Conceptualisations and pedagogical practices of academic literacy in Namibian higher education
- Authors: Julius, Lukas Homateni
- Date: 2021-04
- Subjects: Information literacy -- Study and teaching (Higher) -- Namibia , Academic writing -- Study and teaching -- Namibia , Qualitative research -- Methodology , Academic language -- Namibia , Information literacy -- Social aspects
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/177293 , vital:42807 , 10.21504/10962/177293
- Description: The purpose of this study was to investigate academic literacy development lecturers’ conceptualisations of academic literacy and resultant pedagogical practices in academic development courses at three different Higher Education Institutional types in Namibia. The research sites were a Traditional University, a University of Technology and a Comprehensive University. The focus was to understand the extent to which the academics’ conceptions of academic literacy and the resultant pedagogical practices in the academic development courses at these three Higher Education Institutions (HEIs) facilitate epistemological access into students’ chosen fields of study. Bernstein’s Pedagogical theory (1990), Genre theory (1996) and Halliday’s Systemic Functional Linguistics (1978) were used as the study’s theoretical lenses and analytical framework. An interpretative paradigm and a qualitative case study design were employed as the research approach. Semi-structured interviews, classroom observations and documentary evidence were used to generate data. Research findings revealed a common (mis)conception of the nature of academic literacy, the resultant inadequate learning support offered to students in the selected academic literacy development courses, and a clear divorcing of academic literacy interventions from the students’ ‘home’ or mainstream disciplines at the three HEIs. The participants understood academic literacy from an autonomous position as a set of generic skills which could be taught outside of mainstream classes. Moreover, findings revealed that this understanding impacted on the design and assessments of all the academic literacy courses across the three universities under study. The study calls for a context sensitive model through which academic literacy acquisition can be scaffolded to meet the discipline-specific epistemological needs of the students. , Elalakano lyehokololoningomwa lyomapekapeko ndika olyo okukonakona ehumithokomeho lyomikalo dhokulesha nokushanga meilongngo lyopombada (oAcademic Literaci) maaputudhilongi, okukonakona omafatululo giisimanintsa moAcademic Literaci osho wo okutala iizemo yomikalo dhayooloka dhokulonga noku ilonga iilongwa yayooloka miiputudhilo yelongo lyopombada moNamibia. Omapekapeko ngaka oga li ga ningilwa miiputudhilo yomaukwatya ta ga landula; Oshiputudhiilo shopamudhigululwakalo, Oshiputudhilo shopaunongononi, nOshiputudilo shomailongo gaandjakana. Oshintsa shopokati shomapekapeko ngaka osho okuuva ko ondodo yowino osho wo euveko lyoAcademic Literaci maaputudhilongi nonkene euveko nontseyo ndjika tayi longithwa oku eta oshizemo tashi humitha komeho euveko lyopombanda lyaalongwa yomailongo geewino dhayooloka miiputudhilo itatu yelongo lyopombanda; shino otashi kwathele aalongwa yamone ontseyo ndjoka tayi ya kwathele meilongo lyawo. Omapekapeko ngano oga longitha omadhiladhiloukithi (eetheori) ga Bernstein’s Pedagogical theori (1990), Genre theori (1996) na Halliday’s Systemic Functional Linguistics theori (1978), mokufatulula nokundjandjukununa iizemo yomapekapeko. Omodela yokukonakona iizemo yongushu tayi ziilile maakonakonwa, oya tala ekonakono ndika onga oshintsa shopokati, oyo ya longithwa, opo ku monike uuyelele wothaathaa. Omikalo dha longifwa mokukonakona noku gongela uuyelele momapekapeko ngano ongaashi, eenkundathana dhayaali, omatalelo geetundi oshoyo omakonakono giinyanyangidhwa tayi kwandjangele nepekapeko ndika. Iizedjemo yepekapeko ndika otayi ulike kutya opena engwangwano montseyo nenge mefatululo lyuukwatya woAcademic Literaci, shoka sha eta enkundipalo meyambidhidho hali pewa aalongwa miilongwa yeewino dhayooloka. Shika otashi ulike kutya kapena etsokumwe pokati keenkambadhala tadhi ningwa kaapudhilongi dhokulonga oAcademic Litraci miilongwa ya yooloka mbyoka tayi ilongelwa kaalongwa miiputudhilo itatu yopombada. iizemmo yepekapeko olyo tuu mdika oya ulike wo kutya aalongwa mboka yaza komailongo ga yooloka oha yi ilongo nuudhigu opo ya pondole ondondo yomadhiladhilo gopombanda meilongo lyuukumwe. Mokukonakona euveko lyoAcademic Literaci, epekapeko ndika olya ndhindhilike kutya aakuthimbinga oyena euveko lyankundipala lyoterma ‘Academic Literaci,’ ano ya nyengwa okukwatakanitha oohedi dhopetameko ndhoka dhina oku ilongwa meikalekelo - ano pondje yiilongwa ikwao. Oshikwao, iizemo oya ulike kutya euveko ndika otali nwetha mo etungepo lyoAcademic Literaci onga oshilongwa, osho wo omakonakono gasho miiputudilo yombombanda itatu yakwatelwa momapekapeko. Hugunina, epekapeko ndika otali ulike/gandja oshiholelwa shomodela ndjoka oAcademic literacy tai vulu okulongwa opo yi kwatelemo eilongo lyiikwatelela kiilongwa osho yo komaitaalo nokeempumbwe dhaalongwa miiputudhilo yopombabda. , Thesis (PhD) -- Faculty of Education, Centre for Higher Education Research, Teaching and Learning (CHERTL), 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Julius, Lukas Homateni
- Date: 2021-04
- Subjects: Information literacy -- Study and teaching (Higher) -- Namibia , Academic writing -- Study and teaching -- Namibia , Qualitative research -- Methodology , Academic language -- Namibia , Information literacy -- Social aspects
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/177293 , vital:42807 , 10.21504/10962/177293
- Description: The purpose of this study was to investigate academic literacy development lecturers’ conceptualisations of academic literacy and resultant pedagogical practices in academic development courses at three different Higher Education Institutional types in Namibia. The research sites were a Traditional University, a University of Technology and a Comprehensive University. The focus was to understand the extent to which the academics’ conceptions of academic literacy and the resultant pedagogical practices in the academic development courses at these three Higher Education Institutions (HEIs) facilitate epistemological access into students’ chosen fields of study. Bernstein’s Pedagogical theory (1990), Genre theory (1996) and Halliday’s Systemic Functional Linguistics (1978) were used as the study’s theoretical lenses and analytical framework. An interpretative paradigm and a qualitative case study design were employed as the research approach. Semi-structured interviews, classroom observations and documentary evidence were used to generate data. Research findings revealed a common (mis)conception of the nature of academic literacy, the resultant inadequate learning support offered to students in the selected academic literacy development courses, and a clear divorcing of academic literacy interventions from the students’ ‘home’ or mainstream disciplines at the three HEIs. The participants understood academic literacy