Economic feasibility of an experimental octopus fishery in South Africa
- Authors: Oosthuizen, Ané
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6760 , http://hdl.handle.net/10962/d1007773
- Description: Octopus vulgaris was identified as a new marine resource to be commercially exploited through an experimental fishery. A recent policy on developing fisheries in South Africa emphasizes the importance of investigating the economic feasibility of a fishery as part of its management framework. The study reported here generated baseline information necessary in the design of the experimental fishery, giving guidelines as to which vessels, fishing gear and markets would be most feasible. The proposed fishery, gear and vessel type, fishing techniques and expected catch rates are described, the results of market research are outlined, and the cost of fishing is estimated. The potential business should consist of small and medium-sized vessels deploying unbaited pots attached to long lines. The longline pot fishery could be economically feasible, provided a 30 percent catch in 6600 pots/month is attained. Only existing, debt-free vessels should be used. The minimum catch per unit effort (CPUE) for various fishing operation scenarios was calculated to determine economic feasibility. This is an estimated minimum CPUE, based on assumptions that cannot be confirmed until the fishery starts. Furthermore, this economic analysis also needs to be assessed by stakeholders with experience of fishery operations , Rhodes Centenary issue of: South African Journal of Science.
- Full Text:
- Date Issued: 2004
- Authors: Oosthuizen, Ané
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6760 , http://hdl.handle.net/10962/d1007773
- Description: Octopus vulgaris was identified as a new marine resource to be commercially exploited through an experimental fishery. A recent policy on developing fisheries in South Africa emphasizes the importance of investigating the economic feasibility of a fishery as part of its management framework. The study reported here generated baseline information necessary in the design of the experimental fishery, giving guidelines as to which vessels, fishing gear and markets would be most feasible. The proposed fishery, gear and vessel type, fishing techniques and expected catch rates are described, the results of market research are outlined, and the cost of fishing is estimated. The potential business should consist of small and medium-sized vessels deploying unbaited pots attached to long lines. The longline pot fishery could be economically feasible, provided a 30 percent catch in 6600 pots/month is attained. Only existing, debt-free vessels should be used. The minimum catch per unit effort (CPUE) for various fishing operation scenarios was calculated to determine economic feasibility. This is an estimated minimum CPUE, based on assumptions that cannot be confirmed until the fishery starts. Furthermore, this economic analysis also needs to be assessed by stakeholders with experience of fishery operations , Rhodes Centenary issue of: South African Journal of Science.
- Full Text:
- Date Issued: 2004
Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases
- Longshaw, Victoria M, Chapple, J Paul, Cheetham, Michael E, Blatch, Gregory L
- Authors: Longshaw, Victoria M , Chapple, J Paul , Cheetham, Michael E , Blatch, Gregory L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6488 , http://hdl.handle.net/10962/d1006271 , https://dx.doi.org/10.1242/jcs.00905
- Description: The co-chaperone murine stress-inducible protein 1 (mSTI1), an Hsp70/Hsp90 organizing protein (Hop) homologue, mediates the assembly of the Hsp70/Hsp90 chaperone heterocomplex. The mSTI1 protein can be phosphorylated in vitro by cell cycle kinases proximal to a putative nuclear localization signal (NLS), which substantiated a predicted casein kinase II (CKII)-cdc2 kinase-NLS (CcN) motif at position 180-239 and suggested that mSTI1 might move between the cytoplasm and the nucleus under certain cell cycle conditions. The mechanism responsible for the cellular localization of mSTI1 was probed using NIH3T3 fibroblasts to investigate the localization of endogenous mSTI1 and enhanced green fluorescent protein (EGFP)-tagged mSTI1 mutants. Localization studies on cell lines stably expressing NLS(mSTI1)-EGFP and EGFP demonstrated that the NLS(mSTI1) was able to promote a nuclear localization of EGFP. The mSTI1 protein was exclusively cytoplasmic in most cells under normal conditions but was present in the nucleus of a subpopulation of cells and accumulated in the nucleus following inhibition of nuclear export (leptomycin B treatment). G1/S-phase arrest (using hydroxyurea) and inhibition of cdc2 kinase (using olomoucine) but not inhibition of casein kinase II (using 5,6-dichlorobenzimidazole riboside), increased the proportion of cells with endogenous mSTI1 nuclear staining. mSTI1-EGFP behaved identically to endogenous mSTI1. The functional importance of key residues was tested using modified mSTI1-EGFP proteins. Inactivation and phosphorylation mimicking of potential phosphorylation sites in mSTI1 altered the nuclear translocation. Mimicking of phosphorylation at the mSTI1 CKII phosphorylation site (S189E) promoted nuclear localization of mSTI1-EGFP. Mimicking phosphorylation at the cdc2 kinase phosphorylation site (T198E) promoted cytoplasmic localization of mSTI1-EGFP at the G1/S-phase transition,whereas removal of this site (T198A) promoted the nuclear localization of mSTI1-EGFP under the same conditions. These data provide the first evidence of nuclear import and export of a major Hsp70/Hsp90 co-chaperone and the regulation of this nuclear-cytoplasmic shuttling by cell cycle status and cell cycle kinases.
