Thorn tree of Jock of the Bushveld
- Authors: Eastern Province Herald
- Date: 1959-05-22
- Subjects: South Africa -- Folklore , Trees -- Mozambique -- Photographs
- Language: English
- Type: text , clippings , ephemera
- Identifier: http://hdl.handle.net/10962/72038 , vital:29990
- Description: Newspaper article: "This thorn tree, standing in the heart of Lourenco Marques business district, is reputed to be over 100 years old. Legend says it is the tree under which transport riders from the Transvaal used to outspan after the long trek to Delgoa Bay. It is also claimed as the tree under which Sir Percy Fitzpatrick and his immortal Jock camped before leaving for the interior.”
- Full Text: false
- Date Issued: 1959-05-22
- Authors: Eastern Province Herald
- Date: 1959-05-22
- Subjects: South Africa -- Folklore , Trees -- Mozambique -- Photographs
- Language: English
- Type: text , clippings , ephemera
- Identifier: http://hdl.handle.net/10962/72038 , vital:29990
- Description: Newspaper article: "This thorn tree, standing in the heart of Lourenco Marques business district, is reputed to be over 100 years old. Legend says it is the tree under which transport riders from the Transvaal used to outspan after the long trek to Delgoa Bay. It is also claimed as the tree under which Sir Percy Fitzpatrick and his immortal Jock camped before leaving for the interior.”
- Full Text: false
- Date Issued: 1959-05-22
Determinants of life satisfaction among race groups in South Africa
- Ebrahim, Amina, Botha, Ferdi, Snowball, Jeanette D
- Authors: Ebrahim, Amina , Botha, Ferdi , Snowball, Jeanette D
- Date: 2013
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69311 , vital:29497 , https://doi.org/10.1080/0376835x.2013.797227
- Description: Economic indicators, like gross domestic product per capita, are commonly used as indicators of welfare. However, they have a very limited and narrow scope, excluding many potentially important welfare determinants, such as health, relative income and religion – not surprising since they were not designed to fill this role. As a result, there is growing acceptance, and use of, subjective measures of well-being (called ‘happiness’ or ‘life satisfaction’, often used interchangeably) both worldwide and in South Africa. Happiness economics does not propose to replace income-based measures of well-being, but rather attempts to complement them with broader measures, which can be important in making policy decisions that optimise societal welfare. This paper tests for differences in subjective well-being between race groups in South Africa, and investigates the determinants of self-rated life satisfaction for each group. Using the 2008 National Income Dynamics Study data, descriptive methods (analysis of variance) and an ordered probit model are applied. Results indicate that reported life satisfaction differs substantially among race groups, with black South Africans being the least satisfied group despite changes since the advent of democracy in 1994. Higher levels of educational attainment increased satisfaction for the whole sample, and women (particularly black women) are generally less satisfied than men. As found in many other studies, unemployed people have lower levels of life satisfaction than the employed, even when controlling for income and relative income. The determinants of life satisfaction are also different for each race group: white South Africans attach greater importance to physical health, whereas employment status and absolute income matter greatly for black people. For coloured people and black people, positional status (as measured by relative income) is an important determinant of well-being, with religious involvement contributing significantly to the well-being of Indian people.
- Full Text: false
- Date Issued: 2013
- Authors: Ebrahim, Amina , Botha, Ferdi , Snowball, Jeanette D
- Date: 2013
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69311 , vital:29497 , https://doi.org/10.1080/0376835x.2013.797227
- Description: Economic indicators, like gross domestic product per capita, are commonly used as indicators of welfare. However, they have a very limited and narrow scope, excluding many potentially important welfare determinants, such as health, relative income and religion – not surprising since they were not designed to fill this role. As a result, there is growing acceptance, and use of, subjective measures of well-being (called ‘happiness’ or ‘life satisfaction’, often used interchangeably) both worldwide and in South Africa. Happiness economics does not propose to replace income-based measures of well-being, but rather attempts to complement them with broader measures, which can be important in making policy decisions that optimise societal welfare. This paper tests for differences in subjective well-being between race groups in South Africa, and investigates the determinants of self-rated life satisfaction for each group. Using the 2008 National Income Dynamics Study data, descriptive methods (analysis of variance) and an ordered probit model are applied. Results indicate that reported life satisfaction differs substantially among race groups, with black South Africans being the least satisfied group despite changes since the advent of democracy in 1994. Higher levels of educational attainment increased satisfaction for the whole sample, and women (particularly black women) are generally less satisfied than men. As found in many other studies, unemployed people have lower levels of life satisfaction than the employed, even when controlling for income and relative income. The determinants of life satisfaction are also different for each race group: white South Africans attach greater importance to physical health, whereas employment status and absolute income matter greatly for black people. For coloured people and black people, positional status (as measured by relative income) is an important determinant of well-being, with religious involvement contributing significantly to the well-being of Indian people.
