Checklist, endemism, English vernacular names and identification of the cicadas (Insecta, Hemiptera, Cicadidae) of KwaZulu-Natal, South Africa:
- Armstrong, Adrian J, Villet, Martin H
- Authors: Armstrong, Adrian J , Villet, Martin H
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140586 , vital:37901 , DOI: 10.3897/afrinvertebr.60.35130
- Description: Public understanding of the goals of applied biology and conservation is promoted by showcasing charismatic or significant organisms using vernacular names. Conservation activities in the province of KwaZulu-Natal, South Africa, are prioritising taxa that have high rates of provincial endemism, such as snails, earthworms, millipedes and cicadas. To assist wider public engagement in these activities, an assessment of endemism of the cicadas of KwaZulu-Natal is presented along with a dichotomous, 37-couplet key for the identification of males, based mainly on externally visible morphology and colouration. Standardised English vernacular names coined following a simple naming convention are proposed. Forty-two percent (16 out of 38) of the cicada species known from KwaZulu-Natal are endemic to the province. Photographs of some of the species are included to facilitate their identification. Photographs can be used for identification of various species providing that the diagnostic characters are visible in the photographs. For this purpose, photographs may have to be taken of hand-held individuals. Some of the endemic species are of particular concern for conservation because they are not known to occur in statutory protected areas or are only known from relatively small protected areas. The latter may not be able to ensure the long-term survival of the species. The rate and extent of loss of habitat outside protected areas is likely to be a grave threat to species that are not protected or that are inadequately conserved in statutory protected areas. The standardised vernacular names proposed here provide a tool for communicating provincial conservation plans and concerns with stakeholders in KwaZulu-Natal and for stimulating interest in cicadas amongst land users, environmental impact assessment practitioners, biologists, naturalists and citizen scientists.
- Full Text:
- Date Issued: 2019
- Authors: Armstrong, Adrian J , Villet, Martin H
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140586 , vital:37901 , DOI: 10.3897/afrinvertebr.60.35130
- Description: Public understanding of the goals of applied biology and conservation is promoted by showcasing charismatic or significant organisms using vernacular names. Conservation activities in the province of KwaZulu-Natal, South Africa, are prioritising taxa that have high rates of provincial endemism, such as snails, earthworms, millipedes and cicadas. To assist wider public engagement in these activities, an assessment of endemism of the cicadas of KwaZulu-Natal is presented along with a dichotomous, 37-couplet key for the identification of males, based mainly on externally visible morphology and colouration. Standardised English vernacular names coined following a simple naming convention are proposed. Forty-two percent (16 out of 38) of the cicada species known from KwaZulu-Natal are endemic to the province. Photographs of some of the species are included to facilitate their identification. Photographs can be used for identification of various species providing that the diagnostic characters are visible in the photographs. For this purpose, photographs may have to be taken of hand-held individuals. Some of the endemic species are of particular concern for conservation because they are not known to occur in statutory protected areas or are only known from relatively small protected areas. The latter may not be able to ensure the long-term survival of the species. The rate and extent of loss of habitat outside protected areas is likely to be a grave threat to species that are not protected or that are inadequately conserved in statutory protected areas. The standardised vernacular names proposed here provide a tool for communicating provincial conservation plans and concerns with stakeholders in KwaZulu-Natal and for stimulating interest in cicadas amongst land users, environmental impact assessment practitioners, biologists, naturalists and citizen scientists.
- Full Text:
- Date Issued: 2019
Learning to learn: a critical realist exploration into the home established learning practices of a marginalised community in Port Elizabeth
- Authors: Armstrong, Meredith
- Date: 2019
- Subjects: Minorities -- Education (Higher) -- South Africa , Readiness for school -- Social aspects -- South Africa , Inclusive education -- Social aspects -- South Africa , Marginality, Social -- South Africa , Critical realism
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/93778 , vital:30939
- Description: This study was completed as part of a project exploring social inclusion and exclusion in South African higher education. In a globalised world, the achievement of a qualification from an institution of higher education is increasingly key to finding any sort of employment. This is particularly the case in South Africa where employment amongst black citizens is inordinately high. The aim of the research reported upon in this thesis was to better understand the construct of ‘epistemological access’ (Morrow, 1992), often used in relation to the needs of black working class students entering higher education, in relation to performance data (see for example, CHE, 2016) that repeatedly shows that black students fare less well than their white peers. Following what might be termed a ‘social’ approach to understanding access, this study begins long before most students have even heard of higher education and focuses on identifying the mechanisms that come into play at much earlier level of learning and literacy development. The study outlines the development of ‘ways of being’, or social practices, surrounding learning in a marginalised community in Port Elizabeth, in the Eastern Cape, South Africa. This was achieved by means of critical ethnography and it is therefore qualitatively based. The study shows how social structures enable or constrain a child’s school readiness and how they then go on to support or impede progress in school where the language and literacy needed for educational success are further developed. The study therefore aims to allow us to explain global data indicating that the single greatest indicator of a young person’s ability to access and succeed in higher education is the level of education of caregivers in their homes of origin. Examined from a critical perspective (i.e. with a concern for social justice), this study has made use of a framework using social, psychological and linguistic theory and more, particularly, the work of sociologist Margaret Archer (1995, 1996, 2003). The study makes particular use of Archer’s ‘morphogenetic framework’ which allows for an analysis of the way structure and culture impact on a child’s development over time. As I was concerned that my own social status might impact on the understandings I developed as a critical ethnographer, the study acknowledges my own experiences of learning and the way my own family sought to enhance them as enabling. In doing this, the study aims to better contribute to understandings of social justice in South Africa.
- Full Text:
- Date Issued: 2019
- Authors: Armstrong, Meredith
- Date: 2019
- Subjects: Minorities -- Education (Higher) -- South Africa , Readiness for school -- Social aspects -- South Africa , Inclusive education -- Social aspects -- South Africa , Marginality, Social -- South Africa , Critical realism
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/93778 , vital:30939
- Description: This study was completed as part of a project exploring social inclusion and exclusion in South African higher education. In a globalised world, the achievement of a qualification from an institution of higher education is increasingly key to finding any sort of employment. This is particularly the case in South Africa where employment amongst black citizens is inordinately high. The aim of the research reported upon in this thesis was to better understand the construct of ‘epistemological access’ (Morrow, 1992), often used in relation to the needs of black working class students entering higher education, in relation to performance data (see for example, CHE, 2016) that repeatedly shows that black students fare less well than their white peers. Following what might be termed a ‘social’ approach to understanding access, this study begins long before most students have even heard of higher education and focuses on identifying the mechanisms that come into play at much earlier level of learning and literacy development. The study outlines the development of ‘ways of being’, or social practices, surrounding learning in a marginalised community in Port Elizabeth, in the Eastern Cape, South Africa. This was achieved by means of critical ethnography and it is therefore qualitatively based. The study shows how social structures enable or constrain a child’s school readiness and how they then go on to support or impede progress in school where the language and literacy needed for educational success are further developed. The study therefore aims to allow us to explain global data indicating that the single greatest indicator of a young person’s ability to access and succeed in higher education is the level of education of caregivers in their homes of origin. Examined from a critical perspective (i.e. with a concern for social justice), this study has made use of a framework using social, psychological and linguistic theory and more, particularly, the work of sociologist Margaret Archer (1995, 1996, 2003). The study makes particular use of Archer’s ‘morphogenetic framework’ which allows for an analysis of the way structure and culture impact on a child’s development over time. As I was concerned that my own social status might impact on the understandings I developed as a critical ethnographer, the study acknowledges my own experiences of learning and the way my own family sought to enhance them as enabling. In doing this, the study aims to better contribute to understandings of social justice in South Africa.
