Water-soluble phthalocyanines mediated photodynamic effect on mesothelioma cells
- Saydan, Nil, Durmus, Mahmut, Dizge, Meltem G, Yaman, Hanif, Gürek, Ayşe G, Antunes, Edith M, Nyokong, Tebello, Ahsen, Vefa
- Authors: Saydan, Nil , Durmus, Mahmut , Dizge, Meltem G , Yaman, Hanif , Gürek, Ayşe G , Antunes, Edith M , Nyokong, Tebello , Ahsen, Vefa
- Date: 2009
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/263480 , vital:53631 , xlink:href="https://doi.org/10.1142/S1088424609000863"
- Description: The new peripherally 2-mercaptopyridine tetrasubstituted zinc phthalocyanine (2) and its quaternized derivative (3) have been synthesized and characterized by elemental analysis, IR, 1H NMR spectroscopy, electronic spectroscopy and mass spectra. The quaternized compound (3) shows excellent solubility in water, which makes it a potential photosensitizer for use in photodynamic therapy (PDT) of cancer. Fluorescence and singlet oxygen quantum yield measurements were conducted on 2-mercaptopyridine appended zinc phthalocyanines in dimethylsulphoxide (DMSO) for both the non-ionic (2) and quaternized (3) derivatives, and in aqueous media for the water-soluble complex 3. General trends are described for fluorescence and singlet oxygen quantum yields of these compounds. In this study, the cells were incubated with a novel water-soluble zinc phthalocyanine derivative (3) and thereafter the cells were illuminated using broad-band incoherent light source of various energy levels. Cytotoxicity of PDT on two pleural malign mesothelioma cell lines was determined by colorimetric proliferation assay. In addition, after PDT treatment, determination of activity matrix metalloproteinases (MMPs) were evaluated using gelatine zymography.
- Full Text:
- Date Issued: 2009
- Authors: Saydan, Nil , Durmus, Mahmut , Dizge, Meltem G , Yaman, Hanif , Gürek, Ayşe G , Antunes, Edith M , Nyokong, Tebello , Ahsen, Vefa
- Date: 2009
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/263480 , vital:53631 , xlink:href="https://doi.org/10.1142/S1088424609000863"
- Description: The new peripherally 2-mercaptopyridine tetrasubstituted zinc phthalocyanine (2) and its quaternized derivative (3) have been synthesized and characterized by elemental analysis, IR, 1H NMR spectroscopy, electronic spectroscopy and mass spectra. The quaternized compound (3) shows excellent solubility in water, which makes it a potential photosensitizer for use in photodynamic therapy (PDT) of cancer. Fluorescence and singlet oxygen quantum yield measurements were conducted on 2-mercaptopyridine appended zinc phthalocyanines in dimethylsulphoxide (DMSO) for both the non-ionic (2) and quaternized (3) derivatives, and in aqueous media for the water-soluble complex 3. General trends are described for fluorescence and singlet oxygen quantum yields of these compounds. In this study, the cells were incubated with a novel water-soluble zinc phthalocyanine derivative (3) and thereafter the cells were illuminated using broad-band incoherent light source of various energy levels. Cytotoxicity of PDT on two pleural malign mesothelioma cell lines was determined by colorimetric proliferation assay. In addition, after PDT treatment, determination of activity matrix metalloproteinases (MMPs) were evaluated using gelatine zymography.
- Full Text:
- Date Issued: 2009
Main thesis title
- Authors: Tsamago, Hodi, Elias
- Date: 2022-12
- Subjects: Technology integration , SOLEs pedagogy , Metacognitive
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/60549 , vital:65833
- Description: The study was carried out to investigate the effect of the use of technology in self-organised learning environments (SOLEs) (in Physical Sciences classrooms) on learners’ metacognitive skills. The study contributes by identifying a technology-enhanced pedagogy that can effectively equip learners with metacognitive skills, which many studies have reported as having an effect on Physical Sciences learners’ conceptual understanding. The study followed an experimental (control group quasi-experimental) methods design, in which both qualitative and quantitative data were collected and analysed. A multistep stratified sampling method (which caters for both quantitative and qualitative facets) was employed to choose four schools (two rural and two urban) to participate in the study. These schools were randomly chosen from the population of all schools offering Physical Sciences in Grade 11 in the Capricorn District of Limpopo Province, South Africa were assigned to urban experimental group and rural experimental group (UEG and REG) and urban control group and rural control group (UCG and RCG) using geographical demographics. The participants were selected using both simple random sampling (for quantitative methods) and purposive sampling (for qualitative methods). The experimental groups were taught by the researcher using self-organised learning environments (SOLEs) pedagogy, while control groups were taught (also by the researcher of the study) using a traditional chalk-and-talk approach. A Physical Sciences concepts pre-/post-test and the Metacognitive Self-Assessment Scale (MSAS) questionnaire were used to glean the quantitative data, while focus group interviews (FGIs) were used to obtain the qualitative data. The analysis of the quantitative data employed both descriptive (mean, standard deviation and graphs) and inferential (both parametric t-test and non-parametric Kruskal-Wallis and Wilcoxon signed-rank tests) statistics computed using the SPSS package version 22, while qualitative data were analysed thematically using coding techniques (applied on a sentence-by-sentence basis) after the transcription of the recorded FGIs. The study found that SOLEs pedagogy improves learners’ metacognitive skills, leading to better Physical Sciences conceptual understanding. In addition, the results indicate that all v aspects of metacognitive skills improved in experimental groups; however, certain aspects exhibited outstanding improvement such as “Respect shown to myself”; “Respect shown to others”; “Respect shown for empathy towards others” and “Respect shown towards problem solving”. Furthermore, the results of the FGIs revealed that a plausible explanation for the ability of SOLEs pedagogy to enhance metacognitive skills lies in its effortlessness to enable learners to link their classroom experiences to real-life experiences; simulate practical work; adapt to collaborative learning; use multiple channels for receiving information; and reducing learners’ reliance on the teacher. Hence, this study recommends the implementation of SOLEs pedagogy in the Physical Sciences classroom to improve learners’ metacognitive skills and conceptual understanding. However, the study had limitations, some of which included the sample size (which has an effect on the degree of generalisability of the research findings) and the period during which SOLEs pedagogy was implemented which might not have been long enough to exhaust its effect on metacognitive skills. Accordingly, further studies employing a longitudinal study design with a sample size bigger than 350 participants would be useful in understanding the effects of SOLEs pedagogy on metacognitive skills and improving the generalisability of research findings , Thesis (PhD) -- Faculty of education, 2022
- Full Text:
- Date Issued: 2022-12
- Authors: Tsamago, Hodi, Elias
- Date: 2022-12
- Subjects: Technology integration , SOLEs pedagogy , Metacognitive
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/60549 , vital:65833
- Description: The study was carried out to investigate the effect of the use of technology in self-organised learning environments (SOLEs) (in Physical Sciences classrooms) on learners’ metacognitive skills. The study contributes by identifying a technology-enhanced pedagogy that can effectively equip learners with metacognitive skills, which many studies have reported as having an effect on Physical Sciences learners’ conceptual understanding. The study followed an experimental (control group quasi-experimental) methods design, in which both qualitative and quantitative data were collected and analysed. A multistep stratified sampling method (which caters for both quantitative and qualitative facets) was employed to choose four schools (two rural and two urban) to participate in the study. These schools were randomly chosen from the population of all schools offering Physical Sciences in Grade 11 in the Capricorn District of Limpopo Province, South Africa were assigned to urban experimental group and rural experimental group (UEG and REG) and urban control group and rural control group (UCG and RCG) using geographical demographics. The participants were selected using both simple random sampling (for quantitative methods) and purposive sampling (for qualitative methods). The experimental groups were taught by the researcher using self-organised learning environments (SOLEs) pedagogy, while control groups were taught (also by the researcher of the study) using a traditional chalk-and-talk approach. A Physical Sciences concepts pre-/post-test and the Metacognitive Self-Assessment Scale (MSAS) questionnaire were used to glean the quantitative data, while focus group interviews (FGIs) were used to obtain the qualitative data. The analysis of the quantitative data employed both descriptive (mean, standard deviation and graphs) and inferential (both parametric t-test and non-parametric Kruskal-Wallis and Wilcoxon signed-rank tests) statistics computed using the SPSS package version 22, while qualitative data were analysed thematically using coding techniques (applied on a sentence-by-sentence basis) after the transcription of the recorded FGIs. The study found that SOLEs pedagogy improves learners’ metacognitive skills, leading to better Physical Sciences conceptual understanding. In addition, the results indicate that all v aspects of metacognitive skills improved in experimental groups; however, certain aspects exhibited outstanding improvement such as “Respect shown to myself”; “Respect shown to others”; “Respect shown for empathy towards others” and “Respect shown towards problem solving”. Furthermore, the results of the FGIs revealed that a plausible explanation for the ability of SOLEs pedagogy to enhance metacognitive skills lies in its effortlessness to enable learners to link their classroom experiences to real-life experiences; simulate practical work; adapt to collaborative learning; use multiple channels for receiving information; and reducing learners’ reliance on the teacher. Hence, this study recommends the implementation of SOLEs pedagogy in the Physical Sciences classroom to improve learners’ metacognitive skills and conceptual understanding. However, the study had limitations, some of which included the sample size (which has an effect on the degree of generalisability of the research findings) and the period during which SOLEs pedagogy was implemented which might not have been long enough to exhaust its effect on metacognitive skills. Accordingly, further studies employing a longitudinal study design with a sample size bigger than 350 participants would be useful in understanding the effects of SOLEs pedagogy on metacognitive skills and improving the generalisability of research findings , Thesis (PhD) -- Faculty of education, 2022
- Full Text:
- Date Issued: 2022-12
Iron perchlorophthalocyanine and tetrasulfophthalocyanine catalyzed oxidation of cyclohexane using hydrogen peroxide, chloroperoxybenzoic acid and tert-butylhydroperoxide as oxidants
- Grootboom, Natasha, Nyokong, Tebello
- Authors: Grootboom, Natasha , Nyokong, Tebello
- Date: 2002
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/289606 , vital:56653 , xlink:href="https://doi.org/10.1016/S1381-1169(01)00404-6"
- Description: Polychlorophthalocyanine (Cl16PcFeII) and tetrasulfophthalocyanine ([FeIITSPc]4−) complexes of iron are employed as catalysts for the oxidation of cyclohexane using tert-butyl hydroperoxide (TBHP), m-chloroperoxybenzoic acid (m-CPBA) and hydrogen peroxide as oxidants. Catalysis using the Cl16PcFeII was performed in a dimethylformamide:dichloromethane (3:7) solvent mixture. For the [FeIITSPc]4−catalyst, a water:methanol (1:9) mixture was employed. The products of the catalysis are cyclohexanone, cyclohexanol and cyclohexanediol. The relative yields of the products depended on oxidant and the catalyst. TBHP was found to be the best oxidant since minimal destruction of the catalyst and higher selectivity in the products were observed when this oxidant was employed. The mechanism of the oxidation of cyclohexane in the presence of the Cl16PcFeII and [FeIITSPc]4− involves the oxidation of these catalysts, forming an Fe(III) phthalocyanine species as an intermediate. Higher yields were observed when [FeTSPc]4− was employed as a catalyst, which is more soluble than the perchlorinated iron phthalocyanine catalyst.
