Comparison of behaviour between traditional male circumcision initiates of the yesteryears and those of the contemporary epoch in Cala and Mdantsane, Eastern Cape
- Mpateni, Aphiwe https://orcid.org/0000-0002-6823-9179
- Authors: Mpateni, Aphiwe https://orcid.org/0000-0002-6823-9179
- Date: 2021-04
- Subjects: Circumcision , Xhosa (African people) -- Rites and ceremonies
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22045 , vital:51968
- Description: Unequivocally, the traditional male circumcision as rite of passage in South African communities has been embraced for its role in shaping the behaviour among the initiates. This rite was highly valuable during the yesteryears as the traditional male circumcision initiates portrayed compliance with the society’s moral codes and cultural goalposts. Inopportunely, on the other hand, during the contemporary epoch this rite of passage and the cultural underpinnings embedded in it appear to be eroding and shifting from the initial purpose of inculcating good behaviour and morals. This study seeks to compare the behaviour of the yesteryears’ traditional male circumcision initiates and those of the contemporary epoch in Cala, Sakhisizwe Local Municipality and Mdantsane, Buffalo City Municipality in Eastern Cape. This study aimed to achieve the following objectives: (i) to explore the policy differences informing TMC practices in yesteryears and in the contemporary epoch; (ii) to identify the similarities and differences between the behaviour of the contemporary initiates and those of yesteryears; and (iii) to establish the environmental factors motivating the change of the behaviour apparent among the contemporary initiates as well as those of the yesteryears. This study is underpinned by the socio- cultural perspective, anomie theory, and social learning theory. Methodologically, this study was qualitative in nature, where the data was collected through one-on-one in-depth interviews, focus group discussions, and Key informants interviews. An interview guide with open-ended questions was used to collect the data. A sample size of forty (40) participants was purposively selected for interviews. The data collection process was cross- sectional in design. Content analysis was employed to analyze the data and findings were presented thematically. The study established policy differences informing TMC during the yesteryears and the contemporary epoch, in that the yesteryears’ policy environment was culturally grounded; while the contemporary one’s is informed by the current national constitution and human rights perspectives. In relation to the policy issues, the study further established elements of illusionary interpretation of rights by the contemporary TMC initiates; poor implementation of policy guiding TMC practice. Further, the study revealed behavioural and morality differences between the yesteryears’ and the contemporary TMC initiates. For instance, the yesteryears’ TMC initiates were reported to be more responsible and well- mannered as compared to the contemporary ones. The shortfalls in expected behaviour and morality for the contemporary TMC initiates were attributed to modernization, and education in the contemporary initiation schools, which does not meet the societal expectations. On the environmental factors motivating the change of behaviour of the TMC initiates; Yesteryears’ TMC initiates complying with moral codes and cultural goalposts; Non-compliance to the moral codes and cultural goalposts by the contemporary TMC initiates; Culture of alcoholism during the contemporary epoch. Based on these findings, this study recommends that the government of South Africa should augment the existing TMC policies to ensure that traditional male circumcision as rite of passage achieves its socio-cultural objective of shaping behaviour and morals. The study further recommends training for traditional nurses “amakhankatha” and traditional surgeons “iingcibi”; and hosting cultural events for cultural resuscitation. The conclusions of this study state that the government must work hand in hand with cultural custodians to ensure that traditional male circumcision practice shapes good behaviour and morals of the initiates. This is because glaring gaps associated with the rite. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Mpateni, Aphiwe https://orcid.org/0000-0002-6823-9179
- Date: 2021-04
- Subjects: Circumcision , Xhosa (African people) -- Rites and ceremonies
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22045 , vital:51968
- Description: Unequivocally, the traditional male circumcision as rite of passage in South African communities has been embraced for its role in shaping the behaviour among the initiates. This rite was highly valuable during the yesteryears as the traditional male circumcision initiates portrayed compliance with the society’s moral codes and cultural goalposts. Inopportunely, on the other hand, during the contemporary epoch this rite of passage and the cultural underpinnings embedded in it appear to be eroding and shifting from the initial purpose of inculcating good behaviour and morals. This study seeks to compare the behaviour of the yesteryears’ traditional male circumcision initiates and those of the contemporary epoch in Cala, Sakhisizwe Local Municipality and Mdantsane, Buffalo City Municipality in Eastern Cape. This study aimed to achieve the following objectives: (i) to explore the policy differences informing TMC practices in yesteryears and in the contemporary epoch; (ii) to identify the similarities and differences between the behaviour of the contemporary initiates and those of yesteryears; and (iii) to establish the environmental factors motivating the change of the behaviour apparent among the contemporary initiates as well as those of the yesteryears. This study is underpinned by the socio- cultural perspective, anomie theory, and social learning theory. Methodologically, this study was qualitative in nature, where the data was collected through one-on-one in-depth interviews, focus group discussions, and Key informants interviews. An interview guide with open-ended questions was used to collect the data. A sample size of forty (40) participants was purposively selected for interviews. The data collection process was cross- sectional in design. Content analysis was employed to analyze the data and findings were presented thematically. The study established policy differences informing TMC during the yesteryears and the contemporary epoch, in that the yesteryears’ policy environment was culturally grounded; while the contemporary one’s is informed by the current national constitution and human rights perspectives. In relation to the policy issues, the study further established elements of illusionary interpretation of rights by the contemporary TMC initiates; poor implementation of policy guiding TMC practice. Further, the study revealed behavioural and morality differences between the yesteryears’ and the contemporary TMC initiates. For instance, the yesteryears’ TMC initiates were reported to be more responsible and well- mannered as compared to the contemporary ones. The shortfalls in expected behaviour and morality for the contemporary TMC initiates were attributed to modernization, and education in the contemporary initiation schools, which does not meet the societal expectations. On the environmental factors motivating the change of behaviour of the TMC initiates; Yesteryears’ TMC initiates complying with moral codes and cultural goalposts; Non-compliance to the moral codes and cultural goalposts by the contemporary TMC initiates; Culture of alcoholism during the contemporary epoch. Based on these findings, this study recommends that the government of South Africa should augment the existing TMC policies to ensure that traditional male circumcision as rite of passage achieves its socio-cultural objective of shaping behaviour and morals. The study further recommends training for traditional nurses “amakhankatha” and traditional surgeons “iingcibi”; and hosting cultural events for cultural resuscitation. The conclusions of this study state that the government must work hand in hand with cultural custodians to ensure that traditional male circumcision practice shapes good behaviour and morals of the initiates. This is because glaring gaps associated with the rite. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2021
- Full Text:
- Date Issued: 2021-04
Continuing teacher professional development in the Environment Sector: A case study of Fundisa for Change continuing teacher professional development programme
- Authors: Nkhahle, Lebona Jerome
- Date: 2021-10-29
- Subjects: Environmental education South Africa , Pedagogical content knowledge , Teachers In-service training South Africa , Curriculum-based assessment South Africa , Fundisa for Change , Practice Architectures
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/192724 , vital:45254 , 10.21504/10962/192724
- Description: The importance of teachers being engaged in professional development initiatives is widely acknowledged in the literature and in most cases these initiatives are largely focused on addressing teachers’ lack of subject content knowledge. The problem of teachers having inadequate environmental knowledge is common in South Africa due to the fact that much of the environmental content knowledge in the curriculum is new, and environmental education itself is a new field. This is an area of interest in South Africa as a third iteration of the post-apartheid curriculum, the Curriculum and Assessment Policy Statement (CAPS) has recently been introduced into schools and many subjects have environmental learning content. Inadequate subject content knowledge influences teachers’ abilities to choose appropriate teaching and assessment methods and this might negatively affect the process of teaching and learning. Knowledgeable teachers are needed to help learners understand the current issues affecting citizens, and in particular, environmental issues, which form the focus of this study. The main research questions addressed are: 1. What are the teachers’ experiences of the Fundisa for Change continuing teacher professional development programme in relation to environment and sustainability content knowledge? 2. How does the Fundisa for Change continuing teacher professional development programme influence teachers’ practice? 3. What practices of the Fundisa for Change teacher professional development programme are characteristic of effective continuing teacher professional development initiatives? 4. How are (if at all) the practices of teacher training, teacher learning, teaching and assessment of Biodiversity content in CAPS living practices? This work was conducted as a qualitative case study and it was carried out in the provinces of Gauteng, Eastern Cape and Mpumalanga in South Africa. It included four teachers from the Eastern Cape and five from Mpumalanga. Seven teacher trainers also participated, two of which were based in Gauteng and the rest in the Eastern Cape. Data were generated through interviews and document analysis, and included analysis of teacher portfolios showing evidence of classroom practice. The study explored teachers’ experiences of an environmental education training programme called ‘Fundisa for Change’, which has been set up as a national partnership initiative to strengthen teachers’ environmental knowledge and teaching skills in order to address the above-mentioned problem. It focused on training teachers in the Life Sciences, particularly on new content knowledge on Biodiversity, and on teaching and assessment skills. It also looked into how the training influenced teaching practice. The study worked with practice theory, in particular Kemmis and Grootenboer’s (2008) theory of practice architectures, to look at the sayings, doings and relatings pertaining to the teaching of Biodiversity, and the enabling and constraining of this practice. The features and the teachers’ experiences of the Fundisa for Change professional development programme have been presented and explained. The study also used the ecologies of practices theory to describe the living nature of practices. The following are the key findings: • The Fundisa for Change programme improved the participating teachers’ Biodiversity content knowledge, teaching and assessment skills. • Practices of the Fundisa for Change teacher professional development programme characteristic of effective continuing teacher professional development initiatives are: duration; active involvement of teachers; providing teachers with subject content knowledge; promoting establishment of professional learning communities; coherence; follow-up; and assessment of teachers. • The conditions that affect the participating teachers’ teaching practice are: the use of language (both scientific and instructional); infrastructure (availability of computer laboratories, science laboratories, extra classrooms and libraries); teaching and learning support materials including laboratory apparatus; class size; and policies. • The Fundisa for Change programme encourages teachers to improvise and use the local environment in their teaching to try to tackle the problem of lack of funds and equipment. • Teaching Biodiversity practice is ‘living’ as it is characterised by the principles of living ecologies. Recommendations based on the findings are: • There is a need for more teacher training by Fundisa for Change and other organisations whose training activities are SACE approved to cater for more teachers. • A more structured plan of action from the Department of Basic Education (DBE) is needed to assist and involve more organisations and stakeholders. • Provision of infrastructure and teaching and learning resource materials to schools by the DBE needs to be accelerated as it is legally binding. • Follow-up should be formally incorporated into Fundisa for Change programme activities. • Formation of professional learning communities is very important to help new teachers as there is no formal induction programme in South Africa. • An induction policy by the DBE needs to be formulated to help establish an induction programme for newly qualified teachers. Recommendations for further research are: • Use of lesson observation for data collection to improve results. • A larger sample could be used to expand the insights gained in this study. • Fundisa for Change practices can be studied at the level of teacher professional development practices. • Other modes of teacher professional development initiatives such as Lesson Study can be tested out to overcome the challenge of teachers not wanting to be observed. • More research can be carried out on the practices of teacher training, teacher learning, student learning and assessment, as practices associated with teaching Biodiversity. The study was important in that it gave an understanding of what makes continuing teacher professional development initiatives effective. The study also looked at teaching Biodiversity through the use of contemporary forms of a practice theory which are the theory of practice architectures and the theory of the ecologies of practices. This provided understandings into how professional development programmes are experienced in practice, and showed that though the teachers were trained and positive benefits accrued, there are factors which enable or constrain their actual teaching Biodiversity practice. The study also showed that practices are interrelated in ecologies of practices. These factors need to be considered in professional development programming. , Thesis (PhD) -- Faculty of Education, Education, 2021
