Simplified menu-driven data analysis tool with macro-like automation
- Authors: Kazembe, Luntha
- Date: 2022-10-14
- Subjects: Data analysis , Macro instructions (Electronic computers) , Quantitative research Software , Python (Computer program language) , Scripting languages (Computer science)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/362905 , vital:65373
- Description: This study seeks to improve the data analysis process for individuals and small businesses with limited resources by developing a simplified data analysis software tool that allows users to carry out data analysis effectively and efficiently. Design considerations were identified to address limitations common in such environments, these included making the tool easy-to-use, requiring only a basic understanding of the data analysis process, designing the tool in manner that minimises computing resource requirements and user interaction and implementing it using Python which is open-source, effective and efficient in processing data. We develop a prototype simplified data analysis tool as a proof-of-concept. The tool has two components, namely, core elements which provide functionality for the data anal- ysis process including data collection, transformations, analysis and visualizations, and automation and performance enhancements to improve the data analysis process. The automation enhancements consist of the record and playback macro feature while the performance enhancements include multiprocessing and multi-threading abilities. The data analysis software was developed to analyse various alpha-numeric data formats by using a variety of statistical and mathematical techniques. The record and playback macro feature enhances the data analysis process by saving users time and computing resources when analysing large volumes of data or carrying out repetitive data analysis tasks. The feature has two components namely, the record component that is used to record data analysis steps and the playback component used to execute recorded steps. The simplified data analysis tool has parallelization designed and implemented which allows users to carry out two or more analysis tasks at a time, this improves productivity as users can do other tasks while the tool is processing data using recorded steps in the background. The tool was created and subsequently tested using common analysis scenarios applied to network data, log data and stock data. Results show that decision-making requirements such as accurate information, can be satisfied using this analysis tool. Based on the functionality implemented, similar analysis functionality to that provided by Microsoft Excel is available, but in a simplified manner. Moreover, a more sophisticated macro functionality is provided for the execution of repetitive tasks using the recording feature. Overall, the study found that the simplified data analysis tool is functional, usable, scalable, efficient and can carry out multiple analysis tasks simultaneously. , Thesis (MSc) -- Faculty of Science, Computer Science, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Kazembe, Luntha
- Date: 2022-10-14
- Subjects: Data analysis , Macro instructions (Electronic computers) , Quantitative research Software , Python (Computer program language) , Scripting languages (Computer science)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/362905 , vital:65373
- Description: This study seeks to improve the data analysis process for individuals and small businesses with limited resources by developing a simplified data analysis software tool that allows users to carry out data analysis effectively and efficiently. Design considerations were identified to address limitations common in such environments, these included making the tool easy-to-use, requiring only a basic understanding of the data analysis process, designing the tool in manner that minimises computing resource requirements and user interaction and implementing it using Python which is open-source, effective and efficient in processing data. We develop a prototype simplified data analysis tool as a proof-of-concept. The tool has two components, namely, core elements which provide functionality for the data anal- ysis process including data collection, transformations, analysis and visualizations, and automation and performance enhancements to improve the data analysis process. The automation enhancements consist of the record and playback macro feature while the performance enhancements include multiprocessing and multi-threading abilities. The data analysis software was developed to analyse various alpha-numeric data formats by using a variety of statistical and mathematical techniques. The record and playback macro feature enhances the data analysis process by saving users time and computing resources when analysing large volumes of data or carrying out repetitive data analysis tasks. The feature has two components namely, the record component that is used to record data analysis steps and the playback component used to execute recorded steps. The simplified data analysis tool has parallelization designed and implemented which allows users to carry out two or more analysis tasks at a time, this improves productivity as users can do other tasks while the tool is processing data using recorded steps in the background. The tool was created and subsequently tested using common analysis scenarios applied to network data, log data and stock data. Results show that decision-making requirements such as accurate information, can be satisfied using this analysis tool. Based on the functionality implemented, similar analysis functionality to that provided by Microsoft Excel is available, but in a simplified manner. Moreover, a more sophisticated macro functionality is provided for the execution of repetitive tasks using the recording feature. Overall, the study found that the simplified data analysis tool is functional, usable, scalable, efficient and can carry out multiple analysis tasks simultaneously. , Thesis (MSc) -- Faculty of Science, Computer Science, 2022
- Full Text:
- Date Issued: 2022-10-14
A sea is brewing
- Authors: Mama, Sibongakonke
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Xhosa poetry 21st century , South African poetry (English) 21st century , Psychic trauma in literature , Women in literature , Diaries -- Authorship , Books Reviews
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406281 , vital:70255
- Description: My thesis is a collection of poems that draws on the complexity of not belonging in places, with people, or within families. I engage my own alienation as well as that of my parents, black people generally, and women in particular. I take inspiration from Uruguayan poet Fabián Severo’s autobiographical long poem, Night in the North, which chronicles the poet’s experience of growing up in linguistic and cultural borderlands. I am also influenced by Chilean poet Carmen García’s ability to move between the concrete and the abstract in translations of her poems from the collection Gotas sobre loza fría. As much as my poems traverse a metaphysical space, they are also set in concrete places – Tutura, Gcuwa, Johannesburg, and Cape Town. Like Chilean artist Cecilia Vicuña’s Spit Temple, I move between the physical and spiritual realms for a better understanding of my estrangement. I also draw on South African poet Mangaliso Buzani’s book, a naked bone, for its fluid combination of line and prose poetry. I write in isiXhosa and English as a reflection of my mixed cultural and linguistic existence. I seek to harness rhythm and harmony, as well as the quiet, between words. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Mama, Sibongakonke
- Date: 2022-10-14
- Subjects: Creative writing (Higher education) South Africa , Xhosa poetry 21st century , South African poetry (English) 21st century , Psychic trauma in literature , Women in literature , Diaries -- Authorship , Books Reviews
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406281 , vital:70255
- Description: My thesis is a collection of poems that draws on the complexity of not belonging in places, with people, or within families. I engage my own alienation as well as that of my parents, black people generally, and women in particular. I take inspiration from Uruguayan poet Fabián Severo’s autobiographical long poem, Night in the North, which chronicles the poet’s experience of growing up in linguistic and cultural borderlands. I am also influenced by Chilean poet Carmen García’s ability to move between the concrete and the abstract in translations of her poems from the collection Gotas sobre loza fría. As much as my poems traverse a metaphysical space, they are also set in concrete places – Tutura, Gcuwa, Johannesburg, and Cape Town. Like Chilean artist Cecilia Vicuña’s Spit Temple, I move between the physical and spiritual realms for a better understanding of my estrangement. I also draw on South African poet Mangaliso Buzani’s book, a naked bone, for its fluid combination of line and prose poetry. I write in isiXhosa and English as a reflection of my mixed cultural and linguistic existence. I seek to harness rhythm and harmony, as well as the quiet, between words. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2022
- Full Text:
- Date Issued: 2022-10-14
A self-emulsifying delivery system loaded with efavirenz: The case for flax-seed oil
- Authors: Mazonde, Priveledge
- Date: 2021-10-29
- Subjects: Drug delivery systems , Linseed oil , Antiretroviral agents , HIV (Viruses) , Drug carriers (Pharmacy) , Solubility , High performance liquid chromatography , Efavirenz
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192944 , vital:45283
- Description: The feasibility of incorporating efavirenz (EFV), an antiretroviral agent against HIV into a lipid-based self-emulsifying drug delivery system (SEDDS) containing vegetable oils was investigated. EFV has poor aqueous solubility and is classified under the Biopharmaceutical Classification System (BCS) as a class II compound with highly permeability, its aqueous solubility is less than 10 mg/ml and is defined as a practically insoluble compound with a consequent poor bioavailability of approximately 40%, and erratic dissolution behaviour. SEDDS formulations have been shown to improve the aqueous solubility and consequently the bioavailability of BCS II compounds such as EFV. EFV is a first line antiviral agent used in combination with other agents in antiretroviral therapy (ART). Among the number of NNRTIs approved for use in HIV treatment, EFV is one of the most commonly prescribed drug. Statistical methods and Design of Experiments (DoE) using Response Surface Methodology (RSM), specifically a Central Composite Design (CCD), were used to facilitate the development of a reversed-phase high performance liquid chromatographic (HPLC) method for the quantitation of EFV during formulation product and process development studies. A rapid, accurate, precise and sensitive HPLC method with ultraviolet (UV) detection was developed, optimised and validated for the in-vitro analysis of EFV in a total run time under 10 minutes for the elution of both EFV and loratidine which was used as the internal standard (IS). The method was then successfully applied to the determination of EFV in commercially available tablets. Excipient screening was undertaken using solubility studies and revealed that EFV had highest solubility in flaxseed oil in comparison to soybean, macadamia, grapeseed, sunflower and olive oils. The non-ionic Tween® 80 and Span® 20 were selected as surfactant and co-surfactant, respectively with ethanol co-solvent as they exhibited improved miscibility with co-solvent. Pre-formulation studies were undertaken to investigate the compatibility of the API with excipients and to identify a nano-emulsion region and other emulsion types using pseudoternary phase diagrams. The phase behaviour of crude cold pressed flaxseed oil with the selected non-ionic surfactants revealed an area within pseudo-ternary phase diagrams for different surfactant-mixtures formed gels/semisolid structures which can be exploited for other drug delivery strategies that require such properties. Fourier transform infrared spectroscopy (FT-IR), powder x-ray diffraction (XRD) and Raman spectroscopy were used to identify and assess the compatibility of EFV with chosen excipients. 2 A reduction in the peak intensity was observed for EFV when combined with each hydrophobic/lipid excipient evaluated revealing that there was a marked reduction in the crystallinity of the EFV. A decrease in crystallinity in comparison with the bulk API may indicate that EFV were amorphous or sequestered in a molecular dispersion and exhibited an increased solubility for the molecule. Flaxseed oil was used as the oil phase in studies for the optimization of surfactant mixtures undertaken using DoE, specifically a D-optimal mixtures design with the flaxseed oil content set at 10% m/m was performed. Solutions from the desired optimization function were produced based on desirability and five nanoemulsion formulations were produced and characterized in terms of in vitro release of efavirenz, drug loading capacity, Zeta Potential, droplet sizes and polydispersity index (PDI). Kinetically stable nanoemulsions containing 10% m/m flaxseed oil were successfully manufactured and assessed. Droplet sizes ranged between 156 and 225 nm, Zeta Potential between −24 and −41 mV and all formulations were found to be monodisperse with polydispersity indices ≤ 0.487. SEDDS formulations of EFV in nano-sized carriers were developed and optimised, in vitro drug release varied with varying amounts of ethanol in the formulation producing formulations that exhibited differently modulated drug in-vitro release profiles that may be further manipulated for better performance and therapeutic outcomes in terms of solubility and possibly bioavailability of EFV when delivered using SEDDS rather than using tablets which in turn may lead to better therapeutic outcomes for patients with HIV. , Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Mazonde, Priveledge
- Date: 2021-10-29
- Subjects: Drug delivery systems , Linseed oil , Antiretroviral agents , HIV (Viruses) , Drug carriers (Pharmacy) , Solubility , High performance liquid chromatography , Efavirenz
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192944 , vital:45283