- Full Text:
- Date Issued: 2002
- Authors: Grootboom, Natasha , Nyokong, Tebello
- Date: 2002
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/289606 , vital:56653 , xlink:href="https://doi.org/10.1016/S1381-1169(01)00404-6"
- Description: Polychlorophthalocyanine (Cl16PcFeII) and tetrasulfophthalocyanine ([FeIITSPc]4−) complexes of iron are employed as catalysts for the oxidation of cyclohexane using tert-butyl hydroperoxide (TBHP), m-chloroperoxybenzoic acid (m-CPBA) and hydrogen peroxide as oxidants. Catalysis using the Cl16PcFeII was performed in a dimethylformamide:dichloromethane (3:7) solvent mixture. For the [FeIITSPc]4−catalyst, a water:methanol (1:9) mixture was employed. The products of the catalysis are cyclohexanone, cyclohexanol and cyclohexanediol. The relative yields of the products depended on oxidant and the catalyst. TBHP was found to be the best oxidant since minimal destruction of the catalyst and higher selectivity in the products were observed when this oxidant was employed. The mechanism of the oxidation of cyclohexane in the presence of the Cl16PcFeII and [FeIITSPc]4− involves the oxidation of these catalysts, forming an Fe(III) phthalocyanine species as an intermediate. Higher yields were observed when [FeTSPc]4− was employed as a catalyst, which is more soluble than the perchlorinated iron phthalocyanine catalyst.
- Full Text:
- Date Issued: 2002
Ultrasensitive detection of prostate-specific antigen using glucose-encapsulated nanoliposomes anti-PSA polyclonal antibody as detection nanobioprobes
- Mwanza, Daniel, Mfamela, Nololo, Adeniyi, Omotayo, Nyokong, Tebello, Mashazi, Philani N
- Authors: Mwanza, Daniel , Mfamela, Nololo , Adeniyi, Omotayo , Nyokong, Tebello , Mashazi, Philani N
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/300268 , vital:57911 , xlink:href="https://doi.org/10.1016/j.talanta.2022.123483"
- Description: In this work, the preparation of glucose encapsulating nanoliposomes was achieved using two different lipid formulations, labelled as F1 and F2. Both formulations contained phosphatidylcholine (PC), oleylamido-4-butanoic acid (OABA) and in addition, F1 had cholesterol (CHO) while F2 contained cholesteroyl hemisussinate (CHEMS). These formulations were studied for their pH sensitivity and controlled release of encapsulated glucose for indirect detection of prostate-specific antigen (PSA) using sandwich immunoassay. As a signal generator, encapsulated glucose in nanoliposomes was quantified directly using the personal glucose meter (PGM) and colorimetrically using peroxidase property of horseradish peroxidase (HRP) enzyme and Pd|PdO as nanozymes. Controlled release of the encapsulated glucose was achieved using the pH effect or Triton-X 100 as a surfactant to destabilize the liposomal structure. The F2 formulation showed maximum controlled release at acidic phosphate buffer saline (PBS, pH 5.0). The concentration of encapsulated glucose was found to be high in F2 formulation and these were applied for the indirect detection of PSA. The limit of detection (LOD) values for PSA were found to be 53 fg mL−1, 64 fg mL−1 and 10 fg mL−1 when HRP, Pd|PdO and PGM were respectively used. The detection signal was linear over a wide concentration range for PSA including the clinical range of 4–10 ng mL−1. The HRP system showed low LOD value when compared with Pd|PdO nanozymes. PGM system gave lowest LOD values owing to the sensitivity of the system towards glucose. Pd|PdO nanozyme system showed good stability over a wide temperature up to 80 °C. PGM system required less reaction time (2 min), low reagents and results were readily generated in digital format.
- Full Text:
- Date Issued: 2022
- Authors: Mwanza, Daniel , Mfamela, Nololo , Adeniyi, Omotayo , Nyokong, Tebello , Mashazi, Philani N
- Date: 2022
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/300268 , vital:57911 , xlink:href="https://doi.org/10.1016/j.talanta.2022.123483"
- Description: In this work, the preparation of glucose encapsulating nanoliposomes was achieved using two different lipid formulations, labelled as F1 and F2. Both formulations contained phosphatidylcholine (PC), oleylamido-4-butanoic acid (OABA) and in addition, F1 had cholesterol (CHO) while F2 contained cholesteroyl hemisussinate (CHEMS). These formulations were studied for their pH sensitivity and controlled release of encapsulated glucose for indirect detection of prostate-specific antigen (PSA) using sandwich immunoassay. As a signal generator, encapsulated glucose in nanoliposomes was quantified directly using the personal glucose meter (PGM) and colorimetrically using peroxidase property of horseradish peroxidase (HRP) enzyme and Pd|PdO as nanozymes. Controlled release of the encapsulated glucose was achieved using the pH effect or Triton-X 100 as a surfactant to destabilize the liposomal structure. The F2 formulation showed maximum controlled release at acidic phosphate buffer saline (PBS, pH 5.0). The concentration of encapsulated glucose was found to be high in F2 formulation and these were applied for the indirect detection of PSA. The limit of detection (LOD) values for PSA were found to be 53 fg mL−1, 64 fg mL−1 and 10 fg mL−1 when HRP, Pd|PdO and PGM were respectively used. The detection signal was linear over a wide concentration range for PSA including the clinical range of 4–10 ng mL−1. The HRP system showed low LOD value when compared with Pd|PdO nanozymes. PGM system gave lowest LOD values owing to the sensitivity of the system towards glucose. Pd|PdO nanozyme system showed good stability over a wide temperature up to 80 °C. PGM system required less reaction time (2 min), low reagents and results were readily generated in digital format.
- Full Text:
- Date Issued: 2022
“Turn on” fluorescence enhancement of Zn octacarboxyphthaloyanine-graphene oxide conjugates by hydrogen peroxide
- Shumba, Munyaradzi, Mashazi, Philani N, Nyokong, Tebello
- Authors: Shumba, Munyaradzi , Mashazi, Philani N , Nyokong, Tebello
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/190438 , vital:44994 , xlink:href="https://doi.org/10.1016/j.jlumin.2015.11.001"
- Description: Zn octacarboxy phthalocyanine-reduced graphene oxide or graphene oxide conjugates were characterized by absorption spectroscopy, transmission electron microscopy, fluorescence spectroscopy, X-ray diffraction, thermo gravimetric analysis and X-ray photon spectroscopy. The presence of reduced graphene oxide or graphene oxide resulted in the quenching (turn on) of Zn octacarboxy phthalocyanine fluorescence which can be explained by photoinduced electron transfer. Zn octacarboxy phthalocyaninereduced graphene oxide or graphene oxide conjugates “turned on” fluorescence showed a linear response to hydrogen peroxide hence their potential to be used as sensors. The nanoprobe developed showed high selectivity towards hydrogen peroxide in the presence of physiological interferences.
- Full Text:
- Date Issued: 2016
- Authors: Shumba, Munyaradzi , Mashazi, Philani N , Nyokong, Tebello
- Date: 2016
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/190438 , vital:44994 , xlink:href="https://doi.org/10.1016/j.jlumin.2015.11.001"
- Description: Zn octacarboxy phthalocyanine-reduced graphene oxide or graphene oxide conjugates were characterized by absorption spectroscopy, transmission electron microscopy, fluorescence spectroscopy, X-ray diffraction, thermo gravimetric analysis and X-ray photon spectroscopy. The presence of reduced graphene oxide or graphene oxide resulted in the quenching (turn on) of Zn octacarboxy phthalocyanine fluorescence which can be explained by photoinduced electron transfer. Zn octacarboxy phthalocyaninereduced graphene oxide or graphene oxide conjugates “turned on” fluorescence showed a linear response to hydrogen peroxide hence their potential to be used as sensors. The nanoprobe developed showed high selectivity towards hydrogen peroxide in the presence of physiological interferences.