- Full Text:
- Date Issued: 2004
Nuclear translocation of the Hsp70/Hsp90 organizing protein mSTI1 is regulated by cell cycle kinases
- Authors: Longshaw, Victoria M , Chapple, J Paul , Cheetham, Michael E , Blatch, Gregory L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6488 , http://hdl.handle.net/10962/d1006271 , https://dx.doi.org/10.1242/jcs.00905
- Description: The co-chaperone murine stress-inducible protein 1 (mSTI1), an Hsp70/Hsp90 organizing protein (Hop) homologue, mediates the assembly of the Hsp70/Hsp90 chaperone heterocomplex. The mSTI1 protein can be phosphorylated in vitro by cell cycle kinases proximal to a putative nuclear localization signal (NLS), which substantiated a predicted casein kinase II (CKII)-cdc2 kinase-NLS (CcN) motif at position 180-239 and suggested that mSTI1 might move between the cytoplasm and the nucleus under certain cell cycle conditions. The mechanism responsible for the cellular localization of mSTI1 was probed using NIH3T3 fibroblasts to investigate the localization of endogenous mSTI1 and enhanced green fluorescent protein (EGFP)-tagged mSTI1 mutants. Localization studies on cell lines stably expressing NLS(mSTI1)-EGFP and EGFP demonstrated that the NLS(mSTI1) was able to promote a nuclear localization of EGFP. The mSTI1 protein was exclusively cytoplasmic in most cells under normal conditions but was present in the nucleus of a subpopulation of cells and accumulated in the nucleus following inhibition of nuclear export (leptomycin B treatment). G1/S-phase arrest (using hydroxyurea) and inhibition of cdc2 kinase (using olomoucine) but not inhibition of casein kinase II (using 5,6-dichlorobenzimidazole riboside), increased the proportion of cells with endogenous mSTI1 nuclear staining. mSTI1-EGFP behaved identically to endogenous mSTI1. The functional importance of key residues was tested using modified mSTI1-EGFP proteins. Inactivation and phosphorylation mimicking of potential phosphorylation sites in mSTI1 altered the nuclear translocation. Mimicking of phosphorylation at the mSTI1 CKII phosphorylation site (S189E) promoted nuclear localization of mSTI1-EGFP. Mimicking phosphorylation at the cdc2 kinase phosphorylation site (T198E) promoted cytoplasmic localization of mSTI1-EGFP at the G1/S-phase transition,whereas removal of this site (T198A) promoted the nuclear localization of mSTI1-EGFP under the same conditions. These data provide the first evidence of nuclear import and export of a major Hsp70/Hsp90 co-chaperone and the regulation of this nuclear-cytoplasmic shuttling by cell cycle status and cell cycle kinases.
- Full Text:
- Date Issued: 2004
Western Alumna inspiring catalyst
- University of Western Ontario
- Authors: University of Western Ontario
- Subjects: Nyokong, Tebello
- Language: English
- Type: Article
- Identifier: vital:7172 , http://hdl.handle.net/10962/d1006078 , Nyokong, Tebello
- Description: University of Western Ontario President's Report 2004
- Full Text:
- Authors: University of Western Ontario
- Subjects: Nyokong, Tebello
- Language: English
- Type: Article
- Identifier: vital:7172 , http://hdl.handle.net/10962/d1006078 , Nyokong, Tebello
- Description: University of Western Ontario President's Report 2004
- Full Text:
Living with crime: Does crime affect victims' perceived quality of life?
- Authors: Moller, Valerie
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:21018 , http://hdl.handle.net/10962/6027 , http://dx.doi.org/10.17159/2413-3108/2004/v0i9a1032
- Description: Crime is thought to be a major concern that shapes the everyday lives of South Africans. But what impact does living with high levels of crime have on the mindset of ordinary citizens? A recent household crime victimisation study conducted in the Nelson Mandela Metropolitan Municipality provides tentative answers to this question.
- Full Text:
- Date Issued: 2004
- Authors: Moller, Valerie
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:21018 , http://hdl.handle.net/10962/6027 , http://dx.doi.org/10.17159/2413-3108/2004/v0i9a1032
- Description: Crime is thought to be a major concern that shapes the everyday lives of South Africans. But what impact does living with high levels of crime have on the mindset of ordinary citizens? A recent household crime victimisation study conducted in the Nelson Mandela Metropolitan Municipality provides tentative answers to this question.
- Full Text:
- Date Issued: 2004
Vice-Chancellor's Annual Review 2004
- Language: English
- Type: Article
- Identifier: vital:7169 , http://hdl.handle.net/10962/d1006071
- Description: The highlight of 2004 was the award of both the Vice-Chancellor's Senior Research Award and the SABC2 Shoprite-Checkers Woman of the Year Award (Science and Technology) to Professor Tebello Nyokong, whose research on the development of photosensitisers for photodynamic cancer therapy has received considerable attention.
- Full Text:
- Language: English
- Type: Article
- Identifier: vital:7169 , http://hdl.handle.net/10962/d1006071
- Description: The highlight of 2004 was the award of both the Vice-Chancellor's Senior Research Award and the SABC2 Shoprite-Checkers Woman of the Year Award (Science and Technology) to Professor Tebello Nyokong, whose research on the development of photosensitisers for photodynamic cancer therapy has received considerable attention.
- Full Text:
Evolution of Labeo victorianus predates the Pleistocene desiccation of Lake Victoria: evidence from mitochondrial DNA sequence variation
- Rutaisire, Justus, Booth, Anthony J, Masembe, C, Nyakaana, S, Muwanika, V B
- Authors: Rutaisire, Justus , Booth, Anthony J , Masembe, C , Nyakaana, S , Muwanika, V B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6762 , http://hdl.handle.net/10962/d1007924
- Description: Geological data show that Lake Victoria dried out some 15 000 years ago. These data suggest that the entire faunal diversity within the lake has evolved since this time. However, mitochondrial DNA sequence diversity in the endemic cyprinid fish, Labeo victorianus, was high (24 haplotypes in 38 individuals; percentage sequence divergence of 0.74%), suggesting that the evolution of this species predates this Late Pleistocene climatological event. This finding is consistent with what has been reported earlier for cichlid fishes in the lake.