- Full Text:
- Date Issued: 2019
An analysis of the availability of and access to credit from the formal financial sector and the performance of SMEs
- Authors: Asah, Francis Tangwo
- Date: 2019
- Subjects: Small business -- South Africa -- Finance , Microfinance -- South Africa , South Africa -- Economic conditions -- 1991-
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/115138 , vital:34081
- Description: As a developing nation, South Africa faces a high rate of poverty, high levels of inequality in terms of income and a high rate of unemployment. It is officially estimated that about 27.2% of the economically active population are unemployed. SMEs are expected to be an important vehicle to address the challenges of job creation, sustainable economic growth, equitable distribution of income and the overall stimulation of economic development. SMEs in South Africa constitute 99% of all businesses, contributing to employment, income inequality and poverty alleviation (Statistic South Africa, 2018). However, despite the remarkable contribution of SMEs to the economy of South Africa, the failure rate of SMEs (at 75%) is the highest of all the efficiency-driven economies sampled by the Global Entrepreneurship Monitor (GEM). The World Bank affirm that the availability of and access to credit from the formal financial sector is the primary cause of the high failure rate of SMEs. Contemporary literature advance that the future survival and performance of SMEs in South Africa is pegged onto the amount of financial capital available to address their capital needs. Thus, this study sought to analyse the availability of and access to credit from the formal financial sector and the performance of SMEs from the supply and demand-side. In order to achieve the objectives of the study, a sequential exploratory mixed method research design, located in the pragmatic research paradigm, was used in a two phased approach. The qualitative data collection and analysis in Phase 1 informed the quantitative data collection and analysis Phase 2. In Phase 1, in-depth face-to-face semi-structured interviews were conducted with 8 credit and 8 business managers representing the sampling unit of selected formal financial institutions. The qualitative data collected was analysed using the five-steps process of content analysis as illustrated by Terre Blanche et al. (2006:322-326). The main findings with regard to factors that impact on the willingness of the formal financial sector to provide credit to SMEs were collateral, annual business turnover, audited financial records, relationship with the bank, credit profile, nature of the business, economic climate, ethics, nationality, government policy, management team, valid Identity Document/permit, equity contribution, entrepreneurship education, product quality, and business intelligence. Assessing credit applications from SMEs, risk assessment, inspection of financial records, proper documentation and background checks were the different tasks performed by credit and business managers. In addition, the main challenges faced by the formal financial sector in assessing and approving credit in favour of SMEs included the following: lack of investment capital; lack of collateral; lack of proper financial records; poor managerial knowledge; poor business plan; lack of industrial knowledge; and poor legal and credit laws. Lastly, contrary to the notion that formal financial institutions are not interested in investing in SMEs, on average, 70% of SMEs that applied for credit received such credit. In Phase 2, a self-administered questionnaire was used to collect data from formal sector owner/managers of SMEs in the city of Johannesburg. Of the 702 questionnaires distributed, 300 were returned and useable. Data was analysed using the Statistical Package for the Social Sciences (version 24). A test for normality was performed using Shapiro–Wilks test. Reliability was tested using the Cronbach’s Alpha Coefficient. Exploratory factor analysis tested the validity of factors that prevent formal financial sector from granting credit to SMEs while Binary logistic regression was used to infer on the hypotheses. Spearman’s Rho correlation analysis was used to determine whether there was any significant relationship with factors that influence access to credit and SMEs performance. The main findings revealed that access to bank finance was the only challenge that showed a significant correlation with performance. In addition, the study revealed that the South African Identity Document and collateral were the most important factors considered when applying for credit from formal financial institutions. With regard to the reasons why formal financial institutions may refuse to grant credit to SMEs, it was revealed that there was no significant positive relationship between lack of business networking and access to credit from the formal financial sector to SMEs. Conversely, the study also revealed a significant positive relationship between collateral, business information, managerial competency, business intelligence, business ethics, entrepreneurship education, legal system and macro-economy and access to credit from the formal financial sector to SMEs. Thus, it was established that there is a significant positive relationship between access to credit from the formal financial sector and the performance of SMEs.
- Full Text:
- Date Issued: 2019
- Authors: Asah, Francis Tangwo
- Date: 2019
- Subjects: Small business -- South Africa -- Finance , Microfinance -- South Africa , South Africa -- Economic conditions -- 1991-
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/115138 , vital:34081
- Description: As a developing nation, South Africa faces a high rate of poverty, high levels of inequality in terms of income and a high rate of unemployment. It is officially estimated that about 27.2% of the economically active population are unemployed. SMEs are expected to be an important vehicle to address the challenges of job creation, sustainable economic growth, equitable distribution of income and the overall stimulation of economic development. SMEs in South Africa constitute 99% of all businesses, contributing to employment, income inequality and poverty alleviation (Statistic South Africa, 2018). However, despite the remarkable contribution of SMEs to the economy of South Africa, the failure rate of SMEs (at 75%) is the highest of all the efficiency-driven economies sampled by the Global Entrepreneurship Monitor (GEM). The World Bank affirm that the availability of and access to credit from the formal financial sector is the primary cause of the high failure rate of SMEs. Contemporary literature advance that the future survival and performance of SMEs in South Africa is pegged onto the amount of financial capital available to address their capital needs. Thus, this study sought to analyse the availability of and access to credit from the formal financial sector and the performance of SMEs from the supply and demand-side. In order to achieve the objectives of the study, a sequential exploratory mixed method research design, located in the pragmatic research paradigm, was used in a two phased approach. The qualitative data collection and analysis in Phase 1 informed the quantitative data collection and analysis Phase 2. In Phase 1, in-depth face-to-face semi-structured interviews were conducted with 8 credit and 8 business managers representing the sampling unit of selected formal financial institutions. The qualitative data collected was analysed using the five-steps process of content analysis as illustrated by Terre Blanche et al. (2006:322-326). The main findings with regard to factors that impact on the willingness of the formal financial sector to provide credit to SMEs were collateral, annual business turnover, audited financial records, relationship with the bank, credit profile, nature of the business, economic climate, ethics, nationality, government policy, management team, valid Identity Document/permit, equity contribution, entrepreneurship education, product quality, and business intelligence. Assessing credit applications from SMEs, risk assessment, inspection of financial records, proper documentation and background checks were the different tasks performed by credit and business managers. In addition, the main challenges faced by the formal financial sector in assessing and approving credit in favour of SMEs included the following: lack of investment capital; lack of collateral; lack of proper financial records; poor managerial knowledge; poor business plan; lack of industrial knowledge; and poor legal and credit laws. Lastly, contrary to the notion that formal financial institutions are not interested in investing in SMEs, on average, 70% of SMEs that applied for credit received such credit. In Phase 2, a self-administered questionnaire was used to collect data from formal sector owner/managers of SMEs in the city of Johannesburg. Of the 702 questionnaires distributed, 300 were returned and useable. Data was analysed using the Statistical Package for the Social Sciences (version 24). A test for normality was performed using Shapiro–Wilks test. Reliability was tested using the Cronbach’s Alpha Coefficient. Exploratory factor analysis tested the validity of factors that prevent formal financial sector from granting credit to SMEs while Binary logistic regression was used to infer on the hypotheses. Spearman’s Rho correlation analysis was used to determine whether there was any significant relationship with factors that influence access to credit and SMEs performance. The main findings revealed that access to bank finance was the only challenge that showed a significant correlation with performance. In addition, the study revealed that the South African Identity Document and collateral were the most important factors considered when applying for credit from formal financial institutions. With regard to the reasons why formal financial institutions may refuse to grant credit to SMEs, it was revealed that there was no significant positive relationship between lack of business networking and access to credit from the formal financial sector to SMEs. Conversely, the study also revealed a significant positive relationship between collateral, business information, managerial competency, business intelligence, business ethics, entrepreneurship education, legal system and macro-economy and access to credit from the formal financial sector to SMEs. Thus, it was established that there is a significant positive relationship between access to credit from the formal financial sector and the performance of SMEs.
- Full Text:
- Date Issued: 2019
Indigenous polycentric and nested customary sea-tenure (CST) institutions: a Solomon Islands case study
- Authors: Aswani, Shankar
- Date: 2019
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/178964 , vital:40100 , ISBN 9780429628283
- Description: In one volume, this book brings together a diversity of approaches, theory and frameworks that can be used to analyse the governance of renewable natural resources. Renewable natural resources are under pressure, with over-exploitation and degradation raising concern globally. Understanding governance systems and practice is essential for developing effective and fair solutions. This book introduces readers to key concepts and issues concerned with the governance of renewable natural resources and illustrates the diversity of approaches, theories and frameworks that have been used to analyse governance systems and practice. Each chapter provides an introduction to an area of literature and theory and demonstrates application through a case study. The book covers a range of geographical locations, with a focus on low- and middle-income countries, and several types of natural resources. The approaches and theories introduced include common property theory, political ecology, institutional analysis, the social -ecological systems framework and social network analysis. Findings from across the chapters support an analytical focus on institutions and local context and a practical focus on diverse, flexible and inclusive governance solutions. The book serves as an essential introduction to the governance of renewable natural resources for students, researchers and practitioners.
- Full Text:
- Date Issued: 2019
- Authors: Aswani, Shankar
- Date: 2019
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/178964 , vital:40100 , ISBN 9780429628283
- Description: In one volume, this book brings together a diversity of approaches, theory and frameworks that can be used to analyse the governance of renewable natural resources. Renewable natural resources are under pressure, with over-exploitation and degradation raising concern globally. Understanding governance systems and practice is essential for developing effective and fair solutions. This book introduces readers to key concepts and issues concerned with the governance of renewable natural resources and illustrates the diversity of approaches, theories and frameworks that have been used to analyse governance systems and practice. Each chapter provides an introduction to an area of literature and theory and demonstrates application through a case study. The book covers a range of geographical locations, with a focus on low- and middle-income countries, and several types of natural resources. The approaches and theories introduced include common property theory, political ecology, institutional analysis, the social -ecological systems framework and social network analysis. Findings from across the chapters support an analytical focus on institutions and local context and a practical focus on diverse, flexible and inclusive governance solutions. The book serves as an essential introduction to the governance of renewable natural resources for students, researchers and practitioners.
- Full Text:
- Date Issued: 2019
Perspectives in coastal human ecology (CHE) for marine conservation
- Authors: Aswani, Shankar
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125576 , vital:35797 , https://doi.10.1016/j.biocon.2019.05.047
- Description: Coastal human ecology (CHE) is a mixture of different theoretical and thematic approaches straddling between the humanities and social and natural sciences which studies human and coastal/marine interactions at the local-scale and through intense fieldwork. Topics of interest include human coastal adaptations past and present; the historical ecology of fisheries and future implications; local forms of marine governance and economic systems; local food security and livelihoods, and indigenous/local ecological knowledge systems among many research themes. In this paper, I explore different strands of CHE in the study of tribal, artisanal, and small-scale industrial fisheries from the mid-90s onward that can contribute to the foundational knowledge necessary for designing and implementing successful coastal fisheries management and conservation programs. Marine conservation has often failed due to a lack of understanding of the fine grained marine human-environmental interactions at the local scale. In this context, I also examine developing and future research directions in CHE, and discuss their potential contribution for filling the gap in existing approaches to actionable scholarship in marine conservation. The strength of many CHE approaches lies in their potential for bridging humanism and natural science, and thus CHE approaches are well equipped to address many of the challenges faced by marine conservation practitioners today.