- Full Text:
- Date Issued: 2016
A framework for the successful management of the service suppliers in the public sector in South Africa
- Authors: Fudu, Anele George
- Date: 2021-04
- Subjects: Management , Business logistics , Government business enterprises -- Management
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/51411 , vital:43272
- Description: The Public sector outsources the service to the private service suppliers through tendering and the awarding of contracts to the successful service providers. There is a lot of money budgeted and spent on service providers; therefore, there is a great need to manage the service providers successfully, in order to deliver a reliable service to the community; and to reduce the cost thereof. The study focused on the successful management of the service suppliers, in order to deliver contract deliverables. Poor performance of the service providers might well lead to schedule overruns, contract over-expenditure and contract cancellations. Inadequate performance management causes service suppliers not to perform at their optimum level. The study aimed to contribute to the development of the framework for performance management of the service suppliers in the public sector in South Africa. The primary objectives of the study were to investigate and develop a framework for managing and enhancing the performance of the service suppliers in the public sector. More specifically, the study investigated the influence of scope of work, a contract strategy, performance management, risk management and change management. The study sought to formulate a structured and practical approach on how to manage service suppliers to the public sector. The study will seek to understand what influences the success for the win-win approach in the Public Sector and Services Suppliers – so that both parties can see themselves as partners in the delivery of the services. The sample consists of 70 employees across all the public sector in South Africa, which consists of national government, provincial municipalities, district municipalities, local government and State-owned companies. The study targeted those respondents involved in the management of the service suppliers to the public study. The empirical results show that the management of the service providers’ performance in the public sector is critical to the service delivery and the management of the final cost. , Thesis (MBA) -- Faculty of Business and Economic Sciences, Business Administration, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Fudu, Anele George
- Date: 2021-04
- Subjects: Management , Business logistics , Government business enterprises -- Management
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/51411 , vital:43272
- Description: The Public sector outsources the service to the private service suppliers through tendering and the awarding of contracts to the successful service providers. There is a lot of money budgeted and spent on service providers; therefore, there is a great need to manage the service providers successfully, in order to deliver a reliable service to the community; and to reduce the cost thereof. The study focused on the successful management of the service suppliers, in order to deliver contract deliverables. Poor performance of the service providers might well lead to schedule overruns, contract over-expenditure and contract cancellations. Inadequate performance management causes service suppliers not to perform at their optimum level. The study aimed to contribute to the development of the framework for performance management of the service suppliers in the public sector in South Africa. The primary objectives of the study were to investigate and develop a framework for managing and enhancing the performance of the service suppliers in the public sector. More specifically, the study investigated the influence of scope of work, a contract strategy, performance management, risk management and change management. The study sought to formulate a structured and practical approach on how to manage service suppliers to the public sector. The study will seek to understand what influences the success for the win-win approach in the Public Sector and Services Suppliers – so that both parties can see themselves as partners in the delivery of the services. The sample consists of 70 employees across all the public sector in South Africa, which consists of national government, provincial municipalities, district municipalities, local government and State-owned companies. The study targeted those respondents involved in the management of the service suppliers to the public study. The empirical results show that the management of the service providers’ performance in the public sector is critical to the service delivery and the management of the final cost. , Thesis (MBA) -- Faculty of Business and Economic Sciences, Business Administration, 2021
- Full Text:
- Date Issued: 2021-04
Spatial modelling of accessibility to tuberculosis treatment: the case of Ngaka Modiri Molema District
- Authors: Ramotsongwa, Karabo Naome
- Date: 2022-04
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/55435 , vital:52000
- Description: Accessibility to healthcare refers to the availability, or the provision of healthcare-byhealthcare professionals and stakeholders and individuals' ability to obtain care and treatment. It affects overall physical, social, and mental health; disease and disability prevention; detection and treatment of health conditions; standard of living; preventable death; and life expectancy, and it is crucial to the performance of health care systems around the world. If healthcare services are available and are in sufficient supply, people will be able to seek health care, and a population will have access to services. The leading cause of death globally is Tuberculosis (TB) and South Africa is amongst the top 5 countries most affected by TB. This is aggravated by high HIV/AIDS statistics. Children belowthe age of 4, between the ages of 4- 15, and women and men of working ages are highly affected by TB and it is the primary cause of death in these groups in the Ngaka Modiri Molema District. This study used study tools like Spatial Modelling, Geographic Information Systems and software like ArcGIS 10.5, TerrSet IDRISI 18.30, and secondary data from the North West Departmentof Health (Tier.net &DHIS) and also TB patients’ home addresses to investigate the accessibility of TB treatment in Ngaka Modiri Molema, in order to spatially visualize the distribution of a communicable disease like TB and public healthcare facilities in the Ngaka Modiri Molema (NMM) District and suggest optimum sites for hospital facilities. , Thesis (MSc) -- Faculty of Science, School of Environmental Sciences, 2022
- Full Text:
- Date Issued: 2022-04
- Authors: Ramotsongwa, Karabo Naome
- Date: 2022-04
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/55435 , vital:52000
- Description: Accessibility to healthcare refers to the availability, or the provision of healthcare-byhealthcare professionals and stakeholders and individuals' ability to obtain care and treatment. It affects overall physical, social, and mental health; disease and disability prevention; detection and treatment of health conditions; standard of living; preventable death; and life expectancy, and it is crucial to the performance of health care systems around the world. If healthcare services are available and are in sufficient supply, people will be able to seek health care, and a population will have access to services. The leading cause of death globally is Tuberculosis (TB) and South Africa is amongst the top 5 countries most affected by TB. This is aggravated by high HIV/AIDS statistics. Children belowthe age of 4, between the ages of 4- 15, and women and men of working ages are highly affected by TB and it is the primary cause of death in these groups in the Ngaka Modiri Molema District. This study used study tools like Spatial Modelling, Geographic Information Systems and software like ArcGIS 10.5, TerrSet IDRISI 18.30, and secondary data from the North West Departmentof Health (Tier.net &DHIS) and also TB patients’ home addresses to investigate the accessibility of TB treatment in Ngaka Modiri Molema, in order to spatially visualize the distribution of a communicable disease like TB and public healthcare facilities in the Ngaka Modiri Molema (NMM) District and suggest optimum sites for hospital facilities. , Thesis (MSc) -- Faculty of Science, School of Environmental Sciences, 2022
- Full Text:
- Date Issued: 2022-04
Indigenous knowledge systems and gender relations interface and its implications for food security: the case of Khambashe rural households in the Amathole District, South Africa
- Garutsa, T C https://orcid.org/0000-0003-1904-2764
- Authors: Garutsa, T C https://orcid.org/0000-0003-1904-2764
- Date: 2015-01
- Subjects: Food security -- South Africa -- Eastern Cape , Indigenous peoples -- South Africa -- Eastern Cape
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26581 , vital:65660
- Description: The aim of this study was to find out about how the intersection of indigenous knowledge systems and gender relations affects food security in the rural households of the Khambashe village in the Eastern Cape. The focus is on food security-related indigenous knowledge utilized by women rather than the general indigenous knowledge of the people in the Eastern Cape. Ample literature exists on food security and gender, food security and indigenous knowledge systems and the role of gender dynamics in the application of indigenous knowledge systems. However, there is dearth of literature on studies on the role of the indigenous knowledge systems-gender relations interface in food security. Hence this study was directed at investigating the indigenous knowledge systems-gender dynamics interplay and its implications for food security and sustainable development with specific reference to the rural households of Khambashe village of the Eastern Cape Province. Furthermore, the study seeks to determine factors accounting for the attrition of women’s indigenous knowledge in food production systems of the Khambashe rural households. The main position advanced in this thesis is that domination coupled with marginalisation of women and indigenous knowledge systems by hegemonic Western power/knowledge and traditional African practices account for challenges faced by rural households with regard to food security and sustainable livelihoods. Put differently, the core argument of this study is that the intersection between gender and indigenous knowledge systems has two opposing possibilities for food security. On the one hand, through the various roles of women in the application of indigenous knowledge systems in rural areas, the indigenous knowledge and gender relations interplay can operate to enhance the likelihood of achieving sustainable rural livelihoods and hence food security. On the other hand, gender oppression, subjugation, exclusion and marginalization through various practices such as the utilization of discriminatory patriarchal cultural values and norms can inhibit the application of the rich folk knowledge reservoir of ideas held by women in food production processes. Key illustrative examples of the constraints imposed by cultural traditions that pose problems for the realization of sustainable rural livelihoods are cultural practices which prohibit women to inter alia own and inherit land. These cultural practices also deprive women the liberty to make their own decisions without the consultation of men despite being sole providers of their own households. In other words, lack of access to assets and other resources owing to the marginalization of local knowledge by the dominant Western-based scientific knowledge systems and culturally-derived gender discriminatory practices make the role of women in the process of utilizing indigenous knowledge systems for the purposes of food security difficult. The theoretical framework of this study is drawn from the post-development discourse derived from Foucault’s archaeology of power and knowledge, ecofeminism and African feminism. Such a framework has a utility to reinvigorate marginalised indigenous knowledge and thereby help women reclaim their leadership in processes of ensuring food security. In a situation where indigenous knowledge systems have been excluded and subjugated by the dominant Western knowledge systems, an extended post-development discourse of this nature is transformative. While Foucault’s theory will provide key insights around power/knowledge dynamics and issues, ecofeminism and African feminism will extend these insights in the exploration of the patterns of power in both the knowledge and gender relations domains. In fact interactions in food production processes are embedded in systematized knowledge and traditional gender relations. Hence, in order to ensure a deep-going analysis of these phenomena, Foucault’s framework on power/knowledge is augmented by the ideas of ecofeminism and African feminism owing to the fact that systems of domination whether in the knowledge arena or gender relations domain are responsible for the challenges relating to food secure households and sustainable rural livelihoods. The rationale for this approach is that subjugation and marginalization of indigenous knowledge systems by Western hegemonic power/knowledge coupled with exclusionary and discriminatory practices of patriarchal cultural values is seen as inhibiting the proper application of indigenous knowledge in food production processes. The extended post-development discourse adopted for this study takes into consideration the fact that oppression and discrimination the world over has taken the Foucauldian power/knowledge dimension in the sense that women in rural African settings are not only prevented by Western science from the application of indigenous knowledge for the development of sustainable livelihoods but that their own cultural traditions are also a hindrance towards them owning land and property, making their own decisions without recourse to men and exercising their own authority. A mixed method approach combining qualitative and quantitative research design was utilized in order to gain a full grasp of nuances of the interface between indigenous knowledge and gender dynamics in food production processes in Khambashe. This methodological triangulation was used for purposes of enhancing the capturing of comprehensive data and a holistic understanding of food security issues in the area. Further, owing to the fact that survey questionnaires as research instruments would have not given a voice to women as key research participants and that the deployment of in-depth interviews alone as research tools would have compromised the generalizability of the findings of the study, each of the two research methods were to confirm, clarify, complement, enhance and elaborate the research results of the other. In other words, in order to counterbalance the limitation of questionnaires with regard to artificiality and not affording a voice to research participants in-depth interviews were conducted. The lack of generalizability of the latter was compensated by the high degree of representativity afforded by the use of the former (that is, questionnaires). As already indicated above, the study setting for the empirical data was the Khambashe village in the Eastern Cape. Information gathered included the more positive effects of the IK-gender relations interplay on food security covered in Chapter 7. This chapter described and analysed the various roles women play inter alia animal husbandry, crop production, creation and utilization of indigenous technology in food production processes and in post-harvesting practices. In contrast, chapter 8 investigated and discusses the various constrains which account for the hindrance in the operationalization of IK in food production processes by women. Chief among the identified constrains in Khambashe are the marginalization of local knowledge by hegemonic Western science and the discriminatory traditional practices. The research results of this study show that despite the key role of women in the application of local knowledge, practices and technologies in food production processes, the penetration, colonization and domination of the African socio-economic and cultural sphere by the West has resulted in the deterioration in the use of indigenous knowledge. Imperialistic Western knowledge masquerading as modern science and technology manifested in inter alia chemical fertilizers and modified food is a constraint to the utility of women’s indigenous knowledge and practices that ensures both food security and sustainable development. In view of the fact that failure to utilize readily available indigenous knowledge, practices and technologies owing to the marginalisation of local epistemes by Western science and the discriminatory African traditional practices and gender relations has led to further impoverishment of rural communities, there is a need to both empower women and to revitalize their indigenous knowledge for purposes of food security and sustainable development in rural areas such as Khambashe. , Thesis (PhD) -- Faculty of Social Sciences & Humanities, 2015
