NSI) for the fishery, sectors within the fishery and different stakeholders. It also investigates the prospects for the sectors and different actors in this fishery over the seasons 2019/2020 - 2030/31 through analysis of the net present value (NPV) under three proposed global TAC management scenarios (global TAC of 640 tonnes, 1084 tonnes and 1280 tonnes). Data concerning costs and incomes as well as dynamics, mechanisms and concerns surrounding the fishery were collected from stakeholders in the different sectors through interviews and surveys. Further, official records from DEFF (catches, actors, vessels and quotas) and projections made by the Marine Resource Assessment (MARAM) team at the University of Cape Town (rates of recovery of the resource and future catches under the different TAC scenarios) were obtained and analysed. Cost and income data were summarised and models characterising the economic flows within the fishery were created. Calculations regarding the NSI and NPV were made using Monte Carlo simulations to account for the uncertainty surrounding many of the input variables. Results show that while the fishery as a whole made economic profits for the three seasons, the decreasing quotas in 2018/19 had a disproportionately negative impact on some of the representative individuals examined within the different sectors. The projections indicate that while each of the sectors as a whole would continue to make profits largely proportional to their allocation under the different TAC scenarios, many vessel owners in the fishery are likely to face economic losses or very marginal gains under the lower quota options, while the NPV for quota holders who outsource the catching of their quota are likely to be proportionally less affected by the changes in global TAC. This dynamic is important to consider for the future of this fishery. If the resource is to recover, and fishing activity is to continue equitably under the decreased quotas that the recovery of the biomass necessitates, the socio-economic context and the dynamics within which the fishers operate must be considered and studied more extensively and socio-economic consequences of a lower global TAC mitigated while improving the ecological status of the resource. , Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Eggers, Jessica Marguerite
- Date: 2021-10
- Subjects: Jasus lalandii South Africa , Lobster fisheries South Africa , Lobster fisheries Catch effort South Africa , Fishery management South Africa , Small-scale fisheries South Africa , Economics Sociological aspects , Value chain analysis
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188854 , vital:44792
- Description: The West Coast rock lobster (WCRL) Jasus lalandii fishery is South Africa’s third most valuable fishery, but the stock is currently at less than 2% of its pristine biomass. Scientists are warning that if no measures are taken, the WCRL could face commercial extinction. The necessary reductions in the global Total allowable Catch (TAC) seen in past years have had large economic implications for the WCRL value chain, but research into the socio-economic aspects of this fishery is limited. This study, therefore, aims to establish an overview of the economic revenue over the seasons 2016/17 – 2018/19 by exploring changes and trends in the net seasonal income (NSI) for the fishery, sectors within the fishery and different stakeholders. It also investigates the prospects for the sectors and different actors in this fishery over the seasons 2019/2020 - 2030/31 through analysis of the net present value (NPV) under three proposed global TAC management scenarios (global TAC of 640 tonnes, 1084 tonnes and 1280 tonnes). Data concerning costs and incomes as well as dynamics, mechanisms and concerns surrounding the fishery were collected from stakeholders in the different sectors through interviews and surveys. Further, official records from DEFF (catches, actors, vessels and quotas) and projections made by the Marine Resource Assessment (MARAM) team at the University of Cape Town (rates of recovery of the resource and future catches under the different TAC scenarios) were obtained and analysed. Cost and income data were summarised and models characterising the economic flows within the fishery were created. Calculations regarding the NSI and NPV were made using Monte Carlo simulations to account for the uncertainty surrounding many of the input variables. Results show that while the fishery as a whole made economic profits for the three seasons, the decreasing quotas in 2018/19 had a disproportionately negative impact on some of the representative individuals examined within the different sectors. The projections indicate that while each of the sectors as a whole would continue to make profits largely proportional to their allocation under the different TAC scenarios, many vessel owners in the fishery are likely to face economic losses or very marginal gains under the lower quota options, while the NPV for quota holders who outsource the catching of their quota are likely to be proportionally less affected by the changes in global TAC. This dynamic is important to consider for the future of this fishery. If the resource is to recover, and fishing activity is to continue equitably under the decreased quotas that the recovery of the biomass necessitates, the socio-economic context and the dynamics within which the fishers operate must be considered and studied more extensively and socio-economic consequences of a lower global TAC mitigated while improving the ecological status of the resource. , Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 2021
- Full Text:
- Date Issued: 2021-10
The Effects of Monaural Beat Technology on Learners' Experiences of Music Performance Anxiety (MPA)
- Authors: Flanagan, Jayson Edward
- Date: 2021-10-29
- Subjects: Performance anxiety Alternative treatment , School music South Africa Makhanda , Music students South Africa Makhanda Examinations , Beats (Acoustics) Psychological aspects , Monaural Beat Technology
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188419 , vital:44752
- Description: Music performance anxiety (MPA) is related to the experience of persisting, distressful, apprehensions about and/or actual impairment of performance skills in a public context, to a degree unwarranted given the individual’s musical aptitude, training and level of preparation (Salmon 1990). This research project set out to investigate learners’ subjective experiences of the effects of monaural beat (MB) vibrational frequencies on their experiences of MPA. The research project was a qualitative study based on a phenomenological research paradigm, which fundamentally aims to explore an experience in its own terms (Smith et al. 2009). The research participants consisted of four subject music pupils at St Andrew’s College and The Diocesan School for Girls and were interviewed through in-depth, semi-structured interviews over two practical examinations. The results suggested that various factors contribute to the experience of music performance anxiety, such as the performers’ perceptions of audience reactions, as well as the context of the performance. Self-esteem and the performer’s fragile sense of self-worth and self-confidence also play an important role in influencing their music performance anxiety. However, listening to monaural beats during a performance has the ability to lower levels of music performance anxiety by eliciting the following effects: an improved sense of confidence within the listeners; a sense of calm; the monaural beats working on a passive awareness level that allows the beat to operate at a sub-conscious level; the ability to focus better on the task at hand as well as benefit the listener in non-musical contexts such as studying; general concentration or ordinary tasks such as gardening or going for a run. The research suggests that listening to monaural beats during a musical performance can benefit the performer by lowering levels of MPA. As a result, the performer will experience an improved sense of confidence, calmness and the ability to focus better on the task at hand. Monaural beats have also shown to be a useful method of dealing with MPA instead of resorting to pharmaceutical drugs or other methods of coping such as playing games for distraction. , Thesis (MMus) -- Faculty of Humanities, Music and Musicology, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Flanagan, Jayson Edward
- Date: 2021-10-29
- Subjects: Performance anxiety Alternative treatment , School music South Africa Makhanda , Music students South Africa Makhanda Examinations , Beats (Acoustics) Psychological aspects , Monaural Beat Technology
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188419 , vital:44752
- Description: Music performance anxiety (MPA) is related to the experience of persisting, distressful, apprehensions about and/or actual impairment of performance skills in a public context, to a degree unwarranted given the individual’s musical aptitude, training and level of preparation (Salmon 1990). This research project set out to investigate learners’ subjective experiences of the effects of monaural beat (MB) vibrational frequencies on their experiences of MPA. The research project was a qualitative study based on a phenomenological research paradigm, which fundamentally aims to explore an experience in its own terms (Smith et al. 2009). The research participants consisted of four subject music pupils at St Andrew’s College and The Diocesan School for Girls and were interviewed through in-depth, semi-structured interviews over two practical examinations. The results suggested that various factors contribute to the experience of music performance anxiety, such as the performers’ perceptions of audience reactions, as well as the context of the performance. Self-esteem and the performer’s fragile sense of self-worth and self-confidence also play an important role in influencing their music performance anxiety. However, listening to monaural beats during a performance has the ability to lower levels of music performance anxiety by eliciting the following effects: an improved sense of confidence within the listeners; a sense of calm; the monaural beats working on a passive awareness level that allows the beat to operate at a sub-conscious level; the ability to focus better on the task at hand as well as benefit the listener in non-musical contexts such as studying; general concentration or ordinary tasks such as gardening or going for a run. The research suggests that listening to monaural beats during a musical performance can benefit the performer by lowering levels of MPA. As a result, the performer will experience an improved sense of confidence, calmness and the ability to focus better on the task at hand. Monaural beats have also shown to be a useful method of dealing with MPA instead of resorting to pharmaceutical drugs or other methods of coping such as playing games for distraction. , Thesis (MMus) -- Faculty of Humanities, Music and Musicology, 2021
- Full Text:
- Date Issued: 2021-10-29
A Facile Effective Method for the Synthesis of Au-Cdse Nanostructures and their Characterisations.