from an autonomous position as a set of generic skills which could be taught outside of mainstream classes. Moreover, findings revealed that this understanding impacted on the design and assessments of all the academic literacy courses across the three universities under study. The study calls for a context sensitive model through which academic literacy acquisition can be scaffolded to meet the discipline-specific epistemological needs of the students. , Elalakano lyehokololoningomwa lyomapekapeko ndika olyo okukonakona ehumithokomeho lyomikalo dhokulesha nokushanga meilongngo lyopombada (oAcademic Literaci) maaputudhilongi, okukonakona omafatululo giisimanintsa moAcademic Literaci osho wo okutala iizemo yomikalo dhayooloka dhokulonga noku ilonga iilongwa yayooloka miiputudhilo yelongo lyopombada moNamibia. Omapekapeko ngaka oga li ga ningilwa miiputudhilo yomaukwatya ta ga landula; Oshiputudhiilo shopamudhigululwakalo, Oshiputudhilo shopaunongononi, nOshiputudilo shomailongo gaandjakana. Oshintsa shopokati shomapekapeko ngaka osho okuuva ko ondodo yowino osho wo euveko lyoAcademic Literaci maaputudhilongi nonkene euveko nontseyo ndjika tayi longithwa oku eta oshizemo tashi humitha komeho euveko lyopombanda lyaalongwa yomailongo geewino dhayooloka miiputudhilo itatu yelongo lyopombanda; shino otashi kwathele aalongwa yamone ontseyo ndjoka tayi ya kwathele meilongo lyawo. Omapekapeko ngano oga longitha omadhiladhiloukithi (eetheori) ga Bernstein’s Pedagogical theori (1990), Genre theori (1996) na Halliday’s Systemic Functional Linguistics theori (1978), mokufatulula nokundjandjukununa iizemo yomapekapeko. Omodela yokukonakona iizemo yongushu tayi ziilile maakonakonwa, oya tala ekonakono ndika onga oshintsa shopokati, oyo ya longithwa, opo ku monike uuyelele wothaathaa. Omikalo dha longifwa mokukonakona noku gongela uuyelele momapekapeko ngano ongaashi, eenkundathana dhayaali, omatalelo geetundi oshoyo omakonakono giinyanyangidhwa tayi kwandjangele nepekapeko ndika. Iizedjemo yepekapeko ndika otayi ulike kutya opena engwangwano montseyo nenge mefatululo lyuukwatya woAcademic Literaci, shoka sha eta enkundipalo meyambidhidho hali pewa aalongwa miilongwa yeewino dhayooloka. Shika otashi ulike kutya kapena etsokumwe pokati keenkambadhala tadhi ningwa kaapudhilongi dhokulonga oAcademic Litraci miilongwa ya yooloka mbyoka tayi ilongelwa kaalongwa miiputudhilo itatu yopombada. iizemmo yepekapeko olyo tuu mdika oya ulike wo kutya aalongwa mboka yaza komailongo ga yooloka oha yi ilongo nuudhigu opo ya pondole ondondo yomadhiladhilo gopombanda meilongo lyuukumwe. Mokukonakona euveko lyoAcademic Literaci, epekapeko ndika olya ndhindhilike kutya aakuthimbinga oyena euveko lyankundipala lyoterma ‘Academic Literaci,’ ano ya nyengwa okukwatakanitha oohedi dhopetameko ndhoka dhina oku ilongwa meikalekelo - ano pondje yiilongwa ikwao. Oshikwao, iizemo oya ulike kutya euveko ndika otali nwetha mo etungepo lyoAcademic Literaci onga oshilongwa, osho wo omakonakono gasho miiputudilo yombombanda itatu yakwatelwa momapekapeko. Hugunina, epekapeko ndika otali ulike/gandja oshiholelwa shomodela ndjoka oAcademic literacy tai vulu okulongwa opo yi kwatelemo eilongo lyiikwatelela kiilongwa osho yo komaitaalo nokeempumbwe dhaalongwa miiputudhilo yopombabda. , Thesis (PhD) -- Faculty of Education, Centre for Higher Education Research, Teaching and Learning (CHERTL), 2021
- Full Text:
- Date Issued: 2021-04
Orchid mycorrhizal and endophytic fungal diversity of three co-occurring terrestrial orchids in the large African genus Disa (Orchidaceae)
- Khambule, Nondumiso Venessia
- Authors: Khambule, Nondumiso Venessia
- Date: 2020
- Subjects: Orchids South Africa , Mycorrhizal fungi South Africa , Endomycorrhizas South Africa , Endophytes , Orchids Roots
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/163341 , vital:41030
- Description: Orchids (in the family Orchidaceous) are one of the richest plant families and approximately 500 species are found in South Africa. A number of orchid species are found on disturbed areas and many of the terrestrial species grow in poor soils with low mineral nutrient availability. Most orchid species are thought to be associated with mycorrhizal fungi for germination and mycorrhiza provides nutrients for the survival of adult plants. The aim of this study was to select Orchidaceous plant species and to isolate, identify and characterize the orchid endophytes and assess these isolates for potential antimicrobial and enzymatic activities Isa is the largest genus in South Africa and three Disa species co-occurring in a small geographical area were selected. These included Disa bracteata, D. cornuta and D. polygonoides which span three sections of the genus. Roots were stained to confirm the mycorrhizal status of the Disa species. Mycorrhizal pelotons structures were microscopically observed inside root cells. The presence of pelotons is indictive of mycorrhizal fungal interactions within the orchid roots and areas associated with the site of nutrient exchange between plant and fungus. The presence of pelotons, however, does not give n indication of the fungal species involved. The endophytes were successfully isolated in pure cultures on potato dextrose agar (PDA). All slow growing isolates were selected, and further molecular identification undertaken; DNA was extracted, and PCR amplified using internal transcribed spacer (ITS1F and ITS4) fungal primers. The amplified products were then sequenced and analysed by comparison to sequences in the GenBank database. Trichoderma, Penicillium, Metapochonia, Talaromyces, Oidiodendron Neopestalotiopsis, and Chaetomium were identified from these sequences. The presence of other fungal root endophytes was suspected despite the rigorous surface sterilization procedure used. The primers used to amplify the ITS region are the universal barcoding primers which are specific to fungi. ITS1F is one of the primers designed to amplify a broad range of fungi. DNA was extracted from orchid roots and amplicons were cloned into a pGEMT plasmid vector. Individual clones were sequenced and aligned with Mega software and compared to sequences in the GenBank and UNITE database. Based on percentage sequence identity, unidentified Tulasnella species, Tullasnela colaspora, and various Ascomycota endophytes were identified as contributing to the endophytic root fungal diversity of the selected Disa species. The Disa species investigated in this study were associated with several soil endophytes. D. bracteata, D. polygonoides were collected from the same site along the road verge which is regarded as being disturbed. Based on both culture – dependent and independent techniques employed Oidiodendron was found associated with both species. Antimicrobial activity was determined using a well diffusion method using extracts from the isolated fungi against the bacterial isolates Bacillus cereus, Staphylococcus aureus, Escherichia coli and Pseudomonas puptida. Most of the isolated fungi showed at least one potential inhibition effect against one of the bacterial isolates. The extracts that showed potential antimicrobial activity could be further screened to determine the compounds produced as secondary metabolites using techniques such as LC-MS Enzymatic activities of protease, cellulose and amylase were determined using solid media amended with milk protein, carboxymethylcellulose (CMC) and starch. The majority of fungal isolates tested positive with amylase and cellulose with only a few fungal isolates testing positive for protease activity. Broth cultures containing CMC and starch were shown to enhance biomass production in approximately 40 % of the fungal isolates. Degradation of the substrates is required in order to provide carbon to the fungus under test in order to optimize fungal growth as well as to gain insight into their ecological role. Enzyme activity was evident particularly when cellulose and starch were provided as substrates. All the fungal isolates tested grew on the amended medium, with 40% of the isolates preferring to utilize CMC and/or starch, indicating the ability of these fungi to utilize various resources for carbon acquisitions. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2020