- Full Text:
- Date Issued: 2004
- Authors: Rutaisire, Justus , Booth, Anthony J , Masembe, C , Nyakaana, S , Muwanika, V B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6762 , http://hdl.handle.net/10962/d1007924
- Description: Geological data show that Lake Victoria dried out some 15 000 years ago. These data suggest that the entire faunal diversity within the lake has evolved since this time. However, mitochondrial DNA sequence diversity in the endemic cyprinid fish, Labeo victorianus, was high (24 haplotypes in 38 individuals; percentage sequence divergence of 0.74%), suggesting that the evolution of this species predates this Late Pleistocene climatological event. This finding is consistent with what has been reported earlier for cichlid fishes in the lake.
- Full Text:
- Date Issued: 2004
The general election in Lesotho, May 2002: adapting to MMP
- Fox, Roddy C, Southall, Roger J
- Authors: Fox, Roddy C , Southall, Roger J
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6680 , http://hdl.handle.net/10962/d1006673
- Description: Voters in the small southern African kingdom of Lesotho went to the polls on 25 May 2002, in the third general election since the country returned to democracy following a long period of civilian dictatorship (1970–1986) and military rule (1986–1993). Voting in all Lesotho’s general elections has usually gone smoothly, yet in every case prior to 2002 the results have been challenged, with varying severity, by the losing parties (Weisfelder, 1999). This occurred most notably in 1970, when the ruling Basotho National Party (BNP) lost the election but overrode the result, and subsequently in 1998, when the BNP—then in opposition—was at the core of an alliance of electoral losers; in the months that followed, and with the quiet support of the security forces, the capital was so paralysed that the government called for external assistance to restore order. The result was military intervention by South Africa and Botswana (who acted on behalf of the Southern African Development Community, SADC), the restoration of power to the Lesotho Congress for Democracy (LCD), and an extended period when, backed by South African muscle, long overdue reforms of the military and police were implemented. These reforms were matched by negotiations between the parties about adopting a new electoral system. The outcome moved Lesotho away from the first-past-the-post system inherited from Britain at independence (which in 1993 and 1998 had resulted in highly imbalanced results favouring the winning party) towards a Mixed Member Proportional (MMP) system. Lesotho became the first country in Africa to adopt MMP at a time when discussion of electoral system change was becoming widespread throughout the continent. The issue in Lesotho in 2002 was not merely whether MMP would provide greater electoral legitimacy and political stability; subsequent events have provided a resounding ‘Yes’ (Elklit, 2002 and Southall, 2003). But there were questions about the practicality of the new system and whether voters would understand it. Was it possible to explain a new voting system to an electorate in one of Africa’s poorest countries? The main focus of this Note is to demonstrate that voters can adapt to electoral system change. Thus, it throws doubt on arguments that electoral reforms in Africa should be avoided due to a lack of sophistication among poor and largely uneducated voters. Electors in Lesotho appeared to have no great difficulty in understanding the broad principles of the new electoral system, even if the detailed mechanics of ‘mixed’ voting systems may have been beyond them.
- Full Text:
- Date Issued: 2004
- Authors: Fox, Roddy C , Southall, Roger J
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6680 , http://hdl.handle.net/10962/d1006673
- Description: Voters in the small southern African kingdom of Lesotho went to the polls on 25 May 2002, in the third general election since the country returned to democracy following a long period of civilian dictatorship (1970–1986) and military rule (1986–1993). Voting in all Lesotho’s general elections has usually gone smoothly, yet in every case prior to 2002 the results have been challenged, with varying severity, by the losing parties (Weisfelder, 1999). This occurred most notably in 1970, when the ruling Basotho National Party (BNP) lost the election but overrode the result, and subsequently in 1998, when the BNP—then in opposition—was at the core of an alliance of electoral losers; in the months that followed, and with the quiet support of the security forces, the capital was so paralysed that the government called for external assistance to restore order. The result was military intervention by South Africa and Botswana (who acted on behalf of the Southern African Development Community, SADC), the restoration of power to the Lesotho Congress for Democracy (LCD), and an extended period when, backed by South African muscle, long overdue reforms of the military and police were implemented. These reforms were matched by negotiations between the parties about adopting a new electoral system. The outcome moved Lesotho away from the first-past-the-post system inherited from Britain at independence (which in 1993 and 1998 had resulted in highly imbalanced results favouring the winning party) towards a Mixed Member Proportional (MMP) system. Lesotho became the first country in Africa to adopt MMP at a time when discussion of electoral system change was becoming widespread throughout the continent. The issue in Lesotho in 2002 was not merely whether MMP would provide greater electoral legitimacy and political stability; subsequent events have provided a resounding ‘Yes’ (Elklit, 2002 and Southall, 2003). But there were questions about the practicality of the new system and whether voters would understand it. Was it possible to explain a new voting system to an electorate in one of Africa’s poorest countries? The main focus of this Note is to demonstrate that voters can adapt to electoral system change. Thus, it throws doubt on arguments that electoral reforms in Africa should be avoided due to a lack of sophistication among poor and largely uneducated voters. Electors in Lesotho appeared to have no great difficulty in understanding the broad principles of the new electoral system, even if the detailed mechanics of ‘mixed’ voting systems may have been beyond them.
