Evaluating the cyber security skills gap relating to penetration testing
- Authors: Beukes, Dirk Johannes
- Date: 2021
- Subjects: Computer networks -- Security measures , Computer networks -- Monitoring , Computer networks -- Management , Data protection , Information technology -- Security measures , Professionals -- Supply and demand , Electronic data personnel -- Supply and demand
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/171120 , vital:42021
- Description: Information Technology (IT) is growing rapidly and has become an integral part of daily life. It provides a boundless list of services and opportunities, generating boundless sources of information, which could be abused or exploited. Due to this growth, there are thousands of new users added to the grid using computer systems in a static and mobile environment; this fact alone creates endless volumes of data to be exploited and hardware devices to be abused by the wrong people. The growth in the IT environment adds challenges that may affect users in their personal, professional, and business lives. There are constant threats on corporate and private computer networks and computer systems. In the corporate environment companies try to eliminate the threat by testing networks making use of penetration tests and by implementing cyber awareness programs to make employees more aware of the cyber threat. Penetration tests and vulnerability assessments are undervalued; are seen as a formality and are not used to increase system security. If used regularly the computer system will be more secure and attacks minimized. With the growth in technology, industries all over the globe become fully dependent on information systems in doing their day-to-day business. As technology evolves and new technology becomes available, the bigger the risk becomes to protect against the dangers which come with this new technology. For industry to protect itself against this growth in technology, personnel with a certain skill set is needed. This is where cyber security plays a very important role in the protection of information systems to ensure the confidentiality, integrity and availability of the information system itself and the data on the system. Due to this drive to secure information systems, the need for cyber security by professionals is on the rise as well. It is estimated that there is a shortage of one million cyber security professionals globally. What is the reason for this skills shortage? Will it be possible to close this skills shortage gap? This study is about identifying the skills gap and identifying possible ways to close this skills gap. In this study, research was conducted on the cyber security international standards, cyber security training at universities and international certification focusing specifically on penetration testing, the evaluation of the need of industry while recruiting new penetration testers, finishing with suggestions on how to fill possible gaps in the skills market with a conclusion.
- Full Text:
- Date Issued: 2021
- Authors: Beukes, Dirk Johannes
- Date: 2021
- Subjects: Computer networks -- Security measures , Computer networks -- Monitoring , Computer networks -- Management , Data protection , Information technology -- Security measures , Professionals -- Supply and demand , Electronic data personnel -- Supply and demand
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/171120 , vital:42021
- Description: Information Technology (IT) is growing rapidly and has become an integral part of daily life. It provides a boundless list of services and opportunities, generating boundless sources of information, which could be abused or exploited. Due to this growth, there are thousands of new users added to the grid using computer systems in a static and mobile environment; this fact alone creates endless volumes of data to be exploited and hardware devices to be abused by the wrong people. The growth in the IT environment adds challenges that may affect users in their personal, professional, and business lives. There are constant threats on corporate and private computer networks and computer systems. In the corporate environment companies try to eliminate the threat by testing networks making use of penetration tests and by implementing cyber awareness programs to make employees more aware of the cyber threat. Penetration tests and vulnerability assessments are undervalued; are seen as a formality and are not used to increase system security. If used regularly the computer system will be more secure and attacks minimized. With the growth in technology, industries all over the globe become fully dependent on information systems in doing their day-to-day business. As technology evolves and new technology becomes available, the bigger the risk becomes to protect against the dangers which come with this new technology. For industry to protect itself against this growth in technology, personnel with a certain skill set is needed. This is where cyber security plays a very important role in the protection of information systems to ensure the confidentiality, integrity and availability of the information system itself and the data on the system. Due to this drive to secure information systems, the need for cyber security by professionals is on the rise as well. It is estimated that there is a shortage of one million cyber security professionals globally. What is the reason for this skills shortage? Will it be possible to close this skills shortage gap? This study is about identifying the skills gap and identifying possible ways to close this skills gap. In this study, research was conducted on the cyber security international standards, cyber security training at universities and international certification focusing specifically on penetration testing, the evaluation of the need of industry while recruiting new penetration testers, finishing with suggestions on how to fill possible gaps in the skills market with a conclusion.
- Full Text:
- Date Issued: 2021
Evaluation of metallophthalocyanine functionalized photocatalytic asymmetric polymer membranes for pollution control and antimicrobial activity
- Mafukidze, Donovan Musizvinoda Chidyamurimi
- Authors: Mafukidze, Donovan Musizvinoda Chidyamurimi
- Date: 2021
- Subjects: Photosensitizing compounds , Water -- Purification -- Photocatalysis , Phthalocyanines , Polymeric membranes , Porphyrins
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/171357 , vital:42052 , 10.21504/10962/171357
- Description: The conceptualisation of photosensitizing water treatment polymer membranes using phthalocyanine based photosensitizers is reported in this thesis. The key to successful preparation of stable photoactive polymer membranes was established as the covalent anchorage of the photosensitizer to a polymer, which was proven by singlet oxygen generation by the membranes without photosensitizer deterioration. Despite this limitation, the covalent linkage-incapable unsubstituted zinc (II) phthalocyanine (complex 2) was applied as a nanoconjugate of graphene quantum dots (2π(GQDs)). 2π(GQDs) was formed through π-π stacking, and was then covalently anchored, as a proof of concept. This concept was also applied to 2-(4-carboxyphenoxy) phthalocyaninato zinc (II) (complex 3) which is capable of covalent linkage but proved to deteriorate the efficiency of singlet oxygen formation with comparison to the covalent conjugates. Singlet oxygen generation by functionalized polymer membranes rendered them photocatalytic in the degradation of organic pollutants and microorganisms in water. Organic pollutant degradation capability was exemplified by 2π(GQDs) and a porphyrin-phthalocyanine heterodyad (complex 10) functionalized membranes (2π(GQDs)-memb and 10-memb respectively), where a MPc loading of approximately 0.139 μmol MPc/g of membrane was able to achieve a 4-chlorophenol degradation rate of 3.77 × 10−6 mol L−1 min−1 in a second order reaction with an initial 4-chlorophenol concentration of 3.24 × 10−4 mol L−1 for 2π(GQDs)-memb as an example. Antibacterial studies against S.aureus using a quaternized MPc and conjugates of silver triangular nanoprisms with zinc (II) and indium (III) MPcs showed note-worthy improvements in photodynamic antimicrobial chemotherapy (PACT) activity in comparison to the unquaternized MPc precursor, and the free zinc and indium MPcs respectively. Functionalization of polymer membranes with these higher activity photosensitizers translated to the formation of potentially superior biological fouling resistant membranes. The use of porphyrin-phthalocyanine polynuclei arrays (complex 10) in polymer membrane functionalization resulted in the use of a wider wavelength range (white light). The findings from this work as a whole, thus presents the potential applicability of phthalocyanine functionalized polymer membranes in water treatment technology.
- Full Text:
- Date Issued: 2021
- Authors: Mafukidze, Donovan Musizvinoda Chidyamurimi
- Date: 2021
- Subjects: Photosensitizing compounds , Water -- Purification -- Photocatalysis , Phthalocyanines , Polymeric membranes , Porphyrins
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/171357 , vital:42052 , 10.21504/10962/171357
- Description: The conceptualisation of photosensitizing water treatment polymer membranes using phthalocyanine based photosensitizers is reported in this thesis. The key to successful preparation of stable photoactive polymer membranes was established as the covalent anchorage of the photosensitizer to a polymer, which was proven by singlet oxygen generation by the membranes without photosensitizer deterioration. Despite this limitation, the covalent linkage-incapable unsubstituted zinc (II) phthalocyanine (complex 2) was applied as a nanoconjugate of graphene quantum dots (2π(GQDs)). 2π(GQDs) was formed through π-π stacking, and was then covalently anchored, as a proof of concept. This concept was also applied to 2-(4-carboxyphenoxy) phthalocyaninato zinc (II) (complex 3) which is capable of covalent linkage but proved to deteriorate the efficiency of singlet oxygen formation with comparison to the covalent conjugates. Singlet oxygen generation by functionalized polymer membranes rendered them photocatalytic in the degradation of organic pollutants and microorganisms in water. Organic pollutant degradation capability was exemplified by 2π(GQDs) and a porphyrin-phthalocyanine heterodyad (complex 10) functionalized membranes (2π(GQDs)-memb and 10-memb respectively), where a MPc loading of approximately 0.139 μmol MPc/g of membrane was able to achieve a 4-chlorophenol degradation rate of 3.77 × 10−6 mol L−1 min−1 in a second order reaction with an initial 4-chlorophenol concentration of 3.24 × 10−4 mol L−1 for 2π(GQDs)-memb as an example. Antibacterial studies against S.aureus using a quaternized MPc and conjugates of silver triangular nanoprisms with zinc (II) and indium (III) MPcs showed note-worthy improvements in photodynamic antimicrobial chemotherapy (PACT) activity in comparison to the unquaternized MPc precursor, and the free zinc and indium MPcs respectively. Functionalization of polymer membranes with these higher activity photosensitizers translated to the formation of potentially superior biological fouling resistant membranes. The use of porphyrin-phthalocyanine polynuclei arrays (complex 10) in polymer membrane functionalization resulted in the use of a wider wavelength range (white light). The findings from this work as a whole, thus presents the potential applicability of phthalocyanine functionalized polymer membranes in water treatment technology.
- Full Text:
- Date Issued: 2021
Exploring domestic workers’ subjectivities through stories of their personal childcare arrangements
- Authors: Michaeu, Nisha
- Date: 2021
- Subjects: Women household employees, Black -- Social conditions -- South Africa , Women household employees, Black -- Social conditions -- South Africa -- Case studies , Women household employees, Black -- Psychology -- South Africa , Day care aides -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/172029 , vital:42150
- Description: Domestic service has long been a major sector of the South African labour market, for black women particularly, who must support their family and children. Existing research has stressed the way in which race, class and gender has shaped the oppressive character of domestic service in South Africa. In this narrative study a new slant is provided on this existing theoretical discussion of domestic labour, one that is focused on exploring the agentic human being beyond ‘the servant question’. This study uses narrative interviews with domestic workers in Makhanda/Grahamstown in the Eastern Cape province of South Africa to show how we can expand on potentially limited or constricted passive ‘domestic worker identities’ and ideas/beliefs about women who do domestic work. A performative and positioning narrative analysis is used to explore the subject positions of domestic workers in their stories about their childcare arrangements. This analysis examines multiple shifting identities and positions that are used by domestic workers in relation to their maternal subjectivity and their audience (here, a white trainee-psychologist esearcher), while highlighting the significance of narrative methodology in making these positions visible. The areas of focus were their history, experience of domestic work, life outside of domestic work, family network/dynamics and personal childcare arrangements. Under these areas of focus the following was analysed: the ways in which the storyteller positioned herself in her narrative, how she compared/contrasted or located herself in relation to the other, claims of identity that were made, what she incorporated or purposefully left out, words and phrases that were chosen, which sections of talk were embellished or elaborated on and appeals that were made to the interviewer (Riessman, 2002). Through exploring the micro-practices of domestic workers’ lives the study found that there were various subject positions constructed and used by this group of women. Findings showed that domestic workers positioned themselves actively as breadwinners, good mothers who give their children opportunities that they were not given, nurturers and crafty mothers who secure good care for their children. In contrast to these active subject positions, positions of sacrifice were performed when domestic workers spoke about leaving their young children in the care of another while they worked. The study also found that participants managed complex positions of disappointment and unmet expectations for a better life in the new South Africa by using narratives of resistance and agency. In certain instances, identity appeals were made to the interviewer that they, and other women who do domestic work, are entrepreneurial and creative with their income and possess skills outside of their day-to-day household cleaning jobs. This was interpreted as an attempt to extend the domestic worker identity positioning beyond the traditionally accepted notions of unskilled/uneducated women who do domestic work. In the study this allowed for more subject positions to be taken up in terms of identities and selves, beyond just being a “domestic worker”.
- Full Text:
- Date Issued: 2021
- Authors: Michaeu, Nisha
- Date: 2021
- Subjects: Women household employees, Black -- Social conditions -- South Africa , Women household employees, Black -- Social conditions -- South Africa -- Case studies , Women household employees, Black -- Psychology -- South Africa , Day care aides -- South Africa
- Language: English
- Type: text , Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/172029 , vital:42150
- Description: Domestic service has long been a major sector of the South African labour market, for black women particularly, who must support their family and children. Existing research has stressed the way in which race, class and gender has shaped the oppressive character of domestic service in South Africa. In this narrative study a new slant is provided on this existing theoretical discussion of domestic labour, one that is focused on exploring the agentic human being beyond ‘the servant question’. This study uses narrative interviews with domestic workers in Makhanda/Grahamstown in the Eastern Cape province of South Africa to show how we can expand on potentially limited or constricted passive ‘domestic worker identities’ and ideas/beliefs about women who do domestic work. A performative and positioning narrative analysis is used to explore the subject positions of domestic workers in their stories about their childcare arrangements. This analysis examines multiple shifting identities and positions that are used by domestic workers in relation to their maternal subjectivity and their audience (here, a white trainee-psychologist esearcher), while highlighting the significance of narrative methodology in making these positions visible. The areas of focus were their history, experience of domestic work, life outside of domestic work, family network/dynamics and personal childcare arrangements. Under these areas of focus the following was analysed: the ways in which the storyteller positioned herself in her narrative, how she compared/contrasted or located herself in relation to the other, claims of identity that were made, what she incorporated or purposefully left out, words and phrases that were chosen, which sections of talk were embellished or elaborated on and appeals that were made to the interviewer (Riessman, 2002). Through exploring the micro-practices of domestic workers’ lives the study found that there were various subject positions constructed and used by this group of women. Findings showed that domestic workers positioned themselves actively as breadwinners, good mothers who give their children opportunities that they were not given, nurturers and crafty mothers who secure good care for their children. In contrast to these active subject positions, positions of sacrifice were performed when domestic workers spoke about leaving their young children in the care of another while they worked. The study also found that participants managed complex positions of disappointment and unmet expectations for a better life in the new South Africa by using narratives of resistance and agency. In certain instances, identity appeals were made to the interviewer that they, and other women who do domestic work, are entrepreneurial and creative with their income and possess skills outside of their day-to-day household cleaning jobs. This was interpreted as an attempt to extend the domestic worker identity positioning beyond the traditionally accepted notions of unskilled/uneducated women who do domestic work. In the study this allowed for more subject positions to be taken up in terms of identities and selves, beyond just being a “domestic worker”.