- Full Text: false
- Date Issued: 2013
Hsp90 co-chaperones as drug targets in cancer: current perspectives
- Authors: Edkins, Adrienne L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66347 , vital:28938 , https://doi.org/10.1007/7355_2015_99
- Description: publisher version , Hsp90 is a molecular chaperone that regulates the function of numerous oncogenic transcription factors and signalling intermediates in the cell. Inhibition of Hsp90 is sufficient to induce the proteosomal degradation of many of these proteins, and as such, the Hsp90 chaperone has been regarded as a promising drug target. The appropriate functioning of the Hsp90 chaperone is dependent on its ATPase activity and interactions with a cohort of non-substrate accessory proteins known as co-chaperones. Co-chaperones associate with Hsp90 at all stages of the chaperone cycle and regulate a range of Hsp90 functions, including ATP hydrolysis and client protein binding and release. Given the ability of co-chaperones to organise the function of the Hsp90 molecular machine, these proteins are now regarded as potential drug targets. Herein the role of selected Hsp90 co-chaperones Hop, Cdc37, p23 and Aha1 as possible drug targets is discussed with a focus on cancer. , This work is based on the research supported by the South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa (Grant No 98566), the Cancer Association of South Africa (CANSA), Medical Research Council South Africa (MRC-SA) and Rhodes University. The views expressed are those of the authors and should not be attributed to the DST, NRF, CANSA, MRC-SA or Rhodes University. We apologize if we have inadvertently missed any important contributions to the field.
- Full Text: false
- Date Issued: 2016
- Authors: Edkins, Adrienne L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66347 , vital:28938 , https://doi.org/10.1007/7355_2015_99
- Description: publisher version , Hsp90 is a molecular chaperone that regulates the function of numerous oncogenic transcription factors and signalling intermediates in the cell. Inhibition of Hsp90 is sufficient to induce the proteosomal degradation of many of these proteins, and as such, the Hsp90 chaperone has been regarded as a promising drug target. The appropriate functioning of the Hsp90 chaperone is dependent on its ATPase activity and interactions with a cohort of non-substrate accessory proteins known as co-chaperones. Co-chaperones associate with Hsp90 at all stages of the chaperone cycle and regulate a range of Hsp90 functions, including ATP hydrolysis and client protein binding and release. Given the ability of co-chaperones to organise the function of the Hsp90 molecular machine, these proteins are now regarded as potential drug targets. Herein the role of selected Hsp90 co-chaperones Hop, Cdc37, p23 and Aha1 as possible drug targets is discussed with a focus on cancer. , This work is based on the research supported by the South African Research Chairs Initiative of the Department of Science and Technology and National Research Foundation of South Africa (Grant No 98566), the Cancer Association of South Africa (CANSA), Medical Research Council South Africa (MRC-SA) and Rhodes University. The views expressed are those of the authors and should not be attributed to the DST, NRF, CANSA, MRC-SA or Rhodes University. We apologize if we have inadvertently missed any important contributions to the field.
- Full Text: false
- Date Issued: 2016
Framing of transitional pedagogic practices in the sciences: enabling access
- Authors: Ellery, Karen
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66381 , vital:28942 , https://doi.org/10.1080/13562517.2017.1319812
- Description: publisher version , Educational literature shows that students from working-class backgrounds are significantly less likely to persist to completion in higher education than middle-class students. This paper draws theoretically and analytically on Bernstein’s ([1990. Class, Codes and Control, Volume IV: The Structuring of Pedagogic Discourse. London: Routledge; 2000. Pedagogy, Symbolic Control, and Identity: Theory, Research, Critique. Lanham: Rowman and Littlefield]) thesis that, through differential framing of pedagogic practices, the curriculum has capacity to accommodate all groups of students. Pedagogic practices in both a science foundation course and four first-year mainstream science courses in a higher education institution in the South African context are examined. Whilst the foundation course exhibits modalities that generally favour access, the mainstream courses have some modalities that appear to be constraining. It is argued from a social justice perspective that holistic curriculum transformations that better enable epistemic transitions are an urgent imperative, and that consideration of differential framing of pedagogic modalities offer a close-up empirical means of conceptualising such reforms.
- Full Text: false
- Date Issued: 2017
- Authors: Ellery, Karen
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66381 , vital:28942 , https://doi.org/10.1080/13562517.2017.1319812
- Description: publisher version , Educational literature shows that students from working-class backgrounds are significantly less likely to persist to completion in higher education than middle-class students. This paper draws theoretically and analytically on Bernstein’s ([1990. Class, Codes and Control, Volume IV: The Structuring of Pedagogic Discourse. London: Routledge; 2000. Pedagogy, Symbolic Control, and Identity: Theory, Research, Critique. Lanham: Rowman and Littlefield]) thesis that, through differential framing of pedagogic practices, the curriculum has capacity to accommodate all groups of students. Pedagogic practices in both a science foundation course and four first-year mainstream science courses in a higher education institution in the South African context are examined. Whilst the foundation course exhibits modalities that generally favour access, the mainstream courses have some modalities that appear to be constraining. It is argued from a social justice perspective that holistic curriculum transformations that better enable epistemic transitions are an urgent imperative, and that consideration of differential framing of pedagogic modalities offer a close-up empirical means of conceptualising such reforms.
