"NSFAS no secure future as students"
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8054 , http://hdl.handle.net/10962/d10205512
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8054 , http://hdl.handle.net/10962/d10205512
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
"Blade is blunt"
- Authors: Thomas, Cornelius
- Date: 2015
- Language: English
- Type: still image
- Identifier: vital:7963 , http://hdl.handle.net/10962/d1020436
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Language: English
- Type: still image
- Identifier: vital:7963 , http://hdl.handle.net/10962/d1020436
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Getting down to toyi-toyi
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8052 , http://hdl.handle.net/10962/d1020548
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8052 , http://hdl.handle.net/10962/d1020548
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Dr Michael Rogan and Megan Reuvers
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8050 , http://hdl.handle.net/10962/d1020546
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8050 , http://hdl.handle.net/10962/d1020546
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Dr Sizwe Mabizela joining in the singing
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8051 , http://hdl.handle.net/10962/d1020547
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8051 , http://hdl.handle.net/10962/d1020547
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Sitting waiting
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8059 , http://hdl.handle.net/10962/d1020556
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8059 , http://hdl.handle.net/10962/d1020556
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Prof Larry Strelitz
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8056 , http://hdl.handle.net/10962/d1020553
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8056 , http://hdl.handle.net/10962/d1020553
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
"Reduce the fees"
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8058 , http://hdl.handle.net/10962/d1020555
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8058 , http://hdl.handle.net/10962/d1020555
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
End of the march
- Authors: Thomas, Cornelius
- Date: 2015
- Language: English
- Type: still image
- Identifier: vital:7981 , http://hdl.handle.net/10962/d1020456
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Language: English
- Type: still image
- Identifier: vital:7981 , http://hdl.handle.net/10962/d1020456
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
"Peace love education"
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8055 , http://hdl.handle.net/10962/d1020552
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8055 , http://hdl.handle.net/10962/d1020552
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
The registrar Dr Steve Fourie addressing the students, 21 Oct 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8060 , http://hdl.handle.net/10962/d1020557
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8060 , http://hdl.handle.net/10962/d1020557
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Higher education is underfunded
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8053 , http://hdl.handle.net/10962/d1020549
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
- Authors: Thomas, Cornelius
- Date: 2015
- Type: Image
- Identifier: vital:8053 , http://hdl.handle.net/10962/d1020549
- Description: On Wednesday, 21 October 2015, Rhodes University closed in solidarity with the higher education sector as students and staff embarked on nationwide protest action against the shortage of funding in the South African higher education sector. #FeesMustFall is a national student led protest movement that began in mid-October 2015 in response to proposed increases in fees at South African universities. These images depict the peaceful march and illustrate the extent of solidarity among staff, students and community members who joined in support of the protest.
- Full Text: false
- Date Issued: 2015
Nkwali, Intlombe (Senior Gqhirha dancing)
- Authors: Senior Gqhirha
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219588 , vital:48538 , KHP-169
- Description: Senior Gqhirha dancing , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
- Authors: Senior Gqhirha
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219588 , vital:48538 , KHP-169
- Description: Senior Gqhirha dancing , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
Nkwali, Intlombe (Senior Gqhirha dancing)
- Authors: Senior Gqhirha
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219579 , vital:48536 , KHP-169
- Description: Senior Gqhirha dancing , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
- Authors: Senior Gqhirha
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219579 , vital:48536 , KHP-169
- Description: Senior Gqhirha dancing , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
Shadow of the Sun – the distribution of wellbeing in Sub-Saharan Africa
- Roberts, Benjamin J, Gordon, Steven Lawrence, Moller, Valerie, Struwig, Jare
- Authors: Roberts, Benjamin J , Gordon, Steven Lawrence , Moller, Valerie , Struwig, Jare
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/67235 , vital:29062 , https://doi.org/10.1007/978-94-017-9178-6_23
- Description: publisher version , Despite the enthusiasm that prevailed during sub-Saharan Africa’s initial wave of independence, representations of quality of life in the region over the last half-century focused on themes that typically characterize failed states: maladministration, violence and conflict, disease, impoverishment and suffering. Although considerable hardship persists, the subcontinent experienced impressive economic growth over the last decade. This, together with increasing gains from state-led social spending, has prompted a new narrative that speaks of promise and opportunity. Against this backdrop, the chapter reviews quality of life in the region using select objective and subjective wellbeing measures. The results confirm the general pattern of recent social progress, though lingering deprivation, inequality and often difficult political conditions. While this situation is reflected in relatively low life satisfaction evaluations, it is also accompanied by a resolute optimism that attests to the resilience of the region’s citizens in the face of adversity. The chapter also assesses the influence of certain objective conditions on subjective wellbeing at the macro-level.
