Metabolic activity throughout early development of dusky kob Argyrosomus japonicus (Sciaenidae)
- Edworthy, Carla, James, Nicola C, Erasmus, B, Kemp, J O G, Kaiser, Horst, Potts, Warren M
- Authors: Edworthy, Carla , James, Nicola C , Erasmus, B , Kemp, J O G , Kaiser, Horst , Potts, Warren M
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125159 , vital:35737 , https://doi.10.2989/1814232x.2018.1441907
- Description: Metabolism quantifies the energy-consuming activities of an organism (Nelson 2016) and is used as an indication of how organisms partition energy resources to activities that allow them to survive, grow and reproduce (Post and Lee 1996). The metabolic profile, which is a composition of the various metabolic rates of an individual, therefore gives an indication of the efficiency of energy transformation and allocation (Fry 1971; Brown et al. 2004). McKenzie et al. (2016) suggested that an organism’s physiology contributes towards its ability to survive under specific environmental conditions. As a result, physiological condition can be a reflection of the performance and fitness of an organism (Pörtner 2010). When combined with information on changing environmental conditions, physiological information can provide insight into species- and community-level responses (Pörtner and Farrell 2008). These kinds of data have served numerous ecological applications, including resource management, conservation (McKenzie et al. 2016) and climate-change assessments (Pörtner and Farrell 2008).
- Full Text:
- Date Issued: 2018
- Authors: Edworthy, Carla , James, Nicola C , Erasmus, B , Kemp, J O G , Kaiser, Horst , Potts, Warren M
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125159 , vital:35737 , https://doi.10.2989/1814232x.2018.1441907
- Description: Metabolism quantifies the energy-consuming activities of an organism (Nelson 2016) and is used as an indication of how organisms partition energy resources to activities that allow them to survive, grow and reproduce (Post and Lee 1996). The metabolic profile, which is a composition of the various metabolic rates of an individual, therefore gives an indication of the efficiency of energy transformation and allocation (Fry 1971; Brown et al. 2004). McKenzie et al. (2016) suggested that an organism’s physiology contributes towards its ability to survive under specific environmental conditions. As a result, physiological condition can be a reflection of the performance and fitness of an organism (Pörtner 2010). When combined with information on changing environmental conditions, physiological information can provide insight into species- and community-level responses (Pörtner and Farrell 2008). These kinds of data have served numerous ecological applications, including resource management, conservation (McKenzie et al. 2016) and climate-change assessments (Pörtner and Farrell 2008).
- Full Text:
- Date Issued: 2018
Legitimation of knowers for access in science
- Authors: Ellery, Karen
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70302 , vital:29643 , https://doi.org/10.1080/02602930701772788
- Description: Based on poor performance of students in the higher education science context, this paper questions the current focus on content knowledge and, in so doing, examines the role student knowers play in enabling epistemological access. Using Legitimation Code Theory, and drawing on data from interviews, course documents, observations, and critical reflections, the social relations of a science foundation course in the South African context are examined empirically to reveal the valuing of two kinds of knowers—learning-context knowers (or science learners) and production-context knowers (or scientists). Since being both kinds of knowers is necessary for access to powerful science knowledge, and home and educational contexts of certain groups of students are better in terms of enabling science knowers and learners than others, it is argued from a social justice perspective that science (and other) curricula account for knower attributes in enabling access for success for all students.
- Full Text:
- Date Issued: 2018
- Authors: Ellery, Karen
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/70302 , vital:29643 , https://doi.org/10.1080/02602930701772788
- Description: Based on poor performance of students in the higher education science context, this paper questions the current focus on content knowledge and, in so doing, examines the role student knowers play in enabling epistemological access. Using Legitimation Code Theory, and drawing on data from interviews, course documents, observations, and critical reflections, the social relations of a science foundation course in the South African context are examined empirically to reveal the valuing of two kinds of knowers—learning-context knowers (or science learners) and production-context knowers (or scientists). Since being both kinds of knowers is necessary for access to powerful science knowledge, and home and educational contexts of certain groups of students are better in terms of enabling science knowers and learners than others, it is argued from a social justice perspective that science (and other) curricula account for knower attributes in enabling access for success for all students.
- Full Text:
- Date Issued: 2018
Aquatic habitat shift assessment in a groundwater-fed semi-arid stream: an investigation into the response of Karoo hydroecology to system variability
- Authors: Ellis, Natalie
- Date: 2018
- Subjects: Aquatic habitats -- South Africa -- Karoo , Arid regions -- South Africa -- Karoo , Biotic communities -- South Africa -- Karoo , Stream ecology -- South Africa -- Karoo
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/61882 , vital:28072
- Description: From introduction: The subject of biological response to changes in aquatic habitat is one which has been well explored in many regions of the world. Examples include work in south east Spain by Mellado Diaz et al. (2008) and Oliva-Paterna et al. (2003), in western United States of America by Hauer and Lorang (2004), and in West Germany by Meyer et al. (2003). Similarly, a number of studies have been conducted in semi-arid regions, exploring elements such as erosion, climate, lithology and landscape formations (e.g. Boardman et al., 2013; Le Maitre et al., 2007; Meyer et al., 2003). However, apart from the study by Uys (1997), and Uys and O’Keeffe (1997), there is a noticeable lack of literature on aquatic habitat shifts in semi-arid stream systems, despite these systems being recognised for their high natural variability. This study provides a base-level approach to conducting habitat shift assessments in a semi-arid stream system and monitoring the hydroecological responses to system variability.
- Full Text:
- Date Issued: 2018
- Authors: Ellis, Natalie
- Date: 2018
- Subjects: Aquatic habitats -- South Africa -- Karoo , Arid regions -- South Africa -- Karoo , Biotic communities -- South Africa -- Karoo , Stream ecology -- South Africa -- Karoo
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/61882 , vital:28072
- Description: From introduction: The subject of biological response to changes in aquatic habitat is one which has been well explored in many regions of the world. Examples include work in south east Spain by Mellado Diaz et al. (2008) and Oliva-Paterna et al. (2003), in western United States of America by Hauer and Lorang (2004), and in West Germany by Meyer et al. (2003). Similarly, a number of studies have been conducted in semi-arid regions, exploring elements such as erosion, climate, lithology and landscape formations (e.g. Boardman et al., 2013; Le Maitre et al., 2007; Meyer et al., 2003). However, apart from the study by Uys (1997), and Uys and O’Keeffe (1997), there is a noticeable lack of literature on aquatic habitat shifts in semi-arid stream systems, despite these systems being recognised for their high natural variability. This study provides a base-level approach to conducting habitat shift assessments in a semi-arid stream system and monitoring the hydroecological responses to system variability.
- Full Text:
- Date Issued: 2018
Variation in perception of environmental change in nine Solomon Islands communities: implications for securing fairness in community-based adaptation
- Ensor, Jonathan Edward, Abernethy, Kirsten Elizabeth, Hoddy, Eric Timothy, Aswani, Shankar, Albert, Simon, Vaccaro, Ismael, Benedict, Jason Jon, Beare, Douglas James
- Authors: Ensor, Jonathan Edward , Abernethy, Kirsten Elizabeth , Hoddy, Eric Timothy , Aswani, Shankar , Albert, Simon , Vaccaro, Ismael , Benedict, Jason Jon , Beare, Douglas James
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145380 , vital:38433 , DOI: 10.1007/s10113-017-1242-1
- Description: Community-based approaches are pursued in recognition of the need for place-based responses to environmental change that integrate local understandings of risk and vulnerability. Yet the potential for fair adaptation is intimately linked to how variations in perceptions of environmental change and risk are treated. There is, however, little empirical evidence of the extent and nature of variations in risk perception in and between multiple community settings. Here, we rely on data from 231 semi-structured interviews conducted in nine communities in Western Province, Solomon Islands, to statistically model different perceptions of risk and change within and between communities.