- Full Text: false
- Date Issued: 2017
Petrology and geochemistry of early cretaceous bimodal continental flood volcanism of the NW Etendeka, Namibia Part 2: characteristics and petrogenesis of the high-Ti latite and high-Ti and low-Ti voluminous quartz latite eruptives
- Ewart, A, Marsh, Julian S, Milner, Simon C, Duncan, Andrew R, Kamber, B S, Armstrong, R A
- Authors: Ewart, A , Marsh, Julian S , Milner, Simon C , Duncan, Andrew R , Kamber, B S , Armstrong, R A
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150593 , vital:38987 , https://doi.org/10.1093/petrology/egg082
- Description: As a result of their relative concentration towards the respective Atlantic margins, the silicic eruptives of the Paraná (Brazil)–Etendeka large igneous province are disproportionately abundant in the Etendeka of Namibia. The NW Etendeka silicic units, dated at ∼132 Ma, occupy the upper stratigraphic levels of the volcanic sequences, restricted to the coastal zone, and comprise three latites and five quartz latites (QL).
- Full Text: false
- Date Issued: 2004
- Authors: Ewart, A , Marsh, Julian S , Milner, Simon C , Duncan, Andrew R , Kamber, B S , Armstrong, R A
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150593 , vital:38987 , https://doi.org/10.1093/petrology/egg082
- Description: As a result of their relative concentration towards the respective Atlantic margins, the silicic eruptives of the Paraná (Brazil)–Etendeka large igneous province are disproportionately abundant in the Etendeka of Namibia. The NW Etendeka silicic units, dated at ∼132 Ma, occupy the upper stratigraphic levels of the volcanic sequences, restricted to the coastal zone, and comprise three latites and five quartz latites (QL).
- Full Text: false
- Date Issued: 2004
Petrology and geochemistry of Early Cretaceous bimodal continental flood volcanism of the NW Etendeka, Namibia Part 1: introduction, mafic lavas and re-evaluation of mantle source components
- Ewart, A, Marsh, Julian S, Milner, Simon C, Duncan, Andrew R, Kamber, B S, Armstrong, R A
- Authors: Ewart, A , Marsh, Julian S , Milner, Simon C , Duncan, Andrew R , Kamber, B S , Armstrong, R A
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150583 , vital:38986 , https://doi.org/10.1093/petrology/egg083
- Description: The bimodal NW Etendeka province is located at the continental end of the Tristan plume trace in coastal Namibia. It comprises a high-Ti (Khumib type) and three low-Ti basalt (Tafelberg, Kuidas and Esmeralda types) suites, with, at stratigraphically higher level, interstratified high-Ti latites (three units) and quartz latites (five units), and one low-Ti quartz latite. Khumib basalts are enriched in high field strength elements and light rare earth elements relative to low-Ti types and exhibit trace element affinities with Tristan da Cunha lavas.
- Full Text: false
- Date Issued: 2004
- Authors: Ewart, A , Marsh, Julian S , Milner, Simon C , Duncan, Andrew R , Kamber, B S , Armstrong, R A
- Date: 2004
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/150583 , vital:38986 , https://doi.org/10.1093/petrology/egg083
- Description: The bimodal NW Etendeka province is located at the continental end of the Tristan plume trace in coastal Namibia. It comprises a high-Ti (Khumib type) and three low-Ti basalt (Tafelberg, Kuidas and Esmeralda types) suites, with, at stratigraphically higher level, interstratified high-Ti latites (three units) and quartz latites (five units), and one low-Ti quartz latite. Khumib basalts are enriched in high field strength elements and light rare earth elements relative to low-Ti types and exhibit trace element affinities with Tristan da Cunha lavas.
- Full Text: false
- Date Issued: 2004
Synthesis and evaluation of substituted 4-(N-benzylamino)cinnamate esters as potential anti-cancer agents and HIV-1 integrase inhibitors
- Faridoon, H, Edkins, Adrienne L, Isaacs, Michelle, Mnkandhla, Dumisani, Hoppe, Heinrich C, Kaye, Perry T
- Authors: Faridoon, H , Edkins, Adrienne L , Isaacs, Michelle , Mnkandhla, Dumisani , Hoppe, Heinrich C , Kaye, Perry T
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66289 , vital:28929 , https://doi.org/10.1016/j.bmcl.2016.05.023
- Description: publisher version , Encouraging selectivity and low micromolar activity against HeLa cervical carcinoma (IC50 ⩾ 3.0 μM) and the aggressive MDA-MB-231 triple negative breast carcinoma (IC50 ⩾ 9.6 μM) cell lines has been exhibited by a number of readily accessible 4-(N-benzylamino)cinnamate esters. The potential of the ligands as HIV-1 integrase inhibitors has also been examined.
- Full Text: false
- Date Issued: 2016
- Authors: Faridoon, H , Edkins, Adrienne L , Isaacs, Michelle , Mnkandhla, Dumisani , Hoppe, Heinrich C , Kaye, Perry T
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66289 , vital:28929 , https://doi.org/10.1016/j.bmcl.2016.05.023
- Description: publisher version , Encouraging selectivity and low micromolar activity against HeLa cervical carcinoma (IC50 ⩾ 3.0 μM) and the aggressive MDA-MB-231 triple negative breast carcinoma (IC50 ⩾ 9.6 μM) cell lines has been exhibited by a number of readily accessible 4-(N-benzylamino)cinnamate esters. The potential of the ligands as HIV-1 integrase inhibitors has also been examined.