- Full Text:
- Date Issued: 2021
Exploring the role of supervisors in developing employee commitment in a Namibian Public Institution from the subordinates’ perspective
- Authors: Daniel, Anna
- Date: 2021
- Subjects: Supervisors -- Namibia -- Case studies , Leadership -- Namibia -- Case studies , Employee motivation -- Namibia -- Case studies , Employee loyalty -- Namibia -- Case studies , Supervision -- Namibia -- Case studies , Management -- Employee participation -- Namibia -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/170770 , vital:41958
- Description: Over the years, scholars have noted the importance of organisations managing the performance of their employees by effectively maintaining their commitment. Hence, l ite rature highlighted that employee s have the potential to be recognised as a source of competitive advantage for an organisation and not a resource of an organisation. The main aim of the study was to explore the role of supervisors in developing employee commitment in a Namibian Public Ins titution from the subordinates’ perspective. The focus of this research was to understand how subordinates were included in decision making and were supported by their supervisors , and on how subordinates received feed b ack on role fulfilment and performance from their supervisors. Furthermore, the study described how subordinates viewed the leadership behaviour of their supervisors and how this i nfluenced employee commitment. The data was collected using qualitative me t hods through semi - structured face - to - face interview s with the subordinates of the selected institution. During this study, a sample of 15 subordinates taken from a population of 266 within the institution’s structure was inte rviewed . The interview quest ion s were based on how supervisors included subordinates in decision making, developed subordinates ’ support and delivered feedback on role and performance. The study used secondary data to determine the level of performance against set targets of the inst itu tion, using the annual performance report of the institution. In addition , the study used the staff access control syste m to determine the work time s of employees Lastly, the study analysed the data regarding staff resignation for the last five years to a ssess the level of staff turnover rate of the institution. The study f ound that the subordinates felt the re should be greater subordinate inclusion in decision making, increased levels of re gular feedback and higher levels of support shown by supervis ors t o subordinates when e xecuting their jobs. The study further highlighted the importance of supervisors to develop the ability of shifting from one leadership style to another depending on the situation at hand. The study reviewed six leadership style s that could influence commitment . Therefore, the study recommend s th at the institution direct its attention towards developing the situational leadership skills of their supervisors and developing their skills to enable them to better harmonise teamwork, increas e regular communication and give regular feedback to their subordinates . The results from this research will be beneficial to public institutions within the region and will, in add ition, enhance the academic body of literature in this field . The s tudy will draw the attention of supervisors to the importance of their behaviour, conduct, and their subsequent impact on employee commitment.
- Full Text:
- Date Issued: 2021
- Authors: Daniel, Anna
- Date: 2021
- Subjects: Supervisors -- Namibia -- Case studies , Leadership -- Namibia -- Case studies , Employee motivation -- Namibia -- Case studies , Employee loyalty -- Namibia -- Case studies , Supervision -- Namibia -- Case studies , Management -- Employee participation -- Namibia -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/170770 , vital:41958
- Description: Over the years, scholars have noted the importance of organisations managing the performance of their employees by effectively maintaining their commitment. Hence, l ite rature highlighted that employee s have the potential to be recognised as a source of competitive advantage for an organisation and not a resource of an organisation. The main aim of the study was to explore the role of supervisors in developing employee commitment in a Namibian Public Ins titution from the subordinates’ perspective. The focus of this research was to understand how subordinates were included in decision making and were supported by their supervisors , and on how subordinates received feed b ack on role fulfilment and performance from their supervisors. Furthermore, the study described how subordinates viewed the leadership behaviour of their supervisors and how this i nfluenced employee commitment. The data was collected using qualitative me t hods through semi - structured face - to - face interview s with the subordinates of the selected institution. During this study, a sample of 15 subordinates taken from a population of 266 within the institution’s structure was inte rviewed . The interview quest ion s were based on how supervisors included subordinates in decision making, developed subordinates ’ support and delivered feedback on role and performance. The study used secondary data to determine the level of performance against set targets of the inst itu tion, using the annual performance report of the institution. In addition , the study used the staff access control syste m to determine the work time s of employees Lastly, the study analysed the data regarding staff resignation for the last five years to a ssess the level of staff turnover rate of the institution. The study f ound that the subordinates felt the re should be greater subordinate inclusion in decision making, increased levels of re gular feedback and higher levels of support shown by supervis ors t o subordinates when e xecuting their jobs. The study further highlighted the importance of supervisors to develop the ability of shifting from one leadership style to another depending on the situation at hand. The study reviewed six leadership style s that could influence commitment . Therefore, the study recommend s th at the institution direct its attention towards developing the situational leadership skills of their supervisors and developing their skills to enable them to better harmonise teamwork, increas e regular communication and give regular feedback to their subordinates . The results from this research will be beneficial to public institutions within the region and will, in add ition, enhance the academic body of literature in this field . The s tudy will draw the attention of supervisors to the importance of their behaviour, conduct, and their subsequent impact on employee commitment.
- Full Text:
- Date Issued: 2021
High-resolution geological, petrological and geochemical investigation of the mid mid-lower c. 3.3 Ga Kromberg type type-section, Barberton greenstone belt, South Africa Africa
- Authors: Ndlela, Sibusisiwe
- Date: 2021
- Subjects: Petrology -- Eswatini and South Africa -- Barberton Greenstone Belt , Geology -- Eswatini and South Africa -- Barberton Greenstone Belt , Geochemistry -- Eswatini and South Africa -- Barberton Greenstone Belt , Onverwacht Group (South Africa) , Barberton Greenstone Belt (Eswatini and South Africa) , Groups (Stratigraph) -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/172241 , vital:42179
- Description: The geology of the SE limb of the Kromberg type-section, its origin and its evolution has remained controversial for more than five decades since its discovery by Viljoen and Viljoen (1969). Different lithostratigraphy and geodynamic models have been proposed that were centred around two end-member models, a continuous layer-cake stratigraphy model (Viljoen and Viljoen, 1969c, Lowe et al., 1999) or a tectono-stratigraphic model (de Wit et al., 2011, Furnes et al., 2012). Additionally, the Kromberg type-section mafic-ultramafic sequence represents a relatively thin, dismembered sequence compared to other formations or ‘complexes’ in the Onverwacht Group. Previous geology workers relied on the field interpretations for the construction of the geological architecture of the Kromberg type-section; but no petrographic analyses were conducted for accurate, integrated geological characterization of different rock compositions. To address controversies centred around the Kromberg type-section geology and geodynamic setting, this study is aimed at testing previously proposed stratigraphic and geodynamic models by integrating high-resolution geological mapping, petrography, mineral chemistry and whole-rock geochemistry to verify rock characterization. The aim is to accurately reconstruct the volcano-sedimentary architecture of the Kromberg type-section and to compare this to the results of previous fieldwork. Moreover, the manner in which the Kromberg sequence may relate to current Archean geodynamic models is evaluated, and a new model explaining the origin and evolution of the Kromberg type sequence is proposed. The integration of high-resolution field mapping, petrography and geochemistry has allowed for a high precision study and that has resulted in the construction of a new geological architecture for the SE limb of the Kromberg type-section. The stratigraphic thickness of the SE limb of the Kromberg sequence comprises dominant c. 80% volcanic rocks and minor c. 15% intrusive rocks, intercalated by 7 volcano-sedimentary chert horizons (c. 5%). Four main rock types (groups) are present in the Kromberg type-section with two sub-types of komatiitic basalts (the Badplaas-type and Geluk-types), Fe-rich tholeiitic basalt, cumulate peridotite, and a metadunite. Although the Kromberg type-section records sub-greenschist to lower greenschist facies, more than 50% of the rock samples classify as altered with parts of the stratigraphy recording extensive chloritization and severe ocean-floor silicification. Geochemical data revealed an enrichment in SiO2, K2O, Ba, Rb and variation in HREE for highly silicified samples whereas, chloritized samples are enriched in FeO and have concave upward LREE patterns. Partially chloritized tholeiites and komatiitic basalts have overlapping SiO2 signatures, relatively flat REE patterns and a small negative Nb anomaly in the primitive mantle-normalized spider diagrams. This thesis provides the first Lu-Hf isotope data on whole rock samples from the Kromberg type-section. The εHf values at t=3.33 Ga range between -0.62 to +4.18 and Hf model ages range between 3.43 - 4.27 Ga. The rock compositions are compared to the geochemistry of other greenstone belt rocks, which are considered to provide insight onto the geodynamic setting under which the Kromberg mafic-ultramafic sequence formed. The rock compositions reveal plume-related processes where a primitive mantle melt interacts with recycled mafic crust or mafic lower crust of older units of the Onverwacht Group. Only a small Nb anomaly is found in some samples and the data plots outside the subduction zone (forearc and back-arc) field. Rare-Earth element profiles are flat and not consistent with a subduction zone signature, as proposed in previous studies. Rifting of an oceanic floor in a juvenile basin is proposed for the formation of the Kromberg type-section rocks, prior to being tectonically accreted during regional transpressional deformation at c. 3.23 Ga.
- Full Text:
- Date Issued: 2021
- Authors: Ndlela, Sibusisiwe
- Date: 2021
- Subjects: Petrology -- Eswatini and South Africa -- Barberton Greenstone Belt , Geology -- Eswatini and South Africa -- Barberton Greenstone Belt , Geochemistry -- Eswatini and South Africa -- Barberton Greenstone Belt , Onverwacht Group (South Africa) , Barberton Greenstone Belt (Eswatini and South Africa) , Groups (Stratigraph) -- South Africa
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/172241 , vital:42179
- Description: The geology of the SE limb of the Kromberg type-section, its origin and its evolution has remained controversial for more than five decades since its discovery by Viljoen and Viljoen (1969). Different lithostratigraphy and geodynamic models have been proposed that were centred around two end-member models, a continuous layer-cake stratigraphy model (Viljoen and Viljoen, 1969c, Lowe et al., 1999) or a tectono-stratigraphic model (de Wit et al., 2011, Furnes et al., 2012). Additionally, the Kromberg type-section mafic-ultramafic sequence represents a relatively thin, dismembered sequence compared to other formations or ‘complexes’ in the Onverwacht Group. Previous geology workers relied on the field interpretations for the construction of the geological architecture of the Kromberg type-section; but no petrographic analyses were conducted for accurate, integrated geological characterization of different rock compositions. To address controversies centred around the Kromberg type-section geology and geodynamic setting, this study is aimed at testing previously proposed stratigraphic and geodynamic models by integrating high-resolution geological mapping, petrography, mineral chemistry and whole-rock geochemistry to verify rock characterization. The aim is to accurately reconstruct the volcano-sedimentary architecture of the Kromberg type-section and to compare this to the results of previous fieldwork. Moreover, the manner in which the Kromberg sequence may relate to current Archean geodynamic models is evaluated, and a new model explaining the origin and evolution of the Kromberg type sequence is proposed. The integration of high-resolution field mapping, petrography and geochemistry has allowed for a high precision study and that has resulted in the construction of a new geological architecture for the SE limb of the Kromberg type-section. The stratigraphic thickness of the SE limb of the Kromberg sequence comprises dominant c. 80% volcanic rocks and minor c. 15% intrusive rocks, intercalated by 7 volcano-sedimentary chert horizons (c. 5%). Four main rock types (groups) are present in the Kromberg type-section with two sub-types of komatiitic basalts (the Badplaas-type and Geluk-types), Fe-rich tholeiitic basalt, cumulate peridotite, and a metadunite. Although the Kromberg type-section records sub-greenschist to lower greenschist facies, more than 50% of the rock samples classify as altered with parts of the stratigraphy recording extensive chloritization and severe ocean-floor silicification. Geochemical data revealed an enrichment in SiO2, K2O, Ba, Rb and variation in HREE for highly silicified samples whereas, chloritized samples are enriched in FeO and have concave upward LREE patterns. Partially chloritized tholeiites and komatiitic basalts have overlapping SiO2 signatures, relatively flat REE patterns and a small negative Nb anomaly in the primitive mantle-normalized spider diagrams. This thesis provides the first Lu-Hf isotope data on whole rock samples from the Kromberg type-section. The εHf values at t=3.33 Ga range between -0.62 to +4.18 and Hf model ages range between 3.43 - 4.27 Ga. The rock compositions are compared to the geochemistry of other greenstone belt rocks, which are considered to provide insight onto the geodynamic setting under which the Kromberg mafic-ultramafic sequence formed. The rock compositions reveal plume-related processes where a primitive mantle melt interacts with recycled mafic crust or mafic lower crust of older units of the Onverwacht Group. Only a small Nb anomaly is found in some samples and the data plots outside the subduction zone (forearc and back-arc) field. Rare-Earth element profiles are flat and not consistent with a subduction zone signature, as proposed in previous studies. Rifting of an oceanic floor in a juvenile basin is proposed for the formation of the Kromberg type-section rocks, prior to being tectonically accreted during regional transpressional deformation at c. 3.23 Ga.