- Full Text:
- Date Issued: 2015-01
- Authors: Garutsa, T C https://orcid.org/0000-0003-1904-2764
- Date: 2015-01
- Subjects: Food security -- South Africa -- Eastern Cape , Indigenous peoples -- South Africa -- Eastern Cape
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26581 , vital:65660
- Description: The aim of this study was to find out about how the intersection of indigenous knowledge systems and gender relations affects food security in the rural households of the Khambashe village in the Eastern Cape. The focus is on food security-related indigenous knowledge utilized by women rather than the general indigenous knowledge of the people in the Eastern Cape. Ample literature exists on food security and gender, food security and indigenous knowledge systems and the role of gender dynamics in the application of indigenous knowledge systems. However, there is dearth of literature on studies on the role of the indigenous knowledge systems-gender relations interface in food security. Hence this study was directed at investigating the indigenous knowledge systems-gender dynamics interplay and its implications for food security and sustainable development with specific reference to the rural households of Khambashe village of the Eastern Cape Province. Furthermore, the study seeks to determine factors accounting for the attrition of women’s indigenous knowledge in food production systems of the Khambashe rural households. The main position advanced in this thesis is that domination coupled with marginalisation of women and indigenous knowledge systems by hegemonic Western power/knowledge and traditional African practices account for challenges faced by rural households with regard to food security and sustainable livelihoods. Put differently, the core argument of this study is that the intersection between gender and indigenous knowledge systems has two opposing possibilities for food security. On the one hand, through the various roles of women in the application of indigenous knowledge systems in rural areas, the indigenous knowledge and gender relations interplay can operate to enhance the likelihood of achieving sustainable rural livelihoods and hence food security. On the other hand, gender oppression, subjugation, exclusion and marginalization through various practices such as the utilization of discriminatory patriarchal cultural values and norms can inhibit the application of the rich folk knowledge reservoir of ideas held by women in food production processes. Key illustrative examples of the constraints imposed by cultural traditions that pose problems for the realization of sustainable rural livelihoods are cultural practices which prohibit women to inter alia own and inherit land. These cultural practices also deprive women the liberty to make their own decisions without the consultation of men despite being sole providers of their own households. In other words, lack of access to assets and other resources owing to the marginalization of local knowledge by the dominant Western-based scientific knowledge systems and culturally-derived gender discriminatory practices make the role of women in the process of utilizing indigenous knowledge systems for the purposes of food security difficult. The theoretical framework of this study is drawn from the post-development discourse derived from Foucault’s archaeology of power and knowledge, ecofeminism and African feminism. Such a framework has a utility to reinvigorate marginalised indigenous knowledge and thereby help women reclaim their leadership in processes of ensuring food security. In a situation where indigenous knowledge systems have been excluded and subjugated by the dominant Western knowledge systems, an extended post-development discourse of this nature is transformative. While Foucault’s theory will provide key insights around power/knowledge dynamics and issues, ecofeminism and African feminism will extend these insights in the exploration of the patterns of power in both the knowledge and gender relations domains. In fact interactions in food production processes are embedded in systematized knowledge and traditional gender relations. Hence, in order to ensure a deep-going analysis of these phenomena, Foucault’s framework on power/knowledge is augmented by the ideas of ecofeminism and African feminism owing to the fact that systems of domination whether in the knowledge arena or gender relations domain are responsible for the challenges relating to food secure households and sustainable rural livelihoods. The rationale for this approach is that subjugation and marginalization of indigenous knowledge systems by Western hegemonic power/knowledge coupled with exclusionary and discriminatory practices of patriarchal cultural values is seen as inhibiting the proper application of indigenous knowledge in food production processes. The extended post-development discourse adopted for this study takes into consideration the fact that oppression and discrimination the world over has taken the Foucauldian power/knowledge dimension in the sense that women in rural African settings are not only prevented by Western science from the application of indigenous knowledge for the development of sustainable livelihoods but that their own cultural traditions are also a hindrance towards them owning land and property, making their own decisions without recourse to men and exercising their own authority. A mixed method approach combining qualitative and quantitative research design was utilized in order to gain a full grasp of nuances of the interface between indigenous knowledge and gender dynamics in food production processes in Khambashe. This methodological triangulation was used for purposes of enhancing the capturing of comprehensive data and a holistic understanding of food security issues in the area. Further, owing to the fact that survey questionnaires as research instruments would have not given a voice to women as key research participants and that the deployment of in-depth interviews alone as research tools would have compromised the generalizability of the findings of the study, each of the two research methods were to confirm, clarify, complement, enhance and elaborate the research results of the other. In other words, in order to counterbalance the limitation of questionnaires with regard to artificiality and not affording a voice to research participants in-depth interviews were conducted. The lack of generalizability of the latter was compensated by the high degree of representativity afforded by the use of the former (that is, questionnaires). As already indicated above, the study setting for the empirical data was the Khambashe village in the Eastern Cape. Information gathered included the more positive effects of the IK-gender relations interplay on food security covered in Chapter 7. This chapter described and analysed the various roles women play inter alia animal husbandry, crop production, creation and utilization of indigenous technology in food production processes and in post-harvesting practices. In contrast, chapter 8 investigated and discusses the various constrains which account for the hindrance in the operationalization of IK in food production processes by women. Chief among the identified constrains in Khambashe are the marginalization of local knowledge by hegemonic Western science and the discriminatory traditional practices. The research results of this study show that despite the key role of women in the application of local knowledge, practices and technologies in food production processes, the penetration, colonization and domination of the African socio-economic and cultural sphere by the West has resulted in the deterioration in the use of indigenous knowledge. Imperialistic Western knowledge masquerading as modern science and technology manifested in inter alia chemical fertilizers and modified food is a constraint to the utility of women’s indigenous knowledge and practices that ensures both food security and sustainable development. In view of the fact that failure to utilize readily available indigenous knowledge, practices and technologies owing to the marginalisation of local epistemes by Western science and the discriminatory African traditional practices and gender relations has led to further impoverishment of rural communities, there is a need to both empower women and to revitalize their indigenous knowledge for purposes of food security and sustainable development in rural areas such as Khambashe. , Thesis (PhD) -- Faculty of Social Sciences & Humanities, 2015
- Full Text:
- Date Issued: 2015-01
The relationship between green behaviours and their effect on the performance of small businesses in South Africa
- Authors: Banana, Zingisa
- Date: 2021-01
- Subjects: Small business--Management , Environmental economics
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21377 , vital:48514
- Description: Purpose: Academics and the government are placing more emphasis and importance on the role that enterprises can play in response to challenges of the environment. This study aimed to establish the relationship between green behaviours and the performance of small businesses in South Africa. Green behaviours are measured as consisting of green entrepreneurial orientation, green technology dynamism and green innovation behaviour. Conversely, performance is defined as consisting of environmental performance, objective performance and subjective performance. Design/methodology/approach: To achieve the purpose of this study, the study adopted a positivist paradigm which is motivated by the quantitative approach using a descriptive research design. Self-administered questionnaires were employed with a sample of 180 participants that were randomly selected across small businesses in the Buffalo City Metropolitan Municipality in the Eastern Cape province of South Africa. Findings/results: The major findings of the study, using simple linear regression analysis, revealed that a significant positive relationship between green entrepreneurial orientation and environmental, objective and subjective performance does exist. However, the hierarchical regression analysis results revealed that green technology dynamism and green innovation behaviour do not moderate the relationship between green entrepreneurial orientation and performance as measured by environmental, objective and subjective performance dimensions. Practical implications: Based on the findings of the study, small businesses need to develop policy related to promoting green behaviours, given that green entrepreneurial orientation has been found to be related to performance. Originality/value: The results of this study could guide small business owners and managers in the implementation of environmentally-friendly practices in an effort to reduce green economy issues and environmental problems facing the present generation. , Thesis (MCom) (Business Management) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-01
- Authors: Banana, Zingisa
- Date: 2021-01
- Subjects: Small business--Management , Environmental economics
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/21377 , vital:48514
- Description: Purpose: Academics and the government are placing more emphasis and importance on the role that enterprises can play in response to challenges of the environment. This study aimed to establish the relationship between green behaviours and the performance of small businesses in South Africa. Green behaviours are measured as consisting of green entrepreneurial orientation, green technology dynamism and green innovation behaviour. Conversely, performance is defined as consisting of environmental performance, objective performance and subjective performance. Design/methodology/approach: To achieve the purpose of this study, the study adopted a positivist paradigm which is motivated by the quantitative approach using a descriptive research design. Self-administered questionnaires were employed with a sample of 180 participants that were randomly selected across small businesses in the Buffalo City Metropolitan Municipality in the Eastern Cape province of South Africa. Findings/results: The major findings of the study, using simple linear regression analysis, revealed that a significant positive relationship between green entrepreneurial orientation and environmental, objective and subjective performance does exist. However, the hierarchical regression analysis results revealed that green technology dynamism and green innovation behaviour do not moderate the relationship between green entrepreneurial orientation and performance as measured by environmental, objective and subjective performance dimensions. Practical implications: Based on the findings of the study, small businesses need to develop policy related to promoting green behaviours, given that green entrepreneurial orientation has been found to be related to performance. Originality/value: The results of this study could guide small business owners and managers in the implementation of environmentally-friendly practices in an effort to reduce green economy issues and environmental problems facing the present generation. , Thesis (MCom) (Business Management) -- University of Fort Hare, 2021
- Full Text:
- Date Issued: 2021-01
Syntheses and electrochemical characterization of new water soluble octaarylthiosubstituted manganese phthalocyanines
- Booysen, Irvin N, Matemadombo, Fungisai, Durmus, Mahmut, Nyokong, Tebello
- Authors: Booysen, Irvin N , Matemadombo, Fungisai , Durmus, Mahmut , Nyokong, Tebello
- Date: 2011
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/247614 , vital:51600 , xlink:href="https://doi.org/10.1016/j.dyepig.2010.09.012"
- Description: This paper reports on the synthesis and characterization of new manganese phthalocyanine (MnPc) complexes: 2,3-octakis-[(2-mercaptopyridine) phthalocyaninato] acetato manganese (III) (1) and its quaternized (hence water soluble) derivative: 2,3-octakis-{[(N-methyl-2-mercaptopyridine) phthalocyaninato] acetato manganese (III)} sulphate (2). The complexes were used to form self assembled monolayers (SAMs). Voltammetry proved that both of the SAMs are well packed, strongly passivating and act as selective and efficient barriers to ion permeability. Furthermore, surface coverage studies confirmed that the MPc macrocycles adsorb onto the gold electrode as monolayers. Both MPc SAMs were successfully used as electrochemical sensors of nitrite.