- Full Text: false
- Date Issued: 2016
Aloe distans, Saldanha Bay
- Authors: Findlay, Dick
- Date: 1973
- Subjects: Aloe -- South Africa -- Illustrations , Botanical illustration -- South Africa
- Language: English
- Type: mixed material , illustrations , botanical illustrations
- Identifier: http://hdl.handle.net/10962/72604 , vital:30089
- Description: Caption: "Aloe distans, Saldanha Bay. Strandaalwyn, Saldanhabaai. 1973"
- Full Text: false
- Date Issued: 1973
- Authors: Findlay, Dick
- Date: 1973
- Subjects: Aloe -- South Africa -- Illustrations , Botanical illustration -- South Africa
- Language: English
- Type: mixed material , illustrations , botanical illustrations
- Identifier: http://hdl.handle.net/10962/72604 , vital:30089
- Description: Caption: "Aloe distans, Saldanha Bay. Strandaalwyn, Saldanhabaai. 1973"
- Full Text: false
- Date Issued: 1973
Aloe alooides, Eastern Transvaal
- Authors: Findlay, Dick
- Date: 1973
- Subjects: Aloe -- South Africa -- Illustrations , Botanical illustration -- South Africa
- Language: English
- Type: mixed material , illustrations , botanical illustrations
- Identifier: http://hdl.handle.net/10962/72614 , vital:30090
- Description: Caption: "Aloe alooides, Eastern Transvaal. 1973"
- Full Text: false
- Date Issued: 1973
- Authors: Findlay, Dick
- Date: 1973
- Subjects: Aloe -- South Africa -- Illustrations , Botanical illustration -- South Africa
- Language: English
- Type: mixed material , illustrations , botanical illustrations
- Identifier: http://hdl.handle.net/10962/72614 , vital:30090
- Description: Caption: "Aloe alooides, Eastern Transvaal. 1973"
- Full Text: false
- Date Issued: 1973
Aloe lutescens, Northern Transvaal
- Authors: Findlay, Dick
- Date: 1973
- Subjects: Aloe -- South Africa -- Illustrations , Botanical illustration -- South Africa
- Language: English
- Type: mixed material , illustrations , botanical illustrations
- Identifier: http://hdl.handle.net/10962/72577 , vital:30086
- Description: Caption: "Aloe lutescens, Northern Transvaal. Tshipiseaalwyn, Noord-Transvaal. 1973"
- Full Text: false
- Date Issued: 1973
- Authors: Findlay, Dick
- Date: 1973
- Subjects: Aloe -- South Africa -- Illustrations , Botanical illustration -- South Africa
- Language: English
- Type: mixed material , illustrations , botanical illustrations
- Identifier: http://hdl.handle.net/10962/72577 , vital:30086
- Description: Caption: "Aloe lutescens, Northern Transvaal. Tshipiseaalwyn, Noord-Transvaal. 1973"
- Full Text: false
- Date Issued: 1973
Stromatolite microbial communities as a source of new bioactive secondary metabolites
- Flatt, P M, Damarjanan, C, Isamonger, E, Kalinski, Jarmo-Charles J, Dorrington, Rosemary A, McPhail, Kerry L
- Authors: Flatt, P M , Damarjanan, C , Isamonger, E , Kalinski, Jarmo-Charles J , Dorrington, Rosemary A , McPhail, Kerry L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/65871 , vital:28851 , https://doi.org/10.1055/s-0036-1596638
- Description: publisher version , Stromatolites represent some of the earliest microbial communities on Earth. They are formed by accretion and precipitation of layered calcium carbonate structures that result from the metabolic activity of complex microbial communities and the geochemical conditions of their environment. Modern stromatolite communities include aerobic heterotrophs, sulphide-oxidizing bacteria, sulphate-reducing bacteria, fermentative bacteria and cyanobacteria. Phylogenetic analyses revealed the presence of new and known cyanobacterial taxa related to known producers of biologically active secondary metabolites in tufa stromatolites along the South African southeast coast [1]. Prompted us to investigate their potential for producing novel bioactive secondary metabolites. A series of three tide pools provided the opportunity to collect stromatolites along a vertical transect from pool A (highest elevation, low nitrogen input, fresh water), pool B (within high tide zone, brackish water) and pool C (within tidal zone). The microbial community in pool A is particularly distinct. Chemical extracts of stromatolites from different pools have been profiled by LC-MS/MS and the data subjected to molecular spectral networking using the GnPS platform [2] in order to establish the diversity and biological potential of the microbial metabolome that is being expressed within each of these microhabitats. Correlation of the phylogenetic and secondary metabolomic data is expected to guide the isolation of new natural products with biomedical relevance.
- Full Text: false
- Date Issued: 2016
- Authors: Flatt, P M , Damarjanan, C , Isamonger, E , Kalinski, Jarmo-Charles J , Dorrington, Rosemary A , McPhail, Kerry L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/65871 , vital:28851 , https://doi.org/10.1055/s-0036-1596638
- Description: publisher version , Stromatolites represent some of the earliest microbial communities on Earth. They are formed by accretion and precipitation of layered calcium carbonate structures that result from the metabolic activity of complex microbial communities and the geochemical conditions of their environment. Modern stromatolite communities include aerobic heterotrophs, sulphide-oxidizing bacteria, sulphate-reducing bacteria, fermentative bacteria and cyanobacteria. Phylogenetic analyses revealed the presence of new and known cyanobacterial taxa related to known producers of biologically active secondary metabolites in tufa stromatolites along the South African southeast coast [1]. Prompted us to investigate their potential for producing novel bioactive secondary metabolites. A series of three tide pools provided the opportunity to collect stromatolites along a vertical transect from pool A (highest elevation, low nitrogen input, fresh water), pool B (within high tide zone, brackish water) and pool C (within tidal zone). The microbial community in pool A is particularly distinct. Chemical extracts of stromatolites from different pools have been profiled by LC-MS/MS and the data subjected to molecular spectral networking using the GnPS platform [2] in order to establish the diversity and biological potential of the microbial metabolome that is being expressed within each of these microhabitats. Correlation of the phylogenetic and secondary metabolomic data is expected to guide the isolation of new natural products with biomedical relevance.
