Legal remedies against corruption: lessons from Guatemala
- Cordell, Cameron George Thomas
- Authors: Cordell, Cameron George Thomas
- Date: 2019
- Subjects: Remedies (Law) -- Guatemala , Remedies (Law) -- South Africa Criminal law -- Guatemala Criminal law -- South Africa Public law -- South Africa Public law -- Guatemala
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: http://hdl.handle.net/10948/38013 , vital:34281
- Description: Corruption is a crime which has affected all levels of government in South Africa. Despite the multi-agency system developed since the advent of democracy, levels of corruption are still on the rise, with greater levels of impunity. It is clear that reform is needed within South Africa’s anti-corruption framework. The state of Guatemala has meanwhile achieved results that have been described as transcendental in the fight against corruption, via a novel anti-corruption commission formed in collaboration with the United Nations, known as the Commission against Impunity in Guatemala (CICIG). This dissertation begins with an examination of the content of the crime of corruption via a historical approach – charting the course of corruption and effort to curb it from Ancient Greece, Mesoamerica and Africa, through the various legal systems that have resulted in the modern-day legal frameworks of South Africa and Guatemala. In doing so, a working definition of corruption has been developed – namely the unlawful and unethical enrichment of the self at the expense of the state. This definition aids in clearly defining proven instances of corruption within the public sector in modern South Africa. While corruption as a crime is generally clandestine in nature and difficult to deal with quantitatively, it is clearly demonstrated from the instances of corruption that have been proven that the offence is dealt with ineffectually by the existing policy and legal framework. Examinations of corruption scandals such as the capture of the state by private family corporations, to the collapse of South Africa’s Social Security Agency (SASSA), show that even when proven, corrupt politicians rarely face consequences for their actions. This is due to the lack of clarity in the primary legislation dealing with corruption – the Prevention and Combatting of Corrupt Activity Act (PRECCA), combined with a multi-agency approach wherein the various bodies tasked with combatting corruption are not working cohesively. The solution to this problem is a single commission to integrate the anti-corruption framework, as well as providing a fresh perspective about how to deal with the crime. The CICIG has served this role in Guatemala, resulting in successful investigations and prosecutions of former Presidents, judges and members of the legislature. It has achieved this by supporting and working with the existing anti-corruption bodies, as well as advising government on effective policy reform. It is further staffed by anti-corruption experts who are from the Central and South American region, providing a level of trust and regional knowledge. There is no bar in South African law for the creation of a similar international body. Such a move is necessary to provide a fresh outlook on the fight against corruption in South Africa. An international body, staffed by African anti-corruption experts, would be an effective means to work with the multi-agency system currently in place to aid it in working cohesively, but also to provide African solutions to the scourge of corruption through policy reform.
- Full Text:
- Date Issued: 2019
- Authors: Cordell, Cameron George Thomas
- Date: 2019
- Subjects: Remedies (Law) -- Guatemala , Remedies (Law) -- South Africa Criminal law -- Guatemala Criminal law -- South Africa Public law -- South Africa Public law -- Guatemala
- Language: English
- Type: Thesis , Masters , LLM
- Identifier: http://hdl.handle.net/10948/38013 , vital:34281
- Description: Corruption is a crime which has affected all levels of government in South Africa. Despite the multi-agency system developed since the advent of democracy, levels of corruption are still on the rise, with greater levels of impunity. It is clear that reform is needed within South Africa’s anti-corruption framework. The state of Guatemala has meanwhile achieved results that have been described as transcendental in the fight against corruption, via a novel anti-corruption commission formed in collaboration with the United Nations, known as the Commission against Impunity in Guatemala (CICIG). This dissertation begins with an examination of the content of the crime of corruption via a historical approach – charting the course of corruption and effort to curb it from Ancient Greece, Mesoamerica and Africa, through the various legal systems that have resulted in the modern-day legal frameworks of South Africa and Guatemala. In doing so, a working definition of corruption has been developed – namely the unlawful and unethical enrichment of the self at the expense of the state. This definition aids in clearly defining proven instances of corruption within the public sector in modern South Africa. While corruption as a crime is generally clandestine in nature and difficult to deal with quantitatively, it is clearly demonstrated from the instances of corruption that have been proven that the offence is dealt with ineffectually by the existing policy and legal framework. Examinations of corruption scandals such as the capture of the state by private family corporations, to the collapse of South Africa’s Social Security Agency (SASSA), show that even when proven, corrupt politicians rarely face consequences for their actions. This is due to the lack of clarity in the primary legislation dealing with corruption – the Prevention and Combatting of Corrupt Activity Act (PRECCA), combined with a multi-agency approach wherein the various bodies tasked with combatting corruption are not working cohesively. The solution to this problem is a single commission to integrate the anti-corruption framework, as well as providing a fresh perspective about how to deal with the crime. The CICIG has served this role in Guatemala, resulting in successful investigations and prosecutions of former Presidents, judges and members of the legislature. It has achieved this by supporting and working with the existing anti-corruption bodies, as well as advising government on effective policy reform. It is further staffed by anti-corruption experts who are from the Central and South American region, providing a level of trust and regional knowledge. There is no bar in South African law for the creation of a similar international body. Such a move is necessary to provide a fresh outlook on the fight against corruption in South Africa. An international body, staffed by African anti-corruption experts, would be an effective means to work with the multi-agency system currently in place to aid it in working cohesively, but also to provide African solutions to the scourge of corruption through policy reform.
- Full Text:
- Date Issued: 2019
Cheetah Acinonyx jubatus behaviour and resource use in response to other African large carnivores
- Authors: Cornhill, Kristina
- Date: 2019
- Subjects: Cheetahs -- Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/44735 , vital:38169
- Description: Competition occurs between species for shared resources. Subordinate species employ resource selection to shift their resource use away from that of dominant species in order to avoid the negative consequences of competition. Only in Africa is the post-Pleistocene large carnivore guild intact, consisting of lions Panthera leo, spotted hyaenas Crocuta crocuta, leopards Panthera pardus, cheetahs Acinonyx jubatus, and African wild dogs Lycaon pictus. Therefore, only in Africa can we explore how large carnivores co-exist with one another in a diverse community. Cheetahs are a subordinate member of the large carnivore guild due to their small stature and solitary nature. However, we still do not fully understand how competition shapes cheetah behaviour and resource use. I used cheetahs as a model subordinate predator to determine the behavioural responses and resource selection of cheetah in response to assumed competition from other large carnivores. I experimentally explored the behavioural response of cheetah to large carnivore scent sources (scats) and their presence at cheetah scent-marking sites to test for avoidance of such cues. Moreover, using unplanned experiments based on the resource use of cheetahs in the absence and then presence of lions (assessing space and time use by cheetah) and African wild dogs (assessing prey use by both species), I evaluated resource selection by cheetahs as a way to reduce competition with these large carnivores. In addition, I measured spatial and temporal partitioning between cheetahs and all four large carnivores at camera trap sites. Finally, I assessed whether cheetahs responded to competitors using a long term proactive response or a short term reactive response. I found that all four of the other large carnivores in the guild shaped cheetahs resource use, however, all did so on different axes in accordance with the niche complementarity hypothesis. Lions and spotted hyenas were avoided through time, African wild dogs through space and prey use, and lions and leopards on the spatiotemporal axis. Moreover, I show that cheetahs utilize a reactive response to competition that allows them to avoid risk while still obtaining necessary resources.
- Full Text:
- Date Issued: 2019
- Authors: Cornhill, Kristina
- Date: 2019
- Subjects: Cheetahs -- Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/44735 , vital:38169
- Description: Competition occurs between species for shared resources. Subordinate species employ resource selection to shift their resource use away from that of dominant species in order to avoid the negative consequences of competition. Only in Africa is the post-Pleistocene large carnivore guild intact, consisting of lions Panthera leo, spotted hyaenas Crocuta crocuta, leopards Panthera pardus, cheetahs Acinonyx jubatus, and African wild dogs Lycaon pictus. Therefore, only in Africa can we explore how large carnivores co-exist with one another in a diverse community. Cheetahs are a subordinate member of the large carnivore guild due to their small stature and solitary nature. However, we still do not fully understand how competition shapes cheetah behaviour and resource use. I used cheetahs as a model subordinate predator to determine the behavioural responses and resource selection of cheetah in response to assumed competition from other large carnivores. I experimentally explored the behavioural response of cheetah to large carnivore scent sources (scats) and their presence at cheetah scent-marking sites to test for avoidance of such cues. Moreover, using unplanned experiments based on the resource use of cheetahs in the absence and then presence of lions (assessing space and time use by cheetah) and African wild dogs (assessing prey use by both species), I evaluated resource selection by cheetahs as a way to reduce competition with these large carnivores. In addition, I measured spatial and temporal partitioning between cheetahs and all four large carnivores at camera trap sites. Finally, I assessed whether cheetahs responded to competitors using a long term proactive response or a short term reactive response. I found that all four of the other large carnivores in the guild shaped cheetahs resource use, however, all did so on different axes in accordance with the niche complementarity hypothesis. Lions and spotted hyenas were avoided through time, African wild dogs through space and prey use, and lions and leopards on the spatiotemporal axis. Moreover, I show that cheetahs utilize a reactive response to competition that allows them to avoid risk while still obtaining necessary resources.