- Full Text:
- Date Issued: 2020
- Authors: Khambule, Nondumiso Venessia
- Date: 2020
- Subjects: Orchids South Africa , Mycorrhizal fungi South Africa , Endomycorrhizas South Africa , Endophytes , Orchids Roots
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/163341 , vital:41030
- Description: Orchids (in the family Orchidaceous) are one of the richest plant families and approximately 500 species are found in South Africa. A number of orchid species are found on disturbed areas and many of the terrestrial species grow in poor soils with low mineral nutrient availability. Most orchid species are thought to be associated with mycorrhizal fungi for germination and mycorrhiza provides nutrients for the survival of adult plants. The aim of this study was to select Orchidaceous plant species and to isolate, identify and characterize the orchid endophytes and assess these isolates for potential antimicrobial and enzymatic activities Isa is the largest genus in South Africa and three Disa species co-occurring in a small geographical area were selected. These included Disa bracteata, D. cornuta and D. polygonoides which span three sections of the genus. Roots were stained to confirm the mycorrhizal status of the Disa species. Mycorrhizal pelotons structures were microscopically observed inside root cells. The presence of pelotons is indictive of mycorrhizal fungal interactions within the orchid roots and areas associated with the site of nutrient exchange between plant and fungus. The presence of pelotons, however, does not give n indication of the fungal species involved. The endophytes were successfully isolated in pure cultures on potato dextrose agar (PDA). All slow growing isolates were selected, and further molecular identification undertaken; DNA was extracted, and PCR amplified using internal transcribed spacer (ITS1F and ITS4) fungal primers. The amplified products were then sequenced and analysed by comparison to sequences in the GenBank database. Trichoderma, Penicillium, Metapochonia, Talaromyces, Oidiodendron Neopestalotiopsis, and Chaetomium were identified from these sequences. The presence of other fungal root endophytes was suspected despite the rigorous surface sterilization procedure used. The primers used to amplify the ITS region are the universal barcoding primers which are specific to fungi. ITS1F is one of the primers designed to amplify a broad range of fungi. DNA was extracted from orchid roots and amplicons were cloned into a pGEMT plasmid vector. Individual clones were sequenced and aligned with Mega software and compared to sequences in the GenBank and UNITE database. Based on percentage sequence identity, unidentified Tulasnella species, Tullasnela colaspora, and various Ascomycota endophytes were identified as contributing to the endophytic root fungal diversity of the selected Disa species. The Disa species investigated in this study were associated with several soil endophytes. D. bracteata, D. polygonoides were collected from the same site along the road verge which is regarded as being disturbed. Based on both culture – dependent and independent techniques employed Oidiodendron was found associated with both species. Antimicrobial activity was determined using a well diffusion method using extracts from the isolated fungi against the bacterial isolates Bacillus cereus, Staphylococcus aureus, Escherichia coli and Pseudomonas puptida. Most of the isolated fungi showed at least one potential inhibition effect against one of the bacterial isolates. The extracts that showed potential antimicrobial activity could be further screened to determine the compounds produced as secondary metabolites using techniques such as LC-MS Enzymatic activities of protease, cellulose and amylase were determined using solid media amended with milk protein, carboxymethylcellulose (CMC) and starch. The majority of fungal isolates tested positive with amylase and cellulose with only a few fungal isolates testing positive for protease activity. Broth cultures containing CMC and starch were shown to enhance biomass production in approximately 40 % of the fungal isolates. Degradation of the substrates is required in order to provide carbon to the fungus under test in order to optimize fungal growth as well as to gain insight into their ecological role. Enzyme activity was evident particularly when cellulose and starch were provided as substrates. All the fungal isolates tested grew on the amended medium, with 40% of the isolates preferring to utilize CMC and/or starch, indicating the ability of these fungi to utilize various resources for carbon acquisitions. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2020
- Full Text:
- Date Issued: 2020
Decorated titania fibers as photocatalysts for hydrogen generation and organic matter degradation
- Mapukata, Sivuyisiwe, Hainer, Andrew S, Lanterna, Anabel E, Scaiano, Juan C, Nyokong, Tebello
- Authors: Mapukata, Sivuyisiwe , Hainer, Andrew S , Lanterna, Anabel E , Scaiano, Juan C , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186573 , vital:44513 , xlink:href="https://doi.org/10.1016/j.jphotochem.2019.112185"
- Description: Heterogenous photocatalysts based on electrospun fibers composed of polyvinylpyrrolidone and titanium propoxide were prepared and heated at 500, 750 and 950 °C to obtain anatase and rutile fibers. The fibers were then decorated with Pd and Co nanoparticles as well as a symmetrical zinc phthalocyanine (Pc). The fibrous materials obtained have a paper-like macroscopic appearance allowing for easy handling and separation. The photocatalytic activities of the new materials were evaluated for the generation of H2 upon UV (368 nm) or visible (630 nm) light excitation. Depending on the heat treatment or the post-synthetic decoration method, the materials show higher, or similar, activity compared to P25-TiO2, with superior ease of separation. The catalysts showed ability to degrade organic matter, with MeOH used as a model compound. This is of considerable importance for potential water treatment applications that will require flow-compatible materials.