- Description: The feasibility of incorporating efavirenz (EFV), an antiretroviral agent against HIV into a lipid-based self-emulsifying drug delivery system (SEDDS) containing vegetable oils was investigated. EFV has poor aqueous solubility and is classified under the Biopharmaceutical Classification System (BCS) as a class II compound with highly permeability, its aqueous solubility is less than 10 mg/ml and is defined as a practically insoluble compound with a consequent poor bioavailability of approximately 40%, and erratic dissolution behaviour. SEDDS formulations have been shown to improve the aqueous solubility and consequently the bioavailability of BCS II compounds such as EFV. EFV is a first line antiviral agent used in combination with other agents in antiretroviral therapy (ART). Among the number of NNRTIs approved for use in HIV treatment, EFV is one of the most commonly prescribed drug. Statistical methods and Design of Experiments (DoE) using Response Surface Methodology (RSM), specifically a Central Composite Design (CCD), were used to facilitate the development of a reversed-phase high performance liquid chromatographic (HPLC) method for the quantitation of EFV during formulation product and process development studies. A rapid, accurate, precise and sensitive HPLC method with ultraviolet (UV) detection was developed, optimised and validated for the in-vitro analysis of EFV in a total run time under 10 minutes for the elution of both EFV and loratidine which was used as the internal standard (IS). The method was then successfully applied to the determination of EFV in commercially available tablets. Excipient screening was undertaken using solubility studies and revealed that EFV had highest solubility in flaxseed oil in comparison to soybean, macadamia, grapeseed, sunflower and olive oils. The non-ionic Tween® 80 and Span® 20 were selected as surfactant and co-surfactant, respectively with ethanol co-solvent as they exhibited improved miscibility with co-solvent. Pre-formulation studies were undertaken to investigate the compatibility of the API with excipients and to identify a nano-emulsion region and other emulsion types using pseudoternary phase diagrams. The phase behaviour of crude cold pressed flaxseed oil with the selected non-ionic surfactants revealed an area within pseudo-ternary phase diagrams for different surfactant-mixtures formed gels/semisolid structures which can be exploited for other drug delivery strategies that require such properties. Fourier transform infrared spectroscopy (FT-IR), powder x-ray diffraction (XRD) and Raman spectroscopy were used to identify and assess the compatibility of EFV with chosen excipients. 2 A reduction in the peak intensity was observed for EFV when combined with each hydrophobic/lipid excipient evaluated revealing that there was a marked reduction in the crystallinity of the EFV. A decrease in crystallinity in comparison with the bulk API may indicate that EFV were amorphous or sequestered in a molecular dispersion and exhibited an increased solubility for the molecule. Flaxseed oil was used as the oil phase in studies for the optimization of surfactant mixtures undertaken using DoE, specifically a D-optimal mixtures design with the flaxseed oil content set at 10% m/m was performed. Solutions from the desired optimization function were produced based on desirability and five nanoemulsion formulations were produced and characterized in terms of in vitro release of efavirenz, drug loading capacity, Zeta Potential, droplet sizes and polydispersity index (PDI). Kinetically stable nanoemulsions containing 10% m/m flaxseed oil were successfully manufactured and assessed. Droplet sizes ranged between 156 and 225 nm, Zeta Potential between −24 and −41 mV and all formulations were found to be monodisperse with polydispersity indices ≤ 0.487. SEDDS formulations of EFV in nano-sized carriers were developed and optimised, in vitro drug release varied with varying amounts of ethanol in the formulation producing formulations that exhibited differently modulated drug in-vitro release profiles that may be further manipulated for better performance and therapeutic outcomes in terms of solubility and possibly bioavailability of EFV when delivered using SEDDS rather than using tablets which in turn may lead to better therapeutic outcomes for patients with HIV. , Thesis (MSc) -- Faculty of Pharmacy, Pharmacy, 2021
- Full Text:
- Date Issued: 2021-10-29
Antimalarial activity of quinoline thiosemicarbazones: synthesis and antiplasmodial evaluation
- Nqeno, Lukhanyiso Khanyisile
- Authors: Nqeno, Lukhanyiso Khanyisile
- Date: 2022-04-06
- Subjects: Antimalarials , Quinoline , Thiosemicarbazones , Malaria Chemotherapy , Plasmodium falciparum , Malaria Africa, Sub-Saharan , Iron chelates Therapeutic use
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/291292 , vital:56841
- Description: Africa is one of the regions that is most affected by malaria, as 90% of all malaria deaths occur in sub-saharan Africa. Malaria is a life threatening disease responsible for an estimated 800000 deaths each year, the majority of these deaths occurred in children under the age of five. The disease is a mosquito-borne, and it is transmitted to humans by the female Anopheles mosquito. The parasite responsible for this disease belong to the Plasmodium genus with Plasmodium falciparum causing the most severe cases of the disease in humans. The most widely available anti-malarials were designed to specifically target the pathogenic blood stage in humans, however, in order to completely eradicate malaria there is a need for the development of medicines that not only target the pathogenic blood stage of the parasite but also block parasite transmission and eliminate asymptomatic and cryptic hepatic forms of the parasite. Iron chelators have recently gained importance as potent antimalarials, to cause infection nearly all protozoa obtain growth essential iron from their hosts. Iron is required for the development of the parasite. Deprivation of utilizable iron by chelation is a proficient approach to arrest parasite growth and associated infection. Thiosemicarbazones are known iron chelating agents by bonding through the sulfur and azomethine nitrogen atoms. This study is aimed at the identification of thiosemicarbazone based derivatives as possible antimalarial agents. Due to their iron chelation abilities there has been increasing interest in the investigation of thiosemicarbazones as possible antimalarials. During the course of this project, several thiosemicarbazone derivatives were synthesized and their structure confirmed using routine analytical techniques (NMR, FTIR, and HRMS). The synthesized compounds were evaluated in vitro against the chloroquine sensitive strain (3D7) of P. falciparum for antimarial activity. The compounds were also evaluated agsinst Hela cells for overt cytotoxicity. The compounds generally showed poor antimalarial activity. One compound (LKN11) was identified to possess intrinsic and moderate antimalarial activity of 6.6 μM. The compounds were generally not cytotoxic against Hela cell at concentrations of up to 20 μM, with only compound LKN10 showing modest cytotoxic activity of 9.5 μM. This research went on to identify two thiosemicarbazone based derivatives which had a significant effect on HeLa and pLDH cells. , Thesis (MSc) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Nqeno, Lukhanyiso Khanyisile
- Date: 2022-04-06
- Subjects: Antimalarials , Quinoline , Thiosemicarbazones , Malaria Chemotherapy , Plasmodium falciparum , Malaria Africa, Sub-Saharan , Iron chelates Therapeutic use
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/291292 , vital:56841
- Description: Africa is one of the regions that is most affected by malaria, as 90% of all malaria deaths occur in sub-saharan Africa. Malaria is a life threatening disease responsible for an estimated 800000 deaths each year, the majority of these deaths occurred in children under the age of five. The disease is a mosquito-borne, and it is transmitted to humans by the female Anopheles mosquito. The parasite responsible for this disease belong to the Plasmodium genus with Plasmodium falciparum causing the most severe cases of the disease in humans. The most widely available anti-malarials were designed to specifically target the pathogenic blood stage in humans, however, in order to completely eradicate malaria there is a need for the development of medicines that not only target the pathogenic blood stage of the parasite but also block parasite transmission and eliminate asymptomatic and cryptic hepatic forms of the parasite. Iron chelators have recently gained importance as potent antimalarials, to cause infection nearly all protozoa obtain growth essential iron from their hosts. Iron is required for the development of the parasite. Deprivation of utilizable iron by chelation is a proficient approach to arrest parasite growth and associated infection. Thiosemicarbazones are known iron chelating agents by bonding through the sulfur and azomethine nitrogen atoms. This study is aimed at the identification of thiosemicarbazone based derivatives as possible antimalarial agents. Due to their iron chelation abilities there has been increasing interest in the investigation of thiosemicarbazones as possible antimalarials. During the course of this project, several thiosemicarbazone derivatives were synthesized and their structure confirmed using routine analytical techniques (NMR, FTIR, and HRMS). The synthesized compounds were evaluated in vitro against the chloroquine sensitive strain (3D7) of P. falciparum for antimarial activity. The compounds were also evaluated agsinst Hela cells for overt cytotoxicity. The compounds generally showed poor antimalarial activity. One compound (LKN11) was identified to possess intrinsic and moderate antimalarial activity of 6.6 μM. The compounds were generally not cytotoxic against Hela cell at concentrations of up to 20 μM, with only compound LKN10 showing modest cytotoxic activity of 9.5 μM. This research went on to identify two thiosemicarbazone based derivatives which had a significant effect on HeLa and pLDH cells. , Thesis (MSc) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Date Issued: 2022-04-06
Photodynamic anticancer and antimicrobial activities of π-extended BODIPY dyes and cationic mitochondria-targeted porphyrins
- Authors: Chiyumba, Choonzo Nachoobe
- Date: 2022-10-14
- Subjects: Dyes and dyeing Chemistry , Mitochondria , Cancer Chemotherapy , Porphyrins , Molecules Models , Photochemotherapy
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/362785 , vital:65362
- Description: Cancer is among the most devastating diseases and is mainly caused by gene mutation. This could be hereditary, or the mutation could be stimulated due to a lifestyle one lives, such as smoking, which induces lung cancer. The high morbidity rates of cancer are attributed to it being metastatic. The relatively poor physicochemical properties of existing drugs have caused treatment to be ineffective. Photofrin®, Foscan®, and Photogem® are some of the porphyrin-based derivatives approved by the Food and Drug Administration (FDA) for use in photodynamic therapy (PDT). Despite having such drugs, the quest to find better cancer drugs is still ongoing and 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dyes are among the molecules that are being studied as potential photosensitisers (PS) in PDT. However, these molecules suffer from poor solubility and ineffective generation of singlet oxygen, the main ingredient in PDT treatment. Furthermore, photosensitisers used in PDT face a problem with hypoxic conditions associated with cancer cells, which causes the generation of singlet oxygen to be relatively low. The PS also suffer from the untargeted treatment, increasing their toxicity. Therefore, the main aim of this study was to improve the bioavailability of BODIPY dyes. Thus, a series of BODPIY dyes were synthesised with hydrogen bond accepting atoms and heavy atoms that enhance singlet oxygen generation. Additionally, to override hypoxia conditions, porphyrins with mitochondria targeting properties were synthesised since it has been well established that the mitochondria will always have a decent amount of oxygen in cancerous cells. When employed as PS in PDT studies, these molecules have better cytotoxic abilities than BODIPY dyes, and this potency was credited to their mitochondria targeting ability and efficient singlet oxygen generation. Finally, this study reports the synthesis of di- and mono-substituted BODIPY dyes with improved solubility and porphyrins substituted with triphenyl phosphine, a mitochondria targeting moiety. On the other hand, the work further illustrates the synthesis of β-substituted cationic porphyrin with mitochondria targeting properties. , Thesis (MSc) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Chiyumba, Choonzo Nachoobe
- Date: 2022-10-14
- Subjects: Dyes and dyeing Chemistry , Mitochondria , Cancer Chemotherapy , Porphyrins , Molecules Models , Photochemotherapy
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/362785 , vital:65362
- Description: Cancer is among the most devastating diseases and is mainly caused by gene mutation. This could be hereditary, or the mutation could be stimulated due to a lifestyle one lives, such as smoking, which induces lung cancer. The high morbidity rates of cancer are attributed to it being metastatic. The relatively poor physicochemical properties of existing drugs have caused treatment to be ineffective. Photofrin®, Foscan®, and Photogem® are some of the porphyrin-based derivatives approved by the Food and Drug Administration (FDA) for use in photodynamic therapy (PDT). Despite having such drugs, the quest to find better cancer drugs is still ongoing and 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY) dyes are among the molecules that are being studied as potential photosensitisers (PS) in PDT. However, these molecules suffer from poor solubility and ineffective generation of singlet oxygen, the main ingredient in PDT treatment. Furthermore, photosensitisers used in PDT face a problem with hypoxic conditions associated with cancer cells, which causes the generation of singlet oxygen to be relatively low. The PS also suffer from the untargeted treatment, increasing their toxicity. Therefore, the main aim of this study was to improve the bioavailability of BODIPY dyes. Thus, a series of BODPIY dyes were synthesised with hydrogen bond accepting atoms and heavy atoms that enhance singlet oxygen generation. Additionally, to override hypoxia conditions, porphyrins with mitochondria targeting properties were synthesised since it has been well established that the mitochondria will always have a decent amount of oxygen in cancerous cells. When employed as PS in PDT studies, these molecules have better cytotoxic abilities than BODIPY dyes, and this potency was credited to their mitochondria targeting ability and efficient singlet oxygen generation. Finally, this study reports the synthesis of di- and mono-substituted BODIPY dyes with improved solubility and porphyrins substituted with triphenyl phosphine, a mitochondria targeting moiety. On the other hand, the work further illustrates the synthesis of β-substituted cationic porphyrin with mitochondria targeting properties. , Thesis (MSc) -- Faculty of Science, Chemistry, 2022
- Full Text:
- Date Issued: 2022-10-14
Cellphones and whistles: Exploring the communicative ecology and sociality of the Enkanini informal settlement in Makhanda
- Authors: Baloyi, Karabo
- Date: 2021-10-29
- Subjects: Communication models , Cell phones Social aspects South Africa Makhanda , Cell phones Economic aspects South Africa Makhanda , Squatter settlements South Africa Makhanda , South Africa Social conditions 1994- , South Africa Economic conditions 1991- , South Africa Social life and customs , Communication Economic aspects South Africa Makhanda , Whistles South Africa Makhanda , Decolonization South Africa Makhanda , Communicative ecology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191046 , vital:45053
- Description: This thesis explores the communicative ecology in the Enkanini informal settlement in Makhanda, and in particular their use of mobile phones and whistles to build a sense of community. It makes the case for word-of-mouth as an integral part of the communicative ecology despite not being a technological device. It then examines the sociality that arises from the use of these devices, and how coloniality impacts on the participants’ everyday experiences. The research was conducted through telephonic in-depth interviews with participants. To corroborate some of the content drawn from interviews, I used Grocott’s Mail, Makhanda’s only independent newspaper as an archival source, as well as some of the participants’ Facebook profiles. This research argues that as a consequence of coloniality, Enkanini’s residents suffer socio-economic challenges, and thus are unable to use digital technologies as much as they might like to, to communicate with their neighbours. As a consequence, word-of-mouth is their main form of communication with one another. Whistles are the ‘low-tech’ device used for community-wide communication to alert residents of an emergency, or about a meeting or protest. My findings contest generalised claims of society moving towards a network sociality, where individuality and project-based communication is valued over more communal forms of living. They also demonstrate the ways in which coloniality shapes almost every aspect of marginalised people’s lives, making word of mouth the most significant form of communication, notwithstanding the apparent availability of digital technology. It also shows how a marginalised group uses the resources it has to pressure local government officials to provide them with the basis infrastructure they need for survival. , Thesis (MA) -- Faculty of Humanities, Journalism and Media Studies, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Baloyi, Karabo