- Full Text:
- Date Issued: 2021
How art-as-therapy supports participants with a diagnosis of schizophrenia : a phenomenological investigation
- Authors: Mitchell, Julia L G
- Date: 2021
- Subjects: Schizophrenia -- Treatment , Schizophrenia -- Treatment -- South Africa -- Case studies , Art Therapy , Art Therapy -- South Africa -- Case studies , Stormberg Hospital (Eastern Cape, South Africa)
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172157 , vital:42171 , 10.21504/10962/172157
- Description: Although art therapy is recommended in management programmes for individuals with a diagnosis of schizophrenia, calls have been made for more detailed explanations as to how artmaking is working. This study responds to those calls by considering the artmaking experiences of 15 mental health users with a diagnosis of schizophrenia, resident at a forensic, mental health facility in South Africa. A phenomenological approach was chosen because of its focus on lived experiences, suited to explore the embodied and pre-reflective experience of studio-based artmaking. Dialogical and narrative understandings were subsequently incorporated to account for more reflective aspects of the artmaking experience. Two main participant descriptions of artmaking, centring on feeling at home and on doing something meaningful, guided the phenomenological lifeworld method in analysing the data (interviews, artworks and field observations in art groups and exhibitions), along selected dimensions of lived experience, namely embodiment, temporality, spatiality, sociality and selfhood. These findings lend support to new phenomenological research which suggests that artmaking intersects with disrupted abilities for perceptual engagement underlying manifestations of schizophrenia symptomology. This research supports assertions that artmaking has the potential to support the minimal sense of self and expand possibilities for renewed embodied and more reflective meaning-making. Explanations of findings centred around the distinct artistic style of each participant, as well as their artworks which revealed individual lifeworlds including a variety of self-positions. The inherent properties of the completed artworks also provided possibilities for renewed experiences of sociality. Additional support for the findings is drawn from recent research in the fields of early neurodevelopmental trauma, and trauma research findings within the art therapy field.
- Full Text:
- Date Issued: 2021
- Authors: Mitchell, Julia L G
- Date: 2021
- Subjects: Schizophrenia -- Treatment , Schizophrenia -- Treatment -- South Africa -- Case studies , Art Therapy , Art Therapy -- South Africa -- Case studies , Stormberg Hospital (Eastern Cape, South Africa)
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172157 , vital:42171 , 10.21504/10962/172157
- Description: Although art therapy is recommended in management programmes for individuals with a diagnosis of schizophrenia, calls have been made for more detailed explanations as to how artmaking is working. This study responds to those calls by considering the artmaking experiences of 15 mental health users with a diagnosis of schizophrenia, resident at a forensic, mental health facility in South Africa. A phenomenological approach was chosen because of its focus on lived experiences, suited to explore the embodied and pre-reflective experience of studio-based artmaking. Dialogical and narrative understandings were subsequently incorporated to account for more reflective aspects of the artmaking experience. Two main participant descriptions of artmaking, centring on feeling at home and on doing something meaningful, guided the phenomenological lifeworld method in analysing the data (interviews, artworks and field observations in art groups and exhibitions), along selected dimensions of lived experience, namely embodiment, temporality, spatiality, sociality and selfhood. These findings lend support to new phenomenological research which suggests that artmaking intersects with disrupted abilities for perceptual engagement underlying manifestations of schizophrenia symptomology. This research supports assertions that artmaking has the potential to support the minimal sense of self and expand possibilities for renewed embodied and more reflective meaning-making. Explanations of findings centred around the distinct artistic style of each participant, as well as their artworks which revealed individual lifeworlds including a variety of self-positions. The inherent properties of the completed artworks also provided possibilities for renewed experiences of sociality. Additional support for the findings is drawn from recent research in the fields of early neurodevelopmental trauma, and trauma research findings within the art therapy field.
- Full Text:
- Date Issued: 2021
How the leaders of an Eastern Cape development agency experienced a transition from specialist roles to the leadership roles and how this shaped their leadership identity
- Authors: Mbokoma, Noxolo Patricia
- Date: 2021
- Subjects: Economic development projects -- Managemenat -- South Africa -- Case studies , Organizational change -- South Africa -- Case studies , Organizational behavior -- South Africa -- Case studies , Leadership -- South Africa -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/171997 , vital:42147
- Description: This study sought to investigate the experiences of leaders involved in a transition from specialist role to leadership role at the Eastern Cape Development Agency, South Africa. A qualitative case study within a constructivist paradigm was adopted. Bridges’ (1991) theory of transition was used in this study to understand and analyse the process of transition in this study. The study used purposive sampling technique, where six leaders were selected and interviewed. The data was analysed through inductive and content analysis techniques. The findings are presented thematically and supported with participants verbatim. The study established that as specialists transition to leadership roles they experience lack of role clarity, stress (role strain), resistance, inadequate support, shock, increased work load (role strain) and role conflict. These experiences influence on their role identity, expertise, peer relationships and financial status. The study also established that for smooth and successful transition, consultation, participation, proper succession planning, and training is vitally important. This was necessary to ease the tension between management, leadership, specialist responsibilities, and resistance from specialists. The study recommends adequate support and preparation in all stages of transition to ensure that the organization benefits from the transition.
- Full Text:
- Date Issued: 2021
- Authors: Mbokoma, Noxolo Patricia
- Date: 2021
- Subjects: Economic development projects -- Managemenat -- South Africa -- Case studies , Organizational change -- South Africa -- Case studies , Organizational behavior -- South Africa -- Case studies , Leadership -- South Africa -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/171997 , vital:42147
- Description: This study sought to investigate the experiences of leaders involved in a transition from specialist role to leadership role at the Eastern Cape Development Agency, South Africa. A qualitative case study within a constructivist paradigm was adopted. Bridges’ (1991) theory of transition was used in this study to understand and analyse the process of transition in this study. The study used purposive sampling technique, where six leaders were selected and interviewed. The data was analysed through inductive and content analysis techniques. The findings are presented thematically and supported with participants verbatim. The study established that as specialists transition to leadership roles they experience lack of role clarity, stress (role strain), resistance, inadequate support, shock, increased work load (role strain) and role conflict. These experiences influence on their role identity, expertise, peer relationships and financial status. The study also established that for smooth and successful transition, consultation, participation, proper succession planning, and training is vitally important. This was necessary to ease the tension between management, leadership, specialist responsibilities, and resistance from specialists. The study recommends adequate support and preparation in all stages of transition to ensure that the organization benefits from the transition.
- Full Text:
- Date Issued: 2021
In marketing, it’s either you have it or you don’t : a study of knowledge and knowers legitimated in the marketing diploma curriculum in South Africa
- Authors: Ncube, Kevin
- Date: 2021
- Subjects: Marketing -- Study and teaching (Higher) -- Curricula , Marketing -- Study and teaching (Higher) -- South Africa , Vocational qualifications -- South Africa , Education, Higher -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172230 , vital:42178 , 10.21504/10962/172230
- Description: This study was undertaken in the South African higher education system in which the differentiation of institutions still reflects racial inequalities from the country’s history of colonial apartheid. As an educator in an institutional type referred to as Universities of Technology, I had become increasingly concerned about who succeeds, how they succeed, who fails, and who drops out. The South Africa education system broadly suffers from low student retention and high drop out with lower success rates mostly affecting Black students. By the end of apartheid in 1994, Black students had been entering Technikons en masse and were the dominant student group in these institutions which changed designation to Universities of Technology in 2005. Technikons offered programmes with a stronger technological and vocational orientation focusing on qualifications directly linked to the job market. They did not offer postgraduate programmes and today, Universities of Technology still produce little research. These institutions also battle with a far lower throughput rate than Traditional Universities and a higher graduate unemployment rate. This has led to a call for better theorised accounts of applied knowledge to replace unhelpful common-sense understandings. There was thus a call in the literature for studies, such as this one, that focused on the nature of knowledge in a diploma curriculum. Furthermore, the field of Marketing is under-researched. The field of Marketing has been characterised as having a weak theoretical foundation and as appropriating knowledge from other fields without growth of the field per se. In Marketing, importance is placed on the possession of a broad spectrum of general knowledge, rather than specialised accounts of the field. The study sought to examine the following research questions: 1) What kind of knowledge is privileged in the Marketing diploma? 2) How does the positioning of actors in the field of Marketing education impact on the choice and structure of knowledge privileged in the curriculum? The study was undertaken mainly through the use of interviews to explore academics’ perspectives on what is valued in the Marketing curriculum. Thirty-one academics from 11 institutions participated in the study. I also analysed course guides and other documentation related to the curriculum. The study analysed the organising of knowledge in the Marketing curriculum. To do this, the study drew on Legitimation Code Theory and in particular the tools of Specialisation and Semantics. These tools allowed the analysis of data to establish the basis on which it is specialised from other fields and the extent to which the field is contextually or conceptually coherent. The data demonstrated that academics who lecture in Marketing entered Marketing education from a diverse range of disciplines. The data also confirmed, in line with the literature, that the field of Marketing draws from multiple disciplines and fields for the purposes of serving the world of work. In Bernsteinian terms the nature of the Marketing curriculum is identified as a ‘region’. However, the data also demonstrated that the field of Marketing serves a heterogenous world of work characterised by constant changes which do not seem to allow a stable development of the field. The field of Marketing was thus portrayed as a region tending towards a generic, raising questions about the reliability of its knowledge base. The nature of generics often leads to an openness which is associated with instability, a weaker autonomy, and an inability to differentiate the field from others with further implications that knowledge in the curriculum is likely to be unsettled. One of the key findings was that while there was significant focus on knowledge, this was not the main basis on which success is achieved. Despite the ample evidence of knowledge in the Marketing curriculum, there was little agreement as to what constituted that knowledge, the actual nature of that knowledge was not settled, broadly agreed upon, nor particularly complex, drawing as it did on ‘everyday’ understandings of the world. The data revealed that there was little evidence that the knowledge was particularly specialised nor that it allowed for cumulative acquisition of ‘powerful knowledge’. Rather, the knowledges in the field of Marketing were characterised by a horizontal knowledge structure consisting of a set of languages acquired separately. The knowledges were based on different and sometimes even contradictory assumptions and thus presented few opportunities to integrate previous theories to build a more powerful knowledge structure. The knowledges tended to be context specific as opposed to being abstract or conceptual. There are social justice implications for fields in which the acquirer is only afforded context specific knowledges and as such has to acquire an endless series of low-level knowledges. They are not given access to powerful knowledge characterised by induction into a system of meaning which enables a more meaningful engagement with the complex world and thinking the not yet thought. In such instances, the education arguably does not provide access to the kind of specialised knowledge which allows for powerful meaning making in the world. The study calls for a strengthening of the epistemic spine of the Marketing diploma to provide access to more abstract, principled knowledge. A major finding was that most of the lecturers’ responses focused on the need for being a particular kind of knower to be successful in Marketing. The kind of person valued in Marketing was portrayed as possessing a particular personality and natural talent which were rarely seen as dependent on the knowledge acquired during the diploma, but rather on the dispositions that students brought. The respondents also mostly raised concerns that most of the students enrolled in Marketing did not to have the requisite ‘Marketing personalities’. Students were expected to be from a particular social class intimated through reference to their backgrounds, the schools they went to, their access to technologies, and the geographical regions they came from. They were expected to bring a particular language competency. Social class and language were arguably also used as coded reference to racial category, and this was more explicitly indicated by some respondents. The dominance of the knower in the data revealed that in Marketing, “you either have it or you don’t” indicating a strong view that Marketers are born with the necessary inherent characteristics of “confidence and people-skills” or belong to the social group that develops them. The implications were that if you do not have it, there is nothing one can do to get . This particular finding raises serious social justice issues on access and success in Marketing. If there is nothing that can be done to develop these characteristics, allowing such people into Marketing is setting them up for failure. On the other hand, denying access based on birth and social grouping raises concerns of the justice in the societies we live in. The study calls for an explicit engagement with the assumptions about the knower’s dispositions. While it was consistently evident that such dispositions were key to the specialisation of the field, the assumption that students either had these dispositions or lacked them is a social injustice and raises a number of unanswerable and painful questions given the racially differentiated success rates. The study concludes by calling for academics to explicitly curriculate for the target dispositions so that students are exposed to the value of these dispositions and given opportunities to engage with them.