- Full Text:
- Date Issued: 2018
- Authors: Ensor, Jonathan Edward , Abernethy, Kirsten Elizabeth , Hoddy, Eric Timothy , Aswani, Shankar , Albert, Simon , Vaccaro, Ismael , Benedict, Jason Jon , Beare, Douglas James
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145380 , vital:38433 , DOI: 10.1007/s10113-017-1242-1
- Description: Community-based approaches are pursued in recognition of the need for place-based responses to environmental change that integrate local understandings of risk and vulnerability. Yet the potential for fair adaptation is intimately linked to how variations in perceptions of environmental change and risk are treated. There is, however, little empirical evidence of the extent and nature of variations in risk perception in and between multiple community settings. Here, we rely on data from 231 semi-structured interviews conducted in nine communities in Western Province, Solomon Islands, to statistically model different perceptions of risk and change within and between communities.
- Full Text:
- Date Issued: 2018
Effects of CO2-induced ocean acidification on the early development, growth, survival and skeletogenesis of the estuarine-dependant sciaenid Argyrosomus japonicus
- Authors: Erasmus, Bernard
- Date: 2018
- Subjects: Argyrosomus , Argyrosomus -- Growth , Argyrosomus -- Mortality , Argyrosomus -- Ecology , Argyrosomus -- Physiology , Ocean acidification , Marine ecology -- South Africa , Carbon dioxide -- Physiological effect
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/60585 , vital:27799
- Description: Although it is increasingly accepted that ocean acidification poses a considerable threat to marine organisms, little is known about the likely response of fishes to this phenomenon. While initial research concluded that adult fishes may be tolerant to changes predicted in the next 300 years, the response of early life stages to end-of-century CO2 levels (~ 1100 µatm according to the IPCC RCP 8.5) remains unclear. To date, literature on the early growth and survival of fishes has yielded conflicting results, suggesting that vulnerability may be species dependant. The paucity of ocean acidification research on fishes is particularly evident when one considers larval skeletogenesis, with no robust studies on its impacts on bone and cartilage development. This study addresses the early life embryogenesis, hatching success, growth, skeletogenesis and survival of an estuarine-dependant species. Dusky kob (Argyrosomus japonicus) were reared in a control (pCO2 = 327.50 ± 80.07 qatm at pH 8.15), intermediate (pCO2 477.40 ± 59.46 qatm at pH 8.03) and high pCO2 treatment (pCO2 910.20 ± 136.45 qatm at pH 7.78) from egg to 29 days post-hatch (dph). Sixty individuals from each treatment were sacrificed at the egg stage and at 2, 6, 13, 18, 21 and 26 dph, measured and stained using an acid-free double- staining solution to prevent the deterioration of calcified matrices in fragile larval skeletons. The proportion of bone and cartilage was quantified at each stage using a novel pixel-counting method. Growth and skeletal development were identical between treatments until the onset of metamorphosis (21 dph). However, from the metamorphosis stage, the growth and skeletal development rate was significantly faster in the intermediate treatment and significantly slower in the high treatment when compared to the control treatment. By 26 dph, A. japonicus reared in high pCO2 were, on average, 47.2% smaller than the control treatment, and the relative proportion of bone in the body was 45.3% lower in the high pCO2 treatment when compared with the control. In addition, none of the fish in the high pCO2 treatment survived after 26 dph. It appears that the combination of the increased energy requirements during metamorphosis and the increased energy cost associated with acid-base regulation may account for reduced growth, skeletogenesis and poor survival in high pCO2. Regardless of the driver, the results of this study suggest that the pCO2 levels predicted for the end of the century may have negative effects on the growth, skeletal development, and survival during metamorphosis.
- Full Text:
- Date Issued: 2018
- Authors: Erasmus, Bernard
- Date: 2018
- Subjects: Argyrosomus , Argyrosomus -- Growth , Argyrosomus -- Mortality , Argyrosomus -- Ecology , Argyrosomus -- Physiology , Ocean acidification , Marine ecology -- South Africa , Carbon dioxide -- Physiological effect
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/60585 , vital:27799
- Description: Although it is increasingly accepted that ocean acidification poses a considerable threat to marine organisms, little is known about the likely response of fishes to this phenomenon. While initial research concluded that adult fishes may be tolerant to changes predicted in the next 300 years, the response of early life stages to end-of-century CO2 levels (~ 1100 µatm according to the IPCC RCP 8.5) remains unclear. To date, literature on the early growth and survival of fishes has yielded conflicting results, suggesting that vulnerability may be species dependant. The paucity of ocean acidification research on fishes is particularly evident when one considers larval skeletogenesis, with no robust studies on its impacts on bone and cartilage development. This study addresses the early life embryogenesis, hatching success, growth, skeletogenesis and survival of an estuarine-dependant species. Dusky kob (Argyrosomus japonicus) were reared in a control (pCO2 = 327.50 ± 80.07 qatm at pH 8.15), intermediate (pCO2 477.40 ± 59.46 qatm at pH 8.03) and high pCO2 treatment (pCO2 910.20 ± 136.45 qatm at pH 7.78) from egg to 29 days post-hatch (dph). Sixty individuals from each treatment were sacrificed at the egg stage and at 2, 6, 13, 18, 21 and 26 dph, measured and stained using an acid-free double- staining solution to prevent the deterioration of calcified matrices in fragile larval skeletons. The proportion of bone and cartilage was quantified at each stage using a novel pixel-counting method. Growth and skeletal development were identical between treatments until the onset of metamorphosis (21 dph). However, from the metamorphosis stage, the growth and skeletal development rate was significantly faster in the intermediate treatment and significantly slower in the high treatment when compared to the control treatment. By 26 dph, A. japonicus reared in high pCO2 were, on average, 47.2% smaller than the control treatment, and the relative proportion of bone in the body was 45.3% lower in the high pCO2 treatment when compared with the control. In addition, none of the fish in the high pCO2 treatment survived after 26 dph. It appears that the combination of the increased energy requirements during metamorphosis and the increased energy cost associated with acid-base regulation may account for reduced growth, skeletogenesis and poor survival in high pCO2. Regardless of the driver, the results of this study suggest that the pCO2 levels predicted for the end of the century may have negative effects on the growth, skeletal development, and survival during metamorphosis.