- Full Text:
- Date Issued: 2020
- Authors: Mapukata, Sivuyisiwe , Hainer, Andrew S , Lanterna, Anabel E , Scaiano, Juan C , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186573 , vital:44513 , xlink:href="https://doi.org/10.1016/j.jphotochem.2019.112185"
- Description: Heterogenous photocatalysts based on electrospun fibers composed of polyvinylpyrrolidone and titanium propoxide were prepared and heated at 500, 750 and 950 °C to obtain anatase and rutile fibers. The fibers were then decorated with Pd and Co nanoparticles as well as a symmetrical zinc phthalocyanine (Pc). The fibrous materials obtained have a paper-like macroscopic appearance allowing for easy handling and separation. The photocatalytic activities of the new materials were evaluated for the generation of H2 upon UV (368 nm) or visible (630 nm) light excitation. Depending on the heat treatment or the post-synthetic decoration method, the materials show higher, or similar, activity compared to P25-TiO2, with superior ease of separation. The catalysts showed ability to degrade organic matter, with MeOH used as a model compound. This is of considerable importance for potential water treatment applications that will require flow-compatible materials.
- Full Text:
- Date Issued: 2020
Formulation and characterisation of a combination captopril and hydrochlorothiazide microparticulate dosage form for paediatric use
- Chikukwa, Mellisa Tafadzwa Ruramai
- Authors: Chikukwa, Mellisa Tafadzwa Ruramai
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/163216 , vital:41019 , doi:10.21504/10962/163216
- Description: Thesis (PhD)--Rhodes University, Pharmacy Faculty, Department of Pharmaceutics, 2020
- Full Text:
- Date Issued: 2020
- Authors: Chikukwa, Mellisa Tafadzwa Ruramai
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/163216 , vital:41019 , doi:10.21504/10962/163216
- Description: Thesis (PhD)--Rhodes University, Pharmacy Faculty, Department of Pharmaceutics, 2020
- Full Text:
- Date Issued: 2020
Softboi
- Authors: Mall, Shireen
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MA
- Identifier: http://hdl.handle.net/10962/164373 , vital:41113
- Description: Thesis (MA)--Rhodes University, Faculty of Humanities, School of Languages, 2020
- Full Text:
- Date Issued: 2020
- Authors: Mall, Shireen
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MA
- Identifier: http://hdl.handle.net/10962/164373 , vital:41113
- Description: Thesis (MA)--Rhodes University, Faculty of Humanities, School of Languages, 2020
- Full Text:
- Date Issued: 2020
Nano-biomimetic drug delivery vehicles: Potential approaches for COVID-19 treatment
- Witika, Bwalya A, Makoni, Pedzisai A, Mweetwa, Larry L, Ntemi, Pascal V, Chikukwa, Mellisa T R, Matafwali, Scott K, Mwila, Chiluba, Mudenda, Steward, Katandula, Jonathan, Walker, Roderick B
- Authors: Witika, Bwalya A , Makoni, Pedzisai A , Mweetwa, Larry L , Ntemi, Pascal V , Chikukwa, Mellisa T R , Matafwali, Scott K , Mwila, Chiluba , Mudenda, Steward , Katandula, Jonathan , Walker, Roderick B
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183440 , vital:43991 , xlink:href="https://doi.org/10.3390/molecules25245952"
- Description: The current COVID-19 pandemic has tested the resolve of the global community with more than 35 million infections worldwide and numbers increasing with no cure or vaccine available to date. Nanomedicines have an advantage of providing enhanced permeability and retention and have been extensively studied as targeted drug delivery strategies for the treatment of different disease. The role of monocytes, erythrocytes, thrombocytes, and macrophages in diseases, including infectious and inflammatory diseases, cancer, and atherosclerosis, are better understood and have resulted in improved strategies for targeting and in some instances mimicking these cell types to improve therapeutic outcomes. Consequently, these primary cell types can be exploited for the purposes of serving as a "Trojan horse" for targeted delivery to identified organs and sites of inflammation. State of the art and potential utilization of nanocarriers such as nanospheres/nanocapsules, nanocrystals, liposomes, solid lipid nanoparticles/nano-structured lipid carriers, dendrimers, and nanosponges for biomimicry and/or targeted delivery of bioactives to cells are reported herein and their potential use in the treatment of COVID-19 infections discussed. Physicochemical properties, viz., hydrophilicity, particle shape, surface charge, composition, concentration, the use of different target-specific ligands on the surface of carriers, and the impact on carrier efficacy and specificity are also discussed.
- Full Text:
- Date Issued: 2020
- Authors: Witika, Bwalya A , Makoni, Pedzisai A , Mweetwa, Larry L , Ntemi, Pascal V , Chikukwa, Mellisa T R , Matafwali, Scott K , Mwila, Chiluba , Mudenda, Steward , Katandula, Jonathan , Walker, Roderick B
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/183440 , vital:43991 , xlink:href="https://doi.org/10.3390/molecules25245952"
- Description: The current COVID-19 pandemic has tested the resolve of the global community with more than 35 million infections worldwide and numbers increasing with no cure or vaccine available to date. Nanomedicines have an advantage of providing enhanced permeability and retention and have been extensively studied as targeted drug delivery strategies for the treatment of different disease. The role of monocytes, erythrocytes, thrombocytes, and macrophages in diseases, including infectious and inflammatory diseases, cancer, and atherosclerosis, are better understood and have resulted in improved strategies for targeting and in some instances mimicking these cell types to improve therapeutic outcomes. Consequently, these primary cell types can be exploited for the purposes of serving as a "Trojan horse" for targeted delivery to identified organs and sites of inflammation. State of the art and potential utilization of nanocarriers such as nanospheres/nanocapsules, nanocrystals, liposomes, solid lipid nanoparticles/nano-structured lipid carriers, dendrimers, and nanosponges for biomimicry and/or targeted delivery of bioactives to cells are reported herein and their potential use in the treatment of COVID-19 infections discussed. Physicochemical properties, viz., hydrophilicity, particle shape, surface charge, composition, concentration, the use of different target-specific ligands on the surface of carriers, and the impact on carrier efficacy and specificity are also discussed.
