Impact of a visual skills training program on visual performance of cricket fielders
- Authors: Bonnesse, Matthew Gregory
- Date: 2016
- Subjects: Cricket -- Training , Cricket players Cricket. Vision
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/7733 , vital:23440
- Description: The primary aim of this study was to determine whether a cricket specific visual skills training program has an impact on the visual performance of cricket fielders. The specific visual skills included accommodation, visual memory, speed of recognition, peripheral awareness, hand-eye coordination and saccadic eye movement. The study was exploratory and true-experimental in nature and utilized a quantitative approach. The pretest-posttest randomized group design was used. A total number of 20 participants that met the inclusion criteria were included in the study by means of purposive sampling. The 20 participants were randomly assigned to control (n=10) and experimental (n=10) groups. The experimental group underwent six-weeks of visual skills training. The tests used consisted of the Accumulator, Evasion, Corner Stretch and Flash tests on the Batak Pro, Hand-eye-coordination test, Hart Near Far Rock Chart and a Saccadic eye movement chart. Differences between the pre- and post-test scores were all positive and statistically (p<0.05) and practically (d>0.2) significant for the experimental group for the following visual skills tests: Hart Chart (M=7.90±3.73), Saccadic Chart (M=17.50±9.58), Accumulator (M=19.60±5.13), Corner Stretch (M=10.50±9.56) and Flash (M=5.40±3.75). The Evasion test (M=17.50±25.67) also showed a positive but insignificant improvement from pre- to post-test for the experimental group. The control group did not show any statistically significant improvements from pre- to post-test except in the case of Hart Chart (M=3.00±2.16) and Accumulator (M=2.40±2.55). Overall the experimental group produced significantly larger (p<0.05, d>0.20) pre- to post-test mean differences than the control group for six of the seven tests implemented. The Ball Toss test which was one of three hand-eye coordination tests did not show any significant differences between experimental and control groups even though the experimental group produced larger improvements. The other two tests that assessed hand-eye coordination (Accumulator and Corner Stretch) did, however reflect significant improvements for the experimental group. The findings of this study therefore revealed that improvements in visual skill performance of cricket players can be achieved through specific training.
- Full Text:
- Date Issued: 2016
- Authors: Bonnesse, Matthew Gregory
- Date: 2016
- Subjects: Cricket -- Training , Cricket players Cricket. Vision
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/7733 , vital:23440
- Description: The primary aim of this study was to determine whether a cricket specific visual skills training program has an impact on the visual performance of cricket fielders. The specific visual skills included accommodation, visual memory, speed of recognition, peripheral awareness, hand-eye coordination and saccadic eye movement. The study was exploratory and true-experimental in nature and utilized a quantitative approach. The pretest-posttest randomized group design was used. A total number of 20 participants that met the inclusion criteria were included in the study by means of purposive sampling. The 20 participants were randomly assigned to control (n=10) and experimental (n=10) groups. The experimental group underwent six-weeks of visual skills training. The tests used consisted of the Accumulator, Evasion, Corner Stretch and Flash tests on the Batak Pro, Hand-eye-coordination test, Hart Near Far Rock Chart and a Saccadic eye movement chart. Differences between the pre- and post-test scores were all positive and statistically (p<0.05) and practically (d>0.2) significant for the experimental group for the following visual skills tests: Hart Chart (M=7.90±3.73), Saccadic Chart (M=17.50±9.58), Accumulator (M=19.60±5.13), Corner Stretch (M=10.50±9.56) and Flash (M=5.40±3.75). The Evasion test (M=17.50±25.67) also showed a positive but insignificant improvement from pre- to post-test for the experimental group. The control group did not show any statistically significant improvements from pre- to post-test except in the case of Hart Chart (M=3.00±2.16) and Accumulator (M=2.40±2.55). Overall the experimental group produced significantly larger (p<0.05, d>0.20) pre- to post-test mean differences than the control group for six of the seven tests implemented. The Ball Toss test which was one of three hand-eye coordination tests did not show any significant differences between experimental and control groups even though the experimental group produced larger improvements. The other two tests that assessed hand-eye coordination (Accumulator and Corner Stretch) did, however reflect significant improvements for the experimental group. The findings of this study therefore revealed that improvements in visual skill performance of cricket players can be achieved through specific training.
- Full Text:
- Date Issued: 2016
Counting on demographic equity to transform institutional cultures at historically white South African universities?:
- Booi, Masixole, Vincent, Louise, Liccardo, Sabrina
- Authors: Booi, Masixole , Vincent, Louise , Liccardo, Sabrina
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141946 , vital:38018 , DOI: 10.1080/07294360.2017.1289155
- Description: The post-apartheid higher education transformation project is faced with the challenge of recruiting and retaining black academics and other senior staff. But when we shift the focus from participation rates to equality–inequality within historically white universities (HWUs), then the discourse changes from demographic equity and redress to institutional culture and diversity. HWUs invoke the need to maintain their position as leading higher education institutions globally, and notions of ‘quality’ and ‘excellence’ have emerged as discursive practices, which serve to perpetuate exclusion. The question then arises as to which forms of capital comprise the Gold Standard at HWUs? Several South African universities have responded to the challenge of recruiting and retaining black academics by initiating programmes for the ‘accelerated development’ of these candidates.
- Full Text:
- Date Issued: 2017
- Authors: Booi, Masixole , Vincent, Louise , Liccardo, Sabrina
- Date: 2017
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/141946 , vital:38018 , DOI: 10.1080/07294360.2017.1289155
- Description: The post-apartheid higher education transformation project is faced with the challenge of recruiting and retaining black academics and other senior staff. But when we shift the focus from participation rates to equality–inequality within historically white universities (HWUs), then the discourse changes from demographic equity and redress to institutional culture and diversity. HWUs invoke the need to maintain their position as leading higher education institutions globally, and notions of ‘quality’ and ‘excellence’ have emerged as discursive practices, which serve to perpetuate exclusion. The question then arises as to which forms of capital comprise the Gold Standard at HWUs? Several South African universities have responded to the challenge of recruiting and retaining black academics by initiating programmes for the ‘accelerated development’ of these candidates.
- Full Text:
- Date Issued: 2017
Accelerated development programmes for Black academics: Interrupting or reproducing social and cultural dominance?
- Authors: Booi, Masixole
- Date: 2016
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/3338 , vital:20483
- Description: A wide body of research literature on transformation of higher education institutions in South Africa has focused on institutional reform and restructuring, change in employment legislation and policies, transforming institutional culture(s) and student and staff demographics (Portnoi, 2009:373; Viljoen and Rothmann, 2002:3; Badat, 2007; 2010; Cloete, Muller, Makgoba and Ekong, 1997; Nieman, 2010). The literature on transformation of higher education institutions shows that the underrepresentation, recruiting and retaining of blacks and women in senior posts is still the major challenge faced by the project of transforming higher education, particularly in Historically White Institutions (HWIs). Universities have introduced a variety of ‘accelerated development’ programmes to meet this challenge and accelerate the entry into academia of black academics. The present study draws on Pierre Bourdieu’s notions of cultural capital, field and social capital to interpret the lived experiences of participants in the Accelerated Development Programme (ADP) of one HWI. In particular the study is interested in how, in the participants’ experience, they, as members of the programme, have or have not been able to contribute to the transformation of the culture(s) of the institution. The study critically examines the assumption that the institutional practices, values and norms can be changed only by socialising ‘new’ lecturers into an already existing dominant culture rather than seeing the need to socialise existing lecturers into a new culture informed by a democratic ethos.
- Full Text:
- Date Issued: 2016
- Authors: Booi, Masixole
- Date: 2016
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/3338 , vital:20483
- Description: A wide body of research literature on transformation of higher education institutions in South Africa has focused on institutional reform and restructuring, change in employment legislation and policies, transforming institutional culture(s) and student and staff demographics (Portnoi, 2009:373; Viljoen and Rothmann, 2002:3; Badat, 2007; 2010; Cloete, Muller, Makgoba and Ekong, 1997; Nieman, 2010). The literature on transformation of higher education institutions shows that the underrepresentation, recruiting and retaining of blacks and women in senior posts is still the major challenge faced by the project of transforming higher education, particularly in Historically White Institutions (HWIs). Universities have introduced a variety of ‘accelerated development’ programmes to meet this challenge and accelerate the entry into academia of black academics. The present study draws on Pierre Bourdieu’s notions of cultural capital, field and social capital to interpret the lived experiences of participants in the Accelerated Development Programme (ADP) of one HWI. In particular the study is interested in how, in the participants’ experience, they, as members of the programme, have or have not been able to contribute to the transformation of the culture(s) of the institution. The study critically examines the assumption that the institutional practices, values and norms can be changed only by socialising ‘new’ lecturers into an already existing dominant culture rather than seeing the need to socialise existing lecturers into a new culture informed by a democratic ethos.
- Full Text:
- Date Issued: 2016
Creating evidence-based guidelines for healthy eating educational campaigns aimed at low-income South Africans: a case study of Grahamstown
- Authors: Booth, Christopher
- Date: 2016
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/3336 , vital:20485
- Description: Through a literature review and qualitative research, this study explores what a media-centric nutritional intervention needs to include in order to be effective amongst those whose health is most impacted by poor nutrition – poorer and mostly black South Africans. The study sketches the current nutritional landscape of South Africa, and draws on both Behaviour Change Communication and Media Effect theories to hypothesise how a campaign might be devised to change popular understandings of the relationship between health and nutrition, and inspire some change in food consumption behaviours and choices. The study explores the key factors that drive nutritional behaviours (including the environmental constraint of cost, the peer pressure and socialisation of food, and the desire for knowledge and change) and explores how media-based interventions could be more effective. To do this, this study creates three layers of an idealised and hypothetical “Super 7” fruit and vegetable consumption promotion campaign. From this data, and the insights developed, new guidelines for possible future nutritional education campaigns are suggested and developed.