- Full Text:
- Date Issued: 2021
- Authors: Ncube, Kevin
- Date: 2021
- Subjects: Marketing -- Study and teaching (Higher) -- Curricula , Marketing -- Study and teaching (Higher) -- South Africa , Vocational qualifications -- South Africa , Education, Higher -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172230 , vital:42178 , 10.21504/10962/172230
- Description: This study was undertaken in the South African higher education system in which the differentiation of institutions still reflects racial inequalities from the country’s history of colonial apartheid. As an educator in an institutional type referred to as Universities of Technology, I had become increasingly concerned about who succeeds, how they succeed, who fails, and who drops out. The South Africa education system broadly suffers from low student retention and high drop out with lower success rates mostly affecting Black students. By the end of apartheid in 1994, Black students had been entering Technikons en masse and were the dominant student group in these institutions which changed designation to Universities of Technology in 2005. Technikons offered programmes with a stronger technological and vocational orientation focusing on qualifications directly linked to the job market. They did not offer postgraduate programmes and today, Universities of Technology still produce little research. These institutions also battle with a far lower throughput rate than Traditional Universities and a higher graduate unemployment rate. This has led to a call for better theorised accounts of applied knowledge to replace unhelpful common-sense understandings. There was thus a call in the literature for studies, such as this one, that focused on the nature of knowledge in a diploma curriculum. Furthermore, the field of Marketing is under-researched. The field of Marketing has been characterised as having a weak theoretical foundation and as appropriating knowledge from other fields without growth of the field per se. In Marketing, importance is placed on the possession of a broad spectrum of general knowledge, rather than specialised accounts of the field. The study sought to examine the following research questions: 1) What kind of knowledge is privileged in the Marketing diploma? 2) How does the positioning of actors in the field of Marketing education impact on the choice and structure of knowledge privileged in the curriculum? The study was undertaken mainly through the use of interviews to explore academics’ perspectives on what is valued in the Marketing curriculum. Thirty-one academics from 11 institutions participated in the study. I also analysed course guides and other documentation related to the curriculum. The study analysed the organising of knowledge in the Marketing curriculum. To do this, the study drew on Legitimation Code Theory and in particular the tools of Specialisation and Semantics. These tools allowed the analysis of data to establish the basis on which it is specialised from other fields and the extent to which the field is contextually or conceptually coherent. The data demonstrated that academics who lecture in Marketing entered Marketing education from a diverse range of disciplines. The data also confirmed, in line with the literature, that the field of Marketing draws from multiple disciplines and fields for the purposes of serving the world of work. In Bernsteinian terms the nature of the Marketing curriculum is identified as a ‘region’. However, the data also demonstrated that the field of Marketing serves a heterogenous world of work characterised by constant changes which do not seem to allow a stable development of the field. The field of Marketing was thus portrayed as a region tending towards a generic, raising questions about the reliability of its knowledge base. The nature of generics often leads to an openness which is associated with instability, a weaker autonomy, and an inability to differentiate the field from others with further implications that knowledge in the curriculum is likely to be unsettled. One of the key findings was that while there was significant focus on knowledge, this was not the main basis on which success is achieved. Despite the ample evidence of knowledge in the Marketing curriculum, there was little agreement as to what constituted that knowledge, the actual nature of that knowledge was not settled, broadly agreed upon, nor particularly complex, drawing as it did on ‘everyday’ understandings of the world. The data revealed that there was little evidence that the knowledge was particularly specialised nor that it allowed for cumulative acquisition of ‘powerful knowledge’. Rather, the knowledges in the field of Marketing were characterised by a horizontal knowledge structure consisting of a set of languages acquired separately. The knowledges were based on different and sometimes even contradictory assumptions and thus presented few opportunities to integrate previous theories to build a more powerful knowledge structure. The knowledges tended to be context specific as opposed to being abstract or conceptual. There are social justice implications for fields in which the acquirer is only afforded context specific knowledges and as such has to acquire an endless series of low-level knowledges. They are not given access to powerful knowledge characterised by induction into a system of meaning which enables a more meaningful engagement with the complex world and thinking the not yet thought. In such instances, the education arguably does not provide access to the kind of specialised knowledge which allows for powerful meaning making in the world. The study calls for a strengthening of the epistemic spine of the Marketing diploma to provide access to more abstract, principled knowledge. A major finding was that most of the lecturers’ responses focused on the need for being a particular kind of knower to be successful in Marketing. The kind of person valued in Marketing was portrayed as possessing a particular personality and natural talent which were rarely seen as dependent on the knowledge acquired during the diploma, but rather on the dispositions that students brought. The respondents also mostly raised concerns that most of the students enrolled in Marketing did not to have the requisite ‘Marketing personalities’. Students were expected to be from a particular social class intimated through reference to their backgrounds, the schools they went to, their access to technologies, and the geographical regions they came from. They were expected to bring a particular language competency. Social class and language were arguably also used as coded reference to racial category, and this was more explicitly indicated by some respondents. The dominance of the knower in the data revealed that in Marketing, “you either have it or you don’t” indicating a strong view that Marketers are born with the necessary inherent characteristics of “confidence and people-skills” or belong to the social group that develops them. The implications were that if you do not have it, there is nothing one can do to get . This particular finding raises serious social justice issues on access and success in Marketing. If there is nothing that can be done to develop these characteristics, allowing such people into Marketing is setting them up for failure. On the other hand, denying access based on birth and social grouping raises concerns of the justice in the societies we live in. The study calls for an explicit engagement with the assumptions about the knower’s dispositions. While it was consistently evident that such dispositions were key to the specialisation of the field, the assumption that students either had these dispositions or lacked them is a social injustice and raises a number of unanswerable and painful questions given the racially differentiated success rates. The study concludes by calling for academics to explicitly curriculate for the target dispositions so that students are exposed to the value of these dispositions and given opportunities to engage with them.
- Full Text:
- Date Issued: 2021
Infant health: a community-based assessment and educational intervention in two rural communities in the Eastern Cape.
- Authors: Kuzeeko, Faith
- Date: 2021
- Subjects: Angus Gillis Foundation (South Africa) , Infants -- Mortality -- South Africa , Infants -- Health and hygiene -- South Africa , Breastfeeding -- South Africa -- Eastern Cape , Infants -- Care -- Equipment and supplies , Infants -- Care -- South Africa -- Eastern Cape -- Case studies , Children -- Mortality -- South Africa , High throughput screening (Drug development)
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/170837 , vital:41964
- Description: South Africa is on track to attaining the 2030 Agenda on reducing under-five deaths to 25 deaths per 1000 live births at its current momentum, however an unacceptable amount of infants are still at risk from preventable illnesses. Malnutrition is the major underlined cause of infant mortality rates in South Africa. Exclusive breastfeeding rates are low nationwide due to low exposure to breastfeeding information, some mothers having other commitments and others having breastfeeding difficulties. Implementation and expansion of simple, cost-effective interventions, such as exclusive breastfeeding for six months to reduce and/or prevent infant mortality rates, remains low in South Africa. The aim of the study was to determine one infant health issue of major concern to participants in two rural villages in the Eastern Cape, namely Glenmore and Ndwayana. The identified infant health issue was used to design an educational intervention in the villages. This was the second phase of this study. A community-based participatory approach was utilized in which the Angus Gillis Foundation, a non-profit organization that works in these communities, was one of the stakeholders. Stock status of WHO priority medicines for infants, semi-structured interviews and focus group discussions were carried out during the baseline study. The intervention phase contained pre-2 intervention semi-structured interviews with ten pregnant women followed by an educational intervention with nine out of the ten; and finally, a post-intervention with seven out of the ten women. A questionnaire was completed by members of the Angus Gillis Foundation to provide feedback on the sustainability of the intervention. Semi-structured interviews revealed that medicines stocked at the clinic parallel those indicated in the WHO priority medicines list for infants. The results from the focus group discussions indicated that mothers do not exclusively breastfeed their infants during the first six months. Pre- and post-intervention results on exclusive breastfeeding illustrated a positive change in participants’ knowledge and intent to breastfeed exclusively for six months. They showed a better understanding of the importance of exclusive breastfeeding and indicated a more focussed intention and confidence to carry out optimal breastfeeding practices. In the questionnaire the members of the Angus Gillis Foundation stated that the intervention is sustainable as it was linked with the existing networks. These include educational programs carried out in the villages by the foundation together with positive health champions, community health workers and women self-help groups; which will be able to build on the present knowledge base. Finally, the study also included the design of a booklet on the identified infant health issue. In conclusion, participants highlighted lack of understanding regarding breastfeeding as an issue of concern during the baseline phase of the study. This community-based educational intervention improved the understanding of breastfeeding among the participants, resulting in a positive change in perception with regards to exclusive breastfeeding practices.
- Full Text:
- Date Issued: 2021
- Authors: Kuzeeko, Faith
- Date: 2021
- Subjects: Angus Gillis Foundation (South Africa) , Infants -- Mortality -- South Africa , Infants -- Health and hygiene -- South Africa , Breastfeeding -- South Africa -- Eastern Cape , Infants -- Care -- Equipment and supplies , Infants -- Care -- South Africa -- Eastern Cape -- Case studies , Children -- Mortality -- South Africa , High throughput screening (Drug development)
- Language: English
- Type: text , Thesis , Masters , MPharm
- Identifier: http://hdl.handle.net/10962/170837 , vital:41964
- Description: South Africa is on track to attaining the 2030 Agenda on reducing under-five deaths to 25 deaths per 1000 live births at its current momentum, however an unacceptable amount of infants are still at risk from preventable illnesses. Malnutrition is the major underlined cause of infant mortality rates in South Africa. Exclusive breastfeeding rates are low nationwide due to low exposure to breastfeeding information, some mothers having other commitments and others having breastfeeding difficulties. Implementation and expansion of simple, cost-effective interventions, such as exclusive breastfeeding for six months to reduce and/or prevent infant mortality rates, remains low in South Africa. The aim of the study was to determine one infant health issue of major concern to participants in two rural villages in the Eastern Cape, namely Glenmore and Ndwayana. The identified infant health issue was used to design an educational intervention in the villages. This was the second phase of this study. A community-based participatory approach was utilized in which the Angus Gillis Foundation, a non-profit organization that works in these communities, was one of the stakeholders. Stock status of WHO priority medicines for infants, semi-structured interviews and focus group discussions were carried out during the baseline study. The intervention phase contained pre-2 intervention semi-structured interviews with ten pregnant women followed by an educational intervention with nine out of the ten; and finally, a post-intervention with seven out of the ten women. A questionnaire was completed by members of the Angus Gillis Foundation to provide feedback on the sustainability of the intervention. Semi-structured interviews revealed that medicines stocked at the clinic parallel those indicated in the WHO priority medicines list for infants. The results from the focus group discussions indicated that mothers do not exclusively breastfeed their infants during the first six months. Pre- and post-intervention results on exclusive breastfeeding illustrated a positive change in participants’ knowledge and intent to breastfeed exclusively for six months. They showed a better understanding of the importance of exclusive breastfeeding and indicated a more focussed intention and confidence to carry out optimal breastfeeding practices. In the questionnaire the members of the Angus Gillis Foundation stated that the intervention is sustainable as it was linked with the existing networks. These include educational programs carried out in the villages by the foundation together with positive health champions, community health workers and women self-help groups; which will be able to build on the present knowledge base. Finally, the study also included the design of a booklet on the identified infant health issue. In conclusion, participants highlighted lack of understanding regarding breastfeeding as an issue of concern during the baseline phase of the study. This community-based educational intervention improved the understanding of breastfeeding among the participants, resulting in a positive change in perception with regards to exclusive breastfeeding practices.
- Full Text:
- Date Issued: 2021
Investigating grade R teacher institutional identity presented in policy and expressed through narrative in a time of transition
- Authors: Long, Roxanne
- Date: 2021
- Subjects: Early childhood education -- South Africa , Early childhood education -- Government policy -- South Africa , Child development -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/171346 , vital:42051 , 10.21504/10962/171346
- Description: This study investigated Grade R (reception year) teacher institutional identity presented in policy and expressed through teacher narratives. The study was conducted in the context of a major national policy transition that involved the physical and contextual shift of Grade R out of the Early Childhood Development sector and into the formal schooling sector. This study highlighted the way in which this shift has resulted in mixed policy messages, which have implications for Grade R teachers’ institutional identities and learning trajectories across their landscapes of practice. The thesis begins by exploring the South African Education context in general as well as the Early Childhood Development context in particular. In order to understand the institutional identities of Grade R teachers as both storied by others (in policy) and by themselves, the study conducted a documentary analysis of policy relating to Grade R teachers and Grade R teacher narrative expressions of their identities. The methodological approach of the study involved a qualitative approach, drawing on grounded theory analytical techniques to closely examine policy documents and teacher generated data gathered through interviews and questionnaires. The study was guided by a sociocultural perspective and drew on three key sociocultural theorists whose work provided complementary perspectives on teacher identity. Sfard and Prusak’s (2005) operationalization of identity as narratives was used to define the unit of analysis for the study (i.e. identities as stories). Gee’s (2000) definition and conceptualization of institutional identity was supplemented with Wenger-Trayner, Fenton-O'Creevy, Hutchinson, Kubiak, and Wenger-Trayner’s (2015) notion of identity as journeying across landscapes of practice. This complementary framing allowed for focused and detailed analysis of policy documents and Grade R teacher identity stories. The study addresses the research gap of an under-representation of identity research in early childhood teacher education and particularly in the South African context. This study is significant as it is the first study of its kind to explore the importance of identity formation for Grade R teachers as newcomers to the formal schooling landscape. Findings from the policy analysis point to mixed messages moving across a spectrum of descriptors from the not yet qualified ‘mothers and ‘caregivers’ to qualified ‘specialised’ educators. These descriptors have implications for the differentiated roles and responsibilities (institutional identity) of Grade R teachers. The findings from teacher identity narratives highlighted tension in the navigation of the policy promoted institutional identities. Teacher narratives pointed to vastly contrasting experiences of teachers with specialised and qualified institutional teacher identities to those with not yet qualified institutional identities. For the former, there were high levels of confidence in their job security and in terms of recognition received from others. For the latter, however, there was vulnerability in terms of the stability of their jobs and remuneration as well as low levels of recognition from others. The study draws on the findings from the analysis to suggest recommendations for Grade R policy, Grade R teacher education (both inservice and pre-service); as well as Grade R professional development initiatives.
- Full Text:
- Date Issued: 2021
- Authors: Long, Roxanne
- Date: 2021
- Subjects: Early childhood education -- South Africa , Early childhood education -- Government policy -- South Africa , Child development -- South Africa
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/171346 , vital:42051 , 10.21504/10962/171346
- Description: This study investigated Grade R (reception year) teacher institutional identity presented in policy and expressed through teacher narratives. The study was conducted in the context of a major national policy transition that involved the physical and contextual shift of Grade R out of the Early Childhood Development sector and into the formal schooling sector. This study highlighted the way in which this shift has resulted in mixed policy messages, which have implications for Grade R teachers’ institutional identities and learning trajectories across their landscapes of practice. The thesis begins by exploring the South African Education context in general as well as the Early Childhood Development context in particular. In order to understand the institutional identities of Grade R teachers as both storied by others (in policy) and by themselves, the study conducted a documentary analysis of policy relating to Grade R teachers and Grade R teacher narrative expressions of their identities. The methodological approach of the study involved a qualitative approach, drawing on grounded theory analytical techniques to closely examine policy documents and teacher generated data gathered through interviews and questionnaires. The study was guided by a sociocultural perspective and drew on three key sociocultural theorists whose work provided complementary perspectives on teacher identity. Sfard and Prusak’s (2005) operationalization of identity as narratives was used to define the unit of analysis for the study (i.e. identities as stories). Gee’s (2000) definition and conceptualization of institutional identity was supplemented with Wenger-Trayner, Fenton-O'Creevy, Hutchinson, Kubiak, and Wenger-Trayner’s (2015) notion of identity as journeying across landscapes of practice. This complementary framing allowed for focused and detailed analysis of policy documents and Grade R teacher identity stories. The study addresses the research gap of an under-representation of identity research in early childhood teacher education and particularly in the South African context. This study is significant as it is the first study of its kind to explore the importance of identity formation for Grade R teachers as newcomers to the formal schooling landscape. Findings from the policy analysis point to mixed messages moving across a spectrum of descriptors from the not yet qualified ‘mothers and ‘caregivers’ to qualified ‘specialised’ educators. These descriptors have implications for the differentiated roles and responsibilities (institutional identity) of Grade R teachers. The findings from teacher identity narratives highlighted tension in the navigation of the policy promoted institutional identities. Teacher narratives pointed to vastly contrasting experiences of teachers with specialised and qualified institutional teacher identities to those with not yet qualified institutional identities. For the former, there were high levels of confidence in their job security and in terms of recognition received from others. For the latter, however, there was vulnerability in terms of the stability of their jobs and remuneration as well as low levels of recognition from others. The study draws on the findings from the analysis to suggest recommendations for Grade R policy, Grade R teacher education (both inservice and pre-service); as well as Grade R professional development initiatives.