- Full Text:
- Date Issued: 2019
Reimagining constructions of gender dysphoria: a dual systematic review using analytical psychology’s concept of individuation
- Authors: Couch, Matthew
- Date: 2019
- Subjects: Gender identity disorders , Gender identity , Individuation (Psychology)
- Language: English
- Type: text , Thesis , Masters , MScoSc
- Identifier: http://hdl.handle.net/10962/95184 , vital:31125
- Description: The process of conceptualization has long served to capture and represent our perceptions of the social world. Conceptual categories help to make sense of subjective experiences, and through discursive practices may come to construct conventional frameworks of knowledge. Consequently, frameworks operating as natural and immutable run the risk of ignoring the dynamic and diverse experiences of many individuals. Today, conceptual frameworks for gender identity are found as inadequately representing progressive social views on the existence of gender identities manifesting outside of the prevailing male-female binary. Within this space of conceptual contention, the diagnostic category of gender dysphoria has received considerable inspection and critique. In particular, it has been criticised as fundamentally controversial by classifying issues of identity within a clinical framework and, consequently, as contributing to the pathologization of all gender diverse individuals. Thus, efforts to reconceptualise and reimagine gender dysphoria may be found. In this research the concept of individuation, as understood within a framework of analytical psychology, is discussed as a potential consideration in reimagining the concept of gender dysphoria. An overarching framework of social constructionism was adopted within this research in examining how constructions of conventional knowledge come about through regulatory discursive and performative practices. The theoretical orientation of analytical psychology was used to frame the concept of individuation and its application to gender dysphoria. This perspective consulted queer theory as a further critical orientation toward the construction of gender identity. The chosen methodology took form as a dual systematic review using critical interpretive synthesis (CIS) to construct representative frameworks. Psychological literature on gender dysphoria (review 1) and individuation (review 2) was reviewed and synthesised. Review 1 identified conceptual inferences within the literature and assessed their role toward problematic gender discourse, while review 2 served as a contributory tool to critically assess whether the conceptual space was accommodating of the concept of individuation. Findings in review 1 identified contemporary gender dysphoria literature as reinforcing of problematic gender discourse. The prevailing clinical framework on gender dysphoria and gender nonconformity was iterated through conceptual constructs emphasising an experience of pathological distress or life dissatisfaction. As such, a cyclical pathologization of gender diversity is reconstructed through current representations within the literature. However, it was deduced that there are signs of resistance in the literature to the clinical model which challenge and counter the impact of problematic gender discourse. In review 2, individuation was framed by the literature as an intrapsychic facilitator supporting the integration of all aspects particular to the individual personality so that conscious identity becomes congruent with internal nature. Resultantly, one may experience psychosocial maturation and contribute to collective societal progression. For some, individuation prompts a differentiation from collective expectations in integrating one‘s inherent nature into expressed identity. Thus, gender nonconformity may be viewed as an expression of this differentiation when individuation drives the realization of this feature to be intrinsic and natural for the individual. Individuation was determined as incompatible with the category of gender dysphoria, but of value within the conceptual space where efforts to reimagine gender dysphoria are in place.
- Full Text:
- Date Issued: 2019
- Authors: Couch, Matthew
- Date: 2019
- Subjects: Gender identity disorders , Gender identity , Individuation (Psychology)
- Language: English
- Type: text , Thesis , Masters , MScoSc
- Identifier: http://hdl.handle.net/10962/95184 , vital:31125
- Description: The process of conceptualization has long served to capture and represent our perceptions of the social world. Conceptual categories help to make sense of subjective experiences, and through discursive practices may come to construct conventional frameworks of knowledge. Consequently, frameworks operating as natural and immutable run the risk of ignoring the dynamic and diverse experiences of many individuals. Today, conceptual frameworks for gender identity are found as inadequately representing progressive social views on the existence of gender identities manifesting outside of the prevailing male-female binary. Within this space of conceptual contention, the diagnostic category of gender dysphoria has received considerable inspection and critique. In particular, it has been criticised as fundamentally controversial by classifying issues of identity within a clinical framework and, consequently, as contributing to the pathologization of all gender diverse individuals. Thus, efforts to reconceptualise and reimagine gender dysphoria may be found. In this research the concept of individuation, as understood within a framework of analytical psychology, is discussed as a potential consideration in reimagining the concept of gender dysphoria. An overarching framework of social constructionism was adopted within this research in examining how constructions of conventional knowledge come about through regulatory discursive and performative practices. The theoretical orientation of analytical psychology was used to frame the concept of individuation and its application to gender dysphoria. This perspective consulted queer theory as a further critical orientation toward the construction of gender identity. The chosen methodology took form as a dual systematic review using critical interpretive synthesis (CIS) to construct representative frameworks. Psychological literature on gender dysphoria (review 1) and individuation (review 2) was reviewed and synthesised. Review 1 identified conceptual inferences within the literature and assessed their role toward problematic gender discourse, while review 2 served as a contributory tool to critically assess whether the conceptual space was accommodating of the concept of individuation. Findings in review 1 identified contemporary gender dysphoria literature as reinforcing of problematic gender discourse. The prevailing clinical framework on gender dysphoria and gender nonconformity was iterated through conceptual constructs emphasising an experience of pathological distress or life dissatisfaction. As such, a cyclical pathologization of gender diversity is reconstructed through current representations within the literature. However, it was deduced that there are signs of resistance in the literature to the clinical model which challenge and counter the impact of problematic gender discourse. In review 2, individuation was framed by the literature as an intrapsychic facilitator supporting the integration of all aspects particular to the individual personality so that conscious identity becomes congruent with internal nature. Resultantly, one may experience psychosocial maturation and contribute to collective societal progression. For some, individuation prompts a differentiation from collective expectations in integrating one‘s inherent nature into expressed identity. Thus, gender nonconformity may be viewed as an expression of this differentiation when individuation drives the realization of this feature to be intrinsic and natural for the individual. Individuation was determined as incompatible with the category of gender dysphoria, but of value within the conceptual space where efforts to reimagine gender dysphoria are in place.
- Full Text:
- Date Issued: 2019
Avoiding business failure in south africa
- Authors: Court, Nadine viargaret
- Date: 2019
- Subjects: Business failures -- Prevention -- South Africa , Business failures Success in business Business enterprises -- Management -- South Africa Small business -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/38024 , vital:34284
- Description: The purpose of this study was to develop a comprehensive framework to forecast that a business is entering a distressed situation and to identify the warning signs to look out for before it is too late to turn the business around in order to maintain a sustainable future. The possible solution lies in what business owners and management can do, and look out for, to avoid business failure. The intended contribution of the study was to design a framework for most businesses, especially SMMEs, to follow to avoid business failure. Therefore, it can be seen from this study that it is critical for business owners and management to be innovative in their business to achieve competitive advantage and, as such, remain sustainable. Stakeholder relationships are critical to achieving a competitive advantage. Financial Analysis, Technology Management, Innovation, Organisational Design and Risk Management are interrelated and are very inter-dependent when seeking to avoid business failure. However, innovation and technology management have a significant influence on business failure and, as such, are critical to the success of the business.
- Full Text:
- Date Issued: 2019
- Authors: Court, Nadine viargaret
- Date: 2019
- Subjects: Business failures -- Prevention -- South Africa , Business failures Success in business Business enterprises -- Management -- South Africa Small business -- South Africa
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/38024 , vital:34284
- Description: The purpose of this study was to develop a comprehensive framework to forecast that a business is entering a distressed situation and to identify the warning signs to look out for before it is too late to turn the business around in order to maintain a sustainable future. The possible solution lies in what business owners and management can do, and look out for, to avoid business failure. The intended contribution of the study was to design a framework for most businesses, especially SMMEs, to follow to avoid business failure. Therefore, it can be seen from this study that it is critical for business owners and management to be innovative in their business to achieve competitive advantage and, as such, remain sustainable. Stakeholder relationships are critical to achieving a competitive advantage. Financial Analysis, Technology Management, Innovation, Organisational Design and Risk Management are interrelated and are very inter-dependent when seeking to avoid business failure. However, innovation and technology management have a significant influence on business failure and, as such, are critical to the success of the business.