- Full Text:
- Date Issued: 2021-10-29
- Authors: Nkhahle, Lebona Jerome
- Date: 2021-10-29
- Subjects: Environmental education South Africa , Pedagogical content knowledge , Teachers In-service training South Africa , Curriculum-based assessment South Africa , Fundisa for Change , Practice Architectures
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/192724 , vital:45254 , 10.21504/10962/192724
- Description: The importance of teachers being engaged in professional development initiatives is widely acknowledged in the literature and in most cases these initiatives are largely focused on addressing teachers’ lack of subject content knowledge. The problem of teachers having inadequate environmental knowledge is common in South Africa due to the fact that much of the environmental content knowledge in the curriculum is new, and environmental education itself is a new field. This is an area of interest in South Africa as a third iteration of the post-apartheid curriculum, the Curriculum and Assessment Policy Statement (CAPS) has recently been introduced into schools and many subjects have environmental learning content. Inadequate subject content knowledge influences teachers’ abilities to choose appropriate teaching and assessment methods and this might negatively affect the process of teaching and learning. Knowledgeable teachers are needed to help learners understand the current issues affecting citizens, and in particular, environmental issues, which form the focus of this study. The main research questions addressed are: 1. What are the teachers’ experiences of the Fundisa for Change continuing teacher professional development programme in relation to environment and sustainability content knowledge? 2. How does the Fundisa for Change continuing teacher professional development programme influence teachers’ practice? 3. What practices of the Fundisa for Change teacher professional development programme are characteristic of effective continuing teacher professional development initiatives? 4. How are (if at all) the practices of teacher training, teacher learning, teaching and assessment of Biodiversity content in CAPS living practices? This work was conducted as a qualitative case study and it was carried out in the provinces of Gauteng, Eastern Cape and Mpumalanga in South Africa. It included four teachers from the Eastern Cape and five from Mpumalanga. Seven teacher trainers also participated, two of which were based in Gauteng and the rest in the Eastern Cape. Data were generated through interviews and document analysis, and included analysis of teacher portfolios showing evidence of classroom practice. The study explored teachers’ experiences of an environmental education training programme called ‘Fundisa for Change’, which has been set up as a national partnership initiative to strengthen teachers’ environmental knowledge and teaching skills in order to address the above-mentioned problem. It focused on training teachers in the Life Sciences, particularly on new content knowledge on Biodiversity, and on teaching and assessment skills. It also looked into how the training influenced teaching practice. The study worked with practice theory, in particular Kemmis and Grootenboer’s (2008) theory of practice architectures, to look at the sayings, doings and relatings pertaining to the teaching of Biodiversity, and the enabling and constraining of this practice. The features and the teachers’ experiences of the Fundisa for Change professional development programme have been presented and explained. The study also used the ecologies of practices theory to describe the living nature of practices. The following are the key findings: • The Fundisa for Change programme improved the participating teachers’ Biodiversity content knowledge, teaching and assessment skills. • Practices of the Fundisa for Change teacher professional development programme characteristic of effective continuing teacher professional development initiatives are: duration; active involvement of teachers; providing teachers with subject content knowledge; promoting establishment of professional learning communities; coherence; follow-up; and assessment of teachers. • The conditions that affect the participating teachers’ teaching practice are: the use of language (both scientific and instructional); infrastructure (availability of computer laboratories, science laboratories, extra classrooms and libraries); teaching and learning support materials including laboratory apparatus; class size; and policies. • The Fundisa for Change programme encourages teachers to improvise and use the local environment in their teaching to try to tackle the problem of lack of funds and equipment. • Teaching Biodiversity practice is ‘living’ as it is characterised by the principles of living ecologies. Recommendations based on the findings are: • There is a need for more teacher training by Fundisa for Change and other organisations whose training activities are SACE approved to cater for more teachers. • A more structured plan of action from the Department of Basic Education (DBE) is needed to assist and involve more organisations and stakeholders. • Provision of infrastructure and teaching and learning resource materials to schools by the DBE needs to be accelerated as it is legally binding. • Follow-up should be formally incorporated into Fundisa for Change programme activities. • Formation of professional learning communities is very important to help new teachers as there is no formal induction programme in South Africa. • An induction policy by the DBE needs to be formulated to help establish an induction programme for newly qualified teachers. Recommendations for further research are: • Use of lesson observation for data collection to improve results. • A larger sample could be used to expand the insights gained in this study. • Fundisa for Change practices can be studied at the level of teacher professional development practices. • Other modes of teacher professional development initiatives such as Lesson Study can be tested out to overcome the challenge of teachers not wanting to be observed. • More research can be carried out on the practices of teacher training, teacher learning, student learning and assessment, as practices associated with teaching Biodiversity. The study was important in that it gave an understanding of what makes continuing teacher professional development initiatives effective. The study also looked at teaching Biodiversity through the use of contemporary forms of a practice theory which are the theory of practice architectures and the theory of the ecologies of practices. This provided understandings into how professional development programmes are experienced in practice, and showed that though the teachers were trained and positive benefits accrued, there are factors which enable or constrain their actual teaching Biodiversity practice. The study also showed that practices are interrelated in ecologies of practices. These factors need to be considered in professional development programming. , Thesis (PhD) -- Faculty of Education, Education, 2021
- Full Text:
- Date Issued: 2021-10-29
A problematisation of Afrikaner identity subject positions as found in the coverage of contemporary Afrikaans music in HUISGENOOT magazine discourse
- Authors: Hughes, Lestie
- Date: 2021-04
- Subjects: Afrikaners -- South Africa -- Music -- History and criticism , Multimedia (Art)
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/52558 , vital:43686
- Description: Through the lens of Foucauldian genealogy, this thesis problematises the subject positions towards Afrikaner identity reflected in contemporary Afrikaans songs covered by Huisgenoot magazine. Such a genealogical exploration thematises the games of truth underpinning the formation of Huisgenoot, highlights its role in solidifying white Afrikaner Nationalist discourse of apartheid, observes its more populist, profit-oriented approach from the 1970s onwards and considers the residual echoing of its former discursive orientation. The song analysis of selected Afrikaans songs/music videos covered in Huisgenoot is guided by the semiotics of Nicholas Cook, such that it frames the analytical question of how such music is driven by conformance, contest and complementation between multi-media elements in ways that make meaning possible. Accordingly, this methodology resonates with the non-essentialising focus of Foucauldian problematisation, premised on critical resistance that makes new responses simultaneously possible. The self-reflexive autoethnographical approach employed, entailing the author’s dialogical engagement with her own ‘Afrikaner self’, similarly facilitates the dynamic interplay between multiplicities. Correlatively, on the one hand, more ‘closed’ and more ‘open’ Afrikaner identity positions reflected within the songs are analysed, as well as seemingly ‘reconciliatory’ / collaborative’ musical manifestations which ultimately revert back to more ‘closed’ identity constructs. But on the other hand, observation of adherence to a ‘white-black’ dichotomy within songs that manifest more ‘closed’ identity positions also leads to consideration of the parallels between the goals of white Afrikaner Nationalism and the current Decolonisation narrative, which is informed by Black Consciousness thought and generated by the ‘Colonisation of a Special Kind’ ANC policy. Both such Decolonisation rhetoric and the countering rhetoric of the Neo-Afrikaner Protest Movement (NAP) are thus identified as metanarratives, underpinned by a ‘white-black’ dichotomy. In this regard, while Huisgenoot’s predisposition towards songs manifesting more ‘closed’ Afrikaner identity positions is considered in terms of its aforementioned profit-oriented endeavour to appeal to its ostensible primary readership, an encouraging increase in coverage of coloured artists is both noted and occasionally seen to overlap with its coverage of songs manifesting more ‘open’ Afrikaner identity positions. Among the latter one may – again in Foucauldian terms – differentiate between songs focussed on an engagement in cross-cultural relations of power, and songs intent on shattering states of domination of power blocks, often through shocking juxtaposition of disparate elements. These more violently dismantling endeavours, it is argued, comprise examples of Foucauldian transversal struggles, although their coverage in Huisgenoot is also attributed to their shock value and/or record sales, rather than their transformational potential. Furthermore, such Huisgenoot coverage is also seen to place more transformationally oriented artists at risk of media ‘domestication’, with its concomitant inhibiting of creativity. Finally, the researcher’s commitment to creative problematisation of her own Afrikaner identity, coupled with acknowledgement of her inescapable textual entrapment, culminates in her acceptance of the continual flux characterising dialogical power relations, before she – in accordance with the Foucauldian methodology employed – presents all ‘conclusions’ in a non-dictatorial spirit of ‘truth creation’, desirous of continual self/other dialogue. , Thesis (PhD) -- Faculty of Humanities, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Hughes, Lestie
- Date: 2021-04
- Subjects: Afrikaners -- South Africa -- Music -- History and criticism , Multimedia (Art)
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/52558 , vital:43686
- Description: Through the lens of Foucauldian genealogy, this thesis problematises the subject positions towards Afrikaner identity reflected in contemporary Afrikaans songs covered by Huisgenoot magazine. Such a genealogical exploration thematises the games of truth underpinning the formation of Huisgenoot, highlights its role in solidifying white Afrikaner Nationalist discourse of apartheid, observes its more populist, profit-oriented approach from the 1970s onwards and considers the residual echoing of its former discursive orientation. The song analysis of selected Afrikaans songs/music videos covered in Huisgenoot is guided by the semiotics of Nicholas Cook, such that it frames the analytical question of how such music is driven by conformance, contest and complementation between multi-media elements in ways that make meaning possible. Accordingly, this methodology resonates with the non-essentialising focus of Foucauldian problematisation, premised on critical resistance that makes new responses simultaneously possible. The self-reflexive autoethnographical approach employed, entailing the author’s dialogical engagement with her own ‘Afrikaner self’, similarly facilitates the dynamic interplay between multiplicities. Correlatively, on the one hand, more ‘closed’ and more ‘open’ Afrikaner identity positions reflected within the songs are analysed, as well as seemingly ‘reconciliatory’ / collaborative’ musical manifestations which ultimately revert back to more ‘closed’ identity constructs. But on the other hand, observation of adherence to a ‘white-black’ dichotomy within songs that manifest more ‘closed’ identity positions also leads to consideration of the parallels between the goals of white Afrikaner Nationalism and the current Decolonisation narrative, which is informed by Black Consciousness thought and generated by the ‘Colonisation of a Special Kind’ ANC policy. Both such Decolonisation rhetoric and the countering rhetoric of the Neo-Afrikaner Protest Movement (NAP) are thus identified as metanarratives, underpinned by a ‘white-black’ dichotomy. In this regard, while Huisgenoot’s predisposition towards songs manifesting more ‘closed’ Afrikaner identity positions is considered in terms of its aforementioned profit-oriented endeavour to appeal to its ostensible primary readership, an encouraging increase in coverage of coloured artists is both noted and occasionally seen to overlap with its coverage of songs manifesting more ‘open’ Afrikaner identity positions. Among the latter one may – again in Foucauldian terms – differentiate between songs focussed on an engagement in cross-cultural relations of power, and songs intent on shattering states of domination of power blocks, often through shocking juxtaposition of disparate elements. These more violently dismantling endeavours, it is argued, comprise examples of Foucauldian transversal struggles, although their coverage in Huisgenoot is also attributed to their shock value and/or record sales, rather than their transformational potential. Furthermore, such Huisgenoot coverage is also seen to place more transformationally oriented artists at risk of media ‘domestication’, with its concomitant inhibiting of creativity. Finally, the researcher’s commitment to creative problematisation of her own Afrikaner identity, coupled with acknowledgement of her inescapable textual entrapment, culminates in her acceptance of the continual flux characterising dialogical power relations, before she – in accordance with the Foucauldian methodology employed – presents all ‘conclusions’ in a non-dictatorial spirit of ‘truth creation’, desirous of continual self/other dialogue. , Thesis (PhD) -- Faculty of Humanities, 2021