- Full Text:
- Date Issued: 2018
Challenging Biblical boundaries: Jeanette Winterson’s postmodern feminist subversion of Biblical discourse in Oranges are not the only fruit (1985) and Boating for beginners (1985)
- Authors: Erasmus, Shirley
- Date: 2018
- Subjects: Winterson, Jeanette, 1959- -- Criticism and interpretation , Bible -- Feminist criticism , Bible -- Criticism, interpretation, etc , Postmodernism -- Religious aspects , Winterson, Jeanette, 1959- -- Oranges are not the only fruit , Winterson, Jeanette, 1959- -- Boating for beginners , Patriarchy in literature , Sex discrimination in literature
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/59121 , vital:27430
- Description: This thesis investigates the subversion of Biblical discourse in Jeanette Winterson’s first two novels, Oranges are Not the Only Fruit and Boating for Beginners. By rewriting Biblical stories Winterson challenges traditional Western religious discourses and their rules for heteronormative social and sexual behaviours and desires. Winterson’s texts respond to the patriarchal nature of socially pervasive texts, such as the Bible, by encouraging her readers to regard these texts with suspicion, thus highlighting what can be seen as a ‘postmodern concern’ with the notion of ‘truth’. Chapter One of this thesis comprises a discussion of Biblical boundaries. These boundaries, I argue, are a process of historical oppression which serves to subjugate and control women, a practice inherent in the Bible and modern society. The Biblical boundaries within which women are expected to live, are carefully portrayed in Oranges and then comically and blasphemously mocked in Boating. Chapter One also argues that Winterson’s sexuality plays an important role in the understanding of her texts, despite her desire for her sexuality to remain ‘outside’ her writing. Chapter Two of this thesis, examines the mix of fact and fiction in Oranges, in order to create a new genre: fictional memoir. The chapter introduces the concept of the ‘autobiographical pact’ and the textual agreement which Winterson creates with her readers. In this chapter, I examine Winterson’s powerful subversion of Biblical discourse, through her narration of Jeanette’s ‘coming out’ within a Biblical framework. Chapter Three of this thesis examines Winterson’s second book, Boating, and the serious elements of this comic book. This chapter studies the various postmodern narrative techniques used in Boating in order to subvert Biblical and historical discourse. Chapter Three highlights Winterson’s postmodern concern with the construction of history as ‘truth’. Finally, Chapter Four compares Oranges and Boating, showing the texts as differing, yet equally relevant textual counterparts. This chapter examines the anti-feminine characters in both texts and Winterson’s ability to align her reader with a feminist or lesbian viewpoint. This thesis argues that Winterson’s first two texts deliberately challenge Biblical discourse in favour of a postmodern feminist viewpoint.
- Full Text:
- Date Issued: 2018
- Authors: Erasmus, Shirley
- Date: 2018
- Subjects: Winterson, Jeanette, 1959- -- Criticism and interpretation , Bible -- Feminist criticism , Bible -- Criticism, interpretation, etc , Postmodernism -- Religious aspects , Winterson, Jeanette, 1959- -- Oranges are not the only fruit , Winterson, Jeanette, 1959- -- Boating for beginners , Patriarchy in literature , Sex discrimination in literature
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/59121 , vital:27430
- Description: This thesis investigates the subversion of Biblical discourse in Jeanette Winterson’s first two novels, Oranges are Not the Only Fruit and Boating for Beginners. By rewriting Biblical stories Winterson challenges traditional Western religious discourses and their rules for heteronormative social and sexual behaviours and desires. Winterson’s texts respond to the patriarchal nature of socially pervasive texts, such as the Bible, by encouraging her readers to regard these texts with suspicion, thus highlighting what can be seen as a ‘postmodern concern’ with the notion of ‘truth’. Chapter One of this thesis comprises a discussion of Biblical boundaries. These boundaries, I argue, are a process of historical oppression which serves to subjugate and control women, a practice inherent in the Bible and modern society. The Biblical boundaries within which women are expected to live, are carefully portrayed in Oranges and then comically and blasphemously mocked in Boating. Chapter One also argues that Winterson’s sexuality plays an important role in the understanding of her texts, despite her desire for her sexuality to remain ‘outside’ her writing. Chapter Two of this thesis, examines the mix of fact and fiction in Oranges, in order to create a new genre: fictional memoir. The chapter introduces the concept of the ‘autobiographical pact’ and the textual agreement which Winterson creates with her readers. In this chapter, I examine Winterson’s powerful subversion of Biblical discourse, through her narration of Jeanette’s ‘coming out’ within a Biblical framework. Chapter Three of this thesis examines Winterson’s second book, Boating, and the serious elements of this comic book. This chapter studies the various postmodern narrative techniques used in Boating in order to subvert Biblical and historical discourse. Chapter Three highlights Winterson’s postmodern concern with the construction of history as ‘truth’. Finally, Chapter Four compares Oranges and Boating, showing the texts as differing, yet equally relevant textual counterparts. This chapter examines the anti-feminine characters in both texts and Winterson’s ability to align her reader with a feminist or lesbian viewpoint. This thesis argues that Winterson’s first two texts deliberately challenge Biblical discourse in favour of a postmodern feminist viewpoint.
- Full Text:
- Date Issued: 2018
Regional value chains and development integration in the SADC Region: the case of the pharmaceutical industry
- Authors: Faydherbe, Sean
- Date: 2018
- Subjects: Pharmaceutical industry -- Africa, Southern , Southern African Development Community , Africa, Southern -- Economic integration , Regional value chains (RVCs) , Global value chains (GVCs)
- Language: English
- Type: text , Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/62906 , vital:28309
- Description: This thesis investigates how regional value chains (RVCs) can be used to further development integration in the Southern African Development Community (SADC) region with a focus on the pharmaceutical manufacturing industry. The study is motivated by the apparent lack of attention given to the development of the pharmaceutical manufacturing industry in Southern Africa, the region’s high disease burden and the identification of the industry as economically and socially important by the SADC (2015) Industrialisation Strategy and Roadmap and the Department of Trade and Industry (DTI) (2017a) Industrial Policy Action Plan (IPAP). At the same time, South Africa and other countries in the region are exploring alternative approaches to regional integration, given the failure or stagnation of numerous formal integration arrangements throughout Africa, which have often lead to polarised rather than balanced development. This thesis argues that the development of RVCs within SADC may be an effective tool for development integration in the region, particularly in sectors such as pharmaceuticals. The study employs a value chain framework for the analysis and discusses development integration options, drawing on the East Asian experience with RVCs and on case studies involving India in the case of the pharmaceutical industry. It provides a sector profile of the industry in South Africa, due to its dominant status in the region, and also of Zimbabwe, due to that country’s potential to become a pharmaceutical industry leader in the region once again. The thesis first explores the important theoretical aspects underlying value chain analysis, namely governance and upgrading, while also outlining the rise of global value chains (GVCs). It analyses the complex relationships between RVCs and GVCs, and RVCs and regional integration. From this it concludes that RVCs are a stepping stone to participation in GVCs and that RVCs should be promoted within a development integration framework through strong regional cooperation. Value chain analysis is applied to the entire pharmaceutical manufacturing industry with a focus on SADC. The thesis examines how the sector is evolving with manufacturing multinational corporations (MNCs) outsourcing production and setting up centres of excellence in regional production hubs. The study argues that with the application of recommended policies, RVCs in sectors such as pharmaceutical manufacturing may provide a tool for achieving balanced development in the region. However, the study also finds that the pharmaceutical industry in SADC lags a long way behind the rest of the world and that many countries and firms will need to begin at the bottom of the value chain, with formulation, in order to contribute to the development of RVCs. The thesis concludes with recommendations on what policies are needed to foster the growth and development of pharmaceutical RVCs in the SADC region. These include strengthening public procurement, providing incentives for investment into the industry, incremental production and incremental export volumes, as well as certainty and predictability around the regulatory and business environment. Further, policy should aim to construct synergies and linkages on the ground between health systems and industrial developments; regulate service links important to pharmaceutical manufacturing; develop a coherent regional policy agenda; remove unnecessary non-tariff barriers to trade in the region and, in line with development integration, implement trade policy along with trade infrastructure that is efficient and includes airports, rail, roads and ports, as well as effective access to the internet.