- Full Text:
- Date Issued: 2004
Reduction in transport in wheat (Triticum aestivum) is caused by sustained phloem feeding by the Russian wheat aphid (Diuraphis noxia)
- Botha, Christiaan E J, Matsiliza, Babalwa
- Authors: Botha, Christiaan E J , Matsiliza, Babalwa
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6498 , http://hdl.handle.net/10962/d1004498
- Description: The Russian wheat aphid (Diuraphis noxia) feeds preferentially from the phloem of longitudinal veins of nonresistant wheat leaves. The xenobiotic, 5,6-CFDA was applied to exposed leaf blade mesophyll cells in control and aphid-infested plants. In control plants, the fluorophore moved approximately 5–6cm from the point of application of 5,6-CFDA within 3h of application. The fluorochrome was transported in the sieve tube companion cell complex, including those in the numerous interconnecting transverse veins. Leaf blades on which the Russian wheat aphid had been feeding demonstrated a marked decrease in 5,6-CF transport. Aphids feeding on the leaves formed local sinks and redirected the fluorophore (and presumably associated assimilate) to the aphids’ gut, with little longitudinal translocation of 5,6-CF below inserted stylets or aphid feeding areas. Aniline blue staining revealed massive deposits of wound and reaction callose caused by the aphids, with callose associated with the sieve plates, pore-plasmodesma between the companion cells and their associated sieve tubes, as well as with plasmodesmal aggregates in parenchymatous elements within the vascular bundles. Leaves that had been colonised by aphids but from which the aphids were removed, showed extensive wound callose deposits, which persisted for up to 48h after removal of aphid colonies, suggesting that the damage caused by aphid feeding is a long-term, non-transient event in non-resistant plants.
- Full Text:
- Date Issued: 2004
- Authors: Botha, Christiaan E J , Matsiliza, Babalwa
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6498 , http://hdl.handle.net/10962/d1004498
- Description: The Russian wheat aphid (Diuraphis noxia) feeds preferentially from the phloem of longitudinal veins of nonresistant wheat leaves. The xenobiotic, 5,6-CFDA was applied to exposed leaf blade mesophyll cells in control and aphid-infested plants. In control plants, the fluorophore moved approximately 5–6cm from the point of application of 5,6-CFDA within 3h of application. The fluorochrome was transported in the sieve tube companion cell complex, including those in the numerous interconnecting transverse veins. Leaf blades on which the Russian wheat aphid had been feeding demonstrated a marked decrease in 5,6-CF transport. Aphids feeding on the leaves formed local sinks and redirected the fluorophore (and presumably associated assimilate) to the aphids’ gut, with little longitudinal translocation of 5,6-CF below inserted stylets or aphid feeding areas. Aniline blue staining revealed massive deposits of wound and reaction callose caused by the aphids, with callose associated with the sieve plates, pore-plasmodesma between the companion cells and their associated sieve tubes, as well as with plasmodesmal aggregates in parenchymatous elements within the vascular bundles. Leaves that had been colonised by aphids but from which the aphids were removed, showed extensive wound callose deposits, which persisted for up to 48h after removal of aphid colonies, suggesting that the damage caused by aphid feeding is a long-term, non-transient event in non-resistant plants.
- Full Text:
- Date Issued: 2004
Developing evidence-based practice: the role of case-based research
- Edwards, D J A, Dattilio, F M, Bromley, D B
- Authors: Edwards, D J A , Dattilio, F M , Bromley, D B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6243 , http://hdl.handle.net/10962/d1007856
- Description: How can practitioners engage in evidence-based practice when the evidence for effectiveness of psychological treatments comes from randomized controlled trials using patient populations different from those encountered in everyday settings and treatment manuals that seem oversimplified and inflexible? The authors argue that important evidence about best practice comes from case-based research, which builds knowledge in a clinically useful manner and complements what is achieved by multivariate research methods. A multidimensional model of the research process is provided that includes clinical practice and case-based research as significant contributors. The authors summarize the principles of case-based research and provide examples of recent technical advances. Finally, the authors suggest ways in which practitioners can apply the case-based approach in researching and publishing their own cases, perhaps in collaboration with university-based researchers.
- Full Text:
- Date Issued: 2004
- Authors: Edwards, D J A , Dattilio, F M , Bromley, D B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6243 , http://hdl.handle.net/10962/d1007856
- Description: How can practitioners engage in evidence-based practice when the evidence for effectiveness of psychological treatments comes from randomized controlled trials using patient populations different from those encountered in everyday settings and treatment manuals that seem oversimplified and inflexible? The authors argue that important evidence about best practice comes from case-based research, which builds knowledge in a clinically useful manner and complements what is achieved by multivariate research methods. A multidimensional model of the research process is provided that includes clinical practice and case-based research as significant contributors. The authors summarize the principles of case-based research and provide examples of recent technical advances. Finally, the authors suggest ways in which practitioners can apply the case-based approach in researching and publishing their own cases, perhaps in collaboration with university-based researchers.
- Full Text:
- Date Issued: 2004
Three decades of hydrological modelling research in South Africa
- Authors: Hughes, Denis A
- Date: 2004
- Language: English
- Type: text , Article
- Identifier: vital:7072 , http://hdl.handle.net/10962/d1009526
- Description: This paper presents a review of the research undertaken in the field of hydrological modelling over roughly the last three decades, concentrating primarily on South African work in an international context. The focus is on deterministic, rainfall-runoff models and addresses issues related to model design as well as to the application of models in practice. I provide a brief description of what hydrological models are and what they are used for and discuss also the following issues: • Developments in understanding hydrological process and the extent to which these have filtered down into models. • Model calibration and parameter estimation. • Trends in data availability and how these have affected model development. • Trends in computer technology and their impacts on model development. I suggest that there have been substantial developments in the science and practice of hydrological modelling, but that there remain many problems that need to be addressed to improve the ability of models to contribute to the solution of problems of water resource management. Southern African scientists have contributed to the body of knowledge on hydrological modelling, despite the limited resources available compared to resources elsewhere. Internationally, the focus has not always been on the practical issues of model application and has commonly tended towards the more theoretical and mathematical issues of model calibration. This is not a trend that has found much favour in southern Africa (particularly amongst research funding agencies), where there are many problems of water resource management that have the potential to be resolved with existing models, applied in an appropriate way. The paper concludes by suggesting that further research needs to focus on the integration of the best in international developments with the tried and tested models that have been developed locally. The context of this research should be the search for more reliable estimations of water resource availability.