- Full Text:
- Date Issued: 2021-04
Applying a systems analysis approach to support marine spatial planning in Algoa Bay, South Africa
- Authors: Vermeulen, Estee Ann
- Date: 2021-12
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/54121 , vital:46312
- Description: Ocean health provides the foundation for human health through the provisioning of ecosystem services. Increasing demands on ocean space and resources are, however, resulting in a decline in ocean health, with direct and indirect knock-on effects on marine uses and ultimately on human health. In response, there is a growing need to acknowledge and better manage complex human-ocean interactions. This has been recognised in global sustainable development goals and in integrated ocean management processes, leading to widespread endorsement of an ecosystem-based marine spatial planning (MSP) process, including in South Africa. In support of the national MSP process, significant progress has been made in understanding the spatial extent of marine activities and associated marine pressures, but the temporal dynamics of marine activities and interconnections with the marine environment are less well understood. To plan for the growth of marine activities and associated user conflicts, the drivers of these temporal dynamics and associated feedback effects need to be analysed and potential policy and management interventions identified and tested. To support South Africa’s national MSP process, this study adopts a systems analysis approach, using system dynamics modelling, to explore the temporal change in marine uses under alternative growth scenarios in Algoa Bay. Algoa Bay is an appropriate study area because it is experiencing a rapid expansion of marine activities, coupled with a growing uncertainty regarding marine sustainability outcomes. To assist future marine management decisions, the Algoa Marine Systems Analysis Tool (Algoa MSAT) was developed, comprising seven sub-models. Five of the sub-models represent selected marine uses in Algoa Bay, whereas the sixth and seventh integrate the outputs from each marine use in terms of sustainable management indicators (marine health, marine wealth and marine labour). Model development primarily adopted an expert-based model ling approach, although the involvement of stakeholders, through a collaborative modelling process, assisted in integrating knowledge on different marine sectors’ activities, impacts and planning visions into the model framework. Model results were generated under different scenarios to investigate changes in the growth of marine activities and marine sustainability indicators under different levels of ocean governance. Under the baseline (or business-as-usual) model scenario, marine activities were shown to grow increasingly within their respective management limits, with an increase in marine wealth and labour and a consequential decrease in marine health. This scenario particularly highlights that current ocean governance practices are ineffective in sustaining the projected growth of the marine uses, particularly for those that are vulnerable to negative changes in marine health. Conversely, sectors that hold more value in marine wealth and are more resilient to changes in marine health, may continue to grow regardless of negative knock-on effects of the health of the marine environment and on other uses in the bay. This emphasises that an alternative governance strategy is needed to achieve the long-term goal of an ecosystem-based MSP process, as required by South African MSP legislation. To achieve this will require multiple, adaptive cross-sectoral management interventions that are directed towards the ‘deeper leverage points’ that are able to maintain the growth of marine activities within appropriate limits defined by marine health. Using the model interface developed in this project, decision-makers and stakeholders can use the model to explore the temporal dynamics in marine activities under different governance scenarios. Although the model is limited to Algoa Bay, the model boundary can be adapted to assist in marine planning processes at national or trans-national scales. Such analytical assessments and tools are critical to progress the ecosystem-based management approach in MSP, as is required to achieve global sustainable development goals. , Thesis (PhD) -- Faculty of Science, Coastal and Marine Research Unit, 2021
- Full Text:
- Date Issued: 2021-12
- Authors: Vermeulen, Estee Ann
- Date: 2021-12
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/54121 , vital:46312
- Description: Ocean health provides the foundation for human health through the provisioning of ecosystem services. Increasing demands on ocean space and resources are, however, resulting in a decline in ocean health, with direct and indirect knock-on effects on marine uses and ultimately on human health. In response, there is a growing need to acknowledge and better manage complex human-ocean interactions. This has been recognised in global sustainable development goals and in integrated ocean management processes, leading to widespread endorsement of an ecosystem-based marine spatial planning (MSP) process, including in South Africa. In support of the national MSP process, significant progress has been made in understanding the spatial extent of marine activities and associated marine pressures, but the temporal dynamics of marine activities and interconnections with the marine environment are less well understood. To plan for the growth of marine activities and associated user conflicts, the drivers of these temporal dynamics and associated feedback effects need to be analysed and potential policy and management interventions identified and tested. To support South Africa’s national MSP process, this study adopts a systems analysis approach, using system dynamics modelling, to explore the temporal change in marine uses under alternative growth scenarios in Algoa Bay. Algoa Bay is an appropriate study area because it is experiencing a rapid expansion of marine activities, coupled with a growing uncertainty regarding marine sustainability outcomes. To assist future marine management decisions, the Algoa Marine Systems Analysis Tool (Algoa MSAT) was developed, comprising seven sub-models. Five of the sub-models represent selected marine uses in Algoa Bay, whereas the sixth and seventh integrate the outputs from each marine use in terms of sustainable management indicators (marine health, marine wealth and marine labour). Model development primarily adopted an expert-based model ling approach, although the involvement of stakeholders, through a collaborative modelling process, assisted in integrating knowledge on different marine sectors’ activities, impacts and planning visions into the model framework. Model results were generated under different scenarios to investigate changes in the growth of marine activities and marine sustainability indicators under different levels of ocean governance. Under the baseline (or business-as-usual) model scenario, marine activities were shown to grow increasingly within their respective management limits, with an increase in marine wealth and labour and a consequential decrease in marine health. This scenario particularly highlights that current ocean governance practices are ineffective in sustaining the projected growth of the marine uses, particularly for those that are vulnerable to negative changes in marine health. Conversely, sectors that hold more value in marine wealth and are more resilient to changes in marine health, may continue to grow regardless of negative knock-on effects of the health of the marine environment and on other uses in the bay. This emphasises that an alternative governance strategy is needed to achieve the long-term goal of an ecosystem-based MSP process, as required by South African MSP legislation. To achieve this will require multiple, adaptive cross-sectoral management interventions that are directed towards the ‘deeper leverage points’ that are able to maintain the growth of marine activities within appropriate limits defined by marine health. Using the model interface developed in this project, decision-makers and stakeholders can use the model to explore the temporal dynamics in marine activities under different governance scenarios. Although the model is limited to Algoa Bay, the model boundary can be adapted to assist in marine planning processes at national or trans-national scales. Such analytical assessments and tools are critical to progress the ecosystem-based management approach in MSP, as is required to achieve global sustainable development goals. , Thesis (PhD) -- Faculty of Science, Coastal and Marine Research Unit, 2021
- Full Text:
- Date Issued: 2021-12
The role of indigenous knowledge in agriculture and environmental conservation: the case of Gutu District Zimbabwe
- Authors: Wutete, Obert
- Date: 2014-01
- Subjects: Traditional ecological knowledge , Conservation of natural resources , Nature conservation
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26526 , vital:65520
- Description: Indigenous Knowledge IK is an emerging area of study that focuses on a community’s ways of knowing, seeing and thinking, developed over a long period of time. The knowledge is passed down orally from one generation to the other. Therefore, this study highlights a number of important factors that are associated with the use of IK in rural communities such as Gutu district. The major importance of IK include the following: it reduces costs through the use of locally available resources, acts as the basis of local-level decision making, is familiar and acceptable to the communities in which the knowledge exists and also that IK helps communities to develop their own sources of livelihoods. The objectives of the study were; to identify the types of IK peculiar to agriculture practices and the conservation of the environment within Gutu district; establish the challenges confronting IK utilization in communities; identify the constraints affecting the sharing, transfer and preservation of IK; determine the measures which should be adopted in order to promote the appreciation and value placed on IK in agriculture practices and the conservation of the environment; and to propose recommendations on how IK should be utilized for sustainable livelihoods in agriculture and environmental conservation in Gutu district and other rural communities. The study employed the survey method which was premised on the use of multiple data gathering tools, also referred to as triangulation. A total of 100 interviewees were sampled from Gutu communities for face-to-face interviews, 48 participants for focus group discussions, with each group comprising of 6 participants. The researcher collected data using a set of interview guide questions for individual participants as well as for the focus group discussions. In order to be comprehensive in data collection, the researcher also utilized observations and transects walks (these are random walks done in an area under study in order to have a better understanding of activities of the area). The triangulation of data gathering tools assisted with diverse information on the crops cultivated by residents, cultivation methods, harvesting and the preservation of the crops. The researcher also gathered information on how residents interacted with the environment, established reasons which contributed to the deterioration of the environment, established the sacredness associated with certain areas in Gutu district and the use of taboos as a way to safeguarding natural resources. The traditional practices have become a thing of the past to the present generations. The research had four major findings: First, it was found out that Indigenous Knowledge which was the basis of traditional lifestyles is no longer a major practice by Gutu residents. The gradual decline of traditional indigenous practices contributed among other factors to the decline in agriculture output. Residents have abandoned traditional farming methods such as conservation farming. The latter practice kept the soil intact and rich in fertility unlike the use of ploughs and tractors which weakens the soil. More so, residents have opted for the cultivation of crops which do not give them good harvests. Maize is one such crop which suffers from droughts as opposed to small grain crops, comprising of finger millet, pearl millet and sorghum. These endure dry conditions with limited rainfall. Gutu residents also revealed that there is overlooking of the sacredness associated with certain areas and the use of taboos to conserve the environment. It was further established that while residents have knowledge of sacred places and prohibitive taboos which are meant to safeguard the environment, residents no longer respect the prohibitions due to the influence of modernity and Christianity which regard some of the practices as backward or wayward beliefs. Second, the study established that the influence of colonial policies influenced a number of changes to the continued utilization of Indigenous Knowledge in agriculture and the management of the environment. For example, Gutu residents no longer practice shifting cultivation which used to be practice in the 1920s backwards. Residents are now confined to small pieces of land which are continuously cultivated on a yearly basis. Therefore, soils have become exhausted and production has gone down since the majority of residents are not able to replenish the soil through the use of fertilizer whose cost they cannot afford. It was also established that the environment has deteriorated continuously due to over use by an ever-increasing population. Third, the study found out that traditional platforms such as the dare men’s meeting