- Full Text:
- Date Issued: 2021
Kuntanshi yamikalile (The Future): speculative nonconformity in the works of Zambian visual artists
- Authors: Mulenga,Andrew Mukuka
- Date: 2021
- Subjects: Future in art , Africa -- In art , Art, Zambian , Art, African , Artists -- Zambia , Nyandoro, Gareth
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172203 , vital:42175 , 10.21504/10962/172203
- Description: In recent years, select African visual artists practising on the continent as well as in its diaspora have increasingly been attracted to themes that explore, portray or grapple with Africa’s future. Along with this increasing popularity of the ‘future’ or indeed ‘African futuristic’ themes by visual artists, such themes have also attracted academic consideration among various scholars, resulting primarily in topics described as ‘African Futurism’ or Afrofuturism. These are topics that may be used to disrupt what some scholars – across disciplines and in various contexts – have highlighted as the persistent presumptive notions that portray Africa as a hinterland (Hassan 1999; Sefa Dei, Hall and Goldin Rosenberg 2000; Simbao 2007; Soyinka-Airewele and Edozie 2010; Moyo 2013; Keita, L. 2014; Green 2014; Serpell 2016). This study makes an effort to critique certain aspects of ‘African Art History’ with regard to the representation of Africa, and raises the following question: How can an analysis of artistic portrayals of ‘the future’ portrayed in the works of select contemporary Zambian artists be used to critique the positioning of Africa as ‘backward’, an occurrence at the intersection of a dualistic framing of tradition versus modern. Furthermore, how can this be used to break down this dichotomy in order to challenge lingering perceptions of African belatedness? The study analyses ways in which this belatedness is challenged by the juxtaposition of traditional, contemporary and futuristic elements by discussing a series of topics and debates associated to African cultures and technology that may be deemed disconnected from the contemporary lived experiences of Africans based on the continent. The study acknowledges that there is no singular ‘African Art History’ that one can talk of and there have been various shifts in how it has been perceived. I argue that while currently the African art history that is written in the West does not simplistically position Africa as backward as it may have done in the past, there appear to be moments of a hangover of this perception (Lamp 1999:4). What started out as a largely Western scholarly discourse of African art history occurred in about the 1950s and the journal African Arts started in the 1960s. Even before contemporary African art became a big thing in the 1990s for the largely US- and Europe-based discourses there were many discussions in the US about how the ‘old’ art history tended to freeze time and that this was not appropriate (Drewal 1991 et al). In order to advance the discourse on contemporary African visual arts I present critical analyses of the select works of Zambian artists to develop interpretations of the broader uses of the aforementioned themes. The evidence that supports the core argument of this research is embedded in the images discussed throughout this dissertation. The artists featured in the study span several decades including artists who were active from the 1960s to the 1980s, such as Henry Tayali and Akwila Simpasa, as well as artists who have been practising since the 1980s, such as Chishimba Chansa and William Miko and those that are more current and have been producing work from the early 1990s and 2000s, such as Zenzele Chulu, Milumbe Haimbe, Stary Mwaba, Isaac Kalambata and Roy Jethro Phiri.
- Full Text:
- Date Issued: 2021
- Authors: Mulenga,Andrew Mukuka
- Date: 2021
- Subjects: Future in art , Africa -- In art , Art, Zambian , Art, African , Artists -- Zambia , Nyandoro, Gareth
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172203 , vital:42175 , 10.21504/10962/172203
- Description: In recent years, select African visual artists practising on the continent as well as in its diaspora have increasingly been attracted to themes that explore, portray or grapple with Africa’s future. Along with this increasing popularity of the ‘future’ or indeed ‘African futuristic’ themes by visual artists, such themes have also attracted academic consideration among various scholars, resulting primarily in topics described as ‘African Futurism’ or Afrofuturism. These are topics that may be used to disrupt what some scholars – across disciplines and in various contexts – have highlighted as the persistent presumptive notions that portray Africa as a hinterland (Hassan 1999; Sefa Dei, Hall and Goldin Rosenberg 2000; Simbao 2007; Soyinka-Airewele and Edozie 2010; Moyo 2013; Keita, L. 2014; Green 2014; Serpell 2016). This study makes an effort to critique certain aspects of ‘African Art History’ with regard to the representation of Africa, and raises the following question: How can an analysis of artistic portrayals of ‘the future’ portrayed in the works of select contemporary Zambian artists be used to critique the positioning of Africa as ‘backward’, an occurrence at the intersection of a dualistic framing of tradition versus modern. Furthermore, how can this be used to break down this dichotomy in order to challenge lingering perceptions of African belatedness? The study analyses ways in which this belatedness is challenged by the juxtaposition of traditional, contemporary and futuristic elements by discussing a series of topics and debates associated to African cultures and technology that may be deemed disconnected from the contemporary lived experiences of Africans based on the continent. The study acknowledges that there is no singular ‘African Art History’ that one can talk of and there have been various shifts in how it has been perceived. I argue that while currently the African art history that is written in the West does not simplistically position Africa as backward as it may have done in the past, there appear to be moments of a hangover of this perception (Lamp 1999:4). What started out as a largely Western scholarly discourse of African art history occurred in about the 1950s and the journal African Arts started in the 1960s. Even before contemporary African art became a big thing in the 1990s for the largely US- and Europe-based discourses there were many discussions in the US about how the ‘old’ art history tended to freeze time and that this was not appropriate (Drewal 1991 et al). In order to advance the discourse on contemporary African visual arts I present critical analyses of the select works of Zambian artists to develop interpretations of the broader uses of the aforementioned themes. The evidence that supports the core argument of this research is embedded in the images discussed throughout this dissertation. The artists featured in the study span several decades including artists who were active from the 1960s to the 1980s, such as Henry Tayali and Akwila Simpasa, as well as artists who have been practising since the 1980s, such as Chishimba Chansa and William Miko and those that are more current and have been producing work from the early 1990s and 2000s, such as Zenzele Chulu, Milumbe Haimbe, Stary Mwaba, Isaac Kalambata and Roy Jethro Phiri.
- Full Text:
- Date Issued: 2021
Lipid nanocarriers : a novel approach to delivering ophthalmic clarithromycin
- Authors: Makoni, Pedzisai Anotida
- Date: 2021
- Subjects: Clarithromycin , Nanomedicine , Nanostructures , Antibiotics , Eye -- Diseases -- Treatment , Ocular pharmacology , Ophthalmic drugs , Karatitis -- Chemotherapy
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/171678 , vital:42109 , 10.21504/10962/171678
- Description: The feasibility of incorporating clarithromycin (CLA) into innovative solid lipid nanoparticles (SLN) and nanostructured lipi d carriers (NLC) using hot emulsification ultrasonication (HEUS) was investigated. This approach was investigated in an attempt to address the shortcomings associated with the use of lyophilized parenteral formulations administered via the ocular route suc h as toxic reactions, intolerance and patient discomfort due to frequent insti llation of topical solutions of CLA. In particular, sustained release approaches to delivery may enhance precorneal retention, increase ocular availability and permit dose reduction or use of a longer dosing frequency when treating ocular non - tuberculous m ycobacterial (NTM) keratitis infections. This approach may potentially improve the delivery of CLA to the eye, thereby addressing some or all of the unmet clinical needs described vide infra . Prior to initiating pre - formulation, formulation development a nd optimization studies of CLA - loaded SLN and/or NLC, Design of Experiments (DoE), specifically a Central Composite Design (CCD) was used in conjunction with Response Surface Methodology (RSM) to develop and optimize a suitable method for the quantitative determination of CLA in pharmaceutical formulations and for monitoring CLA release from SLN and/or NLC in vitro . A simple, accurate, precise, sensitive and stability - indicating reversed phase - high performance liquid chromatography (RP - HPLC) method with ele ctrochemical (EC) detection was developed, validated and optimized for the in vitro analysis of CLA loaded SLN and/or NLC formulations. Pre - formulation studies were undertaken to investigate the thermal stability of CLA and bulk lipids to facilitate the s election of lipid excipients for the manufacture of nanocarriers in addition to establishing compatibility of CLA with the excipients. It was established that CLA was thermostable up to a temperature of approximately 300 °C thereby indicating that HEUS cou ld be used for the manufacture of CLA - loaded SLN and/or NLC. Lipid screening revealed that CLA i s, in general, poorly soluble in solid and liquid lipids however a combination of stearic acid (SA) and Transcutol ® HP (THP) exhibited the best dissolution pote ntial for CLA of all lipids tested . Stearic acid appears to exist as polymorphic form B prior to exposure to heat however occurs as the form C polymorph following heating at 85 °C for one hour. The best ratio for the mixture of SA and THP for the manufactu re of CLA - NLC ii was an 80:20 ( w/w ) ratio of SA: THP as the two lipids are miscible in this ratio and exhibited the greatest dissolution potential for CLA. Furthermore, an investigation of binary mixtures of CLA/SA and SA/Transcutol ® HP, in addition to eutect ic mixtures of CLA, SA and Transcutol ® HP, revealed no obvious interaction between CLA and the lipids selected for the production of the nanocarriers. Due to the relatively high solubility of CLA in THP in comparison to SA, NLC are likely to exhibit a hig her loading capacity (LC) and encapsulation efficiency (EE) for CLA than SLN. Consequently the feasibility of incorporating CLA (10% w/w ) into NLC was investigated and evaluation of the production of SLN was not undertaken as the production of these might not result in the manufacture of a delivery technology with a high EE and LC for CLA. Tween ® 20 was used as the surfactant as it is readily available, exhibits little or no cytotoxicity and is relatively cheap. Polyethylene glycol (PEG) was used as a coati ng polymer to impart muco - adhesive properties the formulated CLA - NLC. Response surface methodology (RSM) in conjunction with DoE, specifically a Box - Behnken Design (BBD) used as a screening design was used to identify a formulation composition which would produce a product that would meet the pre - defined target critical quality attributes (CQA) for the nanoparticles viz. particle size (PS) in the nano - range, polydispersity index (PDI) < 0.5, Zeta Potential (ZP) ≥ ± 30 mV, and EE > 80%. The formulation composition identified was subsequently used for the optimization of the manufacturing parameters viz. sonication time and amplitude, using a Central Composite Design (CCD) . The LC and EE, in vitro CLA release, cytotoxicity, osmolarity, pH, degree of crystallinity and lipid modification, elemental analysis and surface morphology of the optimized batch was investigated and mon itored to ensure that CLA - loaded NLC, of the desirable quality, had been produced. On the day of manufacture the mean PS and PDI of the optimized CLA - loaded NLC formulation adjusted to physiological osmolarity (250 – 450 mOsm/kg) was 461.9 ± 40.16 nm and 0. 523 ± 0.104, respectively. The ZP for the optimized NLC generated on the day of manufacture using HPLC grade water as the dispersion medium was - 20.5 ± 4.82 mV. The pH and osmolarity of the optimized CLA - loaded NLC formulation was 7.76 ± 0.01 and 316 ± iii 2 m Osm/Kg, respectively and the EE was 88.62 ± 0.23 %. The optimized NLC exhibited a decreased crystallinity in comparison to the bulk lipid materials. DSC, WAXS and FT - IR revealed that CLA was molecularly dispersed in the nanocarriers. The optimized CLA - load ed NLC exhibited muco - adhesive properties, when tested under stationary conditions using laser doppler anemometry (LDA). The optimized formulation also exhibited sustained release of CLA over 24 hours during in vitro release testing and CLA release was bes t described using the Baker - Lonsdale model . The cumulative % CLA released over 24 hours was 56.13 ± 0.23% and mass balance analysis revealed 41.38 ± 0.02% CLA had been retained in the NLC. In vitro cytotoxicity testing revealed that the optimized CLA - NLC w ere less cytotoxic to HeLa cells when compared to CLA alone and further confirmed that the lipids and excipients used in these studies were of GRAS status . Stability studies revealed that the EE reduced over 28 days by 14.42% and 5.14% when stored at 4 °C and 22 °C , respectively. In addition, the particle size increased from the nm to μm range for samples stored at 22 °C. The findings are a good starting point but require further optimization to ensure prolongation of stability. In addition , the technology requires additional developmental studies and a powder for reconstitution for use as a single - dose considered as single dose packaging may be a solution to the compromised formulation stability observed in these studies. The CLA - NLC produced in these stu dies exhibit sound product attributes which serve as a useful foundation for the novel delivery of antibiotics to the eye. The results suggest that the optimized NLC have the potential to enhance precorneal retention and increase ocular availability of CLA , which in turn may be useful to reduce the required dose and dosing frequency when administering CLA as a reconstituted solution to treat susceptible organisms that infect ocular tissues.