- Full Text:
- Date Issued: 2019
Fintech and the financial services industry in South Africa
- Authors: Crouse, Johann Jacques
- Date: 2019
- Subjects: Banks and banking -- Data processing , Banks and banking -- Technological innovations , Financial services industry -- Information technology , Banks and banking
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/38046 , vital:34311
- Description: A preliminary literature review indicated that little to no research exists on the Fintech phenomena in the South African context. The purpose of this study is to gain the perceptions of South African bankers on the Fintech phenomena and to develop a deeper understanding of the Fintech phenomena in the South African context. An empirical exploratory qualitative approach was employed and an interpretivism research paradigm was utilised. A detailed literature review was conducted into the Fintech phenomena as well as the financial services sector in South Africa. The use of purposive sampling was initiated, and the sample of the study consisted of five individuals who work for the largest South African banks. The data was gathered through in-depth structured interviews which consisted of ten predetermined research questions. Rich data was obtained which was then analysed through the use of content analysis and coding. This enabled the transcription of data and the extraction of codes which assisted in obtaining findings that answered the research question. Authenticity, rigor, trustworthiness and credibility criteria was applied from the onset and throughout the research study. The themes that emerged from the data analysis process were navigated so that findings could be reached by comparing the themes to previous literature. In conclusion, six themes emerged from the data analysis, namely; collaboration can create new markets and create market share, investing in Fintech to overcome legacy infrastructure by going digital, Fintech companies are more customer focused, balance regulation between protecting the industry and creating an innovative environment competition in future will be fiercer, competition is good for the performance of the financial services industry and the Fintech phenomena is positive for the banking industry. Certain findings and conclusions were drawn; regulations in South Africa do allow for innovation, regulation is not biased towards banks, banks innovate and collaborate through Fintech, Fintech is positive for the banking industry, South African banks are investing in preparation for Fintech, South African banks have limited budgets, there is no significant loss of market share for banks due to Fintech companies, market share can be gained by banks partnering with Fintech companies and the future of the financial services industry in South Africa.
- Full Text:
- Date Issued: 2019
- Authors: Crouse, Johann Jacques
- Date: 2019
- Subjects: Banks and banking -- Data processing , Banks and banking -- Technological innovations , Financial services industry -- Information technology , Banks and banking
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/38046 , vital:34311
- Description: A preliminary literature review indicated that little to no research exists on the Fintech phenomena in the South African context. The purpose of this study is to gain the perceptions of South African bankers on the Fintech phenomena and to develop a deeper understanding of the Fintech phenomena in the South African context. An empirical exploratory qualitative approach was employed and an interpretivism research paradigm was utilised. A detailed literature review was conducted into the Fintech phenomena as well as the financial services sector in South Africa. The use of purposive sampling was initiated, and the sample of the study consisted of five individuals who work for the largest South African banks. The data was gathered through in-depth structured interviews which consisted of ten predetermined research questions. Rich data was obtained which was then analysed through the use of content analysis and coding. This enabled the transcription of data and the extraction of codes which assisted in obtaining findings that answered the research question. Authenticity, rigor, trustworthiness and credibility criteria was applied from the onset and throughout the research study. The themes that emerged from the data analysis process were navigated so that findings could be reached by comparing the themes to previous literature. In conclusion, six themes emerged from the data analysis, namely; collaboration can create new markets and create market share, investing in Fintech to overcome legacy infrastructure by going digital, Fintech companies are more customer focused, balance regulation between protecting the industry and creating an innovative environment competition in future will be fiercer, competition is good for the performance of the financial services industry and the Fintech phenomena is positive for the banking industry. Certain findings and conclusions were drawn; regulations in South Africa do allow for innovation, regulation is not biased towards banks, banks innovate and collaborate through Fintech, Fintech is positive for the banking industry, South African banks are investing in preparation for Fintech, South African banks have limited budgets, there is no significant loss of market share for banks due to Fintech companies, market share can be gained by banks partnering with Fintech companies and the future of the financial services industry in South Africa.
- Full Text:
- Date Issued: 2019
He says, she says: ecosystem services and gender among indigenous communities in the Colombian Amazon
- Cruz-Garcia, Gisella S, Cubillos, Martha V, Torres-Vitolas, Carlos, Harvey, Celia A, Shackleton, Charlie M, Schreckenberg, Kate, Willcock, Simon, Navarrete-Frías, Carolina, Sachet, Erwan
- Authors: Cruz-Garcia, Gisella S , Cubillos, Martha V , Torres-Vitolas, Carlos , Harvey, Celia A , Shackleton, Charlie M , Schreckenberg, Kate , Willcock, Simon , Navarrete-Frías, Carolina , Sachet, Erwan
- Date: 2019
- Subjects: South Africa To be catalogued 1836-1909 Maps
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/179627 , vital:43128 , xlink:href="https://doi.org/10.1016/j.ecoser.2019.100921"
- Description: Although it has been hypothesized that men and women vary in the way they value ecosystem services, research on ecosystem services rarely incorporates a gender dimension. We conducted research with nine indigenous communities in the Colombian Amazon to understand which ecosystem services men and women perceive as most important for their wellbeing and to rank them according to locally-defined criteria of importance. Participants identified a total of 26 ecosystem services and 20 different ranking criteria. Ecosystem services such as land for agricultural fields (a supporting service), and provision of fish and medicinal plants were equally important for both men and women. Wild fruits and resources to make handicrafts were more frequently mentioned by women, whereas timber, materials for making tools and coca leaves were more frequently mentioned by men. There were also differences in the criteria used to value ecosystem services, with 11 criteria mentioned by both men and women, five mentioned exclusively by women and another four only by men. Our results suggest that taking gender differences into account in ecosystem services assessments may result in the prioritization of different services in conservation and sustainable development programs, and may lead to different outcomes for ecosystem service provision and local livelihoods.
- Full Text:
- Date Issued: 2019
- Authors: Cruz-Garcia, Gisella S , Cubillos, Martha V , Torres-Vitolas, Carlos , Harvey, Celia A , Shackleton, Charlie M , Schreckenberg, Kate , Willcock, Simon , Navarrete-Frías, Carolina , Sachet, Erwan
- Date: 2019
- Subjects: South Africa To be catalogued 1836-1909 Maps
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/179627 , vital:43128 , xlink:href="https://doi.org/10.1016/j.ecoser.2019.100921"
- Description: Although it has been hypothesized that men and women vary in the way they value ecosystem services, research on ecosystem services rarely incorporates a gender dimension. We conducted research with nine indigenous communities in the Colombian Amazon to understand which ecosystem services men and women perceive as most important for their wellbeing and to rank them according to locally-defined criteria of importance. Participants identified a total of 26 ecosystem services and 20 different ranking criteria. Ecosystem services such as land for agricultural fields (a supporting service), and provision of fish and medicinal plants were equally important for both men and women. Wild fruits and resources to make handicrafts were more frequently mentioned by women, whereas timber, materials for making tools and coca leaves were more frequently mentioned by men. There were also differences in the criteria used to value ecosystem services, with 11 criteria mentioned by both men and women, five mentioned exclusively by women and another four only by men. Our results suggest that taking gender differences into account in ecosystem services assessments may result in the prioritization of different services in conservation and sustainable development programs, and may lead to different outcomes for ecosystem service provision and local livelihoods.
- Full Text:
- Date Issued: 2019
Pharmacists’ perceptions of the effects of the Consumer Protection Act of 2008 on the pharmacy profession in South Africa: an exploratory study
- Authors: Cumberlege, Karin
- Date: 2019
- Subjects: South Africa -- Consumer Protection Act, 2008 , Consumer protection -- Law and legislation -- South Africa Pharmacists -- Legal status, laws, etc. -- South Africa Pharmacy -- Practice -- South Africa
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/38057 , vital:34312
- Description: The pharmacy profession is highly regulated through a number of statutes and codes all of which are devised in the public interest. The Consumer Protection Act, No 68 of 2008 (CPA) is a relatively recent addition to these regulatory measures and purports to protect consumers in their relations with suppliers, which includes the pharmacist-patient relationship. Heightened consumer awareness is increasing litigious consumer behaviour, making it important for pharmacists to be aware of their legal duties as providers of pharmaceutical care to consumers and therefore, to appreciate the potential implications of the CPA. This study aimed to determine South African pharmacists’ perceptions of the potential effect of the CPA on the pharmacy profession. Specific objectives included establishing the extent to which pharmacy law and ethics are incorporated into pharmacy curricula at various tertiary pharmacy institutions. The literature review identified the pharmacy categories providing pharmaceutical care services, whilst investigating medico-legal aspects of such services. Selected consumer rights in the CPA were considered in the context of pharmacists’ ethical obligations to consumers, thereby identifying potential areas of liability for pharmacists. Content and curriculum development pertaining to pharmacy education and training, focusing on pharmacy law and ethics, were assessed. A mixed methods research design was used to achieve the aim of the study. This included focus groups, telephone interviews, and a questionnaire survey amongst registered pharmacists. The themes identified in the focus groups were included in the telephone interviews. Likewise, themes identified from both the focus groups and telephone interviews, were incorporated in the questionnaire survey. The results identified a disparity in pharmacists’ education and training received from the respective tertiary pharmacy institutions. The results showed that pharmacists do not necessarily appreciate the potential implications of the CPA for pharmacists, portending an increased likelihood of liability. This finding also has implications for the training of pharmacists.