- Full Text: false
- Date Issued: 2016
Divisional map of Vryburg
- Authors: Fleming, J
- Date: 1907
- Subjects: Vryburg (South Africa) -- Maps , Scale 2,000 Cape roods = 1 inch , South Africa
- Language: English
- Type: cartographic , map
- Identifier: http://hdl.handle.net/10962/55001 , vital:26644 , Original map held by Cory Library for Humanities Research, Rhodes University Library, Grahamstown, South Africa , MP104
- Full Text: false
- Date Issued: 1907
- Authors: Fleming, J
- Date: 1907
- Subjects: Vryburg (South Africa) -- Maps , Scale 2,000 Cape roods = 1 inch , South Africa
- Language: English
- Type: cartographic , map
- Identifier: http://hdl.handle.net/10962/55001 , vital:26644 , Original map held by Cory Library for Humanities Research, Rhodes University Library, Grahamstown, South Africa , MP104
- Full Text: false
- Date Issued: 1907
Influence of annealing on thermoluminescence of natural quartz: kinetic analysis and experimental study of apparent inverse thermal quenching
- Folley, Damilola E, Chithambo, Makaiko L
- Authors: Folley, Damilola E , Chithambo, Makaiko L
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/109996 , vital:33212 , https://doi.org/10.1016/j.radmeas.2018.04.010
- Description: The influence of annealing on the main thermoluminescence glow-peak of natural quartz is reported. For comparison, results from un-annealed quartz are included. The glow-curve measured at 1 °Cs−1 after beta irradiation to 50 Gy revealed six peaks each for quartz annealed at 800 °C for 1 h and the un-annealed sample. The main peak in both quartzes was observed at 72 °C. This report focusses on kinetic analysis of the main peak. The analysis was carried out using various methods consisting of the initial rise, whole glow-peak, peak shape, variable heating rate and phosphorescence-based methods. The activation energy obtained using the various methods ranges between and for the annealed sample and between and for the un-annealed sample. The result suggests that annealing has little effect on the activation energy. The luminescence intensity decreased with heating rate in the un-annealed sample in a manner suggestive of thermal quenching. In contrast, the dependence of intensity on heating rate in the annealed sample is influenced by the dose the sample is irradiated to. Whereas thermal quenching was noted for a dose of 50 Gy in the un-annealed sample, the annealed sample showed evidence of thermal quenching at a low dose of 3 Gy with the opposite effect when irradiated to 50 Gy. The activation energies of thermal quenching were found as and for the un-annealed and annealed samples respectively. We ascribe the apparent dependence of thermal quenching on dose in the annealed sample to competition between radiative and non-radiative transitions at the recombination centre.
- Full Text: false
- Date Issued: 2018
- Authors: Folley, Damilola E , Chithambo, Makaiko L
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/109996 , vital:33212 , https://doi.org/10.1016/j.radmeas.2018.04.010
- Description: The influence of annealing on the main thermoluminescence glow-peak of natural quartz is reported. For comparison, results from un-annealed quartz are included. The glow-curve measured at 1 °Cs−1 after beta irradiation to 50 Gy revealed six peaks each for quartz annealed at 800 °C for 1 h and the un-annealed sample. The main peak in both quartzes was observed at 72 °C. This report focusses on kinetic analysis of the main peak. The analysis was carried out using various methods consisting of the initial rise, whole glow-peak, peak shape, variable heating rate and phosphorescence-based methods. The activation energy obtained using the various methods ranges between and for the annealed sample and between and for the un-annealed sample. The result suggests that annealing has little effect on the activation energy. The luminescence intensity decreased with heating rate in the un-annealed sample in a manner suggestive of thermal quenching. In contrast, the dependence of intensity on heating rate in the annealed sample is influenced by the dose the sample is irradiated to. Whereas thermal quenching was noted for a dose of 50 Gy in the un-annealed sample, the annealed sample showed evidence of thermal quenching at a low dose of 3 Gy with the opposite effect when irradiated to 50 Gy. The activation energies of thermal quenching were found as and for the un-annealed and annealed samples respectively. We ascribe the apparent dependence of thermal quenching on dose in the annealed sample to competition between radiative and non-radiative transitions at the recombination centre.
- Full Text: false
- Date Issued: 2018
Plan of properties bounded by High Street [Roberts Street], African Street, [Cawood Street] and [Spring Street] being Block F of the lands granted to the municipality, giving Lot number and specific details of Lot 63
- Authors: Ford, John H , Piers, W W
- Date: 1864
- Subjects: Grahamstown (South Africa) -- Maps Maps , Streets -- South Africa -- Maps Maps , South Africa
- Language: English
- Type: cartographic , map
- Identifier: http://hdl.handle.net/10962/57808 , vital:26991 , Cory Library for Humanities Research, Rhodes University Library, Grahamstown, South Africa MP1467 , MP1467
- Description: Divided and planned by Joh. H. Fort (1864) with later transfer subdivisions by W.R. Piers (1880).