- Full Text:
- Date Issued: 2016
- Authors: Booth, Christopher
- Date: 2016
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/3336 , vital:20485
- Description: Through a literature review and qualitative research, this study explores what a media-centric nutritional intervention needs to include in order to be effective amongst those whose health is most impacted by poor nutrition – poorer and mostly black South Africans. The study sketches the current nutritional landscape of South Africa, and draws on both Behaviour Change Communication and Media Effect theories to hypothesise how a campaign might be devised to change popular understandings of the relationship between health and nutrition, and inspire some change in food consumption behaviours and choices. The study explores the key factors that drive nutritional behaviours (including the environmental constraint of cost, the peer pressure and socialisation of food, and the desire for knowledge and change) and explores how media-based interventions could be more effective. To do this, this study creates three layers of an idealised and hypothetical “Super 7” fruit and vegetable consumption promotion campaign. From this data, and the insights developed, new guidelines for possible future nutritional education campaigns are suggested and developed.
- Full Text:
- Date Issued: 2016
A proposed Christian-based governing model to increase the success of entrepreneurial ventures in South Africa
- Authors: Boshoff, Leslie Ian
- Date: 2016
- Subjects: Entrepreneurship -- South Africa , Success in business -- South Africa , Business -- Religious aspects , Sustainable development -- South Africa
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: http://hdl.handle.net/10948/4827 , vital:20712
- Description: The Republic of South Africa (RSA) became a democracy when the African National Congress (ANC) came to power in 1994. However, more than twenty years after the apartheid era, the people of the RSA are highly politicised and society still shows an extremely high level of inequality in income that is aggravated by the lack of formal job opportunities in the country. Disturbingly, early-stage entrepreneurial activity in the RSA declined from 7.8 percent in 2008 to 5 percent in 2009. As a result, the low levels of entrepreneurial activity are partly responsible for the stagnation in the structural transformation of the economy. The economy remains dependent on sectors such as agriculture and mining where looting, instability, violence and rent-seeking are endemic in spite of plentiful natural resources. As a consequence of these factors, manufacturing is becoming increasingly uncompetitive and the economy is becoming increasingly less innovative. The RSA‟s government leaders should have used the strengths of the country to minimise or rectify the weaknesses of the extremely high levels of inequality in income and the lack of formal job opportunities. Instead, these leaders identified their supporters, satisfied their short-term consumption demands, distributed jobs to the party faithful and provided social welfare to the poor. Additionally, the majority of school leavers are not pursuing tertiary studies but, with limited or little education, they still have to form part of the potential labour force of the future. The youth employment rate for 15 to 24 year-olds, in the RSA, is as low as 12.5 percent. Again, this highlights the importance of finding alternative ways to increase the population‟s participation in the economy, probably through some form of entrepreneurship. The purpose of this study was to develop a theoretical model with the main objective being to identify the factors (variables) that will promote growth, sustainability and good governance in Christian-owned Small, Micro and Medium Enterprises (SMME) within the RSA. Business is commonly viewed as a secular pursuit and religious people, particularly in Western societies, have a narrow view of the conceptual and practical application of their faith and spirituality in their businesses. As a result, the potential of businesses to influence communities, particularly with regard to issues such as social iniquities and cultural reform, good governance, responsible business behaviour, social capital, spiritual intelligence (SQ) and Christian entrepreneurship orientation appear to be, at worst, more or less irrelevant and, at best, greatly under-valued and under-utilised. The intersection of these constructs provides an understanding of how an entrepreneur‟s heightened consciousness in terms of his/her personal values and beliefs can affect his or her business activities and crucial characteristics of the entrepreneurial process, such as the recognition of opportunities, the creation of new ventures, as well as the operation and growth of these business ventures. This study uncovered a number of themes that shed light on how Christian SMME owner-managers rationalise the everyday dealings of their business lives as an expression of their faith. This study is an expression of a complex phenomenon that is extremely relevant in the present day and sharpens the focus on the important role that religious faith has to play in the field of business outcomes. Many Christian entrepreneurs express a motivational need to give back to their communities, customers and other stakeholders of the business venture. Christian entrepreneurs value intrinsic factors like purpose, passionate work and personal calling above wealth, fame, power, money, and recognition. A combination of Christian character traits forms the backbone of a Christian‟s internal power and purpose. God created people to glorify Him and this purpose is achieved through the fulfilling of a personal calling. A calling is often accompanied by a conviction of divine influence and the vocation in which one customarily engages. The call to the Christian entrepreneur is to be the salt and light in an environment (Mathew 5:13) like RSA, that is not conducive to entrepreneurial behaviour, where unemployment is very high, infrastructure is buckling under the pressures of bad management and corruption is rife.
- Full Text:
- Date Issued: 2016
- Authors: Boshoff, Leslie Ian
- Date: 2016
- Subjects: Entrepreneurship -- South Africa , Success in business -- South Africa , Business -- Religious aspects , Sustainable development -- South Africa
- Language: English
- Type: Thesis , Doctoral , DBA
- Identifier: http://hdl.handle.net/10948/4827 , vital:20712
- Description: The Republic of South Africa (RSA) became a democracy when the African National Congress (ANC) came to power in 1994. However, more than twenty years after the apartheid era, the people of the RSA are highly politicised and society still shows an extremely high level of inequality in income that is aggravated by the lack of formal job opportunities in the country. Disturbingly, early-stage entrepreneurial activity in the RSA declined from 7.8 percent in 2008 to 5 percent in 2009. As a result, the low levels of entrepreneurial activity are partly responsible for the stagnation in the structural transformation of the economy. The economy remains dependent on sectors such as agriculture and mining where looting, instability, violence and rent-seeking are endemic in spite of plentiful natural resources. As a consequence of these factors, manufacturing is becoming increasingly uncompetitive and the economy is becoming increasingly less innovative. The RSA‟s government leaders should have used the strengths of the country to minimise or rectify the weaknesses of the extremely high levels of inequality in income and the lack of formal job opportunities. Instead, these leaders identified their supporters, satisfied their short-term consumption demands, distributed jobs to the party faithful and provided social welfare to the poor. Additionally, the majority of school leavers are not pursuing tertiary studies but, with limited or little education, they still have to form part of the potential labour force of the future. The youth employment rate for 15 to 24 year-olds, in the RSA, is as low as 12.5 percent. Again, this highlights the importance of finding alternative ways to increase the population‟s participation in the economy, probably through some form of entrepreneurship. The purpose of this study was to develop a theoretical model with the main objective being to identify the factors (variables) that will promote growth, sustainability and good governance in Christian-owned Small, Micro and Medium Enterprises (SMME) within the RSA. Business is commonly viewed as a secular pursuit and religious people, particularly in Western societies, have a narrow view of the conceptual and practical application of their faith and spirituality in their businesses. As a result, the potential of businesses to influence communities, particularly with regard to issues such as social iniquities and cultural reform, good governance, responsible business behaviour, social capital, spiritual intelligence (SQ) and Christian entrepreneurship orientation appear to be, at worst, more or less irrelevant and, at best, greatly under-valued and under-utilised. The intersection of these constructs provides an understanding of how an entrepreneur‟s heightened consciousness in terms of his/her personal values and beliefs can affect his or her business activities and crucial characteristics of the entrepreneurial process, such as the recognition of opportunities, the creation of new ventures, as well as the operation and growth of these business ventures. This study uncovered a number of themes that shed light on how Christian SMME owner-managers rationalise the everyday dealings of their business lives as an expression of their faith. This study is an expression of a complex phenomenon that is extremely relevant in the present day and sharpens the focus on the important role that religious faith has to play in the field of business outcomes. Many Christian entrepreneurs express a motivational need to give back to their communities, customers and other stakeholders of the business venture. Christian entrepreneurs value intrinsic factors like purpose, passionate work and personal calling above wealth, fame, power, money, and recognition. A combination of Christian character traits forms the backbone of a Christian‟s internal power and purpose. God created people to glorify Him and this purpose is achieved through the fulfilling of a personal calling. A calling is often accompanied by a conviction of divine influence and the vocation in which one customarily engages. The call to the Christian entrepreneur is to be the salt and light in an environment (Mathew 5:13) like RSA, that is not conducive to entrepreneurial behaviour, where unemployment is very high, infrastructure is buckling under the pressures of bad management and corruption is rife.
- Full Text:
- Date Issued: 2016
The experiences of older persons and their adult children on maintaining positive parent-child relationships
- Authors: Boshoff, Marcelle Dianne
- Date: 2016
- Subjects: Parent and adult child , Fammilies -- Psychological aspects , Adult children -- Psychology
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/4631 , vital:20624
- Description: The incidence of increased life span as well as a lack of care for older persons, gave rise to the South African Older persons Act (Act No 13 of 2006), which guides society in how our older persons should be treated. This Act also provides a clear indication of the expectations of caring for older persons within communities and families. Many older persons people rely on the relationships they have with their children in their golden years, to be fulfilling and loving. This study therefore aimed to explore the experiences of older persons and their adult children on maintaining positive relationships in order for the relationship to be most beneficial for both older persons and their adult children. The quality of relationships between adult children and older persons according to Newby (2010) can ease participation of adult children in the lives of older persons. This study was conducted from a qualitative research perspective that is exploratory, descriptive and contextual in nature. The exploratory-descriptive design allowed the researcher to understand the topic by using a narrative strategy of inquiry. A non-probability purposive sampling method was applied to identify five older persons as well as the adult children of these older persons who are retirees of an automotive company in South Africa. Individual, semi-structured face to face interviews were conducted with older persons as well as with at least one of their adult children who did not reside with them. Thematic data analysis technique was used to analyse the data collected. The study is viewed as significant in enhancing the understanding of satisfying and caring relationships between older persons and their adult children in order to add to the body of existing knowledge in social gerontology and to improve direct social work practice with older persons.