- Full Text:
- Date Issued: 2019
- Authors: Cumberlege, Karin
- Date: 2019
- Subjects: South Africa -- Consumer Protection Act, 2008 , Consumer protection -- Law and legislation -- South Africa Pharmacists -- Legal status, laws, etc. -- South Africa Pharmacy -- Practice -- South Africa
- Language: English
- Type: Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10948/38057 , vital:34312
- Description: The pharmacy profession is highly regulated through a number of statutes and codes all of which are devised in the public interest. The Consumer Protection Act, No 68 of 2008 (CPA) is a relatively recent addition to these regulatory measures and purports to protect consumers in their relations with suppliers, which includes the pharmacist-patient relationship. Heightened consumer awareness is increasing litigious consumer behaviour, making it important for pharmacists to be aware of their legal duties as providers of pharmaceutical care to consumers and therefore, to appreciate the potential implications of the CPA. This study aimed to determine South African pharmacists’ perceptions of the potential effect of the CPA on the pharmacy profession. Specific objectives included establishing the extent to which pharmacy law and ethics are incorporated into pharmacy curricula at various tertiary pharmacy institutions. The literature review identified the pharmacy categories providing pharmaceutical care services, whilst investigating medico-legal aspects of such services. Selected consumer rights in the CPA were considered in the context of pharmacists’ ethical obligations to consumers, thereby identifying potential areas of liability for pharmacists. Content and curriculum development pertaining to pharmacy education and training, focusing on pharmacy law and ethics, were assessed. A mixed methods research design was used to achieve the aim of the study. This included focus groups, telephone interviews, and a questionnaire survey amongst registered pharmacists. The themes identified in the focus groups were included in the telephone interviews. Likewise, themes identified from both the focus groups and telephone interviews, were incorporated in the questionnaire survey. The results identified a disparity in pharmacists’ education and training received from the respective tertiary pharmacy institutions. The results showed that pharmacists do not necessarily appreciate the potential implications of the CPA for pharmacists, portending an increased likelihood of liability. This finding also has implications for the training of pharmacists.
- Full Text:
- Date Issued: 2019
Comparative study of skipjack tuna Katsuwonus pelamis (Scombridae) fishery stocks from the South Atlantic and western Indian oceans
- Dahlet, Lol I, Downey-Breedt, Nicola, Arce, Gabriel, Sauer, Warwick H H, Gasalla, Maria A
- Authors: Dahlet, Lol I , Downey-Breedt, Nicola , Arce, Gabriel , Sauer, Warwick H H , Gasalla, Maria A
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/123988 , vital:35523 , https://doi.org/10.3989/scimar.04804.22C
- Description: Temporal and spatial fluctuations in the abundance of oceanic pelagic populations spread geographically around the globe are common (Cushing 1975). The causes of these fluctuations may be exogenous (environmental or anthropogenic) or endogenous to the organism (e.g. ontogenetic drivers) (Ricker 1954). This scenario applies to some tuna stocks, including the skipjack tuna, Katsuwonus pelamis (Linnaeus, 1758), known as bonito-listrado in Brazil, katunkel, or ocean bonito in South Africa, and godhaa (bigger) or kadumas (smaller) skipjack in the Maldives. The skipjack belongs to the family Scombridae and inhabits tropical and subtropical areas of the globe. On average, 85% of skipjack catch occurs in waters warmer than 24°C (Fonteneau 2003). This resource is of particular importance, accounting for 57% of the global industrial tuna catch in 2016, and is mainly processed by the canning industry. Skipjack catches totaled 2.79 million t in 2016 (ISSF 2018), and currently 8.5% of worldwide catches are made by the pole-and line fleet. In Brazil and the Maldives, the resource is well-known. Catches in Brazil were seen to increase until 2014, while in the Maldives, 2006 marked the beginning of a strong and unsettling decline that continued until recent years. Off South Africa, skipjack catches are 1000 to 10000 times lower than those from Brazil and the Maldives, and the highest catches were recorded in 2012.
- Full Text:
- Date Issued: 2019
- Authors: Dahlet, Lol I , Downey-Breedt, Nicola , Arce, Gabriel , Sauer, Warwick H H , Gasalla, Maria A
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/123988 , vital:35523 , https://doi.org/10.3989/scimar.04804.22C
- Description: Temporal and spatial fluctuations in the abundance of oceanic pelagic populations spread geographically around the globe are common (Cushing 1975). The causes of these fluctuations may be exogenous (environmental or anthropogenic) or endogenous to the organism (e.g. ontogenetic drivers) (Ricker 1954). This scenario applies to some tuna stocks, including the skipjack tuna, Katsuwonus pelamis (Linnaeus, 1758), known as bonito-listrado in Brazil, katunkel, or ocean bonito in South Africa, and godhaa (bigger) or kadumas (smaller) skipjack in the Maldives. The skipjack belongs to the family Scombridae and inhabits tropical and subtropical areas of the globe. On average, 85% of skipjack catch occurs in waters warmer than 24°C (Fonteneau 2003). This resource is of particular importance, accounting for 57% of the global industrial tuna catch in 2016, and is mainly processed by the canning industry. Skipjack catches totaled 2.79 million t in 2016 (ISSF 2018), and currently 8.5% of worldwide catches are made by the pole-and line fleet. In Brazil and the Maldives, the resource is well-known. Catches in Brazil were seen to increase until 2014, while in the Maldives, 2006 marked the beginning of a strong and unsettling decline that continued until recent years. Off South Africa, skipjack catches are 1000 to 10000 times lower than those from Brazil and the Maldives, and the highest catches were recorded in 2012.
- Full Text:
- Date Issued: 2019
The medicinal chemistry of selected halogenated diketopiperazines CYCLO(CIS-PRO-4F-PRO) and CYCLO(L-PHE-4I-VAL)
- Authors: Dakada, Vuyokazi
- Date: 2019
- Subjects: Medicinal plants , Drug development Cells -- Effect of drugs on
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/39370 , vital:35221
- Description: Generally, peptides are selective and efficacious compounds; as a result, they are the best candidates for drug discovery and development. Most peptide-based drugs have been approved for clinical use. The 2,5-Diketopiperazines (DKPs), also known as cyclic dipeptides, are simple compounds which come from nature. Many DKPs are extracted from animals and plants. For example, cyclo(Proline(Pro)-Leucine(Leu)), cyclo(Proline-Valine(Val)), cyclo(Proline-Phenylalanine(Phe)) etc. In this study cyclo(cis-Proline(Pro)-4F-Proline(Pro)) and cyclo(L- Phenylalanine(Phe)-4I- Valine (Val)) were synthesized from their linear esters using a method modified by Milne et al. (1992). This method yielded good results. However, cyclo(L-Phe-4I-Val) degraded due to physicochemical stability attributes caused by hygroscopicity and photosensitivity. Quantitative analysis and evaluation of physicochemical properties of each dipeptide was achieved by using scanning electron microscopy, thermal analysis (differential scanning calorimetry and thermogravimetric analysis) and X-ray powder diffraction. To determine the purity of the cyclic dipeptide, high performance liquid chromatography and thin layer chromatography was used. The structural elucidation of the cyclic dipeptides was carried by employing infrared spectroscopy, mass spectrometry, nuclear magnetic resonance spectroscopy and, molecular modelling and computational chemistry. The aim of this research was to discover possible biological activity of cyclo(cis-Pro-4-F-Pro) and cyclo(L-Phe-4I-Val) with respect to their antimicrobial, anticancer, anti-diabetic and haematological effects. Cyclo(cis-Pro-4Fluoro-Pro) had no inhibitory effect on the antimicrobial strains tested, and cyclo(L-Phe-4Iodo-Val) could not be tested as the compound decomposed.
- Full Text:
- Date Issued: 2019
- Authors: Dakada, Vuyokazi
- Date: 2019
- Subjects: Medicinal plants , Drug development Cells -- Effect of drugs on
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/39370 , vital:35221
- Description: Generally, peptides are selective and efficacious compounds; as a result, they are the best candidates for drug discovery and development. Most peptide-based drugs have been approved for clinical use. The 2,5-Diketopiperazines (DKPs), also known as cyclic dipeptides, are simple compounds which come from nature. Many DKPs are extracted from animals and plants. For example, cyclo(Proline(Pro)-Leucine(Leu)), cyclo(Proline-Valine(Val)), cyclo(Proline-Phenylalanine(Phe)) etc. In this study cyclo(cis-Proline(Pro)-4F-Proline(Pro)) and cyclo(L- Phenylalanine(Phe)-4I- Valine (Val)) were synthesized from their linear esters using a method modified by Milne et al. (1992). This method yielded good results. However, cyclo(L-Phe-4I-Val) degraded due to physicochemical stability attributes caused by hygroscopicity and photosensitivity. Quantitative analysis and evaluation of physicochemical properties of each dipeptide was achieved by using scanning electron microscopy, thermal analysis (differential scanning calorimetry and thermogravimetric analysis) and X-ray powder diffraction. To determine the purity of the cyclic dipeptide, high performance liquid chromatography and thin layer chromatography was used. The structural elucidation of the cyclic dipeptides was carried by employing infrared spectroscopy, mass spectrometry, nuclear magnetic resonance spectroscopy and, molecular modelling and computational chemistry. The aim of this research was to discover possible biological activity of cyclo(cis-Pro-4-F-Pro) and cyclo(L-Phe-4I-Val) with respect to their antimicrobial, anticancer, anti-diabetic and haematological effects. Cyclo(cis-Pro-4Fluoro-Pro) had no inhibitory effect on the antimicrobial strains tested, and cyclo(L-Phe-4Iodo-Val) could not be tested as the compound decomposed.