- Date: 2021-10-29
- Subjects: Communication models , Cell phones Social aspects South Africa Makhanda , Cell phones Economic aspects South Africa Makhanda , Squatter settlements South Africa Makhanda , South Africa Social conditions 1994- , South Africa Economic conditions 1991- , South Africa Social life and customs , Communication Economic aspects South Africa Makhanda , Whistles South Africa Makhanda , Decolonization South Africa Makhanda , Communicative ecology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191046 , vital:45053
- Description: This thesis explores the communicative ecology in the Enkanini informal settlement in Makhanda, and in particular their use of mobile phones and whistles to build a sense of community. It makes the case for word-of-mouth as an integral part of the communicative ecology despite not being a technological device. It then examines the sociality that arises from the use of these devices, and how coloniality impacts on the participants’ everyday experiences. The research was conducted through telephonic in-depth interviews with participants. To corroborate some of the content drawn from interviews, I used Grocott’s Mail, Makhanda’s only independent newspaper as an archival source, as well as some of the participants’ Facebook profiles. This research argues that as a consequence of coloniality, Enkanini’s residents suffer socio-economic challenges, and thus are unable to use digital technologies as much as they might like to, to communicate with their neighbours. As a consequence, word-of-mouth is their main form of communication with one another. Whistles are the ‘low-tech’ device used for community-wide communication to alert residents of an emergency, or about a meeting or protest. My findings contest generalised claims of society moving towards a network sociality, where individuality and project-based communication is valued over more communal forms of living. They also demonstrate the ways in which coloniality shapes almost every aspect of marginalised people’s lives, making word of mouth the most significant form of communication, notwithstanding the apparent availability of digital technology. It also shows how a marginalised group uses the resources it has to pressure local government officials to provide them with the basis infrastructure they need for survival. , Thesis (MA) -- Faculty of Humanities, Journalism and Media Studies, 2021
- Full Text:
- Date Issued: 2021-10-29
Modification of Gelatin-Methacrylate, Hyaluronic-Methacrylate and Poly(ethylene) glycol Diacrylate hydrogel bioinks towards the additive manufacturing of articular cartilage
- Authors: Barwick, Matthew William
- Date: 2021-10
- Subjects: Cartilage Diseases , Cartilage Regeneration , Articular cartilage Diseases , Chondrogenesis , Stem cells , Scanning electron microscopy , Fourier transform infrared spectroscopy , Three-dimensional printing , Gelatin-Methacrylate , Hyaluronic-Methacrylate , Poly(ethylene) glycolDiacrylate , Hydrogel bioinks , Real-Time Quantitative Cell Analysis (RTCA) , Bioprinting
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191181 , vital:45068
- Description: Cartilage degradation is most commonly associated with Rheumatoid arthritis and Osteoarthritis, affecting millions of people worldwide. Joint transplants commonly use titanium alloys, which have a shelf life of between 10-15 years. Although the titanium transplant restores partial mobility, side effects such as inflammation, swelling, faulty implants, and metal poisoning in some cases resulting from the transplant. The use of additive manufacturing of articular cartilage sheds new, innovative prospects for joint replacements. This study sets out to formulate and characterize five different hydrogel types towards the additive manufacturing of articular cartilage. Chondrogenic and Adipogenic differentiation was carried out on two separate adipose-mesenchymal stem cell lines A270620-01A, and A311019-02T and validation and efficiency of the differentiation and chondrogenic gene expression was carried out using Alcian Blue stain, Oil Red O stain and Quantitative Reverse Transcription PCR (RT-qPCR). Hydrogel formulation and characterisation of 10 % Gelatin-methacryloyl (GelMA), 10 % Poly (ethylene) glycol diacrylate (PEGDA), 5 % GelMA/5 % PEGDA, 10 % GelMA/0.5 % Hyaluronic Acid Methacrylate (HAMA) and 10 % PEGDA/0.5 % HAMA was carried out through swelling and degradation ratios, surface area and porosity characterisation using Scanning Electron Microscopy (SEM). Hydrogel component and spectroscopic analysis were carried using Real-Time Quantitative Cell Analysis (RTCA) and Fourier-transform Infrared Spectroscopy (FTIR) analysis for each formulated hydrogel's chemical characterisation. Three-dimensional printing (3D) of 10 % PEGDA/0.5 % HAMA and 5 % GelMA/5 % PEGDA was performed using the Zortrax INKSPIRE Resin Ultra-Violet (UV) LCD Desktop 3D Printer. Hydrogel sterility and cell viability were carried out for each hydrogel type using fluorescence microscopy. Both A270620-01A and A311019-02T cell lines showed adipogenic and chondrogenic differentiation ability, with A311019-02T cell line showing greater chondrogenic differentiation of Alcian blue staining. The A270620-01A cell line resulted in a greater collagen gene expression based on the RT-qPCR results. The hydrogel 10 % GelMA showed the greatest swelling ratio of 1260 % in DPBS and 1192 % in DMEM. A significant difference between hydrogel swelling and swelling with Dulbecco's Phosphate Buffered Saline (DPBS) and Dulbecco’s Modified Eagle Medium (DMEM) was observed. The 10 % PEGDA hydrogel had the greatest degradation ratio of 59 % mass remaining, where the 10 % GelMA/0.5 % HAMA showed the least amount of degradation with a mass remaining at 91 %. The 10 % GelMA showed the greatest porosity will the largest pore size of 14 μm in diameter. Hydrogel component and spectroscopic analysis showed no cytotoxic effects for the visible light photoinitiator used to polymerize the hydrogel and no cytotoxic effects for the concentrations used in chondrogenic differentiation. The FTIR analysis showed partial gelatin and hyaluronic acid modification with methacrylic anhydride; however, the distinction between the hybrid hydrogels and single polymer hydrogels could not be made effectively. UV and ethanol washing showed to completely sterilise the hydrogel disks from any contaminants, making them suitable for tissue culture. The cell viability analysis showed the 10 % GelMA/HAMA having the highest cell viability of 77.3 % using 5000 cells/disk and 89.64 % viability using 50 000 cells/disk over a 7-day incubation period. Overall, the combination of two polymers, GelMA and HAMA, has good potential as a 3D hydrogel scaffold towards additive manufacturing of articular cartilage. , Thesis (MSc) -- Faculty of Science, Biotechnology Innovation Centre, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Barwick, Matthew William
- Date: 2021-10
- Subjects: Cartilage Diseases , Cartilage Regeneration , Articular cartilage Diseases , Chondrogenesis , Stem cells , Scanning electron microscopy , Fourier transform infrared spectroscopy , Three-dimensional printing , Gelatin-Methacrylate , Hyaluronic-Methacrylate , Poly(ethylene) glycolDiacrylate , Hydrogel bioinks , Real-Time Quantitative Cell Analysis (RTCA) , Bioprinting
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191181 , vital:45068
- Description: Cartilage degradation is most commonly associated with Rheumatoid arthritis and Osteoarthritis, affecting millions of people worldwide. Joint transplants commonly use titanium alloys, which have a shelf life of between 10-15 years. Although the titanium transplant restores partial mobility, side effects such as inflammation, swelling, faulty implants, and metal poisoning in some cases resulting from the transplant. The use of additive manufacturing of articular cartilage sheds new, innovative prospects for joint replacements. This study sets out to formulate and characterize five different hydrogel types towards the additive manufacturing of articular cartilage. Chondrogenic and Adipogenic differentiation was carried out on two separate adipose-mesenchymal stem cell lines A270620-01A, and A311019-02T and validation and efficiency of the differentiation and chondrogenic gene expression was carried out using Alcian Blue stain, Oil Red O stain and Quantitative Reverse Transcription PCR (RT-qPCR). Hydrogel formulation and characterisation of 10 % Gelatin-methacryloyl (GelMA), 10 % Poly (ethylene) glycol diacrylate (PEGDA), 5 % GelMA/5 % PEGDA, 10 % GelMA/0.5 % Hyaluronic Acid Methacrylate (HAMA) and 10 % PEGDA/0.5 % HAMA was carried out through swelling and degradation ratios, surface area and porosity characterisation using Scanning Electron Microscopy (SEM). Hydrogel component and spectroscopic analysis were carried using Real-Time Quantitative Cell Analysis (RTCA) and Fourier-transform Infrared Spectroscopy (FTIR) analysis for each formulated hydrogel's chemical characterisation. Three-dimensional printing (3D) of 10 % PEGDA/0.5 % HAMA and 5 % GelMA/5 % PEGDA was performed using the Zortrax INKSPIRE Resin Ultra-Violet (UV) LCD Desktop 3D Printer. Hydrogel sterility and cell viability were carried out for each hydrogel type using fluorescence microscopy. Both A270620-01A and A311019-02T cell lines showed adipogenic and chondrogenic differentiation ability, with A311019-02T cell line showing greater chondrogenic differentiation of Alcian blue staining. The A270620-01A cell line resulted in a greater collagen gene expression based on the RT-qPCR results. The hydrogel 10 % GelMA showed the greatest swelling ratio of 1260 % in DPBS and 1192 % in DMEM. A significant difference between hydrogel swelling and swelling with Dulbecco's Phosphate Buffered Saline (DPBS) and Dulbecco’s Modified Eagle Medium (DMEM) was observed. The 10 % PEGDA hydrogel had the greatest degradation ratio of 59 % mass remaining, where the 10 % GelMA/0.5 % HAMA showed the least amount of degradation with a mass remaining at 91 %. The 10 % GelMA showed the greatest porosity will the largest pore size of 14 μm in diameter. Hydrogel component and spectroscopic analysis showed no cytotoxic effects for the visible light photoinitiator used to polymerize the hydrogel and no cytotoxic effects for the concentrations used in chondrogenic differentiation. The FTIR analysis showed partial gelatin and hyaluronic acid modification with methacrylic anhydride; however, the distinction between the hybrid hydrogels and single polymer hydrogels could not be made effectively. UV and ethanol washing showed to completely sterilise the hydrogel disks from any contaminants, making them suitable for tissue culture. The cell viability analysis showed the 10 % GelMA/HAMA having the highest cell viability of 77.3 % using 5000 cells/disk and 89.64 % viability using 50 000 cells/disk over a 7-day incubation period. Overall, the combination of two polymers, GelMA and HAMA, has good potential as a 3D hydrogel scaffold towards additive manufacturing of articular cartilage. , Thesis (MSc) -- Faculty of Science, Biotechnology Innovation Centre, 2021
- Full Text:
- Date Issued: 2021-10
The tuber-feeding weevil Listronotus frontalis as a candidate biological control agent for the invasive semi-aquatic plant Sagittaria platyphylla within South Africa
- Authors: Rogers, Daniel James
- Date: 2021-10
- Subjects: Listronotus South Africa , Arrowhead (Plants) South Africa , Arrowhead (Plants) Biological control South Africa , Invasive plants Biological control South Africa , Insects as biological pest control agents South Africa , Plant populations South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190731 , vital:45023
- Description: Sagittaria platyphylla (Engelm.) J.G.Sm. (Alismataceae) is an invasive, aquatic macrophyte originating in the southern United States of America. In South Africa, the plant was first detected in Krantzkloof Nature Reserve, KwaZulu-Natal Province in 2008, and due to its known impact in other countries, it was listed as a Category 1a invader species under the National Environmental Management: Biodiversity Act 2004 (NEM:BA). This invasive plant has proved difficult to manage due to its varied growth forms and reproductive strategies, such as prolific seed and below ground tuber production. Due to the limitations of conventional control mechanisms, biological control is currently being considered as a potential control option. The tuber feeding weevil Listronotus frontalis LeConte (Coleoptera: Curculionidae) has been identified as a candidate biological control agent for this invasive species. The aims of this study were twofold; to firstly determine the importance of tubers to S. platyphylla populations growing in South Africa; and secondly, to determine the biology and suitability of L. frontalis, a tuber feeder, as a candidate biological control agent. Surveys of S. platyphylla populations in South Africa showed that tubers were found in all sampled sites, except for Krantzkloof Nature reserve in KwaZulu-Natal Province. The highest number of tubers was 97.75 ± 10.62 (SE) m-2 recorded at Jonkershoek in the Western Cape Province. Monthly sampling from two sites in the Eastern Cape Province, the Makana Botanical Gardens and Maden Dam showed that neither season nor water depth affected tuber production. However, the mean number of tubers as well as mass of tubers sampled, were consistently higher (F(1,179) = 20.9542, P < 0.0001) and heavier (F(1, 857) = 585.7293, P < 0.0001) at the Botanical Gardens than at Maden Dam, respectively. The study showed that tubers are an important life stage of S. platyphylla populations and may vary in size and abundance between and within sites. The tuber feeding weevil was shown to develop from egg to ovipositing adult within just over 40 days. Females were recorded to lay up to 48 eggs within a period of one week. Impact studies showed that adult feeding led to a reduction in all but one of the 11 measured plant growth and developmental measurements, including a reduction in the mean mass of the above-ground plant material (F(2,2743) = 12.05, P = 0.002) as well as a reduction in size and abundance of tubers (F(2,58.47) = 9.756, P = 0.0006) and stolons(F(14.943) = 8.7577, P = 0.003). These results are encouraging and suggest that if the insect is released in South Africa, it may prove to be a valuable biocontrol agent. It is concluded that, until suitable biological control options become available in South Africa, the chemical and mechanical control measures currently implemented should continue, however, controlling tubers should be considered during the planning and implementation of these strategies. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Rogers, Daniel James
- Date: 2021-10
- Subjects: Listronotus South Africa , Arrowhead (Plants) South Africa , Arrowhead (Plants) Biological control South Africa , Invasive plants Biological control South Africa , Insects as biological pest control agents South Africa , Plant populations South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190731 , vital:45023