- Full Text:
- Date Issued: 2016
- Authors: Boshoff, Marcelle Dianne
- Date: 2016
- Subjects: Parent and adult child , Fammilies -- Psychological aspects , Adult children -- Psychology
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/4631 , vital:20624
- Description: The incidence of increased life span as well as a lack of care for older persons, gave rise to the South African Older persons Act (Act No 13 of 2006), which guides society in how our older persons should be treated. This Act also provides a clear indication of the expectations of caring for older persons within communities and families. Many older persons people rely on the relationships they have with their children in their golden years, to be fulfilling and loving. This study therefore aimed to explore the experiences of older persons and their adult children on maintaining positive relationships in order for the relationship to be most beneficial for both older persons and their adult children. The quality of relationships between adult children and older persons according to Newby (2010) can ease participation of adult children in the lives of older persons. This study was conducted from a qualitative research perspective that is exploratory, descriptive and contextual in nature. The exploratory-descriptive design allowed the researcher to understand the topic by using a narrative strategy of inquiry. A non-probability purposive sampling method was applied to identify five older persons as well as the adult children of these older persons who are retirees of an automotive company in South Africa. Individual, semi-structured face to face interviews were conducted with older persons as well as with at least one of their adult children who did not reside with them. Thematic data analysis technique was used to analyse the data collected. The study is viewed as significant in enhancing the understanding of satisfying and caring relationships between older persons and their adult children in order to add to the body of existing knowledge in social gerontology and to improve direct social work practice with older persons.
- Full Text:
- Date Issued: 2016
Lives "on hold": the Daily Sun and the South African identity document
- Authors: Boshoff, Priscilla A
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143538 , vital:38255 , https://hdl.handle.net/10520/EJC195358
- Description: The relationship between a personal identity and the state-issued Identity Document (ID) is the focus of this article, which examines stories published in the "Horror Affairs" column of the popular South African tabloid, the Daily Sun. These highly emotional stories tell of the despair and desperation felt by individuals at the lack of an ID book, which is blamed on the inefficiency of the state Department of Home Affairs. In order to explicate this relationship I make use of Agamben's notion of "bare life" and the camp in conjunction with Lacan's idea of the Symbolic Order to argue that if the Identity Document provides the means by which the individual is made to signify, the lack of an Identity Document threatens to reduce the individual to "bare life". By publishing the stories of those deprived of the visibility that the ID provides, the Daily Sun, I show, directly engages in this exchange, and, in contrast to Home Affairs, bestows its own even stronger gift of identity by the fact of appearance in its pages.
- Full Text:
- Date Issued: 2016
- Authors: Boshoff, Priscilla A
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/143538 , vital:38255 , https://hdl.handle.net/10520/EJC195358
- Description: The relationship between a personal identity and the state-issued Identity Document (ID) is the focus of this article, which examines stories published in the "Horror Affairs" column of the popular South African tabloid, the Daily Sun. These highly emotional stories tell of the despair and desperation felt by individuals at the lack of an ID book, which is blamed on the inefficiency of the state Department of Home Affairs. In order to explicate this relationship I make use of Agamben's notion of "bare life" and the camp in conjunction with Lacan's idea of the Symbolic Order to argue that if the Identity Document provides the means by which the individual is made to signify, the lack of an Identity Document threatens to reduce the individual to "bare life". By publishing the stories of those deprived of the visibility that the ID provides, the Daily Sun, I show, directly engages in this exchange, and, in contrast to Home Affairs, bestows its own even stronger gift of identity by the fact of appearance in its pages.
- Full Text:
- Date Issued: 2016
A model for Internet management at a higher education institution
- Authors: Boshoff, Ryno
- Date: 2016
- Subjects: Internet governance -- South Africa -- Port Elizabeth Internet -- Security measures -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/10839 , vital:26828
- Description: The management of the Internet at the Nelson Mandela Metropolitan University (NMMU), an Higher Education Institute (HEI) in the Eastern and Western Cape area in South Africa (SA) was the focus of this research. The investigation was conducted into the level of Internet usage by determining for what purpose the Internet is used by the people at NMMU. The empirical data was collected, analysed and interpreted. From these findings a proposed Internet Management Model was created that will assist NMMU with its Internet management obligations. It has become a standing practice at HEIs for its Internet management and relevant Information and Communication Technology (ICT) resources to be continuously investigated by HEI Management as well as by its users. The reason is that the Internet has become the foundation on which most ICT resources function and therefore is labelled as a distinctive competency for the HEI. HEIs have limited ICT Internet resources and are expected to utilise these resources optimally, to ensure efficient and effective Internet connectivity on all campuses and to all users and systems. This is a daunting task for various reasons, amongst which are: guidelines, best practices, governance influences, etc. are not readily available to assist with decision-making processes; the number of devices that require Internet connectivity is increasing almost on a daily basis; the content found on the Internet has become extremely resources-demanding; the Internet is no longer being utilised only during working hours but on a 24/7 basis; and lastly, the Internet is increasingly being abused by its use for non-work related activities which hinder the required connection and resources requirements for those who are using the Internet for work and research purposes. The purpose of this research study was to provide a proposed Internet Management Model to address all weaknesses and threats, currently being experienced at NMMU. This was created by firstly; determining what was considered best practices regarding Internet management at HEI; secondly, determining what the NMMU Internet users were utilising the Internet for and lastly; using the combined findings to draw conclusions and thereafter create an Internet Management Model for the HEI. This can assist the NMMU ICT Management team to re-align the Internet resources to match the current business and customer requirements. This will ensure that the NMMU Internet resources are effectively and efficiently utilised, which in turn will confirm that the availability of the Internet to its users and systems becomes a reliable and pleasant experience. The ICT Management team can then focus their undivided attention on other ICT-related matters. This treatise is an exploratory, mixed method study which comprises of literature studies, surveys and cross-sectional studies. The literature studies were conducted on secondary sources to identify the national and international governance structures that influence Internet management. The empirical study which consisted of two surveys (questionnaires) was compiled from existing questionnaires as well as from literature studies, and was completed by its respective respondent groups. The first survey was used to gain an insight into what was considered best practices regarding Internet management at HEIs in South Africa. The survey consisted of questions regarding demographic data and various ICT Internet resources. Respondents were asked to identify the practices relevant to their HEI. The second survey was used to gain an insight into what the Internet was being used for at NMMU by staff and students. The survey consisted of questions regarding demographic data and the various uses, frequency and periods of Internet usage. These respondents were then asked to identify the practices relevant to their Internet usage patterns. A cross-sectional study was then used to compare the two different population groups, which were NMMU staff and students, at a single point in time. Both Descriptive and Inferential Statistical methods were used for the analysis of the data. The HEI Internet management survey samples were of various sizes with each sample having its Internet resources specifically aligned with its environment. The common stereotypes regarding their Internet resources were mostly not present.
- Full Text:
- Date Issued: 2016
- Authors: Boshoff, Ryno
- Date: 2016
- Subjects: Internet governance -- South Africa -- Port Elizabeth Internet -- Security measures -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/10839 , vital:26828
- Description: The management of the Internet at the Nelson Mandela Metropolitan University (NMMU), an Higher Education Institute (HEI) in the Eastern and Western Cape area in South Africa (SA) was the focus of this research. The investigation was conducted into the level of Internet usage by determining for what purpose the Internet is used by the people at NMMU. The empirical data was collected, analysed and interpreted. From these findings a proposed Internet Management Model was created that will assist NMMU with its Internet management obligations. It has become a standing practice at HEIs for its Internet management and relevant Information and Communication Technology (ICT) resources to be continuously investigated by HEI Management as well as by its users. The reason is that the Internet has become the foundation on which most ICT resources function and therefore is labelled as a distinctive competency for the HEI. HEIs have limited ICT Internet resources and are expected to utilise these resources optimally, to ensure efficient and effective Internet connectivity on all campuses and to all users and systems. This is a daunting task for various reasons, amongst which are: guidelines, best practices, governance influences, etc. are not readily available to assist with decision-making processes; the number of devices that require Internet connectivity is increasing almost on a daily basis; the content found on the Internet has become extremely resources-demanding; the Internet is no longer being utilised only during working hours but on a 24/7 basis; and lastly, the Internet is increasingly being abused by its use for non-work related activities which hinder the required connection and resources requirements for those who are using the Internet for work and research purposes. The purpose of this research study was to provide a proposed Internet Management Model to address all weaknesses and threats, currently being experienced at NMMU. This was created by firstly; determining what was considered best practices regarding Internet management at HEI; secondly, determining what the NMMU Internet users were utilising the Internet for and lastly; using the combined findings to draw conclusions and thereafter create an Internet Management Model for the HEI. This can assist the NMMU ICT Management team to re-align the Internet resources to match the current business and customer requirements. This will ensure that the NMMU Internet resources are effectively and efficiently utilised, which in turn will confirm that the availability of the Internet to its users and systems becomes a reliable and pleasant experience. The ICT Management team can then focus their undivided attention on other ICT-related matters. This treatise is an exploratory, mixed method study which comprises of literature studies, surveys and cross-sectional studies. The literature studies were conducted on secondary sources to identify the national and international governance structures that influence Internet management. The empirical study which consisted of two surveys (questionnaires) was compiled from existing questionnaires as well as from literature studies, and was completed by its respective respondent groups. The first survey was used to gain an insight into what was considered best practices regarding Internet management at HEIs in South Africa. The survey consisted of questions regarding demographic data and various ICT Internet resources. Respondents were asked to identify the practices relevant to their HEI. The second survey was used to gain an insight into what the Internet was being used for at NMMU by staff and students. The survey consisted of questions regarding demographic data and the various uses, frequency and periods of Internet usage. These respondents were then asked to identify the practices relevant to their Internet usage patterns. A cross-sectional study was then used to compare the two different population groups, which were NMMU staff and students, at a single point in time. Both Descriptive and Inferential Statistical methods were used for the analysis of the data. The HEI Internet management survey samples were of various sizes with each sample having its Internet resources specifically aligned with its environment. The common stereotypes regarding their Internet resources were mostly not present.