- Full Text:
- Date Issued: 2018
- Authors: Faydherbe, Sean
- Date: 2018
- Subjects: Pharmaceutical industry -- Africa, Southern , Southern African Development Community , Africa, Southern -- Economic integration , Regional value chains (RVCs) , Global value chains (GVCs)
- Language: English
- Type: text , Thesis , Masters , MCom
- Identifier: http://hdl.handle.net/10962/62906 , vital:28309
- Description: This thesis investigates how regional value chains (RVCs) can be used to further development integration in the Southern African Development Community (SADC) region with a focus on the pharmaceutical manufacturing industry. The study is motivated by the apparent lack of attention given to the development of the pharmaceutical manufacturing industry in Southern Africa, the region’s high disease burden and the identification of the industry as economically and socially important by the SADC (2015) Industrialisation Strategy and Roadmap and the Department of Trade and Industry (DTI) (2017a) Industrial Policy Action Plan (IPAP). At the same time, South Africa and other countries in the region are exploring alternative approaches to regional integration, given the failure or stagnation of numerous formal integration arrangements throughout Africa, which have often lead to polarised rather than balanced development. This thesis argues that the development of RVCs within SADC may be an effective tool for development integration in the region, particularly in sectors such as pharmaceuticals. The study employs a value chain framework for the analysis and discusses development integration options, drawing on the East Asian experience with RVCs and on case studies involving India in the case of the pharmaceutical industry. It provides a sector profile of the industry in South Africa, due to its dominant status in the region, and also of Zimbabwe, due to that country’s potential to become a pharmaceutical industry leader in the region once again. The thesis first explores the important theoretical aspects underlying value chain analysis, namely governance and upgrading, while also outlining the rise of global value chains (GVCs). It analyses the complex relationships between RVCs and GVCs, and RVCs and regional integration. From this it concludes that RVCs are a stepping stone to participation in GVCs and that RVCs should be promoted within a development integration framework through strong regional cooperation. Value chain analysis is applied to the entire pharmaceutical manufacturing industry with a focus on SADC. The thesis examines how the sector is evolving with manufacturing multinational corporations (MNCs) outsourcing production and setting up centres of excellence in regional production hubs. The study argues that with the application of recommended policies, RVCs in sectors such as pharmaceutical manufacturing may provide a tool for achieving balanced development in the region. However, the study also finds that the pharmaceutical industry in SADC lags a long way behind the rest of the world and that many countries and firms will need to begin at the bottom of the value chain, with formulation, in order to contribute to the development of RVCs. The thesis concludes with recommendations on what policies are needed to foster the growth and development of pharmaceutical RVCs in the SADC region. These include strengthening public procurement, providing incentives for investment into the industry, incremental production and incremental export volumes, as well as certainty and predictability around the regulatory and business environment. Further, policy should aim to construct synergies and linkages on the ground between health systems and industrial developments; regulate service links important to pharmaceutical manufacturing; develop a coherent regional policy agenda; remove unnecessary non-tariff barriers to trade in the region and, in line with development integration, implement trade policy along with trade infrastructure that is efficient and includes airports, rail, roads and ports, as well as effective access to the internet.
- Full Text:
- Date Issued: 2018
Discovery and validation of a CD4 binding aptamer through Crossover SELEX towards the preliminary development of a point-of-care aptasensor for rapid CD4+ T-cell counting
- Authors: Fellows, Tamika
- Date: 2018
- Subjects: Uncatalogued
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/63527 , vital:28431
- Description: Expected release date-April 2020
- Full Text:
- Date Issued: 2018
- Authors: Fellows, Tamika
- Date: 2018
- Subjects: Uncatalogued
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/63527 , vital:28431
- Description: Expected release date-April 2020
- Full Text:
- Date Issued: 2018
Influence of knowledge of the end-point on pacing during a 2000m rowing time trial
- Authors: Ferreira, Dean
- Date: 2018
- Subjects: Rowing -- Training , Rowing -- Coaching , Endurance sports -- Training , Rowers -- Ability testing , Rowing -- Training -- Psychological aspects
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/61636 , vital:28044
- Description: Introduction: A typical 2000 m rowing race requires maximal force production over six to eight minutes. Optimal distribution of energetic resources during such a race is vital for optimal performance. There is little research examining the pacing strategies employed by rowers, particularly at the sub-elite level. Aim: The purpose of this investigation was to determine the influence of knowledge of the end-point on pacing during a 2000 m rowing time trial. Methods: Eleven male rowers from a university rowing club volunteered to partake in the study. Each participant completed three experimental trials on an indoor rowing ergometer, each 2000 m. The only difference between the trials was the nature of the information provided beforehand. At the start of the control trial, participants were correctly informed about the distance to be covered. Participants were not informed of the distance to be completed in the unknown trial. For the deceptive trial, participants were told 1000 m would be completed, but when this distance was reached, they were told to continue for another 1000 m. During each trial muscle activity, power output, heart rate, performance time and perceptions of effort were measured.Results: The control trial was significantly (p<0.05) faster than both the unknown and deceptive trials, however the deceptive trial was the fastest of all trials at the 1000 m distance. The unknown trial was slowest at 1000 m and at 2000 m. Muscle activity, RPE, heart rate and power output were significantly (p<0.05) lower in the unknown trial compared to the control and deceptive trial. The control trial exhibited a reverse J-shape pacing profile. The deceptive trial revealed a significant (p<0.05) reduction in performance time, heart rate, power output and muscle activity after the 1000 m interval. The first 500 m interval had the fastest performance and highest power output in all trials. In all trials, RPE was highest at the end of the 2000 m, the greatest reading being obtained at the end of the control trial. During the first 1000 m of the deceptive trial, the dependant variables were similar to those in the control trial. Once the deception was revealed, there was a significant (p<0.05) reduction in the muscle activity, heart rate and power output. Conclusion: The results of this study indicate that accurate end-point information is crucial to the development of an optimal pacing strategy, and ultimately to successful performance. Rowers tend to adopt the reverse J-shape pacing profile most often due to the tactical and physiological benefits offered by this strategy. Unknown or inaccurate end-point information resulted in performance decrements due to the uncertainty associated with the exercise bout.
- Full Text:
- Date Issued: 2018
- Authors: Ferreira, Dean
- Date: 2018
- Subjects: Rowing -- Training , Rowing -- Coaching , Endurance sports -- Training , Rowers -- Ability testing , Rowing -- Training -- Psychological aspects
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/61636 , vital:28044
- Description: Introduction: A typical 2000 m rowing race requires maximal force production over six to eight minutes. Optimal distribution of energetic resources during such a race is vital for optimal performance. There is little research examining the pacing strategies employed by rowers, particularly at the sub-elite level. Aim: The purpose of this investigation was to determine the influence of knowledge of the end-point on pacing during a 2000 m rowing time trial. Methods: Eleven male rowers from a university rowing club volunteered to partake in the study. Each participant completed three experimental trials on an indoor rowing ergometer, each 2000 m. The only difference between the trials was the nature of the information provided beforehand. At the start of the control trial, participants were correctly informed about the distance to be covered. Participants were not informed of the distance to be completed in the unknown trial. For the deceptive trial, participants were told 1000 m would be completed, but when this distance was reached, they were told to continue for another 1000 m. During each trial muscle activity, power output, heart rate, performance time and perceptions of effort were measured.Results: The control trial was significantly (p<0.05) faster than both the unknown and deceptive trials, however the deceptive trial was the fastest of all trials at the 1000 m distance. The unknown trial was slowest at 1000 m and at 2000 m. Muscle activity, RPE, heart rate and power output were significantly (p<0.05) lower in the unknown trial compared to the control and deceptive trial. The control trial exhibited a reverse J-shape pacing profile. The deceptive trial revealed a significant (p<0.05) reduction in performance time, heart rate, power output and muscle activity after the 1000 m interval. The first 500 m interval had the fastest performance and highest power output in all trials. In all trials, RPE was highest at the end of the 2000 m, the greatest reading being obtained at the end of the control trial. During the first 1000 m of the deceptive trial, the dependant variables were similar to those in the control trial. Once the deception was revealed, there was a significant (p<0.05) reduction in the muscle activity, heart rate and power output. Conclusion: The results of this study indicate that accurate end-point information is crucial to the development of an optimal pacing strategy, and ultimately to successful performance. Rowers tend to adopt the reverse J-shape pacing profile most often due to the tactical and physiological benefits offered by this strategy. Unknown or inaccurate end-point information resulted in performance decrements due to the uncertainty associated with the exercise bout.