place are no longer in existence. The dare is a set-up in which males sit around a fire place and shared ideas on different subject areas as a way of teaching one another life lessons and grooming the future generations. On the other hand, women use the round hut in which food is prepared to address a number of teachings to the girl child. Elderly women took the opportunity to induct young girls into adulthood along the duties expected of women in the society. Nowadays, both males and females share the hut used for preparing food and this is disrupting the traditional set-up of inducting young males and females in separate and appropriate platforms. The situation was worsened by colonialism which came along with Christian teachings, part of which were not in tandem with traditional indigenous practices. For example, the sacredness of places and the use of taboos are regarded by the youths as old and outdated beliefs with no relevance in today’s modern world. To make matter worse, there is limited contact time between the youths and the elders due to work commitments in urban areas. This has limited the opportunities for the sharing, transfer and preservation of IK as opposed to the traditional times in which shared communal lives allowed constant interactions and appreciation of indigenous ways of life. Fourth, there are no tangible strategies for the preservation of IK for posterity. While general information on traditional IK can be shared by residents, there are individuals who possess rare knowledge but made it their preserve after they realized that the knowledge offered them competitive advantages and benefits. Another aspect is that the youths have lost interest in IK of the past since they feel that the knowledge has lost relevance to their present interests due to the dynamism of culture. In the youths’ views, IK which is useful and relevant to their generation will continue to exist while practices which are no longer useful will fall by the way side. The research utilized interviews in order to establish the manner in which Indigenous Knowledge is acquired, shared, transferred and even retained for use by future generations. The findings of the study formed the basis for recommendations, of which if adopted, could contribute significantly to the revival of indigenous knowledge practices in Gutu district. The use of indigenous knowledge, peculiar to people in a given locality, can contribute to the promotion of sustainable livelihoods and development of rural communities in Gutu district. Based on the findings of the study, the following recommendations can be considered there is need for the establishment of Indigenous Knowledge Resource Centres IKRCs in communities so that individuals with interest in traditional IK can acquire the knowledge free of charge. It may also be beneficial if IK can be introduced to become part of the tertiary level curricula. Since Zimbabwe is an agro-based economy and also the fact that rural communities rely on the environment for provisions such as firewood, production and conservation measures being part of the curricula. This will assist decision makers to appreciate and value IK in decision making and development projects, not only in agriculture and the conservation of the environment, but also in other sectors that promote people’s livelihood. , Thesis (MA) -- Faculty of Social Sciences and Humanities, 2014
- Full Text:
- Date Issued: 2014-01
- Authors: Wutete, Obert
- Date: 2014-01
- Subjects: Traditional ecological knowledge , Conservation of natural resources , Nature conservation
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26526 , vital:65520
- Description: Indigenous Knowledge IK is an emerging area of study that focuses on a community’s ways of knowing, seeing and thinking, developed over a long period of time. The knowledge is passed down orally from one generation to the other. Therefore, this study highlights a number of important factors that are associated with the use of IK in rural communities such as Gutu district. The major importance of IK include the following: it reduces costs through the use of locally available resources, acts as the basis of local-level decision making, is familiar and acceptable to the communities in which the knowledge exists and also that IK helps communities to develop their own sources of livelihoods. The objectives of the study were; to identify the types of IK peculiar to agriculture practices and the conservation of the environment within Gutu district; establish the challenges confronting IK utilization in communities; identify the constraints affecting the sharing, transfer and preservation of IK; determine the measures which should be adopted in order to promote the appreciation and value placed on IK in agriculture practices and the conservation of the environment; and to propose recommendations on how IK should be utilized for sustainable livelihoods in agriculture and environmental conservation in Gutu district and other rural communities. The study employed the survey method which was premised on the use of multiple data gathering tools, also referred to as triangulation. A total of 100 interviewees were sampled from Gutu communities for face-to-face interviews, 48 participants for focus group discussions, with each group comprising of 6 participants. The researcher collected data using a set of interview guide questions for individual participants as well as for the focus group discussions. In order to be comprehensive in data collection, the researcher also utilized observations and transects walks (these are random walks done in an area under study in order to have a better understanding of activities of the area). The triangulation of data gathering tools assisted with diverse information on the crops cultivated by residents, cultivation methods, harvesting and the preservation of the crops. The researcher also gathered information on how residents interacted with the environment, established reasons which contributed to the deterioration of the environment, established the sacredness associated with certain areas in Gutu district and the use of taboos as a way to safeguarding natural resources. The traditional practices have become a thing of the past to the present generations. The research had four major findings: First, it was found out that Indigenous Knowledge which was the basis of traditional lifestyles is no longer a major practice by Gutu residents. The gradual decline of traditional indigenous practices contributed among other factors to the decline in agriculture output. Residents have abandoned traditional farming methods such as conservation farming. The latter practice kept the soil intact and rich in fertility unlike the use of ploughs and tractors which weakens the soil. More so, residents have opted for the cultivation of crops which do not give them good harvests. Maize is one such crop which suffers from droughts as opposed to small grain crops, comprising of finger millet, pearl millet and sorghum. These endure dry conditions with limited rainfall. Gutu residents also revealed that there is overlooking of the sacredness associated with certain areas and the use of taboos to conserve the environment. It was further established that while residents have knowledge of sacred places and prohibitive taboos which are meant to safeguard the environment, residents no longer respect the prohibitions due to the influence of modernity and Christianity which regard some of the practices as backward or wayward beliefs. Second, the study established that the influence of colonial policies influenced a number of changes to the continued utilization of Indigenous Knowledge in agriculture and the management of the environment. For example, Gutu residents no longer practice shifting cultivation which used to be practice in the 1920s backwards. Residents are now confined to small pieces of land which are continuously cultivated on a yearly basis. Therefore, soils have become exhausted and production has gone down since the majority of residents are not able to replenish the soil through the use of fertilizer whose cost they cannot afford. It was also established that the environment has deteriorated continuously due to over use by an ever-increasing population. Third, the study found out that traditional platforms such as the dare men’s meeting place are no longer in existence. The dare is a set-up in which males sit around a fire place and shared ideas on different subject areas as a way of teaching one another life lessons and grooming the future generations. On the other hand, women use the round hut in which food is prepared to address a number of teachings to the girl child. Elderly women took the opportunity to induct young girls into adulthood along the duties expected of women in the society. Nowadays, both males and females share the hut used for preparing food and this is disrupting the traditional set-up of inducting young males and females in separate and appropriate platforms. The situation was worsened by colonialism which came along with Christian teachings, part of which were not in tandem with traditional indigenous practices. For example, the sacredness of places and the use of taboos are regarded by the youths as old and outdated beliefs with no relevance in today’s modern world. To make matter worse, there is limited contact time between the youths and the elders due to work commitments in urban areas. This has limited the opportunities for the sharing, transfer and preservation of IK as opposed to the traditional times in which shared communal lives allowed constant interactions and appreciation of indigenous ways of life. Fourth, there are no tangible strategies for the preservation of IK for posterity. While general information on traditional IK can be shared by residents, there are individuals who possess rare knowledge but made it their preserve after they realized that the knowledge offered them competitive advantages and benefits. Another aspect is that the youths have lost interest in IK of the past since they feel that the knowledge has lost relevance to their present interests due to the dynamism of culture. In the youths’ views, IK which is useful and relevant to their generation will continue to exist while practices which are no longer useful will fall by the way side. The research utilized interviews in order to establish the manner in which Indigenous Knowledge is acquired, shared, transferred and even retained for use by future generations. The findings of the study formed the basis for recommendations, of which if adopted, could contribute significantly to the revival of indigenous knowledge practices in Gutu district. The use of indigenous knowledge, peculiar to people in a given locality, can contribute to the promotion of sustainable livelihoods and development of rural communities in Gutu district. Based on the findings of the study, the following recommendations can be considered there is need for the establishment of Indigenous Knowledge Resource Centres IKRCs in communities so that individuals with interest in traditional IK can acquire the knowledge free of charge. It may also be beneficial if IK can be introduced to become part of the tertiary level curricula. Since Zimbabwe is an agro-based economy and also the fact that rural communities rely on the environment for provisions such as firewood, production and conservation measures being part of the curricula. This will assist decision makers to appreciate and value IK in decision making and development projects, not only in agriculture and the conservation of the environment, but also in other sectors that promote people’s livelihood. , Thesis (MA) -- Faculty of Social Sciences and Humanities, 2014
- Full Text:
- Date Issued: 2014-01
Outcomes-based participatory gender planning and budgeting in South African local government context: a case of selected municipalities in the Eastern Cape Province
- Authors: Sikhosana, Nqobile
- Date: 2022-07
- Subjects: Municipal budgets
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23381 , vital:57620
- Description: This research is focused on the premise that engaging women and men in municipal budget preparation can be a precondition for achieving gender-sensitive service delivery outcomes. It follows, logically, that empowering citizens and granting them authority to control budget allocations has the potential to play a mediating role in transforming the financial management environment within the framework of local government in South Africa. Without representation of heterogeneous social classes, budget allocations in South Africa will continue to reflect the needs of those who hold the top echelons of municipal administrative machinery. Given the complexity of the flawed participatory structures and persistent gender inequality, the mixed methods approach was used as an investigative method to gain a deeper understanding of the participatory genderresponsive budgeting trend and its subsequent impact on service delivery outcomes in the Eastern Cape Province. The findings showed that men's participation and resource re-allocation elements had a significant effect on gender-responsive budgeting but women's participation and transparency had no significant impact. More so, findings also revealed that there is no difference in the manner in which the two municipalities have adopted the two concepts. The long-term results of male domination and the ignorance of transparency and women participation in budget formulation is the establishment of gender-blind budgets that fail to deliver gender-sensitive service delivery outcomes. Based on secondary data analysis, evidence showed that there is a lack of gender dimension in the municipal outcomes and this has contributed towards gender inequalities in terms of access to services. However, results indicated that the full involvement of women and giving then authority to have a voice in budgetary decisions, coupled with the transparent incorporation of gender priorities in the stages of the budget cycle can lead to the formulation to gender sensitive budgets. This knowledge allows the adoption of a participatory gender responsive model for local government. , Thesis (PhD) -- Faculty of Management and Commerce, 2022
- Full Text:
- Date Issued: 2022-07
- Authors: Sikhosana, Nqobile
- Date: 2022-07
- Subjects: Municipal budgets
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23381 , vital:57620