- Full Text:
- Date Issued: 2004
- Authors: Hughes, Denis A
- Date: 2004
- Language: English
- Type: text , Article
- Identifier: vital:7072 , http://hdl.handle.net/10962/d1009526
- Description: This paper presents a review of the research undertaken in the field of hydrological modelling over roughly the last three decades, concentrating primarily on South African work in an international context. The focus is on deterministic, rainfall-runoff models and addresses issues related to model design as well as to the application of models in practice. I provide a brief description of what hydrological models are and what they are used for and discuss also the following issues: • Developments in understanding hydrological process and the extent to which these have filtered down into models. • Model calibration and parameter estimation. • Trends in data availability and how these have affected model development. • Trends in computer technology and their impacts on model development. I suggest that there have been substantial developments in the science and practice of hydrological modelling, but that there remain many problems that need to be addressed to improve the ability of models to contribute to the solution of problems of water resource management. Southern African scientists have contributed to the body of knowledge on hydrological modelling, despite the limited resources available compared to resources elsewhere. Internationally, the focus has not always been on the practical issues of model application and has commonly tended towards the more theoretical and mathematical issues of model calibration. This is not a trend that has found much favour in southern Africa (particularly amongst research funding agencies), where there are many problems of water resource management that have the potential to be resolved with existing models, applied in an appropriate way. The paper concludes by suggesting that further research needs to focus on the integration of the best in international developments with the tried and tested models that have been developed locally. The context of this research should be the search for more reliable estimations of water resource availability.
- Full Text:
- Date Issued: 2004
Constructing a cardinal measure of democratic development in a transition polity: the Nigerian example
- Dinneya, Godson E, Tsegaye, Asrat
- Authors: Dinneya, Godson E , Tsegaye, Asrat
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6076 , http://hdl.handle.net/10962/d1003837
- Description: Existing measures of the level of democracy present in a given state treat democracy as a product and therefore place undue emphasis on actual freedoms enjoyed by the citizens of the country. In transition polities where the actual levels of freedom are low despite continuing efforts to democratize, democracy should be seen as a process rather than a product. A measure that dilutes the end product to capture today's struggles against undemocratic structures and policies does so in order to recognize the foundations these inputs lay for future democratic development. Nigeria exemplifies the many polities in transition on the African continent. This essay looks at the major political events that typify the processes of power change, quality of governance, political environment and democratic dividends, and uses them to construct democratization indices to determine the pattern and level of democratization in Nigeria since political independence. This exercise sets the stage for assessing the impacts of various dimensions of democratization on the performance of the Nigerian economy.
- Full Text:
- Date Issued: 2004
- Authors: Dinneya, Godson E , Tsegaye, Asrat
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6076 , http://hdl.handle.net/10962/d1003837
- Description: Existing measures of the level of democracy present in a given state treat democracy as a product and therefore place undue emphasis on actual freedoms enjoyed by the citizens of the country. In transition polities where the actual levels of freedom are low despite continuing efforts to democratize, democracy should be seen as a process rather than a product. A measure that dilutes the end product to capture today's struggles against undemocratic structures and policies does so in order to recognize the foundations these inputs lay for future democratic development. Nigeria exemplifies the many polities in transition on the African continent. This essay looks at the major political events that typify the processes of power change, quality of governance, political environment and democratic dividends, and uses them to construct democratization indices to determine the pattern and level of democratization in Nigeria since political independence. This exercise sets the stage for assessing the impacts of various dimensions of democratization on the performance of the Nigerian economy.
- Full Text:
- Date Issued: 2004
Rare earth element geochemistry of the Insizwa lobe of the Mount Ayliff Complex, Eastern Cape, South Africa
- Authors: Marsh, Julian S
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6736 , http://hdl.handle.net/10962/d1007548
- Description: New rare earth element (REE) data from all lithologies of the Insizwa lobe, Mount Ayliff Complex, are presented. On the basis of size and type of Eu anomaly, the geochemical subdivision of the complex as previously described is sustained and, additionally, the Top Gabbronorite of the Central Zone is shown to have formed from a magma that was compositionally distinct from other Central Zone magmas. The Basal Zone crystallized from magmas with large negative Eu anomalies probably acquired through crustal contamination. Previously recognized compositional heterogeneity in the contact rocks is also a feature of the REE. Overall, the Insizwa magmas had higher La/Sm ratios and, to a lesser extent, higher Gd/Yb ratios than Karoo basalts and appear to have no representatives in the basalt lava sequence of Lesotho.
- Full Text:
- Date Issued: 2004
- Authors: Marsh, Julian S
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6736 , http://hdl.handle.net/10962/d1007548
- Description: New rare earth element (REE) data from all lithologies of the Insizwa lobe, Mount Ayliff Complex, are presented. On the basis of size and type of Eu anomaly, the geochemical subdivision of the complex as previously described is sustained and, additionally, the Top Gabbronorite of the Central Zone is shown to have formed from a magma that was compositionally distinct from other Central Zone magmas. The Basal Zone crystallized from magmas with large negative Eu anomalies probably acquired through crustal contamination. Previously recognized compositional heterogeneity in the contact rocks is also a feature of the REE. Overall, the Insizwa magmas had higher La/Sm ratios and, to a lesser extent, higher Gd/Yb ratios than Karoo basalts and appear to have no representatives in the basalt lava sequence of Lesotho.