- Full Text:
- Date Issued: 2019
- Authors: Aswani, Shankar
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125576 , vital:35797 , https://doi.10.1016/j.biocon.2019.05.047
- Description: Coastal human ecology (CHE) is a mixture of different theoretical and thematic approaches straddling between the humanities and social and natural sciences which studies human and coastal/marine interactions at the local-scale and through intense fieldwork. Topics of interest include human coastal adaptations past and present; the historical ecology of fisheries and future implications; local forms of marine governance and economic systems; local food security and livelihoods, and indigenous/local ecological knowledge systems among many research themes. In this paper, I explore different strands of CHE in the study of tribal, artisanal, and small-scale industrial fisheries from the mid-90s onward that can contribute to the foundational knowledge necessary for designing and implementing successful coastal fisheries management and conservation programs. Marine conservation has often failed due to a lack of understanding of the fine grained marine human-environmental interactions at the local scale. In this context, I also examine developing and future research directions in CHE, and discuss their potential contribution for filling the gap in existing approaches to actionable scholarship in marine conservation. The strength of many CHE approaches lies in their potential for bridging humanism and natural science, and thus CHE approaches are well equipped to address many of the challenges faced by marine conservation practitioners today.
- Full Text:
- Date Issued: 2019
An integrated framework for assessing coastal community vulnerability across cultures, oceans and scales
- Aswani, Shankar, Howard, J A, Gasalla, Maria A, Jennings, Sarah, Malherbe, W, Martins, I M, Salim Shyam, Van Putten, Ingrid E, Swathilekshmi, P S, Narayanakumar, R, Watmough G R
- Authors: Aswani, Shankar , Howard, J A , Gasalla, Maria A , Jennings, Sarah , Malherbe, W , Martins, I M , Salim Shyam , Van Putten, Ingrid E , Swathilekshmi, P S , Narayanakumar, R , Watmough G R
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/421581 , vital:71863 , xlink:href="https://doi.org/10.1080/17565529.2018.1442795"
- Description: Coastal communities are some of the most at-risk populations with respect to climate change impacts. It is therefore important to determine the vulnerability of such communities to co-develop viable adaptation options. Global efforts to address this issue include international scientific projects, such as Global Learning for Local Solutions (GULLS), which focuses on five fast warming regions of the southern hemisphere and aims to provide an understanding of the local scale processes influencing community vulnerability that can then be up-scaled to regional, country and global levels. This paper describes the development of a new social and ecological vulnerability framework which integrates exposure, sensitivity and adaptive capacity with the social livelihoods and food security approaches. It also measures community flexibility to understand better the adaptive capacity of different levels of community organization. The translation of the conceptual framework to an implementable method is described and its application in a number of “hotspot” countries, where ocean waters are warming faster than the rest of the world, is presented. Opportunities for cross-cultural comparisons to uncover similarities and differences in vulnerability and adaptation patterns among the study’s coastal communities, which can provide accelerated learning mechanisms to other coastal regions, are highlighted. The social and ecological framework and the associated survey approach allow for future integration of local-level vulnerability data with ecological and oceanographic models.
- Full Text:
- Date Issued: 2019
- Authors: Aswani, Shankar , Howard, J A , Gasalla, Maria A , Jennings, Sarah , Malherbe, W , Martins, I M , Salim Shyam , Van Putten, Ingrid E , Swathilekshmi, P S , Narayanakumar, R , Watmough G R
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/421581 , vital:71863 , xlink:href="https://doi.org/10.1080/17565529.2018.1442795"
- Description: Coastal communities are some of the most at-risk populations with respect to climate change impacts. It is therefore important to determine the vulnerability of such communities to co-develop viable adaptation options. Global efforts to address this issue include international scientific projects, such as Global Learning for Local Solutions (GULLS), which focuses on five fast warming regions of the southern hemisphere and aims to provide an understanding of the local scale processes influencing community vulnerability that can then be up-scaled to regional, country and global levels. This paper describes the development of a new social and ecological vulnerability framework which integrates exposure, sensitivity and adaptive capacity with the social livelihoods and food security approaches. It also measures community flexibility to understand better the adaptive capacity of different levels of community organization. The translation of the conceptual framework to an implementable method is described and its application in a number of “hotspot” countries, where ocean waters are warming faster than the rest of the world, is presented. Opportunities for cross-cultural comparisons to uncover similarities and differences in vulnerability and adaptation patterns among the study’s coastal communities, which can provide accelerated learning mechanisms to other coastal regions, are highlighted. The social and ecological framework and the associated survey approach allow for future integration of local-level vulnerability data with ecological and oceanographic models.
- Full Text:
- Date Issued: 2019
Biosynthesis of silver nanoparticles from Acacia mearnsii De Wild stem bark and its antinociceptive properties
- Avoseh, Opeyemi N, Oyedeji, Opeoluwa O, Aremu, Olukayode, Nkeh-Chungag, Benedicta N, Songca, Sandile P, Oyedeji, Adebola Omowunmi, Mohan, Sneha, Oluwafemi, Oluwatobi S
- Authors: Avoseh, Opeyemi N , Oyedeji, Opeoluwa O , Aremu, Olukayode , Nkeh-Chungag, Benedicta N , Songca, Sandile P , Oyedeji, Adebola Omowunmi , Mohan, Sneha , Oluwafemi, Oluwatobi S
- Date: 2017
- Subjects: Metal nanoparticles , Acacia mearnsii , Nociceptive pain
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/1528 , vital:37774 , https://doi.org/10.1080/17518253.2017.1287310
- Description: The biosynthesis of silver nanoparticles (Ag-NPs) using the hydrosol extract of the dry stem bark of Acacia mearnsii as reducing and capping agents, and their antinociceptive properties are hereby reported. By varying the temperature and reaction time, the temporal evolution of the optical and morphological properties of the as-synthesized material was investigated. The NPs were characterized by UV–visible absorption spectroscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive x-ray spectroscopy (EDS) and x-ray diffractometry (XRD) The optical analyses show that the position of the maximum surface plasmon resonance (SPR) peak is red-shifted as the reaction temperature decreased. The TEM micrographs show that the as-synthesized Ag-NPs are spherical while the X-ray diffraction shows that the material is highly crystalline with face-centered cubic structures. The anti-inflammatory efficacy, analyzed by the formalin model, indicates that the as-synthesized Ag-NPs are very effective, with an inhibition rate of about 76%.
- Full Text:
- Date Issued: 2017
- Authors: Avoseh, Opeyemi N , Oyedeji, Opeoluwa O , Aremu, Olukayode , Nkeh-Chungag, Benedicta N , Songca, Sandile P , Oyedeji, Adebola Omowunmi , Mohan, Sneha , Oluwafemi, Oluwatobi S
- Date: 2017
- Subjects: Metal nanoparticles , Acacia mearnsii , Nociceptive pain
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/11260/1528 , vital:37774 , https://doi.org/10.1080/17518253.2017.1287310
- Description: The biosynthesis of silver nanoparticles (Ag-NPs) using the hydrosol extract of the dry stem bark of Acacia mearnsii as reducing and capping agents, and their antinociceptive properties are hereby reported. By varying the temperature and reaction time, the temporal evolution of the optical and morphological properties of the as-synthesized material was investigated. The NPs were characterized by UV–visible absorption spectroscopy, transmission electron microscopy (TEM), Fourier transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), energy-dispersive x-ray spectroscopy (EDS) and x-ray diffractometry (XRD) The optical analyses show that the position of the maximum surface plasmon resonance (SPR) peak is red-shifted as the reaction temperature decreased. The TEM micrographs show that the as-synthesized Ag-NPs are spherical while the X-ray diffraction shows that the material is highly crystalline with face-centered cubic structures. The anti-inflammatory efficacy, analyzed by the formalin model, indicates that the as-synthesized Ag-NPs are very effective, with an inhibition rate of about 76%.
- Full Text:
- Date Issued: 2017
Investigating the nature of grade six after school mathematics club learners’ shifts in mathematical number sense and procedural fluency
- Authors: Baart, Noluntu Via
- Date: 2019
- Subjects: Mathematics -- Study and teaching (Elementary) -- South Africa , Mathematics -- Study and teaching (Elementary) -- South Africa -- Case studies , Numeracy -- South Africa
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/96825 , vital:31326
- Description: A wide range of research locally points to intermediate phase learners having extremely weak basic number sense resulting in the dominance of inefficient strategies for calculations with the four operations, irrespective of the number range. The grade six Annual National Assessments (ANA) diagnostic reports for 2012 to 2014 also point to errors and misconceptions that tend to dominate learners’ computations in the four basic operations; such errors are often attributed to the use of either tallies or incorrectly applied mathematical procedures. Having the above context in mind and following informal conversations with teachers in the Uitenhage Education District, five teachers expressed an interest in running the afterschool mathematics clubs based on the South African Numeracy Chair (SANC) project model. The SANC project team ran workshops in April, May and June 2016 with nine teachers (five as facilitators and four others as co-facilitators in five different club sites) in which teachers were provided with key resources for use in their clubs. Fifteen club sessions ran in each club with grade six learners across the 2nd and 3rd terms. These clubs form the empirical field for this research, which aims to investigate the nature of learners’ evolving number sense, procedural fluency and teachers’ experiences of working with learners in the club space. The unit of analysis in this study is both the shifts evident in learners’ number sense and procedural fluency as a result of participating in the clubs and the teacher’s experiences of working with learners in those clubs as club facilitators. A social constructivist perspective of learning guides this study. Especially Vygotsky’s (1978) notion that cognitive development stems from social interactions and guided learning within the Zone of Proximal Development (ZPD) of children, guided by more knowledgeable others. Furthermore, Kilpatrick et al.’s (2001) strands of mathematical proficiency provide the conceptual frame with a particular focus on procedural fluency and number sense. A mixed method approach to data collection was used. Quantitative data has been drawn from learner’s scores on pre- and post- assessments on four basic operations. Visual progression spectra have been adopted from the Pushing for Progression (PfP) Programme which is an intervention Programme developed by the SANC project for club facilitators. They provide explanations of learner progression trajectories and how to analyse learner methods. Qualitative narratives were drawn from learner progression data, as well as teacher post club questionnaires and one-to-one teacher interviews. The findings of this research suggest that learner workings when used in conjunction with visual progression spectra can provide important clues to researchers and teachers. This in turn contributes to an understanding of where learners are in their mathematical learning and gives ideas for how to support learners to progress using more flexible methods of calculation, particularly for poor performing learners. Included, is the discussion of the effectiveness of the club space to enable such shifts and improve learner flexibility, fluency and performance as displayed in learner methods and scores of the pre- and post- assessments. The teachers’ observations about the relaxed atmosphere in the club space, small sized groups, learning through play with co-members may have enabled the shifts in procedural fluency and number sense in club learners. Additionally, implications of the study are discussed, and tentative recommendations are made for the DBE to consider.