- Full Text: false
- Date Issued: 1864
- Authors: Ford, John H , Piers, W W
- Date: 1864
- Subjects: Grahamstown (South Africa) -- Maps Maps , Streets -- South Africa -- Maps Maps , South Africa
- Language: English
- Type: cartographic , map
- Identifier: http://hdl.handle.net/10962/57808 , vital:26991 , Cory Library for Humanities Research, Rhodes University Library, Grahamstown, South Africa MP1467 , MP1467
- Description: Divided and planned by Joh. H. Fort (1864) with later transfer subdivisions by W.R. Piers (1880).
- Full Text: false
- Date Issued: 1864
Boundary of Griqualand West
- Ford, John H, W A Richards and Sons
- Authors: Ford, John H , W A Richards and Sons
- Date: 1883 , 1871
- Subjects: Griqualand West (South Africa) Maps , South Africa History 1836-1909 Maps
- Language: English
- Type: maps , digital maps , cartographic
- Identifier: http://hdl.handle.net/10962/105327 , vital:32498 , Cory Library for Humanities Research, Rhodes University Library, Grahamstown, South Africa , MP416d_e
- Description: Boundary of Griqualand West (MP416d)compiled by the Surveyor General's records from the surveys in progress by Mr. Surveyor J.H. Ford and from personal observation. Boundary beaconed by Mr.Surveyor Ford, recommended by Colonel Mosey, and approved MM Aby. Lithographed and printed by W.A. Richards and Son, Cape Town. Plan attached to the Griqualand West Northern Boundary Commission (MP416e), dated June 21, 1883 ; Boundary recommended the lines ST and TU, S. Melvill, 4th July 1883.
- Full Text: false
- Date Issued: 1883
- Authors: Ford, John H , W A Richards and Sons
- Date: 1883 , 1871
- Subjects: Griqualand West (South Africa) Maps , South Africa History 1836-1909 Maps
- Language: English
- Type: maps , digital maps , cartographic
- Identifier: http://hdl.handle.net/10962/105327 , vital:32498 , Cory Library for Humanities Research, Rhodes University Library, Grahamstown, South Africa , MP416d_e
- Description: Boundary of Griqualand West (MP416d)compiled by the Surveyor General's records from the surveys in progress by Mr. Surveyor J.H. Ford and from personal observation. Boundary beaconed by Mr.Surveyor Ford, recommended by Colonel Mosey, and approved MM Aby. Lithographed and printed by W.A. Richards and Son, Cape Town. Plan attached to the Griqualand West Northern Boundary Commission (MP416e), dated June 21, 1883 ; Boundary recommended the lines ST and TU, S. Melvill, 4th July 1883.
- Full Text: false
- Date Issued: 1883
Economic evaluation of water loss saving due to the biological control of water hyacinth at New Year’s Dam, Eastern Cape province, South Africa
- Fraser, Gavin C G, Hill, Martin P, Martin, J A
- Authors: Fraser, Gavin C G , Hill, Martin P , Martin, J A
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69341 , vital:29502 , https://doi.org/10.2989/16085914.2016.1151765
- Description: Water hyacinth Eichhornia crassipes is considered the most damaging aquatic weed in the world. However, few studies have quantified the impact of this weed economically and ecologically, and even fewer studies have quantified the benefits of its control. This paper focuses on water loss saving as the benefit derived from biological control of this plant between 1990 and 2013 at New Year’s Dam, Alicedale, Eastern Cape, South Africa. Estimates of water loss due to evapotranspiration from water hyacinth vary significantly; therefore, the study used three different rates, high, medium and low. A conservative raw agriculture value of R 0.26 per m3 was used to calculate the benefits derived by the water saved. The present benefit and cost values were determined using 10% and 5% discount rates. The benefit/cost ratio at the low evapotranspiration rate was less than one, implying that biological control was not economically viable but, at the higher evapotranspiration rates, the return justified the costs of biological control. However, at the marginal value product of water, the inclusion of the costs of damage to infrastructure, or the adverse effects of water hyacinth on biodiversity, would justify the use of biological control, even at the low transpiration rate.
- Full Text: false
- Date Issued: 2016
- Authors: Fraser, Gavin C G , Hill, Martin P , Martin, J A
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69341 , vital:29502 , https://doi.org/10.2989/16085914.2016.1151765
- Description: Water hyacinth Eichhornia crassipes is considered the most damaging aquatic weed in the world. However, few studies have quantified the impact of this weed economically and ecologically, and even fewer studies have quantified the benefits of its control. This paper focuses on water loss saving as the benefit derived from biological control of this plant between 1990 and 2013 at New Year’s Dam, Alicedale, Eastern Cape, South Africa. Estimates of water loss due to evapotranspiration from water hyacinth vary significantly; therefore, the study used three different rates, high, medium and low. A conservative raw agriculture value of R 0.26 per m3 was used to calculate the benefits derived by the water saved. The present benefit and cost values were determined using 10% and 5% discount rates. The benefit/cost ratio at the low evapotranspiration rate was less than one, implying that biological control was not economically viable but, at the higher evapotranspiration rates, the return justified the costs of biological control. However, at the marginal value product of water, the inclusion of the costs of damage to infrastructure, or the adverse effects of water hyacinth on biodiversity, would justify the use of biological control, even at the low transpiration rate.