- Full Text:
- Date Issued: 2019
Understanding the experiences of Zimbabwean students as foreign students at South African universities: the case of Rhodes University
- Authors: Daki, Andile Lebohang
- Date: 2019
- Subjects: Rhodes University -- Students -- Attitudes , Zimbabwean college students -- South Africa , Zimbabwean college students -- South Africa -- Conduct of life , Zimbabwean college students -- South Africa -- Psychology
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/96225 , vital:31252
- Description: This thesis seeks to understand the cultural and social experiences of black Zimbabwean students, as foreign students, at Rhodes University in Grahamstown, South Africa. It examines the ways in which black Zimbabwean students negotiate the cultural, social and institutional milieu of Rhodes University, which is a former white English-medium university. In doing so, the thesis draws upon Interface theory because, once entering the university space, these students interpret the space and simultaneously negotiate their way in and through this space along cultural and social interfaces. The fieldwork for the thesis involved in-depth interviews with eighteen black Zimbabwean students at the university, stratified in terms of both gender and year of study. A focus on gender facilitated an understanding of possible differences between male and female Zimbabwean students in terms of social and cultural experiences; while a consideration of year of study allowed for an examination of possible shifts in negotiation over time, from first year to Master’s level. The findings demonstrate a range of challenges faced by black Zimbabwean students while at Rhodes University, some of which arise from differences between Zimbabwean and South African society. At the same time, there are considerable differences amongst black Zimbabwean students in relation to the manner in which negotiation took place. While some students negotiate the space through active socialising and assimilating into the local world and lives of South African students as well as the university’s institutional culture, other students negotiate the space through isolation and alienation. Overall, with regard to adjusting to the world of Rhodes and South Africa, students pursued different routes which, in the end, made sense to them.
- Full Text:
- Date Issued: 2019
- Authors: Daki, Andile Lebohang
- Date: 2019
- Subjects: Rhodes University -- Students -- Attitudes , Zimbabwean college students -- South Africa , Zimbabwean college students -- South Africa -- Conduct of life , Zimbabwean college students -- South Africa -- Psychology
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/96225 , vital:31252
- Description: This thesis seeks to understand the cultural and social experiences of black Zimbabwean students, as foreign students, at Rhodes University in Grahamstown, South Africa. It examines the ways in which black Zimbabwean students negotiate the cultural, social and institutional milieu of Rhodes University, which is a former white English-medium university. In doing so, the thesis draws upon Interface theory because, once entering the university space, these students interpret the space and simultaneously negotiate their way in and through this space along cultural and social interfaces. The fieldwork for the thesis involved in-depth interviews with eighteen black Zimbabwean students at the university, stratified in terms of both gender and year of study. A focus on gender facilitated an understanding of possible differences between male and female Zimbabwean students in terms of social and cultural experiences; while a consideration of year of study allowed for an examination of possible shifts in negotiation over time, from first year to Master’s level. The findings demonstrate a range of challenges faced by black Zimbabwean students while at Rhodes University, some of which arise from differences between Zimbabwean and South African society. At the same time, there are considerable differences amongst black Zimbabwean students in relation to the manner in which negotiation took place. While some students negotiate the space through active socialising and assimilating into the local world and lives of South African students as well as the university’s institutional culture, other students negotiate the space through isolation and alienation. Overall, with regard to adjusting to the world of Rhodes and South Africa, students pursued different routes which, in the end, made sense to them.
- Full Text:
- Date Issued: 2019
Adult circumcision practices of traditional surgeons and nurses in relation to the initiates’ health outcomes/morbidity in the Eastern Cape
- Authors: Dalasa, Siyamthemba
- Date: 2019
- Subjects: Circumcision -- Social aspects
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10353/17029 , vital:40834
- Description: BACKGROUND Despite the adverse outcomes associated with traditional male circumcision, the practice remains prevalent, especially in the Eastern Cape, South, Africa. This study seeks to assess the practices of traditional surgeons and nurses in relation to the prevention and control of infections and their understanding of human physiological mechanisms during circumcision processes. METHOD This study has adopted a qualitative design, which involved conducting 115 semistructured interviews among traditional surgeons, traditional nurses and traditionally circumcised men, and one focus group discussion among traditional nurses. The data generated were transcribed and subjected to thematic content analysis. RESULTS The analysis revealed that both traditional surgeons and nurses demonstrated both poor aseptic techniques and a lack of knowledge of how the human body functions. Their lack of knowledge of basic human physiology meant that they trivialised sepsis in the penile wound. In addition, the seclusion lodges for circumcision and initiates living were unclean and uninhabitable. CONCLUSION The poor aseptic techniques of traditional surgeons and nurses, as well as the uncleanliness of their environment during traditional male circumcision procedures, could expose initiates to infections and morbidity. Environmental health officers should regularly supervise traditional surgeons and nurses in order to prevent the adverse health outcomes associated with the traditional male circumcision practice.
- Full Text:
- Date Issued: 2019
- Authors: Dalasa, Siyamthemba
- Date: 2019
- Subjects: Circumcision -- Social aspects
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10353/17029 , vital:40834
- Description: BACKGROUND Despite the adverse outcomes associated with traditional male circumcision, the practice remains prevalent, especially in the Eastern Cape, South, Africa. This study seeks to assess the practices of traditional surgeons and nurses in relation to the prevention and control of infections and their understanding of human physiological mechanisms during circumcision processes. METHOD This study has adopted a qualitative design, which involved conducting 115 semistructured interviews among traditional surgeons, traditional nurses and traditionally circumcised men, and one focus group discussion among traditional nurses. The data generated were transcribed and subjected to thematic content analysis. RESULTS The analysis revealed that both traditional surgeons and nurses demonstrated both poor aseptic techniques and a lack of knowledge of how the human body functions. Their lack of knowledge of basic human physiology meant that they trivialised sepsis in the penile wound. In addition, the seclusion lodges for circumcision and initiates living were unclean and uninhabitable. CONCLUSION The poor aseptic techniques of traditional surgeons and nurses, as well as the uncleanliness of their environment during traditional male circumcision procedures, could expose initiates to infections and morbidity. Environmental health officers should regularly supervise traditional surgeons and nurses in order to prevent the adverse health outcomes associated with the traditional male circumcision practice.
- Full Text:
- Date Issued: 2019
Registered nurses' experiences of working with patients diagnosed with substance-induced psychosis in a tertiary psychiatric hospital
- Authors: Damane, Brenda
- Date: 2019
- Subjects: Psychiatric nursing , Psychiatry Psychoses -- Treatment Substance abuse -- Treatment -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/39457 , vital:35250
- Description: Illicit drug use is common among patients with mental health difficulties. Illicit drug use is common among patients with mental health difficulties. Psychiatric inpatient services often must provide care for people with mental health difficulties who use prohibited drugs. Admissions to an acute care hospital in the Eastern Cape are done daily, with as many as eight admissions per day. Statistics show that a significant percentage of these admissions are of patients with substance-induced psychosis. These patients are acutely mentally ill and may present with symptoms such as hearing voices, delusions, verbal, or physical aggression where they attack staff and other patients and being restless. Patients with a diagnosis of substance-induced psychosis are difficult to take care of due to their behaviour associated with the above symptoms. These patients are also young and because they are psychotic, they make the acute wards unruly, making it difficult to nurse them. The following research question arises from the above-mentioned problem: What are the experiences of registered nurses working in a tertiary psychiatric hospital with patients admitted with a diagnosis of substance-induced psychosis? The goal of this study is to explore and describe the experiences of registered nurses working in a tertiary psychiatric hospital when caring for patients admitted with substance-induced psychosis. The researcher used a qualitative, exploratory, descriptive, and contextual design. The research population consisted of registered nurses working at a tertiary psychiatric hospital. Purposive sampling was used to identify participants. Data was collected by means of one-to-one interviews and field notes. Data was analysed using Tesch’s model of content analysis to reduce the information to themes or categories. The researcher used Guba’s model of trustworthiness to evaluate the study’s rigour. The researcher also used the three fundamental ethical principles which include: the principle of respect for persons, the principle of beneficence and non-maleficence, and the principle of justice to guide the researcher during the research process. Four main themes with subthemes emerged from the study. The study showed that registered nurses working in a psychiatric hospital found it difficult to nurse patients with substance-induced psychosis. These difficulties included the characteristics these patients presented with, the ward not being conducive to nursing substanceinduced psychotic patients, which resulted in registered nurses feeling emotionally drained when nursing these patients. Recommendations were made as an effort to help registered nurses cope better in caring for substance-induced psychotic patients and prevent staff from experiencing burnout.