- Full Text:
- Date Issued: 2021
- Authors: Makoni, Pedzisai Anotida
- Date: 2021
- Subjects: Clarithromycin , Nanomedicine , Nanostructures , Antibiotics , Eye -- Diseases -- Treatment , Ocular pharmacology , Ophthalmic drugs , Karatitis -- Chemotherapy
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/171678 , vital:42109 , 10.21504/10962/171678
- Description: The feasibility of incorporating clarithromycin (CLA) into innovative solid lipid nanoparticles (SLN) and nanostructured lipi d carriers (NLC) using hot emulsification ultrasonication (HEUS) was investigated. This approach was investigated in an attempt to address the shortcomings associated with the use of lyophilized parenteral formulations administered via the ocular route suc h as toxic reactions, intolerance and patient discomfort due to frequent insti llation of topical solutions of CLA. In particular, sustained release approaches to delivery may enhance precorneal retention, increase ocular availability and permit dose reduction or use of a longer dosing frequency when treating ocular non - tuberculous m ycobacterial (NTM) keratitis infections. This approach may potentially improve the delivery of CLA to the eye, thereby addressing some or all of the unmet clinical needs described vide infra . Prior to initiating pre - formulation, formulation development a nd optimization studies of CLA - loaded SLN and/or NLC, Design of Experiments (DoE), specifically a Central Composite Design (CCD) was used in conjunction with Response Surface Methodology (RSM) to develop and optimize a suitable method for the quantitative determination of CLA in pharmaceutical formulations and for monitoring CLA release from SLN and/or NLC in vitro . A simple, accurate, precise, sensitive and stability - indicating reversed phase - high performance liquid chromatography (RP - HPLC) method with ele ctrochemical (EC) detection was developed, validated and optimized for the in vitro analysis of CLA loaded SLN and/or NLC formulations. Pre - formulation studies were undertaken to investigate the thermal stability of CLA and bulk lipids to facilitate the s election of lipid excipients for the manufacture of nanocarriers in addition to establishing compatibility of CLA with the excipients. It was established that CLA was thermostable up to a temperature of approximately 300 °C thereby indicating that HEUS cou ld be used for the manufacture of CLA - loaded SLN and/or NLC. Lipid screening revealed that CLA i s, in general, poorly soluble in solid and liquid lipids however a combination of stearic acid (SA) and Transcutol ® HP (THP) exhibited the best dissolution pote ntial for CLA of all lipids tested . Stearic acid appears to exist as polymorphic form B prior to exposure to heat however occurs as the form C polymorph following heating at 85 °C for one hour. The best ratio for the mixture of SA and THP for the manufactu re of CLA - NLC ii was an 80:20 ( w/w ) ratio of SA: THP as the two lipids are miscible in this ratio and exhibited the greatest dissolution potential for CLA. Furthermore, an investigation of binary mixtures of CLA/SA and SA/Transcutol ® HP, in addition to eutect ic mixtures of CLA, SA and Transcutol ® HP, revealed no obvious interaction between CLA and the lipids selected for the production of the nanocarriers. Due to the relatively high solubility of CLA in THP in comparison to SA, NLC are likely to exhibit a hig her loading capacity (LC) and encapsulation efficiency (EE) for CLA than SLN. Consequently the feasibility of incorporating CLA (10% w/w ) into NLC was investigated and evaluation of the production of SLN was not undertaken as the production of these might not result in the manufacture of a delivery technology with a high EE and LC for CLA. Tween ® 20 was used as the surfactant as it is readily available, exhibits little or no cytotoxicity and is relatively cheap. Polyethylene glycol (PEG) was used as a coati ng polymer to impart muco - adhesive properties the formulated CLA - NLC. Response surface methodology (RSM) in conjunction with DoE, specifically a Box - Behnken Design (BBD) used as a screening design was used to identify a formulation composition which would produce a product that would meet the pre - defined target critical quality attributes (CQA) for the nanoparticles viz. particle size (PS) in the nano - range, polydispersity index (PDI) < 0.5, Zeta Potential (ZP) ≥ ± 30 mV, and EE > 80%. The formulation composition identified was subsequently used for the optimization of the manufacturing parameters viz. sonication time and amplitude, using a Central Composite Design (CCD) . The LC and EE, in vitro CLA release, cytotoxicity, osmolarity, pH, degree of crystallinity and lipid modification, elemental analysis and surface morphology of the optimized batch was investigated and mon itored to ensure that CLA - loaded NLC, of the desirable quality, had been produced. On the day of manufacture the mean PS and PDI of the optimized CLA - loaded NLC formulation adjusted to physiological osmolarity (250 – 450 mOsm/kg) was 461.9 ± 40.16 nm and 0. 523 ± 0.104, respectively. The ZP for the optimized NLC generated on the day of manufacture using HPLC grade water as the dispersion medium was - 20.5 ± 4.82 mV. The pH and osmolarity of the optimized CLA - loaded NLC formulation was 7.76 ± 0.01 and 316 ± iii 2 m Osm/Kg, respectively and the EE was 88.62 ± 0.23 %. The optimized NLC exhibited a decreased crystallinity in comparison to the bulk lipid materials. DSC, WAXS and FT - IR revealed that CLA was molecularly dispersed in the nanocarriers. The optimized CLA - load ed NLC exhibited muco - adhesive properties, when tested under stationary conditions using laser doppler anemometry (LDA). The optimized formulation also exhibited sustained release of CLA over 24 hours during in vitro release testing and CLA release was bes t described using the Baker - Lonsdale model . The cumulative % CLA released over 24 hours was 56.13 ± 0.23% and mass balance analysis revealed 41.38 ± 0.02% CLA had been retained in the NLC. In vitro cytotoxicity testing revealed that the optimized CLA - NLC w ere less cytotoxic to HeLa cells when compared to CLA alone and further confirmed that the lipids and excipients used in these studies were of GRAS status . Stability studies revealed that the EE reduced over 28 days by 14.42% and 5.14% when stored at 4 °C and 22 °C , respectively. In addition, the particle size increased from the nm to μm range for samples stored at 22 °C. The findings are a good starting point but require further optimization to ensure prolongation of stability. In addition , the technology requires additional developmental studies and a powder for reconstitution for use as a single - dose considered as single dose packaging may be a solution to the compromised formulation stability observed in these studies. The CLA - NLC produced in these stu dies exhibit sound product attributes which serve as a useful foundation for the novel delivery of antibiotics to the eye. The results suggest that the optimized NLC have the potential to enhance precorneal retention and increase ocular availability of CLA , which in turn may be useful to reduce the required dose and dosing frequency when administering CLA as a reconstituted solution to treat susceptible organisms that infect ocular tissues.
- Full Text:
- Date Issued: 2021
Mapping the transition from a traditional university into an entrepreneurial university
- Authors: Naidoo, Tharusha
- Date: 2021
- Subjects: Rhodes University -- Management , Education, Higher -- South Africa , Education, Higher -- Economic aspects -- South Africa , Academic-industrial cooperation , Entrepreneurship , Business and education -- South Africa , Research -- Economic aspects -- South Africa -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/172214 , vital:42177
- Description: The study aims to map the transition of a traditional university into an entrepreneurial university. The concept of the entrepreneurial university has been established as a game changer in the development and innovation spheres at higher education institutions worldwide. In the year 2002, the South African Higher Education sector embarked on a modelling and redefining journey which gave birth to the National Plan for Higher Education. The Entrepreneurship Development in Higher Education has undertaken work done on the entrepreneurial university which gave rise to the mapping that breeds ground towards policy. This study sought to investigate whether there is a conducive environment at Rhodes University, with an entrepreneurial climate to develop institutional capabilities and build new networks. The research highlights the current direction of Rhodes University and elaborates on the potential for the transition towards an entrepreneurial university. An overview of the entrepreneurial university was provided through an analysis of literature, which dominated in the more developed countries compared to South Africa. The researcher adopted a qualitative research study to capture the direct experiences of the individuals that are in the institution. A questionnaire was designed using the Organisation for Economic Co-operation and Development Guiding Framework and the direct perceptions of academics from the university were documented. The objectives were firstly, to explore elements of leadership and governance that enhance transformation of Higher Education Institution from a traditional university towards an entrepreneurial university. Secondly, to investigate internal resources that enhance Organisational Capacity with specific reference to people and incentives. Lastly, to determine how Teaching and Learning strengthen entrepreneurship development. The interviews revealed that the challenges faced by the institution were closely linked to those recognized by existing literature. What was interesting to note, limited funding and support were regarded as the most significant problems, closely followed by unskilled people and lack of infrastructure. It is suggested that cultivating and nurturing an entrepreneurial culture is of paramount importance together with the creation of a policy framework. Furthermore, the study concluded with practical recommendations proposed to management regarding the three strategic lenses. The research also illustrated that Rhodes University may not be viewed as being entrepreneurial but certainly has pockets of entrepreneurship and innovative activities.
- Full Text:
- Date Issued: 2021
- Authors: Naidoo, Tharusha
- Date: 2021
- Subjects: Rhodes University -- Management , Education, Higher -- South Africa , Education, Higher -- Economic aspects -- South Africa , Academic-industrial cooperation , Entrepreneurship , Business and education -- South Africa , Research -- Economic aspects -- South Africa -- Case studies
- Language: English
- Type: Thesis , Masters , MBA
- Identifier: http://hdl.handle.net/10962/172214 , vital:42177
- Description: The study aims to map the transition of a traditional university into an entrepreneurial university. The concept of the entrepreneurial university has been established as a game changer in the development and innovation spheres at higher education institutions worldwide. In the year 2002, the South African Higher Education sector embarked on a modelling and redefining journey which gave birth to the National Plan for Higher Education. The Entrepreneurship Development in Higher Education has undertaken work done on the entrepreneurial university which gave rise to the mapping that breeds ground towards policy. This study sought to investigate whether there is a conducive environment at Rhodes University, with an entrepreneurial climate to develop institutional capabilities and build new networks. The research highlights the current direction of Rhodes University and elaborates on the potential for the transition towards an entrepreneurial university. An overview of the entrepreneurial university was provided through an analysis of literature, which dominated in the more developed countries compared to South Africa. The researcher adopted a qualitative research study to capture the direct experiences of the individuals that are in the institution. A questionnaire was designed using the Organisation for Economic Co-operation and Development Guiding Framework and the direct perceptions of academics from the university were documented. The objectives were firstly, to explore elements of leadership and governance that enhance transformation of Higher Education Institution from a traditional university towards an entrepreneurial university. Secondly, to investigate internal resources that enhance Organisational Capacity with specific reference to people and incentives. Lastly, to determine how Teaching and Learning strengthen entrepreneurship development. The interviews revealed that the challenges faced by the institution were closely linked to those recognized by existing literature. What was interesting to note, limited funding and support were regarded as the most significant problems, closely followed by unskilled people and lack of infrastructure. It is suggested that cultivating and nurturing an entrepreneurial culture is of paramount importance together with the creation of a policy framework. Furthermore, the study concluded with practical recommendations proposed to management regarding the three strategic lenses. The research also illustrated that Rhodes University may not be viewed as being entrepreneurial but certainly has pockets of entrepreneurship and innovative activities.
- Full Text:
- Date Issued: 2021
News for action: a critical case study of Yes! magazine
- Authors: Hosford-Israel, Carly
- Date: 2021
- Subjects: Yes! (Bainbridge Island, WA) , Magazines -- United States -- History and criticism , Journalistic ethics , Journalism -- Social aspects -- United States , Journalism -- Objectivity , Mass media -- Ownership -- United STates , Publishers and publishing -- United States
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/170822 , vital:41963
- Description: Coming out of more than a century of concern over the commercialization and monopolization of media ownership, this study highlights some areas of opportunity for alternative media in the United States. Holding an ideal of participatory democracy, driven by an educated electorate, the research considers an example of US media action, Ye s ! magazine, from the perspective of alternative media and social movement theories. As alternative media are most generally a response to the mainstream model which acts in the interests of profit rather than public participation in politics, this thesis will cover not only democratic responsibility, but also mainstream media ownership and organization when considering the current manifestation of Ye s ! magazine. Inspired by a frustration with the concentration of mainstream media ownership, and consequently journalistic homogenization, this research explores opportunities for democratic media divergence and contestation. After 18 years of publication, Ye s ! was chosen as an ideal candidate for research due to its sustainability and longevity as one such critical media organization. Through in-depth interviews with Yes! personnel, and ideological analysis of Yes! articles, the following case study research explores the complexities that construct Ye s ! magazine, a corporately independent publication from Bainbridge Island, Washington.
- Full Text:
- Date Issued: 2021
- Authors: Hosford-Israel, Carly
- Date: 2021
- Subjects: Yes! (Bainbridge Island, WA) , Magazines -- United States -- History and criticism , Journalistic ethics , Journalism -- Social aspects -- United States , Journalism -- Objectivity , Mass media -- Ownership -- United STates , Publishers and publishing -- United States
- Language: English
- Type: Thesis , Masters , MA
- Identifier: http://hdl.handle.net/10962/170822 , vital:41963
- Description: Coming out of more than a century of concern over the commercialization and monopolization of media ownership, this study highlights some areas of opportunity for alternative media in the United States. Holding an ideal of participatory democracy, driven by an educated electorate, the research considers an example of US media action, Ye s ! magazine, from the perspective of alternative media and social movement theories. As alternative media are most generally a response to the mainstream model which acts in the interests of profit rather than public participation in politics, this thesis will cover not only democratic responsibility, but also mainstream media ownership and organization when considering the current manifestation of Ye s ! magazine. Inspired by a frustration with the concentration of mainstream media ownership, and consequently journalistic homogenization, this research explores opportunities for democratic media divergence and contestation. After 18 years of publication, Ye s ! was chosen as an ideal candidate for research due to its sustainability and longevity as one such critical media organization. Through in-depth interviews with Yes! personnel, and ideological analysis of Yes! articles, the following case study research explores the complexities that construct Ye s ! magazine, a corporately independent publication from Bainbridge Island, Washington.