- Full Text: false
- Date Issued: 2016
The role of doctoral education in early career academic development
- Frick, Liezel, Albertyn, Ruth, Brodin, Eva, McKenna, Sioux, Claessson, Silwa
- Authors: Frick, Liezel , Albertyn, Ruth , Brodin, Eva , McKenna, Sioux , Claessson, Silwa
- Date: 2017
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/66658 , vital:28978 , ISBN 9781928357216 , https://www.researchgate.net/publication/311427468/download
- Description: The social and economic significance of the doctorate is recognised across the world, as doctoral candidates are considered to be key contributors to the knowledge society by contributing to socio-economic development through innovation (Barnacle 2005; Taylor 2012). Doctoral students – regardless of their discipline – are expected to take part actively in the knowledge creation process at universities, and this is especially important for those who will remain in academia and continue to contribute in this way.1 But knowledge creation is a complex process. Knowledge creation at the doctoral level and beyond requires a comprehensive understanding of relevant knowledge, sound judgment, and the ability to advise with insight. Doctoral learning also includes aspects such as abstract reasoning, the ability to conceptualise, and problem solving. Thus, through the original contribution candidates are expected to create during the doctorate, they are supposed to become experts in their chosen field of study. This process has been described by Evans (2014) as disciplinary acculturation. Various authors (for example Danby & Lee 2012; Lin & Cranton 2005; Manathunga & Goozée 2007) point out that this process of becoming an expert is by no means easy or straightforward. Rather, developing as a scholar is a lifelong process in which moving from a novice to an expert is an essential rite of passage into academic practice (Dreyfus & Dreyfus 1986). Benmore (2014) states that for those pursuing academic careers, it involves coming to know, but also coming to be an academic. Such a process of becoming doctorate implies movement over time, progression, and transformation (Barnacle, 2005).
- Full Text: false
- Date Issued: 2017
- Authors: Frick, Liezel , Albertyn, Ruth , Brodin, Eva , McKenna, Sioux , Claessson, Silwa
- Date: 2017
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/66658 , vital:28978 , ISBN 9781928357216 , https://www.researchgate.net/publication/311427468/download
- Description: The social and economic significance of the doctorate is recognised across the world, as doctoral candidates are considered to be key contributors to the knowledge society by contributing to socio-economic development through innovation (Barnacle 2005; Taylor 2012). Doctoral students – regardless of their discipline – are expected to take part actively in the knowledge creation process at universities, and this is especially important for those who will remain in academia and continue to contribute in this way.1 But knowledge creation is a complex process. Knowledge creation at the doctoral level and beyond requires a comprehensive understanding of relevant knowledge, sound judgment, and the ability to advise with insight. Doctoral learning also includes aspects such as abstract reasoning, the ability to conceptualise, and problem solving. Thus, through the original contribution candidates are expected to create during the doctorate, they are supposed to become experts in their chosen field of study. This process has been described by Evans (2014) as disciplinary acculturation. Various authors (for example Danby & Lee 2012; Lin & Cranton 2005; Manathunga & Goozée 2007) point out that this process of becoming an expert is by no means easy or straightforward. Rather, developing as a scholar is a lifelong process in which moving from a novice to an expert is an essential rite of passage into academic practice (Dreyfus & Dreyfus 1986). Benmore (2014) states that for those pursuing academic careers, it involves coming to know, but also coming to be an academic. Such a process of becoming doctorate implies movement over time, progression, and transformation (Barnacle, 2005).