- Full Text:
- Date Issued: 2019
- Authors: Damane, Brenda
- Date: 2019
- Subjects: Psychiatric nursing , Psychiatry Psychoses -- Treatment Substance abuse -- Treatment -- South Africa -- Eastern Cape
- Language: English
- Type: Thesis , Masters , MCur
- Identifier: http://hdl.handle.net/10948/39457 , vital:35250
- Description: Illicit drug use is common among patients with mental health difficulties. Illicit drug use is common among patients with mental health difficulties. Psychiatric inpatient services often must provide care for people with mental health difficulties who use prohibited drugs. Admissions to an acute care hospital in the Eastern Cape are done daily, with as many as eight admissions per day. Statistics show that a significant percentage of these admissions are of patients with substance-induced psychosis. These patients are acutely mentally ill and may present with symptoms such as hearing voices, delusions, verbal, or physical aggression where they attack staff and other patients and being restless. Patients with a diagnosis of substance-induced psychosis are difficult to take care of due to their behaviour associated with the above symptoms. These patients are also young and because they are psychotic, they make the acute wards unruly, making it difficult to nurse them. The following research question arises from the above-mentioned problem: What are the experiences of registered nurses working in a tertiary psychiatric hospital with patients admitted with a diagnosis of substance-induced psychosis? The goal of this study is to explore and describe the experiences of registered nurses working in a tertiary psychiatric hospital when caring for patients admitted with substance-induced psychosis. The researcher used a qualitative, exploratory, descriptive, and contextual design. The research population consisted of registered nurses working at a tertiary psychiatric hospital. Purposive sampling was used to identify participants. Data was collected by means of one-to-one interviews and field notes. Data was analysed using Tesch’s model of content analysis to reduce the information to themes or categories. The researcher used Guba’s model of trustworthiness to evaluate the study’s rigour. The researcher also used the three fundamental ethical principles which include: the principle of respect for persons, the principle of beneficence and non-maleficence, and the principle of justice to guide the researcher during the research process. Four main themes with subthemes emerged from the study. The study showed that registered nurses working in a psychiatric hospital found it difficult to nurse patients with substance-induced psychosis. These difficulties included the characteristics these patients presented with, the ward not being conducive to nursing substanceinduced psychotic patients, which resulted in registered nurses feeling emotionally drained when nursing these patients. Recommendations were made as an effort to help registered nurses cope better in caring for substance-induced psychotic patients and prevent staff from experiencing burnout.
- Full Text:
- Date Issued: 2019
Happiness in the South African construction industry
- Authors: Damba, Wayne
- Date: 2019
- Subjects: Happiness , Work -- Psychological aspects Psychology, Industrial Construction industry -- Psychological aspects Construction workers -- Psychological aspects
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/38068 , vital:34313
- Description: Studies on Happiness, commonly referred to as Subjective Wellbeing studies, have gained much attention in the past few years. Happiness has been measured from a national level to specific areas or industry. Happiness generally refers to the positive state of wellbeing. Happiness has a positive effect on individuals and society at large. Research has shown that happy employees are purpose driven and productive. They are self-motivated and influence other employees positively. Happiness contributes significantly to economic growth and development. This has resulted in countries and many large institutions being interested in the happiness levels of the citizens and employees. This study focuses on Happiness in the South African Construction industry. South Africa is a developing country; thus, there are many infrastructure development projects. The construction industry is an important industry in the South African economy because of its contribution to employment and infrastructure development. Improving the happiness levels of the construction workers will improve the quality of work produced in the industry as well as reduce the costs that are associated with unproductive employees. Happy employees are innovative and engaged in work. The primary data were collected from a Construction Company in Cape Town. The Questionnaire was developed from the literature on happiness studies. Questionnaires were printed from Question Pro and circulated to the employees. 165 employees successfully completed the survey. A conceptual model was developed and exploratory factor analysis was used to test the model. The results indicate that influence in the workplace, workplace relationships, satisfaction with work-life balance, purpose, optimism, work satisfaction, leisure, SA Pride and trust were some of the variables which positively influences Happiness in the construction industry. The results of this study further indicate that South African construction workers are generally happy. Construction workers generally do not trust the government and management.
- Full Text:
- Date Issued: 2019
- Authors: Damba, Wayne
- Date: 2019
- Subjects: Happiness , Work -- Psychological aspects Psychology, Industrial Construction industry -- Psychological aspects Construction workers -- Psychological aspects
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/38068 , vital:34313
- Description: Studies on Happiness, commonly referred to as Subjective Wellbeing studies, have gained much attention in the past few years. Happiness has been measured from a national level to specific areas or industry. Happiness generally refers to the positive state of wellbeing. Happiness has a positive effect on individuals and society at large. Research has shown that happy employees are purpose driven and productive. They are self-motivated and influence other employees positively. Happiness contributes significantly to economic growth and development. This has resulted in countries and many large institutions being interested in the happiness levels of the citizens and employees. This study focuses on Happiness in the South African Construction industry. South Africa is a developing country; thus, there are many infrastructure development projects. The construction industry is an important industry in the South African economy because of its contribution to employment and infrastructure development. Improving the happiness levels of the construction workers will improve the quality of work produced in the industry as well as reduce the costs that are associated with unproductive employees. Happy employees are innovative and engaged in work. The primary data were collected from a Construction Company in Cape Town. The Questionnaire was developed from the literature on happiness studies. Questionnaires were printed from Question Pro and circulated to the employees. 165 employees successfully completed the survey. A conceptual model was developed and exploratory factor analysis was used to test the model. The results indicate that influence in the workplace, workplace relationships, satisfaction with work-life balance, purpose, optimism, work satisfaction, leisure, SA Pride and trust were some of the variables which positively influences Happiness in the construction industry. The results of this study further indicate that South African construction workers are generally happy. Construction workers generally do not trust the government and management.
- Full Text:
- Date Issued: 2019
Teachers’ perception of the integration of environmental education into grade 12 curriculum in East London Education District
- Authors: Damoah, Benjamin
- Date: 2019
- Subjects: Environmental education
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10353/16528 , vital:40728
- Description: The study focuses on teachers’ perception of the integration of environmental education into grade 12 curriculum in East London education district. This study is based on empirical research. The theoretical framework of the study is based on Opportunity to Learn (OTL). The concept of OTL was formulated by international Association of Achievements (McDonnell, 1995).OTL is multiplicity of factors that create the conditions for teaching and learning, such as curricula, learning materials, facilities, teachers and instructional experiences. The research study is supported by national and international literatures based on environmental education and integration of environmental education as a component in the school curriculum, and policy documents. The study adopted qualitative research approach, using phenomenological method and interpretivism paradigm respectively. The empirical data was collected from one high school in Mdantsane Township in East London education district. The study sample consisted of 6 high school teachers. Data was collected through semi- structured interviews. According to the findings of the research, grade 12 teachers expressed disparities in their perceptions of environmental education as an integrated component into their subjects. Most of the subject teachers focused on the aspect of knowledge acquisition. According to South African education system, environmental education (EE) has been integrated into all subjects. Although there is environmental education in the GET and FET phase curriculum respectively, however it is not integrated evenly in all subjects. Some subjects like Life sciences, geography have more environmental content than other subjects. Teachers suggested that the approach adopted to integrate environmental education into the school curriculum was not favourable because teachers claimed that what is to be taught as environmental education in the various subjects is not indicated explicitly in the CAPS document. The CAPS document prescribes EE integration into all subjects which makes the teaching of EE a collective responsibility. The main actors of EE integration implementation are themselves a constraint to the success of the integration. The teacher is confronted with many challenges in the process of environmental education integration. This includes lack of teaching and learning resources, time and large class size. The role of teachers in the implementation of environmental education in developing an environmentally literate citizenry is of great significance. The responsibility of the government in ii developing a curriculum with clear goals and content, developing teachers’ capacity in the teaching of environmental education and provision of teaching and learning materials needs to be taken seriously by the government in educational plans and programs. Topics for future research on the integration of EE into grade 12 curriculums were suggested in order to improve on teaching and learning of environmental education
- Full Text:
- Date Issued: 2019
- Authors: Damoah, Benjamin
- Date: 2019
- Subjects: Environmental education
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10353/16528 , vital:40728
- Description: The study focuses on teachers’ perception of the integration of environmental education into grade 12 curriculum in East London education district. This study is based on empirical research. The theoretical framework of the study is based on Opportunity to Learn (OTL). The concept of OTL was formulated by international Association of Achievements (McDonnell, 1995).OTL is multiplicity of factors that create the conditions for teaching and learning, such as curricula, learning materials, facilities, teachers and instructional experiences. The research study is supported by national and international literatures based on environmental education and integration of environmental education as a component in the school curriculum, and policy documents. The study adopted qualitative research approach, using phenomenological method and interpretivism paradigm respectively. The empirical data was collected from one high school in Mdantsane Township in East London education district. The study sample consisted of 6 high school teachers. Data was collected through semi- structured interviews. According to the findings of the research, grade 12 teachers expressed disparities in their perceptions of environmental education as an integrated component into their subjects. Most of the subject teachers focused on the aspect of knowledge acquisition. According to South African education system, environmental education (EE) has been integrated into all subjects. Although there is environmental education in the GET and FET phase curriculum respectively, however it is not integrated evenly in all subjects. Some subjects like Life sciences, geography have more environmental content than other subjects. Teachers suggested that the approach adopted to integrate environmental education into the school curriculum was not favourable because teachers claimed that what is to be taught as environmental education in the various subjects is not indicated explicitly in the CAPS document. The CAPS document prescribes EE integration into all subjects which makes the teaching of EE a collective responsibility. The main actors of EE integration implementation are themselves a constraint to the success of the integration. The teacher is confronted with many challenges in the process of environmental education integration. This includes lack of teaching and learning resources, time and large class size. The role of teachers in the implementation of environmental education in developing an environmentally literate citizenry is of great significance. The responsibility of the government in ii developing a curriculum with clear goals and content, developing teachers’ capacity in the teaching of environmental education and provision of teaching and learning materials needs to be taken seriously by the government in educational plans and programs. Topics for future research on the integration of EE into grade 12 curriculums were suggested in order to improve on teaching and learning of environmental education
- Full Text:
- Date Issued: 2019
A critical analysis of the South African government's approach to social cohesion
- Authors: Daniels, Lorna
- Date: 2019
- Subjects: Social integration , Social participation Economics -- Sociological aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/38079 , vital:34315
- Description: The work of scholars and government programme have in the last decade or more paid a considerable amount of attention to the issue of fostering social cohesion under conditions on the increase rate of community- level upheavals and localized conflict. While some studies critique the South African government’s social cohesion strategy of 2012 in the main, others seek to identify its measurements and develop barometers to track its progress.