- Full Text:
- Date Issued: 2020
Development and assessment of a fixed dose combination of perindopril arginine and indapamide loaded microparticles
- Authors: Mandava, Tavonga Tyomai
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MSc
- Identifier: http://hdl.handle.net/10962/164413 , vital:41116
- Description: Thesis (MSc)--Rhodes University, Faculty of Pharmacy, Pharmaceutics, 2020
- Full Text:
- Date Issued: 2020
- Authors: Mandava, Tavonga Tyomai
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MSc
- Identifier: http://hdl.handle.net/10962/164413 , vital:41116
- Description: Thesis (MSc)--Rhodes University, Faculty of Pharmacy, Pharmaceutics, 2020
- Full Text:
- Date Issued: 2020
An evaluation of the cytotoxic activities of novel artemisinin derivatives: towards targeted therapies for triple-negative breast cancers (TNBC)
- Authors: Kajewole, Deborah Ifeoluwa
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/163329 , vital:41029 , doi:10.21504/10962/163329
- Description: Thesis (PhD)--Rhodes University, Faculty of Science, Biochemistry and Microbiology, 2020.
- Full Text:
- Date Issued: 2020
- Authors: Kajewole, Deborah Ifeoluwa
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/163329 , vital:41029 , doi:10.21504/10962/163329
- Description: Thesis (PhD)--Rhodes University, Faculty of Science, Biochemistry and Microbiology, 2020.
- Full Text:
- Date Issued: 2020
Editorial for Special Issue: Education for Sustainability in a Time of Crises
- Authors: Rosenberg, Eureta
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/370533 , vital:66352 , xlink:href="10.4314/sajee.v36i1.1"
- Description: There is an old and still popular saying that a crisis is an opportunity for change. The Chinese symbol for crisis is translated in Wikipedia as “danger at a point of juncture”. In the year 2020, first China and then the rest of humanity have been presented with a monumental crisis: a new and lethal virus that spread fast and far, causing actions and reactions, with dramatic consequences for social and economic life around the globe. Rebecca Solnit wrote of another crisis in her book Hope in the Dark: The Untold Story of People Power. In Grounds for Hope, a foreword to the 2015 edition (p.2), she stated: “This is an extraordinary time full of vital, transformative movements, that could not be foreseen. It’s also a nightmarish time. Full engagement requires the ability to perceive both.”.
- Full Text:
- Date Issued: 2020
- Authors: Rosenberg, Eureta
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/370533 , vital:66352 , xlink:href="10.4314/sajee.v36i1.1"
- Description: There is an old and still popular saying that a crisis is an opportunity for change. The Chinese symbol for crisis is translated in Wikipedia as “danger at a point of juncture”. In the year 2020, first China and then the rest of humanity have been presented with a monumental crisis: a new and lethal virus that spread fast and far, causing actions and reactions, with dramatic consequences for social and economic life around the globe. Rebecca Solnit wrote of another crisis in her book Hope in the Dark: The Untold Story of People Power. In Grounds for Hope, a foreword to the 2015 edition (p.2), she stated: “This is an extraordinary time full of vital, transformative movements, that could not be foreseen. It’s also a nightmarish time. Full engagement requires the ability to perceive both.”.
- Full Text:
- Date Issued: 2020
CO2-induced woody thickening depends strongly on interacting abiotic and biotic factors
- Authors: Raubenheimer, Sarah Lynn
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/164646 , vital:41151 , doi:10.21504/10962/164646
- Description: Thesis (PhD)--Rhodes University, Faculty of Science, Botany, 2020
- Full Text:
- Date Issued: 2020
- Authors: Raubenheimer, Sarah Lynn
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/164646 , vital:41151 , doi:10.21504/10962/164646
- Description: Thesis (PhD)--Rhodes University, Faculty of Science, Botany, 2020
- Full Text:
- Date Issued: 2020
Enhancement of photodynamic antimicrobialtherapy through the use of cationic indium porphyrin conjugated to Ag/CuFe2O4 nanoparticles
- Makola, Collen L, Managa, Muthumuni, Nyokong, Tebello
- Authors: Makola, Collen L , Managa, Muthumuni , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186233 , vital:44475 , xlink:href="https://doi.org/10.1016/j.pdpdt.2020.101736"
- Description: Photodynamic antimicrobial chemotherapy (PACT) is being actively researched as a possible alternative for antimicrobial agents. This study focuses on the application of neutral indium 5-p-carboxyphenyl-10-15-20-(tri-4-pyridyl)porphyrin and cationic indium 5-p-carboxyphenyl-10-15-20-(tris-4-methylpyridyl)-porphyrin triiodide conjugated to 6-mercapo-1-hexanol functionalized Ag/CuFe2O4 magnetic nanoparticles for photo-inactivation of S. aureus bacteria. Comparative studies were done on quaternized and unquaternized indium porphyrin complexes conjugated to Ag/CuFe2O4, where log reduction of 9.27 was obtained for quaternized conjugate and 0.83 for unquaternized conjugate.
- Full Text:
- Date Issued: 2020
- Authors: Makola, Collen L , Managa, Muthumuni , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186233 , vital:44475 , xlink:href="https://doi.org/10.1016/j.pdpdt.2020.101736"
- Description: Photodynamic antimicrobial chemotherapy (PACT) is being actively researched as a possible alternative for antimicrobial agents. This study focuses on the application of neutral indium 5-p-carboxyphenyl-10-15-20-(tri-4-pyridyl)porphyrin and cationic indium 5-p-carboxyphenyl-10-15-20-(tris-4-methylpyridyl)-porphyrin triiodide conjugated to 6-mercapo-1-hexanol functionalized Ag/CuFe2O4 magnetic nanoparticles for photo-inactivation of S. aureus bacteria. Comparative studies were done on quaternized and unquaternized indium porphyrin complexes conjugated to Ag/CuFe2O4, where log reduction of 9.27 was obtained for quaternized conjugate and 0.83 for unquaternized conjugate.