- Description: Sagittaria platyphylla (Engelm.) J.G.Sm. (Alismataceae) is an invasive, aquatic macrophyte originating in the southern United States of America. In South Africa, the plant was first detected in Krantzkloof Nature Reserve, KwaZulu-Natal Province in 2008, and due to its known impact in other countries, it was listed as a Category 1a invader species under the National Environmental Management: Biodiversity Act 2004 (NEM:BA). This invasive plant has proved difficult to manage due to its varied growth forms and reproductive strategies, such as prolific seed and below ground tuber production. Due to the limitations of conventional control mechanisms, biological control is currently being considered as a potential control option. The tuber feeding weevil Listronotus frontalis LeConte (Coleoptera: Curculionidae) has been identified as a candidate biological control agent for this invasive species. The aims of this study were twofold; to firstly determine the importance of tubers to S. platyphylla populations growing in South Africa; and secondly, to determine the biology and suitability of L. frontalis, a tuber feeder, as a candidate biological control agent. Surveys of S. platyphylla populations in South Africa showed that tubers were found in all sampled sites, except for Krantzkloof Nature reserve in KwaZulu-Natal Province. The highest number of tubers was 97.75 ± 10.62 (SE) m-2 recorded at Jonkershoek in the Western Cape Province. Monthly sampling from two sites in the Eastern Cape Province, the Makana Botanical Gardens and Maden Dam showed that neither season nor water depth affected tuber production. However, the mean number of tubers as well as mass of tubers sampled, were consistently higher (F(1,179) = 20.9542, P < 0.0001) and heavier (F(1, 857) = 585.7293, P < 0.0001) at the Botanical Gardens than at Maden Dam, respectively. The study showed that tubers are an important life stage of S. platyphylla populations and may vary in size and abundance between and within sites. The tuber feeding weevil was shown to develop from egg to ovipositing adult within just over 40 days. Females were recorded to lay up to 48 eggs within a period of one week. Impact studies showed that adult feeding led to a reduction in all but one of the 11 measured plant growth and developmental measurements, including a reduction in the mean mass of the above-ground plant material (F(2,2743) = 12.05, P = 0.002) as well as a reduction in size and abundance of tubers (F(2,58.47) = 9.756, P = 0.0006) and stolons(F(14.943) = 8.7577, P = 0.003). These results are encouraging and suggest that if the insect is released in South Africa, it may prove to be a valuable biocontrol agent. It is concluded that, until suitable biological control options become available in South Africa, the chemical and mechanical control measures currently implemented should continue, however, controlling tubers should be considered during the planning and implementation of these strategies. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2021
- Full Text:
- Date Issued: 2021-10
Characterization of Fluorescently-Labelled Plasmodium Lactate Dehydrogenase-Binding Aptamers for the Detection and Speciation of Malarial Infections
- Authors: Taylor, Bianca Rose
- Date: 2021-10-29
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192572 , vital:45238
- Description: Thesis (MSc) -- Faculty of Science, Biotechnology Innovation Centre, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Taylor, Bianca Rose
- Date: 2021-10-29
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/192572 , vital:45238
- Description: Thesis (MSc) -- Faculty of Science, Biotechnology Innovation Centre, 2021
- Full Text:
- Date Issued: 2021-10-29
Hermēs Dolios: Performances of Hermes as trickster in the Homeric Hymn to Hermes
- Authors: Nel, Aiden Pieter
- Date: 2021-10-29
- Subjects: Hermes (Greek deity) , Hymn to Hermes , Tricksters in literature , Loki (Norse deity) , Hynes, William J , Doty, William G, 1939-J , Wakdjunkaga (Winnebago Trickster) , Ture (Zande Trickster)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190978 , vital:45046
- Description: This thesis explores the Greek god Hermes' representation in the Homeric Hymn to Hermes to establish the extent to which he partakes in Hynes' defined set of characteristics associated with mythological 'trickster' figures. Hermes is an unorthodox figure as although he embodies many aspects of the trickster, he willingly relinquishes some of these aspects within his hymn. I first outline and explore the trickster phenomenon and the complex methodological issue concerning global comparison. Hynes’ criteria are first applied to three other tricksters the Amerindian (Winnebago) trickster Wakdjunkaga, the central African (Azande) trickster Ture and the northern European (Norse) trickster Loki, which establishes a baseline that will help determine how Hermes conforms to this typology. All three figures’ cultural contexts are first addressed, as the cultural context is key in understanding a figure’s potential inclusion in the trickster category. I then explore Hermes’ performances within his hymn and other genres to formulate how his patron powers and actions relate to his designation as a trickster. I argue, in conclusion, that Hynes’ typology is a useful tool in determining any figure’s degree of ‘tricksterness’ and show that Hermes and the other three figures do embody Hynes’ characteristics. Each, however, embodies them differently and in a specific manner. I argue that the manner in which they relate to the criteria is dictated by their respective cultural contexts, and what their narrators intended to illustrate through the stories wherein tricksters reside. I further argue that narrative intent, genre and cultural context appear to be the main factors that mould each respective figure. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Nel, Aiden Pieter
- Date: 2021-10-29
- Subjects: Hermes (Greek deity) , Hymn to Hermes , Tricksters in literature , Loki (Norse deity) , Hynes, William J , Doty, William G, 1939-J , Wakdjunkaga (Winnebago Trickster) , Ture (Zande Trickster)
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190978 , vital:45046
- Description: This thesis explores the Greek god Hermes' representation in the Homeric Hymn to Hermes to establish the extent to which he partakes in Hynes' defined set of characteristics associated with mythological 'trickster' figures. Hermes is an unorthodox figure as although he embodies many aspects of the trickster, he willingly relinquishes some of these aspects within his hymn. I first outline and explore the trickster phenomenon and the complex methodological issue concerning global comparison. Hynes’ criteria are first applied to three other tricksters the Amerindian (Winnebago) trickster Wakdjunkaga, the central African (Azande) trickster Ture and the northern European (Norse) trickster Loki, which establishes a baseline that will help determine how Hermes conforms to this typology. All three figures’ cultural contexts are first addressed, as the cultural context is key in understanding a figure’s potential inclusion in the trickster category. I then explore Hermes’ performances within his hymn and other genres to formulate how his patron powers and actions relate to his designation as a trickster. I argue, in conclusion, that Hynes’ typology is a useful tool in determining any figure’s degree of ‘tricksterness’ and show that Hermes and the other three figures do embody Hynes’ characteristics. Each, however, embodies them differently and in a specific manner. I argue that the manner in which they relate to the criteria is dictated by their respective cultural contexts, and what their narrators intended to illustrate through the stories wherein tricksters reside. I further argue that narrative intent, genre and cultural context appear to be the main factors that mould each respective figure. , Thesis (MA) -- Faculty of Humanities, School of Languages and Literatures, 2021
- Full Text:
- Date Issued: 2021-10-29
Archontic Aporias: the mediums of memory
- Authors: Arbuckle, Julia Ruth
- Date: 2023-03-30
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408727 , vital:70520
- Description: Contextualising my research within the Eastern Cape as a descendant of 1820 settlers, I question the modalities of historical recollection by introducing memory as a viable mode of archival production alongside that of the archive. Through interrogating Eastern Cape archival institutes and employing an autoethnographic approach to my familial archives, I show that archival curation affects the gaps, schisms, and interpretations of archives as much as the ‘unreliability’ of memory. I rely on definitions from Jacques Derrida and literature from Achille Mbembe and Verne Harris, as well as reflexive methodologies, to engage the ways of remembering the past and methods of storytelling. With this undertaking, I expose the aporias within archival processes. This written component is part of broader research that encompasses theoretical study and a practice-based Fine Arts research project culminating in an exhibition that shares themes of memory, archive, trauma, and curatorial and personal heritage management. This research engages in case studies of artworks by Angela Deane and Maureen de Jager to contextualise and position the creative process. , Thesis (MFA) -- Faculty of Humanities, Fine Art, 2023
- Full Text:
- Date Issued: 2023-03-30
- Authors: Arbuckle, Julia Ruth
- Date: 2023-03-30
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408727 , vital:70520
- Description: Contextualising my research within the Eastern Cape as a descendant of 1820 settlers, I question the modalities of historical recollection by introducing memory as a viable mode of archival production alongside that of the archive. Through interrogating Eastern Cape archival institutes and employing an autoethnographic approach to my familial archives, I show that archival curation affects the gaps, schisms, and interpretations of archives as much as the ‘unreliability’ of memory. I rely on definitions from Jacques Derrida and literature from Achille Mbembe and Verne Harris, as well as reflexive methodologies, to engage the ways of remembering the past and methods of storytelling. With this undertaking, I expose the aporias within archival processes. This written component is part of broader research that encompasses theoretical study and a practice-based Fine Arts research project culminating in an exhibition that shares themes of memory, archive, trauma, and curatorial and personal heritage management. This research engages in case studies of artworks by Angela Deane and Maureen de Jager to contextualise and position the creative process. , Thesis (MFA) -- Faculty of Humanities, Fine Art, 2023
- Full Text:
- Date Issued: 2023-03-30
Stakeholder relationship management and the perception of trust: a case study of a salient stakeholder
- Authors: Chambers, Craig Brian
- Date: 2022-06
- Subjects: Stakeholder management South Africa Sundays River (Eastern Cape) , Stakeholder theory , Trust , Industrial priorities , Social capital (Sociology)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419060 , vital:71612
- Description: Trust is an essential aspect in developing meaningful relationships between firms and their stakeholders. Mayer, Davis and Schoorman (1995, p.709) define trust as “the willingness of a party to be vulnerable to the actions of another party based on the expectation that the other party will perform a particular action important to the trustor irrespective of the ability to monitor or control that other party”. This study took the form of an explanatory case study that focussed on an interaction between a firm and a salient stakeholder and attempted to explain how this interaction influenced the perceived trustworthiness of the firm in stakeholders that were observing the interaction. The study attempted to add to the work of Crane (2020), whose research had focussed on stakeholder connectedness, and specifically how this could be utilized by firms interacting with stakeholders to engender trust in a wider group of stakeholders. The research aimed to evaluate how the Sterile Insect Release programme, operating by the firm in the Sunday’s River Valley, was given a second chance through engagement with a salient stakeholder and how the interaction was observed by a wider group of stakeholders leading to perceived stakeholder trustworthiness and social capital. The study had five objectives, namely to; (1) analyse how a firm’s ability, benevolence, and integrity enables (or does not engender) the development of the firm’s trustworthiness amongst its stakeholders; (2) analyse how the firm’s engagement with a salient stakeholder enables (or does not engender) increased levels of trustworthiness in the firm by the stakeholders that are observing its interaction with a salient stakeholder; (3) analyse the benefits of social capital gained through increased levels of stakeholder trust; (4) identify good practice guidelines for firm engagement with salient stakeholders to ensure the correct cues are portrayed to observing stakeholders for the development of the trustworthiness of the firm; and (5) make recommendations related to management practices that will support the development of trust. The research adopted a qualitative approach and data were collected through semi-structured interviews with three groups of stakeholders that were present at the meeting. A review of the literature was undertaken to identify various propositions for the research and from which a theory-driven coding memo was developed. The derived propositions were as follows: (1) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the trustworthiness of the firm, and (2) perceptions of a firm’s trustworthiness will result in increased social capital between the firm and its stakeholders. The first proposition was divided into three sub-propositions for the study which stated; (a) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the ability of the firm; (b) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the benevolence of the firm; and (c) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the integrity of the firm. From the literature analysis, various themes were identified which include, observed interactions, ability, benevolence, integrity, trustworthiness, and increased social capital. The research findings confirmed the propositions as being relevant to the case study. The findings confirmed that ability, benevolence, and integrity are key attributes in portraying trustworthiness when interacting with a salient stakeholder. All three attributes were noted by the interviewees as being important to observing stakeholders in the development of trust in a firm, although ability and integrity were found to be the dominant attributes in this case study. The findings did present some evidence that an increased level of perceived trustworthiness in the firm did positively influence the levels of social capital, however, this was not a common theme among all the interviewees. In the light of these findings, it is recommended that firms utilize stakeholder models to identify salient stakeholders that are influential within the markets in which they operate. The firm should actively pursue a strong relationship with these stakeholders, and further attempt to generate opportunities to interact with these stakeholders in a public forum where stakeholder connectedness could be utilized to develop perceived trust in the wider group of stakeholders. The firm should focus on open, honest, and transparent communication which are key aspects for portraying the attributes of ability, benevolence, and integrity. The study addresses a gap in the trust literature at a stakeholder level and therefore has contributed to the trust literature by addressing how the connectedness between stakeholders can lead to trust in a wider group of stakeholders by increasing efficiency during these interactions and utilizing situational circumstances to build social capital. , Thesis (MBA) -- Faculty of Commerce, Rhodes Business School, 2023