- Full Text:
- Date Issued: 2021
Parametrised gains for direction-dependent calibration
- Authors: Russeeaeon, Cyndie
- Date: 2021
- Subjects: Radio astronomy , Radio inferometers , Radio inferometers -- Calibration
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/172400 , vital:42196
- Description: Calibration in radio interferometry describes the process of estimating and correcting for instrumental errors from data. Direction-Dependent (DD) calibration entails correcting for corruptions which vary across the sky. For small field of view observations, DD corruptions can be ignored but for wide fild observations, it is crucial to account for them. Traditional maximum likelihood calibration is not necessarily efficient in low signal-to-noise ratio (SNR) scenarios and this can lead to ovefitting. This can bias continuum subtraction and hence, restrict the spectral line studies. Since DD effects are expected to vary smoothly across the sky, the gains can be parametrised as a smooth function of the sky coordinates. Hence, we implement a solver where the atmosphere is modelled using a time-variant 2-dimensional phase screen with an arbitrary known frequency dependence. We assume arbitrary linear basis functions for the gains over the phase screen. The implemented solver is ptimised using the diagonal approximation of the Hessian as shown in previous studies. We present a few simulations to illustrate the performance of the solver.
- Full Text:
- Date Issued: 2021
- Authors: Russeeaeon, Cyndie
- Date: 2021
- Subjects: Radio astronomy , Radio inferometers , Radio inferometers -- Calibration
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/172400 , vital:42196
- Description: Calibration in radio interferometry describes the process of estimating and correcting for instrumental errors from data. Direction-Dependent (DD) calibration entails correcting for corruptions which vary across the sky. For small field of view observations, DD corruptions can be ignored but for wide fild observations, it is crucial to account for them. Traditional maximum likelihood calibration is not necessarily efficient in low signal-to-noise ratio (SNR) scenarios and this can lead to ovefitting. This can bias continuum subtraction and hence, restrict the spectral line studies. Since DD effects are expected to vary smoothly across the sky, the gains can be parametrised as a smooth function of the sky coordinates. Hence, we implement a solver where the atmosphere is modelled using a time-variant 2-dimensional phase screen with an arbitrary known frequency dependence. We assume arbitrary linear basis functions for the gains over the phase screen. The implemented solver is ptimised using the diagonal approximation of the Hessian as shown in previous studies. We present a few simulations to illustrate the performance of the solver.
- Full Text:
- Date Issued: 2021
Policy and practice of inclusive education for mainstream secondary teachers supporting learners with physical disabilities in the Lower Shire, Malawi
- Authors: De Souza, Ben
- Date: 2021
- Subjects: Children with disabilities -- Education (Secondary) -- Malawi , Children with disabilities -- Education -- Government policy -- Malawi , Children with disabilities -- Legal status, laws, etc. -- Malawi , Inclusive education -- Malawi , Teachers -- Training of -- Malawi , High School teachers -- Malawi -- Attitudes
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/171254 , vital:42038
- Description: The Government of Malawi and its education partners are currently implementing the National Education Policy (2016) and the National Strategy on Inclusive Education (2017-2021). My study explored how mainstream secondary teachers interpret policies and strategies, and transition to the practice of supporting learners with physical disabilities. Previous studies revealed policy-to-practice disparities in the Malawian inclusive secondary education but did not proffer teacher-oriented strategies that can mitigate the disparities and enhance inclusive education. My study argued that effective strategies that could lessen policy-to-practice mismatches and advance inclusive education primarily rest with mainstream teachers, as they mediate policy and practice. This study drew on Clough and Corbett’s disability studies critique and Urie Bronfenbrenner’s bioecological systems perspective to form theoretical and analytical frameworks for understanding the problem and discussing the findings. The study generated primary data from the Lower Shire districts of Chikwawa and Nsanje in Malawi. Thirty-three teachers, randomly selected from four schools, responded to questionnaires. In-depth, face to face interviews were conducted with purposely selected teachers from the same four schools. The study also generated secondary data from a review of policy documents. The findings showed that policy directives are shifting inclusive education from social perspectives to political perspectives, whereby mainstream teachers regard national policies and strategies as political responses to demands for inclusion. The findings further showed that teachers’ practices are moving away from the provision of special needs to the promotion of inclusive needs, whereby inclusive education benefits all learners. The study found that some teachers are resisting inclusive education, and would like learners with physical disabilities to return to special schools, thus controverting policy directives. As a way forward, this study recommended that future policy formulation and implementation in the Malawian mainstream secondary education should consider the bioecological systems approach, whereby policymakers systematically interact with the mainstream secondary teachers to improve their perspectives, competencies and practices on inclusive education.
- Full Text:
- Date Issued: 2021
- Authors: De Souza, Ben
- Date: 2021
- Subjects: Children with disabilities -- Education (Secondary) -- Malawi , Children with disabilities -- Education -- Government policy -- Malawi , Children with disabilities -- Legal status, laws, etc. -- Malawi , Inclusive education -- Malawi , Teachers -- Training of -- Malawi , High School teachers -- Malawi -- Attitudes
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: http://hdl.handle.net/10962/171254 , vital:42038
- Description: The Government of Malawi and its education partners are currently implementing the National Education Policy (2016) and the National Strategy on Inclusive Education (2017-2021). My study explored how mainstream secondary teachers interpret policies and strategies, and transition to the practice of supporting learners with physical disabilities. Previous studies revealed policy-to-practice disparities in the Malawian inclusive secondary education but did not proffer teacher-oriented strategies that can mitigate the disparities and enhance inclusive education. My study argued that effective strategies that could lessen policy-to-practice mismatches and advance inclusive education primarily rest with mainstream teachers, as they mediate policy and practice. This study drew on Clough and Corbett’s disability studies critique and Urie Bronfenbrenner’s bioecological systems perspective to form theoretical and analytical frameworks for understanding the problem and discussing the findings. The study generated primary data from the Lower Shire districts of Chikwawa and Nsanje in Malawi. Thirty-three teachers, randomly selected from four schools, responded to questionnaires. In-depth, face to face interviews were conducted with purposely selected teachers from the same four schools. The study also generated secondary data from a review of policy documents. The findings showed that policy directives are shifting inclusive education from social perspectives to political perspectives, whereby mainstream teachers regard national policies and strategies as political responses to demands for inclusion. The findings further showed that teachers’ practices are moving away from the provision of special needs to the promotion of inclusive needs, whereby inclusive education benefits all learners. The study found that some teachers are resisting inclusive education, and would like learners with physical disabilities to return to special schools, thus controverting policy directives. As a way forward, this study recommended that future policy formulation and implementation in the Malawian mainstream secondary education should consider the bioecological systems approach, whereby policymakers systematically interact with the mainstream secondary teachers to improve their perspectives, competencies and practices on inclusive education.
- Full Text:
- Date Issued: 2021
Prioritising biological control agents for release against Sporobolus pyramidalis and Sporobolus natalensis (Poaceae) in Australia
- Authors: Sutton, Guy Frederick
- Date: 2021
- Subjects: Grasses -- Diseases and pests , Bruchophagus , Wasps , Alien plants -- Biological control -- Australia , Sporobolus -- Biological control -- Africa , Sporobolus -- Biological control -- Australia , Insects as biological pest control agents -- Australia , Insects as biological pest control agents -- Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172445 , vital:42201 , 10.21504/10962/172445
- Description: Sporobolus pyramidalis Beauv. and S. natalensis (Steud.) Th. Dur. and Schinz. (giant rat’s tail grass) (Poaceae), invade rangelands and pastures in eastern Australia, costing the livestock industry approximately AUS$ 60 million per annum in grazing losses. Mechanical and chemical control options are costly and largely ineffective. Biological control is viewed as the most promising control option, however this management strategy has largely been avoided for grasses, due to their perceived lack of suitably host-specific and damaging natural enemies. In this thesis, the prospects for using biological control against S. pyramidalis and S. natalensis in Australia was assessed, in light of these potential challenges. Climate matching models were used to identify high-priority geographic regions within the plants’ native distributions to survey for potential biological control agents. High-priority regions to perform surveys were identified by modelling the climatic suitability for S. pyramidalis and S. natalensis in sub-Saharan Africa (i.e. their potential native ranges’), and climatic compatibility with regions where biological control is intended in Australia. High-priority regions for S. pyramidalis included: (1) coastal East Africa, ranging from north-eastern South Africa to Uganda, including south-eastern DRC, (2) some parts of West Africa, including inland regions of the Ivory Coast and western Nigeria, (3) northern Angola and (4) eastern Madagascar, and for S. natalensis included: (1) eastern South Africa, (2) eastern Zimbabwe, (3) Burundi, (4) central Ethiopia and (5) central Madagascar. Prospective control agents collected from these regions have the highest probability of establishing and proliferating in Australia, if released. In surveys of the insect assemblages on S. pyramidalis and S. natalensis in the climatically-matched region of eastern South Africa fifteen insect herbivores associated with the grasses were identified. Insect feeding guild, geographic distributions, and seasonal abundances suggest that three stem-boring phytophagous wasps, Tetramesa sp. 1, Tetramesa sp. 2 and Bruchophagus sp. 1 (Hymenoptera: Eurytomidae), have potential as control agents. Species accumulation curves indicated that additional surveys in South Africa are unlikely to yield additional potential control agents. Field host-range surveys of 47 non-target grass species in South Africa showed that Tetramesa sp. 1, Tetramesa sp. 2, and Bruchophagus sp. 1, were only recorded from S. pyramidalis and S. natalensis. Integrating field host-range with phylogenetic relationships between plant species indicated that no native Australian Sporobolus species or economic crops and pastures are expected to be attacked by these wasps. All three wasp species are predicted to be suitably host-specific for release in Australia. Three other endophagous herbivores attacked non-target native African Sporobolus species that share a close phylogenetic relationship to native Australian Sporobolus species, and therefore, demonstrate considerable risk of non-target damage. These species should not be considered as potential control agents. Under native-range, open-field conditions, Tetramesa sp. 1 caused an approximately 5-fold greater reduction in plant survival and reproductive output than Tetramesa sp. 2 and Bruchophagus sp. 1. Tetramesa sp. 1 in combination with Tetramesa sp. 2 did not significantly increase the level of damage, while Bruchophagus sp. 1 may decrease the efficiency of Tetramesa sp. 1, if released in combination. Tetramesa 1 is therefore the most promising candidate agent. Prioritising potential agents using predicted efficacy allowed otherwise equally suitable prospective agents to be prioritised in a strategic manner. Prioritising which natural enemies to target as biological control agents is a complex task. Field host range and damage assessments in the native range may provide more realistic data than typical studies performed under artificial conditions in a laboratory or quarantine. Moreover, it could assist practitioners in prioritising the most suitable agent(s) at the earliest stage in the programme as possible. This study demonstrated that grasses are suitable targets for biological control as they can harbour host-specific and damaging natural enemies.
- Full Text:
- Date Issued: 2021
- Authors: Sutton, Guy Frederick
- Date: 2021
- Subjects: Grasses -- Diseases and pests , Bruchophagus , Wasps , Alien plants -- Biological control -- Australia , Sporobolus -- Biological control -- Africa , Sporobolus -- Biological control -- Australia , Insects as biological pest control agents -- Australia , Insects as biological pest control agents -- Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172445 , vital:42201 , 10.21504/10962/172445
- Description: Sporobolus pyramidalis Beauv. and S. natalensis (Steud.) Th. Dur. and Schinz. (giant rat’s tail grass) (Poaceae), invade rangelands and pastures in eastern Australia, costing the livestock industry approximately AUS$ 60 million per annum in grazing losses. Mechanical and chemical control options are costly and largely ineffective. Biological control is viewed as the most promising control option, however this management strategy has largely been avoided for grasses, due to their perceived lack of suitably host-specific and damaging natural enemies. In this thesis, the prospects for using biological control against S. pyramidalis and S. natalensis in Australia was assessed, in light of these potential challenges. Climate matching models were used to identify high-priority geographic regions within the plants’ native distributions to survey for potential biological control agents. High-priority regions to perform surveys were identified by modelling the climatic suitability for S. pyramidalis and S. natalensis in sub-Saharan Africa (i.e. their potential native ranges’), and climatic compatibility with regions where biological control is intended in Australia. High-priority regions for S. pyramidalis included: (1) coastal East Africa, ranging from north-eastern South Africa to Uganda, including south-eastern DRC, (2) some parts of West Africa, including inland regions of the Ivory Coast and western Nigeria, (3) northern Angola and (4) eastern Madagascar, and for S. natalensis included: (1) eastern South Africa, (2) eastern Zimbabwe, (3) Burundi, (4) central Ethiopia and (5) central Madagascar. Prospective control agents collected from these regions have the highest probability of establishing and proliferating in Australia, if released. In surveys of the insect assemblages on S. pyramidalis and S. natalensis in the climatically-matched region of eastern South Africa fifteen insect herbivores associated with the grasses were identified. Insect feeding guild, geographic distributions, and seasonal abundances suggest that three stem-boring phytophagous wasps, Tetramesa sp. 1, Tetramesa sp. 2 and Bruchophagus sp. 1 (Hymenoptera: Eurytomidae), have potential as control agents. Species accumulation curves indicated that additional surveys in South Africa are unlikely to yield additional potential control agents. Field host-range surveys of 47 non-target grass species in South Africa showed that Tetramesa sp. 1, Tetramesa sp. 2, and Bruchophagus sp. 1, were only recorded from S. pyramidalis and S. natalensis. Integrating field host-range with phylogenetic relationships between plant species indicated that no native Australian Sporobolus species or economic crops and pastures are expected to be attacked by these wasps. All three wasp species are predicted to be suitably host-specific for release in Australia. Three other endophagous herbivores attacked non-target native African Sporobolus species that share a close phylogenetic relationship to native Australian Sporobolus species, and therefore, demonstrate considerable risk of non-target damage. These species should not be considered as potential control agents. Under native-range, open-field conditions, Tetramesa sp. 1 caused an approximately 5-fold greater reduction in plant survival and reproductive output than Tetramesa sp. 2 and Bruchophagus sp. 1. Tetramesa sp. 1 in combination with Tetramesa sp. 2 did not significantly increase the level of damage, while Bruchophagus sp. 1 may decrease the efficiency of Tetramesa sp. 1, if released in combination. Tetramesa 1 is therefore the most promising candidate agent. Prioritising potential agents using predicted efficacy allowed otherwise equally suitable prospective agents to be prioritised in a strategic manner. Prioritising which natural enemies to target as biological control agents is a complex task. Field host range and damage assessments in the native range may provide more realistic data than typical studies performed under artificial conditions in a laboratory or quarantine. Moreover, it could assist practitioners in prioritising the most suitable agent(s) at the earliest stage in the programme as possible. This study demonstrated that grasses are suitable targets for biological control as they can harbour host-specific and damaging natural enemies.