- Full Text:
- Date Issued: 2004
Design and evaluation of a new pharmaceutical pictogram sequence to convey medicine usage
- Mansoor, Leila E, Dowse, Roslind
- Authors: Mansoor, Leila E , Dowse, Roslind
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6402 , http://hdl.handle.net/10962/d1006338
- Description: Pictorials may be used to augment textual instructions in the depiction of safety and warning information on medicines. The objective of this study was to design, develop and evaluate a simple and culturally appropriate pictogram sequence for using nystatin suspension, and to assess its understandability in low-literate Xhosa participants. A new pharmaceutical pictogram sequence was designed through focus group discussions and evaluated in a 2-phase process. The results of Phase 1 (30 participants) identified various problems associated with the new pictogram sequence. It was modified accordingly and re-evaluated in Phase 2 with 20 participants. All participants belonged to the Xhosa group, had between 0 and 7 years of formal schooling and had English as their second language. Acceptance of the new pictogram sequence was based on international standards (ANSI and ISO criterion) for evaluating the comprehensibility of pictograms. In Phase 1, the new pictogram sequence was correctly interpreted by 66.7% of the participants and this complied with the ISO criterion of 67% correct. In Phase 2, 95% of the participants were able to correctly interpret the new pictogram sequence. This result complied with the ANSI criterion of 85% correct, therefore, this new pictogram sequence was considered to be acceptable. This study has illustrated the success of using a consultative approach in the design of new pictograms.
- Full Text:
- Date Issued: 2004
- Authors: Mansoor, Leila E , Dowse, Roslind
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6402 , http://hdl.handle.net/10962/d1006338
- Description: Pictorials may be used to augment textual instructions in the depiction of safety and warning information on medicines. The objective of this study was to design, develop and evaluate a simple and culturally appropriate pictogram sequence for using nystatin suspension, and to assess its understandability in low-literate Xhosa participants. A new pharmaceutical pictogram sequence was designed through focus group discussions and evaluated in a 2-phase process. The results of Phase 1 (30 participants) identified various problems associated with the new pictogram sequence. It was modified accordingly and re-evaluated in Phase 2 with 20 participants. All participants belonged to the Xhosa group, had between 0 and 7 years of formal schooling and had English as their second language. Acceptance of the new pictogram sequence was based on international standards (ANSI and ISO criterion) for evaluating the comprehensibility of pictograms. In Phase 1, the new pictogram sequence was correctly interpreted by 66.7% of the participants and this complied with the ISO criterion of 67% correct. In Phase 2, 95% of the participants were able to correctly interpret the new pictogram sequence. This result complied with the ANSI criterion of 85% correct, therefore, this new pictogram sequence was considered to be acceptable. This study has illustrated the success of using a consultative approach in the design of new pictograms.
- Full Text:
- Date Issued: 2004
The bells of Jamestown, South Atlantic Ocean
- Authors: Lewis, Colin A
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6177 , http://hdl.handle.net/10962/d1012370 , http://www.ringingworld.co.uk
- Description: Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa.
- Full Text:
- Date Issued: 2004
- Authors: Lewis, Colin A
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6177 , http://hdl.handle.net/10962/d1012370 , http://www.ringingworld.co.uk
- Description: Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa.
- Full Text:
- Date Issued: 2004
Science after a century at Rhodes University
- Authors: Woods, D R
- Date: 2004
- Language: English
- Type: Article , text
- Identifier: vital:7123 , http://hdl.handle.net/10962/d1006584
- Description: Rhodes Centenary issue , The small University of Rhodes (6142 students), in the rural city of Grahamstown, was established in 1904 as a result of a £50 000 grant from the Rhodes Trust in Oxford. It grew out of St Andrew’s College, which provided the first four professors and 41 students. The first paper from Rhodes in the South African Journal of Science (then called the Report of the South African Association for the Advancement of Science) was by Selmar Schonland, one of the university’s founding fathers. Entitled: ‘Biological and ethnological observations on a trip to the N.E. Kalahari’, it appeared in 1904. The following pages provide a glimpse into the growth and achievements of various departments in the faculties of Science and Pharmacy and associated institutes a century after the university was born.
- Full Text:
- Date Issued: 2004
- Authors: Woods, D R
- Date: 2004
- Language: English
- Type: Article , text
- Identifier: vital:7123 , http://hdl.handle.net/10962/d1006584
- Description: Rhodes Centenary issue , The small University of Rhodes (6142 students), in the rural city of Grahamstown, was established in 1904 as a result of a £50 000 grant from the Rhodes Trust in Oxford. It grew out of St Andrew’s College, which provided the first four professors and 41 students. The first paper from Rhodes in the South African Journal of Science (then called the Report of the South African Association for the Advancement of Science) was by Selmar Schonland, one of the university’s founding fathers. Entitled: ‘Biological and ethnological observations on a trip to the N.E. Kalahari’, it appeared in 1904. The following pages provide a glimpse into the growth and achievements of various departments in the faculties of Science and Pharmacy and associated institutes a century after the university was born.