- Full Text:
- Date Issued: 2011
- Authors: Booysen, Irvin N , Matemadombo, Fungisai , Durmus, Mahmut , Nyokong, Tebello
- Date: 2011
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/247614 , vital:51600 , xlink:href="https://doi.org/10.1016/j.dyepig.2010.09.012"
- Description: This paper reports on the synthesis and characterization of new manganese phthalocyanine (MnPc) complexes: 2,3-octakis-[(2-mercaptopyridine) phthalocyaninato] acetato manganese (III) (1) and its quaternized (hence water soluble) derivative: 2,3-octakis-{[(N-methyl-2-mercaptopyridine) phthalocyaninato] acetato manganese (III)} sulphate (2). The complexes were used to form self assembled monolayers (SAMs). Voltammetry proved that both of the SAMs are well packed, strongly passivating and act as selective and efficient barriers to ion permeability. Furthermore, surface coverage studies confirmed that the MPc macrocycles adsorb onto the gold electrode as monolayers. Both MPc SAMs were successfully used as electrochemical sensors of nitrite.
- Full Text:
- Date Issued: 2011
Development and validation of a stability-indicating method for the quantitation of paclitaxel in pharmaceutical dosage forms
- Mohammadi, Ali, Esimaeili, Farnaz, Dinarvand, Rasoul, Atyabi, Fatemeh, Walker, Roderick B
- Authors: Mohammadi, Ali , Esimaeili, Farnaz , Dinarvand, Rasoul , Atyabi, Fatemeh , Walker, Roderick B
- Date: 2009
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184278 , vital:44196 , xlink:href="https://doi.org/10.1093/chromsci/47.7.599"
- Description: A simple, rapid stability-indicating isocratic assay has been developed and validated for the determination of Paclitaxel (PTX) in commercial injection formulations. The assay is performed using a Nucleosil RP-18 (5 µm, 250 × 4.0 mm i.d) column protected by a Nucleosil C18 precolumn (5 µm, 4.0 × 4.0 mm i.d.) with a mobile phase of methanol–water (80:20) and UV detection at 230 nm. The method was found to be specific for PTX in the presence of degradation products with an overall analytical run time of ~ 9 min. Accuracy reported as % bias was found to be 0.1–2.5% bias for all samples tested. Intra-assay precision (repeatability) was found to be 0.22–2.65% RSD, while inter-day precision (intermediate precision) was found to be 1.0–3.0% RSD for the samples studied. The calibration curve was found to be linear with the equation y = 29.78x + 7.65, and a linear regression coefficient of 0.9994 over the concentration range 0.05–20 µg/mL. The limits of quantitation and detection were 0.05 and 0.02 µg/mL, respectively. Taxol (30 mg/5 mL), a commercially available dosage form of PTX, was assayed and 100.6–103.6% of the label claim was recovered.
- Full Text:
- Date Issued: 2009
- Authors: Mohammadi, Ali , Esimaeili, Farnaz , Dinarvand, Rasoul , Atyabi, Fatemeh , Walker, Roderick B
- Date: 2009
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/184278 , vital:44196 , xlink:href="https://doi.org/10.1093/chromsci/47.7.599"
- Description: A simple, rapid stability-indicating isocratic assay has been developed and validated for the determination of Paclitaxel (PTX) in commercial injection formulations. The assay is performed using a Nucleosil RP-18 (5 µm, 250 × 4.0 mm i.d) column protected by a Nucleosil C18 precolumn (5 µm, 4.0 × 4.0 mm i.d.) with a mobile phase of methanol–water (80:20) and UV detection at 230 nm. The method was found to be specific for PTX in the presence of degradation products with an overall analytical run time of ~ 9 min. Accuracy reported as % bias was found to be 0.1–2.5% bias for all samples tested. Intra-assay precision (repeatability) was found to be 0.22–2.65% RSD, while inter-day precision (intermediate precision) was found to be 1.0–3.0% RSD for the samples studied. The calibration curve was found to be linear with the equation y = 29.78x + 7.65, and a linear regression coefficient of 0.9994 over the concentration range 0.05–20 µg/mL. The limits of quantitation and detection were 0.05 and 0.02 µg/mL, respectively. Taxol (30 mg/5 mL), a commercially available dosage form of PTX, was assayed and 100.6–103.6% of the label claim was recovered.
- Full Text:
- Date Issued: 2009
A perfect end: A study of syllable codas in South African Sign Language
- Köhlo, Mikhaela D.K., Siebörger, Ian, Bennett, William G
- Authors: Köhlo, Mikhaela D.K. , Siebörger, Ian , Bennett, William G
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/385295 , vital:68005 , xlink:href="https://www.ajol.info/index.php/splp/article/view/156629"
- Description: South African Sign Language (SASL) is an understudied language with a rich and interesting phonology. For instance, while the language allows onsetless syllables, it does not allow codaless syllables, except in a small class of signs which do not include path movement. This article identifies and defines possible constraints on syllable codas in SASL. Using a video dictionary as data, we have coded handshapes at locations occurring at the onset and coda of the more common signs in the lexicon. In handshape, it has been found that the selected fingers may move to create different handshapes in the coda position, but that these coda handshapes are often [1], [5], [A], [Å] or [S], which are the unmarked handshapes of the non-dominant hand in asymmetrical two-handed signs (Sandler and Lillo-Martin 2006). Furthermore, the joint specification for the selected fingers can also vary in the coda position, but there appear to be strict limitations on which joint combinations are permitted in the onset-coda relationship. There are also constraints on coda location. The major body region can change within a single syllable, and the preferred body regions in the coda position are [body] and [H2]. It is evident not only that handshape and location constraints occur at the coda position, but that these constraints show patterns similar to coda neutralisation in many spoken languages.
- Full Text:
- Date Issued: 2017
- Authors: Köhlo, Mikhaela D.K. , Siebörger, Ian , Bennett, William G
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/385295 , vital:68005 , xlink:href="https://www.ajol.info/index.php/splp/article/view/156629"
- Description: South African Sign Language (SASL) is an understudied language with a rich and interesting phonology. For instance, while the language allows onsetless syllables, it does not allow codaless syllables, except in a small class of signs which do not include path movement. This article identifies and defines possible constraints on syllable codas in SASL. Using a video dictionary as data, we have coded handshapes at locations occurring at the onset and coda of the more common signs in the lexicon. In handshape, it has been found that the selected fingers may move to create different handshapes in the coda position, but that these coda handshapes are often [1], [5], [A], [Å] or [S], which are the unmarked handshapes of the non-dominant hand in asymmetrical two-handed signs (Sandler and Lillo-Martin 2006). Furthermore, the joint specification for the selected fingers can also vary in the coda position, but there appear to be strict limitations on which joint combinations are permitted in the onset-coda relationship. There are also constraints on coda location. The major body region can change within a single syllable, and the preferred body regions in the coda position are [body] and [H2]. It is evident not only that handshape and location constraints occur at the coda position, but that these constraints show patterns similar to coda neutralisation in many spoken languages.