- Full Text:
- Date Issued: 2016
The management of chacma baboons and humans in a peri-urban environment: a case study from Nelson Mandela Metropolitan University's George Campus
- Authors: Botes, Peet
- Date: 2016
- Subjects: Human-animal relationships , Animal behavior , Human beings , Bestiality
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/5135 , vital:20812
- Description: Conflicts between humans and baboons (Papio ursinus) have become a significant management challenge on Nelson Mandela Metropolitan University’s (NMMUs) George Campus, which is located in peri-urban George in the Garden Route, of the Western Cape of South Africa. Current management policy, although required to be ‘scientifically’ based, largely relies on studies done outside the Garden Route. This study addresses the question of how the management of human-baboon relations could be improved on the campus. A case study was undertaken which aimed at addressing the cohabitation of baboons and humans on the NMMU campus, specifically human-baboon resource selection and interaction. The research methodology and the related analytical tools were primarily quantitative but were supplemented by some qualitative data drawn from interviews. Data collected was used to determine landscape features acting as Keystone Resource Areas (KRAs) for both humans and baboons on the campus. Relationships between the frequency and location of negative interactions, and resident-baboon distribution on the campus were also determined. Two key findings emerged from the research. First, residences, non-residence buildings and waste disposal stations act as KRAs for both humans and baboons. Second, the frequency of negative interaction correlates with the time spent by residents and baboons at residences, where common negative interactions between baboons and humans are known to occur. It is postulated that cohabitation on the NMMU George Campus is causing the habituation of baboons, a loss of fear of humans and association of humans with high energy foods. As a result, present cohabitation contributes to negative human-baboon relations in the George area. To ensure sustainable co-existence between humans and baboons on the George Campus, management should implement zonation and wildlife monitoring to reverse the loss of baboon fear of humans and better limit the availability of human-derived foods. In addition, management should consider giving stakeholders co-management roles to foster and facilitate knowledge and responsibility partnerships, and subsequently correct any misunderstandings related to human-baboon relations on the campus. Recommendations for further research include sampling beyond campus boundaries to compensate for regional variations in baboon behaviour and the biophysical environment.
- Full Text:
- Date Issued: 2016
- Authors: Botes, Peet
- Date: 2016
- Subjects: Human-animal relationships , Animal behavior , Human beings , Bestiality
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/5135 , vital:20812
- Description: Conflicts between humans and baboons (Papio ursinus) have become a significant management challenge on Nelson Mandela Metropolitan University’s (NMMUs) George Campus, which is located in peri-urban George in the Garden Route, of the Western Cape of South Africa. Current management policy, although required to be ‘scientifically’ based, largely relies on studies done outside the Garden Route. This study addresses the question of how the management of human-baboon relations could be improved on the campus. A case study was undertaken which aimed at addressing the cohabitation of baboons and humans on the NMMU campus, specifically human-baboon resource selection and interaction. The research methodology and the related analytical tools were primarily quantitative but were supplemented by some qualitative data drawn from interviews. Data collected was used to determine landscape features acting as Keystone Resource Areas (KRAs) for both humans and baboons on the campus. Relationships between the frequency and location of negative interactions, and resident-baboon distribution on the campus were also determined. Two key findings emerged from the research. First, residences, non-residence buildings and waste disposal stations act as KRAs for both humans and baboons. Second, the frequency of negative interaction correlates with the time spent by residents and baboons at residences, where common negative interactions between baboons and humans are known to occur. It is postulated that cohabitation on the NMMU George Campus is causing the habituation of baboons, a loss of fear of humans and association of humans with high energy foods. As a result, present cohabitation contributes to negative human-baboon relations in the George area. To ensure sustainable co-existence between humans and baboons on the George Campus, management should implement zonation and wildlife monitoring to reverse the loss of baboon fear of humans and better limit the availability of human-derived foods. In addition, management should consider giving stakeholders co-management roles to foster and facilitate knowledge and responsibility partnerships, and subsequently correct any misunderstandings related to human-baboon relations on the campus. Recommendations for further research include sampling beyond campus boundaries to compensate for regional variations in baboon behaviour and the biophysical environment.
- Full Text:
- Date Issued: 2016
Russian wheat aphids: Breakfast, lunch, and supper. Feasting on small grains in South Africa
- Botha, Christiaan E J, Sacranie, S, Gallagher, Sean, Hill, Jaclyn M
- Authors: Botha, Christiaan E J , Sacranie, S , Gallagher, Sean , Hill, Jaclyn M
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69031 , vital:29374 , https://doi.org/10.1016/j.sajb.2016.12.006
- Description: The Russian Wheat Aphid (Diuraphis noxia, RWA) negatively impacts commercially grown barley and wheat in South Africa. Climate change, the attendant rise in [CO2], and the appearance of new RWA biotypes have the potential to induce severe crop yield loss in agriculturally important wheat and barley cultivars. This study presents data showing changes in relative aphid population numbers, concurrently with assessments of plant damage under controlled environmental conditions, under ambient and elevated (450 ppm) [CO2]. Extensive structural damage to the vascular tissue and disruption to the transport systems were revealed using light, fluorescence and electron microscopy. This, coupled with biotype population studies, demonstrated that RWA has the capacity to inflict severe, potentially permanent damage to vegetative small grain plants. Furthermore, some currently ‘resistant’ cultivars may well lose resistance as a direct result of increasing atmospheric [CO2]. A small (50 ppm) increase in atmospheric [CO2] may result in increased aphid population numbers, potentially serious plant damage and, by implication, a potentially negative impact on yield, as increased aphid density per plant leads to an accelerated disruption of the assimilate and transpiration transport pathways. These outcomes pose a direct threat to the commercial small grain industry of South Africa and by extension, to other small grain production areas elsewhere.
- Full Text: false
- Date Issued: 2016
- Authors: Botha, Christiaan E J , Sacranie, S , Gallagher, Sean , Hill, Jaclyn M
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/69031 , vital:29374 , https://doi.org/10.1016/j.sajb.2016.12.006
- Description: The Russian Wheat Aphid (Diuraphis noxia, RWA) negatively impacts commercially grown barley and wheat in South Africa. Climate change, the attendant rise in [CO2], and the appearance of new RWA biotypes have the potential to induce severe crop yield loss in agriculturally important wheat and barley cultivars. This study presents data showing changes in relative aphid population numbers, concurrently with assessments of plant damage under controlled environmental conditions, under ambient and elevated (450 ppm) [CO2]. Extensive structural damage to the vascular tissue and disruption to the transport systems were revealed using light, fluorescence and electron microscopy. This, coupled with biotype population studies, demonstrated that RWA has the capacity to inflict severe, potentially permanent damage to vegetative small grain plants. Furthermore, some currently ‘resistant’ cultivars may well lose resistance as a direct result of increasing atmospheric [CO2]. A small (50 ppm) increase in atmospheric [CO2] may result in increased aphid population numbers, potentially serious plant damage and, by implication, a potentially negative impact on yield, as increased aphid density per plant leads to an accelerated disruption of the assimilate and transpiration transport pathways. These outcomes pose a direct threat to the commercial small grain industry of South Africa and by extension, to other small grain production areas elsewhere.
- Full Text: false
- Date Issued: 2016
Art investment in South Africa: portfolio diversification and art market efficiency
- Botha, Ferdi, Snowball, Jeanette D, Scott, Brett
- Authors: Botha, Ferdi , Snowball, Jeanette D , Scott, Brett
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/64794 , vital:28601 , http://www.dx.doi.org/10.17159/2222-3436/2016/v19n3a4
- Description: Art has been suggested as a good way to diversify investment portfolios during times of financial uncertainty. The argument is that art exhibits different risk and return characteristics to conventional investments in other asset classes. The new Citadel art price index offered the opportunity to test this theory in the South African context. Moreover, this paper tests whether art prices are efficient. The Citadel index uses the hedonic regression method with observations drawn from the top 100, 50 and 20 artists by sales volume, giving approximately 29 503 total auction observations. The Index consists of quarterly data from the period 2000Q1 to 2013Q3. A vector autoregression of the art price index, Johannesburg stock exchange all-share index, house price index, and South African government bond index were used. Results show that, when there are increased returns on the stock market in a preceding period and wealth increases, there is a change in the Citadel art price index in the same direction. No significant difference was found between the house price index and the art price index, or between the art and government bond price indices. The art market is also found to be inefficient, thereby exacerbating the risk of investing in art. Overall, the South African art market does not offer the opportunity to diversify portfolios dominated by either property, bonds, or shares.