- Authors: Gaxela, Nelisa Ncumisa
- Date: 2016-5
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3238 , vital:43198
- Description: ABSTRACT We report the synthesis of aqueous and organically soluble cadmium selenide (CdSe) nanoparticles (NPs) doped with gold via a facile and effective method. Briefly the synthesis involves the reduction of selenium powder using sodium sulphite to produce sodium selenosulphate which acts as the selenium source, followed by the addition of CdX (X = Cl2, CH3COO, NO3). The nanoparticles were passivated with trisodium citrate, mercaptopropanoic acid (MPA), potassium sodium tartarate (PST) and L-cysteine which rendered them soluble in water and also acted as stabilizing agents, while passivation with hexadecylamine (HDA) made them soluble in organic solvent which also enhanced their stability. The high quality of the as-synthesized nanoparticles was confirmed using absorption and photoluminescence (PL) spectroscopy, Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and high resolution TEM (HRTEM). The systematic study of the effect of mole ratio, temperature, capping agent, growth time, cadmium precursor and ratio of Au on the size, optical and structural properties on the water soluble CdSe nanoparticles were investigated. All the as-synthesised particles, are blue-shifted in relation to the bulk band gap of CdSe. As the Cd: Se mole ratio increases, the intensity of the citrate capped CdSe materials also increases and the particle sizes are in the range of 2.06 – 4.00 nm. When the temperature was increased, the luminescence intensity quenched whereas the particle size increased. As the growth time increased, the intensity increased and then decreased again towards the end of the reaction. When different capping agents were used the particle sizes range from 2.06 – 3.36 nm for citrate, 2.08 – 3.33 nm for MPA, 2.01 – 2.28 nm for L-cysteine and polydispersed for PST. The luminescence intensity decreased in the order citrate > cysteine > PST > MPA when CdCl2 was used as cadmium precursor. When different cadmium precursors were used for L-cysteine, the particle sizes range from 2.06 – 2.31 nm for Cd(CH3COO)2 and 2.00 – 2.37 nm for Cd(NO3)2 while the intensity increased as the reaction time increased, however, still lower than the CdCl2 materials. The effect of Au ratio showed that the intensity of Au-doped cysteine capped-CdSe increased as the Au ratio decreased. The systematic study of the effect of temperature and growth time in the organic soluble CdSe nanoparticles on the size, optical and structural properties was also investigated. All the as-synthesised particles were blue-shifted in relation to the bulk CdSe. As the temperature increased the particle sizes of the undoped materials range between 2.92 – 2.95 nm at 160 °C and 5.35 – 5.39 nm at 200 °C while for the doped materials the particle size range from 2.53 – 2.61 nm at 160 °C, 3.97 nm at 200 °C and 4.20 – 4.72 nm at 240 °C. The intensity of the doped materials increased as the reaction time increased and then decreased again towards the end of the reaction. After ligand exchange the intensity of the as-synthesized doped and undoped-CdSe NPs was very low compare to the parent organically capped doped and un-doped CdSe. It was discovered that without any further purification, the quality of the materials formed by this method is comparable to that of the best CdSe NPs reported in the literature. This method is safe, inexpensive and reproducible. , Thesis (MsC Chemistry) -- Faculty of Natural Sciences, 2019
- Full Text:
- Date Issued: 2016-5
- Authors: Gaxela, Nelisa Ncumisa
- Date: 2016-5
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3238 , vital:43198
- Description: ABSTRACT We report the synthesis of aqueous and organically soluble cadmium selenide (CdSe) nanoparticles (NPs) doped with gold via a facile and effective method. Briefly the synthesis involves the reduction of selenium powder using sodium sulphite to produce sodium selenosulphate which acts as the selenium source, followed by the addition of CdX (X = Cl2, CH3COO, NO3). The nanoparticles were passivated with trisodium citrate, mercaptopropanoic acid (MPA), potassium sodium tartarate (PST) and L-cysteine which rendered them soluble in water and also acted as stabilizing agents, while passivation with hexadecylamine (HDA) made them soluble in organic solvent which also enhanced their stability. The high quality of the as-synthesized nanoparticles was confirmed using absorption and photoluminescence (PL) spectroscopy, Fourier transform infrared spectroscopy (FTIR), transmission electron microscopy (TEM) and high resolution TEM (HRTEM). The systematic study of the effect of mole ratio, temperature, capping agent, growth time, cadmium precursor and ratio of Au on the size, optical and structural properties on the water soluble CdSe nanoparticles were investigated. All the as-synthesised particles, are blue-shifted in relation to the bulk band gap of CdSe. As the Cd: Se mole ratio increases, the intensity of the citrate capped CdSe materials also increases and the particle sizes are in the range of 2.06 – 4.00 nm. When the temperature was increased, the luminescence intensity quenched whereas the particle size increased. As the growth time increased, the intensity increased and then decreased again towards the end of the reaction. When different capping agents were used the particle sizes range from 2.06 – 3.36 nm for citrate, 2.08 – 3.33 nm for MPA, 2.01 – 2.28 nm for L-cysteine and polydispersed for PST. The luminescence intensity decreased in the order citrate > cysteine > PST > MPA when CdCl2 was used as cadmium precursor. When different cadmium precursors were used for L-cysteine, the particle sizes range from 2.06 – 2.31 nm for Cd(CH3COO)2 and 2.00 – 2.37 nm for Cd(NO3)2 while the intensity increased as the reaction time increased, however, still lower than the CdCl2 materials. The effect of Au ratio showed that the intensity of Au-doped cysteine capped-CdSe increased as the Au ratio decreased. The systematic study of the effect of temperature and growth time in the organic soluble CdSe nanoparticles on the size, optical and structural properties was also investigated. All the as-synthesised particles were blue-shifted in relation to the bulk CdSe. As the temperature increased the particle sizes of the undoped materials range between 2.92 – 2.95 nm at 160 °C and 5.35 – 5.39 nm at 200 °C while for the doped materials the particle size range from 2.53 – 2.61 nm at 160 °C, 3.97 nm at 200 °C and 4.20 – 4.72 nm at 240 °C. The intensity of the doped materials increased as the reaction time increased and then decreased again towards the end of the reaction. After ligand exchange the intensity of the as-synthesized doped and undoped-CdSe NPs was very low compare to the parent organically capped doped and un-doped CdSe. It was discovered that without any further purification, the quality of the materials formed by this method is comparable to that of the best CdSe NPs reported in the literature. This method is safe, inexpensive and reproducible. , Thesis (MsC Chemistry) -- Faculty of Natural Sciences, 2019
- Full Text:
- Date Issued: 2016-5
Women’s perceptions, beliefs and lived experiences of postpartum intrauterine contraception at a District Hospital in the Eastern Cape Province of South Africa – a qualitative study
- Authors: Gibson, Dylan
- Date: 2021-00
- Subjects: Postpartum contraception
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/6833 , vital:51015
- Description: Background There is a significant unmet need for family planning in South Africa where long acting reversible contraceptives (LARC), including intrauterine contraceptive devices (IUCD) are underutilised. The situation is no different in the Amathole District in the Eastern Cape where high rates of unintended pregnancies continue to be a problem. The postpartum period presents a unique opportunity for providing effective contraception. It has been established that immediate post-placental insertion of a copper IUCD is a safe, effective method that has the potential to reduce unintended pregnancy rates. A Post placental intrauterine contraceptive device (PPIUCD) refers to an IUCD that is placed into the uterine fundus immediately after delivery of the placenta after caesarean or vaginal delivery. The understanding of women’s perceptions, beliefs and lived experiences of the PPIUCD in this community has the potential to improve uptake of this method. The aim of the study was to fully explore the phenomenon of postpartum intrauterine contraception as a means of family planning at Madwaleni District Hospital in the Amathole District within the Eastern Cape, South Africa. Methods A qualitative, phenomenological study design was used in gathering data through a combination of three focus group discussions and in-depth individual interviews with three different groups of peripartum women. Data was collected from perinatal women at three snapshots in time, namely prior to labour, during the postpartum admission and at 12 weeks postpartum with the aim to fully explore the phenomenon of post-placental IUCD use in the study population. III Results The data was analysed using the framework method and five themes were derived iteratively from the text. These themes included the perceptions of perinatal women towards a PPIUCD, the origins of these perceptions, the reasons why women would or would not choose the method for themselves and lastly, the experiences of those women who chose the method. The findings of this study showed that PPIUCD was a novel method in this community and that misinformation, largely driven by deficiencies in antenatal counselling, led to hesitancy to adopt the method. These deficiencies extended to those women who consented to a PPIUCD insertion at caesarean section who did not fully understand what they had consented to. Despite this, women were open to a more effective, convenient contraceptive and the overall experiences of those women who chose to use a PPIUCD was positive. Conclusions Post-placental IUCD insertion was a relatively new method in the study population. Deficiencies in antenatal contraceptive counselling created uncertainty and scepticism which in turn contributed to low uptake of the method among perinatal women. Despite this, there was a strong desire amongst perinatal women to access effective, convenient family planning and prevent future unwanted pregnancies. The overall experiences of women who did choose the method was positive. This suggested that with the right counselling and support, there would be an increase in uptake of PPIUCD in the population. Recommendations from this study include the need to explore healthcare workers perspectives on this topic, to further explore the lived experience of PPIUCD users over a longer period of time and to explore the effectiveness of various antenatal counselling strategies to equip women to make peripartum contraceptive choices. , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-00