- Full Text:
- Date Issued: 2019
- Authors: Baart, Noluntu Via
- Date: 2019
- Subjects: Mathematics -- Study and teaching (Elementary) -- South Africa , Mathematics -- Study and teaching (Elementary) -- South Africa -- Case studies , Numeracy -- South Africa
- Language: English
- Type: text , Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/96825 , vital:31326
- Description: A wide range of research locally points to intermediate phase learners having extremely weak basic number sense resulting in the dominance of inefficient strategies for calculations with the four operations, irrespective of the number range. The grade six Annual National Assessments (ANA) diagnostic reports for 2012 to 2014 also point to errors and misconceptions that tend to dominate learners’ computations in the four basic operations; such errors are often attributed to the use of either tallies or incorrectly applied mathematical procedures. Having the above context in mind and following informal conversations with teachers in the Uitenhage Education District, five teachers expressed an interest in running the afterschool mathematics clubs based on the South African Numeracy Chair (SANC) project model. The SANC project team ran workshops in April, May and June 2016 with nine teachers (five as facilitators and four others as co-facilitators in five different club sites) in which teachers were provided with key resources for use in their clubs. Fifteen club sessions ran in each club with grade six learners across the 2nd and 3rd terms. These clubs form the empirical field for this research, which aims to investigate the nature of learners’ evolving number sense, procedural fluency and teachers’ experiences of working with learners in the club space. The unit of analysis in this study is both the shifts evident in learners’ number sense and procedural fluency as a result of participating in the clubs and the teacher’s experiences of working with learners in those clubs as club facilitators. A social constructivist perspective of learning guides this study. Especially Vygotsky’s (1978) notion that cognitive development stems from social interactions and guided learning within the Zone of Proximal Development (ZPD) of children, guided by more knowledgeable others. Furthermore, Kilpatrick et al.’s (2001) strands of mathematical proficiency provide the conceptual frame with a particular focus on procedural fluency and number sense. A mixed method approach to data collection was used. Quantitative data has been drawn from learner’s scores on pre- and post- assessments on four basic operations. Visual progression spectra have been adopted from the Pushing for Progression (PfP) Programme which is an intervention Programme developed by the SANC project for club facilitators. They provide explanations of learner progression trajectories and how to analyse learner methods. Qualitative narratives were drawn from learner progression data, as well as teacher post club questionnaires and one-to-one teacher interviews. The findings of this research suggest that learner workings when used in conjunction with visual progression spectra can provide important clues to researchers and teachers. This in turn contributes to an understanding of where learners are in their mathematical learning and gives ideas for how to support learners to progress using more flexible methods of calculation, particularly for poor performing learners. Included, is the discussion of the effectiveness of the club space to enable such shifts and improve learner flexibility, fluency and performance as displayed in learner methods and scores of the pre- and post- assessments. The teachers’ observations about the relaxed atmosphere in the club space, small sized groups, learning through play with co-members may have enabled the shifts in procedural fluency and number sense in club learners. Additionally, implications of the study are discussed, and tentative recommendations are made for the DBE to consider.
- Full Text:
- Date Issued: 2019
Preparation of NIR absorbing axial substituted tin (iv) porphyrins and their photocytotoxic properties
- Babu, Balaji, Amuhaya, Edith K, Oluwole, David O, Prinsloo, Earl, Mack, John, Nyokong, Tebello
- Authors: Babu, Balaji , Amuhaya, Edith K , Oluwole, David O , Prinsloo, Earl , Mack, John , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/234592 , vital:50211 , xlink:href="https://doi.org/10.1039/C8MD00373D"
- Description: Sn(IV) porphyrins ([Sn(IV)TTP(3PyO)2] (5) and [Sn(IV)TPP(3PyO)2] (6) [tetrathienylporphyrin (TTP), tetraphenylporphyrin (TPP), and pyridyloxy (PyO)]) were prepared and characterized and their photocytotoxicity upon irradiation with 625 nm light has been studied. The presence of the 3PyO axial ligands was found to limit the aggregation and enhance the solubility of 5 and 6 in DMF/H2O (1 : 1). The photophysical properties and photodynamic therapy (PDT) activity of the meso-2-thienyl and meso-phenyl-substituted Sn(IV) porphyrins are compared. 5 and 6 were found to be photocytotoxic in MCF-7 cancer cells when irradiated with a Thorlabs M625L3 LED at 625 nm but remained nontoxic in the dark. The PDT activity of Sn(IV) meso-tetra-2-thienylporphyrin 5 was found to be significantly enhanced relative to its analogous tetraphenylporphyrin 6. There is a marked red-shift of the Q00 band of 5 into the therapeutic window due to the meso-2-thienyl rings, and 5 has an unusually high singlet oxygen quantum yield value of 0.83 in DMF. The results demonstrate that readily synthesized axially ligated Sn(IV) meso-arylporphyrins are potentially suitable for use as singlet oxygen photosensitizers in biomedical applications and merit further in depth investigation in this context.
- Full Text:
- Date Issued: 2019
- Authors: Babu, Balaji , Amuhaya, Edith K , Oluwole, David O , Prinsloo, Earl , Mack, John , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/234592 , vital:50211 , xlink:href="https://doi.org/10.1039/C8MD00373D"
- Description: Sn(IV) porphyrins ([Sn(IV)TTP(3PyO)2] (5) and [Sn(IV)TPP(3PyO)2] (6) [tetrathienylporphyrin (TTP), tetraphenylporphyrin (TPP), and pyridyloxy (PyO)]) were prepared and characterized and their photocytotoxicity upon irradiation with 625 nm light has been studied. The presence of the 3PyO axial ligands was found to limit the aggregation and enhance the solubility of 5 and 6 in DMF/H2O (1 : 1). The photophysical properties and photodynamic therapy (PDT) activity of the meso-2-thienyl and meso-phenyl-substituted Sn(IV) porphyrins are compared. 5 and 6 were found to be photocytotoxic in MCF-7 cancer cells when irradiated with a Thorlabs M625L3 LED at 625 nm but remained nontoxic in the dark. The PDT activity of Sn(IV) meso-tetra-2-thienylporphyrin 5 was found to be significantly enhanced relative to its analogous tetraphenylporphyrin 6. There is a marked red-shift of the Q00 band of 5 into the therapeutic window due to the meso-2-thienyl rings, and 5 has an unusually high singlet oxygen quantum yield value of 0.83 in DMF. The results demonstrate that readily synthesized axially ligated Sn(IV) meso-arylporphyrins are potentially suitable for use as singlet oxygen photosensitizers in biomedical applications and merit further in depth investigation in this context.
- Full Text:
- Date Issued: 2019
Synthesis, characterization and photodynamic activity of Sn (iv) triarylcorroles with red-shifted Q bands
- Babu, Balaji, Prinsloo, Earl, Mack, John, Nyokong, Tebello
- Authors: Babu, Balaji , Prinsloo, Earl , Mack, John , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187521 , vital:44668 , xlink:href="https://doi.org/10.1039/C9NJ03391B"
- Description: Two Sn(IV) triarylcorroles were synthesised and characterized. The absorption spectrum of a meso-thien-2-yl substituted tin(IV)corrole (1-Sn) is red shifted compared to its phenyl analogue (2-Sn) and shows no sign of aggregation in solution. 1-Sn and 2-Sn exhibited singlet oxygen quantum yields of 0.87 and 0.54 in DMF, and have a triplet lifetime of 31 and 50 μs, respectively. Time dependent cellular uptake in MCF-7 cells for 1-Sn reached a peak at 24 h, and 1-Sn was found to be more lipophilic than 2-Sn. 1-Sn showed good photo-cytotoxicity on exposure to a Thorlabs 625 nm LED with an IC50 value of 3.2 μM and remained inactive in the dark.