- Description: This research is focused on the premise that engaging women and men in municipal budget preparation can be a precondition for achieving gender-sensitive service delivery outcomes. It follows, logically, that empowering citizens and granting them authority to control budget allocations has the potential to play a mediating role in transforming the financial management environment within the framework of local government in South Africa. Without representation of heterogeneous social classes, budget allocations in South Africa will continue to reflect the needs of those who hold the top echelons of municipal administrative machinery. Given the complexity of the flawed participatory structures and persistent gender inequality, the mixed methods approach was used as an investigative method to gain a deeper understanding of the participatory genderresponsive budgeting trend and its subsequent impact on service delivery outcomes in the Eastern Cape Province. The findings showed that men's participation and resource re-allocation elements had a significant effect on gender-responsive budgeting but women's participation and transparency had no significant impact. More so, findings also revealed that there is no difference in the manner in which the two municipalities have adopted the two concepts. The long-term results of male domination and the ignorance of transparency and women participation in budget formulation is the establishment of gender-blind budgets that fail to deliver gender-sensitive service delivery outcomes. Based on secondary data analysis, evidence showed that there is a lack of gender dimension in the municipal outcomes and this has contributed towards gender inequalities in terms of access to services. However, results indicated that the full involvement of women and giving then authority to have a voice in budgetary decisions, coupled with the transparent incorporation of gender priorities in the stages of the budget cycle can lead to the formulation to gender sensitive budgets. This knowledge allows the adoption of a participatory gender responsive model for local government. , Thesis (PhD) -- Faculty of Management and Commerce, 2022
- Full Text:
- Date Issued: 2022-07
Comparative performance of 3-kWp ranges Solar Photovoltaic Systems under varying meteorological conditions in Alice, Eastern Cape Province, South Africa
- Apeh, Oliver Okechukwu https://orcid.org/0000-0003-4076-0613
- Authors: Apeh, Oliver Okechukwu https://orcid.org/0000-0003-4076-0613
- Date: 2021-08
- Subjects: Photovoltaic power systems , Solar energy
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/21567 , vital:48888
- Description: PVsystem has recently emerged in South Africa as a way to curb the country’s persistent shortage of electricity. A wide effort for the past few decades have targeted at study, testing and demonstration of PV power systems which was established all over the country as an appropriate measure to tackle transportation, agriculture, industry, commercial as well as domestic activities. In view of these drives, both off-grid and grid-connected PV systems are being applied. However, operating a building with an off-grid system is one of the means to providing the possibility of energy access to places far away from the national grid. As an off-grid choice, 50 W SHS is being distributed to customers in distant rustic parts of the country where grid option is difficult to access. But the SHS of the stated capacity can barely generate 0.3 to 0.4 kWh of electric energy per day, even at the optimal solar radiations. In view of this, more efforts are directed at expanding the off-grid systems to accommodate large rural households in South Africa. This thesis is dedicated to a study on the various configurations and components of PV power plant as a way to enhance electricity generations in South Africa. To this effect, different power plants were considered at SolarWatt park, University of Fort Hare with the aim to conduct a comparative analysis of the charge controllers with respect to the charge and discharge rates of their respective batteries. The grid-connected PV power generation was classified into hybrid PV and grid-assisted PV, while off-grid is a BIPV. These power plants generations were installed for the purpose of research level with a total capacity of 11.4 kW. The off-grid system is made up of HIT modules, FlexMax80 charge controller, Victron energy inverter and M-Molar battery bank. The hybrid and grid-assisted systems each consist of 15 polycrystalline modules and Microcare charge controllers. In addition, hybrid comprises SMA Sunny Island inverter and Trojan battery bank whereas grid-assisted consist of Microcare inverter and Hoppercke battery bank. The first part of the experimental work was monitored, and the meteorological parameters which are ambient temperature, solar radiation, relative humidity and wind speed, were measured and evaluated while electrical parameters includes PV current and voltage, MPPT current and voltage, battery current and voltage and inverter current and voltage were also measured and evaluated in the second part of the experiment. This lasted for a period of four years, starting from 1st January 2017 to 31st December 2020. Similarly, the second aspect was to monitor the electrical performance of the three systems and was performed for a period of six months, starting from January to June 2019. During the second experiment, hybrid and grid-assisted systems were reconfigured to function as off-grid systems. Moreover, a detailed data acquisition system designed to measure and record both meteorological and electrical parameters affecting the performance of the systems. The electrical parameters include PV current and voltage, MPPT current, battery current and voltage and inverter current and voltage. Other parameters in the measurements are; inverter efficiency, active and apparent power, while meteorological parameters include; solar irradiance, ambient temperature, relative humidity, wind speed and direction. The meteorological results show that the maximum and minimum mean amount of global solar radiation was 7.34 kWh/m2/day in December and 3.03 kWh/m2/day in June, respectively, while the average radiation and temperature for the typical year were 4.98 kWh/m2/day and 16.88 oC respectively. The solar radiations obtained are within the range in major places in South Africa. Similarly, an average wind speed of 2.5 m/s is experienced in Alice in a year and average solar radiation of 606.06 W/m2 in summer and 346.17 W/m2 in winter. The three lead-acid battery systems monitored under the electrical aspect are M-Molar, Trojan and Hoppecke battery systems. It was established that the charging current decreases gradually from 27.7 to 18.5 A for the M-Molar while Hoppecke and Trojan deceased respectively from 15 to 10 A and 23 to 13 A at the end of each phase by charging it at the maximum power point of the PV array. It was equally found that the M-Molar battery current has the highest rate of charging and quickest rate of discharging in comparison to the other two batteries. Finally, from the results gotten from this research, we may propose that the solar PV system contributes significantly to the satisfaction of the needed electricity in South Africa. , Thesis (PhD) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-08
- Authors: Apeh, Oliver Okechukwu https://orcid.org/0000-0003-4076-0613
- Date: 2021-08
- Subjects: Photovoltaic power systems , Solar energy
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/21567 , vital:48888
- Description: PVsystem has recently emerged in South Africa as a way to curb the country’s persistent shortage of electricity. A wide effort for the past few decades have targeted at study, testing and demonstration of PV power systems which was established all over the country as an appropriate measure to tackle transportation, agriculture, industry, commercial as well as domestic activities. In view of these drives, both off-grid and grid-connected PV systems are being applied. However, operating a building with an off-grid system is one of the means to providing the possibility of energy access to places far away from the national grid. As an off-grid choice, 50 W SHS is being distributed to customers in distant rustic parts of the country where grid option is difficult to access. But the SHS of the stated capacity can barely generate 0.3 to 0.4 kWh of electric energy per day, even at the optimal solar radiations. In view of this, more efforts are directed at expanding the off-grid systems to accommodate large rural households in South Africa. This thesis is dedicated to a study on the various configurations and components of PV power plant as a way to enhance electricity generations in South Africa. To this effect, different power plants were considered at SolarWatt park, University of Fort Hare with the aim to conduct a comparative analysis of the charge controllers with respect to the charge and discharge rates of their respective batteries. The grid-connected PV power generation was classified into hybrid PV and grid-assisted PV, while off-grid is a BIPV. These power plants generations were installed for the purpose of research level with a total capacity of 11.4 kW. The off-grid system is made up of HIT modules, FlexMax80 charge controller, Victron energy inverter and M-Molar battery bank. The hybrid and grid-assisted systems each consist of 15 polycrystalline modules and Microcare charge controllers. In addition, hybrid comprises SMA Sunny Island inverter and Trojan battery bank whereas grid-assisted consist of Microcare inverter and Hoppercke battery bank. The first part of the experimental work was monitored, and the meteorological parameters which are ambient temperature, solar radiation, relative humidity and wind speed, were measured and evaluated while electrical parameters includes PV current and voltage, MPPT current and voltage, battery current and voltage and inverter current and voltage were also measured and evaluated in the second part of the experiment. This lasted for a period of four years, starting from 1st January 2017 to 31st December 2020. Similarly, the second aspect was to monitor the electrical performance of the three systems and was performed for a period of six months, starting from January to June 2019. During the second experiment, hybrid and grid-assisted systems were reconfigured to function as off-grid systems. Moreover, a detailed data acquisition system designed to measure and record both meteorological and electrical parameters affecting the performance of the systems. The electrical parameters include PV current and voltage, MPPT current, battery current and voltage and inverter current and voltage. Other parameters in the measurements are; inverter efficiency, active and apparent power, while meteorological parameters include; solar irradiance, ambient temperature, relative humidity, wind speed and direction. The meteorological results show that the maximum and minimum mean amount of global solar radiation was 7.34 kWh/m2/day in December and 3.03 kWh/m2/day in June, respectively, while the average radiation and temperature for the typical year were 4.98 kWh/m2/day and 16.88 oC respectively. The solar radiations obtained are within the range in major places in South Africa. Similarly, an average wind speed of 2.5 m/s is experienced in Alice in a year and average solar radiation of 606.06 W/m2 in summer and 346.17 W/m2 in winter. The three lead-acid battery systems monitored under the electrical aspect are M-Molar, Trojan and Hoppecke battery systems. It was established that the charging current decreases gradually from 27.7 to 18.5 A for the M-Molar while Hoppecke and Trojan deceased respectively from 15 to 10 A and 23 to 13 A at the end of each phase by charging it at the maximum power point of the PV array. It was equally found that the M-Molar battery current has the highest rate of charging and quickest rate of discharging in comparison to the other two batteries. Finally, from the results gotten from this research, we may propose that the solar PV system contributes significantly to the satisfaction of the needed electricity in South Africa. , Thesis (PhD) -- Faculty of Science and Agriculture, 2021
- Full Text:
- Date Issued: 2021-08
The Training of pre-service science teachers in the integration of Information and Communication Technology integration in Science teaching: A case of two colleges of education in The Volta Region of Ghana
- Authors: Ofori, Mac-Jones
- Date: 2023
- Subjects: Teachers -- Training of , Science -- Study and teaching , Information technology -- Study and teaching
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27898 , vital:70467
- Description: The study was carried out to investigate the training of pre-service Science teachers in the integration of Information and Communication Technology (ICT) in Science teaching at two colleges of education in the Volta region of Ghana. The study aimed to recommend a framework that can be used to enhance the training in ICT integration competencies of pre-service Science teachers at colleges of education in the country. The study was underpinned by two theoretical frameworks: Rogan and Grayson’s curriculum implementation framework and Guzman and Nussbaum’s ICT integration framework and was located within the interpretive paradigm. The qualitative research approach was adopted to generate data on the types of ICT integration competences that pre-service Science teachers are trained in, the pedagogical strategies used, the support provided, and the challenges faced during the training. The study adopted the explanatory case study design. Convenience and purposive sampling were used to select the study sites and participants respectively, which consisted of two teacher education colleges, two heads of Science department, ten lecturers, and 20 pre-service Science teachers. The study’s data collection methods were semi-structured face-to-face interviews with the lecturers, focus group discussions with the pre-service Science teachers, non-participatory lesson observation, and document analysis. The data was analysed using thematic approach. The study established that pre-service Science teachers at the two colleges received training in mastering the usage of ICT tools, relating ICT to teaching; using ICT for assessment and providing feedback, creating an appropriate environment for ICT integration, and developing positive attitudes toward ICT usage. The study revealed the pedagogical strategies used for training the pre-service Science teachers in ICT integration competencies to include a standalone ICT course, demonstration, group work, self-learning and how assessment is carried out. The study also established that there was support from both within and without the college environment in training pre-service Science teachers, although this was inadequate. The major challenges found by the study to be hindering effective pre-service teacher training in ICT integration competencies were lack of technical know-how among lecturers, poor pre-service Science teachers’ backgrounds in ICT, inadequate ICT resources and infrastructure, prolonged organisational and management bureaucracy, and insufficient funding of ICT. The recommendations made included the need for upgrading infrastructure in the colleges while also upgrading lecturers’ competencies in handling ICT in the colleges. An alternative training framework for preparing pre-service Science teachers in ICT integration competencies was also proposed. , Thesis (MEd) -- Faculty of Education, 2023