- Authors: Gibson, Dylan
- Date: 2021-00
- Subjects: Postpartum contraception
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/6833 , vital:51015
- Description: Background There is a significant unmet need for family planning in South Africa where long acting reversible contraceptives (LARC), including intrauterine contraceptive devices (IUCD) are underutilised. The situation is no different in the Amathole District in the Eastern Cape where high rates of unintended pregnancies continue to be a problem. The postpartum period presents a unique opportunity for providing effective contraception. It has been established that immediate post-placental insertion of a copper IUCD is a safe, effective method that has the potential to reduce unintended pregnancy rates. A Post placental intrauterine contraceptive device (PPIUCD) refers to an IUCD that is placed into the uterine fundus immediately after delivery of the placenta after caesarean or vaginal delivery. The understanding of women’s perceptions, beliefs and lived experiences of the PPIUCD in this community has the potential to improve uptake of this method. The aim of the study was to fully explore the phenomenon of postpartum intrauterine contraception as a means of family planning at Madwaleni District Hospital in the Amathole District within the Eastern Cape, South Africa. Methods A qualitative, phenomenological study design was used in gathering data through a combination of three focus group discussions and in-depth individual interviews with three different groups of peripartum women. Data was collected from perinatal women at three snapshots in time, namely prior to labour, during the postpartum admission and at 12 weeks postpartum with the aim to fully explore the phenomenon of post-placental IUCD use in the study population. III Results The data was analysed using the framework method and five themes were derived iteratively from the text. These themes included the perceptions of perinatal women towards a PPIUCD, the origins of these perceptions, the reasons why women would or would not choose the method for themselves and lastly, the experiences of those women who chose the method. The findings of this study showed that PPIUCD was a novel method in this community and that misinformation, largely driven by deficiencies in antenatal counselling, led to hesitancy to adopt the method. These deficiencies extended to those women who consented to a PPIUCD insertion at caesarean section who did not fully understand what they had consented to. Despite this, women were open to a more effective, convenient contraceptive and the overall experiences of those women who chose to use a PPIUCD was positive. Conclusions Post-placental IUCD insertion was a relatively new method in the study population. Deficiencies in antenatal contraceptive counselling created uncertainty and scepticism which in turn contributed to low uptake of the method among perinatal women. Despite this, there was a strong desire amongst perinatal women to access effective, convenient family planning and prevent future unwanted pregnancies. The overall experiences of women who did choose the method was positive. This suggested that with the right counselling and support, there would be an increase in uptake of PPIUCD in the population. Recommendations from this study include the need to explore healthcare workers perspectives on this topic, to further explore the lived experience of PPIUCD users over a longer period of time and to explore the effectiveness of various antenatal counselling strategies to equip women to make peripartum contraceptive choices. , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-00
An Investigation on the Clinical Experiences of Newly Qualified Professional Nurses in Hospital Facilities of the Alfred Nzo District Municipality in the Eastern Cape
- Authors: Hloba, Siyathemba Prince
- Date: 2021-00
- Subjects: Nurse practitioners
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7942 , vital:55856
- Description: The study aimed to explore and describe the clinical experiences of newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. The newly qualified professional nurses may face difficulties in the hospital facilities when it comes to the execution of duties. The newly qualified professional nurses are expected to display knowledge, skills and to have a positive effect on patients, the relatives of patients and their colleagues to alleviate diseases. This challenge may create emotional distress if newly qualified professional nurses receive inadequate guidance from the senior staff members of the hospital facility. The objectives of this study were to explore and describe the clinical experiences of newly qualified professional nurses, to explore how the newly qualified professional nurses were affected emotionally by clinical experiences and to explore the support system to enhance the performance of the newly qualified professional nurses. A qualitative, explorative, descriptive and contextual design was used to explore and describe the experiences of the newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. A purposive sampling of newly qualified professional nurses, with less than two years of experience after completing the community service in the clinical practice, was used. The data were collected through face-to-face and semi-structured interviews. The interviews were conducted until the data were saturated. A pilot study was done before the main study to prove the adequacy and suitability of the methods to conduct the main study. The participants‟ interviews and results of the pilot study were incorporated into the interviews and results of the main study. Tesch‟s method of thematic analysis and an independent coder were used to analyse the data and to draw meaning from the content. The study used Guba and Lincoln‟s criteria of measures to ensure trustworthiness, which included credibility, confirmability, dependability and transferability. Ethical standards were maintained throughout the study as the researcher complied with ethical principles, namely, respect for persons, beneficence, justice and autonomy. The key considerations to curb the spread of the Covid-19 pandemic, as stipulated by the World Health Organisation, were followed during the data collection. On data interpretation, three themes were developed with eight subthemes on the first theme, two subthemes on the second theme and three subthemes on the third theme. The research findings revealed that the participants experienced negative attitudes from colleagues and multidisciplinary team members. The shortage of staff and resources made participants feel ineffective in their work environment. Clinical exposure to different units and procedures in various units added value to the development of the participants. The recommendations were made with regards to three divisions. They were the hospital facilities‟ personnel, future nursing research personnel and nursing schools personnel. In hospital facilities, the recommendations included that all novice professional nurses should be made aware of the emotional impact at work. An annual plan for workshops and in-service training should be implemented. Professional counselling is required for the novice professionals who were exposed to Covid-19 isolation units. A need to increase staff coverage in the clinical units was identified as the workload is too big. Management is encouraged to be more sensitive about the newly employed nurses‟ challenges in their facilities and the most experienced nurses are encouraged to mentor and coach the novice nurses. In the future nursing research, recommendations included that more studies need to be conducted in South Africa and the Eastern Cape province to verify the findings of this research. A specific research study that will focus on the supportive needs of nurses in clinical facilities should be done institutionally to provide evidence-based practice. The research culture on the nurses‟ experiences in clinical facilities needs to become a norm. In nursing schools, the recommendations motivated that the nursing students should be exposed to all clinical units before completing the training xiv course. Further studies need to be conducted to evaluate the balance between theory and clinical learning on duly performance. The nursing education institutions should use quality improvement suggestion boxes for students to consider their experiences and opinions about their learning. Key words : clinical experiences, newly qualified professional nurses, Alfred Nzo district municipalities , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-00
- Authors: Hloba, Siyathemba Prince
- Date: 2021-00
- Subjects: Nurse practitioners
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7942 , vital:55856