- Full Text:
- Date Issued: 2019
- Authors: Babu, Balaji , Prinsloo, Earl , Mack, John , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/187521 , vital:44668 , xlink:href="https://doi.org/10.1039/C9NJ03391B"
- Description: Two Sn(IV) triarylcorroles were synthesised and characterized. The absorption spectrum of a meso-thien-2-yl substituted tin(IV)corrole (1-Sn) is red shifted compared to its phenyl analogue (2-Sn) and shows no sign of aggregation in solution. 1-Sn and 2-Sn exhibited singlet oxygen quantum yields of 0.87 and 0.54 in DMF, and have a triplet lifetime of 31 and 50 μs, respectively. Time dependent cellular uptake in MCF-7 cells for 1-Sn reached a peak at 24 h, and 1-Sn was found to be more lipophilic than 2-Sn. 1-Sn showed good photo-cytotoxicity on exposure to a Thorlabs 625 nm LED with an IC50 value of 3.2 μM and remained inactive in the dark.
- Full Text:
- Date Issued: 2019
The influence of artificial light on the foraging efficiency and diet of insect eating bats
- Authors: Bailey, Lauren
- Date: 2019
- Subjects: Predation (Biology) , Bats -- Effect of light on , Bats -- Nutrition , Moths
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/76376 , vital:30555
- Description: Artificial light may be altering the interactions between bats and moth prey. Unable to make use of bat evasion strategies around artificial light, eared moths are susceptible to exploitation by syntonic bats (using echolocation frequencies between 20-50 kHz within the hearing range of eared moths). Using a handheld plasma metabolite analyzer, I evaluated the foraging success of syntonic bats and rarer allotonic bats (using echolocation frequencies outside the hearing range of eared moths), in areas with artificial light and in areas of natural darkness. I used microscope diet analysis to determine whether bats were consuming more or fewer moths in areas with artificial light and in areas of natural darkness. Syntonic bats were more selective for moth prey under lit conditions, likely owing to a reduction in the ability of tympanate moths to evade bats. Moths increased in the diets of generalist syntonic bats (Pipistrellus hesperidus) foraging around artificial light sources. Some P. hesperidus individuals showed high β-hydroxybutyrate levels around lights, but there was no difference in β-hydroxybutyrate levels between lit and unlit conditions. There is insufficient evidence to reject the null hypothesis that the foraging success of syntonic bats is equivalent in lit vs unlit conditions. The foraging success and diets of allotonic bats, Rhinolophus capensis, appear to be negligibly impacted by artificial light on a small scale. My study emphasizes the need for a mechanistic understanding of the influence of artificial light on the foraging success of bat species. Bat-moth interactions may be influenced by other factors apart from the common assumption that increased refuelling rates will occur in syntonic species foraging on moths around artificial light.
- Full Text:
- Date Issued: 2019
- Authors: Bailey, Lauren
- Date: 2019
- Subjects: Predation (Biology) , Bats -- Effect of light on , Bats -- Nutrition , Moths
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/76376 , vital:30555
- Description: Artificial light may be altering the interactions between bats and moth prey. Unable to make use of bat evasion strategies around artificial light, eared moths are susceptible to exploitation by syntonic bats (using echolocation frequencies between 20-50 kHz within the hearing range of eared moths). Using a handheld plasma metabolite analyzer, I evaluated the foraging success of syntonic bats and rarer allotonic bats (using echolocation frequencies outside the hearing range of eared moths), in areas with artificial light and in areas of natural darkness. I used microscope diet analysis to determine whether bats were consuming more or fewer moths in areas with artificial light and in areas of natural darkness. Syntonic bats were more selective for moth prey under lit conditions, likely owing to a reduction in the ability of tympanate moths to evade bats. Moths increased in the diets of generalist syntonic bats (Pipistrellus hesperidus) foraging around artificial light sources. Some P. hesperidus individuals showed high β-hydroxybutyrate levels around lights, but there was no difference in β-hydroxybutyrate levels between lit and unlit conditions. There is insufficient evidence to reject the null hypothesis that the foraging success of syntonic bats is equivalent in lit vs unlit conditions. The foraging success and diets of allotonic bats, Rhinolophus capensis, appear to be negligibly impacted by artificial light on a small scale. My study emphasizes the need for a mechanistic understanding of the influence of artificial light on the foraging success of bat species. Bat-moth interactions may be influenced by other factors apart from the common assumption that increased refuelling rates will occur in syntonic species foraging on moths around artificial light.
- Full Text:
- Date Issued: 2019
An experimental test of the allotonic frequency hypothesis to isolate the effects of light pollution on bat prey selection:
- Bailey, Lauren A, Brigham, R Mark, Bohn, Shelby J, Boyles, Justin G, Smit, Ben
- Authors: Bailey, Lauren A , Brigham, R Mark , Bohn, Shelby J , Boyles, Justin G , Smit, Ben
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158309 , vital:40171 , https://0-doi.org.wam.seals.ac.za/10.1007/s00442-019-04417-w
- Description: Artificial lights may be altering interactions between bats and moth prey. According to the allotonic frequency hypothesis (AFH), eared moths are generally unavailable as prey for syntonic bats (i.e., bats that use echolocation frequencies between 20 and 50 kHz within the hearing range of eared moths) due to the moths’ ability to detect syntonic bat echolocation. Syntonic bats therefore feed mainly on beetles, flies, true bugs, and non-eared moths. The AFH is expected to be violated around lights where eared moths are susceptible to exploitation by syntonic bats because moths’ evasive strategies become less effective. The hypothesis has been tested to date almost exclusively in areas with permanent lighting, where the effects of lights on bat diets are confounded with other aspects of human habitat alteration. We undertook diet analysis in areas with short-term, localized artificial lighting to isolate the effects of artificial lighting and determine if syntonic and allotonic bats (i.e., bats that use echolocation frequencies outside the hearing range of eared moths) consumed more moths under conditions of artificial lights than in natural darkness.
- Full Text:
- Date Issued: 2019
- Authors: Bailey, Lauren A , Brigham, R Mark , Bohn, Shelby J , Boyles, Justin G , Smit, Ben
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158309 , vital:40171 , https://0-doi.org.wam.seals.ac.za/10.1007/s00442-019-04417-w
- Description: Artificial lights may be altering interactions between bats and moth prey. According to the allotonic frequency hypothesis (AFH), eared moths are generally unavailable as prey for syntonic bats (i.e., bats that use echolocation frequencies between 20 and 50 kHz within the hearing range of eared moths) due to the moths’ ability to detect syntonic bat echolocation. Syntonic bats therefore feed mainly on beetles, flies, true bugs, and non-eared moths. The AFH is expected to be violated around lights where eared moths are susceptible to exploitation by syntonic bats because moths’ evasive strategies become less effective. The hypothesis has been tested to date almost exclusively in areas with permanent lighting, where the effects of lights on bat diets are confounded with other aspects of human habitat alteration. We undertook diet analysis in areas with short-term, localized artificial lighting to isolate the effects of artificial lighting and determine if syntonic and allotonic bats (i.e., bats that use echolocation frequencies outside the hearing range of eared moths) consumed more moths under conditions of artificial lights than in natural darkness.
- Full Text:
- Date Issued: 2019
[Post] Colonial Histories: Trauma, Memory and Reconciliation in the Context of the Angolan Civil War
- Authors: Baines, Gary F
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125752 , vital:35814 , https://doi.10.1080/03612759.2019.1587342
- Description: In 2007, a former South African Defence Force (SADF) paratrooper, Marius van Niekerk, embarked on a journey to confront his shameful memories relating to his role in the Angolan Civil War. From Sweden (where he had gone into exile), Van Niekerk returned to Angola, where he had been deployed during the mid-1980s, and recruited three other veterans of the war to join his party: Patrick Johannes, who had been coerced to fight for the Popular Armed Forces for the Liberation of Angola (FAPLA); Samuel Machado Amaru, who was forcefully enlisted by the National Union for the Total Independence of Angola (UNITA); and Mario Mahonga, who had fought for the Portuguese colonial army before he was recruited by the SADF to fight against the Popular Movement for the Liberation of Angola (MPLA) regime. Van Niekerk had been conscripted at the age of seventeen, and the others had been coerced into their respective militias at more tender ages. It is not clear how the three Angolans were induced to participate in the project, whose objectives they evidently did not share.
- Full Text:
- Date Issued: 2019
[Post] Colonial Histories: Trauma, Memory and Reconciliation in the Context of the Angolan Civil War
- Authors: Baines, Gary F
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/125752 , vital:35814 , https://doi.10.1080/03612759.2019.1587342
- Description: In 2007, a former South African Defence Force (SADF) paratrooper, Marius van Niekerk, embarked on a journey to confront his shameful memories relating to his role in the Angolan Civil War. From Sweden (where he had gone into exile), Van Niekerk returned to Angola, where he had been deployed during the mid-1980s, and recruited three other veterans of the war to join his party: Patrick Johannes, who had been coerced to fight for the Popular Armed Forces for the Liberation of Angola (FAPLA); Samuel Machado Amaru, who was forcefully enlisted by the National Union for the Total Independence of Angola (UNITA); and Mario Mahonga, who had fought for the Portuguese colonial army before he was recruited by the SADF to fight against the Popular Movement for the Liberation of Angola (MPLA) regime. Van Niekerk had been conscripted at the age of seventeen, and the others had been coerced into their respective militias at more tender ages. It is not clear how the three Angolans were induced to participate in the project, whose objectives they evidently did not share.