- Full Text:
- Date Issued: 2022-06
- Authors: Chambers, Craig Brian
- Date: 2022-06
- Subjects: Stakeholder management South Africa Sundays River (Eastern Cape) , Stakeholder theory , Trust , Industrial priorities , Social capital (Sociology)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419060 , vital:71612
- Description: Trust is an essential aspect in developing meaningful relationships between firms and their stakeholders. Mayer, Davis and Schoorman (1995, p.709) define trust as “the willingness of a party to be vulnerable to the actions of another party based on the expectation that the other party will perform a particular action important to the trustor irrespective of the ability to monitor or control that other party”. This study took the form of an explanatory case study that focussed on an interaction between a firm and a salient stakeholder and attempted to explain how this interaction influenced the perceived trustworthiness of the firm in stakeholders that were observing the interaction. The study attempted to add to the work of Crane (2020), whose research had focussed on stakeholder connectedness, and specifically how this could be utilized by firms interacting with stakeholders to engender trust in a wider group of stakeholders. The research aimed to evaluate how the Sterile Insect Release programme, operating by the firm in the Sunday’s River Valley, was given a second chance through engagement with a salient stakeholder and how the interaction was observed by a wider group of stakeholders leading to perceived stakeholder trustworthiness and social capital. The study had five objectives, namely to; (1) analyse how a firm’s ability, benevolence, and integrity enables (or does not engender) the development of the firm’s trustworthiness amongst its stakeholders; (2) analyse how the firm’s engagement with a salient stakeholder enables (or does not engender) increased levels of trustworthiness in the firm by the stakeholders that are observing its interaction with a salient stakeholder; (3) analyse the benefits of social capital gained through increased levels of stakeholder trust; (4) identify good practice guidelines for firm engagement with salient stakeholders to ensure the correct cues are portrayed to observing stakeholders for the development of the trustworthiness of the firm; and (5) make recommendations related to management practices that will support the development of trust. The research adopted a qualitative approach and data were collected through semi-structured interviews with three groups of stakeholders that were present at the meeting. A review of the literature was undertaken to identify various propositions for the research and from which a theory-driven coding memo was developed. The derived propositions were as follows: (1) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the trustworthiness of the firm, and (2) perceptions of a firm’s trustworthiness will result in increased social capital between the firm and its stakeholders. The first proposition was divided into three sub-propositions for the study which stated; (a) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the ability of the firm; (b) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the benevolence of the firm; and (c) observing a firm’s engagement with a single salient stakeholder will provide cues to observing stakeholders about the integrity of the firm. From the literature analysis, various themes were identified which include, observed interactions, ability, benevolence, integrity, trustworthiness, and increased social capital. The research findings confirmed the propositions as being relevant to the case study. The findings confirmed that ability, benevolence, and integrity are key attributes in portraying trustworthiness when interacting with a salient stakeholder. All three attributes were noted by the interviewees as being important to observing stakeholders in the development of trust in a firm, although ability and integrity were found to be the dominant attributes in this case study. The findings did present some evidence that an increased level of perceived trustworthiness in the firm did positively influence the levels of social capital, however, this was not a common theme among all the interviewees. In the light of these findings, it is recommended that firms utilize stakeholder models to identify salient stakeholders that are influential within the markets in which they operate. The firm should actively pursue a strong relationship with these stakeholders, and further attempt to generate opportunities to interact with these stakeholders in a public forum where stakeholder connectedness could be utilized to develop perceived trust in the wider group of stakeholders. The firm should focus on open, honest, and transparent communication which are key aspects for portraying the attributes of ability, benevolence, and integrity. The study addresses a gap in the trust literature at a stakeholder level and therefore has contributed to the trust literature by addressing how the connectedness between stakeholders can lead to trust in a wider group of stakeholders by increasing efficiency during these interactions and utilizing situational circumstances to build social capital. , Thesis (MBA) -- Faculty of Commerce, Rhodes Business School, 2023
- Full Text:
- Date Issued: 2022-06
Reforging Ockham’s Razor: an enquiry into the ontology of parsimony arguments
- Authors: Dichmont, Thomas
- Date: 2022-10-14
- Subjects: Logic , Metaphysics , Ontology , Knowledge, Theory of , Epistemology , Philosophy and science , Occam's razor
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406736 , vital:70303
- Description: Nearly every philosopher in English-speaking world has heard of Ockham’s Razor, which is given in one of two ways, don’t multiply entities beyond necessity and all things being equal choose the simpler explanation. Yet it is unclear from the scholarship whether the use of Ockham’s Razor is justified in science and philosophy. However, if it can be shown to ‘get’ us truth, it would gain an unequivocal justification, as disputes that are continued after the parties to the substantive truth of one or the other are defined as frivolous. Alternative, one may contend that explanation could have other criteria of success. The implication of a direct connection between the razor and truth comes with ontological commitments, namely a commitment to realism (about universals) and philosophical theism. This is contrary to the razor’s use as a tool of nominalism and naturalism. I argue in this thesis there that the only possible non-circular justification for Ockham’s Razor is truth and that therefore certain philosophical positions are excluded from using the razor to animate their positions. There is an additional, second criteria for the success of our inquiry, namely the justification must in some way be consistent with the razor, which means the chosen explanation for the razor, must be simpler than any of its rivals and not have superfluous entities, otherwise our justification would be contrary to the advice of the razor. We are presented with a Scylla and Charybdis type problem, we avoid a circularity on the one hand and on the other we must not contradict the razor itself, these are contrary intellectual impulses. So firstly I will look at disciplines outside philosophy for some initial inspiration. If we could answer this question in a ‘non’ philosophical way, the problem would have solved itself in a way that require little change of practice. If lawyers or scientist can account for the razor properly, there is not really a problem of justification, at least not a philosophical one. Second, I consider the realist and theist positions, namely an argument of Aristotle’s in the Posterior Analytics and part of Aquinas’ On the Divine Simplicity. Further, I consider the work of Ockham as a nominalist. Lastly, I consider modern and contemporary philosophy, in the form of Hume, Quine and Sober (a modern writer on the razor). The aim here is to ‘stress test’ the philosophical resources of the various systems and analyse the results to see if they can produce a non-circular result. , Thesis (MA) -- Faculty of Humanities, Philosophy, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Dichmont, Thomas
- Date: 2022-10-14
- Subjects: Logic , Metaphysics , Ontology , Knowledge, Theory of , Epistemology , Philosophy and science , Occam's razor
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/406736 , vital:70303
- Description: Nearly every philosopher in English-speaking world has heard of Ockham’s Razor, which is given in one of two ways, don’t multiply entities beyond necessity and all things being equal choose the simpler explanation. Yet it is unclear from the scholarship whether the use of Ockham’s Razor is justified in science and philosophy. However, if it can be shown to ‘get’ us truth, it would gain an unequivocal justification, as disputes that are continued after the parties to the substantive truth of one or the other are defined as frivolous. Alternative, one may contend that explanation could have other criteria of success. The implication of a direct connection between the razor and truth comes with ontological commitments, namely a commitment to realism (about universals) and philosophical theism. This is contrary to the razor’s use as a tool of nominalism and naturalism. I argue in this thesis there that the only possible non-circular justification for Ockham’s Razor is truth and that therefore certain philosophical positions are excluded from using the razor to animate their positions. There is an additional, second criteria for the success of our inquiry, namely the justification must in some way be consistent with the razor, which means the chosen explanation for the razor, must be simpler than any of its rivals and not have superfluous entities, otherwise our justification would be contrary to the advice of the razor. We are presented with a Scylla and Charybdis type problem, we avoid a circularity on the one hand and on the other we must not contradict the razor itself, these are contrary intellectual impulses. So firstly I will look at disciplines outside philosophy for some initial inspiration. If we could answer this question in a ‘non’ philosophical way, the problem would have solved itself in a way that require little change of practice. If lawyers or scientist can account for the razor properly, there is not really a problem of justification, at least not a philosophical one. Second, I consider the realist and theist positions, namely an argument of Aristotle’s in the Posterior Analytics and part of Aquinas’ On the Divine Simplicity. Further, I consider the work of Ockham as a nominalist. Lastly, I consider modern and contemporary philosophy, in the form of Hume, Quine and Sober (a modern writer on the razor). The aim here is to ‘stress test’ the philosophical resources of the various systems and analyse the results to see if they can produce a non-circular result. , Thesis (MA) -- Faculty of Humanities, Philosophy, 2022
- Full Text:
- Date Issued: 2022-10-14
The role of a national system of innovation in facilitating development in South Africa from a comparative BRICS perspective
- Authors: Sibhukwana, Andiswa
- Date: 2022-04-06
- Subjects: BRIC countries , Technological innovations Economic aspects South Africa , Economic development South Africa , Economics Mathematical models , Neoclassical school of economics , South Africa Economic conditions , South Africa Economic policy , National systems of innovation
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284616 , vital:56079
- Description: The aim of the dissertation was to investigate whether the adoption of a national system of innovation has helped facilitate development in South Africa from a comparative BRICS perspective. South Africa has an expanding focus on science and technology, as per the Science and Technology White Paper (1996). There appeared to be innovation that had left out much of the citizenry. There continued to be poverty, inequality, and joblessness. The study aimed to understand how the NSI approach could be used to foster inclusive and transformative development. The study used a mixed-methods approach. The qualitative aspect of the research focused on an innovation and public policy study which assessed the various policies and initiatives implemented in each of the BRICS countries to drive innovation and foster development. The qualitative aspect of the study found that the innovation paradigm required governments to adopt a more holistic approach to public policy design and analysis. The quantitative aspect of the research focused on a trend, correlation, and regression analysis. The trend analysis revealed that China and Brazil increased their allocation of resources towards R&D compared to the other countries. Brazil is regarded as a social investment state, while China is a developmental state: this means the state plays an extraordinarily strong coordinative and financing role in the NSI. On the other hand, the correlation matrix for South Africa revealed a statistically significant positive linear association between various NSI indicators and human development. This suggested that the innovation benefits are trickling down to the general citizenry. In essence the study articulated key elements of the understanding of current and potential impacts of technological change in productivity and growth, employment and inequality that can be used for policy making. , Thesis (MEcon) -- Faculty of Commerce, Economics and Economic History, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Sibhukwana, Andiswa
- Date: 2022-04-06
- Subjects: BRIC countries , Technological innovations Economic aspects South Africa , Economic development South Africa , Economics Mathematical models , Neoclassical school of economics , South Africa Economic conditions , South Africa Economic policy , National systems of innovation
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/284616 , vital:56079
- Description: The aim of the dissertation was to investigate whether the adoption of a national system of innovation has helped facilitate development in South Africa from a comparative BRICS perspective. South Africa has an expanding focus on science and technology, as per the Science and Technology White Paper (1996). There appeared to be innovation that had left out much of the citizenry. There continued to be poverty, inequality, and joblessness. The study aimed to understand how the NSI approach could be used to foster inclusive and transformative development. The study used a mixed-methods approach. The qualitative aspect of the research focused on an innovation and public policy study which assessed the various policies and initiatives implemented in each of the BRICS countries to drive innovation and foster development. The qualitative aspect of the study found that the innovation paradigm required governments to adopt a more holistic approach to public policy design and analysis. The quantitative aspect of the research focused on a trend, correlation, and regression analysis. The trend analysis revealed that China and Brazil increased their allocation of resources towards R&D compared to the other countries. Brazil is regarded as a social investment state, while China is a developmental state: this means the state plays an extraordinarily strong coordinative and financing role in the NSI. On the other hand, the correlation matrix for South Africa revealed a statistically significant positive linear association between various NSI indicators and human development. This suggested that the innovation benefits are trickling down to the general citizenry. In essence the study articulated key elements of the understanding of current and potential impacts of technological change in productivity and growth, employment and inequality that can be used for policy making. , Thesis (MEcon) -- Faculty of Commerce, Economics and Economic History, 2022