- Description: The study aimed to explore and describe the clinical experiences of newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. The newly qualified professional nurses may face difficulties in the hospital facilities when it comes to the execution of duties. The newly qualified professional nurses are expected to display knowledge, skills and to have a positive effect on patients, the relatives of patients and their colleagues to alleviate diseases. This challenge may create emotional distress if newly qualified professional nurses receive inadequate guidance from the senior staff members of the hospital facility. The objectives of this study were to explore and describe the clinical experiences of newly qualified professional nurses, to explore how the newly qualified professional nurses were affected emotionally by clinical experiences and to explore the support system to enhance the performance of the newly qualified professional nurses. A qualitative, explorative, descriptive and contextual design was used to explore and describe the experiences of the newly qualified professional nurses in hospital facilities of the Alfred Nzo District Municipality in the Eastern Cape. A purposive sampling of newly qualified professional nurses, with less than two years of experience after completing the community service in the clinical practice, was used. The data were collected through face-to-face and semi-structured interviews. The interviews were conducted until the data were saturated. A pilot study was done before the main study to prove the adequacy and suitability of the methods to conduct the main study. The participants‟ interviews and results of the pilot study were incorporated into the interviews and results of the main study. Tesch‟s method of thematic analysis and an independent coder were used to analyse the data and to draw meaning from the content. The study used Guba and Lincoln‟s criteria of measures to ensure trustworthiness, which included credibility, confirmability, dependability and transferability. Ethical standards were maintained throughout the study as the researcher complied with ethical principles, namely, respect for persons, beneficence, justice and autonomy. The key considerations to curb the spread of the Covid-19 pandemic, as stipulated by the World Health Organisation, were followed during the data collection. On data interpretation, three themes were developed with eight subthemes on the first theme, two subthemes on the second theme and three subthemes on the third theme. The research findings revealed that the participants experienced negative attitudes from colleagues and multidisciplinary team members. The shortage of staff and resources made participants feel ineffective in their work environment. Clinical exposure to different units and procedures in various units added value to the development of the participants. The recommendations were made with regards to three divisions. They were the hospital facilities‟ personnel, future nursing research personnel and nursing schools personnel. In hospital facilities, the recommendations included that all novice professional nurses should be made aware of the emotional impact at work. An annual plan for workshops and in-service training should be implemented. Professional counselling is required for the novice professionals who were exposed to Covid-19 isolation units. A need to increase staff coverage in the clinical units was identified as the workload is too big. Management is encouraged to be more sensitive about the newly employed nurses‟ challenges in their facilities and the most experienced nurses are encouraged to mentor and coach the novice nurses. In the future nursing research, recommendations included that more studies need to be conducted in South Africa and the Eastern Cape province to verify the findings of this research. A specific research study that will focus on the supportive needs of nurses in clinical facilities should be done institutionally to provide evidence-based practice. The research culture on the nurses‟ experiences in clinical facilities needs to become a norm. In nursing schools, the recommendations motivated that the nursing students should be exposed to all clinical units before completing the training xiv course. Further studies need to be conducted to evaluate the balance between theory and clinical learning on duly performance. The nursing education institutions should use quality improvement suggestion boxes for students to consider their experiences and opinions about their learning. Key words : clinical experiences, newly qualified professional nurses, Alfred Nzo district municipalities , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-00
Echogenic liposomes for ultrasound-triggered drug delivery
- Authors: Izuchukwu, Ezekiel Charles
- Date: 2021-10
- Subjects: Liposomes , Drug delivery systems , Colon (Anatomy) Cancer Treatment , Transmission electron microscopy , Fourier transform infrared spectroscopy , Liquid chromatography , Echogenic liposomes , Ultrasound-triggered drug delivery
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188997 , vital:44805
- Description: Colorectal cancer is one of common cancers worldwide. It is the third most diagnosed cancer and the second leading cause of death. The use of 5-fluorouracil (5-FU) alone or in a chemotherapy regime has been the effective treatment of colorectal cancer patients. The efficacy of 5-FU in colorectal cancer treatment is significantly limited by drug resistance, gastrointestinal, and bone marrow toxicity through high-level expression of thymidylate synthase, justifying a need to improve its therapeutic index. Liposomes are colloidal membranes comprising of one or more lipid bilayers enclosing an aqueous core. They have been used to improve the therapeutic index of many anti-cancer drugs by changing drug absorption, elongating biological half-life, reducing metabolism, and reducing toxicity to healthy tissues. Echogenic liposomes are specifically designed to respond to external triggering like ultrasound stimulation by entrapping a gas or an emulsion that can vaporize. A liposome's unique property is that it can entrap both hydrophobic and hydrophilic substances simultaneously in the lipid bilayer and the aqueous core, respectively. These stimuli-responsive liposomes can be triggered externally with ultrasound, to release the chemotherapeutic cargo only at the required site. This research aims to formulate echogenic liposomes encapsulating 5-FU for potential ultrasound triggered release (echogenic). Liposome formulations wereprepared with lipid composition of crude soybean lecithin and cholesterol by thin-filmhydration method and the drug was passively loaded in the formulation. The 5-FU loadedliposomes were evaluated by dynamic light scattering (DLS) for particle size, polydispersityindex, and zeta potential and transmission electron microscopy (TEM) for morphology.Encapsulated liposomal formulations were also evaluated using physicochemical techniquesincluding thermogravimetric analysis (TGA), differential scanning calorimetry (DSC),Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). Theencapsulation efficiency and release kinetics were studied using a validated high-performanceliquid chromatography (HPLC) method. Echogenic properties were explored by entrapping abiocompatible gas (argon) at the same time as the drug (5-FU) using a pressure/freezemethodology. The liposomal formulations were typically spherical with a size of about 150 nmand encapsulation efficiency of 62%. Low-frequency ultrasound (20 kHz) was used to triggerthe drug release from the complete formulation at 10%, 15%, and 20% amplitude and exposuretime of 5 min and 10 min. The rate of drug release from the nano-carrier was a function of theultrasound amplitude and exposure time and reached a maximum of 65% release under theconditions investigated. The cumulative release was investigated, with and without theapplication of ultrasound. It was demonstrated that the application of ultrasound resulted in complete release (99%) after 12 h while this dropped to 70% without ultrasound. These results are encouraging for optimizing ultrasound parameters for triggered and controlled release of the 5-FU, for conditions such as the management of cancer where low-power ultrasound can be applied. , Thesis (MSc) -- Faculty of Science, Chemistry, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Izuchukwu, Ezekiel Charles
- Date: 2021-10
- Subjects: Liposomes , Drug delivery systems , Colon (Anatomy) Cancer Treatment , Transmission electron microscopy , Fourier transform infrared spectroscopy , Liquid chromatography , Echogenic liposomes , Ultrasound-triggered drug delivery
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188997 , vital:44805
- Description: Colorectal cancer is one of common cancers worldwide. It is the third most diagnosed cancer and the second leading cause of death. The use of 5-fluorouracil (5-FU) alone or in a chemotherapy regime has been the effective treatment of colorectal cancer patients. The efficacy of 5-FU in colorectal cancer treatment is significantly limited by drug resistance, gastrointestinal, and bone marrow toxicity through high-level expression of thymidylate synthase, justifying a need to improve its therapeutic index. Liposomes are colloidal membranes comprising of one or more lipid bilayers enclosing an aqueous core. They have been used to improve the therapeutic index of many anti-cancer drugs by changing drug absorption, elongating biological half-life, reducing metabolism, and reducing toxicity to healthy tissues. Echogenic liposomes are specifically designed to respond to external triggering like ultrasound stimulation by entrapping a gas or an emulsion that can vaporize. A liposome's unique property is that it can entrap both hydrophobic and hydrophilic substances simultaneously in the lipid bilayer and the aqueous core, respectively. These stimuli-responsive liposomes can be triggered externally with ultrasound, to release the chemotherapeutic cargo only at the required site. This research aims to formulate echogenic liposomes encapsulating 5-FU for potential ultrasound triggered release (echogenic). Liposome formulations wereprepared with lipid composition of crude soybean lecithin and cholesterol by thin-filmhydration method and the drug was passively loaded in the formulation. The 5-FU loadedliposomes were evaluated by dynamic light scattering (DLS) for particle size, polydispersityindex, and zeta potential and transmission electron microscopy (TEM) for morphology.Encapsulated liposomal formulations were also evaluated using physicochemical techniquesincluding thermogravimetric analysis (TGA), differential scanning calorimetry (DSC),Fourier-transform infrared spectroscopy (FTIR), and X-ray diffraction (XRD). Theencapsulation efficiency and release kinetics were studied using a validated high-performanceliquid chromatography (HPLC) method. Echogenic properties were explored by entrapping abiocompatible gas (argon) at the same time as the drug (5-FU) using a pressure/freezemethodology. The liposomal formulations were typically spherical with a size of about 150 nmand encapsulation efficiency of 62%. Low-frequency ultrasound (20 kHz) was used to triggerthe drug release from the complete formulation at 10%, 15%, and 20% amplitude and exposuretime of 5 min and 10 min. The rate of drug release from the nano-carrier was a function of theultrasound amplitude and exposure time and reached a maximum of 65% release under theconditions investigated. The cumulative release was investigated, with and without theapplication of ultrasound. It was demonstrated that the application of ultrasound resulted in complete release (99%) after 12 h while this dropped to 70% without ultrasound. These results are encouraging for optimizing ultrasound parameters for triggered and controlled release of the 5-FU, for conditions such as the management of cancer where low-power ultrasound can be applied. , Thesis (MSc) -- Faculty of Science, Chemistry, 2021