- Full Text:
- Date Issued: 2019
Understanding the learning that occurs through up-skilling opportunities and practices in the marine sector of South Africa
- Authors: Bell, Caroline Margaret
- Date: 2019
- Subjects: Biodiversity conservation -- South Africa , Human capital -- South Africa , Marine sciences -- Employees -- South Africa -- Training of , Biodiversity Human Capital Development Strategy (South Africa)
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/93966 , vital:30977
- Description: South Africa is characterised by cultural and biological diversity which constitute a unique context in which to conduct educational research, such as this doctoral study looking at human capital development in the marine biodiversity context. The drive for transformation in the country is also a major factor to consider when researching any sector of the economy, in this case, the biodiversity sector. The biodiversity sector includes organisations involved in biodiversity conservation, research and management. Previous research in the sector has found a clear need for well-thought out workplace skills plans within conservation and research organisations. The national Biodiversity Human Capital Development Strategy that was produced in 2010 by the South African National Biodiversity Institute outlines how all the organisations involved in the biodiversity sector of South Africa need to participate in strengthening the sector through a range of human capital development strategies. This includes extending the existing human capacity of managers and scientists who are already in the workplace, i.e. up-skilling. In particular, ‘scarce’ skills, as identified by the national Environmental Sector Skills Plan need further attention and development. The scarce skills relevant to this study are: protected area managers; ecosystem managers and post-graduate researchers, hence the focus on managers and scientists in this research. The marine sector falls within the biodiversity sector and it faces multiple conservation challenges which are complex and it is therefore essential to have skilled and capable managers and scientists in place. By investigating the up-skilling opportunities and practices available to these marine professionals, the goal is to understand if and how learning takes place in the marine sector of South Africa. The main research question of this study is: How do up-skilling opportunities and practices enable learning in, through and for the workplace, by marine professionals? In addition, three sub-questions provide finer details and introduce the central concepts of the research: I. What up-skilling opportunities and professional practices exist in or for, marine research and conservation organisations and how are they constituted and enacted via practice-based sayings, doings and relatings? II. How do the individuals learn and exercise their agency within the socio-material realities of the marine scientific and management context, through making use of up-skilling opportunities that are both formal (e.g. course based) and informal? III. How do generative mechanisms shape the constitution and enactment of up-skilling opportunities and practices, and the learning and agency of marine professionals (scientists and managers)? The theoretical work of this study consisted of, first, considering sensitising concepts which included: defining skill and knowledge; considering what an up-skilling opportunity might look like; workplace learning (both formal and informal learning); professional practices, lifelong learning or adult education, and agency in the workplace. Critical realism was then employed as the meta-theory that underlabours this research, while the substantive theories used for analysis purposes were socio-materialism and practice theory. Of course, critical realism is a socio-material theory itself, and Bhaskar’s four-planar social being or Social Cube was used to interpret and synthesise the findings in the data chapters. The methodological framework of this study explores the implications of critical realism for research design and analysis and includes a contextual profiling phase, semi-structured interviews, analysis of documents and peer-reviewed papers, as well as observations. There are nine case studies that form the focus of this research and in total 18 research participants were involved. Data analysis included abduction and retroduction as the primary modes of inference and the main analytical tool was the framework of practice architectures where I took the ‘sayings’, ‘doings’ and ‘relatings’ as themes. Further themes were developed from the other relevant theories used in this study; hence socio-materialism, learning, agency, and formal and informal opportunities, were also used as themes when coding the data. Issues around validity, ethics and reflexivity are key elements of the research design and were carefully considered throughout the research process. The principal data chapters are structured in such a way that each sub-question is considered and ultimately the findings are presented in the form of generative mechanisms which included: the politics of social transformation and knowledge as a driving force of up-skilling; the influence of individual disposition and passion or will; the importance of the socio-material realities and realistic expectations; and how relationality is critical for the marine sector. Agency was a cross-cutting theme in all the discussions around learning, practices and the role of the material, and was highly influential on the mechanisms that have been described in this study. The experiences, events and mechanisms that were uncovered in this research provide insight into the forms of learning as these relate to up-skilling that occur in the marine sector, as well as the complex relationships between formal and informal learning. The professional practices that occur in the everyday working lives of the marine professionals were shown to be an integral part of the learning process, while formal, certified opportunities are important for strengthening the field and building conservation competence in the country. By uncovering the deeper structures and mechanisms that have power and causal efficacy when it comes to up-skilling opportunities, learning and professional practices, this study has contributed to the field of environmental education as it shows how up-skilling processes operate in complex formations that involve formal and informal learning processes in workplaces. The study also offers a more nuanced view of the relational objects in this field, such as up-skilling and workplace learning, via the inclusion of a socio-material analysis. Through a theoretical and methodological framework that focused on the material using the tools of practice theory and Bhaskar’s depth ontology and four-planar social being (to synthesise and interpret the findings from a critical realist perspective), this research highlights the unique context of up-skilling opportunities and practices in the marine sector and reveals the crucial role of agency in workplace practices. This leads to a better understanding of the up-skilling opportunities and practices of marine professionals in South Africa, which ultimately contributes towards improved human capital development in the biodiversity and environmental sectors. Through offering more complex insights into the forms of learning and up-skilling, as well as a distinct methodological contribution, this research has broader relevance for workplace learning research.
- Full Text:
- Date Issued: 2019
- Authors: Bell, Caroline Margaret
- Date: 2019
- Subjects: Biodiversity conservation -- South Africa , Human capital -- South Africa , Marine sciences -- Employees -- South Africa -- Training of , Biodiversity Human Capital Development Strategy (South Africa)
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/93966 , vital:30977
- Description: South Africa is characterised by cultural and biological diversity which constitute a unique context in which to conduct educational research, such as this doctoral study looking at human capital development in the marine biodiversity context. The drive for transformation in the country is also a major factor to consider when researching any sector of the economy, in this case, the biodiversity sector. The biodiversity sector includes organisations involved in biodiversity conservation, research and management. Previous research in the sector has found a clear need for well-thought out workplace skills plans within conservation and research organisations. The national Biodiversity Human Capital Development Strategy that was produced in 2010 by the South African National Biodiversity Institute outlines how all the organisations involved in the biodiversity sector of South Africa need to participate in strengthening the sector through a range of human capital development strategies. This includes extending the existing human capacity of managers and scientists who are already in the workplace, i.e. up-skilling. In particular, ‘scarce’ skills, as identified by the national Environmental Sector Skills Plan need further attention and development. The scarce skills relevant to this study are: protected area managers; ecosystem managers and post-graduate researchers, hence the focus on managers and scientists in this research. The marine sector falls within the biodiversity sector and it faces multiple conservation challenges which are complex and it is therefore essential to have skilled and capable managers and scientists in place. By investigating the up-skilling opportunities and practices available to these marine professionals, the goal is to understand if and how learning takes place in the marine sector of South Africa. The main research question of this study is: How do up-skilling opportunities and practices enable learning in, through and for the workplace, by marine professionals? In addition, three sub-questions provide finer details and introduce the central concepts of the research: I. What up-skilling opportunities and professional practices exist in or for, marine research and conservation organisations and how are they constituted and enacted via practice-based sayings, doings and relatings? II. How do the individuals learn and exercise their agency within the socio-material realities of the marine scientific and management context, through making use of up-skilling opportunities that are both formal (e.g. course based) and informal? III. How do generative mechanisms shape the constitution and enactment of up-skilling opportunities and practices, and the learning and agency of marine professionals (scientists and managers)? The theoretical work of this study consisted of, first, considering sensitising concepts which included: defining skill and knowledge; considering what an up-skilling opportunity might look like; workplace learning (both formal and informal learning); professional practices, lifelong learning or adult education, and agency in the workplace. Critical realism was then employed as the meta-theory that underlabours this research, while the substantive theories used for analysis purposes were socio-materialism and practice theory. Of course, critical realism is a socio-material theory itself, and Bhaskar’s four-planar social being or Social Cube was used to interpret and synthesise the findings in the data chapters. The methodological framework of this study explores the implications of critical realism for research design and analysis and includes a contextual profiling phase, semi-structured interviews, analysis of documents and peer-reviewed papers, as well as observations. There are nine case studies that form the focus of this research and in total 18 research participants were involved. Data analysis included abduction and retroduction as the primary modes of inference and the main analytical tool was the framework of practice architectures where I took the ‘sayings’, ‘doings’ and ‘relatings’ as themes. Further themes were developed from the other relevant theories used in this study; hence socio-materialism, learning, agency, and formal and informal opportunities, were also used as themes when coding the data. Issues around validity, ethics and reflexivity are key elements of the research design and were carefully considered throughout the research process. The principal data chapters are structured in such a way that each sub-question is considered and ultimately the findings are presented in the form of generative mechanisms which included: the politics of social transformation and knowledge as a driving force of up-skilling; the influence of individual disposition and passion or will; the importance of the socio-material realities and realistic expectations; and how relationality is critical for the marine sector. Agency was a cross-cutting theme in all the discussions around learning, practices and the role of the material, and was highly influential on the mechanisms that have been described in this study. The experiences, events and mechanisms that were uncovered in this research provide insight into the forms of learning as these relate to up-skilling that occur in the marine sector, as well as the complex relationships between formal and informal learning. The professional practices that occur in the everyday working lives of the marine professionals were shown to be an integral part of the learning process, while formal, certified opportunities are important for strengthening the field and building conservation competence in the country. By uncovering the deeper structures and mechanisms that have power and causal efficacy when it comes to up-skilling opportunities, learning and professional practices, this study has contributed to the field of environmental education as it shows how up-skilling processes operate in complex formations that involve formal and informal learning processes in workplaces. The study also offers a more nuanced view of the relational objects in this field, such as up-skilling and workplace learning, via the inclusion of a socio-material analysis. Through a theoretical and methodological framework that focused on the material using the tools of practice theory and Bhaskar’s depth ontology and four-planar social being (to synthesise and interpret the findings from a critical realist perspective), this research highlights the unique context of up-skilling opportunities and practices in the marine sector and reveals the crucial role of agency in workplace practices. This leads to a better understanding of the up-skilling opportunities and practices of marine professionals in South Africa, which ultimately contributes towards improved human capital development in the biodiversity and environmental sectors. Through offering more complex insights into the forms of learning and up-skilling, as well as a distinct methodological contribution, this research has broader relevance for workplace learning research.