- Full Text:
- Date Issued: 2021
Probing the binding sites of novel 2-substituted imidazole-4,5-dicarboxylic acids : Towards new imidazole-based drugs
- Authors: Clark, Candyce Raine
- Date: 2021
- Subjects: Heterocyclic compounds Coordination compounds
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/50848 , vital:42957
- Description: A series of benzimidazole and imidazole-4,5-dicarboxylic acids were prepared using known and adapted protocols. Novel ligands synthesised in this study include 2-tert-butyl-benzimidazole, 2-tert-butyl-imidazole-4,5-dicarboxylic acid, an intermediate in the synthesis of 1,2- bis(2-benzimidazyl)-1,2,-dihydroxyethane and 2-(2-hydroxyphenyl)-benzimidazole with a salicylic acid co-crystallisate. All ligands prepared were reacted with metal salt solutions in order to prepare metal coordination compounds. Complexes with Cu(II), Ag(I), Mn(II), Ni(II) and Cd(II) ions and 2-phenyl-imidazole-4,5-dicarboxylic acid were prepared, as well as Cu(II) and Mn(II) with 2-trifluoro-methyl-imidazole-4,5-dicarboxylic acid and Cu(II) ions with 2-(2- hydroxyphenyl)-benzimidazole. The ligands and complexes were characterised by means of single-crystal X-ray diffraction studies, NMR analysis, UV spectrophotometric analysis and IR spectroscopy. DFT studies were carried out for selected ligands in order to provide theoretical values for comparison. Antimicrobial studies were performed on some of the ligands and complexes and these results show promise for the future development of new imidazole-based drugs.
- Full Text:
- Date Issued: 2021
- Authors: Clark, Candyce Raine
- Date: 2021
- Subjects: Heterocyclic compounds Coordination compounds
- Language: English
- Type: Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10948/50848 , vital:42957
- Description: A series of benzimidazole and imidazole-4,5-dicarboxylic acids were prepared using known and adapted protocols. Novel ligands synthesised in this study include 2-tert-butyl-benzimidazole, 2-tert-butyl-imidazole-4,5-dicarboxylic acid, an intermediate in the synthesis of 1,2- bis(2-benzimidazyl)-1,2,-dihydroxyethane and 2-(2-hydroxyphenyl)-benzimidazole with a salicylic acid co-crystallisate. All ligands prepared were reacted with metal salt solutions in order to prepare metal coordination compounds. Complexes with Cu(II), Ag(I), Mn(II), Ni(II) and Cd(II) ions and 2-phenyl-imidazole-4,5-dicarboxylic acid were prepared, as well as Cu(II) and Mn(II) with 2-trifluoro-methyl-imidazole-4,5-dicarboxylic acid and Cu(II) ions with 2-(2- hydroxyphenyl)-benzimidazole. The ligands and complexes were characterised by means of single-crystal X-ray diffraction studies, NMR analysis, UV spectrophotometric analysis and IR spectroscopy. DFT studies were carried out for selected ligands in order to provide theoretical values for comparison. Antimicrobial studies were performed on some of the ligands and complexes and these results show promise for the future development of new imidazole-based drugs.
- Full Text:
- Date Issued: 2021
Synthesis, spectroscopic and nonlinear optical properties of asymmetric A3B type phthalocyanine complexes
- Authors: Mugeza, Rhulani Donney
- Date: 2021
- Subjects: Spectrum analysis , Mass spectrometry , Phthalocyanines
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/171667 , vital:42108
- Description: This work reports on the synthesis of symmetrical and asymmetrical A 3 B type metal free, cobalt and zinc Phthalocyanines (Pc) .A wide range of spectroscopic techniques such as Uv - visible absorption (UV), magnetic circular dichroism (MCD), mass spectrometry, elemental analysis, IR spectroscopy and time correlated single photo n counting spectroscopy (TCSPC) have been used to study the spectroscopic properties of the phthalocyanine complexes. The Z - scan technique was used to comparatively investigate the nonlinear absorption coefficient ( 휷 ) and the nonlinear refraction index ( 풏 ퟐ ) of the synthesized complexes. The following trend was obtained for the synthesized Pc’s in terms of the 휷 values 7.25 × 10 − 10 ( 4b ) > 3.76 × 10 − 10 ( 4a ) > 3.52 × 10 − 10 ( 4c ) > 2.29 × 10 − 10 ( 3c ) > 1.68 × 10 − 10 ( 3a ) > 1.65 × 10 − 10 ( 3b ) mW - 1 . The 휷 values trend of synthesized Pc complexes show that the asymmetrical A 3 B type metal free, cobalt and zinc Pc complexes ( 4a , 4b and 4c ) have larger 휷 values as compared to the octa - substituted symmetrical metal free, cobalt and zinc Pc complexes ( 3a , 3b and 3c ) which is attributed to the low symmetry of the Pc complexes. The five - level model rate equations were used to determine the two photon absorption, excited state absorption and ground state absorption cross sections of the synthesized complexes. The z inc A 3 B type asymmetrical Pc complexes gave the largest two photon absorption and 휎 푒 / 휎 푔 ratio values. This Pc complex could be used in future work to enhance the nonlinear response further by introducing nanomaterials and converting the Pc complex to a binuclear Pc. This work also reports on the density functional theory (DFT) calculations o f dipolar/octupolar contributions in order to study the first order hyperpolarizability of the synthesized Pc complexes.
- Full Text:
- Date Issued: 2021
- Authors: Mugeza, Rhulani Donney
- Date: 2021
- Subjects: Spectrum analysis , Mass spectrometry , Phthalocyanines
- Language: English
- Type: text , Thesis , Masters , MSc
- Identifier: http://hdl.handle.net/10962/171667 , vital:42108
- Description: This work reports on the synthesis of symmetrical and asymmetrical A 3 B type metal free, cobalt and zinc Phthalocyanines (Pc) .A wide range of spectroscopic techniques such as Uv - visible absorption (UV), magnetic circular dichroism (MCD), mass spectrometry, elemental analysis, IR spectroscopy and time correlated single photo n counting spectroscopy (TCSPC) have been used to study the spectroscopic properties of the phthalocyanine complexes. The Z - scan technique was used to comparatively investigate the nonlinear absorption coefficient ( 휷 ) and the nonlinear refraction index ( 풏 ퟐ ) of the synthesized complexes. The following trend was obtained for the synthesized Pc’s in terms of the 휷 values 7.25 × 10 − 10 ( 4b ) > 3.76 × 10 − 10 ( 4a ) > 3.52 × 10 − 10 ( 4c ) > 2.29 × 10 − 10 ( 3c ) > 1.68 × 10 − 10 ( 3a ) > 1.65 × 10 − 10 ( 3b ) mW - 1 . The 휷 values trend of synthesized Pc complexes show that the asymmetrical A 3 B type metal free, cobalt and zinc Pc complexes ( 4a , 4b and 4c ) have larger 휷 values as compared to the octa - substituted symmetrical metal free, cobalt and zinc Pc complexes ( 3a , 3b and 3c ) which is attributed to the low symmetry of the Pc complexes. The five - level model rate equations were used to determine the two photon absorption, excited state absorption and ground state absorption cross sections of the synthesized complexes. The z inc A 3 B type asymmetrical Pc complexes gave the largest two photon absorption and 휎 푒 / 휎 푔 ratio values. This Pc complex could be used in future work to enhance the nonlinear response further by introducing nanomaterials and converting the Pc complex to a binuclear Pc. This work also reports on the density functional theory (DFT) calculations o f dipolar/octupolar contributions in order to study the first order hyperpolarizability of the synthesized Pc complexes.
- Full Text:
- Date Issued: 2021
The application of human factors and ergonomics (HFE) to community-sport organisations in resource scarce contexts: a case study of grassroots football in Makana, Eastern Cape
- Authors: Bennett, Ryan
- Date: 2021
- Subjects: Makana Local Football Association (South Africa) , Human engineering , Soccer teams -- South Africa -- Makhanda -- Management , Soccer -- Management -- South Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172412 , vital:42198 , 10.21504/10962/172412
- Description: Background: Modern Human Factors and Ergonomics (HFE) focuses on the optimisation of complex socio-technical systems and has been challenged to contribute to broader societal issues. An example is within grassroots football organisations in resource-scarce areas such as Makana, South Africa. Through embedded participatory approaches, the research problem was co-constructed: To investigate the socio-technical system of the Makana Local Football Association (LFA). Method: A useful complex system modelling tool is that of Cognitive Work Analysis (CWA), with its 5 phases used to identify constraints and affordances. Three perspectives were adopted for the application of an adapted (to suit participant characteristics) CWA to the Makana LFA: 1) how work is prescribed by the governing body SAFA, 2) how subject matter experts (SME) disclose its current functioning, and 3) how SMEs imagine it could function. Five SMEs attended 12 three-hour workshops to complete the latter two perspectives. Results: The composite work domain analysis between work as prescribed and work as disclosed identified significant mismatches between how policymakers envision the system and how SMEs report its functioning. Key differences in perspectives included the fundamental purpose of the Makana LFA, while only four of 22 functions operate within the Makana LFA. Participants also identified key affordances for the LFA such as reorientation as a community sports organisation. Discussion: Comparison between perspectives indicated four mismatches. 1) SAFA views the LFA as the foundation of the talent identification and development infrastructure of South African football. SMEs view it as a community centred organisation. 2) A lack of human capacity is evident at the community level of Makana football. 3) Funding and assets are absent at this grassroots level. 4) The LFA relies on other stakeholders, but these relationships are not formalised. Policymakers, therefore, have a lack of knowledge of the contextual challenges faced by LFA administrators. It is recommended that SAFA view the LFA as a community sport organisation, focusing on improving human capacity, increasing funding, and formalising stakeholder networks. Furthermore, conceptual models from CWA provide explicit socio-technical system redesign recommendations. Conclusion: Large mismatches between the organising body SAFA and the actual functioning of the LFA significantly hinder the effective management and running of football at a grassroots level in resource-scarce contexts in South Africa. The perspectives approach to CWA was useful in elucidating the constraints and affordances of the Makana LFA socio-technical system and informing redesign opportunities. Systems HFE methodology is therefore well placed to contribute to broader societal issues within resources scarce contexts such as football in Makana. Furthermore, the philosophical underpinnings of systems based HFE were successful in the development of sustainable participatory research within the South African grassroots football context.
- Full Text:
- Date Issued: 2021
- Authors: Bennett, Ryan
- Date: 2021
- Subjects: Makana Local Football Association (South Africa) , Human engineering , Soccer teams -- South Africa -- Makhanda -- Management , Soccer -- Management -- South Africa
- Language: English
- Type: text , Thesis , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/172412 , vital:42198 , 10.21504/10962/172412
- Description: Background: Modern Human Factors and Ergonomics (HFE) focuses on the optimisation of complex socio-technical systems and has been challenged to contribute to broader societal issues. An example is within grassroots football organisations in resource-scarce areas such as Makana, South Africa. Through embedded participatory approaches, the research problem was co-constructed: To investigate the socio-technical system of the Makana Local Football Association (LFA). Method: A useful complex system modelling tool is that of Cognitive Work Analysis (CWA), with its 5 phases used to identify constraints and affordances. Three perspectives were adopted for the application of an adapted (to suit participant characteristics) CWA to the Makana LFA: 1) how work is prescribed by the governing body SAFA, 2) how subject matter experts (SME) disclose its current functioning, and 3) how SMEs imagine it could function. Five SMEs attended 12 three-hour workshops to complete the latter two perspectives. Results: The composite work domain analysis between work as prescribed and work as disclosed identified significant mismatches between how policymakers envision the system and how SMEs report its functioning. Key differences in perspectives included the fundamental purpose of the Makana LFA, while only four of 22 functions operate within the Makana LFA. Participants also identified key affordances for the LFA such as reorientation as a community sports organisation. Discussion: Comparison between perspectives indicated four mismatches. 1) SAFA views the LFA as the foundation of the talent identification and development infrastructure of South African football. SMEs view it as a community centred organisation. 2) A lack of human capacity is evident at the community level of Makana football. 3) Funding and assets are absent at this grassroots level. 4) The LFA relies on other stakeholders, but these relationships are not formalised. Policymakers, therefore, have a lack of knowledge of the contextual challenges faced by LFA administrators. It is recommended that SAFA view the LFA as a community sport organisation, focusing on improving human capacity, increasing funding, and formalising stakeholder networks. Furthermore, conceptual models from CWA provide explicit socio-technical system redesign recommendations. Conclusion: Large mismatches between the organising body SAFA and the actual functioning of the LFA significantly hinder the effective management and running of football at a grassroots level in resource-scarce contexts in South Africa. The perspectives approach to CWA was useful in elucidating the constraints and affordances of the Makana LFA socio-technical system and informing redesign opportunities. Systems HFE methodology is therefore well placed to contribute to broader societal issues within resources scarce contexts such as football in Makana. Furthermore, the philosophical underpinnings of systems based HFE were successful in the development of sustainable participatory research within the South African grassroots football context.
- Full Text:
- Date Issued: 2021