- Full Text:
- Date Issued: 2021-10
Outcomes of Drug Resistant Tuberculosis in Two Rural District Hospitals, Eastern Cape Province, South Africa
- Authors: Lotz, John-D Knipe
- Date: 2021-02
- Subjects: Medicinal plants
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/6834 , vital:51018
- Description: Tuberculosis (TB) is still rampant in South Africa, and drug resistant tuberculosis (DR-TB) forms a significant part of this burden on both the health care system and economy. A number of interventions have recently been introduced to help curb the growing epidemic of DR-TB, including increasing access to novel and repurposed drugs, decentralisation of care, and a new shorter (9-11 month) treatment regimen recently endorsed by the World Health Organization (WHO). Significantly, this new regimen has now also become injectable-free (also known as an all-oral regimen). However, at the time of implementation in 2017, the shorter regimen was yet to be proven effective in a programmatic setting in South Africa. This is a retrospective cohort study to describe the outcomes in patients on short and long DR-TB treatment regimens, over five years, at two treatment sites in a rural setting in the Eastern Cape province of South Africa. It is the hope that elucidation of factors involved in affecting outcomes in DR-TB may direct future interventions in these two facilities, and the wider DR-TB program in South Africa , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-02
- Authors: Lotz, John-D Knipe
- Date: 2021-02
- Subjects: Medicinal plants
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/6834 , vital:51018
- Description: Tuberculosis (TB) is still rampant in South Africa, and drug resistant tuberculosis (DR-TB) forms a significant part of this burden on both the health care system and economy. A number of interventions have recently been introduced to help curb the growing epidemic of DR-TB, including increasing access to novel and repurposed drugs, decentralisation of care, and a new shorter (9-11 month) treatment regimen recently endorsed by the World Health Organization (WHO). Significantly, this new regimen has now also become injectable-free (also known as an all-oral regimen). However, at the time of implementation in 2017, the shorter regimen was yet to be proven effective in a programmatic setting in South Africa. This is a retrospective cohort study to describe the outcomes in patients on short and long DR-TB treatment regimens, over five years, at two treatment sites in a rural setting in the Eastern Cape province of South Africa. It is the hope that elucidation of factors involved in affecting outcomes in DR-TB may direct future interventions in these two facilities, and the wider DR-TB program in South Africa , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-02
Prevalence and Implications of Telecommunication Counselling
- Authors: Lusiba, Sinazo.
- Date: 2021
- Subjects: Counseling
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7554 , vital:54349
- Description: ABSTRACT The purpose of the present study was to explore prevalence and implications of telecommunication counselling. Available literature suggests that telecommunication counselling may have far-reaching implications in the mental health practice in general, and particularly in psychology. This study was guided by the social information processing theoretical framework. A total number of 26 mental health practitioners aged from 22 to 45 were selected using purposive sampling. In this study questionnaires were distributed to respondents through email, email was also used to collect the research data. Research ethics, such as confidentiality, anonymity, and voluntary participation, were strictly observed. The Statistical Package for Social Sciences version 23 was used to analyse the data. The analysed data are presented in frequency tables and graphs. This study found that there are effectiveness and efficiency factors associated with the use telecommunication counselling. Furthermore, the findings imply that the popularity of this type of counselling has been growing steadily in the past few years, especially in urban areas. Furthermore, despite the increase and growing popularity in the use of telecommunication counselling, the results suggest the presence of ethical dilemmas that confront the practitioners. , Thesis (Masters) -- Faculy of Humanities, Social Sciences and Law, 2021
- Full Text:
- Date Issued: 2021
- Authors: Lusiba, Sinazo.
- Date: 2021
- Subjects: Counseling
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7554 , vital:54349
- Description: ABSTRACT The purpose of the present study was to explore prevalence and implications of telecommunication counselling. Available literature suggests that telecommunication counselling may have far-reaching implications in the mental health practice in general, and particularly in psychology. This study was guided by the social information processing theoretical framework. A total number of 26 mental health practitioners aged from 22 to 45 were selected using purposive sampling. In this study questionnaires were distributed to respondents through email, email was also used to collect the research data. Research ethics, such as confidentiality, anonymity, and voluntary participation, were strictly observed. The Statistical Package for Social Sciences version 23 was used to analyse the data. The analysed data are presented in frequency tables and graphs. This study found that there are effectiveness and efficiency factors associated with the use telecommunication counselling. Furthermore, the findings imply that the popularity of this type of counselling has been growing steadily in the past few years, especially in urban areas. Furthermore, despite the increase and growing popularity in the use of telecommunication counselling, the results suggest the presence of ethical dilemmas that confront the practitioners. , Thesis (Masters) -- Faculy of Humanities, Social Sciences and Law, 2021
- Full Text:
- Date Issued: 2021
Experiences of Homophobia by the Lesbians, Gays, Bisexual, Transgender, Queer, Intersex and Asexual Students in Selected Institutions of Higher Learning in OR Tambo District Municipality, Eastern Cape Province.
- Authors: Luvo , Kasa
- Date: 2021-00
- Subjects: Sex
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7950 , vital:57232
- Description: Sexuality remains one of the most misinterpreted and misunderstood social concepts. The societal norms have had a role to play. The identification and acceptance of heterosexuality as the only sexual practice has created some misconceptions. Furthermore, the role played by religion has a tremendous influence on how people views sexuality. However, the aim of the study is to investigate the experiences of the LGBTQIA society with special reference to students residing in the OR Tambo district municipality. Social Constructionism and Five Faces of Oppression are theories that underpinned this study. Furthermore, the nature of this research is descriptive and explorative and the methodology utilized in this study correlates to the mentioned research design. Therefore, qualitative research method was adopted in this study. A sample of 15 participants was utilized, and Non-probability sampling procedure was used through snowball sampling. An in-depth interview guide was used for data collection and thematic analysis approach was utilized for the analysis. Findings of the study suggests that there is rife homophobia in the IHL; the students subscribing to heteronormativity have been threatening those who were homosexuals and/or aligning with the LGBTQIA community with physical assault. It further found that they showed resilience and consistency when it came to academic performance. This, they attributed to their urge to “prove the naysers wrong” as they have been told that they will never make it in life because of their sexuality. The study recommends that the university should engage external stakeholders on the decriminalization of homosexuality and that the university should protect their students from all sort of harm. , Thesis (Masters) -- Faculty of Humanities, Social Sciences and Law, 2021
- Full Text:
- Date Issued: 2021-00
- Authors: Luvo , Kasa
- Date: 2021-00
- Subjects: Sex
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7950 , vital:57232
- Description: Sexuality remains one of the most misinterpreted and misunderstood social concepts. The societal norms have had a role to play. The identification and acceptance of heterosexuality as the only sexual practice has created some misconceptions. Furthermore, the role played by religion has a tremendous influence on how people views sexuality. However, the aim of the study is to investigate the experiences of the LGBTQIA society with special reference to students residing in the OR Tambo district municipality. Social Constructionism and Five Faces of Oppression are theories that underpinned this study. Furthermore, the nature of this research is descriptive and explorative and the methodology utilized in this study correlates to the mentioned research design. Therefore, qualitative research method was adopted in this study. A sample of 15 participants was utilized, and Non-probability sampling procedure was used through snowball sampling. An in-depth interview guide was used for data collection and thematic analysis approach was utilized for the analysis. Findings of the study suggests that there is rife homophobia in the IHL; the students subscribing to heteronormativity have been threatening those who were homosexuals and/or aligning with the LGBTQIA community with physical assault. It further found that they showed resilience and consistency when it came to academic performance. This, they attributed to their urge to “prove the naysers wrong” as they have been told that they will never make it in life because of their sexuality. The study recommends that the university should engage external stakeholders on the decriminalization of homosexuality and that the university should protect their students from all sort of harm. , Thesis (Masters) -- Faculty of Humanities, Social Sciences and Law, 2021
- Full Text:
- Date Issued: 2021-00
Factors leading to the high failure rate of grade 12 learners in the Ngqeleni area: A case study of two schools in the Ngqeleni area of the Libode mega district, Eastern Cape.