- Full Text:
- Date Issued: 2016
- Authors: Botha, Ferdi , Snowball, Jeanette D , Scott, Brett
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/64794 , vital:28601 , http://www.dx.doi.org/10.17159/2222-3436/2016/v19n3a4
- Description: Art has been suggested as a good way to diversify investment portfolios during times of financial uncertainty. The argument is that art exhibits different risk and return characteristics to conventional investments in other asset classes. The new Citadel art price index offered the opportunity to test this theory in the South African context. Moreover, this paper tests whether art prices are efficient. The Citadel index uses the hedonic regression method with observations drawn from the top 100, 50 and 20 artists by sales volume, giving approximately 29 503 total auction observations. The Index consists of quarterly data from the period 2000Q1 to 2013Q3. A vector autoregression of the art price index, Johannesburg stock exchange all-share index, house price index, and South African government bond index were used. Results show that, when there are increased returns on the stock market in a preceding period and wealth increases, there is a change in the Citadel art price index in the same direction. No significant difference was found between the house price index and the art price index, or between the art and government bond price indices. The art market is also found to be inefficient, thereby exacerbating the risk of investing in art. Overall, the South African art market does not offer the opportunity to diversify portfolios dominated by either property, bonds, or shares.
- Full Text:
- Date Issued: 2016
The good African society index
- Authors: Botha, Ferdi
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/396194 , vital:69157 , xlink:href="https://doi.org/10.1007/s11205-015-0891-z"
- Description: This paper constructs a Good Society Index for 45 African countries, termed the Good African Society Index (GASI). The GASI consists of nine main indexes: (1) economic sustainability, (2) democracy and freedom, (3) child well-being, (4) environment and infrastructure, (5) safety and security, (6) health and health systems, (7) integrity and justice, (8) education, and (9) social sustainability and social cohesion. Each component is split into four sub-components for a total of 36 indicators. Tunisia ranks highest on the GASI, followed by Cape Verde and Botswana. Chad has the lowest GASI score, followed by Central African Republic and Cote d’Ivoire. The GASI is strongly related to the 2012 Human Development Index and Fragile States Index, to a lesser extent, GNI per capita.
- Full Text:
- Date Issued: 2016
- Authors: Botha, Ferdi
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/396194 , vital:69157 , xlink:href="https://doi.org/10.1007/s11205-015-0891-z"
- Description: This paper constructs a Good Society Index for 45 African countries, termed the Good African Society Index (GASI). The GASI consists of nine main indexes: (1) economic sustainability, (2) democracy and freedom, (3) child well-being, (4) environment and infrastructure, (5) safety and security, (6) health and health systems, (7) integrity and justice, (8) education, and (9) social sustainability and social cohesion. Each component is split into four sub-components for a total of 36 indicators. Tunisia ranks highest on the GASI, followed by Cape Verde and Botswana. Chad has the lowest GASI score, followed by Central African Republic and Cote d’Ivoire. The GASI is strongly related to the 2012 Human Development Index and Fragile States Index, to a lesser extent, GNI per capita.
- Full Text:
- Date Issued: 2016
Hate speech as a limitation to freedom of expression
- Authors: Botha, Joanna Catherine
- Date: 2016
- Subjects: Freedom of speech -- South Africa , Hate speech -- South Africa , Civil rights -- South Africa
- Language: English
- Type: Thesis , Doctoral , LLD
- Identifier: http://hdl.handle.net/10948/9054 , vital:26460
- Description: Hate speech in South Africa creates a tension between the right to freedom of expression and the rights to human dignity and equality. The challenge is to achieve a balance between these competing rights in the context of the divisive past and the transformative constitutional ideal, in which reconciliation and respect for group difference are promoted. Freedom of expression, an individual right, must be construed in light of its underlying values, but regard must also be given to communitarian interests. The constitutional standard draws the initial line. The advocacy of hatred on four grounds and which constitutes incitement to cause harm is not constitutionally protected speech. Such speech undermines nation building, causes acrimony, and is not tolerated in the egalitarian society envisaged by the Constitution. The thesis formulates a principled legislative hate speech framework for South Africa at both human rights and criminal levels within the parameters of the constitutional mandate, as guided by the standard for hate speech restrictions in international law, and the Canadian regulatory model. An essential premise is that regulation requires a multi-faceted balancing enquiry. A holistic approach is proposed where factors such as respect for the dignity of the victims, autonomy for speakers, listeners and the wider community; the causal link between hate speech and hatred in a community; and the desire to achieve a diverse and harmonious society; amongst others, are considered. Failure to regulate hate speech constructively endorses hatemongers and promotes damaging speech at the expense of vulnerable groups. Regulation ensures that law sets the normative benchmark, affirms the protection of vulnerable groups within the social fabric and upholds social cohesion, inclusiveness and the equal citizenship of all individuals in society. The thesis contains a proposal for the enactment of legislation creating a self-standing hate speech crime for the advocacy of extreme hatred, shaped in accordance with international requirements and comparative foreign law, and structured in light of the distinction between hate crime and hate speech. The existing legal framework is unable to provide consistent and fitting redress for the severe harm caused by such speech, namely the fostering of an environment in which the stigmatisation of groups is promoted, their exclusion from society justified and intervention is needed to remedy the escalated levels of hatred and violence between different groups in society. PEPUDA, a remedial statute aimed at promoting transformation and substantive equality, is valuable, but its speech prohibitions are broad and imprecise. Consequently, their effectiveness is compromised and their constitutionality questioned. The thesis proposes recommendations for amendments to sections 7(a), 10(1) and 12 of PEPUDA. The aim is to ensure compliance with the international standard and to foster the optimal regulation of hate speech and other forms of damaging speech, including derogatory racial epithets, which undermine human dignity and equality and threaten national unity. It is intended for the two systems to complement one another and to create a legal framework aimed at addressing hate speech constructively and in context, promoting tolerance, respect for difference, reconciliation and transformation.
- Full Text:
- Date Issued: 2016
- Authors: Botha, Joanna Catherine
- Date: 2016
- Subjects: Freedom of speech -- South Africa , Hate speech -- South Africa , Civil rights -- South Africa
- Language: English
- Type: Thesis , Doctoral , LLD
- Identifier: http://hdl.handle.net/10948/9054 , vital:26460
- Description: Hate speech in South Africa creates a tension between the right to freedom of expression and the rights to human dignity and equality. The challenge is to achieve a balance between these competing rights in the context of the divisive past and the transformative constitutional ideal, in which reconciliation and respect for group difference are promoted. Freedom of expression, an individual right, must be construed in light of its underlying values, but regard must also be given to communitarian interests. The constitutional standard draws the initial line. The advocacy of hatred on four grounds and which constitutes incitement to cause harm is not constitutionally protected speech. Such speech undermines nation building, causes acrimony, and is not tolerated in the egalitarian society envisaged by the Constitution. The thesis formulates a principled legislative hate speech framework for South Africa at both human rights and criminal levels within the parameters of the constitutional mandate, as guided by the standard for hate speech restrictions in international law, and the Canadian regulatory model. An essential premise is that regulation requires a multi-faceted balancing enquiry. A holistic approach is proposed where factors such as respect for the dignity of the victims, autonomy for speakers, listeners and the wider community; the causal link between hate speech and hatred in a community; and the desire to achieve a diverse and harmonious society; amongst others, are considered. Failure to regulate hate speech constructively endorses hatemongers and promotes damaging speech at the expense of vulnerable groups. Regulation ensures that law sets the normative benchmark, affirms the protection of vulnerable groups within the social fabric and upholds social cohesion, inclusiveness and the equal citizenship of all individuals in society. The thesis contains a proposal for the enactment of legislation creating a self-standing hate speech crime for the advocacy of extreme hatred, shaped in accordance with international requirements and comparative foreign law, and structured in light of the distinction between hate crime and hate speech. The existing legal framework is unable to provide consistent and fitting redress for the severe harm caused by such speech, namely the fostering of an environment in which the stigmatisation of groups is promoted, their exclusion from society justified and intervention is needed to remedy the escalated levels of hatred and violence between different groups in society. PEPUDA, a remedial statute aimed at promoting transformation and substantive equality, is valuable, but its speech prohibitions are broad and imprecise. Consequently, their effectiveness is compromised and their constitutionality questioned. The thesis proposes recommendations for amendments to sections 7(a), 10(1) and 12 of PEPUDA. The aim is to ensure compliance with the international standard and to foster the optimal regulation of hate speech and other forms of damaging speech, including derogatory racial epithets, which undermine human dignity and equality and threaten national unity. It is intended for the two systems to complement one another and to create a legal framework aimed at addressing hate speech constructively and in context, promoting tolerance, respect for difference, reconciliation and transformation.