- Full Text: false
- Date Issued: 2017
A cytotoxic pentadecapeptide from a South African Didemnid tunicate
- Gallegos, D, Serrill, J, Parker-Nance, Shirley, Dorrington, Rosemary A, Ishmael, J, McPhail, Kerry L
- Authors: Gallegos, D , Serrill, J , Parker-Nance, Shirley , Dorrington, Rosemary A , Ishmael, J , McPhail, Kerry L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/65935 , vital:28863 , https://doi.org/10.1055/s-0036-1596683
- Description: publisher version , The rate of discovery of new natural product chemical entities has plateaued, and unique populations of endemic, biologically diverse sessile marine organisms represent increasingly critical opportunities to discover new chemistry. Discovery of the mandelalides [1] as potent inhibitors of cancer cell growth from the new South African tunicate Lissoclinum mandelai is an example of the diverse suites of metabolites with potent biological activities that have been isolated from tunicates and other filter-feeding sessile marine organisms that house complex microbial consortia. Further investigation of archived and new tunicate collections from Algoa Bay, South Africa, has revealed a group of didemnid tunicates with an unusual gelatinous morphology similar to Lissoclinum mandelai. Using a bioassay-guided isolation approach, a new “gelatinous” species of the genus Didemnum has yielded a cytotoxic pentadecapeptide with a molecular mass of 1603.7688 Da, comprising fifteen residues including both proteinogenic and non-proteinogenic amino acids. The pure compound inhibited both HeLa cervical cancer and NCI-H460 non-small cell lung cancer cell lines when tested at 30 nM in preliminary assays against cells seeded at low densities. Inhibition of cancer cells at low starting density may be indicative of an anti-proliferative mechanism of action. The compound did not show antibacterial activity against Vibrio cholera. Didemnin B and its clinically approved analogue dehydrodidemnin B (plitidepsin, Aplidin®) [2, 3] are important macrocyclic depsipeptides from a didemnid tunicate. The pentadecapeptide reported here provides justification for our continued investigation of unique, endemic didemnid tunicates from South Africa as a source of new macrocyclic natural products with cytotoxic, anti-viral or antimicrobial activity. , We acknowledge the South African government for permission to collect the subject tunicate (Collection Permit No. 278 RES2013/43)
- Full Text: false
- Date Issued: 2016
- Authors: Gallegos, D , Serrill, J , Parker-Nance, Shirley , Dorrington, Rosemary A , Ishmael, J , McPhail, Kerry L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/65935 , vital:28863 , https://doi.org/10.1055/s-0036-1596683
- Description: publisher version , The rate of discovery of new natural product chemical entities has plateaued, and unique populations of endemic, biologically diverse sessile marine organisms represent increasingly critical opportunities to discover new chemistry. Discovery of the mandelalides [1] as potent inhibitors of cancer cell growth from the new South African tunicate Lissoclinum mandelai is an example of the diverse suites of metabolites with potent biological activities that have been isolated from tunicates and other filter-feeding sessile marine organisms that house complex microbial consortia. Further investigation of archived and new tunicate collections from Algoa Bay, South Africa, has revealed a group of didemnid tunicates with an unusual gelatinous morphology similar to Lissoclinum mandelai. Using a bioassay-guided isolation approach, a new “gelatinous” species of the genus Didemnum has yielded a cytotoxic pentadecapeptide with a molecular mass of 1603.7688 Da, comprising fifteen residues including both proteinogenic and non-proteinogenic amino acids. The pure compound inhibited both HeLa cervical cancer and NCI-H460 non-small cell lung cancer cell lines when tested at 30 nM in preliminary assays against cells seeded at low densities. Inhibition of cancer cells at low starting density may be indicative of an anti-proliferative mechanism of action. The compound did not show antibacterial activity against Vibrio cholera. Didemnin B and its clinically approved analogue dehydrodidemnin B (plitidepsin, Aplidin®) [2, 3] are important macrocyclic depsipeptides from a didemnid tunicate. The pentadecapeptide reported here provides justification for our continued investigation of unique, endemic didemnid tunicates from South Africa as a source of new macrocyclic natural products with cytotoxic, anti-viral or antimicrobial activity. , We acknowledge the South African government for permission to collect the subject tunicate (Collection Permit No. 278 RES2013/43)
- Full Text: false
- Date Issued: 2016
A new species of Diplacanthus from the Late Devonian (Famennian) of South Africa
- Authors: Gess, Robert W
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/73873 , vital:30237 , https://doi.org/10.1016/S0753-3969(01)88002-2
- Description: An advanced diplacanthid (Climatiiformes) is described from a Famennian estuarine environment of South Africa. It is characterized by having exceptionally long thin fin spines and a deep body form. Unusual details of the fins and fin spine insertions are preserved. This is the first record of a diplacanthid from the Southern Hemisphere.
- Full Text: false
- Date Issued: 2009
- Authors: Gess, Robert W
- Date: 2009
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/73873 , vital:30237 , https://doi.org/10.1016/S0753-3969(01)88002-2
- Description: An advanced diplacanthid (Climatiiformes) is described from a Famennian estuarine environment of South Africa. It is characterized by having exceptionally long thin fin spines and a deep body form. Unusual details of the fins and fin spine insertions are preserved. This is the first record of a diplacanthid from the Southern Hemisphere.
- Full Text: false
- Date Issued: 2009
Late Devonian charophytes from the Witteberg Group, South Africa
- Gess, Robert W, Hiller, Norton
- Authors: Gess, Robert W , Hiller, Norton
- Date: 1995
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/72742 , vital:30106 , https://doi.org/10.1016/0034-6667(95)00007-8
- Description: The first record of Palaeozoic charophytes from southern Africa allows the establishment of two new genera to which are assigned four new species, Octochara crassa, O. gracilis. Hexachara setacea, and H. riniensis. Each species is represented by both vegetative and reproductive structures and suggested reconstructions are presented. Associated plant and animal remains, and the sedimentology and geochemistry of the containing rocks indicate that the charophytes probably grew in the shallow parts of a brackish coastal lagoon.
- Full Text: false
- Date Issued: 1995
- Authors: Gess, Robert W , Hiller, Norton
- Date: 1995
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/72742 , vital:30106 , https://doi.org/10.1016/0034-6667(95)00007-8
- Description: The first record of Palaeozoic charophytes from southern Africa allows the establishment of two new genera to which are assigned four new species, Octochara crassa, O. gracilis. Hexachara setacea, and H. riniensis. Each species is represented by both vegetative and reproductive structures and suggested reconstructions are presented. Associated plant and animal remains, and the sedimentology and geochemistry of the containing rocks indicate that the charophytes probably grew in the shallow parts of a brackish coastal lagoon.
- Full Text: false
- Date Issued: 1995