- Full Text:
- Date Issued: 2022-04-06
Gamification technology in teaching: Exploring how mathematics teachers make use of Kahoot! Gamification to facilitate learning of probability in classrooms
- Authors: Mbete, Ayanda
- Date: 2022-10-14
- Subjects: Gamification , Kahoot! , Mathematics Study and teaching (Elementary) South Africa Eastern Cape , Probabilities , Educational technology , Rural schools South Africa Eastern Cape , Technological Pedagogical Content Knowledge , Cultural-historical activity theory
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/405311 , vital:70160
- Description: This study seeks to examine the use of Kahoot! as a gamification technology in practice with Grade six teachers to explore its use in supporting the learning of Probability in Mathematics in rural primary schools. Purposive sampling was adopted wherein nine Grade six mathematics teachers from four rural primary schools in Amathole East district were selected as participants of the study. In addition, to inform this qualitative case study, an interpretive paradigm was adopted. Data was collected using semi-questionnaires, semi-structured interviews, non-participant observations, workshop discussions and reflective journals. The TPACK by Mishra & Koehler (2009) and Vygotsky’s (1978) socio-cultural theory were employed as the lenses through which all the proceedings of the study were based. The key findings indicate that integrating Kahoot! gamification technology, in the ‘Probability’ lesson, has positive consequences such as bringing fun into the classroom, enhancing learner participation, prompt feedback and offering a learner-driven approach to learning as opposed to the conventional teaching strategies. The findings also revealed that enabling and constraining factors are associated with using Kahoot! in teaching: the ICT infrastructure, teachers’ competency levels and the environment in which teaching and learning occurs. This study concluded that the use of Kahoot enhances the learning of probability in rural under-resourced primary schools. This study recommended the integration of Kahoot gamification into the mathematics curriculum. , Thesis (MEd) -- Faculty of Education, Education, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Mbete, Ayanda
- Date: 2022-10-14
- Subjects: Gamification , Kahoot! , Mathematics Study and teaching (Elementary) South Africa Eastern Cape , Probabilities , Educational technology , Rural schools South Africa Eastern Cape , Technological Pedagogical Content Knowledge , Cultural-historical activity theory
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/405311 , vital:70160
- Description: This study seeks to examine the use of Kahoot! as a gamification technology in practice with Grade six teachers to explore its use in supporting the learning of Probability in Mathematics in rural primary schools. Purposive sampling was adopted wherein nine Grade six mathematics teachers from four rural primary schools in Amathole East district were selected as participants of the study. In addition, to inform this qualitative case study, an interpretive paradigm was adopted. Data was collected using semi-questionnaires, semi-structured interviews, non-participant observations, workshop discussions and reflective journals. The TPACK by Mishra & Koehler (2009) and Vygotsky’s (1978) socio-cultural theory were employed as the lenses through which all the proceedings of the study were based. The key findings indicate that integrating Kahoot! gamification technology, in the ‘Probability’ lesson, has positive consequences such as bringing fun into the classroom, enhancing learner participation, prompt feedback and offering a learner-driven approach to learning as opposed to the conventional teaching strategies. The findings also revealed that enabling and constraining factors are associated with using Kahoot! in teaching: the ICT infrastructure, teachers’ competency levels and the environment in which teaching and learning occurs. This study concluded that the use of Kahoot enhances the learning of probability in rural under-resourced primary schools. This study recommended the integration of Kahoot gamification into the mathematics curriculum. , Thesis (MEd) -- Faculty of Education, Education, 2022
- Full Text:
- Date Issued: 2022-10-14
Employee views on organisational effectiveness of Chinese organisations operating in Kenya
- Mlotshwa, Minenhle Petronella
- Authors: Mlotshwa, Minenhle Petronella
- Date: 2021-10-29
- Subjects: Organizational effectiveness Kenya , Corporate culture Kenya Cross-cultural studies , China Foreign economic relations Kenya , International business enterprises Kenya , International business enterprises Personnel management , Bilingual communication in organizations Kenya , Religion in the workplace Kenya Cross-cultural studies , Work ethic Kenya Cross-cultural studies
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191898 , vital:45177
- Description: Over the years there has been a growing interest in the relations between Africa and Asia. This is attributed to what is perceived as increasing Chinese influence and presence in Africa. During the past decades, China has experienced rapid economic growth and expansion which has contributed to its need for additional resources and expanding its geographic footprint into Africa and especially Kenya. The growing presence of Chinese organisations in Africa has also faced challenges. Chinese organisations operating in Kenya have been cited as facing cultural challenges, human resource management issues and external pressures which affect Chinese organisations thus impacting organisational effectiveness and performance. While there has been an abundance of research conducted at a macro level, mainly anecdotal knowledge on Chinese organisational values and management, little information exists at the organisation and community level. This study aimed to contribute an in-depth understanding of Chinese and Kenyan employee relationships in organisations at a micro level. Furthermore, this study assesses employees’ views on organisational effectiveness in a cross-cultural research setting of selected Chinese organisations operating in Kenya using the Burke-Litwin model (1992) of organisational effectiveness. This study is qualitative in nature within the interpretivistic research paradigm and used a case study approach to generate detailed comprehensive understanding of the phenomenon under investigation. Two Chinese organisations specialising in importing and exporting of diverse products, which had expanded its operations to Kenya in order to reach Africa’s growing consumer markets were selected for this study. The selected organisations were chosen under the premises that they had been operating in Kenya for more than 20 years, they are reputable organisations in their industries and were international role players. Non-probability convenience sampling was used to select the two organisations who were willing to participate. Purposive sampling was used to identify employees from different job levels and types of work in the selected organisations who were willing to participate in this study. Data was collected by means of face-to-face open-ended semi-structured interviews, with five Chinese and 12 Kenyan employees. The findings of this study were guided by the dimensions of the Burke-Litwin model, comprising the external environment, transformational dimensions (including mission and strategy, leadership and organisational culture) and transactional dimensions (including management practices, organisational structure, systems [policies and procedures], motivation, work climate, task requirements and individual skills and abilities). Based on the findings, organisational culture was the dominant theme that had a large influence on the organisational performance. Within the context of organisational culture, the main challenges faced by employees were religious, work ethic and communication barriers. Leadership and the organisational structure set by senior managers was also impacted by culture. It is evident that the Chinese organisations are dominated by Chinese employees at senior managerial levels – except for one Indian Kenyan manager – and non-managerial levels are dominated by Kenyan employees. Between these two managerial levels there is lack of trust as well as trade union interference favouring Kenyan employees. Leadership of the selected organisations aimed at recruiting candidates who have the necessary skills to contribute toward organisational effectiveness and performance. However, recruited Kenyan employees indicated that they require strategy visibility, effective communication, and structured processes in order to be effective. Despite challenges faced, Chinese and Kenyan employees both strongly agree with and support the efforts of management for providing training and development and creating an environment that accommodates personal growth. The external environment has exerted pressure on the said Chinese organisations. The Kenyan trade unions favour Kenyan employees and place huge pressure on Chinese management. In addition the trade unions bribe locals while making it difficult for Chinese organisations operating in Kenya to conduct business. Through the empirical development of organisational-level research on the case of Chinese organisations operating in Kenya, insightful management knowledge was gathered and shared to assist Chinese and Kenyan employees in their individual and organisational performance. , Thesis (MCom) -- Faculty of Commerce, Management, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Mlotshwa, Minenhle Petronella
- Date: 2021-10-29
- Subjects: Organizational effectiveness Kenya , Corporate culture Kenya Cross-cultural studies , China Foreign economic relations Kenya , International business enterprises Kenya , International business enterprises Personnel management , Bilingual communication in organizations Kenya , Religion in the workplace Kenya Cross-cultural studies , Work ethic Kenya Cross-cultural studies
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/191898 , vital:45177
- Description: Over the years there has been a growing interest in the relations between Africa and Asia. This is attributed to what is perceived as increasing Chinese influence and presence in Africa. During the past decades, China has experienced rapid economic growth and expansion which has contributed to its need for additional resources and expanding its geographic footprint into Africa and especially Kenya. The growing presence of Chinese organisations in Africa has also faced challenges. Chinese organisations operating in Kenya have been cited as facing cultural challenges, human resource management issues and external pressures which affect Chinese organisations thus impacting organisational effectiveness and performance. While there has been an abundance of research conducted at a macro level, mainly anecdotal knowledge on Chinese organisational values and management, little information exists at the organisation and community level. This study aimed to contribute an in-depth understanding of Chinese and Kenyan employee relationships in organisations at a micro level. Furthermore, this study assesses employees’ views on organisational effectiveness in a cross-cultural research setting of selected Chinese organisations operating in Kenya using the Burke-Litwin model (1992) of organisational effectiveness. This study is qualitative in nature within the interpretivistic research paradigm and used a case study approach to generate detailed comprehensive understanding of the phenomenon under investigation. Two Chinese organisations specialising in importing and exporting of diverse products, which had expanded its operations to Kenya in order to reach Africa’s growing consumer markets were selected for this study. The selected organisations were chosen under the premises that they had been operating in Kenya for more than 20 years, they are reputable organisations in their industries and were international role players. Non-probability convenience sampling was used to select the two organisations who were willing to participate. Purposive sampling was used to identify employees from different job levels and types of work in the selected organisations who were willing to participate in this study. Data was collected by means of face-to-face open-ended semi-structured interviews, with five Chinese and 12 Kenyan employees. The findings of this study were guided by the dimensions of the Burke-Litwin model, comprising the external environment, transformational dimensions (including mission and strategy, leadership and organisational culture) and transactional dimensions (including management practices, organisational structure, systems [policies and procedures], motivation, work climate, task requirements and individual skills and abilities). Based on the findings, organisational culture was the dominant theme that had a large influence on the organisational performance. Within the context of organisational culture, the main challenges faced by employees were religious, work ethic and communication barriers. Leadership and the organisational structure set by senior managers was also impacted by culture. It is evident that the Chinese organisations are dominated by Chinese employees at senior managerial levels – except for one Indian Kenyan manager – and non-managerial levels are dominated by Kenyan employees. Between these two managerial levels there is lack of trust as well as trade union interference favouring Kenyan employees. Leadership of the selected organisations aimed at recruiting candidates who have the necessary skills to contribute toward organisational effectiveness and performance. However, recruited Kenyan employees indicated that they require strategy visibility, effective communication, and structured processes in order to be effective. Despite challenges faced, Chinese and Kenyan employees both strongly agree with and support the efforts of management for providing training and development and creating an environment that accommodates personal growth. The external environment has exerted pressure on the said Chinese organisations. The Kenyan trade unions favour Kenyan employees and place huge pressure on Chinese management. In addition the trade unions bribe locals while making it difficult for Chinese organisations operating in Kenya to conduct business. Through the empirical development of organisational-level research on the case of Chinese organisations operating in Kenya, insightful management knowledge was gathered and shared to assist Chinese and Kenyan employees in their individual and organisational performance. , Thesis (MCom) -- Faculty of Commerce, Management, 2021
- Full Text:
- Date Issued: 2021-10-29
“Un-silencing queer Nigeria”: Representations of queerness in contemporary Nigerian fiction
- Authors: Akram, Tahzeeb
- Date: 2021-10-29
- Subjects: Heterosexism in literature , Patriarchy in literature , Homophobia in literature , Sexual minorities in literature , Nigerian literature 21st century History and criticism , Queer theory Nigeria , Gender identity Law and legislation Nigeria , Gender identity Religious aspects , Sexual minorities Nigeria Social conditions , Nigeria. Same Sex Marriage (Prohibition) Act, 2013
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190668 , vital:45016