- Full Text: false
- Date Issued: 2015
- Authors: Roberts, Benjamin J , Gordon, Steven Lawrence , Moller, Valerie , Struwig, Jare
- Date: 2015
- Language: English
- Type: text , book
- Identifier: http://hdl.handle.net/10962/67235 , vital:29062 , https://doi.org/10.1007/978-94-017-9178-6_23
- Description: publisher version , Despite the enthusiasm that prevailed during sub-Saharan Africa’s initial wave of independence, representations of quality of life in the region over the last half-century focused on themes that typically characterize failed states: maladministration, violence and conflict, disease, impoverishment and suffering. Although considerable hardship persists, the subcontinent experienced impressive economic growth over the last decade. This, together with increasing gains from state-led social spending, has prompted a new narrative that speaks of promise and opportunity. Against this backdrop, the chapter reviews quality of life in the region using select objective and subjective wellbeing measures. The results confirm the general pattern of recent social progress, though lingering deprivation, inequality and often difficult political conditions. While this situation is reflected in relatively low life satisfaction evaluations, it is also accompanied by a resolute optimism that attests to the resilience of the region’s citizens in the face of adversity. The chapter also assesses the influence of certain objective conditions on subjective wellbeing at the macro-level.
- Full Text: false
- Date Issued: 2015
The natural history and conservation of Indian Ocean Humpback Dolphins (Sousa plumbea) in South African waters
- Plön, Stephanie, Cockcroft, Victor G, Froneman, P William
- Authors: Plön, Stephanie , Cockcroft, Victor G , Froneman, P William
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/68207 , vital:29219 , https://doi.org/10.1016/bs.amb.2015.08.005
- Description: Publisher version , Although most knowledge on the biology of Sousa plumbea has primarily come from South African waters, a number of research gaps remain on the natural history and status of the species in the region. Research on two populations in South African waters for which some historical data exist may aid in highlighting long-term changes in the biology and natural history of this little known coastal delphinid. Recent studies on the age, growth and reproduction of animals incidentally caught in shark nets in Richards Bay, KwaZulu-Natal, yielded a lower maximum age estimate of 24 (previously 46) growth-layer-groups (GLGs), sexual maturity of 7.5 and 8 GLGs in males and females (previously 12–13 and 10 GLGs, respectively), an ovulation rate of 0.2 and a 5-year calving interval (previously 0.3 and 3-year calving interval) than previously reported. These differences may be due to a difference in the interpretation of GLGs between observers or a predominance of young males being caught in the shark nets. Stomach content analysis revealed a change in the relative proportions of the main prey items over the past 25 years, but no difference in species richness or diversity was found between the sexes. No change in trophic level was recorded between 1972 and 2009. Field studies in Algoa Bay, Eastern Cape, conducted 16 years apart indicated a decline in the mean group size (from 7 to 3 animals), a decline in the maximum group size (from 24 to 13 animals), an increase in solitary individuals (15.4–36%), and a change in behaviour from predominantly foraging (64–18%) to mainly travelling (24–49%). The observed changes are suggestive of a change in food availability, resulting in a range shift or a potential decline in numbers. These studies indicate the importance of long-term studies to monitor population changes and their possible causes. A number of threats, such as shark nets, pollution (noise and chemical), and coastal development and disturbance, to the humpback dolphin populations in South Africa have been identified. Urgent action is required to ensure continued existence of the species in South African waters.