- Full Text:
- Date Issued: 2023
- Authors: Ofori, Mac-Jones
- Date: 2023
- Subjects: Teachers -- Training of , Science -- Study and teaching , Information technology -- Study and teaching
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27898 , vital:70467
- Description: The study was carried out to investigate the training of pre-service Science teachers in the integration of Information and Communication Technology (ICT) in Science teaching at two colleges of education in the Volta region of Ghana. The study aimed to recommend a framework that can be used to enhance the training in ICT integration competencies of pre-service Science teachers at colleges of education in the country. The study was underpinned by two theoretical frameworks: Rogan and Grayson’s curriculum implementation framework and Guzman and Nussbaum’s ICT integration framework and was located within the interpretive paradigm. The qualitative research approach was adopted to generate data on the types of ICT integration competences that pre-service Science teachers are trained in, the pedagogical strategies used, the support provided, and the challenges faced during the training. The study adopted the explanatory case study design. Convenience and purposive sampling were used to select the study sites and participants respectively, which consisted of two teacher education colleges, two heads of Science department, ten lecturers, and 20 pre-service Science teachers. The study’s data collection methods were semi-structured face-to-face interviews with the lecturers, focus group discussions with the pre-service Science teachers, non-participatory lesson observation, and document analysis. The data was analysed using thematic approach. The study established that pre-service Science teachers at the two colleges received training in mastering the usage of ICT tools, relating ICT to teaching; using ICT for assessment and providing feedback, creating an appropriate environment for ICT integration, and developing positive attitudes toward ICT usage. The study revealed the pedagogical strategies used for training the pre-service Science teachers in ICT integration competencies to include a standalone ICT course, demonstration, group work, self-learning and how assessment is carried out. The study also established that there was support from both within and without the college environment in training pre-service Science teachers, although this was inadequate. The major challenges found by the study to be hindering effective pre-service teacher training in ICT integration competencies were lack of technical know-how among lecturers, poor pre-service Science teachers’ backgrounds in ICT, inadequate ICT resources and infrastructure, prolonged organisational and management bureaucracy, and insufficient funding of ICT. The recommendations made included the need for upgrading infrastructure in the colleges while also upgrading lecturers’ competencies in handling ICT in the colleges. An alternative training framework for preparing pre-service Science teachers in ICT integration competencies was also proposed. , Thesis (MEd) -- Faculty of Education, 2023
- Full Text:
- Date Issued: 2023
Foraging ecology of Kelp Gulls in natural and anthropogenically modified environments
- Authors: Reusch, Katharina
- Date: 2021-12
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/54106 , vital:46303
- Description: Humans are having a profound impact on the natural environment through a myriad of activities, such as land use change or direct exploitation of resources. Some species are able to adapt to these changes and thrive in deeply modified environments. They are often considered winners of global change. Among these are Kelp GullsLarus dominicanus in South Africa, which have a generalist foraging nature. Despite their abundance and potential role in the ecosystem, knowledge on their foraging ecology is limited, with no understanding of the role of natural and anthropogenic food resources during breeding. The aim of this thesis was to assess the foraging movements, diet and health of Kelp Gulls breeding in seven different colonies varying in proximity to landfills. GPS loggers were deployed on incubating adults to assess foraging trip patterns, effort, and habitats. Diet and trophic ecology of adults and chicks was determined during the breeding season by combining conventional diet analysis (i.e. stomach content samples and regurgitated pellets) with stable isotope analysis of blood plasma. Finally, population health was estimated using indices of body condition for adults and chicks, and blood and faecal parasites were examined. The first successful tracking data from Kelp Gulls in South Africa revealed that birds from all colonies spent more time foraging in natural environments (marine, coastal and terrestrial) than in anthropogenically modified ones, irrelevant of the distance to the nearest landfill, potentially reflecting prey profitability or availability around thebreeding colonies. Gulls also had higher foraging effort when foraging at sea (longer travelling distance), which might be balanced by foraging on high energy prey in themarine environment (e.g. fish). Diet and trophic ecology data confirmed the wide range of resources Kelp Gulls were capable of exploiting. Anthropogenic items were important food sources at some colonies, while annual differences in trophic level targeted were apparent at some other colonies, possibly reflecting varying predation levels on other seabirds. Diet and trophic ecology generally differed between adults and chicks, with chicks being fed a more marine, i.e. fish, and higher trophic level diet, potentially due to the higher energy content of fish being important for chick growth. Despite differences between colonies in foraging effort and diet, body condition of both adults and chicks was similar across colonies. Birds from one of the urban colonies, foraging at the local landfill, tended to have slightly higher body condition values, possibly due to the high fat content of anthropogenic items, although this was not significant. Blood parasites were very scarce, with only one genus identified, Haemoproteus spp. Parasite abundance was significantly lower in chicks than in adults, implicating that adults might get infected in areas outside the colony. Faecal smears revealed the presence of yeast cells (Candida spp.) in birds, coinciding with higher body condition values, possibly linked to foraging habitat choice, as birds might ingest yeast cells when feeding in urban areas contaminated with human excrement.Kelp Gulls breeding in South Africa forage on a wide variety of resources and habitats, with limited apparent impact on their parasite load and body condition. All colonies foraged to some extend on natural sources, although some colonies located in very urban areas seemed to depend more closely on anthropogenic items as food resource. Therefore, changes in e.g. landfill management might cause changes in population dynamics, with possible repercussions on neighbouring bird populations. Theirgeneralist foraging nature, among others, makes Kelp Gulls winners of global change and is partly responsible for their increased population numbers. As they are often perceived as pests, information on the foraging ecology is important to manage gull populations effectively. , Thesis (PhD) -- Faculty of Sciences, School of Environmental Sciences, 2021
- Full Text:
- Date Issued: 2021-12
- Authors: Reusch, Katharina
- Date: 2021-12
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/54106 , vital:46303
- Description: Humans are having a profound impact on the natural environment through a myriad of activities, such as land use change or direct exploitation of resources. Some species are able to adapt to these changes and thrive in deeply modified environments. They are often considered winners of global change. Among these are Kelp GullsLarus dominicanus in South Africa, which have a generalist foraging nature. Despite their abundance and potential role in the ecosystem, knowledge on their foraging ecology is limited, with no understanding of the role of natural and anthropogenic food resources during breeding. The aim of this thesis was to assess the foraging movements, diet and health of Kelp Gulls breeding in seven different colonies varying in proximity to landfills. GPS loggers were deployed on incubating adults to assess foraging trip patterns, effort, and habitats. Diet and trophic ecology of adults and chicks was determined during the breeding season by combining conventional diet analysis (i.e. stomach content samples and regurgitated pellets) with stable isotope analysis of blood plasma. Finally, population health was estimated using indices of body condition for adults and chicks, and blood and faecal parasites were examined. The first successful tracking data from Kelp Gulls in South Africa revealed that birds from all colonies spent more time foraging in natural environments (marine, coastal and terrestrial) than in anthropogenically modified ones, irrelevant of the distance to the nearest landfill, potentially reflecting prey profitability or availability around thebreeding colonies. Gulls also had higher foraging effort when foraging at sea (longer travelling distance), which might be balanced by foraging on high energy prey in themarine environment (e.g. fish). Diet and trophic ecology data confirmed the wide range of resources Kelp Gulls were capable of exploiting. Anthropogenic items were important food sources at some colonies, while annual differences in trophic level targeted were apparent at some other colonies, possibly reflecting varying predation levels on other seabirds. Diet and trophic ecology generally differed between adults and chicks, with chicks being fed a more marine, i.e. fish, and higher trophic level diet, potentially due to the higher energy content of fish being important for chick growth. Despite differences between colonies in foraging effort and diet, body condition of both adults and chicks was similar across colonies. Birds from one of the urban colonies, foraging at the local landfill, tended to have slightly higher body condition values, possibly due to the high fat content of anthropogenic items, although this was not significant. Blood parasites were very scarce, with only one genus identified, Haemoproteus spp. Parasite abundance was significantly lower in chicks than in adults, implicating that adults might get infected in areas outside the colony. Faecal smears revealed the presence of yeast cells (Candida spp.) in birds, coinciding with higher body condition values, possibly linked to foraging habitat choice, as birds might ingest yeast cells when feeding in urban areas contaminated with human excrement.Kelp Gulls breeding in South Africa forage on a wide variety of resources and habitats, with limited apparent impact on their parasite load and body condition. All colonies foraged to some extend on natural sources, although some colonies located in very urban areas seemed to depend more closely on anthropogenic items as food resource. Therefore, changes in e.g. landfill management might cause changes in population dynamics, with possible repercussions on neighbouring bird populations. Theirgeneralist foraging nature, among others, makes Kelp Gulls winners of global change and is partly responsible for their increased population numbers. As they are often perceived as pests, information on the foraging ecology is important to manage gull populations effectively. , Thesis (PhD) -- Faculty of Sciences, School of Environmental Sciences, 2021
- Full Text:
- Date Issued: 2021-12
Use of flow reactors for an improved synthesis of Tenofovir derivatives
- Authors: Sonti, Thembela
- Date: 2023-04
- Subjects: Antiviral agents -- South Africa , HIV infections –Treatment
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/61190 , vital:69792
- Description: Tenofovir disoproxil fumarate (TDF) is a prescription drug used to treat and prevent human immunodeficiency virus (HIV) infections. It aids in the reduction of HIV in the body, allowing the immune system to function more effectively. This reduces the risk of HIV complications, such as infections, whilst improving the quality of life. TDF belongs to the nucleotide reverse transcriptase inhibitors category of drugs. These drugs limit the ability of the reverse transcriptase, an enzyme essential for each virus to replicate itself. A reduction in the cost of HIV treatment could improve supply security and make it more accessible to patients in need. Thus, this project aims to use flow technology to achieve a guaranteed supply chain and access. In this thesis, a method for the synthesis of TDF was developed using microreactors starting from the readily available adenine. The method was adapted from the traditional batch synthesis as currently there is no literature on the synthesis of TDF in flow chemistry. The batch methods used for the synthesis of the working standards were successfully translated to flow systems. For the best results to be obtained, optimisation of the reaction temperature, reagent molar equivalents and concentration was critical. From the optimisation studies, an improvement in conversion is evident throughout all stages. The flow synthesis of the first intermediate resulted in a conversion of 100 % in N,N-dimethylformamide in 6 min residence time. This study was conducted at 200 °C, which is higher than the boiling point of the solvent with the aid of a back pressure regulator. A key reagent in the synthesis of tenofovir, namely ((tosyloxy)methyl)phosphonic acid, had to be synthesised and it was successfully produced in 96 % yield. The second intermediate was synthesised through a successful coupling reaction between (R)-9-(2-hydroxypropyl)adenine and ((tosyloxy)methyl)- phosphonic acid, which afforded a 100 % conversion of tenofovir in 20 min total residence time. The multistep synthesis of tenofovir was a success as it afforded a 65 % overall conversion. The prodrug TDF was successfully synthesised at 120 °C with a 30 min residence time, yielding a conversion of 100 %. ii | P a g e This thesis consists of four chapters. Chapter one describes the background on HIV and a literature review on HIV drugs. This chapter also demonstrates flow chemistry and microreactors in detail and different routes for the synthesis of TDF in traditional batch methods. Chapter two provides a detailed methodology for batch synthesis and flow synthesis with analytical data. 1H-NMR, 13C-NMR and FTIR spectroscopy was used to evaluate all the compounds synthesised in this chapter. Chapter three thoroughly discusses the results that were obtained graphically, showing that the flow synthesis gives better yields than batch synthesis. In chapter 4, the conclusion of the whole investigation is stated along with the future work for the preparation of TDF. , Thesis (PhD) -- Faculty of Science, School of Biomolecular and Chemical Sciences, 2023