- Full Text:
- Date Issued: 2017
Characterization of bioflocculants produced by consortia of three marine bacteria belonging to the genera bacillus and cobetia previously isolated from the bottom sediment of Algoa Bay in the Eastern Cape Province of South Africa
- Ugbenyen, Anthony Moses https://orcid.org/0000-0002-1381-3428
- Authors: Ugbenyen, Anthony Moses https://orcid.org/0000-0002-1381-3428
- Date: 2013
- Subjects: Water -- Purification -- Flocculation , Water quality management , Flocculation
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/24454 , vital:62804
- Description: The bioflocculant-producing potentials of three marine bacteria isolated from the sediment samples of Algoa Bay in the Eastern Cape Province of South Africa were assessed. Analysis of the partial nucleotide sequence of the 16S rDNA of the bacteria revealed 99 percent, 99 percent, and 98 percent similarity to Cobetia sp. L222, Bacillus sp. A-5A, and Bacillus sp. HXG-C1 respectively and the sequence was deposited in GenBank as Cobetia sp. OAUIFE, Bacillus sp. MAYA and Bacillus sp. Gilbert (accession number JF799092, JF799093, and HQ537128 respectively). Cultivation condition studies for Cobetia sp. OAUIFE revealed that bioflocculant production was optimal with an inoculum size of 2 percent (v/v), initial pH of 6.0, Mn2+ as the metal ion, and glucose as the carbon source. Metal ions, including Na+, K+, Li+, Ca2+and Mg2+ stimulated bioflocculant production resulting in flocculating activity of above 90 percent. This crude bioflocculant is thermally stable, with about 78 percent of its flocculating activity remaining after heating at 100 oC for 25 min. Analysis of the purified bioflocculant revealed it to be an acidic extracellular polysaccharide. FTIR analysis revealed the presence of methoxyl, hydroxyl, and carboxyl - groups in the compound bioflocculant and SEM micrograph of the bioflocculant revealed a crystal-linear structure. On the other hand, bioflocculant production by Bacillus sp. MAYA was optimal when glucose (95.6 percent flocculating activity) and ammonium nitrate (83.3 percent flocculating activity) were used as carbon and nitrogen sources respectively; inoculum size was 2 percent (v/v); initial pH 6; and Ca2+ as coagulant aid. Chemical analysis of the purified bioflocculant shows that it is composed of uronic acid, neutral sugar and protein. FTIR analysis also revealed the presence of methoxyl, hydroxyl, carboxyl and amino- groups in this bioflocculant. The bioflocculant is thermostable with about 65.6 percent residual flocculating activity retained after heating the bioflocculant at 100 oC for 25 min. However bioflocculant production by Bacillus sp. Gilbert was optimal when sodium carbonate (95.2 percent flocculating activity) and potassium nitrate (76.6 percent flocculating activity) were used as carbon and nitrogen sources respectively; inoculum size was 3 percent (v/v); initial pH 9; and Al3+ as cation. The crude bioflocculant retained 44.2 percent residual flocculating activity after heating at 100 oC for 15 min. FTIR analysis reveals the presence of hydroxyl, carboxyl and methylene - groups in the compound bioflocculant. SEM micrograph of the bioflocculant revealed an amorphous compound. The consortia of these bacteria strains also produced bioflocculants with high flocculating activities which were highly efficient in removing turbidity and chemical oxygen demand (COD) from brewery wastewater, diary wastewater and river water. The bioflocculants from the consortia seemed better than traditional flocculants such as alum . The characteristics of the bioflocculant produced by the consortium of Cobetia sp. OAUIFE and Bacillus sp. MAYA showed that this extracellular bioflocculant, composed of 66percent uronic acid and 31percent protein and an optimum flocculation (90 percent) of kaolin suspension, when the dosage concentration was 0.8 mg/ml, under weak alkaline pH of 8, and Ca2+ as a coagulant aid. The bioflocculant is thermally stable, with a high residual flocculating activity of 86.7 percent, 89.3 percent and 87.0 percent after heating at 50 oC, 80 oC and 100 oC for 25 min respectively. The FTIR analysis of the bioflocculant indicated the presence of hydroxyl, amino, carbonyl and carboxyl functional groups. Scanning electron microscopy (SEM) image revealed a crystal-linear spongy-like bioflocculant structure and EDX analysis of the purified bioflocculant showed that the elemental composition in mass proportion of C,N,O,S and P was 6.67:6.23:37.55:0.38:4.42 (percent w/w). However, the characteristics of the bioflocculant produced by the consortium of Cobetia sp OAUIFE and Bacillus sp. Gilbert showed an optimum flocculation (90 percent) of kaolin suspension when the dosage concentration was 0.2 mg/ml, under neutral pH of 7, and Ca2+ as a coagulant aid. The FTIR analysis of the bioflocculant indicated the presence of hydroxyl and carbonyl functional groups. Scanning electron microscopy (SEM) image revealed an amorphous morphology. On the other hand the bioflocculant produced by the consortium of Bacillus sp. MAYA and Bacillus sp. Gilbert showed similar characteristic with the bioflocculant from the consortium of Cobetia sp. OAUIFE and Bacillus sp. Gilbert except for Al3+ being the preferred coagulant aid. The characteristics of the bioflocculant produced by the consortium of Cobetia sp. OAUIFE, Bacillus sp. MAYA and Bacillus sp. Gilbert showed an optimum flocculation (87 percent) of kaolin suspension when the dosage concentration was 1.0 mg/ml. Under strong alkaline pH of 12, flocculating activity reached (95 percent) when Al3+ was the coagulant aid. The FTIR analysis of the bioflocculant indicated the presence of hydroxyl, amino, carbonyl and carboxyl and phosphoryl functional groups. Scanning electron microscopy (SEM) image revealed a flaky amorphous morphological structure. Due to the excellent COD and turbidity removal efficiencies of the bioflocculants produced by the consortia, these make those attractive candidates for use in water and wastewater treatment. , Thesis (PhD) -- Faculty of Science and Agriculture, 2013
- Full Text:
- Date Issued: 2013
- Authors: Ugbenyen, Anthony Moses https://orcid.org/0000-0002-1381-3428
- Date: 2013
- Subjects: Water -- Purification -- Flocculation , Water quality management , Flocculation
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/24454 , vital:62804
- Description: The bioflocculant-producing potentials of three marine bacteria isolated from the sediment samples of Algoa Bay in the Eastern Cape Province of South Africa were assessed. Analysis of the partial nucleotide sequence of the 16S rDNA of the bacteria revealed 99 percent, 99 percent, and 98 percent similarity to Cobetia sp. L222, Bacillus sp. A-5A, and Bacillus sp. HXG-C1 respectively and the sequence was deposited in GenBank as Cobetia sp. OAUIFE, Bacillus sp. MAYA and Bacillus sp. Gilbert (accession number JF799092, JF799093, and HQ537128 respectively). Cultivation condition studies for Cobetia sp. OAUIFE revealed that bioflocculant production was optimal with an inoculum size of 2 percent (v/v), initial pH of 6.0, Mn2+ as the metal ion, and glucose as the carbon source. Metal ions, including Na+, K+, Li+, Ca2+and Mg2+ stimulated bioflocculant production resulting in flocculating activity of above 90 percent. This crude bioflocculant is thermally stable, with about 78 percent of its flocculating activity remaining after heating at 100 oC for 25 min. Analysis of the purified bioflocculant revealed it to be an acidic extracellular polysaccharide. FTIR analysis revealed the presence of methoxyl, hydroxyl, and carboxyl - groups in the compound bioflocculant and SEM micrograph of the bioflocculant revealed a crystal-linear structure. On the other hand, bioflocculant production by Bacillus sp. MAYA was optimal when glucose (95.6 percent flocculating activity) and ammonium nitrate (83.3 percent flocculating activity) were used as carbon and nitrogen sources respectively; inoculum size was 2 percent (v/v); initial pH 6; and Ca2+ as coagulant aid. Chemical analysis of the purified bioflocculant shows that it is composed of uronic acid, neutral sugar and protein. FTIR analysis also revealed the presence of methoxyl, hydroxyl, carboxyl and amino- groups in this bioflocculant. The bioflocculant is thermostable with about 65.6 percent residual flocculating activity retained after heating the bioflocculant at 100 oC for 25 min. However bioflocculant production by Bacillus sp. Gilbert was optimal when sodium carbonate (95.2 percent flocculating activity) and potassium nitrate (76.6 percent flocculating activity) were used as carbon and nitrogen sources respectively; inoculum size was 3 percent (v/v); initial pH 9; and Al3+ as cation. The crude bioflocculant retained 44.2 percent residual flocculating activity after heating at 100 oC for 15 min. FTIR analysis reveals the presence of hydroxyl, carboxyl and methylene - groups in the compound bioflocculant. SEM micrograph of the bioflocculant revealed an amorphous compound. The consortia of these bacteria strains also produced bioflocculants with high flocculating activities which were highly efficient in removing turbidity and chemical oxygen demand (COD) from brewery wastewater, diary wastewater and river water. The bioflocculants from the consortia seemed better than traditional flocculants such as alum . The characteristics of the bioflocculant produced by the consortium of Cobetia sp. OAUIFE and Bacillus sp. MAYA showed that this extracellular bioflocculant, composed of 66percent uronic acid and 31percent protein and an optimum flocculation (90 percent) of kaolin suspension, when the dosage concentration was 0.8 mg/ml, under weak alkaline pH of 8, and Ca2+ as a coagulant aid. The bioflocculant is thermally stable, with a high residual flocculating activity of 86.7 percent, 89.3 percent and 87.0 percent after heating at 50 oC, 80 oC and 100 oC for 25 min respectively. The FTIR analysis of the bioflocculant indicated the presence of hydroxyl, amino, carbonyl and carboxyl functional groups. Scanning electron microscopy (SEM) image revealed a crystal-linear spongy-like bioflocculant structure and EDX analysis of the purified bioflocculant showed that the elemental composition in mass proportion of C,N,O,S and P was 6.67:6.23:37.55:0.38:4.42 (percent w/w). However, the characteristics of the bioflocculant produced by the consortium of Cobetia sp OAUIFE and Bacillus sp. Gilbert showed an optimum flocculation (90 percent) of kaolin suspension when the dosage concentration was 0.2 mg/ml, under neutral pH of 7, and Ca2+ as a coagulant aid. The FTIR analysis of the bioflocculant indicated the presence of hydroxyl and carbonyl functional groups. Scanning electron microscopy (SEM) image revealed an amorphous morphology. On the other hand the bioflocculant produced by the consortium of Bacillus sp. MAYA and Bacillus sp. Gilbert showed similar characteristic with the bioflocculant from the consortium of Cobetia sp. OAUIFE and Bacillus sp. Gilbert except for Al3+ being the preferred coagulant aid. The characteristics of the bioflocculant produced by the consortium of Cobetia sp. OAUIFE, Bacillus sp. MAYA and Bacillus sp. Gilbert showed an optimum flocculation (87 percent) of kaolin suspension when the dosage concentration was 1.0 mg/ml. Under strong alkaline pH of 12, flocculating activity reached (95 percent) when Al3+ was the coagulant aid. The FTIR analysis of the bioflocculant indicated the presence of hydroxyl, amino, carbonyl and carboxyl and phosphoryl functional groups. Scanning electron microscopy (SEM) image revealed a flaky amorphous morphological structure. Due to the excellent COD and turbidity removal efficiencies of the bioflocculants produced by the consortia, these make those attractive candidates for use in water and wastewater treatment. , Thesis (PhD) -- Faculty of Science and Agriculture, 2013
- Full Text:
- Date Issued: 2013
Optical limiting and femtosecond pump-probe transient absorbance properties of a 3, 5-distyrylBODIPY dye
- Ngoy, Bokolombe P, May, Aviwe K, Mack, John, Nyokong, Tebello
- Authors: Ngoy, Bokolombe P , May, Aviwe K , Mack, John , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186835 , vital:44538 , xlink:href="https://doi.org/10.3389/fchem.2019.00740"
- Description: The optical limiting (OL) properties of a 3,5-di-p-benzyloxystyrylBODIPY dye with an p-acetamidophenyl moiety at the meso-position have been investigated by using the open-aperture Z-scan technique at 532 nm with 10 ns laser pulses. There is a ca. 140 nm red shift of the main spectral band to 644 nm relative to the corresponding BODIPY core dye, due to the incorporation of p-benzyloxystyryl groups at the 3,5-positions. As a result, there is relatively weak absorbance across most of the visible region under ambient light conditions. Analysis of the observed reverse saturable absorbance (RSA) profiles demonstrates that the dye is potentially suitable for use in optical limiting applications as has been reported previously for other 3,5-distyrylBODIPY dyes. Time-resolved transient absorption spectroscopy and kinetic studies with femtosecond and nanosecond scale laser pulses provide the first direct spectral evidence that excited state absorption (ESA) from the S1 state is responsible for the observed OL properties.