- Full Text:
- Date Issued: 2016
The effective management of customer orders received by a pharmaceutical manufacturer
- Authors: Botha, Risca
- Date: 2016
- Subjects: Pharmaceutical industry -- Customer services , Business logistics , Physical distribution of goods -- Management
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/9087 , vital:26463
- Description: There is a great need for a pharmaceutical manufacturer to provide its customers with the right product at the right time, place and price and also to deliver the product in the right quantity and quality. Should pharmaceutical customers not receive their orders on time from the pharmaceutical manufacturer, the customers might face out-of-stock situations. As a result, the patients or customers might turn to an alternative product from a different pharmaceutical manufacturer, which has the required stock readily available. This could lead to loss in sales and even death amongst its customers. The main objective of this study was to determine the key factors that form part of the demand and operations planning strategies to ensure that these factors are in place to effectively manage and execute the supply chain and logistics processes to reduce possible out-of-stock situations amongst its customers. As a starting point to the study, an analysis was performed based on the review of relevant research and literature from various text books, journals, publications, as well as internet sources. The literature study covered various aspects such as demand planning, production planning, the use of different demand and operations planning strategies, as well as the importance of continuous internal and external customer service levels to ensure that customer orders are delivered on time. The analysis of the literature review was used to establish a theoretical basis for the design and structure of the questionnaire that was used as a research instrument in this study. A survey was conducted amongst the employees that are responsible for executing the supply chain and logistics processes within Aspen Pharmacare. These employees resided within the three main departments of the pharmaceutical manufacturer, namely, the Demand and Operations Planning, Production and Packing, as well as the Warehouse and Distribution departments. Each question posed in the questionnaire related to the role of each employee within these departments that are responsible for the logistics processes within Aspen Pharmacare. The empirical results from the study indicated that the respondents were in support that specific key factors are important for a pharmaceutical manufacturer to manage incoming customer orders efficiently and effectively to reduce possible out-of-stock situations amongst its end customers. However, the respondents also highlighted that there were a number of obstacles preventing them from implementing the key factors that are required to manage incoming customer orders more efficiently within the pharmaceutical manufacturer. Some of these obstacles include: the lack of pro- activeness; lack of accountability; and the lack of constant communication between the employees from the three main departments. Furthermore, incomplete hand-over information during shift changes amongst the employees of the Production and Packing department created unnecessary down-time. Also, the employees from the Warehouse and Distribution department were not informed timeously when changes to the production schedule were made. These obstacles will have a negative impact on the ultimate customer delivery dates and need to be addressed. The empirical results highlighted some recommendations to assist pharmaceutical manufacturing companies to more effectively and efficiently manage their incoming customer orders to reduce or eliminate any possible out-of-stock situations amongst its end customers. Some recommendations include: improved communication between the three main departments; to react immediately to out-of-stock products; and to ensure that internal and external customer service levels are adhered to at all times. The implementation of the recommendations based on the empirical findings of the study will assist the pharmaceutical manufacturing company to achieve excellence and to become a world-class supplier of generic pharmaceutical products. In this way, all incoming customer orders can be fulfilled on time.
- Full Text:
- Date Issued: 2016
- Authors: Botha, Risca
- Date: 2016
- Subjects: Pharmaceutical industry -- Customer services , Business logistics , Physical distribution of goods -- Management
- Language: English
- Type: Thesis , Masters , MTech
- Identifier: http://hdl.handle.net/10948/9087 , vital:26463
- Description: There is a great need for a pharmaceutical manufacturer to provide its customers with the right product at the right time, place and price and also to deliver the product in the right quantity and quality. Should pharmaceutical customers not receive their orders on time from the pharmaceutical manufacturer, the customers might face out-of-stock situations. As a result, the patients or customers might turn to an alternative product from a different pharmaceutical manufacturer, which has the required stock readily available. This could lead to loss in sales and even death amongst its customers. The main objective of this study was to determine the key factors that form part of the demand and operations planning strategies to ensure that these factors are in place to effectively manage and execute the supply chain and logistics processes to reduce possible out-of-stock situations amongst its customers. As a starting point to the study, an analysis was performed based on the review of relevant research and literature from various text books, journals, publications, as well as internet sources. The literature study covered various aspects such as demand planning, production planning, the use of different demand and operations planning strategies, as well as the importance of continuous internal and external customer service levels to ensure that customer orders are delivered on time. The analysis of the literature review was used to establish a theoretical basis for the design and structure of the questionnaire that was used as a research instrument in this study. A survey was conducted amongst the employees that are responsible for executing the supply chain and logistics processes within Aspen Pharmacare. These employees resided within the three main departments of the pharmaceutical manufacturer, namely, the Demand and Operations Planning, Production and Packing, as well as the Warehouse and Distribution departments. Each question posed in the questionnaire related to the role of each employee within these departments that are responsible for the logistics processes within Aspen Pharmacare. The empirical results from the study indicated that the respondents were in support that specific key factors are important for a pharmaceutical manufacturer to manage incoming customer orders efficiently and effectively to reduce possible out-of-stock situations amongst its end customers. However, the respondents also highlighted that there were a number of obstacles preventing them from implementing the key factors that are required to manage incoming customer orders more efficiently within the pharmaceutical manufacturer. Some of these obstacles include: the lack of pro- activeness; lack of accountability; and the lack of constant communication between the employees from the three main departments. Furthermore, incomplete hand-over information during shift changes amongst the employees of the Production and Packing department created unnecessary down-time. Also, the employees from the Warehouse and Distribution department were not informed timeously when changes to the production schedule were made. These obstacles will have a negative impact on the ultimate customer delivery dates and need to be addressed. The empirical results highlighted some recommendations to assist pharmaceutical manufacturing companies to more effectively and efficiently manage their incoming customer orders to reduce or eliminate any possible out-of-stock situations amongst its end customers. Some recommendations include: improved communication between the three main departments; to react immediately to out-of-stock products; and to ensure that internal and external customer service levels are adhered to at all times. The implementation of the recommendations based on the empirical findings of the study will assist the pharmaceutical manufacturing company to achieve excellence and to become a world-class supplier of generic pharmaceutical products. In this way, all incoming customer orders can be fulfilled on time.
- Full Text:
- Date Issued: 2016
The design of an international wool exchange for Port Elizabeth
- Authors: Bothma, Ashley Andre
- Date: 2016
- Subjects: Historic sites -- South Africa -- Port Elizabeth Historic buildings -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/38852 , vital:35007
- Description: Due to the growth increase in the wool industry in South Africa and the industry's lack of public activity that the existing South Africa (S.A) wool exchange exudes, the opportunity for a new type of wool exchange presents itself. the advantages in technology have evolved in many an industry and the same can be for the wool industry. the existing S.A. wool exchange fails to comfortably meet the needs of the industry with regards to technology. the creation of international wool exchange will provide a platform to boost the industry and incorporate the use of current technology to improve on the process involved within the program. BKB. Ltd have expressed a similar interest in the development of an international wool exchange but have requested the use of an abounded heritage building in an attempt at a sustainable future through re-use.
- Full Text:
- Date Issued: 2016
- Authors: Bothma, Ashley Andre
- Date: 2016
- Subjects: Historic sites -- South Africa -- Port Elizabeth Historic buildings -- South Africa -- Port Elizabeth
- Language: English
- Type: Thesis , Masters , MArch
- Identifier: http://hdl.handle.net/10948/38852 , vital:35007
- Description: Due to the growth increase in the wool industry in South Africa and the industry's lack of public activity that the existing South Africa (S.A) wool exchange exudes, the opportunity for a new type of wool exchange presents itself. the advantages in technology have evolved in many an industry and the same can be for the wool industry. the existing S.A. wool exchange fails to comfortably meet the needs of the industry with regards to technology. the creation of international wool exchange will provide a platform to boost the industry and incorporate the use of current technology to improve on the process involved within the program. BKB. Ltd have expressed a similar interest in the development of an international wool exchange but have requested the use of an abounded heritage building in an attempt at a sustainable future through re-use.
- Full Text:
- Date Issued: 2016
Cultural events hosted in Nelson Mandela Bay
- Boucher, Sasha Marilyn, Calitz, André
- Authors: Boucher, Sasha Marilyn , Calitz, André
- Date: 2016
- Subjects: Heritage tourism Special events -- Management
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/11823 , vital:26976
- Description: Purpose – This study seeks to explore residents’ attitudes towards cultural events in Nelson Mandela Bay (NMB), South Africa. The study further discusses the cultural values and social realities of the diverse socio-economic landscape inherent to the city. Equally, the extent of stakeholder involvement has been reflected throughout the study as an indispensable requirement towards sustainable tourism in the city. The study presents that customising cultural events according to the cross-cultural typology has far-reaching consequences in enhancing the image of NMB and induces stakeholder engagement. This study is based on the notion of Social Capital and Stakeholder theory and draws on the multi-cultural phenomenon as the thrust of the study is based on attracting residents’ to cultural events. The literature study indicated that the concept of Social Capital and stakeholder collaboration are mutually exclusive and empirical analysis indicates a strong relationship between the factors relative to residents’ attitudes. Design/Methodology/Approach – This study is located in the positivism paradigm and comprises literature and exploratory research to examine the supposition between the independent variables and the attitudes of residents’ in the NMB. The independent variables underlined in the proposed model are embedded in the literature undertaken. Equally, the thrust of the study is underpinned in Social Capital theory and the Stakeholder theory and is evident throughout this study. In this study, the convenience sampling and snowball sampling methods were employed to obtain a representative sample of residents from the NMB. A questionnaire was used in this study to solicit responses pertaining to the biographical information and questions relating to the factors of perceived satisfaction of residents in the NMB in relation to cultural events. A total number of 3,659 residents participated in this study. The researcher conducted this study by means of testing the constructs of the measuring instrument employed, as well as providing a causal model of relationships between the independent variables and the residents’ attitudes of cultural events in NMB. Findings – The results confirm the reliability and validity of the scales tested on a sample of 3,659 residents, collected using the questionnaire in Nelson Mandela Bay Metropolitan area. The empirical analysis indicates relationships among the independent factors; Social Capital and Stakeholder Profile, where a Pearson’s correlation of 0.50 exists. Furthermore, descriptive findings indicate that there is an overall positive tendency in attitudes for cultural events in the city. The practical significance as identified in the Cohen’s d test for significance infers that the moderating factors in the conceptual model prove that age, area code, home language, ethnicity and home language exert influence in determining residents’ attitudes in the city. Practical Implications – This study identifies the importance of leveraging the cross-cultural typology underscored the Stakeholder theory. Equally, for destination marketing organisations (DMOs) this study can glean insights in respect of the profile of residents for cultural event marketing and their response as stakeholders in the organisation of a cultural event. Social Implications – This study aims to gain a better understanding of the residents’ attitudes of the cultural events hosted by the NMB, its Social Capital and its relationship with varying demographic niches and cultural-centric insights that align to the ideologies pertaining to global citizenship. Originality/Value – This present study makes a contribution to the theories of Social Capital and Stakeholder theory by investigating its roles in determining residents’ attitudes of cultural events in a city. Moreover, it discusses the role of the factors as inducing variables for residents’ motivation by employing marketing principles related to the unique and emotional selling proposition philosophy. Equally, the study espouses the significance of promoting cultural events to extent that it acts as a platform to promote socio-economic development; employment opportunities, improved living standards, improving city infrastructure and environmental protection of a destination and justifies the expedition of Social Capital on the attitudes of residents’.