- Full Text:
- Date Issued: 2004
A capillary zone electrophoresis (CZE) method for the determination of cyclizine hydrochloride in tablets and suppositories
- Mohammadi, I, Kanfer, Isadore, Walker, Roderick B
- Authors: Mohammadi, I , Kanfer, Isadore , Walker, Roderick B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6406 , http://hdl.handle.net/10962/d1006479
- Description: Current compendial methods of assay for the analysis of cyclizine tablets involve the use of UV spectrophotometry. Since this is a non-selective technique its application to more complex dosage forms, such as suppositories, is unlikely to be appropriate. There is therefore a need for the development of a highly specific quantitative analytical method, such as high performance liquid chromatography (HPLC) or capillary electrophoresis (CE). The latter technique was chosen in view of some specific advantages over HPLC, such as the use of relatively non-toxic aqueous buffers, as opposed to organic solvents, which obviates the use of expensive HPLC grade solvents making CE more cost effective. Cyclizine was analyzed in 50 mM phosphate buffer (pH 2.3) and run at an applied voltage 25 kV. Detection sensitivity was enhanced by using a wavelength of 200 nm and samples were loaded hydrodynamically onto an uncoated fused-silica capillary (60 cm×50 mm i.d.). Chlorcyclizine was used as the internal standard and resolution of both compounds was achieved in less than 7 min. Stress testing was undertaken in order to investigate the appearance of breakdown products. The method has the requisite accuracy, selectivity, sensitivity and precision to assay cyclizine in tablets and suppositories. Degradation products resulting from the stress studies did not interfere with the detection of cyclizine and the assay is thus stability-indicating.
- Full Text:
- Date Issued: 2004
- Authors: Mohammadi, I , Kanfer, Isadore , Walker, Roderick B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6406 , http://hdl.handle.net/10962/d1006479
- Description: Current compendial methods of assay for the analysis of cyclizine tablets involve the use of UV spectrophotometry. Since this is a non-selective technique its application to more complex dosage forms, such as suppositories, is unlikely to be appropriate. There is therefore a need for the development of a highly specific quantitative analytical method, such as high performance liquid chromatography (HPLC) or capillary electrophoresis (CE). The latter technique was chosen in view of some specific advantages over HPLC, such as the use of relatively non-toxic aqueous buffers, as opposed to organic solvents, which obviates the use of expensive HPLC grade solvents making CE more cost effective. Cyclizine was analyzed in 50 mM phosphate buffer (pH 2.3) and run at an applied voltage 25 kV. Detection sensitivity was enhanced by using a wavelength of 200 nm and samples were loaded hydrodynamically onto an uncoated fused-silica capillary (60 cm×50 mm i.d.). Chlorcyclizine was used as the internal standard and resolution of both compounds was achieved in less than 7 min. Stress testing was undertaken in order to investigate the appearance of breakdown products. The method has the requisite accuracy, selectivity, sensitivity and precision to assay cyclizine in tablets and suppositories. Degradation products resulting from the stress studies did not interfere with the detection of cyclizine and the assay is thus stability-indicating.
- Full Text:
- Date Issued: 2004
The bells of north western Transkei, South Africa
- Authors: Lewis, Colin A
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6183 , http://hdl.handle.net/10962/d1012379 , http://www.ringingworld.co.uk
- Description: [From Introduction] Few of the many visitors to South Africa journey into the isolated country east of Queenstown and south of Elliot, in the rugged basin and range country of that part of the Transkei. That is largely a forgotten land, hidden south of the Mount Arthur range from the rolling grasslands of the Drakensburg foothills and their commercial farms. , Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa.
- Full Text:
- Date Issued: 2004
- Authors: Lewis, Colin A
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6183 , http://hdl.handle.net/10962/d1012379 , http://www.ringingworld.co.uk
- Description: [From Introduction] Few of the many visitors to South Africa journey into the isolated country east of Queenstown and south of Elliot, in the rugged basin and range country of that part of the Transkei. That is largely a forgotten land, hidden south of the Mount Arthur range from the rolling grasslands of the Drakensburg foothills and their commercial farms. , Colin Lewis was Professor of Geography at Rhodes University, Grahamstown, South Africa from 1989 until his retirement at the end of 2007. In 1990, with the strong support of the incumbent Vice-Chancellor, Dr Derek Henderson, he instigated the Certificate in Change Ringing (Church Bell Ringing) in the Rhodes University Department of Music and Musicology - the first such course to be offered in Africa. Since that date he has lectured in the basic theory, and taught the practice of change ringing. He is the Ringing Master of the Cathedral of St Michael and St George, Grahamstown, South Africa.
- Full Text:
- Date Issued: 2004
Pictograms for conveying medicine instructions: comprehension in various South African language groups
- Dowse, Roslind, Ehlers, Martina S
- Authors: Dowse, Roslind , Ehlers, Martina S
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6354 , http://hdl.handle.net/10962/d1006038
- Description: The comprehension of medicine instructions is essential for the safe and effective use of medicines. In cases where low literacy constitutes a possible barrier to understanding written medicine information fully, the inclusion of pictograms may facilitate comprehension. Twenty-three internationally available pictograms and 23 corresponding locally developed images were evaluated in 304 low-literate respondents from eight different South African language groups. Demographic data were collected and an English literacy test was administered to those respondents who had stated that they could read English. Interviewees were shown the 46 pictograms in random order and were asked for their interpretation. Preference for either the international or local version was assessed. Correct interpretation of individual pictograms ranged from 14% to 97%. Images which had been developed locally were more successful in eliciting correct interpretations than those obtained from an international source (USP pictograms). Only 2 of the 23 USP pictograms achieved the 85% criterion of the American National Standards Institute compared with 12 of 23 locally developed counterparts. Local pictograms were preferred over the American ones in all cases. Standard of education had a significant influence on interpretation, whereas no significant differences in interpretation could be attributed to cultural diversity between the African language groups. Almost all respondents (98%) reacted positively to the idea of having pictograms on their medicine labels. The success of the local pictograms highlighted the value of a rigorous and consultative design and test process. Results from one African language group can reliably be extrapolated to other groups in South Africa.