- Full Text:
- Date Issued: 2018
The effect of human resources management practices on employee commitment: the case of Mnquma Local Municipality
- Fihla, Siphenathi https://orcid.org/0000-0001-9632-2650
- Authors: Fihla, Siphenathi https://orcid.org/0000-0001-9632-2650
- Date: 2018
- Subjects: Personnel management--South Africa , Municipal government--South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/24431 , vital:62790
- Description: This study evaluated the relationship between the Human Resource Management Practices (HRMP) and employee commitment. Results based on a sample from Mnquma Local Municipality indicate that these practices have a significant impact on employee commitment. This project will help to advance research on exploring the influence of organisational variables on commitment. Research purpose: The purpose of the study was to investigate the effects of human resources management practices on employee commitment at Mnquma Local Municipality. Motivation for the study: The study examines HRMP and employee commitment in the public sector. The relationship between the two may be of value to the municipality’s success. Research approach, design and method: A quantitative research approach was followed to carry out this study. Data were collected from a sample of 137 respondents in a selected municipality (Mnquma Local Municipality). A self-administered questionnaire was sent to respondents. Main findings: A significant relationship was found between HRMP and employee commitment. Practical or managerial implications: Findings may be relevant to practitioners, including strategic management researchers, policy-makers, directors, managers, and supervisors. The study could assist various practitioners directly or indirectly involved in private and public organisations to develop HRMP that improves employee commitment. Contribution or value-add: The study adds to the literature on HRMP and employee commitment among the public service. , Thesis (MCom) -- Faculty of Management and Commerce, 2018
- Full Text:
- Date Issued: 2018
- Authors: Fihla, Siphenathi https://orcid.org/0000-0001-9632-2650
- Date: 2018
- Subjects: Personnel management--South Africa , Municipal government--South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/24431 , vital:62790
- Description: This study evaluated the relationship between the Human Resource Management Practices (HRMP) and employee commitment. Results based on a sample from Mnquma Local Municipality indicate that these practices have a significant impact on employee commitment. This project will help to advance research on exploring the influence of organisational variables on commitment. Research purpose: The purpose of the study was to investigate the effects of human resources management practices on employee commitment at Mnquma Local Municipality. Motivation for the study: The study examines HRMP and employee commitment in the public sector. The relationship between the two may be of value to the municipality’s success. Research approach, design and method: A quantitative research approach was followed to carry out this study. Data were collected from a sample of 137 respondents in a selected municipality (Mnquma Local Municipality). A self-administered questionnaire was sent to respondents. Main findings: A significant relationship was found between HRMP and employee commitment. Practical or managerial implications: Findings may be relevant to practitioners, including strategic management researchers, policy-makers, directors, managers, and supervisors. The study could assist various practitioners directly or indirectly involved in private and public organisations to develop HRMP that improves employee commitment. Contribution or value-add: The study adds to the literature on HRMP and employee commitment among the public service. , Thesis (MCom) -- Faculty of Management and Commerce, 2018
- Full Text:
- Date Issued: 2018
The current utility of oligonucleotide aptamers in targeting the MUC1 mucin tumour marker
- Authors: Flanagan, Shane Patrick
- Date: 2018
- Subjects: Uncatalogued
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/62969 , vital:28348
- Description: Expected release date-April 2020
- Full Text:
- Date Issued: 2018
- Authors: Flanagan, Shane Patrick
- Date: 2018
- Subjects: Uncatalogued
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/62969 , vital:28348
- Description: Expected release date-April 2020
- Full Text:
- Date Issued: 2018
Influence of annealing on thermoluminescence of natural quartz: kinetic analysis and experimental study of apparent inverse thermal quenching
- Folley, Damilola E, Chithambo, Makaiko L
- Authors: Folley, Damilola E , Chithambo, Makaiko L
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/109996 , vital:33212 , https://doi.org/10.1016/j.radmeas.2018.04.010
- Description: The influence of annealing on the main thermoluminescence glow-peak of natural quartz is reported. For comparison, results from un-annealed quartz are included. The glow-curve measured at 1 °Cs−1 after beta irradiation to 50 Gy revealed six peaks each for quartz annealed at 800 °C for 1 h and the un-annealed sample. The main peak in both quartzes was observed at 72 °C. This report focusses on kinetic analysis of the main peak. The analysis was carried out using various methods consisting of the initial rise, whole glow-peak, peak shape, variable heating rate and phosphorescence-based methods. The activation energy obtained using the various methods ranges between and for the annealed sample and between and for the un-annealed sample. The result suggests that annealing has little effect on the activation energy. The luminescence intensity decreased with heating rate in the un-annealed sample in a manner suggestive of thermal quenching. In contrast, the dependence of intensity on heating rate in the annealed sample is influenced by the dose the sample is irradiated to. Whereas thermal quenching was noted for a dose of 50 Gy in the un-annealed sample, the annealed sample showed evidence of thermal quenching at a low dose of 3 Gy with the opposite effect when irradiated to 50 Gy. The activation energies of thermal quenching were found as and for the un-annealed and annealed samples respectively. We ascribe the apparent dependence of thermal quenching on dose in the annealed sample to competition between radiative and non-radiative transitions at the recombination centre.
- Full Text: false
- Date Issued: 2018
- Authors: Folley, Damilola E , Chithambo, Makaiko L
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/109996 , vital:33212 , https://doi.org/10.1016/j.radmeas.2018.04.010
- Description: The influence of annealing on the main thermoluminescence glow-peak of natural quartz is reported. For comparison, results from un-annealed quartz are included. The glow-curve measured at 1 °Cs−1 after beta irradiation to 50 Gy revealed six peaks each for quartz annealed at 800 °C for 1 h and the un-annealed sample. The main peak in both quartzes was observed at 72 °C. This report focusses on kinetic analysis of the main peak. The analysis was carried out using various methods consisting of the initial rise, whole glow-peak, peak shape, variable heating rate and phosphorescence-based methods. The activation energy obtained using the various methods ranges between and for the annealed sample and between and for the un-annealed sample. The result suggests that annealing has little effect on the activation energy. The luminescence intensity decreased with heating rate in the un-annealed sample in a manner suggestive of thermal quenching. In contrast, the dependence of intensity on heating rate in the annealed sample is influenced by the dose the sample is irradiated to. Whereas thermal quenching was noted for a dose of 50 Gy in the un-annealed sample, the annealed sample showed evidence of thermal quenching at a low dose of 3 Gy with the opposite effect when irradiated to 50 Gy. The activation energies of thermal quenching were found as and for the un-annealed and annealed samples respectively. We ascribe the apparent dependence of thermal quenching on dose in the annealed sample to competition between radiative and non-radiative transitions at the recombination centre.