- Full Text: false
- Date Issued: 2019
- Authors: Daniels, Lorna
- Date: 2019
- Subjects: Social integration , Social participation Economics -- Sociological aspects
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/38079 , vital:34315
- Description: The work of scholars and government programme have in the last decade or more paid a considerable amount of attention to the issue of fostering social cohesion under conditions on the increase rate of community- level upheavals and localized conflict. While some studies critique the South African government’s social cohesion strategy of 2012 in the main, others seek to identify its measurements and develop barometers to track its progress.
- Full Text: false
- Date Issued: 2019
Pyramidal deliberative democracy
- Authors: Danielsen, James
- Date: 2019
- Subjects: Democracy , Information technology -- Political aspects , Internet in public administration , Political participation -- Computer network resources , World politics
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/74502 , vital:30309
- Description: This dissertation has two main objectives. First, to outline an ICT-facilitated model of democracy called ‘pyramidal democracy’ that reconciles deliberative democracy with mass engagement. Second, to suggest how this model of democracy might engender the democratisation of the global economy and thus the provision of a basic level of economic security for all global citizens. At the core of the model is the pyramidal deliberative network, a means of organising citizens into small online deliberative groups and linking these groups together by means of an iterative process of delegate-selection and group-formation. The pyramidal network enables citizens to aggregate their preferences in a deliberative manner, and then project social power by authorizing the delegates at the top-tier of the pyramidal network to communicate their social demands to elected officials or to other points of authority. The envisioned outcome is the democratisation of the public sphere by means of the proliferation of deliberative networks in the government, market, and civil society spheres. Transnational pyramidal networks may make it feasible to instantiate a new citizen-based schema of global governance and, thereby, facilitate the reform of the United Nations and enable a transition towards global peace, sustainability, and distributive justice. Distributive justice might be achieved by means of implementing the six components of a democratised economy: participatory budgeting, fee-and-dividend taxes, a basic income, monetary reform, workplace democracy, and the sharing economy. Taken together, these components might enable the universal provision of a social minimum – a universal basic income sufficient for basic security and real freedom. Taken to its logical conclusion, a democratised economy may also enable a transition towards a post-scarcity economic order characterised by a maximal stock of humanmade and natural capital that would not exceed the sustainable carrying capacity of the earth.
- Full Text:
- Date Issued: 2019
- Authors: Danielsen, James
- Date: 2019
- Subjects: Democracy , Information technology -- Political aspects , Internet in public administration , Political participation -- Computer network resources , World politics
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/74502 , vital:30309
- Description: This dissertation has two main objectives. First, to outline an ICT-facilitated model of democracy called ‘pyramidal democracy’ that reconciles deliberative democracy with mass engagement. Second, to suggest how this model of democracy might engender the democratisation of the global economy and thus the provision of a basic level of economic security for all global citizens. At the core of the model is the pyramidal deliberative network, a means of organising citizens into small online deliberative groups and linking these groups together by means of an iterative process of delegate-selection and group-formation. The pyramidal network enables citizens to aggregate their preferences in a deliberative manner, and then project social power by authorizing the delegates at the top-tier of the pyramidal network to communicate their social demands to elected officials or to other points of authority. The envisioned outcome is the democratisation of the public sphere by means of the proliferation of deliberative networks in the government, market, and civil society spheres. Transnational pyramidal networks may make it feasible to instantiate a new citizen-based schema of global governance and, thereby, facilitate the reform of the United Nations and enable a transition towards global peace, sustainability, and distributive justice. Distributive justice might be achieved by means of implementing the six components of a democratised economy: participatory budgeting, fee-and-dividend taxes, a basic income, monetary reform, workplace democracy, and the sharing economy. Taken together, these components might enable the universal provision of a social minimum – a universal basic income sufficient for basic security and real freedom. Taken to its logical conclusion, a democratised economy may also enable a transition towards a post-scarcity economic order characterised by a maximal stock of humanmade and natural capital that would not exceed the sustainable carrying capacity of the earth.
- Full Text:
- Date Issued: 2019
The nexus between capital inflows and credit growth in South Africa
- Authors: Davani, Siviwe
- Date: 2019
- Subjects: Capital movements Credit
- Language: English
- Type: Thesis , Masters , MCom (Economics)
- Identifier: http://hdl.handle.net/10353/16885 , vital:40782
- Description: This study examines the effect of capital inflows on credit growth on the South African economy. Capital inflows ease the constraint of the low domestic savings in the domestic economy. The study employed the Structural Vector Auto Regression model to analyse the relationship between the variables of interest. The findings of the study indicate that the two types of capital inflows employed in the study, Foreign Direct Investment and Foreign Portfolio investment have a significant effect on credit growth in the long-run. The results also indicate that there are other important factors such as macroeconomic stability and political stability which have a significant effect of capital inflows into South Africa. Overall, the results revealed that a greater variation of credit growth is explained by GDP. This indicates that there is a link between GDP and FDI and FPI given their link with credit growth. These results also suggest that the foreign capital channel can be another channel which may affect growth in the domestic economy in the event that there are negative innovations which affects capital flows to South Africa. The study thus suggests that policies which ensures macroeconomic stability and political stability should be pursued given their influence on capital inflows into South Africa. Also it’s recommended that the country mobilise domestic resources to ensure sustainable development
- Full Text:
- Date Issued: 2019
- Authors: Davani, Siviwe
- Date: 2019
- Subjects: Capital movements Credit
- Language: English
- Type: Thesis , Masters , MCom (Economics)
- Identifier: http://hdl.handle.net/10353/16885 , vital:40782
- Description: This study examines the effect of capital inflows on credit growth on the South African economy. Capital inflows ease the constraint of the low domestic savings in the domestic economy. The study employed the Structural Vector Auto Regression model to analyse the relationship between the variables of interest. The findings of the study indicate that the two types of capital inflows employed in the study, Foreign Direct Investment and Foreign Portfolio investment have a significant effect on credit growth in the long-run. The results also indicate that there are other important factors such as macroeconomic stability and political stability which have a significant effect of capital inflows into South Africa. Overall, the results revealed that a greater variation of credit growth is explained by GDP. This indicates that there is a link between GDP and FDI and FPI given their link with credit growth. These results also suggest that the foreign capital channel can be another channel which may affect growth in the domestic economy in the event that there are negative innovations which affects capital flows to South Africa. The study thus suggests that policies which ensures macroeconomic stability and political stability should be pursued given their influence on capital inflows into South Africa. Also it’s recommended that the country mobilise domestic resources to ensure sustainable development
- Full Text:
- Date Issued: 2019
The futures of orthopedic implants through 3D printing technology for South Africa
- Authors: Davids, Craig Nolan
- Date: 2019
- Subjects: Medical innovations -- Economic aspects -- South Africa , Three-dimensional printing Three-dimensional imaging Orthopedics
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/39381 , vital:35238
- Description: 3D printing is one of the most disruptive technologies that truly has the potential to change medicine and healthcare by making care affordable, accessible and personalized. It can bring a new era if printers become more sophisticated, printing biomaterials gets safely regulated and the public acquires a common sense about how 3D printing works. An understanding and appreciation of the possible futures of 3D printing technology will be of great value to various stakeholders within the country. This research will identify and describe current drivers that should be appreciated for the government, business communities, academic institutions, healthcare provider’s policy makers and the society at large to make intelligent decisions about the future of 3D printing in medical devices. This study is aimed at identifying the possible futures of 3D printing in orthopaedic devices in South Africa. Causal Layered Analysis (CLA) and the Six Pillars of Futures were identified as the preferred methodologies to be utilised to respond to the research objectives of this study. A detailed literature study was undertaken to evaluate the existing body of knowledge on the research topic. The literature study revealed that several factors needs to be addressed before 3D printing is completely integrated into everyday joint reconstruction surgery. Having already made a big impact in the medical sector, three-dimensional printing (3DP) technology continues to push the boundaries of cost efficiency, convenience, and customization. It has transformed some aspects of medical device production. To date, 3D printing has been employed predominantly by hobbyists, product designers and a few select industrial applications, but the performance of additive manufacturing equipment is quickly evolving, the choice of materials is increasing, and prices of both materials and printers are falling rapidly, all factors through which 3D printing is swiftly progressing to attain wider consumer acceptance and a greater number of manufacturing uses.