- Full Text:
- Date Issued: 2004
- Authors: Dowse, Roslind , Ehlers, Martina S
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6354 , http://hdl.handle.net/10962/d1006038
- Description: The comprehension of medicine instructions is essential for the safe and effective use of medicines. In cases where low literacy constitutes a possible barrier to understanding written medicine information fully, the inclusion of pictograms may facilitate comprehension. Twenty-three internationally available pictograms and 23 corresponding locally developed images were evaluated in 304 low-literate respondents from eight different South African language groups. Demographic data were collected and an English literacy test was administered to those respondents who had stated that they could read English. Interviewees were shown the 46 pictograms in random order and were asked for their interpretation. Preference for either the international or local version was assessed. Correct interpretation of individual pictograms ranged from 14% to 97%. Images which had been developed locally were more successful in eliciting correct interpretations than those obtained from an international source (USP pictograms). Only 2 of the 23 USP pictograms achieved the 85% criterion of the American National Standards Institute compared with 12 of 23 locally developed counterparts. Local pictograms were preferred over the American ones in all cases. Standard of education had a significant influence on interpretation, whereas no significant differences in interpretation could be attributed to cultural diversity between the African language groups. Almost all respondents (98%) reacted positively to the idea of having pictograms on their medicine labels. The success of the local pictograms highlighted the value of a rigorous and consultative design and test process. Results from one African language group can reliably be extrapolated to other groups in South Africa.
- Full Text:
- Date Issued: 2004
Concerning secondary thermoluminescence peaks in α-Al_2_O_3_:C
- Authors: Chithambo, Makaiko L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6793 , http://hdl.handle.net/10962/d1003823
- Description: Thermoluminescence characteristics of two subsidiary glow peaks, one below 100°C and the other above 300°C, have been studied for measurements between 30°C and 500°C in α-Al_2_O_3_:C. The thermoluminescence intensity of the lower temperature peak decreased with storage with a half-life of about 150 s. In contrast, the intensity of the higher temperature peak increased with storage towards some maximum. The peak-temperature of each of the secondary glow peaks was essentially constant with dose, whereas that of the main peak decreased with irradiation. The dose response for the three peaks was similar except for sublinear growth in the higher temperature peak at low dose values. These effects are discussed in terms of changes in the concentration of F+ luminescence precursors brought about by competitive electron retrapping at deep electron-traps or hole-traps. This work refines the physics and application of α-Al_2_O_3_:C luminescence in radiation dosimetry.
- Full Text:
- Date Issued: 2004
- Authors: Chithambo, Makaiko L
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6793 , http://hdl.handle.net/10962/d1003823
- Description: Thermoluminescence characteristics of two subsidiary glow peaks, one below 100°C and the other above 300°C, have been studied for measurements between 30°C and 500°C in α-Al_2_O_3_:C. The thermoluminescence intensity of the lower temperature peak decreased with storage with a half-life of about 150 s. In contrast, the intensity of the higher temperature peak increased with storage towards some maximum. The peak-temperature of each of the secondary glow peaks was essentially constant with dose, whereas that of the main peak decreased with irradiation. The dose response for the three peaks was similar except for sublinear growth in the higher temperature peak at low dose values. These effects are discussed in terms of changes in the concentration of F+ luminescence precursors brought about by competitive electron retrapping at deep electron-traps or hole-traps. This work refines the physics and application of α-Al_2_O_3_:C luminescence in radiation dosimetry.
- Full Text:
- Date Issued: 2004
Metus in the Roman law of obligations
- Authors: Glover, Graham B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6336 , http://hdl.handle.net/10962/d1012401
- Description: [From the introduction]: An entire title of book four of Justinian’s Digest is devoted to explaining the doctrine of metus as it was understood at the time of the codification of the Roman law. That title begins with the following statement: "The praetor says: 'I will not hold valid what has been done under duress.'" This unequivocal statement of legal principle illustrates, in very general terms, that by the time the Corpus Iuris Civilis was compiled, the Romans disapproved of persons using threats to inspire the creation of legal obligations, and that it was possible to avoid the legal consequences of an obligation because it was induced by metus. The Corpus Iuris Civilis remains our most valuable source of authority with regard to how duress cases were treated in Roman times. But the relevant textual sources pose some fundamental difficulties. Far from containing a coherent, structured analysis of the law, the relevant passages in fact amount to a jigsaw-puzzle of uncoordinated, haphazard, and occasionally contradictory legal propositions
- Full Text:
- Date Issued: 2004
- Authors: Glover, Graham B
- Date: 2004
- Language: English
- Type: Article
- Identifier: vital:6336 , http://hdl.handle.net/10962/d1012401
- Description: [From the introduction]: An entire title of book four of Justinian’s Digest is devoted to explaining the doctrine of metus as it was understood at the time of the codification of the Roman law. That title begins with the following statement: "The praetor says: 'I will not hold valid what has been done under duress.'" This unequivocal statement of legal principle illustrates, in very general terms, that by the time the Corpus Iuris Civilis was compiled, the Romans disapproved of persons using threats to inspire the creation of legal obligations, and that it was possible to avoid the legal consequences of an obligation because it was induced by metus. The Corpus Iuris Civilis remains our most valuable source of authority with regard to how duress cases were treated in Roman times. But the relevant textual sources pose some fundamental difficulties. Far from containing a coherent, structured analysis of the law, the relevant passages in fact amount to a jigsaw-puzzle of uncoordinated, haphazard, and occasionally contradictory legal propositions
- Full Text:
- Date Issued: 2004