- Full Text:
- Date Issued: 2019
An exploration of social media as a key site for the expression of post-racial politics
- Authors: Bell, Joshua
- Date: 2019
- Subjects: Social media -- Political aspects -- South Africa , South Africa -- Politics and government -- 1994- , South Africa -- In mass media
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/94049 , vital:30995
- Description: This research sets out to examine colourblind racism in contemporary South Africa, specifically, as expressed on social media networks. In South Africa, a nation lauded for its transition from Apartheid to liberal democracy, racism still continues to exist. In the new democracy, racism continues in old, familiar forms but it has been suggested that racism also assumes new and emergent forms such as ‘colourblind’ racism. This is evident in recent controversies involving local public figures and their expressions of ‘soft’, ‘colourblind’ racism on Facebook. It is the new platforms and modes of racism unique to democratic South Africa which this thesis attempts to explore. Specifically, this study is framed by ‘post-racialism’, a concept developed by scholars globally to capture the suggestion that in liberal democratic societies across the world, racism continues with racial inequality now underpinned by an ideology of colourblindness as opposed to overt policies of segregation. Colourblindness denies the relevance of race as a collective issue, proposing instead that other social factors such as class are more pertinent in considerations of social inequality. The purpose of colourblind narratives may be identified as the reduction of racism to mere individual action, denying systemic white privilege and historical responsibility for reparation as well as preventing racially subjugated groups from critically interrogating racial power and privilege (Goldberg, 2015: 28-30). Post-racial theorists agree that the projection of colourblind politics which claims to no longer ‘see race’ has instead served to secure the normalisation of white privilege and black subjugation (Bonilla-Silva et al, 2004: 559-560). The purported existence of colourblind /post-racial racism and its impact requires exploration in the context of South Africa today. In expanding on the definition of racism, we are able to see that racism is an adaptive system of power that is able to reproduce and reconceptualise itself to changes within society. As modalities of racism have evolved, so have the platforms for its propagation. This research offers social media as a site of exploration for post-racial narratives. The case studies of Penny Sparrow, Helen Zille and Mabel Jansen are presented in this study as exemplars of post-racial liberalism, denial and exclusion. This research calls for the expansion of racial understanding so as to contest racial power structures as a continuing systemic issue in contemporary South Africa.
- Full Text:
- Date Issued: 2019
- Authors: Bell, Joshua
- Date: 2019
- Subjects: Social media -- Political aspects -- South Africa , South Africa -- Politics and government -- 1994- , South Africa -- In mass media
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/94049 , vital:30995
- Description: This research sets out to examine colourblind racism in contemporary South Africa, specifically, as expressed on social media networks. In South Africa, a nation lauded for its transition from Apartheid to liberal democracy, racism still continues to exist. In the new democracy, racism continues in old, familiar forms but it has been suggested that racism also assumes new and emergent forms such as ‘colourblind’ racism. This is evident in recent controversies involving local public figures and their expressions of ‘soft’, ‘colourblind’ racism on Facebook. It is the new platforms and modes of racism unique to democratic South Africa which this thesis attempts to explore. Specifically, this study is framed by ‘post-racialism’, a concept developed by scholars globally to capture the suggestion that in liberal democratic societies across the world, racism continues with racial inequality now underpinned by an ideology of colourblindness as opposed to overt policies of segregation. Colourblindness denies the relevance of race as a collective issue, proposing instead that other social factors such as class are more pertinent in considerations of social inequality. The purpose of colourblind narratives may be identified as the reduction of racism to mere individual action, denying systemic white privilege and historical responsibility for reparation as well as preventing racially subjugated groups from critically interrogating racial power and privilege (Goldberg, 2015: 28-30). Post-racial theorists agree that the projection of colourblind politics which claims to no longer ‘see race’ has instead served to secure the normalisation of white privilege and black subjugation (Bonilla-Silva et al, 2004: 559-560). The purported existence of colourblind /post-racial racism and its impact requires exploration in the context of South Africa today. In expanding on the definition of racism, we are able to see that racism is an adaptive system of power that is able to reproduce and reconceptualise itself to changes within society. As modalities of racism have evolved, so have the platforms for its propagation. This research offers social media as a site of exploration for post-racial narratives. The case studies of Penny Sparrow, Helen Zille and Mabel Jansen are presented in this study as exemplars of post-racial liberalism, denial and exclusion. This research calls for the expansion of racial understanding so as to contest racial power structures as a continuing systemic issue in contemporary South Africa.
- Full Text:
- Date Issued: 2019
Rapid recovery of macroinvertebrates in a South African stream treated with rotenone:
- Bellingan, Terence A, Hugo, Sanet, Woodford, Darragh J, Gouws, Jeanne, Villet, Martin H, Weyl, Olaf L F
- Authors: Bellingan, Terence A , Hugo, Sanet , Woodford, Darragh J , Gouws, Jeanne , Villet, Martin H , Weyl, Olaf L F
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140751 , vital:37915 , DOI: 10.1007/s10750-019-3885-z
- Description: South Africa’s Cape Fold Ecoregion supports a unique freshwater fish assemblage with many endemics. To mitigate impacts of alien invasive fishes on this unique assemblage, nature conservation authority CapeNature used rotenone to remove smallmouth bass (Micropterus dolomieu) from the Rondegat River. We investigated whether the rotenone treatments had an adverse impact on the aquatic macroinvertebrate community over the long-term, the first study of its kind in Africa. We monitored macroinvertebrates within treated and untreated (control) sites on multiple sampling events for 2 years before and 2 years after two rotenone treatments. We analysed the difference in invertebrate abundance between treatment and control sites before and after treatment, using generalised linear mixed models with sampling event as a random factor to partition out natural fluctuations in abundances over time.
- Full Text:
- Date Issued: 2019
- Authors: Bellingan, Terence A , Hugo, Sanet , Woodford, Darragh J , Gouws, Jeanne , Villet, Martin H , Weyl, Olaf L F
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/140751 , vital:37915 , DOI: 10.1007/s10750-019-3885-z
- Description: South Africa’s Cape Fold Ecoregion supports a unique freshwater fish assemblage with many endemics. To mitigate impacts of alien invasive fishes on this unique assemblage, nature conservation authority CapeNature used rotenone to remove smallmouth bass (Micropterus dolomieu) from the Rondegat River. We investigated whether the rotenone treatments had an adverse impact on the aquatic macroinvertebrate community over the long-term, the first study of its kind in Africa. We monitored macroinvertebrates within treated and untreated (control) sites on multiple sampling events for 2 years before and 2 years after two rotenone treatments. We analysed the difference in invertebrate abundance between treatment and control sites before and after treatment, using generalised linear mixed models with sampling event as a random factor to partition out natural fluctuations in abundances over time.
- Full Text:
- Date Issued: 2019
Targeted attack detection by means of free and open source solutions
- Authors: Bernardo, Louis F
- Date: 2019
- Subjects: Computer networks -- Security measures , Information technology -- Security measures , Computer security -- Management , Data protection
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/92269 , vital:30703
- Description: Compliance requirements are part of everyday business requirements for various areas, such as retail and medical services. As part of compliance it may be required to have infrastructure in place to monitor the activities in the environment to ensure that the relevant data and environment is sufficiently protected. At the core of such monitoring solutions one would find some type of data repository, or database, to store and ultimately correlate the captured events. Such solutions are commonly called Security Information and Event Management, or SIEM for short. Larger companies have been known to use commercial solutions such as IBM's Qradar, Logrythm, or Splunk. However, these come at significant cost and arent suitable for smaller businesses with limited budgets. These solutions require manual configuration of event correlation for detection of activities that place the environment in danger. This usually requires vendor implementation assistance that also would come at a cost. Alternatively, there are open source solutions that provide the required functionality. This research will demonstrate building an open source solution, with minimal to no cost for hardware or software, while still maintaining the capability of detecting targeted attacks. The solution presented in this research includes Wazuh, which is a combination of OSSEC and the ELK stack, integrated with an Network Intrusion Detection System (NIDS). The success of the integration, is determined by measuring postive attack detection based on each different configuration options. To perform the testing, a deliberately vulnerable platform named Metasploitable will be used as a victim host. The victim host vulnerabilities were created specifically to serve as target for Metasploit. The attacks were generated by utilising Metasploit Framework on a prebuilt Kali Linux host.