- Full Text:
- Date Issued: 2020
Direct nonlinear optical absorption measurements of asymmetrical zinc (II) phthalocyanine when covalently linked to semiconductor quantum dots
- Mgidlana, Sithi, Sen, Pinar, Nyokong, Tebello
- Authors: Mgidlana, Sithi , Sen, Pinar , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186056 , vital:44459 , xlink:href="https://doi.org/10.1016/j.molstruc.2020.128729"
- Description: We report on nonlinear optical properties of tris[(4-tert-butyl)-2-thio (phenyl)acetic acid (1) and tris(dimethyl-5-(3,4-phenoxy) isophthalate (2) phthalocyaninato zinc (II) complexes. The synthesized complexes were covalently conjugated to glutathione-capped CdTe/ZnSe/ZnO quantum dots. We observed an increase in triplet quantum yield with corresponding decrease in fluorescence quantum yield of conjugates compared to Pc complexes alone. Z-scan technique was employed to experimentally test the nonlinear optical response of complexes and nanoconjugates in solution at laser excitation wavelength of 532 nm with 7 ns pulse. Nonlinear absorption coefficient, third-order optical susceptibility and optical limiting threshold of the materials were obtained from the Z-scan data. The nonlinear absorption parameters improved in the presence of CdTe/ZnSe/ZnO, with 1 and 1-CdTe/ZnSe/ZnO, giving the best results due to the presence of electron donating substituents.
- Full Text:
- Date Issued: 2020
- Authors: Mgidlana, Sithi , Sen, Pinar , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186056 , vital:44459 , xlink:href="https://doi.org/10.1016/j.molstruc.2020.128729"
- Description: We report on nonlinear optical properties of tris[(4-tert-butyl)-2-thio (phenyl)acetic acid (1) and tris(dimethyl-5-(3,4-phenoxy) isophthalate (2) phthalocyaninato zinc (II) complexes. The synthesized complexes were covalently conjugated to glutathione-capped CdTe/ZnSe/ZnO quantum dots. We observed an increase in triplet quantum yield with corresponding decrease in fluorescence quantum yield of conjugates compared to Pc complexes alone. Z-scan technique was employed to experimentally test the nonlinear optical response of complexes and nanoconjugates in solution at laser excitation wavelength of 532 nm with 7 ns pulse. Nonlinear absorption coefficient, third-order optical susceptibility and optical limiting threshold of the materials were obtained from the Z-scan data. The nonlinear absorption parameters improved in the presence of CdTe/ZnSe/ZnO, with 1 and 1-CdTe/ZnSe/ZnO, giving the best results due to the presence of electron donating substituents.
- Full Text:
- Date Issued: 2020
Synthesis of peptidomimetic compounds as HIV-1 protease inhibitors
- Authors: Kayembe, Jean-Pierre
- Date: 2020
- Subjects: Protease inhibitors , HIV (Viruses) , HIV infections Treatment , Peptidomimetics
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/124397 , vital:35604 , DOI https://dx.doi.org/10.21504/10962/124397
- Description: This research project has involved the design, synthesis and evaluation of novel peptidomimetics compounds as HIV-1 protease inhibitors. Here is presented one-step, two-step and three-step syntheses and the in vitro bio-assay studies of a series of fully characterized peptidomimetics as HIV-1 protease inhibitors candidate using the shortest and most cost effective synthetic routes. The first series of compounds were accessed via a synthetic elaboration of Morita-Baylis-Hillman adducts by a Michael addition with benzylamine, proline or glycine esters to afford a series of β-amino-β’-hydroxycarboxylate esters in moderate to good yields. Base-catalyzed cyclization of non-benzylated aza-Michael adducts afforded a series of coumarin-3-hydroxy-2-methylenepropanoate esters in moderate yields. The uncatalyzed direct amidation of diethyl tartrate/tartaric acid and tartaric acid osazone with selected amines/amino acids afforded a series of C2-symmetrical and unsymmetrical 1,2-dihydroxycarboxylates in moderate to very high yields. All the synthesized compounds were fully characterized using spectroscopic techniques. These conjugates, designed as potential HIV-1 inhibitors, were tested against the HIV-1 protease enzyme. A number of these ligands have exhibited inhibition levels and IC50 values comparable to ritonavir, permitting, therefore, their identification as lead compounds for the development of novel inhibitors. , Thesis (PhD) -- Faculty of Science, Chemistry, 2020
- Full Text: false
- Date Issued: 2020
- Authors: Kayembe, Jean-Pierre
- Date: 2020
- Subjects: Protease inhibitors , HIV (Viruses) , HIV infections Treatment , Peptidomimetics
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/124397 , vital:35604 , DOI https://dx.doi.org/10.21504/10962/124397
- Description: This research project has involved the design, synthesis and evaluation of novel peptidomimetics compounds as HIV-1 protease inhibitors. Here is presented one-step, two-step and three-step syntheses and the in vitro bio-assay studies of a series of fully characterized peptidomimetics as HIV-1 protease inhibitors candidate using the shortest and most cost effective synthetic routes. The first series of compounds were accessed via a synthetic elaboration of Morita-Baylis-Hillman adducts by a Michael addition with benzylamine, proline or glycine esters to afford a series of β-amino-β’-hydroxycarboxylate esters in moderate to good yields. Base-catalyzed cyclization of non-benzylated aza-Michael adducts afforded a series of coumarin-3-hydroxy-2-methylenepropanoate esters in moderate yields. The uncatalyzed direct amidation of diethyl tartrate/tartaric acid and tartaric acid osazone with selected amines/amino acids afforded a series of C2-symmetrical and unsymmetrical 1,2-dihydroxycarboxylates in moderate to very high yields. All the synthesized compounds were fully characterized using spectroscopic techniques. These conjugates, designed as potential HIV-1 inhibitors, were tested against the HIV-1 protease enzyme. A number of these ligands have exhibited inhibition levels and IC50 values comparable to ritonavir, permitting, therefore, their identification as lead compounds for the development of novel inhibitors. , Thesis (PhD) -- Faculty of Science, Chemistry, 2020
- Full Text: false
- Date Issued: 2020
Men in Women’s Clothes
- Authors: Jones, Ward E
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/275658 , vital:55067 , xlink:href="https://doi.org/10.1111/sjp.12394"
- Description: The descriptive phrase that comprises my title can refer both to a pervasive comic trope and a mode of self-expression. There is a tension here, insofar as the comic trope leads us not to take cross-dressing, or drag, seriously. The first half of the comic film Some Like It Hot (1959), with its cross-gender plot and its (sophisticated but) straightforward use of the comic trope of men-in-women’s clothes, appears to fall foul of this tension and to be susceptible to criticism in this regard. However, the film rectifies itself, portraying the cross-dressing relationship which develops through the second half of the film as a potentially meaningful one for both partners. In this article, I interpret the film as inviting its viewers to adopt a (particular kind of) skeptical ironic (that is, Pyrrhonian) attitude toward gender-presentation practices. While the film in no way attempts to discourage us from participating in such practices, it does invite us—through our partiality toward the characters Osgood and Jerry/Daphne, as we follow their budding, transgressive relationship—to acknowledge that a violation of gender-presentation practices can be a meaningful feature of sincere relationships.