- Full Text: false
- Date Issued: 2018
One-pot synthesis of graphene quantum dots–phthalocyanines supramolecular hybrid and the investigation of their photophysical properties
- Fomo, Gertrude, Achadu, Ojodomo John, Nyokong, Tebello
- Authors: Fomo, Gertrude , Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188126 , vital:44725 , xlink:href="https://doi.org/10.1007/s10853-017-1539-y"
- Description: The synthesis of graphene quantum dots (GQDs) using organic compounds as carbon sources via bottom-up approaches has been widely developed, whereas their hybrids with other materials have been previously achieved post-synthetically via multi-step procedures. A novel approach for the preparation of supramolecular hybrid conjugates of GQDs and phthalocyanines (Pcs) via an in situ one-step bottom-up route was employed in this study. The as-synthesized GQDs and their Pc conjugates were characterized using different spectroscopic techniques and their photophysicochemical properties evaluated. Notably, the singlet oxygen quantum yields of the Pcs in the presence of GQDs were found to be 0.51 and 0.74 for 1-GQDs and 2-GQDs, respectively, as compared to the Pcs alone (0.18 and 0.70 for complex 1 and 2, respectively). The increase in triplet quantum yield (ΦT) values is complemented by a decrease in fluorescence quantum yield (ΦF). ΦT value of 0.96 obtained for the complex 2 after conjugation with GQDs is better or higher than the value of 0.74 as reported in the literature when complex 2 was conjugated to semiconductor QDs. Hence, this novel approach resulted in the derivation of hybrid materials with potentials for various photophysicochemical applications such as photodynamic therapy and photocatalysis.
- Full Text:
- Date Issued: 2018
- Authors: Fomo, Gertrude , Achadu, Ojodomo John , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188126 , vital:44725 , xlink:href="https://doi.org/10.1007/s10853-017-1539-y"
- Description: The synthesis of graphene quantum dots (GQDs) using organic compounds as carbon sources via bottom-up approaches has been widely developed, whereas their hybrids with other materials have been previously achieved post-synthetically via multi-step procedures. A novel approach for the preparation of supramolecular hybrid conjugates of GQDs and phthalocyanines (Pcs) via an in situ one-step bottom-up route was employed in this study. The as-synthesized GQDs and their Pc conjugates were characterized using different spectroscopic techniques and their photophysicochemical properties evaluated. Notably, the singlet oxygen quantum yields of the Pcs in the presence of GQDs were found to be 0.51 and 0.74 for 1-GQDs and 2-GQDs, respectively, as compared to the Pcs alone (0.18 and 0.70 for complex 1 and 2, respectively). The increase in triplet quantum yield (ΦT) values is complemented by a decrease in fluorescence quantum yield (ΦF). ΦT value of 0.96 obtained for the complex 2 after conjugation with GQDs is better or higher than the value of 0.74 as reported in the literature when complex 2 was conjugated to semiconductor QDs. Hence, this novel approach resulted in the derivation of hybrid materials with potentials for various photophysicochemical applications such as photodynamic therapy and photocatalysis.
- Full Text:
- Date Issued: 2018
Low symmetric metallophthalocyanine modified electrode via click chemistry for simultaneous detection of heavy metals
- Fomo, Gertrude, Nwaji, Njemuwa, Nyokong, Tebello
- Authors: Fomo, Gertrude , Nwaji, Njemuwa , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187914 , vital:44709 , xlink:href="https://doi.org/10.1016/j.jelechem.2018.02.016"
- Description: Beside different methods and materials used to develop electrochemical sensors, the modification of the electrode using click reaction based on metallophthalocyanine (MPc) compounds are shown to improve the stability and sensitivity of the sensor. This work reported the development of electrochemical sensor for mercury (II), Lead (II), copper (II) and cadmium (II) ions detection based on the synthesized novel low symmetry alkyne terminated cobalt Phthalocyanine (CoPc) derivative. Differential pulse stripping voltammetry (DPSV) technique was employed for the first time in simultaneous determination of trace levels of the above metal ions using modified glassy carbon electrode (GCE) via click chemistry. Under the optimum experimental conditions, the anodic peak current is proportional to the concentrations of metal ions over a wide range of 0 to 0.1 mM with nanolevel detection limit of 81.94, 327.71, 55.87 and 347.06 nM and the sensitivity of 866.23 ± 5.48, 215.82 ± 2.16, 1979.48 ± 11.47 and 204.50 ± 1.10 μA/mM for Hg(II), Cu(II), Pb(II) and Cd(II), respectively. The selectivity of the clicked-CoPc modified GCE toward Hg(II), Cu(II), Pb(II), Cd(II) present no interference from these metals ions. The fabricated electrochemical sensor exhibited very good electrochemical properties such as good reproducibility, stability, reusability and is suitable for the detection of heavy metal ions in tap water in our laboratory.
- Full Text:
- Date Issued: 2018
- Authors: Fomo, Gertrude , Nwaji, Njemuwa , Nyokong, Tebello
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187914 , vital:44709 , xlink:href="https://doi.org/10.1016/j.jelechem.2018.02.016"
- Description: Beside different methods and materials used to develop electrochemical sensors, the modification of the electrode using click reaction based on metallophthalocyanine (MPc) compounds are shown to improve the stability and sensitivity of the sensor. This work reported the development of electrochemical sensor for mercury (II), Lead (II), copper (II) and cadmium (II) ions detection based on the synthesized novel low symmetry alkyne terminated cobalt Phthalocyanine (CoPc) derivative. Differential pulse stripping voltammetry (DPSV) technique was employed for the first time in simultaneous determination of trace levels of the above metal ions using modified glassy carbon electrode (GCE) via click chemistry. Under the optimum experimental conditions, the anodic peak current is proportional to the concentrations of metal ions over a wide range of 0 to 0.1 mM with nanolevel detection limit of 81.94, 327.71, 55.87 and 347.06 nM and the sensitivity of 866.23 ± 5.48, 215.82 ± 2.16, 1979.48 ± 11.47 and 204.50 ± 1.10 μA/mM for Hg(II), Cu(II), Pb(II) and Cd(II), respectively. The selectivity of the clicked-CoPc modified GCE toward Hg(II), Cu(II), Pb(II), Cd(II) present no interference from these metals ions. The fabricated electrochemical sensor exhibited very good electrochemical properties such as good reproducibility, stability, reusability and is suitable for the detection of heavy metal ions in tap water in our laboratory.
- Full Text:
- Date Issued: 2018
An Immersive Audio Control System Using Mobile Devices and Ethernet AVB-Capable Speakers:
- Foss, Richard, Devonport, Sean
- Authors: Foss, Richard , Devonport, Sean
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/426745 , vital:72388 , https://www.aes.org/e-lib/browse.cfm?elib=19714
- Description: Immersive Sound is commonly used to create the localization of sound sources above, below, and around listeners. To achieve this immersive goal, sound systems are employing an ever-increasing number of speakers. Given that immersive sound systems have large speaker configurations such as in cinemas, theaters, museums, and home theater installations, there is a need to provide control for these various contexts and also to provide a means of automating this control. An immersive sound system has been created that allows for the real-time control over sound source localization. It is a multi-user client/server system where the client devices are mobile devices, thereby allowing remote control over sound source localization. Touch and orientation capabilities of mobile devices are used for the generation of three-dimensional coordinates. The server receives localization control messages from the client and uses an Ethernet AVB (audio video bridging) network to distribute appropriate mix levels to speakers with built-in signal processing. These localization messages can be recorded by users for later playback.