- Description: This thesis analyses contemporary queer Nigerian fiction, particularly queer representations regarding law, religion and culture in Nigeria’s heteropatriarchal and queerphobic society. I explore a number of authors’ use of different literary forms and platforms to promote and represent non-conforming genders and sexualities in queerphobic Nigeria. These narratives show queer people navigating the heteronormative society vis-à-vis marriage, family, intimacy, work, violence and rights activism. I draw on Western and African gender and queer theories for the concepts, definitions and critical terminologies used in this thesis. African queer theorists and activists are highlighted for their reclaiming queer history from among the early records in Africa as well as contemporary queer Nigerian literature and activism. Religion and queerness are crucial themes in Chinelo Okparanta’s same sex women’s novel, Under the Udala Trees. Using queer African Christian theology against Nigeria’s conservative socio-religious setting, I demonstrate that queerness is not a threat to Nigerian’s Christian faith, and that mutual coexistence of queer sexuality and Christianity advances queer rights in that society. Nnanna Ikpo’s Fimí Sílẹ̀ Forever: Heaven gave it to me’s problematises heteronormative masculinities and the manufacturing of heteropatriarchy and queer masculinities in Nigeria. I examine the protagonists who are both victims of and perpetrators in their queerphobic society. The socio-legal focus I employ examines the impact of the 2014 Same Sex Marriage Prohibition Act on Nigeria’s already marginalised and oppressed queer community. There are vast opportunities for queer Nigerian artists to create, publish and promote queer identities in the safe and enabling space of online platforms via physical distancing between the queer community and the queerphobic society. From the digitally published 14: An Anthology of Queer Art’s two volumes, five short stories are analysed regarding different forms of intimacies in queer men’s relationships. These queer contemporary fiction writers offer complex representations of queerness within Nigeria’s heteropatriarchal and queerphobic society that polices non-normative bodies through religion, culture and the law. Such literary texts, digital literary platforms and activism vitally provide queer Nigerians a progressive space to assert queer presence, voices lives and rights to educating and re-socialising their society towards humaneness. , Thesis (MA) -- Faculty of Humanities, Literary Studies in English, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Akram, Tahzeeb
- Date: 2021-10-29
- Subjects: Heterosexism in literature , Patriarchy in literature , Homophobia in literature , Sexual minorities in literature , Nigerian literature 21st century History and criticism , Queer theory Nigeria , Gender identity Law and legislation Nigeria , Gender identity Religious aspects , Sexual minorities Nigeria Social conditions , Nigeria. Same Sex Marriage (Prohibition) Act, 2013
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190668 , vital:45016
- Description: This thesis analyses contemporary queer Nigerian fiction, particularly queer representations regarding law, religion and culture in Nigeria’s heteropatriarchal and queerphobic society. I explore a number of authors’ use of different literary forms and platforms to promote and represent non-conforming genders and sexualities in queerphobic Nigeria. These narratives show queer people navigating the heteronormative society vis-à-vis marriage, family, intimacy, work, violence and rights activism. I draw on Western and African gender and queer theories for the concepts, definitions and critical terminologies used in this thesis. African queer theorists and activists are highlighted for their reclaiming queer history from among the early records in Africa as well as contemporary queer Nigerian literature and activism. Religion and queerness are crucial themes in Chinelo Okparanta’s same sex women’s novel, Under the Udala Trees. Using queer African Christian theology against Nigeria’s conservative socio-religious setting, I demonstrate that queerness is not a threat to Nigerian’s Christian faith, and that mutual coexistence of queer sexuality and Christianity advances queer rights in that society. Nnanna Ikpo’s Fimí Sílẹ̀ Forever: Heaven gave it to me’s problematises heteronormative masculinities and the manufacturing of heteropatriarchy and queer masculinities in Nigeria. I examine the protagonists who are both victims of and perpetrators in their queerphobic society. The socio-legal focus I employ examines the impact of the 2014 Same Sex Marriage Prohibition Act on Nigeria’s already marginalised and oppressed queer community. There are vast opportunities for queer Nigerian artists to create, publish and promote queer identities in the safe and enabling space of online platforms via physical distancing between the queer community and the queerphobic society. From the digitally published 14: An Anthology of Queer Art’s two volumes, five short stories are analysed regarding different forms of intimacies in queer men’s relationships. These queer contemporary fiction writers offer complex representations of queerness within Nigeria’s heteropatriarchal and queerphobic society that polices non-normative bodies through religion, culture and the law. Such literary texts, digital literary platforms and activism vitally provide queer Nigerians a progressive space to assert queer presence, voices lives and rights to educating and re-socialising their society towards humaneness. , Thesis (MA) -- Faculty of Humanities, Literary Studies in English, 2021
- Full Text:
- Date Issued: 2021-10-29
An investigation of the English language demands of mathematical texts on data handling used in intermediate phase mathematics
- Authors: Jones, Angela Peta
- Date: 2022-10-14
- Subjects: Mathematics Study and teaching (Elementary) South Africa , Middle school education South Africa , Information storage and retrieval systems Mathematics , Language complexity , Textbooks Readability , Language arts Correlation with content subjects South Africa , Content area reading South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/405259 , vital:70155
- Description: In the Intermediate Phase the majority of South African learners are transitioning from learning in their mother tongue to learning in English as well as from learning to read to reading to learn, and this is a major challenge. Textbooks are a key mediating artefact in the learning of mathematics and they present a challenge to the learner in terms of the language comprehension demands The data handling sections of mathematics textbooks are particularly dense in text. This is an important part of the mathematics curriculum as it is the beginning of statistical literacy learning. We need to be able to question, evaluate claims based on data, create arguments we can defend and use data meaningfully, it is thus crucial that learners acquire statistical literacy. This research sets out to examine the text in the data handling sections of four Intermediate Phase Mathematics book series in order to answer the following research question: What are the language comprehension demands of English mathematical texts on data handling that are used in South African Intermediate Phase Mathematics? The theories framing the study are Vygotsky’s sociocultural theory and Cummins’ second language acquisition theory. It is an interpretivist mixed method case study that takes the form of a document analysis.. The findings indicate that many units in the books analysed have a higher readability level than the grade level and will thus present a challenge to learners in terms of their ability to access the mathematical content. An analysis of the linguistic complexity revealed that the features contributing most to the complexity of the texts included words with seven or more letters, prepositional phrases, infinitives, complex verbs and complex/compound sentences. An examination of the non-textual elements revealed that most of them are accurate, connected, concise, contextual and these add to the comprehensibility although there were a few which could be possibly be distractors. It is hoped that the empirical findings of this study, will sensitise educators and publishers involved with the design of textbooks and workbooks to the type of language currently found and that they might give attention to the needs of English language learners when developing these texts. , Thesis (MEd) -- Faculty of Education, Education, 2022
- Full Text:
- Date Issued: 2022-10-14
- Authors: Jones, Angela Peta
- Date: 2022-10-14
- Subjects: Mathematics Study and teaching (Elementary) South Africa , Middle school education South Africa , Information storage and retrieval systems Mathematics , Language complexity , Textbooks Readability , Language arts Correlation with content subjects South Africa , Content area reading South Africa
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/405259 , vital:70155
- Description: In the Intermediate Phase the majority of South African learners are transitioning from learning in their mother tongue to learning in English as well as from learning to read to reading to learn, and this is a major challenge. Textbooks are a key mediating artefact in the learning of mathematics and they present a challenge to the learner in terms of the language comprehension demands The data handling sections of mathematics textbooks are particularly dense in text. This is an important part of the mathematics curriculum as it is the beginning of statistical literacy learning. We need to be able to question, evaluate claims based on data, create arguments we can defend and use data meaningfully, it is thus crucial that learners acquire statistical literacy. This research sets out to examine the text in the data handling sections of four Intermediate Phase Mathematics book series in order to answer the following research question: What are the language comprehension demands of English mathematical texts on data handling that are used in South African Intermediate Phase Mathematics? The theories framing the study are Vygotsky’s sociocultural theory and Cummins’ second language acquisition theory. It is an interpretivist mixed method case study that takes the form of a document analysis.. The findings indicate that many units in the books analysed have a higher readability level than the grade level and will thus present a challenge to learners in terms of their ability to access the mathematical content. An analysis of the linguistic complexity revealed that the features contributing most to the complexity of the texts included words with seven or more letters, prepositional phrases, infinitives, complex verbs and complex/compound sentences. An examination of the non-textual elements revealed that most of them are accurate, connected, concise, contextual and these add to the comprehensibility although there were a few which could be possibly be distractors. It is hoped that the empirical findings of this study, will sensitise educators and publishers involved with the design of textbooks and workbooks to the type of language currently found and that they might give attention to the needs of English language learners when developing these texts. , Thesis (MEd) -- Faculty of Education, Education, 2022
- Full Text:
- Date Issued: 2022-10-14
Molecular characterization of microbial communities in the Sundays and Swartkops estuaries impacted by anthropogenic activities
- Kgomokhumo, Tlhoafalang Evah
- Authors: Kgomokhumo, Tlhoafalang Evah
- Date: 2022-04-06
- Subjects: Microbial ecology South Africa Sundays Estuary (Eastern Cape) , Microbial ecology South Africa Swartkops River Estuary , Estuarine health Effect of human beings on South Africa Sundays Estuary (Eastern Cape) , Estuarine health Effect of human beings on South Africa Swartkops River Estuary , Microorganisms South Africa Sundays Estuary (Eastern Cape) Molecular aspects , Microorganisms South Africa Swartkops River Estuary Molecular aspects , Eutrophication South Africa Sundays Estuary (Eastern Cape) , Eutrophication South Africa Swartkops River Estuary , Algal blooms South Africa Sundays Estuary (Eastern Cape) , Algal blooms South Africa Swartkops River Estuary
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/290994 , vital:56806
- Description: Anthropogenic activities are of concern in estuarine systems as they are the main source of water degradation. Water pollution in estuaries is indicated by eutrophication and the presence of pathogens and bacterial indicators which affect biodiversity and energy flow. This study focused on two geographically linked estuaries, namely the Sundays and Swartkops Estuaries. The Sundays Estuary is primarily impacted by agricultural activities in the river catchment with increased nutrients levels, particularly of total oxidised nitrogen (TOxN), likely derived from these farming activities. In contrast, the Swartkops Estuary, which is heavily influenced by urban/industrial activities, reflected increased levels of phosphates likely from wastewater and sewage water contamination from residential areas, leaking pipes, and poorly managed sewage treatment plants. The central objective of this study was to assess microbial population profiles and diversity impacted by agricultural activities in Sundays Estuary and industrial/urban-influenced Swartkops Estuary using 16S and 18S rRNA gene metabarcoding. A distinct difference in eukaryotic composition and diversity was evident between the two sampling exercises in 2018 and 2019 in Sundays Estuary. The eutrophication of both the Sundays and Swartkops estuaries was evident in the repeated occurrences of bloom events. In the Sundays Estuary, a bloom of Heterosigma akashiwo was observed in 2018 whilst Cyclotella dominated the estuary in 2019. The Swartkops Estuary exhibited seasonal variation in phytoplankton composition with Bacillariophyceae blooms in the upper reaches of the estuary in summer and increased prevalence of Dinophyceae in spring. Bacterial taxonomic variation was also noted between the two contrasting estuaries. Although members of the Proteobacteria dominated both estuaries, Gammaproteobacteria were in increased abundance in Sundays Estuary while members of Alphaproteobacteria were in high relative abundance in the marine dominated Swartkops Estuary. Members of the Bacteroidetes were the second most abundant bacterial phylum in both estuaries. Bacterial indicators of agricultural anthropogenic impacts identified in Sundays Estuary included members of Sporichthyaceae, Erysipelotrichaceae, Nostocaceae, and NS11-12_marine_group while some taxa such as the Flavobacteriaceae, Cryomorphaceae, and Halieaceae reflected their capability in degrading the phytoplankton bloom biomass present in the estuary. The urban impacts on the Swartkops Estuary was reflected by the contamination of the estuary with potential pathogens including Aeromonas caviae, Vibrio fluvialis, Mycobacterium intracellulare, Vibrio cholerae, and Bacillus cereus. Bacterial community profiles of the major water inflow points into the Swartkops Estuary included members of the Burkholderiaceae, Rhodocyclaceae, Aeromonadaceae, and Arcobacteriaceae which are typically indicative of raw sewage contamination. The Motherwell canal, which runs through informal settlements, was the most polluted input source with high levels of anthropogenic nutrients and pathogenic bacteria. The Chatty river, which also runs through townships, recorded increased nutrient concentrations and low bacterial richness and diversity which was likely due to an Arthrospira bloom at the time of sampling. The overall results of this study identified sources of pollution in Sundays and Swartkops Estuaries and highlighted the impacts of anthropogenic inputs on microbial population profiles and diversity. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Kgomokhumo, Tlhoafalang Evah