- Full Text:
- Date Issued: 2019
- Authors: Ngoy, Bokolombe P , May, Aviwe K , Mack, John , Nyokong, Tebello
- Date: 2019
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186835 , vital:44538 , xlink:href="https://doi.org/10.3389/fchem.2019.00740"
- Description: The optical limiting (OL) properties of a 3,5-di-p-benzyloxystyrylBODIPY dye with an p-acetamidophenyl moiety at the meso-position have been investigated by using the open-aperture Z-scan technique at 532 nm with 10 ns laser pulses. There is a ca. 140 nm red shift of the main spectral band to 644 nm relative to the corresponding BODIPY core dye, due to the incorporation of p-benzyloxystyryl groups at the 3,5-positions. As a result, there is relatively weak absorbance across most of the visible region under ambient light conditions. Analysis of the observed reverse saturable absorbance (RSA) profiles demonstrates that the dye is potentially suitable for use in optical limiting applications as has been reported previously for other 3,5-distyrylBODIPY dyes. Time-resolved transient absorption spectroscopy and kinetic studies with femtosecond and nanosecond scale laser pulses provide the first direct spectral evidence that excited state absorption (ESA) from the S1 state is responsible for the observed OL properties.
- Full Text:
- Date Issued: 2019
Capital flows and real exchange rate movement in South Africa
- Authors: Lindani, Sandiswa
- Date: 2021-09
- Subjects: Foreign exchange rates , Exchange rate pass-through , Capital movements
- Language: English
- Type: Master's/ theses , text
- Identifier: http://hdl.handle.net/10353/20417 , vital:45664
- Description: The neoclassical theory suggests that free flow of external capital should be equilibrating and thereby facilitating smoothening of an economy's consumption or production patterns. Based on this background, this study empirically examines the extent to which the different forms of capital flows amongst other variables influence the real exchange rate in South Africa for the period 1980 to 2019, using annual data. Estimation techniques employed include the Johansen Co-integration Approach and the Vector error correction model (VECM). The variables were found to be co-integrated, with six co-integrating vectors existing. The long-run results revealed that FPI has an appreciating effect on the exchange rate in South Africa. Based on the results, policy recommendations are suggested. , Thesis (MCom) (Economics) -- University of Fort Hare, 2021.
- Full Text:
- Date Issued: 2021-09
- Authors: Lindani, Sandiswa
- Date: 2021-09
- Subjects: Foreign exchange rates , Exchange rate pass-through , Capital movements
- Language: English
- Type: Master's/ theses , text
- Identifier: http://hdl.handle.net/10353/20417 , vital:45664
- Description: The neoclassical theory suggests that free flow of external capital should be equilibrating and thereby facilitating smoothening of an economy's consumption or production patterns. Based on this background, this study empirically examines the extent to which the different forms of capital flows amongst other variables influence the real exchange rate in South Africa for the period 1980 to 2019, using annual data. Estimation techniques employed include the Johansen Co-integration Approach and the Vector error correction model (VECM). The variables were found to be co-integrated, with six co-integrating vectors existing. The long-run results revealed that FPI has an appreciating effect on the exchange rate in South Africa. Based on the results, policy recommendations are suggested. , Thesis (MCom) (Economics) -- University of Fort Hare, 2021.
- Full Text:
- Date Issued: 2021-09
An investigation of support services available for black female owners of bed & breakfasts in Makhanda
- Authors: Mdluli, Lukhona Silubonile
- Date: 2021-04
- Subjects: Bed and breakfast accommodations -- South Africa -- Makhanda , Businesspeople, Black -- South Africa -- Makhanda , Business enterprises, Black -- South Africa -- Makhanda , Women-owned business enterprises -- South Africa -- Makhanda , Government aid to small business -- South Africa , Small business -- South Africa -- Makhanda , Racism -- South Africa -- Makhanda , Businesswomen -- South Africa -- Makhanda
- Language: English
- Type: thesis , text , Masters , MBA
- Identifier: http://hdl.handle.net/10962/177181 , vital:42797
- Description: Over the last 26 years, the South African government has committed to SMME development. To do this, policies and support institutions were put in place which would create a favourable environment for SMME development. This was particularly important as after 1994, when the South African economy was re-integrated into global markets after years of having sanctions imposed against the country as a result of the apartheid system. The tourism industry was identified as one of the key economic drivers which would strengthen the economy and assist in job creation, especially since South Africa would be able to attract international tourists. Further, it created the opportunity for new participants to enter the industry, including black entrepreneurs who previously could not enter the industry as a result of the apartheid laws. The opening up of the country to international markets and the focus on the tourism industry also presented the opportunity for new forms of tourism to be explored including township tourism, which gave rise to the black-owned bed & breakfast sector. Over time, it has become evident that black entrepreneurs in this sector are facing a number of challenges, in spite of the pro-SMME policies and support institutions that are in place. Because this study seeks to investigate the support services available for black female bed & breakfast owners in Makhanda, a qualitative research approach using the interpretative theoretical framework was applied. By using semi-structured interview questions, to establish what challenges do black female bed and breakfast owners face the researcher was able to respond to the following; what participants identify as their needs; and whether they are able to access the support services that are made available by the Government. Results indicated that the majority of entrepreneurs have difficulty accessing funding to develop their businesses. The seasonality of Grahamstown/ Makhanda tourism businesses has its pros and cons for tourism entrepreneurs. Despite efforts by government to transform the tourism industry, black female entrepreneurs in this industry still experience a myriad of challenges, including passive racism. Insufficient institutional support and inaccessible support services for women have made it difficult to manage in this this environment. Thus, a recommendation is put forward for female focused entrepreneurship policy, which is more responsive in terms of a judicial and legal system(s) aimed at addressing women’s particular needs and challenges. , Thesis (MBA) -- Faculty of Commerce, Rhodes Business School, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Mdluli, Lukhona Silubonile
- Date: 2021-04
- Subjects: Bed and breakfast accommodations -- South Africa -- Makhanda , Businesspeople, Black -- South Africa -- Makhanda , Business enterprises, Black -- South Africa -- Makhanda , Women-owned business enterprises -- South Africa -- Makhanda , Government aid to small business -- South Africa , Small business -- South Africa -- Makhanda , Racism -- South Africa -- Makhanda , Businesswomen -- South Africa -- Makhanda
- Language: English
- Type: thesis , text , Masters , MBA
- Identifier: http://hdl.handle.net/10962/177181 , vital:42797
- Description: Over the last 26 years, the South African government has committed to SMME development. To do this, policies and support institutions were put in place which would create a favourable environment for SMME development. This was particularly important as after 1994, when the South African economy was re-integrated into global markets after years of having sanctions imposed against the country as a result of the apartheid system. The tourism industry was identified as one of the key economic drivers which would strengthen the economy and assist in job creation, especially since South Africa would be able to attract international tourists. Further, it created the opportunity for new participants to enter the industry, including black entrepreneurs who previously could not enter the industry as a result of the apartheid laws. The opening up of the country to international markets and the focus on the tourism industry also presented the opportunity for new forms of tourism to be explored including township tourism, which gave rise to the black-owned bed & breakfast sector. Over time, it has become evident that black entrepreneurs in this sector are facing a number of challenges, in spite of the pro-SMME policies and support institutions that are in place. Because this study seeks to investigate the support services available for black female bed & breakfast owners in Makhanda, a qualitative research approach using the interpretative theoretical framework was applied. By using semi-structured interview questions, to establish what challenges do black female bed and breakfast owners face the researcher was able to respond to the following; what participants identify as their needs; and whether they are able to access the support services that are made available by the Government. Results indicated that the majority of entrepreneurs have difficulty accessing funding to develop their businesses. The seasonality of Grahamstown/ Makhanda tourism businesses has its pros and cons for tourism entrepreneurs. Despite efforts by government to transform the tourism industry, black female entrepreneurs in this industry still experience a myriad of challenges, including passive racism. Insufficient institutional support and inaccessible support services for women have made it difficult to manage in this this environment. Thus, a recommendation is put forward for female focused entrepreneurship policy, which is more responsive in terms of a judicial and legal system(s) aimed at addressing women’s particular needs and challenges. , Thesis (MBA) -- Faculty of Commerce, Rhodes Business School, 2021
- Full Text:
- Date Issued: 2021-04
Exploring the potential of developmental work research and change laboratory to support sustainability transformations: a case study of organic agriculture in Zimbabwe
- Mukute, Mutizwa, Mudokwani, Kuda, McAllistair, Georgina, Nyikahadzoi, Kefasi
- Authors: Mukute, Mutizwa , Mudokwani, Kuda , McAllistair, Georgina , Nyikahadzoi, Kefasi
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/392119 , vital:68723 , xlink:href="https://doi.org/10.1080/10749039.2018.1451542"
- Description: This paper explores the emergence of transgressive learning in CHAT-informed development work research in a networked organic agriculture case study in Zimbabwe, based on intervention research involving district organic associations tackling interconnected issues of climate change, water, food security and solidarity. The study established that We change laboratories can be used to support transgressive learning through: confronting unproductive local norms; collective reframing of problematic issues; stimulating expansive learning and sustainability transformations in minds, relationships and landscapes across time. The study also confirms the need for fourth generation CHAT to address the complex social-ecological problems of today.