- Authors: Maqokolo, Gideon Zitobile
- Date: 2014
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3444 , vital:43390
- Description: The study investigated the factors that lead to the high failure rate of grade 12 learners of the two high schools in the Ngqeleni area of Libode Mega District of the Eastern Cape, South Africa. The study was qualitative in nature; therefore interviews were used as the method of collecting data. Seven SMT members, four parents and four learners were, randomly selected from the two schools in the Ngqeleni area of Libode Mega District. The researcher randomly selected the participants then interviewed them. The researcher used a video recoder as an instrument to record the responses from the participants. To analyse data, the researcher transcribed the interview responses and interpreted them. The main findings of the study showed that the high failure rate was caused by the following factors: over-croweded classes, shortage of teaching and learnin~ materials, lack of parental involvement, teachers' low morale, poor learner discipline, teachers experiencing problems in implementing government policies, work-load and as such teaching becoming stressful. The researcher in his study therefore recommends that the Department of Education plans more workshops for schools to capacitate them. There should be provision for more classrooms and incentives for teachers. , Thesis (MMED) -- Faculty of Educational Sciences, 2019
- Full Text:
- Date Issued: 2014
- Authors: Maqokolo, Gideon Zitobile
- Date: 2014
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3444 , vital:43390
- Description: The study investigated the factors that lead to the high failure rate of grade 12 learners of the two high schools in the Ngqeleni area of Libode Mega District of the Eastern Cape, South Africa. The study was qualitative in nature; therefore interviews were used as the method of collecting data. Seven SMT members, four parents and four learners were, randomly selected from the two schools in the Ngqeleni area of Libode Mega District. The researcher randomly selected the participants then interviewed them. The researcher used a video recoder as an instrument to record the responses from the participants. To analyse data, the researcher transcribed the interview responses and interpreted them. The main findings of the study showed that the high failure rate was caused by the following factors: over-croweded classes, shortage of teaching and learnin~ materials, lack of parental involvement, teachers' low morale, poor learner discipline, teachers experiencing problems in implementing government policies, work-load and as such teaching becoming stressful. The researcher in his study therefore recommends that the Department of Education plans more workshops for schools to capacitate them. There should be provision for more classrooms and incentives for teachers. , Thesis (MMED) -- Faculty of Educational Sciences, 2019
- Full Text:
- Date Issued: 2014
Towards Reconfiguring the Agricultural Expert System (AES) for Black Small to Medium Farmer Development for Commercialization: A progressively focused policy literature review and social learning dialogue in the Eastern Cape Raymond Mhlaba Local Municipality
- Authors: Maqwelane, Lwanda
- Date: 2021-10
- Subjects: Farms, Small South Africa Amathole District Municipality , Minority farmers , Public-private sector cooperation South Africa Amathole District Municipality , Social learning South Africa Amathole District Municipality , Agricultural expert system (AES) , Black small to medium farmers (BSMF)
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188876 , vital:44794
- Description: This study focuses on the agricultural expert system (AES), its inherited and potential reframing capabilities for the development, growth and transition of black small to medium farmers (BSMF) into the commercial sector. The study was conducted as a critical analytical policy review of implemented policies pre-and post 1994 that subsequently highlighted the thematic continuities and discontinuities of policy reform and the subsequent impact on BSMFs using the AES as a conceptual lens. The study aimed working with stakeholders in the AES in the Raymond Mhlaba Local Municipality as a case study to critically engage and question the AES and its contemporary framing and potential reframing and continued impact on the BSMFs development. This was conducted through a dialogical social learning process in partnership with diverse voices that cut across the contemporary agrarian landscape that included “universities, think tanks, vocational training providers, standards-setting agencies, trade associations that provide specialized training, education, information, research and technical support” (Porter, 2000, p.17). The data for the social learning dialogue process was generated through an iterative analysis of dialogical social learning workshops, focus groups and semi-structured interviews. The analysis focused on the framing (Chapters 2, 3, and 5) and reframing of the AES (Chapter 6). Through dynamic engagement within the knowledge hub (contextual social learning and literature), the study surfaces a potential alternative discourse that actively includes the BSMFs as a crucial component of the commercial sector AES as the analysis shows these are largely excluded. This alternative discourse occurred through dialogical interactions with all participants via a pro-actively constituted social learning process, enriched and deepened by literature as indicated above. Main recommendations of the study are: 1. The AES must be framed to address the holistic value chain of BSMFs to help address underlying policy dualism, 2. Public Private Partnerships are needed to support BSMFs development and these should adopt a social learning approach that is reflective of complex realities 3. There is need for better understanding of roles and contributions of stakeholders in the AES to avoid duplications. , Thesis (MEd) -- Faculty of Education, Education, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Maqwelane, Lwanda
- Date: 2021-10
- Subjects: Farms, Small South Africa Amathole District Municipality , Minority farmers , Public-private sector cooperation South Africa Amathole District Municipality , Social learning South Africa Amathole District Municipality , Agricultural expert system (AES) , Black small to medium farmers (BSMF)
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/10962/188876 , vital:44794
- Description: This study focuses on the agricultural expert system (AES), its inherited and potential reframing capabilities for the development, growth and transition of black small to medium farmers (BSMF) into the commercial sector. The study was conducted as a critical analytical policy review of implemented policies pre-and post 1994 that subsequently highlighted the thematic continuities and discontinuities of policy reform and the subsequent impact on BSMFs using the AES as a conceptual lens. The study aimed working with stakeholders in the AES in the Raymond Mhlaba Local Municipality as a case study to critically engage and question the AES and its contemporary framing and potential reframing and continued impact on the BSMFs development. This was conducted through a dialogical social learning process in partnership with diverse voices that cut across the contemporary agrarian landscape that included “universities, think tanks, vocational training providers, standards-setting agencies, trade associations that provide specialized training, education, information, research and technical support” (Porter, 2000, p.17). The data for the social learning dialogue process was generated through an iterative analysis of dialogical social learning workshops, focus groups and semi-structured interviews. The analysis focused on the framing (Chapters 2, 3, and 5) and reframing of the AES (Chapter 6). Through dynamic engagement within the knowledge hub (contextual social learning and literature), the study surfaces a potential alternative discourse that actively includes the BSMFs as a crucial component of the commercial sector AES as the analysis shows these are largely excluded. This alternative discourse occurred through dialogical interactions with all participants via a pro-actively constituted social learning process, enriched and deepened by literature as indicated above. Main recommendations of the study are: 1. The AES must be framed to address the holistic value chain of BSMFs to help address underlying policy dualism, 2. Public Private Partnerships are needed to support BSMFs development and these should adopt a social learning approach that is reflective of complex realities 3. There is need for better understanding of roles and contributions of stakeholders in the AES to avoid duplications. , Thesis (MEd) -- Faculty of Education, Education, 2021
- Full Text:
- Date Issued: 2021-10
Gender and affirmative action in South Africa: A case study on women empowerment in the Department of Education in Mthatha district offices.: subtitle if needed. If no subtitle follow instructions in manual
- Authors: Mbatani, Mziwekaya Eric
- Date: 2012-09
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3207 , vital:43188