- Date: 2022-04-06
- Subjects: Microbial ecology South Africa Sundays Estuary (Eastern Cape) , Microbial ecology South Africa Swartkops River Estuary , Estuarine health Effect of human beings on South Africa Sundays Estuary (Eastern Cape) , Estuarine health Effect of human beings on South Africa Swartkops River Estuary , Microorganisms South Africa Sundays Estuary (Eastern Cape) Molecular aspects , Microorganisms South Africa Swartkops River Estuary Molecular aspects , Eutrophication South Africa Sundays Estuary (Eastern Cape) , Eutrophication South Africa Swartkops River Estuary , Algal blooms South Africa Sundays Estuary (Eastern Cape) , Algal blooms South Africa Swartkops River Estuary
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/290994 , vital:56806
- Description: Anthropogenic activities are of concern in estuarine systems as they are the main source of water degradation. Water pollution in estuaries is indicated by eutrophication and the presence of pathogens and bacterial indicators which affect biodiversity and energy flow. This study focused on two geographically linked estuaries, namely the Sundays and Swartkops Estuaries. The Sundays Estuary is primarily impacted by agricultural activities in the river catchment with increased nutrients levels, particularly of total oxidised nitrogen (TOxN), likely derived from these farming activities. In contrast, the Swartkops Estuary, which is heavily influenced by urban/industrial activities, reflected increased levels of phosphates likely from wastewater and sewage water contamination from residential areas, leaking pipes, and poorly managed sewage treatment plants. The central objective of this study was to assess microbial population profiles and diversity impacted by agricultural activities in Sundays Estuary and industrial/urban-influenced Swartkops Estuary using 16S and 18S rRNA gene metabarcoding. A distinct difference in eukaryotic composition and diversity was evident between the two sampling exercises in 2018 and 2019 in Sundays Estuary. The eutrophication of both the Sundays and Swartkops estuaries was evident in the repeated occurrences of bloom events. In the Sundays Estuary, a bloom of Heterosigma akashiwo was observed in 2018 whilst Cyclotella dominated the estuary in 2019. The Swartkops Estuary exhibited seasonal variation in phytoplankton composition with Bacillariophyceae blooms in the upper reaches of the estuary in summer and increased prevalence of Dinophyceae in spring. Bacterial taxonomic variation was also noted between the two contrasting estuaries. Although members of the Proteobacteria dominated both estuaries, Gammaproteobacteria were in increased abundance in Sundays Estuary while members of Alphaproteobacteria were in high relative abundance in the marine dominated Swartkops Estuary. Members of the Bacteroidetes were the second most abundant bacterial phylum in both estuaries. Bacterial indicators of agricultural anthropogenic impacts identified in Sundays Estuary included members of Sporichthyaceae, Erysipelotrichaceae, Nostocaceae, and NS11-12_marine_group while some taxa such as the Flavobacteriaceae, Cryomorphaceae, and Halieaceae reflected their capability in degrading the phytoplankton bloom biomass present in the estuary. The urban impacts on the Swartkops Estuary was reflected by the contamination of the estuary with potential pathogens including Aeromonas caviae, Vibrio fluvialis, Mycobacterium intracellulare, Vibrio cholerae, and Bacillus cereus. Bacterial community profiles of the major water inflow points into the Swartkops Estuary included members of the Burkholderiaceae, Rhodocyclaceae, Aeromonadaceae, and Arcobacteriaceae which are typically indicative of raw sewage contamination. The Motherwell canal, which runs through informal settlements, was the most polluted input source with high levels of anthropogenic nutrients and pathogenic bacteria. The Chatty river, which also runs through townships, recorded increased nutrient concentrations and low bacterial richness and diversity which was likely due to an Arthrospira bloom at the time of sampling. The overall results of this study identified sources of pollution in Sundays and Swartkops Estuaries and highlighted the impacts of anthropogenic inputs on microbial population profiles and diversity. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2022
- Full Text:
- Date Issued: 2022-04-06
Academic or ‘zoombie’? Characterizing sleep quality, work and lifestyle behaviours among a cohort of South African academic staff during the Covid-19 pandemic
- Authors: Le Grange, Sarah-Ann
- Date: 2022-04-06
- Subjects: Sleep-wake cycle South Africa Eastern Cape , Sleep Physiological aspects , Lifestyles Health aspects South Africa Eastern Cape , COVID-19 Pandemic, 2020- Influence , Work environment Psychological aspects , Work environment Physiological aspects , College teachers Workload South Africa Eastern Cape , Pittsburgh Sleep Quality Index (PSQI)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/291099 , vital:56818
- Description: Working in academe is characterized by high work demands, long and late working hours and balancing multiple roles. This often leaves academic staff (interchangeably referred to as ‘academics’ and ‘staff’) with limited time to prioritize adequate rest and sleep. While sufficient sleep is important for general well-being and work performance, it may be important for academics given the cognitive and interactive nature of their work. However, limited research has characterized sleep behaviours and sleep quality in academic staff globally and specifically in South Africa (SA). Further, research shows that academics from different academic ranks and genders differ in their work experiences but less is known about whether these factors affect their sleep and lifestyle factors. Over and above the demands of academic work, the current study was conducted during COVID-19, which saw unprecedented change in workloads for academic staff due to online teaching and learning. Additionally, the pandemic has been associated with poorer sleep quality and lifestyle behaviours in the general population, but very few studies have explored this in the context of academics. Thus, this study aimed to characterize the sleep quality, work and lifestyle factors among academics from a university in the Eastern Cape province of SA and determine the effects of gender and academic rank on these measures. Additionally, the study aimed to determine the impact of COVID-19 on sleep and work-related factors of this group. This study adopted a cross-sectional design and made use of an online questionnaire that was distributed to all academics employed at the institution via email. The data collection occurred over an 8-week testing period between August and September of 2020. The questionnaire explored sociodemographic, work and lifestyle characteristics, while the characteristics of sleep and sleep quality were explored with the Pittsburgh Sleep Quality Index (PSQI). Additionally, an open-ended section was included to determine the impact of COVID-19-related changes on sleep and work. The questionnaire responses were analyzed with descriptive and inferential statistics and the open-ended questions were analyzed with thematic analyses. A total of 84 respondents completed the questionnaire. On average, sleep quality was poor (global score of 7.09 ± 3.8), the reported sleep duration was short (6.41 ± 1.06 hrs) and the group was classified as overweight according to median BMI (26.67 [23.8-2 29.45] kg/m2). Over a third (35.71%) of academic staff reported not meeting physical activity guidelines and reported using screens one hour prior to bed every night during the week (76.19%) and the weekend (67.88%). Staff also worked long total weekly work hours (54.25 ± 11). Female academics had a poorer sleep quality (p = 0.035), spent a longer time in bed (p = 0.04), experienced more bad dreams (p = <0.01), had their last serving of alcohol earlier (p = 0.04) and worked less weekday (p = 0.04) and less total weekly (p = 0.02) hours compared to male academics. Professorship-level academics were significantly older than junior- and senior-level academics (p = <0.01) while senior-level academics had a poorer PSQI compared to professorship-level academics (p = 0.03). The thematic analysis showed that home environment, neighbourhood noise, work and mental health were the main emerging factors that disturbed sleep. The thematic analysis showed that, in relation to the impact of COVID19, sleep schedules changed and sleep duration and sleep quality improved or got worse. Respondents reported their work hours increasing, work schedules becoming less routine while working from home, dealing with the challenges of working online and experiencing worry, stress and anxiety due to the pandemic. The study highlights that, in the context of lockdown and having to work and teach online from home, academics reported poor quality sleep and short sleep duration. Further, on average, the sample reported working extensive hours and unhealthy lifestyle behaviours. The sleep health, nature of work and overall lifestyles of academic staff deserves more research attention, given the importance of their work and the impact that inadequate sleep could have on academics’ health and work performance. Sleep quality was worse for females and mid-career academics, suggesting that their sleep quality may be at greater risk than other sub-groups. However, the reasons for these differences need to be explored in future studies. The findings contribute to the narrative that academe involves numerous demands and supports previous research that has suggested that academics’ sleep is insufficient. Furthermore, COVID-19 had an impact on staff’s sleep, with staff reporting changes in their sleep quality and duration. The pandemic impacted work of academics by presenting novel demands related to online teaching, intensifying demands overall and disrupting work routines. However, future research is needed to understand academics’ sleep behaviours, work and lifestyles, especially in South Africa. , Thesis (MSc) -- Faculty of Science, Human Kinetics and Ergonomics, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Le Grange, Sarah-Ann
- Date: 2022-04-06
- Subjects: Sleep-wake cycle South Africa Eastern Cape , Sleep Physiological aspects , Lifestyles Health aspects South Africa Eastern Cape , COVID-19 Pandemic, 2020- Influence , Work environment Psychological aspects , Work environment Physiological aspects , College teachers Workload South Africa Eastern Cape , Pittsburgh Sleep Quality Index (PSQI)
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/291099 , vital:56818
- Description: Working in academe is characterized by high work demands, long and late working hours and balancing multiple roles. This often leaves academic staff (interchangeably referred to as ‘academics’ and ‘staff’) with limited time to prioritize adequate rest and sleep. While sufficient sleep is important for general well-being and work performance, it may be important for academics given the cognitive and interactive nature of their work. However, limited research has characterized sleep behaviours and sleep quality in academic staff globally and specifically in South Africa (SA). Further, research shows that academics from different academic ranks and genders differ in their work experiences but less is known about whether these factors affect their sleep and lifestyle factors. Over and above the demands of academic work, the current study was conducted during COVID-19, which saw unprecedented change in workloads for academic staff due to online teaching and learning. Additionally, the pandemic has been associated with poorer sleep quality and lifestyle behaviours in the general population, but very few studies have explored this in the context of academics. Thus, this study aimed to characterize the sleep quality, work and lifestyle factors among academics from a university in the Eastern Cape province of SA and determine the effects of gender and academic rank on these measures. Additionally, the study aimed to determine the impact of COVID-19 on sleep and work-related factors of this group. This study adopted a cross-sectional design and made use of an online questionnaire that was distributed to all academics employed at the institution via email. The data collection occurred over an 8-week testing period between August and September of 2020. The questionnaire explored sociodemographic, work and lifestyle characteristics, while the characteristics of sleep and sleep quality were explored with the Pittsburgh Sleep Quality Index (PSQI). Additionally, an open-ended section was included to determine the impact of COVID-19-related changes on sleep and work. The questionnaire responses were analyzed with descriptive and inferential statistics and the open-ended questions were analyzed with thematic analyses. A total of 84 respondents completed the questionnaire. On average, sleep quality was poor (global score of 7.09 ± 3.8), the reported sleep duration was short (6.41 ± 1.06 hrs) and the group was classified as overweight according to median BMI (26.67 [23.8-2 29.45] kg/m2). Over a third (35.71%) of academic staff reported not meeting physical activity guidelines and reported using screens one hour prior to bed every night during the week (76.19%) and the weekend (67.88%). Staff also worked long total weekly work hours (54.25 ± 11). Female academics had a poorer sleep quality (p = 0.035), spent a longer time in bed (p = 0.04), experienced more bad dreams (p = <0.01), had their last serving of alcohol earlier (p = 0.04) and worked less weekday (p = 0.04) and less total weekly (p = 0.02) hours compared to male academics. Professorship-level academics were significantly older than junior- and senior-level academics (p = <0.01) while senior-level academics had a poorer PSQI compared to professorship-level academics (p = 0.03). The thematic analysis showed that home environment, neighbourhood noise, work and mental health were the main emerging factors that disturbed sleep. The thematic analysis showed that, in relation to the impact of COVID19, sleep schedules changed and sleep duration and sleep quality improved or got worse. Respondents reported their work hours increasing, work schedules becoming less routine while working from home, dealing with the challenges of working online and experiencing worry, stress and anxiety due to the pandemic. The study highlights that, in the context of lockdown and having to work and teach online from home, academics reported poor quality sleep and short sleep duration. Further, on average, the sample reported working extensive hours and unhealthy lifestyle behaviours. The sleep health, nature of work and overall lifestyles of academic staff deserves more research attention, given the importance of their work and the impact that inadequate sleep could have on academics’ health and work performance. Sleep quality was worse for females and mid-career academics, suggesting that their sleep quality may be at greater risk than other sub-groups. However, the reasons for these differences need to be explored in future studies. The findings contribute to the narrative that academe involves numerous demands and supports previous research that has suggested that academics’ sleep is insufficient. Furthermore, COVID-19 had an impact on staff’s sleep, with staff reporting changes in their sleep quality and duration. The pandemic impacted work of academics by presenting novel demands related to online teaching, intensifying demands overall and disrupting work routines. However, future research is needed to understand academics’ sleep behaviours, work and lifestyles, especially in South Africa. , Thesis (MSc) -- Faculty of Science, Human Kinetics and Ergonomics, 2022
- Full Text:
- Date Issued: 2022-04-06