- Full Text:
- Date Issued: 2018
- Authors: Foss, Richard , Devonport, Sean
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/426745 , vital:72388 , https://www.aes.org/e-lib/browse.cfm?elib=19714
- Description: Immersive Sound is commonly used to create the localization of sound sources above, below, and around listeners. To achieve this immersive goal, sound systems are employing an ever-increasing number of speakers. Given that immersive sound systems have large speaker configurations such as in cinemas, theaters, museums, and home theater installations, there is a need to provide control for these various contexts and also to provide a means of automating this control. An immersive sound system has been created that allows for the real-time control over sound source localization. It is a multi-user client/server system where the client devices are mobile devices, thereby allowing remote control over sound source localization. Touch and orientation capabilities of mobile devices are used for the generation of three-dimensional coordinates. The server receives localization control messages from the client and uses an Ethernet AVB (audio video bridging) network to distribute appropriate mix levels to speakers with built-in signal processing. These localization messages can be recorded by users for later playback.
- Full Text:
- Date Issued: 2018
In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants: Antrocaryon klaineanum (Anacardiaceae) and Diospyros conocarpa (Ebenaceae)
- Fouokeng, Y, Feusso, H M Feumo, Noundou, Xavier S, Krause, Rui W M, Teinkela, Jean E Mb, Wintjens, R, Hoppe, Heinrich C, Azebaze, Anatole G B, Vardamides, Juliette C, Isaacs, Michelle
- Authors: Fouokeng, Y , Feusso, H M Feumo , Noundou, Xavier S , Krause, Rui W M , Teinkela, Jean E Mb , Wintjens, R , Hoppe, Heinrich C , Azebaze, Anatole G B , Vardamides, Juliette C , Isaacs, Michelle
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/126653 , vital:35908 , https://doi.org/10.1016/j.sajb.2018.10.008
- Description: Antiplasmodial, antitrypanosomal and anti-HIV-1 activities of crude extracts, fractions and some isolated compounds from two Cameroonian medicinal plants: Antrocaryon klaineanum Pierre (Anacardiaceae) and Diospyros conocarpa Gürke ex K. Schum. (Ebenaceae) were assessed. The phytochemical studies led to the isolation of eight compounds (1–8) from Diospyros conocarpa and six compounds (6, 9–13) from Antrocaryon klaineanum. These compounds were identified as mangiferolic acid (1), 3β, 22(S)-dihydroxycycloart-24E-en-26-oic acid (2), lupeol (3), aridanin (4), betulin (5), betulinic acid (6), bergenin (7), D-quercitol(8), entilin C(9), entilin A(10), antrocarine A(11), 7R,20(S)-dihydroxy-4,24(28)-ergostadien-3-one(12) and stigmasterol glucoside (13). The criteria for activity were set as follows: an IC50 value
- Full Text:
- Date Issued: 2018
- Authors: Fouokeng, Y , Feusso, H M Feumo , Noundou, Xavier S , Krause, Rui W M , Teinkela, Jean E Mb , Wintjens, R , Hoppe, Heinrich C , Azebaze, Anatole G B , Vardamides, Juliette C , Isaacs, Michelle
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/126653 , vital:35908 , https://doi.org/10.1016/j.sajb.2018.10.008
- Description: Antiplasmodial, antitrypanosomal and anti-HIV-1 activities of crude extracts, fractions and some isolated compounds from two Cameroonian medicinal plants: Antrocaryon klaineanum Pierre (Anacardiaceae) and Diospyros conocarpa Gürke ex K. Schum. (Ebenaceae) were assessed. The phytochemical studies led to the isolation of eight compounds (1–8) from Diospyros conocarpa and six compounds (6, 9–13) from Antrocaryon klaineanum. These compounds were identified as mangiferolic acid (1), 3β, 22(S)-dihydroxycycloart-24E-en-26-oic acid (2), lupeol (3), aridanin (4), betulin (5), betulinic acid (6), bergenin (7), D-quercitol(8), entilin C(9), entilin A(10), antrocarine A(11), 7R,20(S)-dihydroxy-4,24(28)-ergostadien-3-one(12) and stigmasterol glucoside (13). The criteria for activity were set as follows: an IC50 value
- Full Text:
- Date Issued: 2018
A Cross-cultural analysis of the normative indicators of the Beck Depression Inventory II(BDI-II) and the Beck Anxiety Inventory (BAI) amongst young adults in the Eastern Cape,South Africa
- Fourie, Claire https://orcid.org/0000-0002-0255-204X
- Authors: Fourie, Claire https://orcid.org/0000-0002-0255-204X
- Date: 2018
- Subjects: Stress (Psychology) , Depression, Mental
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/25117 , vital:63979
- Description: Mental illness rates are climbing, locally and globally. The World Health Organization (2001) has claimed that one in four people will be affected by a psychiatric disorder during their lifetime. With this in mind, there is an array of psychometric assessment measures that are used as tools to assist in the mental health care field. Two such measures are the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory-II (BDI-II). These measures are used globally to assist with the diagnosis and treatment of depression and anxiety. However, in South Africa, a paucity of normative indicators exists. This research set out to determine if there are significant differences in performance on the BAI and BDI-II when comparing a sample from the Eastern Cape, South Africa, to the international norms. It was found that performances on the BAI between the local sample and the international sample did not differ significantly. The local sample, on average, performed 4.76 points lower on the BDI-II than those assessed in the international norms. A series of theoretical models are explored in elucidating the findings in this study. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2018
- Full Text:
- Date Issued: 2018
- Authors: Fourie, Claire https://orcid.org/0000-0002-0255-204X
- Date: 2018
- Subjects: Stress (Psychology) , Depression, Mental
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/25117 , vital:63979
- Description: Mental illness rates are climbing, locally and globally. The World Health Organization (2001) has claimed that one in four people will be affected by a psychiatric disorder during their lifetime. With this in mind, there is an array of psychometric assessment measures that are used as tools to assist in the mental health care field. Two such measures are the Beck Anxiety Inventory (BAI) and the Beck Depression Inventory-II (BDI-II). These measures are used globally to assist with the diagnosis and treatment of depression and anxiety. However, in South Africa, a paucity of normative indicators exists. This research set out to determine if there are significant differences in performance on the BAI and BDI-II when comparing a sample from the Eastern Cape, South Africa, to the international norms. It was found that performances on the BAI between the local sample and the international sample did not differ significantly. The local sample, on average, performed 4.76 points lower on the BDI-II than those assessed in the international norms. A series of theoretical models are explored in elucidating the findings in this study. , Thesis (MSoc) -- Faculty of Social Sciences and Humanities, 2018
- Full Text:
- Date Issued: 2018
Pursuing cost-effective secure network micro-segmentation
- Authors: Fürst, Mark Richard
- Date: 2018
- Subjects: Computer networks -- Security measures , Computer networks -- Access control , Firewalls (Computer security) , IPSec (Computer network protocol) , Network micro-segmentation
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/131106 , vital:36524
- Description: Traditional network segmentation allows discrete trust levels to be defined for different network segments, using physical firewalls or routers that control north-south traffic flowing between different interfaces. This technique reduces the attack surface area should an attacker breach one of the perimeter defences. However, east-west traffic flowing between endpoints within the same network segment does not pass through a firewall, and an attacker may be able to move laterally between endpoints within that segment. Network micro-segmentation was designed to address the challenge of controlling east-west traffic, and various solutions have been released with differing levels of capabilities and feature sets. These approaches range from simple network switch Access Control List based segmentation to complex hypervisor based software-defined security segments defined down to the individual workload, container or process level, and enforced via policy based security controls for each segment. Several commercial solutions for network micro-segmentation exist, but these are primarily focused on physical and cloud data centres, and are often accompanied by significant capital outlay and resource requirements. Given these constraints, this research determines whether existing tools provided with operating systems can be re-purposed to implement micro-segmentation and restrict east-west traffic within one or more network segments for a small-to-medium sized corporate network. To this end, a proof-of-concept lab environment was built with a heterogeneous mix of Windows and Linux virtual servers and workstations deployed in an Active Directory domain. The use of Group Policy Objects to deploy IPsec Server and Domain Isolation for controlling traffic between endpoints is examined, in conjunction with IPsec Authenticated Header and Encapsulating Security Payload modes as an additional layer of security. The outcome of the research shows that revisiting existing tools can enable organisations to implement an additional, cost-effective secure layer of defence in their network.