- Full Text:
- Date Issued: 2020
- Authors: Jones, Ward E
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/275658 , vital:55067 , xlink:href="https://doi.org/10.1111/sjp.12394"
- Description: The descriptive phrase that comprises my title can refer both to a pervasive comic trope and a mode of self-expression. There is a tension here, insofar as the comic trope leads us not to take cross-dressing, or drag, seriously. The first half of the comic film Some Like It Hot (1959), with its cross-gender plot and its (sophisticated but) straightforward use of the comic trope of men-in-women’s clothes, appears to fall foul of this tension and to be susceptible to criticism in this regard. However, the film rectifies itself, portraying the cross-dressing relationship which develops through the second half of the film as a potentially meaningful one for both partners. In this article, I interpret the film as inviting its viewers to adopt a (particular kind of) skeptical ironic (that is, Pyrrhonian) attitude toward gender-presentation practices. While the film in no way attempts to discourage us from participating in such practices, it does invite us—through our partiality toward the characters Osgood and Jerry/Daphne, as we follow their budding, transgressive relationship—to acknowledge that a violation of gender-presentation practices can be a meaningful feature of sincere relationships.
- Full Text:
- Date Issued: 2020
Development of phthalocyanine functionalised TiO 2 and ZnO nanofibers for photodegradation of methyl orange
- Mapukata, Sivuyisiwe, Nyokong, Tebello
- Authors: Mapukata, Sivuyisiwe , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186323 , vital:44485 , xlink:href="https://doi.org/10.1039/D0NJ03326J"
- Description: The photocatalytic activity of TiO2 and ZnO based catalysts, which is based on their ability to generate electron–hole pairs upon photoillumination is limited due to their wide band gaps and lack of efficient retrievability post-application. This work reports on the fabrication, characterisation and comparison of electrospun TiO2 and ZnO nanofibers when bare vs when functionalised with a phthalocyanine. The generated photocatalysts are attractive because they absorb visible light and are easily retrievable and hence reusable. With the Pc anchored onto their surfaces, the anatase TiO2 nanofibers and the wurzite ZnO nanofibers possessed singlet oxygen quantum yields of 0.22 and 0.16 in water, respectively. Evaluation of the photocatalytic efficiencies of the nanofibers was conducted by studying the photodegradation of methyl orange. The Pc decorated nanofibers were found to be more effective photocatalysts than the bare ones with the phthalocyanine TiO2 nanofibers being the best. The degradation kinetics were found to follow pseudo first order kinetics and obeyed the Langmuir Hinshelwood model. The nanocatalysts reported herein are therefore feasible candidates for real-life water purification applications.
- Full Text:
- Date Issued: 2020
- Authors: Mapukata, Sivuyisiwe , Nyokong, Tebello
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/186323 , vital:44485 , xlink:href="https://doi.org/10.1039/D0NJ03326J"
- Description: The photocatalytic activity of TiO2 and ZnO based catalysts, which is based on their ability to generate electron–hole pairs upon photoillumination is limited due to their wide band gaps and lack of efficient retrievability post-application. This work reports on the fabrication, characterisation and comparison of electrospun TiO2 and ZnO nanofibers when bare vs when functionalised with a phthalocyanine. The generated photocatalysts are attractive because they absorb visible light and are easily retrievable and hence reusable. With the Pc anchored onto their surfaces, the anatase TiO2 nanofibers and the wurzite ZnO nanofibers possessed singlet oxygen quantum yields of 0.22 and 0.16 in water, respectively. Evaluation of the photocatalytic efficiencies of the nanofibers was conducted by studying the photodegradation of methyl orange. The Pc decorated nanofibers were found to be more effective photocatalysts than the bare ones with the phthalocyanine TiO2 nanofibers being the best. The degradation kinetics were found to follow pseudo first order kinetics and obeyed the Langmuir Hinshelwood model. The nanocatalysts reported herein are therefore feasible candidates for real-life water purification applications.
- Full Text:
- Date Issued: 2020
A narrative study of students’ and staff’s experiences of living with HIV and AIDS at Rhodes University
- Authors: Tsope, Lindiwe
- Date: 2021-04
- Subjects: AIDS (Disease) South Africa Makhanda , HIV infections South Africa Makhanda , College students Health and hygiene South Africa Makhanda , Universities and colleges South Africa Makhanda Employees Health and hygiene , Stigma (Social psychology) , AIDS (Disease) Social aspects South Africa Makhanda , HIV infections Social aspects South Africa Makhanda , AIDS (Disease) Psychological aspects , HIV infections Psychological aspects , Health counseling South Africa Makhanda , Discourse analysis, Narrative
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/176894 , vital:42769 , 10.21504/10962/176894
- Description: A narrative study of students’ and staff’s experiences of living with HIV and AIDS at Rhodes University Research on HIV and AIDS in university settings, especially research exploring the experience of living with the disease, has been minimal. As a response to the knowledge and research gaps, this thesis is a qualitative study involving students and staff living with HIV (LWH) and accessing treatment (ART) at the Rhodes University Health Care Centre. This study explored the personal and social symbolisms as well as meanings attached to living with HIV, through in-depth interviews with ten students and staff living with HIV, all purposively sampled and recruited through the Rhodes University Health Care Centre. Using social constructionism, symbolic interactionism and the theory of biographical disruption, the narratives revealed a positive and inspirational side of living with HIV and AIDS – especially emphasizing that PLWHA do not have to surrender to the deadly narrative of the disease. It became evident that stigma, both internal and external, largely influences illness narratives. Furthermore, the study revealed the social reconstruction of life narratives both in order to understand the illness in terms of past social experiences and to reaffirm the impression that life has a course and the self has a purpose. All participants found that accessing treatment from the Rhodes University Health Care Centre positively influenced their experiences of adherence and reconstruction of narratives. The study indicates that HIV-related interventions in place at the university need to pay more attention to the psychosocial needs of PLWH, involvement of PWLH, as well as keeping up with the continuously changing global HIV narrative. The study argues for more attention to in-depth experiences and personal narratives in HIV and AIDS, and PLWHA education at Rhodes University. , Thesis (PhD) -- Humanities, Department of Sociology, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Tsope, Lindiwe
- Date: 2021-04
- Subjects: AIDS (Disease) South Africa Makhanda , HIV infections South Africa Makhanda , College students Health and hygiene South Africa Makhanda , Universities and colleges South Africa Makhanda Employees Health and hygiene , Stigma (Social psychology) , AIDS (Disease) Social aspects South Africa Makhanda , HIV infections Social aspects South Africa Makhanda , AIDS (Disease) Psychological aspects , HIV infections Psychological aspects , Health counseling South Africa Makhanda , Discourse analysis, Narrative