- Description: Abstract The main objective of this study has been to investigate the implementation of the affirmative action on the basis of gender balancing in the Department of Education in Mthatha District offices. The affirmative action policy is the program that seeks to remedy the past discrimination ideologies like on the bases of race and gender. Gender discrimination seemed to be the worst kind of discrimination in the past. Even within the same race, there are gender biases as well as within the same classes, women are treated differently. Some women are experiencing the impact of racial discrimination and class discrimination which puts women secondary of their same racial or same class male counterpart. Some men are experiencing only racial discrimination alone while others are experiencing class discrimination. Women serve the most severe discrimination of them all in the entire country of South Africa. Affirmative action has been used as a tool to eradicate all forms of discrimination. Hence its implementation needs to be evaluated to determine its impact on the eradication of discrimination, more especially sex discrimination. Evaluation has been made possible with the help of affirmative action measures which stipulate most of the principles of the affirmative action directed especially to the employers the gender balancing in the workplace is done with the aim of empowering and advancing women as their right according to gender equality. Women are experiencing the worst kind of social injustice have ever been practiced round the globe. Every woman is experiencing gender discrimination. Even in the rich family women are treated secondary by their male counterpart throughout their history of their living. In actual fact the presence of women in these family units is to help men help the men to have boys who will takeover the patriarchal duties assigned to every men as socialize to think and behave as the head of the families. If the family does not have boys who will later changed to be men, that family previously does run the risk of loosing the rights every households have where there are men. These girls to overcome the barriers of not having men and loose the right mention above they will marry men who will protect the right of their family. Previously, the family that did not have male will run the risk also of being robbed of their land and accused of black magic and the girls being raped. Some of the things that used to happen in the past are happening right now. Although women are promised the full dignity they deserve but some of the worst things that often happen to them in the past are still happening presently owing to the lack of political will to change the patriarchal system which is undermining the full dignity women deserve. This is viewed by Marxist feminists as being caused by the economic mode of production presently operating ‘capitalism’. The Marxist feminist suggests that there shall be no social justice if capitalism is still in place. Therefore they suggested that the only thing to eradicate is to eradicate the present form of production. The liberal feminist claim that the cause of the situation women found themselves is the unequal distribution of resource between men and women. Therefore they advocated that there should be equal rights between men and women as well as equal distribution of resources to men and women. Women must be empowered politically so as to have the equal voice like men. They must emanicipate themselves from the bondages of patriarchal ideologies. Women are just biological different from men but have equal mental capabilities as that of men. The equals should be treated equal and the unequals should be treated unequal. The differences we have should not be made as bases for treating others as unequal. The resources in our societies should be distributed equal among the demographics we have in our societies. The population of the country matters in terms of the countries prestige in terms of economic power. The more the population the country has the more powerful the country will be. In actual fact, the more productive the population of the country is the more productive the country will be. However, the less the productive the population of the country is, the lesser the productivity the country will be. Hence women should also be empowered economically. , Thesis (MMED) -- Faculty of HUMANITIES, SOCIAL SCIENCES and LAW, 2012
- Full Text:
- Date Issued: 2012-09
- Authors: Mbatani, Mziwekaya Eric
- Date: 2012-09
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/3207 , vital:43188
- Description: Abstract The main objective of this study has been to investigate the implementation of the affirmative action on the basis of gender balancing in the Department of Education in Mthatha District offices. The affirmative action policy is the program that seeks to remedy the past discrimination ideologies like on the bases of race and gender. Gender discrimination seemed to be the worst kind of discrimination in the past. Even within the same race, there are gender biases as well as within the same classes, women are treated differently. Some women are experiencing the impact of racial discrimination and class discrimination which puts women secondary of their same racial or same class male counterpart. Some men are experiencing only racial discrimination alone while others are experiencing class discrimination. Women serve the most severe discrimination of them all in the entire country of South Africa. Affirmative action has been used as a tool to eradicate all forms of discrimination. Hence its implementation needs to be evaluated to determine its impact on the eradication of discrimination, more especially sex discrimination. Evaluation has been made possible with the help of affirmative action measures which stipulate most of the principles of the affirmative action directed especially to the employers the gender balancing in the workplace is done with the aim of empowering and advancing women as their right according to gender equality. Women are experiencing the worst kind of social injustice have ever been practiced round the globe. Every woman is experiencing gender discrimination. Even in the rich family women are treated secondary by their male counterpart throughout their history of their living. In actual fact the presence of women in these family units is to help men help the men to have boys who will takeover the patriarchal duties assigned to every men as socialize to think and behave as the head of the families. If the family does not have boys who will later changed to be men, that family previously does run the risk of loosing the rights every households have where there are men. These girls to overcome the barriers of not having men and loose the right mention above they will marry men who will protect the right of their family. Previously, the family that did not have male will run the risk also of being robbed of their land and accused of black magic and the girls being raped. Some of the things that used to happen in the past are happening right now. Although women are promised the full dignity they deserve but some of the worst things that often happen to them in the past are still happening presently owing to the lack of political will to change the patriarchal system which is undermining the full dignity women deserve. This is viewed by Marxist feminists as being caused by the economic mode of production presently operating ‘capitalism’. The Marxist feminist suggests that there shall be no social justice if capitalism is still in place. Therefore they suggested that the only thing to eradicate is to eradicate the present form of production. The liberal feminist claim that the cause of the situation women found themselves is the unequal distribution of resource between men and women. Therefore they advocated that there should be equal rights between men and women as well as equal distribution of resources to men and women. Women must be empowered politically so as to have the equal voice like men. They must emanicipate themselves from the bondages of patriarchal ideologies. Women are just biological different from men but have equal mental capabilities as that of men. The equals should be treated equal and the unequals should be treated unequal. The differences we have should not be made as bases for treating others as unequal. The resources in our societies should be distributed equal among the demographics we have in our societies. The population of the country matters in terms of the countries prestige in terms of economic power. The more the population the country has the more powerful the country will be. In actual fact, the more productive the population of the country is the more productive the country will be. However, the less the productive the population of the country is, the lesser the productivity the country will be. Hence women should also be empowered economically. , Thesis (MMED) -- Faculty of HUMANITIES, SOCIAL SCIENCES and LAW, 2012
- Full Text:
- Date Issued: 2012-09
Assessing South African Medical Interns’ Experience and Confidence in Managing Obstetric Emergencies
- Authors: Miller, Andrew
- Date: 2021-02
- Subjects: Obstetrical emergencies
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/6882 , vital:52352
- Description: Background: Medical doctors in South Africa are required to complete a two-year internship at training hospitals, including a four-month rotation in obstetrics and gynaecology. Following this, doctors are allocated to community service posts; many of which are at district and primary level facilities where supervision is limited. The latest triennial Saving Mothers Report identified district hospitals as the second leading site for maternal deaths of all causes. District hospital were also the leading site for maternal deaths secondary to obstetric haemorrhage and the most likely site for the lack of a skilled doctor to be identified as a factor in deaths associated with caesarean delivery. Methods: This cross-sectional descriptive study aimed to describe the self-perceived readiness of medical interns completing their training to independently manage obstetric emergencies, based on the ESMOE modules in the HPCSA internship logbook. The research assessed medical interns in the last three months of their training, using a self-administered online questionnaire, with data collection between October and December 2019. Cluster sampling of interns at training facilities throughout the country resulted in a total of 182 respondents from 17 hospitals in seven provinces in the country, with an overall response rate of 34.1%. Results: Most interns had experience with, and confidence in, the management of miscarriage and hypertension in pregnancy. However, gaps in labour ward management, pregnancy related sepsis and surgical skills were identified. Only 42.3% of respondents were confident in their ability to diagnose obstructed labour, 26.3% had performed an assisted delivery, 39.0% were confident in their knowledge of the indications and contraindications of assisted deliveries and 35.7% had been involved in the delivery of a baby with shoulder dystocia. Regarding pregnancy related sepsis, 54.4% had experience with managing a wound abscess and 29.7% were confident managing puerperal endometritis. While 78.0% felt confident to perform a caesarean section, only 28.6% had performed uterine compression sutures for uterine atony at caesarean section. Additionally, there was a statistically significant variation in scores between training hospitals. Conclusion: A gap exists between the shortcomings in district hospital obstetric services, the prioritisation of placement of community service doctors at primary care and district hospitals, and the self-perceived readiness of medical interns completing their training to safely manage obstetric emergencies. This highlights the importance of clinical support for junior doctors at district hospitals and standardisation of intern training at accredited facilities across the country. , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-02
Assessing South African Medical Interns’ Experience and Confidence in Managing Obstetric Emergencies