- Full Text:
- Date Issued: 2023-04
- Authors: Sonti, Thembela
- Date: 2023-04
- Subjects: Antiviral agents -- South Africa , HIV infections –Treatment
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/61190 , vital:69792
- Description: Tenofovir disoproxil fumarate (TDF) is a prescription drug used to treat and prevent human immunodeficiency virus (HIV) infections. It aids in the reduction of HIV in the body, allowing the immune system to function more effectively. This reduces the risk of HIV complications, such as infections, whilst improving the quality of life. TDF belongs to the nucleotide reverse transcriptase inhibitors category of drugs. These drugs limit the ability of the reverse transcriptase, an enzyme essential for each virus to replicate itself. A reduction in the cost of HIV treatment could improve supply security and make it more accessible to patients in need. Thus, this project aims to use flow technology to achieve a guaranteed supply chain and access. In this thesis, a method for the synthesis of TDF was developed using microreactors starting from the readily available adenine. The method was adapted from the traditional batch synthesis as currently there is no literature on the synthesis of TDF in flow chemistry. The batch methods used for the synthesis of the working standards were successfully translated to flow systems. For the best results to be obtained, optimisation of the reaction temperature, reagent molar equivalents and concentration was critical. From the optimisation studies, an improvement in conversion is evident throughout all stages. The flow synthesis of the first intermediate resulted in a conversion of 100 % in N,N-dimethylformamide in 6 min residence time. This study was conducted at 200 °C, which is higher than the boiling point of the solvent with the aid of a back pressure regulator. A key reagent in the synthesis of tenofovir, namely ((tosyloxy)methyl)phosphonic acid, had to be synthesised and it was successfully produced in 96 % yield. The second intermediate was synthesised through a successful coupling reaction between (R)-9-(2-hydroxypropyl)adenine and ((tosyloxy)methyl)- phosphonic acid, which afforded a 100 % conversion of tenofovir in 20 min total residence time. The multistep synthesis of tenofovir was a success as it afforded a 65 % overall conversion. The prodrug TDF was successfully synthesised at 120 °C with a 30 min residence time, yielding a conversion of 100 %. ii | P a g e This thesis consists of four chapters. Chapter one describes the background on HIV and a literature review on HIV drugs. This chapter also demonstrates flow chemistry and microreactors in detail and different routes for the synthesis of TDF in traditional batch methods. Chapter two provides a detailed methodology for batch synthesis and flow synthesis with analytical data. 1H-NMR, 13C-NMR and FTIR spectroscopy was used to evaluate all the compounds synthesised in this chapter. Chapter three thoroughly discusses the results that were obtained graphically, showing that the flow synthesis gives better yields than batch synthesis. In chapter 4, the conclusion of the whole investigation is stated along with the future work for the preparation of TDF. , Thesis (PhD) -- Faculty of Science, School of Biomolecular and Chemical Sciences, 2023
- Full Text:
- Date Issued: 2023-04
Synthesis and in vitro biological studies of ursolic acid-based hybrid compounds
- Authors: Khwaza, Vuyolwethu
- Date: 2022
- Subjects: Herbal medicine , Herbs -- Therapeutic use , Antineoplastic antibiotics
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27797 , vital:69689
- Description: Ursolic acid UA, a pentacyclic triterpenoid that is commonly found in many medicinal herbs and fruits, has been identified as a potential source of therapeutic agents because of its potent biological effects, which include its potential anticancer and antimicrobial activities. However, its limited solubility, rapid metabolism and poor bioavailability inhibit its clinical applications. Numerous UA derivatives have been prepared over the past years in an effort to mitigate the drawbacks associated with UA, as new chemical entities for the treatment of various infections. There is very little progress in the discovery of efficient UA derivatives. In this study, a class of ester and amide-linked ursolic acid-based hybrid compounds fused with selected pharmaceutical scaffolds were successfully synthesized using amidation and esterification reactions and tested for antibacterial and cytotoxicity activities. Hybridizing UA with other known pharmaceutical scaffolds has the potential of overcoming its drawbacks. FT-IR, Mass Spectroscopy, and 1H13C-NMR spectroscopy were used to confirm the structures of the synthesized hybrid compounds. Among the tested ester-linked hybrid compounds in Chapter three, compounds 3.14-3.19,3.21, 3.34, 3.31, and 3.30 demonstrated significant antibacterial activities against some tested bacteria, with MIC values of 15.625 μgml. Furthermore, the in vitro cytotoxicity of these hybrids was determined using the MTT assay against three human tumor cell lines MCF7, MDA-MB-231, and HeLa cells. Compounds 3.19 and 3.34 were found to have better cytotoxic activity when compared to ursolic acid, with IC50 values of 46.99 and 48.18 μg ml respectively. Both compounds revealed more promising docking results, presenting favourable binding interactions as well as better docking energy against the MCF 7 protein target compared to the parent compound ursolic acid. In Chapter Four, among the tested amide-linked hybrid compounds, Compounds 4.17 and 4.24 demonstrated significant antibacterial activity against the majority of bacterial strains with MIC values of 15.625 gml. Compound 4.24 exhibited a MIC value of 15.625gmL against BS, SA, PV, KO, PM, and EC. Compound 4.23 was more cytotoxic to HeLa cells than ursolic acid. Furthermore, molecular docking calculations revealed that compound 4.16 strongly binds to the protein epidermal growth factor receptor while e compounds 4.17 and 4.24 showed a strong binding affinity for the methionyl-tRNA synthetase. In both cases, the hybrid compounds showed better conformational fittings in the active site of the targeted proteins as compared to the parent ursolic acid. , Thesis (MSc) -- Faculty of Science and Agriculture, 2022
- Full Text:
- Date Issued: 2022
- Authors: Khwaza, Vuyolwethu
- Date: 2022
- Subjects: Herbal medicine , Herbs -- Therapeutic use , Antineoplastic antibiotics
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27797 , vital:69689
- Description: Ursolic acid UA, a pentacyclic triterpenoid that is commonly found in many medicinal herbs and fruits, has been identified as a potential source of therapeutic agents because of its potent biological effects, which include its potential anticancer and antimicrobial activities. However, its limited solubility, rapid metabolism and poor bioavailability inhibit its clinical applications. Numerous UA derivatives have been prepared over the past years in an effort to mitigate the drawbacks associated with UA, as new chemical entities for the treatment of various infections. There is very little progress in the discovery of efficient UA derivatives. In this study, a class of ester and amide-linked ursolic acid-based hybrid compounds fused with selected pharmaceutical scaffolds were successfully synthesized using amidation and esterification reactions and tested for antibacterial and cytotoxicity activities. Hybridizing UA with other known pharmaceutical scaffolds has the potential of overcoming its drawbacks. FT-IR, Mass Spectroscopy, and 1H13C-NMR spectroscopy were used to confirm the structures of the synthesized hybrid compounds. Among the tested ester-linked hybrid compounds in Chapter three, compounds 3.14-3.19,3.21, 3.34, 3.31, and 3.30 demonstrated significant antibacterial activities against some tested bacteria, with MIC values of 15.625 μgml. Furthermore, the in vitro cytotoxicity of these hybrids was determined using the MTT assay against three human tumor cell lines MCF7, MDA-MB-231, and HeLa cells. Compounds 3.19 and 3.34 were found to have better cytotoxic activity when compared to ursolic acid, with IC50 values of 46.99 and 48.18 μg ml respectively. Both compounds revealed more promising docking results, presenting favourable binding interactions as well as better docking energy against the MCF 7 protein target compared to the parent compound ursolic acid. In Chapter Four, among the tested amide-linked hybrid compounds, Compounds 4.17 and 4.24 demonstrated significant antibacterial activity against the majority of bacterial strains with MIC values of 15.625 gml. Compound 4.24 exhibited a MIC value of 15.625gmL against BS, SA, PV, KO, PM, and EC. Compound 4.23 was more cytotoxic to HeLa cells than ursolic acid. Furthermore, molecular docking calculations revealed that compound 4.16 strongly binds to the protein epidermal growth factor receptor while e compounds 4.17 and 4.24 showed a strong binding affinity for the methionyl-tRNA synthetase. In both cases, the hybrid compounds showed better conformational fittings in the active site of the targeted proteins as compared to the parent ursolic acid. , Thesis (MSc) -- Faculty of Science and Agriculture, 2022
- Full Text:
- Date Issued: 2022
Billing system, communication strategies, and organisation change in Zimbabwe: the case of telone customers’ postpaid to prepaid migration
- Authors: Dube, Sizalobuhle
- Date: 2023-04
- Subjects: Communication , Organizational change , Organizational change -- Management
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27336 , vital:66942
- Description: This study investigated the effectiveness of the communication strategies used to implement the migration of telephone services from post-paid to prepaid billing at TelOne Zimbabwe. This study adopted the Freeman‟s stakeholder theory and the Lewin‟s change model to analyse the factors that influenced the effectiveness of the communication strategies used by TelOne before, during and after the change implementation as a way to communicate the initiative with its stakeholders. A qualitative approach was utilised and the key research methods used included document analysis, participant observation, as well as 21 face-to-face and 79 telephonic semi-structured interviews conducted with respondents from among TelOne managers, employees and the customers. The documents and respondents were purposively sampled based on the researcher‟s knowledge of their relevance in the study. The findings revealed several factors that mired effective change communication strategies such as company image, stakeholder recognition and communication centralisation. To curb these communication challenges, the study proposes Thrive organisational communication change model TOCC that encourages organisations to communicate the initiative to its relevant internal and external stakeholders considering their views and addressing factors that might hinder effective communication as a strategy to enhance successful change management. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2023
- Full Text:
- Date Issued: 2023-04
- Authors: Dube, Sizalobuhle
- Date: 2023-04
- Subjects: Communication , Organizational change , Organizational change -- Management
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/27336 , vital:66942
- Description: This study investigated the effectiveness of the communication strategies used to implement the migration of telephone services from post-paid to prepaid billing at TelOne Zimbabwe. This study adopted the Freeman‟s stakeholder theory and the Lewin‟s change model to analyse the factors that influenced the effectiveness of the communication strategies used by TelOne before, during and after the change implementation as a way to communicate the initiative with its stakeholders. A qualitative approach was utilised and the key research methods used included document analysis, participant observation, as well as 21 face-to-face and 79 telephonic semi-structured interviews conducted with respondents from among TelOne managers, employees and the customers. The documents and respondents were purposively sampled based on the researcher‟s knowledge of their relevance in the study. The findings revealed several factors that mired effective change communication strategies such as company image, stakeholder recognition and communication centralisation. To curb these communication challenges, the study proposes Thrive organisational communication change model TOCC that encourages organisations to communicate the initiative to its relevant internal and external stakeholders considering their views and addressing factors that might hinder effective communication as a strategy to enhance successful change management. , Thesis (PhD) -- Faculty of Social Sciences and Humanities, 2023
- Full Text:
- Date Issued: 2023-04
Microstructural characterization of Swift Heavy Ion (SHI) induced rotation in single crystal NiO
- Authors: Douglas-Henry, Danielle
- Date: 2021-12
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/53648 , vital:45685
- Description: Swift Heavy Ions (SHI) are characterised by having energies greater than 1 MeV per nucleon with an atomic mass greater than 6 amu. Exposure to irradiation of this type has been known to produce latent tracks in insulators. This is due to the energy loss through the material being governed by electronic excitation processes. The extent of the track formation and microstructural changes induced has been reported to be material specific. Models such as the thermal spike model have been used to explain these changes, however rough approximations are still made. A particularly under studied phenomena is the collective rotation seen in materials exposed to off-normal incidence irradiation. To date the only available experimental data is X-Ray Diffraction (XRD) spectra and surface shifts. This does not allow for depth-dependent rotation studies and very little can be deduced regarding the microstructure of the modified volume. In this study, the microstructural changes in single crystal Nickel Oxide (NiO) have been studied using electron microscopy techniques. A depth dependent investigation of the crystal rotation was performed using Selected Area Electron Diffraction (SAED), Transmission Kikuchi Diffraction (TKD) and Electron Backscatter Diffraction (EBSD). Transmission Electron Microscopy (TEM) and Scanning Transmission Electron Microscopy (STEM) were utilized to interrogate the microstructural changes facilitating the bulk rotation. Five different NiO specimens were investigated. Specimens had surfaces parallel to either the {0 0 1} or {1 1 1} planes. Ion energies used were 593 MeV, 940 MeV and 1.6 GeV, while fluences ranged from 1.0 x 1011 ions/cm² to 9.6 x 1014 ions/cm². Latent track formation in both low fluence (nonoverlapping regime) and high fluence (overlapping regime) specimens were investigated and compared. , Thesis (PhD) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2021