- Full Text:
- Date Issued: 2016
- Authors: Boucher, Sasha Marilyn , Calitz, André
- Date: 2016
- Subjects: Heritage tourism Special events -- Management
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10948/11823 , vital:26976
- Description: Purpose – This study seeks to explore residents’ attitudes towards cultural events in Nelson Mandela Bay (NMB), South Africa. The study further discusses the cultural values and social realities of the diverse socio-economic landscape inherent to the city. Equally, the extent of stakeholder involvement has been reflected throughout the study as an indispensable requirement towards sustainable tourism in the city. The study presents that customising cultural events according to the cross-cultural typology has far-reaching consequences in enhancing the image of NMB and induces stakeholder engagement. This study is based on the notion of Social Capital and Stakeholder theory and draws on the multi-cultural phenomenon as the thrust of the study is based on attracting residents’ to cultural events. The literature study indicated that the concept of Social Capital and stakeholder collaboration are mutually exclusive and empirical analysis indicates a strong relationship between the factors relative to residents’ attitudes. Design/Methodology/Approach – This study is located in the positivism paradigm and comprises literature and exploratory research to examine the supposition between the independent variables and the attitudes of residents’ in the NMB. The independent variables underlined in the proposed model are embedded in the literature undertaken. Equally, the thrust of the study is underpinned in Social Capital theory and the Stakeholder theory and is evident throughout this study. In this study, the convenience sampling and snowball sampling methods were employed to obtain a representative sample of residents from the NMB. A questionnaire was used in this study to solicit responses pertaining to the biographical information and questions relating to the factors of perceived satisfaction of residents in the NMB in relation to cultural events. A total number of 3,659 residents participated in this study. The researcher conducted this study by means of testing the constructs of the measuring instrument employed, as well as providing a causal model of relationships between the independent variables and the residents’ attitudes of cultural events in NMB. Findings – The results confirm the reliability and validity of the scales tested on a sample of 3,659 residents, collected using the questionnaire in Nelson Mandela Bay Metropolitan area. The empirical analysis indicates relationships among the independent factors; Social Capital and Stakeholder Profile, where a Pearson’s correlation of 0.50 exists. Furthermore, descriptive findings indicate that there is an overall positive tendency in attitudes for cultural events in the city. The practical significance as identified in the Cohen’s d test for significance infers that the moderating factors in the conceptual model prove that age, area code, home language, ethnicity and home language exert influence in determining residents’ attitudes in the city. Practical Implications – This study identifies the importance of leveraging the cross-cultural typology underscored the Stakeholder theory. Equally, for destination marketing organisations (DMOs) this study can glean insights in respect of the profile of residents for cultural event marketing and their response as stakeholders in the organisation of a cultural event. Social Implications – This study aims to gain a better understanding of the residents’ attitudes of the cultural events hosted by the NMB, its Social Capital and its relationship with varying demographic niches and cultural-centric insights that align to the ideologies pertaining to global citizenship. Originality/Value – This present study makes a contribution to the theories of Social Capital and Stakeholder theory by investigating its roles in determining residents’ attitudes of cultural events in a city. Moreover, it discusses the role of the factors as inducing variables for residents’ motivation by employing marketing principles related to the unique and emotional selling proposition philosophy. Equally, the study espouses the significance of promoting cultural events to extent that it acts as a platform to promote socio-economic development; employment opportunities, improved living standards, improving city infrastructure and environmental protection of a destination and justifies the expedition of Social Capital on the attitudes of residents’.
- Full Text:
- Date Issued: 2016
Academic literacy and the decontextualised learner
- Boughey, Chrissie, McKenna, Sioux
- Authors: Boughey, Chrissie , McKenna, Sioux
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/64651 , vital:28585 , http://www.DOI:10.14426/cristal.v4i2.80
- Description: The literacy practices that are valued in the university emerge from specific disciplinary histories yet students are often expected to master these as if they were common sense and natural. This article argues that the autonomous model of literacy, which sees language use as the application of a set of neutral skills, continues to dominate in South African universities. This model denies the extent to which taking on disciplinary literacy practices can be difficult and have implications for identity. It also allows disciplinary norms to remain largely opaque and beyond critique. Furthermore, the autonomous model of literacy is often coupled with a discourse of the ‘decontextualised learner’ who is divorced from her social context, with higher education success seen to be resting largely upon attributes inherent in, or lacking from, the individual. Sadly, alternative critical social understandings have not been widely taken up despite their being well researched. Indeed, such understandings have often been misappropriated in ways that draw on critical social terminology to offer autonomous, decontextualised, remedial student interventions. We argue that these issues are implicated in students’ accusations that universities are alienating spaces.
- Full Text:
- Date Issued: 2016
- Authors: Boughey, Chrissie , McKenna, Sioux
- Date: 2016
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/64651 , vital:28585 , http://www.DOI:10.14426/cristal.v4i2.80
- Description: The literacy practices that are valued in the university emerge from specific disciplinary histories yet students are often expected to master these as if they were common sense and natural. This article argues that the autonomous model of literacy, which sees language use as the application of a set of neutral skills, continues to dominate in South African universities. This model denies the extent to which taking on disciplinary literacy practices can be difficult and have implications for identity. It also allows disciplinary norms to remain largely opaque and beyond critique. Furthermore, the autonomous model of literacy is often coupled with a discourse of the ‘decontextualised learner’ who is divorced from her social context, with higher education success seen to be resting largely upon attributes inherent in, or lacking from, the individual. Sadly, alternative critical social understandings have not been widely taken up despite their being well researched. Indeed, such understandings have often been misappropriated in ways that draw on critical social terminology to offer autonomous, decontextualised, remedial student interventions. We argue that these issues are implicated in students’ accusations that universities are alienating spaces.
- Full Text:
- Date Issued: 2016
The design of a Kaolin processing facility in Grahamstown, province of the Eastern Cape
- Authors: Bowles, Brendon Jerome
- Date: 2016
- Subjects: Architecture, Modern -- 21st century -- Designs and plans , Architecture -- South Africa -- Grahamstown -- Designs and plans , Industrial buildings -- South Africa -- Grahamstown -- Design and construction
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/15433 , vital:28245
- Description: The Story of clay in the Grahamstown area can be dated as far back as 1812. In 1823 there was conflict between the Xhosa and the British Settlers over clay pits at Coombs valley, an area outside Grahamstown towards East London (Holleman, 1997, p. 50). Since the initial conflict, the mining of the resource has become a commercial activity. Pottery industries, brick making facilities and a kaolin mill were opened, with brick making being the only economically sustained activity which continues to present day. With the largest known deposits of quality kaolin in South Africa, the economic condition of the context of Grahamstown is not benefitting from the abundance of the raw-clay material (Malatji, 2010). The material is currently being mined at Strowan mine, the most active mine in the area, approximately 4km from Grahamstown and is transported to Johannesburg for milling. The transport costs involved in moving the material from the mine to the mill has impeded potential production. In 1988 the production of Kaolin from the Grahamstown area accounted for 55% of total local production in South Africa, but that figure had dropped to 27% by 2008 (Horan, 2008, p.1). The high waste factor and the cost implication involved in the erecting of the required infrastructure and equipment for a mill, become the main impediment to erecting a new Kaolin mill in Grahamstown. The raw material which is milled has a waste factor of approximately 90 percent, meaning that; of the material mined in the open cast mining method, less than 10 percent is transported to be milled (Burchell, 2015). Capital gain from production of kaolin in relation to the cost of the mill is inadequate to financially sustain the costs of erecting a kaolin mill for Grahamstown. A need for a by-product to utilize the high waste content of the mined product in a waste resourceful manner will potentially sustain a new mill economically. With the problem of transport and foreign provincial exploitation of local resources, a kaolin mill for Grahamstown will increase production and potentially become a catalyst for future development around kaolin supporting industries such as ceramics, paper industries, cosmetics and pharmaceuticals. This treatise is a strategic approach towards the design of a Kaolin mill with a brick making factory as a by-product of the waste of the high quality kaolin.