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/176894 , vital:42769 , 10.21504/10962/176894
- Description: A narrative study of students’ and staff’s experiences of living with HIV and AIDS at Rhodes University Research on HIV and AIDS in university settings, especially research exploring the experience of living with the disease, has been minimal. As a response to the knowledge and research gaps, this thesis is a qualitative study involving students and staff living with HIV (LWH) and accessing treatment (ART) at the Rhodes University Health Care Centre. This study explored the personal and social symbolisms as well as meanings attached to living with HIV, through in-depth interviews with ten students and staff living with HIV, all purposively sampled and recruited through the Rhodes University Health Care Centre. Using social constructionism, symbolic interactionism and the theory of biographical disruption, the narratives revealed a positive and inspirational side of living with HIV and AIDS – especially emphasizing that PLWHA do not have to surrender to the deadly narrative of the disease. It became evident that stigma, both internal and external, largely influences illness narratives. Furthermore, the study revealed the social reconstruction of life narratives both in order to understand the illness in terms of past social experiences and to reaffirm the impression that life has a course and the self has a purpose. All participants found that accessing treatment from the Rhodes University Health Care Centre positively influenced their experiences of adherence and reconstruction of narratives. The study indicates that HIV-related interventions in place at the university need to pay more attention to the psychosocial needs of PLWH, involvement of PWLH, as well as keeping up with the continuously changing global HIV narrative. The study argues for more attention to in-depth experiences and personal narratives in HIV and AIDS, and PLWHA education at Rhodes University. , Thesis (PhD) -- Humanities, Department of Sociology, 2021
- Full Text:
- Date Issued: 2021-04
Effects of organic and inorganic pollutants on the quality of river water and evaluation of possible negative effects on human health in the Eastern Cape Province
- Authors: Vumazonke, Sesethu
- Date: 2020-04
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MSc (Pharmacy)
- Identifier: http://hdl.handle.net/10962/164727 , vital:41158
- Description: Thesis (MSc)--Rhodes University, Faculty of Pharmacy, Pharmaceutics, 2020
- Full Text:
- Date Issued: 2020-04
- Authors: Vumazonke, Sesethu
- Date: 2020-04
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MSc (Pharmacy)
- Identifier: http://hdl.handle.net/10962/164727 , vital:41158
- Description: Thesis (MSc)--Rhodes University, Faculty of Pharmacy, Pharmaceutics, 2020
- Full Text:
- Date Issued: 2020-04
Climate responsive innovation within the agricultural curriculum and learning system
- Authors: van Staden, Wilma
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/389744 , vital:68479 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/186598"
- Description: The purpose of this paper is to outline the climate responsive innovation process within the agricultural innovation system of the North West Province, South Africa. The focus was on the embedded curriculum and learning activity system and its responses to social-ecological and earth system changes influenced by climate change. It outlines the barriers and processes hampering curriculum and learning innovations towards climate-smart responsiveness, and also examines the processes required to initiate micro and macro innovations. This paper focusses on how actors within the system can initiate curriculum innovation and climate responsiveness through micro innovations when supported and how this can lead to macro innovations. The system experienced various barriers during the innovation process and overcame many challenges during the journey towards climate-smart responsiveness through the identification of contradictions within the system, developing tools to assist in the transitioning process and expansion in the social-spatial dimension by establishing a learning network within the surrounding communities. The research indicated that the catalysing of the curriculum and learning system required specific tools, time and the understanding of the importance of micro-level innovation.
- Full Text:
- Date Issued: 2020
- Authors: van Staden, Wilma
- Date: 2020
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/389744 , vital:68479 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/186598"
- Description: The purpose of this paper is to outline the climate responsive innovation process within the agricultural innovation system of the North West Province, South Africa. The focus was on the embedded curriculum and learning activity system and its responses to social-ecological and earth system changes influenced by climate change. It outlines the barriers and processes hampering curriculum and learning innovations towards climate-smart responsiveness, and also examines the processes required to initiate micro and macro innovations. This paper focusses on how actors within the system can initiate curriculum innovation and climate responsiveness through micro innovations when supported and how this can lead to macro innovations. The system experienced various barriers during the innovation process and overcame many challenges during the journey towards climate-smart responsiveness through the identification of contradictions within the system, developing tools to assist in the transitioning process and expansion in the social-spatial dimension by establishing a learning network within the surrounding communities. The research indicated that the catalysing of the curriculum and learning system required specific tools, time and the understanding of the importance of micro-level innovation.
- Full Text:
- Date Issued: 2020
Volatility spillovers and determinants of contagion: a case of BRICS equity and foreign exchange markets
- Authors: Nyopa, Tšepiso
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MCOM
- Identifier: http://hdl.handle.net/10962/164590 , vital:41146
- Description: Thesis (MSc)--Rhodes University, Faculty of Commerce, Economics and Economic History, 2020
- Full Text:
- Date Issued: 2020
- Authors: Nyopa, Tšepiso
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MCOM
- Identifier: http://hdl.handle.net/10962/164590 , vital:41146
- Description: Thesis (MSc)--Rhodes University, Faculty of Commerce, Economics and Economic History, 2020
- Full Text:
- Date Issued: 2020
Orchid mycorrhizal and endophytic fungal diversity of three cooccurring terrestrial orchids in the large African genus Disa (Orchidaceae)
- Authors: Le Du, Bridgitte M
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MA
- Identifier: http://hdl.handle.net/10962/163363 , vital:41033
- Description: Thesis (MA)--Rhodes University, Faculty of Humanities, English Language and Linguistics, 2020.
- Full Text:
- Date Issued: 2020
- Authors: Le Du, Bridgitte M
- Date: 2020
- Subjects: Uncatalogued
- Language: English
- Type: thesis , text , Masters , MA
- Identifier: http://hdl.handle.net/10962/163363 , vital:41033
- Description: Thesis (MA)--Rhodes University, Faculty of Humanities, English Language and Linguistics, 2020.
- Full Text:
- Date Issued: 2020