- Full Text:
- Date Issued: 2019
- Authors: Bernardo, Louis F
- Date: 2019
- Subjects: Computer networks -- Security measures , Information technology -- Security measures , Computer security -- Management , Data protection
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/92269 , vital:30703
- Description: Compliance requirements are part of everyday business requirements for various areas, such as retail and medical services. As part of compliance it may be required to have infrastructure in place to monitor the activities in the environment to ensure that the relevant data and environment is sufficiently protected. At the core of such monitoring solutions one would find some type of data repository, or database, to store and ultimately correlate the captured events. Such solutions are commonly called Security Information and Event Management, or SIEM for short. Larger companies have been known to use commercial solutions such as IBM's Qradar, Logrythm, or Splunk. However, these come at significant cost and arent suitable for smaller businesses with limited budgets. These solutions require manual configuration of event correlation for detection of activities that place the environment in danger. This usually requires vendor implementation assistance that also would come at a cost. Alternatively, there are open source solutions that provide the required functionality. This research will demonstrate building an open source solution, with minimal to no cost for hardware or software, while still maintaining the capability of detecting targeted attacks. The solution presented in this research includes Wazuh, which is a combination of OSSEC and the ELK stack, integrated with an Network Intrusion Detection System (NIDS). The success of the integration, is determined by measuring postive attack detection based on each different configuration options. To perform the testing, a deliberately vulnerable platform named Metasploitable will be used as a victim host. The victim host vulnerabilities were created specifically to serve as target for Metasploit. The attacks were generated by utilising Metasploit Framework on a prebuilt Kali Linux host.
- Full Text:
- Date Issued: 2019
Quinolone-isoniazid hybrids: Synthesis and preliminary in vitro cytotoxicity and anti-tuberculosis evaluation
- Beteck, Richard M, Seldon, Ronnett, Khanye, Setshaba D, Legoabe, Lesetja J, Hoppe, Heinrich C, Laming, Dustin, Jordaan, Audrey, Warner, Digby F
- Authors: Beteck, Richard M , Seldon, Ronnett , Khanye, Setshaba D , Legoabe, Lesetja J , Hoppe, Heinrich C , Laming, Dustin , Jordaan, Audrey , Warner, Digby F
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/123151 , vital:35410 , https://doi.org/10.1039/C8MD00480C
- Description: Herein, we propose novel quinolones incorporating an INH moiety as potential drug templates against TB. The quinolone-based compounds bearing an INH moiety attached via a hydrazide–hydrazone bond were synthesised and evaluated against Mycobacterium tuberculosis H37Rv (MTB). The compounds were also evaluated for cytotoxicity against HeLa cell lines. These compounds showed significant activity (MIC90) against MTB in the range of 0.2–8 μM without any cytotoxic effects. Compounds 10 (MIC90; 0.9 μM), 11 (MIC90; 0.2 μM), 12 (MIC90; 0.8 μM) and compound 15 (MIC90; 0.8 μM), the most active compounds in this series, demonstrate activities on par with INH and superior to those reported for the fluoroquinolones. The SAR analysis suggests that the nature of substituents at positions −1 and −3 of the quinolone nucleus influences anti-MTB activity. Aqueous solubility evaluation and in vitro metabolic stability of compound 12 highlights favourable drug-like properties for this compound class.
- Full Text:
- Date Issued: 2019
- Authors: Beteck, Richard M , Seldon, Ronnett , Khanye, Setshaba D , Legoabe, Lesetja J , Hoppe, Heinrich C , Laming, Dustin , Jordaan, Audrey , Warner, Digby F
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/123151 , vital:35410 , https://doi.org/10.1039/C8MD00480C
- Description: Herein, we propose novel quinolones incorporating an INH moiety as potential drug templates against TB. The quinolone-based compounds bearing an INH moiety attached via a hydrazide–hydrazone bond were synthesised and evaluated against Mycobacterium tuberculosis H37Rv (MTB). The compounds were also evaluated for cytotoxicity against HeLa cell lines. These compounds showed significant activity (MIC90) against MTB in the range of 0.2–8 μM without any cytotoxic effects. Compounds 10 (MIC90; 0.9 μM), 11 (MIC90; 0.2 μM), 12 (MIC90; 0.8 μM) and compound 15 (MIC90; 0.8 μM), the most active compounds in this series, demonstrate activities on par with INH and superior to those reported for the fluoroquinolones. The SAR analysis suggests that the nature of substituents at positions −1 and −3 of the quinolone nucleus influences anti-MTB activity. Aqueous solubility evaluation and in vitro metabolic stability of compound 12 highlights favourable drug-like properties for this compound class.
- Full Text:
- Date Issued: 2019
In vitro Anti-trypanosomal activities of indanone-based chalcones:
- Beteck, Richard M, Legoabe, Lesetje J, Isaacs, Michelle, Hoppe, Heinrich C
- Authors: Beteck, Richard M , Legoabe, Lesetje J , Isaacs, Michelle , Hoppe, Heinrich C
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158280 , vital:40169 , https://doi.org/10.3354/meps12953
- Description: Human African trypanosomiasis is a neglected infectious disease that affects mostly people living in the rural areas of Africa. Current treatment options are limited to just four drugs that have been in use of four to nine decades. The life-threatening toxic side-effects associated with the use of these drugs are disconcerting. Poor efficacy, low oral bioavailability, and high cost are other shortcomings of current HAT treatments. Evaluating the potentials of known hits for other therapeutic areas may be a fast and convenient method to discover new hit compounds against alternative targets. A library of 34 known indanone based chalcones was screened against T.b. brucei and nine potent hits, having IC50 values between 0.5–8.9 µM, were found. The SAR studies of this series could provide useful information in guiding future exploration of this class of compounds in search of more potent, safe, and low cost anti-trypanosomal agents.
- Full Text:
- Date Issued: 2019
- Authors: Beteck, Richard M , Legoabe, Lesetje J , Isaacs, Michelle , Hoppe, Heinrich C
- Date: 2019
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/158280 , vital:40169 , https://doi.org/10.3354/meps12953
- Description: Human African trypanosomiasis is a neglected infectious disease that affects mostly people living in the rural areas of Africa. Current treatment options are limited to just four drugs that have been in use of four to nine decades. The life-threatening toxic side-effects associated with the use of these drugs are disconcerting. Poor efficacy, low oral bioavailability, and high cost are other shortcomings of current HAT treatments. Evaluating the potentials of known hits for other therapeutic areas may be a fast and convenient method to discover new hit compounds against alternative targets. A library of 34 known indanone based chalcones was screened against T.b. brucei and nine potent hits, having IC50 values between 0.5–8.9 µM, were found. The SAR studies of this series could provide useful information in guiding future exploration of this class of compounds in search of more potent, safe, and low cost anti-trypanosomal agents.
- Full Text:
- Date Issued: 2019
Narratives and home: remembering an almost forgotten walk
- Bezuidenhout, Natasha Belinda
- Authors: Bezuidenhout, Natasha Belinda
- Date: 2019
- Subjects: Home in literature , Home in art , Artists -- South Africa
- Language: English
- Type: text , Thesis , Masters , MFA
- Identifier: http://hdl.handle.net/10962/115039 , vital:34072
- Description: The title of my exhibition Bittersoet alludes to the self-exploratory nature of my practice, as I interrogate the personal memories associated with objects that characterise the relationship between myself and my mother (mamma). This supporting document, Narratives and Home: Remembering an almost forgotten walk, considers the key conceptual concerns informing my practice. In this mini-thesis, I address the question: ‘What is a home?’. Drawing from my own Fine Art Practice, I explore how home can be examined as a product of the imagination, rather than only as a physical place. I consider how ‘home’ is constructed as the primary objective within an ideological framework defined by history, memory and narrative. Engaging beyond the idea of ‘home’ as a fixed structure or place, I examine the idea of ‘home’ as something fluid that is negotiated and defined by the interaction between objects and language. It is concerned with dialectics of memory and narrative as they pertain directly to an experience of both searching for and reimagining home through metaphorical representations. In particular, I explore how home can be seen as equally familiar and unfamiliar, existing in-between, always changing, never fixed, rather in a constant state of flux. The concept of home is addressed in a dialogical process by using Afrikaans as my mother tongue, I narrate informal conversations between myself and my mother. These conversations transform and expand into hybrid words, memories and narratives to form a layered continuous dialogue between my practice and research. This notion relates to exploring oneself and the ‘fictions’ of the past. The self being fundamental to the individual comprehension of both ‘place’ and ‘space’.
- Full Text:
- Date Issued: 2019
- Authors: Bezuidenhout, Natasha Belinda
- Date: 2019
- Subjects: Home in literature , Home in art , Artists -- South Africa
- Language: English
- Type: text , Thesis , Masters , MFA
- Identifier: http://hdl.handle.net/10962/115039 , vital:34072
- Description: The title of my exhibition Bittersoet alludes to the self-exploratory nature of my practice, as I interrogate the personal memories associated with objects that characterise the relationship between myself and my mother (mamma). This supporting document, Narratives and Home: Remembering an almost forgotten walk, considers the key conceptual concerns informing my practice. In this mini-thesis, I address the question: ‘What is a home?’. Drawing from my own Fine Art Practice, I explore how home can be examined as a product of the imagination, rather than only as a physical place. I consider how ‘home’ is constructed as the primary objective within an ideological framework defined by history, memory and narrative. Engaging beyond the idea of ‘home’ as a fixed structure or place, I examine the idea of ‘home’ as something fluid that is negotiated and defined by the interaction between objects and language. It is concerned with dialectics of memory and narrative as they pertain directly to an experience of both searching for and reimagining home through metaphorical representations. In particular, I explore how home can be seen as equally familiar and unfamiliar, existing in-between, always changing, never fixed, rather in a constant state of flux. The concept of home is addressed in a dialogical process by using Afrikaans as my mother tongue, I narrate informal conversations between myself and my mother. These conversations transform and expand into hybrid words, memories and narratives to form a layered continuous dialogue between my practice and research. This notion relates to exploring oneself and the ‘fictions’ of the past. The self being fundamental to the individual comprehension of both ‘place’ and ‘space’.
- Full Text:
- Date Issued: 2019