- Full Text:
- Date Issued: 2016
- Authors: Bowles, Brendon Jerome
- Date: 2016
- Subjects: Architecture, Modern -- 21st century -- Designs and plans , Architecture -- South Africa -- Grahamstown -- Designs and plans , Industrial buildings -- South Africa -- Grahamstown -- Design and construction
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10948/15433 , vital:28245
- Description: The Story of clay in the Grahamstown area can be dated as far back as 1812. In 1823 there was conflict between the Xhosa and the British Settlers over clay pits at Coombs valley, an area outside Grahamstown towards East London (Holleman, 1997, p. 50). Since the initial conflict, the mining of the resource has become a commercial activity. Pottery industries, brick making facilities and a kaolin mill were opened, with brick making being the only economically sustained activity which continues to present day. With the largest known deposits of quality kaolin in South Africa, the economic condition of the context of Grahamstown is not benefitting from the abundance of the raw-clay material (Malatji, 2010). The material is currently being mined at Strowan mine, the most active mine in the area, approximately 4km from Grahamstown and is transported to Johannesburg for milling. The transport costs involved in moving the material from the mine to the mill has impeded potential production. In 1988 the production of Kaolin from the Grahamstown area accounted for 55% of total local production in South Africa, but that figure had dropped to 27% by 2008 (Horan, 2008, p.1). The high waste factor and the cost implication involved in the erecting of the required infrastructure and equipment for a mill, become the main impediment to erecting a new Kaolin mill in Grahamstown. The raw material which is milled has a waste factor of approximately 90 percent, meaning that; of the material mined in the open cast mining method, less than 10 percent is transported to be milled (Burchell, 2015). Capital gain from production of kaolin in relation to the cost of the mill is inadequate to financially sustain the costs of erecting a kaolin mill for Grahamstown. A need for a by-product to utilize the high waste content of the mined product in a waste resourceful manner will potentially sustain a new mill economically. With the problem of transport and foreign provincial exploitation of local resources, a kaolin mill for Grahamstown will increase production and potentially become a catalyst for future development around kaolin supporting industries such as ceramics, paper industries, cosmetics and pharmaceuticals. This treatise is a strategic approach towards the design of a Kaolin mill with a brick making factory as a by-product of the waste of the high quality kaolin.
- Full Text:
- Date Issued: 2016
Investigating the role of Hsp90 and LRP1 in FN matrix dynamics
- Authors: Boël, Natasha Marie-Eraine
- Date: 2016
- Subjects: Extracellular matrix , Molecular chaperones , Heat shock proteins , Cancer , Fibronectins
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/2713 , vital:20319
- Description: Fibronectin (FN), a matrix protein responsible for regulating processes including migration and differentiation, is secreted as a soluble dimer which is assembled into an insoluble extracellular matrix. The dynamics of FN matrix assembly and degradation play a large role in cell migration and invasion contributing to the metastatic potential of cancer cells. Previous studies from our group have shown the direct binding of Hsp90 and FN in vitro and that inhibition of Hsp90 with novobiocin (NOV) caused internalisation of the FN matrix. However, the receptor mediating this internalisation is currently unknown. Low density lipoprotein 1 (LRP1) is a likely candidate as it is a ubiquitous receptor responsible for regulating internalisation of diverse ligands and is known to bind both Hsp90 and FN. We used wild type and knockout LRP1 cell lines to study the endocytosis of FN via this receptor. Here, we demonstrate that LRP1-deficient cells accumulated greatly increased levels of FN and were found to be less sensitive to pharmacological inhibition of Hsp90 by NOV. LRP1-expressing MEF-1 and Hs578T breast cancer cells experienced an increase in total FN in response to NOV, at concentrations below the EC50 value, followed by a dose-dependent loss of FN. We attributed greater FN levels to a loss of extracellular FN matrix coupled with increased internalisation of FN. Cell-surface biotinylation and DOC assays showed that loss of extracellular FN was specific to LRP1-expressing MEF-1 cells. Furthermore, we demonstrate that the loss of extracellular FN is not affected by changes in FN mRNA levels as determined by qRT-PCR, and that treatment with NOV resulted in the accelerated degradation of FN in the presence of cycloheximide. Immunoprecipitation studies reveal a putative complex exists between FN, Hsp90 and LRP1 in both cancer and non-cancer cells which is not perturbed by NOV. Western analyses revealed increased proteolytic processing of LRP1 in response to NOV which we proposed, based on literature, to modulate signalling pathways as a potential mechanism for regulating FN turnover. Moreover, using wound healing assays we identified increased migration to be one of the consequences associated with loss of extracellular FN by Hsp90 inhibition but only in cells containing LRP1. In summary, this study provides new insights into the Hsp90-LRP1 mediated loss of FN matrix and also reveals for the first time the functional consequence related to FN turnover by NOV was an increase in migration in LRP1-expressing cells.
- Full Text:
- Date Issued: 2016
- Authors: Boël, Natasha Marie-Eraine
- Date: 2016
- Subjects: Extracellular matrix , Molecular chaperones , Heat shock proteins , Cancer , Fibronectins
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/2713 , vital:20319
- Description: Fibronectin (FN), a matrix protein responsible for regulating processes including migration and differentiation, is secreted as a soluble dimer which is assembled into an insoluble extracellular matrix. The dynamics of FN matrix assembly and degradation play a large role in cell migration and invasion contributing to the metastatic potential of cancer cells. Previous studies from our group have shown the direct binding of Hsp90 and FN in vitro and that inhibition of Hsp90 with novobiocin (NOV) caused internalisation of the FN matrix. However, the receptor mediating this internalisation is currently unknown. Low density lipoprotein 1 (LRP1) is a likely candidate as it is a ubiquitous receptor responsible for regulating internalisation of diverse ligands and is known to bind both Hsp90 and FN. We used wild type and knockout LRP1 cell lines to study the endocytosis of FN via this receptor. Here, we demonstrate that LRP1-deficient cells accumulated greatly increased levels of FN and were found to be less sensitive to pharmacological inhibition of Hsp90 by NOV. LRP1-expressing MEF-1 and Hs578T breast cancer cells experienced an increase in total FN in response to NOV, at concentrations below the EC50 value, followed by a dose-dependent loss of FN. We attributed greater FN levels to a loss of extracellular FN matrix coupled with increased internalisation of FN. Cell-surface biotinylation and DOC assays showed that loss of extracellular FN was specific to LRP1-expressing MEF-1 cells. Furthermore, we demonstrate that the loss of extracellular FN is not affected by changes in FN mRNA levels as determined by qRT-PCR, and that treatment with NOV resulted in the accelerated degradation of FN in the presence of cycloheximide. Immunoprecipitation studies reveal a putative complex exists between FN, Hsp90 and LRP1 in both cancer and non-cancer cells which is not perturbed by NOV. Western analyses revealed increased proteolytic processing of LRP1 in response to NOV which we proposed, based on literature, to modulate signalling pathways as a potential mechanism for regulating FN turnover. Moreover, using wound healing assays we identified increased migration to be one of the consequences associated with loss of extracellular FN by Hsp90 inhibition but only in cells containing LRP1. In summary, this study provides new insights into the Hsp90-LRP1 mediated loss of FN matrix and also reveals for the first time the functional consequence related to FN turnover by NOV was an increase in migration in LRP1-expressing cells.
- Full Text:
- Date Issued: 2016
The voice of the child in parental divorce: a narrative inquiry
- Authors: Brand, Carrie
- Date: 2016
- Subjects: Conversation analysis , Children of divorced parents , Divorced parents
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/8923 , vital:26443
- Description: Parental divorce is considered one of the most stressful events in the lives of children. The adult perspective has dominated the discourse on divorce, and only recently has research started to consider the viewpoint of children. Research indicates that the nature of the divorce process as experienced by the child is the most important factor in post-divorce adjustment. It also remains a relatively unexplored area, with research on the manner in which children experience the divorce process being limited. The current study aimed to conduct a narrative inquiry into the experiences and perceptions of parental divorce, of a purposive sample of 9 to 10 year old children. The primary aim of the study was to highlight and honour the voice of the child in a parental divorce process. The current research was qualitative in nature and adopted a narrative paradigm. Five children were interviewed qualitatively using an unstructured interview. Data were analysed using thematic analysis. Seven themes were identified. The first theme explored children’s endeavours to describe and explain parental divorce. An additional six themes were developed around the types of stories children told of the divorce process. Themes included, What is a Divorcement, Stories of Loss, Stories of Gain, Stories of Change, Stories of Stability, Healing Stories, and Complicating Stories. This study endeavoured to provide divorced parents and those working with children a greater understanding of the way in which children perceive parental divorce, and insight into the factors that facilitate children’s positive adjustment to parental divorce.
- Full Text:
- Date Issued: 2016
- Authors: Brand, Carrie
- Date: 2016
- Subjects: Conversation analysis , Children of divorced parents , Divorced parents
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/8923 , vital:26443
- Description: Parental divorce is considered one of the most stressful events in the lives of children. The adult perspective has dominated the discourse on divorce, and only recently has research started to consider the viewpoint of children. Research indicates that the nature of the divorce process as experienced by the child is the most important factor in post-divorce adjustment. It also remains a relatively unexplored area, with research on the manner in which children experience the divorce process being limited. The current study aimed to conduct a narrative inquiry into the experiences and perceptions of parental divorce, of a purposive sample of 9 to 10 year old children. The primary aim of the study was to highlight and honour the voice of the child in a parental divorce process. The current research was qualitative in nature and adopted a narrative paradigm. Five children were interviewed qualitatively using an unstructured interview. Data were analysed using thematic analysis. Seven themes were identified. The first theme explored children’s endeavours to describe and explain parental divorce. An additional six themes were developed around the types of stories children told of the divorce process. Themes included, What is a Divorcement, Stories of Loss, Stories of Gain, Stories of Change, Stories of Stability, Healing Stories, and Complicating Stories. This study endeavoured to provide divorced parents and those working with children a greater understanding of the way in which children perceive parental divorce, and insight into the factors that facilitate children’s positive adjustment to parental divorce.
- Full Text:
- Date Issued: 2016