- Full Text:
- Date Issued: 2018
- Authors: Mukute, Mutizwa , Mudokwani, Kuda , McAllistair, Georgina , Nyikahadzoi, Kefasi
- Date: 2018
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/392119 , vital:68723 , xlink:href="https://doi.org/10.1080/10749039.2018.1451542"
- Description: This paper explores the emergence of transgressive learning in CHAT-informed development work research in a networked organic agriculture case study in Zimbabwe, based on intervention research involving district organic associations tackling interconnected issues of climate change, water, food security and solidarity. The study established that We change laboratories can be used to support transgressive learning through: confronting unproductive local norms; collective reframing of problematic issues; stimulating expansive learning and sustainability transformations in minds, relationships and landscapes across time. The study also confirms the need for fourth generation CHAT to address the complex social-ecological problems of today.
- Full Text:
- Date Issued: 2018
The photophysical properties of multi-functional quantum dots-magnetic nanoparticles—indium octacarboxyphthalocyanine nanocomposite
- Tshangana, Charmaine, Nyokong, Tebello
- Authors: Tshangana, Charmaine , Nyokong, Tebello
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189876 , vital:44942 , xlink:href="https://doi.org/10.1007/s10895-014-1497-6"
- Description: This work presents the development of a multifunctional hybrid nanoparticle made of L-glutathione capped quantum dots (GSH-CdSe@ZnS), amino functionalized Fe3O4 magnetic nanoparticles and indium octacarboxy phthalocyanine (ClInPc(COOH)8). In this work we investigate the photophysical properties of the individual components and the hybrid nanoparticle, in addition we study the energy transfer (Förster Resonance Energy Transfer (FRET)) in the complex. FRET efficiencies of ~48 % were obtained for energy transfer between the QDs (when alone or linked to MNPs). Both triplet yields and lifetimes of ClInPc(COOH)8 increase in the nanocomposite, with a decrease in fluorescence lifetime. The hybrid nanoparticle showed improved photophysical properties and as a result can be used in photodynamic therapy.
- Full Text:
- Date Issued: 2015
- Authors: Tshangana, Charmaine , Nyokong, Tebello
- Date: 2015
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/189876 , vital:44942 , xlink:href="https://doi.org/10.1007/s10895-014-1497-6"
- Description: This work presents the development of a multifunctional hybrid nanoparticle made of L-glutathione capped quantum dots (GSH-CdSe@ZnS), amino functionalized Fe3O4 magnetic nanoparticles and indium octacarboxy phthalocyanine (ClInPc(COOH)8). In this work we investigate the photophysical properties of the individual components and the hybrid nanoparticle, in addition we study the energy transfer (Förster Resonance Energy Transfer (FRET)) in the complex. FRET efficiencies of ~48 % were obtained for energy transfer between the QDs (when alone or linked to MNPs). Both triplet yields and lifetimes of ClInPc(COOH)8 increase in the nanocomposite, with a decrease in fluorescence lifetime. The hybrid nanoparticle showed improved photophysical properties and as a result can be used in photodynamic therapy.
- Full Text:
- Date Issued: 2015
Sources of advertisement messages and their impacts on purchasing behaviour:A case study of Walter Sisulu University students
- Oladimeji, Olawumi Kate https://orcid.org/0000-0002-6577-0140
- Authors: Oladimeji, Olawumi Kate https://orcid.org/0000-0002-6577-0140
- Date: 2013-11
- Subjects: Mass Media -- Social Aspect , Advertising -- Social Aspects
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23203 , vital:55898
- Description: The purpose of this research was to investigate the sources of advertisement messages and the impacts they have on the buying behaviour of students of Walter Sisulu University (WSU) and examine whether traditional mass media advertising still influences the students’ decision to buy and whether advancement in communication technology affects how the students receive information. This study also investigated the impact of traditional mass media advertising in comparison to new media advertising. Questionnaires were administered to students of WSU, Mthatha campus. The survey was conducted within the period of February 2013 – March 2013. The desired sample size was 270 students. A final sample of 220 valid responses was analysed, representing 81 percent of the desired sample. The study revealed that majority are aware of television while billboards and direct mails have the least awareness. The results also revealed that 78 percent of the respondents felt that traditional mass media still influences their buying behaviour, (90 percent) of the respondents prefer the traditional mass media advertising. This study demonstrated that the students of WSU are aware and exposed to the various sources of advertisement messages. In addition, existing literature and this research report have shown that the various mediums have distinctive characteristics which make them unique. In spite of the advent of modern technology, the traditional mass media still influences buying behaviour with television being the most influential media. , Thesis (MA) -- Faculty of Social Sciences and Humanities, 2013
- Full Text:
- Date Issued: 2013-11
- Authors: Oladimeji, Olawumi Kate https://orcid.org/0000-0002-6577-0140
- Date: 2013-11
- Subjects: Mass Media -- Social Aspect , Advertising -- Social Aspects
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/23203 , vital:55898
- Description: The purpose of this research was to investigate the sources of advertisement messages and the impacts they have on the buying behaviour of students of Walter Sisulu University (WSU) and examine whether traditional mass media advertising still influences the students’ decision to buy and whether advancement in communication technology affects how the students receive information. This study also investigated the impact of traditional mass media advertising in comparison to new media advertising. Questionnaires were administered to students of WSU, Mthatha campus. The survey was conducted within the period of February 2013 – March 2013. The desired sample size was 270 students. A final sample of 220 valid responses was analysed, representing 81 percent of the desired sample. The study revealed that majority are aware of television while billboards and direct mails have the least awareness. The results also revealed that 78 percent of the respondents felt that traditional mass media still influences their buying behaviour, (90 percent) of the respondents prefer the traditional mass media advertising. This study demonstrated that the students of WSU are aware and exposed to the various sources of advertisement messages. In addition, existing literature and this research report have shown that the various mediums have distinctive characteristics which make them unique. In spite of the advent of modern technology, the traditional mass media still influences buying behaviour with television being the most influential media. , Thesis (MA) -- Faculty of Social Sciences and Humanities, 2013
- Full Text:
- Date Issued: 2013-11
Applying insights from machine learning towards guidelines for the detection of text-based fake news
- Authors: Ngada, Okuhle
- Date: 2021-12
- Subjects: Machine learning , Fake News
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/60243 , vital:64141
- Description: Web-based technologies have fostered an online environment where information can be disseminated in a fast and cost-effective manner whilst targeting large and diverse audiences. Unfortunately, the rise and evolution of web-based technologies have also created an environment where false information, commonly referred to as “fake news”, spreads rapidly. The effects of this spread can be catastrophic. Finding solutions to the problem of fake news is complicated for a myriad of reasons, such as: what is defined as fake news, the lack of quality datasets available to researchers, the topics covered in such data, and the fact that datasets exist in a variety of languages. The effects of false information dissemination can result in reputational damage, financial damage to affected brands, and ultimately, misinformed online news readers who can make misinformed decisions. The objective of the study is to propose a set of guidelines that can be used by other system developers to implement misinformation detection tools and systems. The guidelines are constructed using findings from the experimentation phase of the project and information uncovered in the literature review conducted as part of the study. A selection of machine and deep learning approaches are examined to test the applicability of cues that could separate fake online articles from real online news articles. Key performance metrics such as precision, recall, accuracy, F1-score, and ROC are used to measure the performance of the selected machine learning and deep learning models. To demonstrate the practicality of the guidelines and allow for reproducibility of the research, each guideline provides background information relating to the identified problem, a solution to the problem through pseudocode, code excerpts using the Python programming language, and points of consideration that may assist with the implementation. , Thesis (MA) --Faculty of Engineering, the Built Environment, and Technology, 2021
- Full Text:
- Date Issued: 2021-12
Applying insights from machine learning towards guidelines for the detection of text-based fake news
- Authors: Ngada, Okuhle
- Date: 2021-12
- Subjects: Machine learning , Fake News
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/60243 , vital:64141
- Description: Web-based technologies have fostered an online environment where information can be disseminated in a fast and cost-effective manner whilst targeting large and diverse audiences. Unfortunately, the rise and evolution of web-based technologies have also created an environment where false information, commonly referred to as “fake news”, spreads rapidly. The effects of this spread can be catastrophic. Finding solutions to the problem of fake news is complicated for a myriad of reasons, such as: what is defined as fake news, the lack of quality datasets available to researchers, the topics covered in such data, and the fact that datasets exist in a variety of languages. The effects of false information dissemination can result in reputational damage, financial damage to affected brands, and ultimately, misinformed online news readers who can make misinformed decisions. The objective of the study is to propose a set of guidelines that can be used by other system developers to implement misinformation detection tools and systems. The guidelines are constructed using findings from the experimentation phase of the project and information uncovered in the literature review conducted as part of the study. A selection of machine and deep learning approaches are examined to test the applicability of cues that could separate fake online articles from real online news articles. Key performance metrics such as precision, recall, accuracy, F1-score, and ROC are used to measure the performance of the selected machine learning and deep learning models. To demonstrate the practicality of the guidelines and allow for reproducibility of the research, each guideline provides background information relating to the identified problem, a solution to the problem through pseudocode, code excerpts using the Python programming language, and points of consideration that may assist with the implementation. , Thesis (MA) --Faculty of Engineering, the Built Environment, and Technology, 2021
- Full Text:
- Date Issued: 2021-12