- Full Text:
- Date Issued: 2019
- Authors: Davids, Craig Nolan
- Date: 2019
- Subjects: Medical innovations -- Economic aspects -- South Africa , Three-dimensional printing Three-dimensional imaging Orthopedics
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/39381 , vital:35238
- Description: 3D printing is one of the most disruptive technologies that truly has the potential to change medicine and healthcare by making care affordable, accessible and personalized. It can bring a new era if printers become more sophisticated, printing biomaterials gets safely regulated and the public acquires a common sense about how 3D printing works. An understanding and appreciation of the possible futures of 3D printing technology will be of great value to various stakeholders within the country. This research will identify and describe current drivers that should be appreciated for the government, business communities, academic institutions, healthcare provider’s policy makers and the society at large to make intelligent decisions about the future of 3D printing in medical devices. This study is aimed at identifying the possible futures of 3D printing in orthopaedic devices in South Africa. Causal Layered Analysis (CLA) and the Six Pillars of Futures were identified as the preferred methodologies to be utilised to respond to the research objectives of this study. A detailed literature study was undertaken to evaluate the existing body of knowledge on the research topic. The literature study revealed that several factors needs to be addressed before 3D printing is completely integrated into everyday joint reconstruction surgery. Having already made a big impact in the medical sector, three-dimensional printing (3DP) technology continues to push the boundaries of cost efficiency, convenience, and customization. It has transformed some aspects of medical device production. To date, 3D printing has been employed predominantly by hobbyists, product designers and a few select industrial applications, but the performance of additive manufacturing equipment is quickly evolving, the choice of materials is increasing, and prices of both materials and printers are falling rapidly, all factors through which 3D printing is swiftly progressing to attain wider consumer acceptance and a greater number of manufacturing uses.
- Full Text:
- Date Issued: 2019
Categorising Network Telescope data using big data enrichment techniques
- Authors: Davis, Michael Reginald
- Date: 2019
- Subjects: Denial of service attacks , Big data , Computer networks -- Security measures
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/92941 , vital:30766
- Description: Network Telescopes, Internet backbone sampling, IDS and other forms of network-sourced Threat Intelligence provide researchers with insight into the methods and intent of remote entities by capturing network traffic and analysing the resulting data. This analysis and determination of intent is made difficult by the large amounts of potentially malicious traffic, coupled with limited amount of knowledge that can be attributed to the source of the incoming data, as the source is known only by its IP address. Due to the lack of commonly available tooling, many researchers start this analysis from the beginning and so repeat and re-iterate previous research as the bulk of their work. As a result new insight into methods and approaches of analysis is gained at a high cost. Our research approaches this problem by using additional knowledge about the source IP address such as open ports, reverse and forward DNS, BGP routing tables and more, to enhance the researcher's ability to understand the traffic source. The research is a BigData experiment, where large (hundreds of GB) datasets are merged with a two month section of Network Telescope data using a set of Python scripts. The result are written to a Google BigQuery database table. Analysis of the network data is greatly simplified, with questions about the nature of the source, such as its device class (home routing device or server), potential vulnerabilities (open telnet ports or databases) and location becoming relatively easy to answer. Using this approach, researchers can focus on the questions that need answering and efficiently address them. This research could be taken further by using additional data sources such as Geo-location, WHOIS lookups, Threat Intelligence feeds and many others. Other potential areas of research include real-time categorisation of incoming packets, in order to better inform alerting and reporting systems' configuration. In conclusion, categorising Network Telescope data in this way provides insight into the intent of the (apparent) originator and as such is a valuable tool for those seeking to understand the purpose and intent of arriving packets. In particular, the ability to remove packets categorised as non-malicious (e.g. those in the Research category) from the data eliminates a known source of `noise' from the data. This allows the researcher to focus their efforts in a more productive manner.
- Full Text:
- Date Issued: 2019
- Authors: Davis, Michael Reginald
- Date: 2019
- Subjects: Denial of service attacks , Big data , Computer networks -- Security measures
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/92941 , vital:30766
- Description: Network Telescopes, Internet backbone sampling, IDS and other forms of network-sourced Threat Intelligence provide researchers with insight into the methods and intent of remote entities by capturing network traffic and analysing the resulting data. This analysis and determination of intent is made difficult by the large amounts of potentially malicious traffic, coupled with limited amount of knowledge that can be attributed to the source of the incoming data, as the source is known only by its IP address. Due to the lack of commonly available tooling, many researchers start this analysis from the beginning and so repeat and re-iterate previous research as the bulk of their work. As a result new insight into methods and approaches of analysis is gained at a high cost. Our research approaches this problem by using additional knowledge about the source IP address such as open ports, reverse and forward DNS, BGP routing tables and more, to enhance the researcher's ability to understand the traffic source. The research is a BigData experiment, where large (hundreds of GB) datasets are merged with a two month section of Network Telescope data using a set of Python scripts. The result are written to a Google BigQuery database table. Analysis of the network data is greatly simplified, with questions about the nature of the source, such as its device class (home routing device or server), potential vulnerabilities (open telnet ports or databases) and location becoming relatively easy to answer. Using this approach, researchers can focus on the questions that need answering and efficiently address them. This research could be taken further by using additional data sources such as Geo-location, WHOIS lookups, Threat Intelligence feeds and many others. Other potential areas of research include real-time categorisation of incoming packets, in order to better inform alerting and reporting systems' configuration. In conclusion, categorising Network Telescope data in this way provides insight into the intent of the (apparent) originator and as such is a valuable tool for those seeking to understand the purpose and intent of arriving packets. In particular, the ability to remove packets categorised as non-malicious (e.g. those in the Research category) from the data eliminates a known source of `noise' from the data. This allows the researcher to focus their efforts in a more productive manner.
- Full Text:
- Date Issued: 2019
Modelling the structure and interactions of leukocyte integrins
- Authors: Dawson, Kyle-Richard
- Date: 2019
- Subjects: Proteins -- Structure , Molecular immunology Biochemistry
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/39392 , vital:35239
- Description: Heterodimeric transmembrane protein structure is complex and insufficient structural information exists, concerning leukocyte integrin proteins. To determine protein structure, homology modelling was conducted and modelling software was evaluated. Leukocyte integrin homologs were obtained from the PDB and models were generated using online servers and MODELLER. Template homologs were fewer in number and of lower quality in comparison to monomeric extracellular proteins. Models were docked using ClusPro, HADDOCK2.2 and AutoDock vina. Models were evaluated using PROSA, Verify-3D and PROSESS. Higher quality models were generated when using MODELLER to separately model monomeric subunits in three defined domain regions (extracellular, transmembrane and cytoplasmic). Template selection concerning these proteins is critical as an intricate relationship exists between model quality, template quality, template quantity, template resolution, target-template identity and template sequence coverage. Docking monomeric subunits was challenging when using ClusPro and the best ligand docking procedures were completed using AutoDock vina. PROSESS provided the most accurate evaluation of protein models, in comparison to PROSA and Verify-3D. These results indicate that although homology modelling is a powerful tool there is much room for improvement. Experimentally obtained templates should be expanded upon within the PDB and energy functions should cater for both monomeric and transmembrane heterodimeric proteins. Leukocyte integrins appear to adopt a closed conformation, which may still facilitate LDV ligand association within the α/β interface. The α3β1 integrin may interact with laminin-5 through the ELV sequence within the G-domain of the α laminin subunit
- Full Text:
- Date Issued: 2019
- Authors: Dawson, Kyle-Richard
- Date: 2019
- Subjects: Proteins -- Structure , Molecular immunology Biochemistry
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10948/39392 , vital:35239
- Description: Heterodimeric transmembrane protein structure is complex and insufficient structural information exists, concerning leukocyte integrin proteins. To determine protein structure, homology modelling was conducted and modelling software was evaluated. Leukocyte integrin homologs were obtained from the PDB and models were generated using online servers and MODELLER. Template homologs were fewer in number and of lower quality in comparison to monomeric extracellular proteins. Models were docked using ClusPro, HADDOCK2.2 and AutoDock vina. Models were evaluated using PROSA, Verify-3D and PROSESS. Higher quality models were generated when using MODELLER to separately model monomeric subunits in three defined domain regions (extracellular, transmembrane and cytoplasmic). Template selection concerning these proteins is critical as an intricate relationship exists between model quality, template quality, template quantity, template resolution, target-template identity and template sequence coverage. Docking monomeric subunits was challenging when using ClusPro and the best ligand docking procedures were completed using AutoDock vina. PROSESS provided the most accurate evaluation of protein models, in comparison to PROSA and Verify-3D. These results indicate that although homology modelling is a powerful tool there is much room for improvement. Experimentally obtained templates should be expanded upon within the PDB and energy functions should cater for both monomeric and transmembrane heterodimeric proteins. Leukocyte integrins appear to adopt a closed conformation, which may still facilitate LDV ligand association within the α/β interface. The α3β1 integrin may interact with laminin-5 through the ELV sequence within the G-domain of the α laminin subunit
- Full Text:
- Date Issued: 2019