- Full Text:
- Date Issued: 2018
- Authors: Fürst, Mark Richard
- Date: 2018
- Subjects: Computer networks -- Security measures , Computer networks -- Access control , Firewalls (Computer security) , IPSec (Computer network protocol) , Network micro-segmentation
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/131106 , vital:36524
- Description: Traditional network segmentation allows discrete trust levels to be defined for different network segments, using physical firewalls or routers that control north-south traffic flowing between different interfaces. This technique reduces the attack surface area should an attacker breach one of the perimeter defences. However, east-west traffic flowing between endpoints within the same network segment does not pass through a firewall, and an attacker may be able to move laterally between endpoints within that segment. Network micro-segmentation was designed to address the challenge of controlling east-west traffic, and various solutions have been released with differing levels of capabilities and feature sets. These approaches range from simple network switch Access Control List based segmentation to complex hypervisor based software-defined security segments defined down to the individual workload, container or process level, and enforced via policy based security controls for each segment. Several commercial solutions for network micro-segmentation exist, but these are primarily focused on physical and cloud data centres, and are often accompanied by significant capital outlay and resource requirements. Given these constraints, this research determines whether existing tools provided with operating systems can be re-purposed to implement micro-segmentation and restrict east-west traffic within one or more network segments for a small-to-medium sized corporate network. To this end, a proof-of-concept lab environment was built with a heterogeneous mix of Windows and Linux virtual servers and workstations deployed in an Active Directory domain. The use of Group Policy Objects to deploy IPsec Server and Domain Isolation for controlling traffic between endpoints is examined, in conjunction with IPsec Authenticated Header and Encapsulating Security Payload modes as an additional layer of security. The outcome of the research shows that revisiting existing tools can enable organisations to implement an additional, cost-effective secure layer of defence in their network.
- Full Text:
- Date Issued: 2018
This is our story: iconography of carved doors and panels in Òyó Palace
- Authors: Fọlárànmí, Stephen
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145698 , vital:38459 , https://0-doi.org.wam.seals.ac.za/10.1162/afar_a_00402
- Description: This saying or prayer is one of the numerous expressions among the Yorùbá about the door and its significance, not only as a physical and important aspect of their architecture, but also in their language and culture. It also alludes to its pride of place as perhaps the most decorated element of Yorùbá architecture. From private homes, to the homes of the rich, shrines, and palaces, Yorùbá doors are usually imbued with a considerable array of images and icons that proclaims the owner's identity, religion, occupation. The Yorùbá are not unique in this respect. For example, among the Dogon, the door is as important as the house on which it is affixed. The granary, according to Willett (2002: 176), protects the the food stored inside it, while the door is seen or referred to as an element not only for physical protection, but also as a spiritual means of warding off unwanted spirits. It is reasonable, therefore, to expect the door to receive aesthetic attention by embellishment with an array of images.
- Full Text:
- Date Issued: 2018
- Authors: Fọlárànmí, Stephen
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145698 , vital:38459 , https://0-doi.org.wam.seals.ac.za/10.1162/afar_a_00402
- Description: This saying or prayer is one of the numerous expressions among the Yorùbá about the door and its significance, not only as a physical and important aspect of their architecture, but also in their language and culture. It also alludes to its pride of place as perhaps the most decorated element of Yorùbá architecture. From private homes, to the homes of the rich, shrines, and palaces, Yorùbá doors are usually imbued with a considerable array of images and icons that proclaims the owner's identity, religion, occupation. The Yorùbá are not unique in this respect. For example, among the Dogon, the door is as important as the house on which it is affixed. The granary, according to Willett (2002: 176), protects the the food stored inside it, while the door is seen or referred to as an element not only for physical protection, but also as a spiritual means of warding off unwanted spirits. It is reasonable, therefore, to expect the door to receive aesthetic attention by embellishment with an array of images.
- Full Text:
- Date Issued: 2018
Palace Courtyards in Iléṣà: a melting point of traditional Yorùbá architecture
- Fọlárànmí, Stephen, Adémúlẹyá, Babásẹhìndè
- Authors: Fọlárànmí, Stephen , Adémúlẹyá, Babásẹhìndè
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145873 , vital:38474 , https://news.clas.ufl.edu/palace-courtyards-in-ile%E1%B9%A3a-a-melting-point-of-traditional-yoruba-architecture/
- Description: The Yorùbá courtyard is an important architectural space in traditional Yorùbá architecture that has not received adequate scholarly attention. This paper examines the courtyards in the palace of certain chiefs and Ọwá Obòkun in Iléṣà, in southwest Nigeria. Fieldwork identified about ten courtyards in the palace of the Ọwá, four in the Rísàwè palace, and two in the palaces of the Léjọkà and Ọdọlé of Iléṣà. It uses these courtyards as models for courtyards in Yorùbá architecture. The study revealed that most of the courtyards in the Ọwá’s palace are generally not used for one specific function, though some are used mainly for religious purposes. The courtyards in the palaces of the chiefs are more functional, and better maintained than those of the Ọwá’s palace. The paper concludes that—considering their ancient and social function—the courtyards form a melting point within Yorùbá architecture. It suggests that efforts be made to ensure that the existing courtyards in these palaces are designated as landmark architecture and properly cared for to serve as tourist attractions.
- Full Text:
- Date Issued: 2018
- Authors: Fọlárànmí, Stephen , Adémúlẹyá, Babásẹhìndè
- Date: 2018
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/145873 , vital:38474 , https://news.clas.ufl.edu/palace-courtyards-in-ile%E1%B9%A3a-a-melting-point-of-traditional-yoruba-architecture/
- Description: The Yorùbá courtyard is an important architectural space in traditional Yorùbá architecture that has not received adequate scholarly attention. This paper examines the courtyards in the palace of certain chiefs and Ọwá Obòkun in Iléṣà, in southwest Nigeria. Fieldwork identified about ten courtyards in the palace of the Ọwá, four in the Rísàwè palace, and two in the palaces of the Léjọkà and Ọdọlé of Iléṣà. It uses these courtyards as models for courtyards in Yorùbá architecture. The study revealed that most of the courtyards in the Ọwá’s palace are generally not used for one specific function, though some are used mainly for religious purposes. The courtyards in the palaces of the chiefs are more functional, and better maintained than those of the Ọwá’s palace. The paper concludes that—considering their ancient and social function—the courtyards form a melting point within Yorùbá architecture. It suggests that efforts be made to ensure that the existing courtyards in these palaces are designated as landmark architecture and properly cared for to serve as tourist attractions.
- Full Text:
- Date Issued: 2018