- Full Text: false
- Date Issued: 2015
- Authors: Plön, Stephanie , Cockcroft, Victor G , Froneman, P William
- Date: 2015
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/68207 , vital:29219 , https://doi.org/10.1016/bs.amb.2015.08.005
- Description: Publisher version , Although most knowledge on the biology of Sousa plumbea has primarily come from South African waters, a number of research gaps remain on the natural history and status of the species in the region. Research on two populations in South African waters for which some historical data exist may aid in highlighting long-term changes in the biology and natural history of this little known coastal delphinid. Recent studies on the age, growth and reproduction of animals incidentally caught in shark nets in Richards Bay, KwaZulu-Natal, yielded a lower maximum age estimate of 24 (previously 46) growth-layer-groups (GLGs), sexual maturity of 7.5 and 8 GLGs in males and females (previously 12–13 and 10 GLGs, respectively), an ovulation rate of 0.2 and a 5-year calving interval (previously 0.3 and 3-year calving interval) than previously reported. These differences may be due to a difference in the interpretation of GLGs between observers or a predominance of young males being caught in the shark nets. Stomach content analysis revealed a change in the relative proportions of the main prey items over the past 25 years, but no difference in species richness or diversity was found between the sexes. No change in trophic level was recorded between 1972 and 2009. Field studies in Algoa Bay, Eastern Cape, conducted 16 years apart indicated a decline in the mean group size (from 7 to 3 animals), a decline in the maximum group size (from 24 to 13 animals), an increase in solitary individuals (15.4–36%), and a change in behaviour from predominantly foraging (64–18%) to mainly travelling (24–49%). The observed changes are suggestive of a change in food availability, resulting in a range shift or a potential decline in numbers. These studies indicate the importance of long-term studies to monitor population changes and their possible causes. A number of threats, such as shark nets, pollution (noise and chemical), and coastal development and disturbance, to the humpback dolphin populations in South Africa have been identified. Urgent action is required to ensure continued existence of the species in South African waters.
- Full Text: false
- Date Issued: 2015
Hsp40 Co-chaperones as drug targets: towards the development of specific inhibitors
- Pesce, Eva-Rachele, Blatch, Gregory L, Edkins, Adrienne L
- Authors: Pesce, Eva-Rachele , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66335 , vital:28937 , https://doi.org/10.1007/7355_2015_92
- Description: publisher version , The heat shock protein 40 (Hsp40/DNAJ) family of co-chaperones modulates the activity of the major molecular chaperone heat shock protein 70 (Hsp70) protein group. Hsp40 stimulates the basal ATPase activity of Hsp70 and hence regulates the affinity of Hsp70 for substrate proteins. The number of Hsp40 genes in most organisms is substantially greater than the number of Hsp70 genes. Therefore, different Hsp40 family members may regulate different activities of the same Hsp70. This fact, along with increasing knowledge of the function of Hsp40 in diseases, has led to certain Hsp40 isoforms being considered promising drug targets. Here we review the role of Hsp40 in human disease and recent developments towards the creation of Hsp40-specific inhibitors.
- Full Text: false
- Date Issued: 2016
- Authors: Pesce, Eva-Rachele , Blatch, Gregory L , Edkins, Adrienne L
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/66335 , vital:28937 , https://doi.org/10.1007/7355_2015_92
- Description: publisher version , The heat shock protein 40 (Hsp40/DNAJ) family of co-chaperones modulates the activity of the major molecular chaperone heat shock protein 70 (Hsp70) protein group. Hsp40 stimulates the basal ATPase activity of Hsp70 and hence regulates the affinity of Hsp70 for substrate proteins. The number of Hsp40 genes in most organisms is substantially greater than the number of Hsp70 genes. Therefore, different Hsp40 family members may regulate different activities of the same Hsp70. This fact, along with increasing knowledge of the function of Hsp40 in diseases, has led to certain Hsp40 isoforms being considered promising drug targets. Here we review the role of Hsp40 in human disease and recent developments towards the creation of Hsp40-specific inhibitors.
- Full Text: false
- Date Issued: 2016
SCENIC VIEW 3
- Authors: No performer
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219499 , vital:48529 , KHP-165
- Description: SCENIC VIEW , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
- Authors: No performer
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219499 , vital:48529 , KHP-165
- Description: SCENIC VIEW , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
SCENIC VIEW 2
- Authors: No performer
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219489 , vital:48527 , KHP-165
- Description: SCENIC VIEW , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
- Authors: No performer
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219489 , vital:48527 , KHP-165
- Description: SCENIC VIEW , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
OUTDOOR 1
- Authors: No performer
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219451 , vital:48522 , KHP-163
- Description: KWATHOLE PICTURE OF THE OUTDOOR , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015
- Authors: No performer
- Date: 2015
- Subjects: UNCATALOGUED
- Type: Image
- Identifier: http://hdl.handle.net/10962/219451 , vital:48522 , KHP-163
- Description: KWATHOLE PICTURE OF THE OUTDOOR , Use of this resource is governed by the terms and conditions of the Creative Commons "Attribution-NonCommercial-ShareAlike" License (http://creativecommons.org/licenses/by-nc-sa/2.0/) (NEVER CAHNGE THIS FIELD)
- Full Text: false
- Date Issued: 2015