- Authors: Miller, Andrew
- Date: 2021-02
- Subjects: Obstetrical emergencies
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/6882 , vital:52352
- Description: Background: Medical doctors in South Africa are required to complete a two-year internship at training hospitals, including a four-month rotation in obstetrics and gynaecology. Following this, doctors are allocated to community service posts; many of which are at district and primary level facilities where supervision is limited. The latest triennial Saving Mothers Report identified district hospitals as the second leading site for maternal deaths of all causes. District hospital were also the leading site for maternal deaths secondary to obstetric haemorrhage and the most likely site for the lack of a skilled doctor to be identified as a factor in deaths associated with caesarean delivery. Methods: This cross-sectional descriptive study aimed to describe the self-perceived readiness of medical interns completing their training to independently manage obstetric emergencies, based on the ESMOE modules in the HPCSA internship logbook. The research assessed medical interns in the last three months of their training, using a self-administered online questionnaire, with data collection between October and December 2019. Cluster sampling of interns at training facilities throughout the country resulted in a total of 182 respondents from 17 hospitals in seven provinces in the country, with an overall response rate of 34.1%. Results: Most interns had experience with, and confidence in, the management of miscarriage and hypertension in pregnancy. However, gaps in labour ward management, pregnancy related sepsis and surgical skills were identified. Only 42.3% of respondents were confident in their ability to diagnose obstructed labour, 26.3% had performed an assisted delivery, 39.0% were confident in their knowledge of the indications and contraindications of assisted deliveries and 35.7% had been involved in the delivery of a baby with shoulder dystocia. Regarding pregnancy related sepsis, 54.4% had experience with managing a wound abscess and 29.7% were confident managing puerperal endometritis. While 78.0% felt confident to perform a caesarean section, only 28.6% had performed uterine compression sutures for uterine atony at caesarean section. Additionally, there was a statistically significant variation in scores between training hospitals. Conclusion: A gap exists between the shortcomings in district hospital obstetric services, the prioritisation of placement of community service doctors at primary care and district hospitals, and the self-perceived readiness of medical interns completing their training to safely manage obstetric emergencies. This highlights the importance of clinical support for junior doctors at district hospitals and standardisation of intern training at accredited facilities across the country. , Thesis (Masters) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-02
Negotiation of Sex: A Study on Prevention Methods of Gender Based Violence amongst Intimate Partners of Ntabankulu
- Authors: Mketi, Funeka Gloria
- Date: 2014-10
- Subjects: Violent Crimes
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7550 , vital:54348
- Description: ABSTRACT The purpose of the study was to investigate whether negotiation of sex between intimate partners can be used as a prevention strategy of gender-based violence. The study included both female and male participants. Availability sampling technique was used to select the sample size of thirty. Participants were recruited from the street and data was collected in a private office. Participant’s ethical rights to confidentiality, anonymity, voluntary participation, and informed consent obtained prior taking part in the study were highly respected. Thirty questionnaires were used to collect data. Nature and prevalence of gender-based violence, attitudes, mechanisms and processes involved in negotiation of sex, and prevention strategies were investigated. Data was analyzed using Statistical Package of Social Sciences (SPSS) version 21.0. SPSS analyzed and summarized data into tables. Findings showed that prevalence of gender-based violence (GBV) in intimate partners is high. Negotiation of sex can be used as one of the prevention strategies, and the available processes and mechanisms of negotiating sex should be strengthened. Results also revealed that women empowerment in education and interventions focused on changing men’s attitude towards negotiation can help. Lastly, it appears that there is a need for capacitating both females and males with negotiation skills. , Thesis (Masters) -- Faculy of Humanities, Social Sciences and Law, 2014
- Full Text:
- Date Issued: 2014-10
- Authors: Mketi, Funeka Gloria
- Date: 2014-10
- Subjects: Violent Crimes
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/7550 , vital:54348
- Description: ABSTRACT The purpose of the study was to investigate whether negotiation of sex between intimate partners can be used as a prevention strategy of gender-based violence. The study included both female and male participants. Availability sampling technique was used to select the sample size of thirty. Participants were recruited from the street and data was collected in a private office. Participant’s ethical rights to confidentiality, anonymity, voluntary participation, and informed consent obtained prior taking part in the study were highly respected. Thirty questionnaires were used to collect data. Nature and prevalence of gender-based violence, attitudes, mechanisms and processes involved in negotiation of sex, and prevention strategies were investigated. Data was analyzed using Statistical Package of Social Sciences (SPSS) version 21.0. SPSS analyzed and summarized data into tables. Findings showed that prevalence of gender-based violence (GBV) in intimate partners is high. Negotiation of sex can be used as one of the prevention strategies, and the available processes and mechanisms of negotiating sex should be strengthened. Results also revealed that women empowerment in education and interventions focused on changing men’s attitude towards negotiation can help. Lastly, it appears that there is a need for capacitating both females and males with negotiation skills. , Thesis (Masters) -- Faculy of Humanities, Social Sciences and Law, 2014
- Full Text:
- Date Issued: 2014-10
The Impact of Direct Marketing on Consumer Buying Decisions in Mthatha’s Cosmetic Industry
- Authors: Mlobothi, Lusanda
- Date: 2022-00
- Subjects: Direct Marketing
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/8010 , vital:59302
- Description: This study aimed to investigate the impact of direct marketing on consumer buying decisions in Mthatha’s cosmetic industry. Direct marketing was measured by four dimensions, namely telemarketing, magazine advertisement, door-to-door selling and television home shopping. To achieve the aim, the research study adopted a positivist paradigm which was motivated by the quantitative approach using the explanatory research design. A self-administered questionnaire was issued to 300 respondents using the snowball sampling technique. The respondents were consumers that purchase cosmetic products sold through direct marketing channels in Mthatha. The key findings of the study, under the simple linear regression, revealed that telemarketing, magazine advertisements, and television home shopping influence consumer buying decisions in Mthatha’s cosmetic industry respectively. However, door-to-door selling does not influence consumer buying decisions in Mthatha’s cosmetic industry. Under the hierarchal regression analysis, the findings revealed that direct marketing influences consumer buying decisions after controlling for the respondents’ demographic variables (educational level, age, gender, marital status, and income level) in Mthatha’s cosmetic industry respectively. Based on the findings, policymakers should assist cosmetic organisations to progress from the manufacturing stage to the commercialisation stage. They should also provide capital and resources to small businesses to up-scale the size of the organisation. Based on the findings, this study will assist direct marketers to gain more understanding of how consumers think and the stages they undergo before making a purchase of a cosmetic product. Key words: Telemarketing, door-to-door selling, consumer buying decisions, television home shopping, magazine advertisements and direct marketing. , Thesis (Masters) -- Faculty of Commerce and Administration, 2022
- Full Text:
- Date Issued: 2022-00
- Authors: Mlobothi, Lusanda
- Date: 2022-00
- Subjects: Direct Marketing
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/8010 , vital:59302
- Description: This study aimed to investigate the impact of direct marketing on consumer buying decisions in Mthatha’s cosmetic industry. Direct marketing was measured by four dimensions, namely telemarketing, magazine advertisement, door-to-door selling and television home shopping. To achieve the aim, the research study adopted a positivist paradigm which was motivated by the quantitative approach using the explanatory research design. A self-administered questionnaire was issued to 300 respondents using the snowball sampling technique. The respondents were consumers that purchase cosmetic products sold through direct marketing channels in Mthatha. The key findings of the study, under the simple linear regression, revealed that telemarketing, magazine advertisements, and television home shopping influence consumer buying decisions in Mthatha’s cosmetic industry respectively. However, door-to-door selling does not influence consumer buying decisions in Mthatha’s cosmetic industry. Under the hierarchal regression analysis, the findings revealed that direct marketing influences consumer buying decisions after controlling for the respondents’ demographic variables (educational level, age, gender, marital status, and income level) in Mthatha’s cosmetic industry respectively. Based on the findings, policymakers should assist cosmetic organisations to progress from the manufacturing stage to the commercialisation stage. They should also provide capital and resources to small businesses to up-scale the size of the organisation. Based on the findings, this study will assist direct marketers to gain more understanding of how consumers think and the stages they undergo before making a purchase of a cosmetic product. Key words: Telemarketing, door-to-door selling, consumer buying decisions, television home shopping, magazine advertisements and direct marketing. , Thesis (Masters) -- Faculty of Commerce and Administration, 2022
- Full Text:
- Date Issued: 2022-00