- Full Text: false
- Date Issued: 2021-12
- Authors: Douglas-Henry, Danielle
- Date: 2021-12
- Subjects: Port Elizabeth (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/53648 , vital:45685
- Description: Swift Heavy Ions (SHI) are characterised by having energies greater than 1 MeV per nucleon with an atomic mass greater than 6 amu. Exposure to irradiation of this type has been known to produce latent tracks in insulators. This is due to the energy loss through the material being governed by electronic excitation processes. The extent of the track formation and microstructural changes induced has been reported to be material specific. Models such as the thermal spike model have been used to explain these changes, however rough approximations are still made. A particularly under studied phenomena is the collective rotation seen in materials exposed to off-normal incidence irradiation. To date the only available experimental data is X-Ray Diffraction (XRD) spectra and surface shifts. This does not allow for depth-dependent rotation studies and very little can be deduced regarding the microstructure of the modified volume. In this study, the microstructural changes in single crystal Nickel Oxide (NiO) have been studied using electron microscopy techniques. A depth dependent investigation of the crystal rotation was performed using Selected Area Electron Diffraction (SAED), Transmission Kikuchi Diffraction (TKD) and Electron Backscatter Diffraction (EBSD). Transmission Electron Microscopy (TEM) and Scanning Transmission Electron Microscopy (STEM) were utilized to interrogate the microstructural changes facilitating the bulk rotation. Five different NiO specimens were investigated. Specimens had surfaces parallel to either the {0 0 1} or {1 1 1} planes. Ion energies used were 593 MeV, 940 MeV and 1.6 GeV, while fluences ranged from 1.0 x 1011 ions/cm² to 9.6 x 1014 ions/cm². Latent track formation in both low fluence (nonoverlapping regime) and high fluence (overlapping regime) specimens were investigated and compared. , Thesis (PhD) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2021
- Full Text: false
- Date Issued: 2021-12
Best practice psychosocial–cultural care guideline for primary caregivers of couples in the Talensi and Nabdam districts of Ghana experiencing infertility
- Authors: Kuug, Anthony Kolsabilik
- Date: 2021-04
- Subjects: Caregivers -- Infertility -- Ghana , Couples -- Infertility -- Ghana
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/51264 , vital:43258
- Description: Infertility remains a major clinical and social problem, affecting approximately one in every ten couples. The implications of infertility range from physical abuse to denial of family property, divorce, psychological problems, such as withdrawal, anxiety and depression to social isolation, scorn, rejection and stigmatisation. The health of infertile couples needs holistic attention because, while their medical and surgical needs are addressed to correct physical and physiological barriers of infertility, their psychological and emotive needs, which constitute the psychosocial aspects of infertility, need to be addressed as well. The current study explored and described the experiences of couples with infertility and primary caregivers who rendered care to couples. The study aimed to develop a best practice psychosocial-cultural care guideline for primary caregivers to enhance the management of couples experiencing infertility in Talensi and Nabdam districts of the Upper East Region in Ghana. The study followed a qualitative design while making use of explorative, descriptive contextual and interpretive ethnographic approaches. The research populations comprised couples experiencing infertility and the primary caregivers who cared for them, consisting of public health nurses and midwives. The research study comprised three phases. In Phase 1, semi-structured interviews, narrative sketching and storytelling were used to collect data on experiences of couples with infertility while semi-structured interviews were used to explore and describe the experiences of primary caregivers who cared for them. The interviews were transcribed and analysed using Tesch’s eight steps of data analysis to make sense of the data collected. The researcher ensured the validity of the study by conforming to the Lincoln and Guba’s approach to trustworthiness by using an independent coder to validate the researcher’s coding. In Phase 2, an integrative literature review was conducted to identify previous guidelines and systematic reviews regarding psychosocial–cultural care of infertility. Relevant guidelines and reviews were selected and critically appraised. Data were extracted and synthesised for the development of a best practice guideline for psychosocial–cultural care of couples experiencing infertility. An independent appraiser critically appraised relevant guidelines to ensure trustworthiness. In phase 3, the findings of Phases 1 and 2 were integrated to formulate a draft best practice guideline for psychosocial–cultural care of couples experiencing infertility. The guideline was reviewed by a six-member expert panel and modified based on their recommendations, suggestions and comments leading to the finalisation of the best practice psychosocial–cultural care guideline for primary caregivers of couples experiencing infertility in the Talensi and Nabdam districts in Ghana. , Thesis (PhD) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-04
- Authors: Kuug, Anthony Kolsabilik
- Date: 2021-04
- Subjects: Caregivers -- Infertility -- Ghana , Couples -- Infertility -- Ghana
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/51264 , vital:43258
- Description: Infertility remains a major clinical and social problem, affecting approximately one in every ten couples. The implications of infertility range from physical abuse to denial of family property, divorce, psychological problems, such as withdrawal, anxiety and depression to social isolation, scorn, rejection and stigmatisation. The health of infertile couples needs holistic attention because, while their medical and surgical needs are addressed to correct physical and physiological barriers of infertility, their psychological and emotive needs, which constitute the psychosocial aspects of infertility, need to be addressed as well. The current study explored and described the experiences of couples with infertility and primary caregivers who rendered care to couples. The study aimed to develop a best practice psychosocial-cultural care guideline for primary caregivers to enhance the management of couples experiencing infertility in Talensi and Nabdam districts of the Upper East Region in Ghana. The study followed a qualitative design while making use of explorative, descriptive contextual and interpretive ethnographic approaches. The research populations comprised couples experiencing infertility and the primary caregivers who cared for them, consisting of public health nurses and midwives. The research study comprised three phases. In Phase 1, semi-structured interviews, narrative sketching and storytelling were used to collect data on experiences of couples with infertility while semi-structured interviews were used to explore and describe the experiences of primary caregivers who cared for them. The interviews were transcribed and analysed using Tesch’s eight steps of data analysis to make sense of the data collected. The researcher ensured the validity of the study by conforming to the Lincoln and Guba’s approach to trustworthiness by using an independent coder to validate the researcher’s coding. In Phase 2, an integrative literature review was conducted to identify previous guidelines and systematic reviews regarding psychosocial–cultural care of infertility. Relevant guidelines and reviews were selected and critically appraised. Data were extracted and synthesised for the development of a best practice guideline for psychosocial–cultural care of couples experiencing infertility. An independent appraiser critically appraised relevant guidelines to ensure trustworthiness. In phase 3, the findings of Phases 1 and 2 were integrated to formulate a draft best practice guideline for psychosocial–cultural care of couples experiencing infertility. The guideline was reviewed by a six-member expert panel and modified based on their recommendations, suggestions and comments leading to the finalisation of the best practice psychosocial–cultural care guideline for primary caregivers of couples experiencing infertility in the Talensi and Nabdam districts in Ghana. , Thesis (PhD) -- Faculty of Health Sciences, 2021
- Full Text:
- Date Issued: 2021-04
Development of a strategy to promote prenatal physical activity participation among women in Buffalo City Municipality, South Africa
- Okafor, Uchenna Benedine https://orcid.org/0000-0002-0435-2041
- Authors: Okafor, Uchenna Benedine https://orcid.org/0000-0002-0435-2041
- Date: 2022-03
- Subjects: Prenatal care , Exercise for pregnant women
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22919 , vital:53218
- Description: Research has proven that prenatal physical activity practice is associated with multiple health benefits; however, most women in South Africa rarely participate in prenatal physical activity. In contrast to more developed countries, there is dearth of research focusing specifically on prenatal physical activity and exercise among South African women. Nevertheless, in order to effectively, and strategically promote such prenatal activity, such information is important to plan for an intervention strategy. The main aim of this study was to assess the level, patterns, and associated factors of prenatal physical activity; beliefs, knowledge, attitudes, perceived benefits, and sources of information women received during pregnancy; and, furthermore, to develop an effective and relevant intervention strategy to facilitate the participation in this particular activity in Buffalo City Municipality, Eastern Cape, South Africa. Methods The study was a mixed-method, cross-sectional study design with both quantitative and qualitative data collection and analyses. The sequential explanatory design was adopted to merge and mix different datasets to be collected and analysed. The quantitative data involved a convenient sample of 1082 pregnant women in 12 randomly selected primary healthcare clinics offering antenatal health services in Buffalo City, Eastern Cape. The Pregnancy Physical Activity Questionnaire was interviewer-administered to women at each antenatal health clinic on pre-specified days, in a designated room allocated to the primary researcher by the health facility manager. The descriptive statistics were frequency distribution, percentages, mean and standard deviation. Furthermore, the bivariate and multivariate analyses were performed on two categories of participants, namely inactive or active, to determine the factors affecting prenatal physical activity behaviour. Furthermore, multiple logistic regression analyses were used to assess associations between physical activity and the predictor variables during pregnancy. Adjusted odds ratios with 95% confidence interval were applied to estimate factors associated with physical activity levels, and the associations between prenatal physical activity levels and socio-demographic, lifestyle, and obstetrics characteristics were determined using a chi-squared analyses. The significance level was set at p = 0.05. In addition, a qualitative descriptive approach was applied, using semi-structured face-to-face interviews with 15 purposively selected pregnant women, as well as 17 midwives offering antenatal health-care services to pregnant women in the 12 selected healthcare clinics. Qualitative data were analysed using a thematic content analysis. To develop the physical activity strategy for the promotion of prenatal physical activity practice, three frameworks were applied, namely the Strength, Weakness, Opportunity and Threat (SWOT), the Political, Economic Growth, Socio-Cultural, Technological, Laws and Environmental (PESTLE), and, lastly, the Build, Overcome, Explore and Minimise (BOEM) analytical frameworks. To facilitate the validation of the strategy, the findings were additionally analysed, after which, appropriate intervention strategies promoting prenatal physical activity were developed by again using the SWOT and PESTLE analytical strategic frameworks. This process involved a purposive sampling of seven experts with knowledge of and a proven academic and scholarly background in prenatal physical activity and maternal health. Next, the developed physical activity strategy was presented to various stakeholders, which included six primary healthcare managers, two midwives, and pregnant women purposively selected in each of the 12 chosen antenatal health clinics for the validation process. The stakeholders discussed, deliberated on, and provided comments and opinions of the feasibility and implementation of the developed prenatal physical activity for promotion of physical activity practices in the Eastern Cape Province. Results The findings of this particular study demonstrated low levels of prenatal physical activity among pregnant women, and, further indicated that the most preferred form of activity was light-intensity and household activities. Only 278 of the women (25.7%) met recommendations for prenatal activity (≥150 min moderate intensity exercise per week). The average time spent in moderate–vigorous physical activity was 151.6 min (95% CI: 147.2– 156.0). Most of the women participated in light exercises with a mean of 65.9% (95% CI: 64.8–67.0), and 47.6% (95% CI: 46.3–48.9) participated in household activities. The majority of the women did not receive physical activity advice during prenatal care sessions (64.7%). Lower age (<19 years) (adjusted odd ratio (AOR) = 0.3; CI: 0.16–0.76), semi-urban residence (AOR = 0.8; CI: 0.55–1.03), lower educational level (AOR = 0.5; CI: 0.20–0.71), unemployment (AOR = 0.5; CI: 0.29–0.77) and nulliparity (AOR = 0.6; CI: 0.28–1.31) were negatively associated with prenatal physical activity, while prenatal physical activity was positively associated with starting physical activity in the first trimester (AOR = 1.9; CI: 1.06–3.31) compared to other trimesters. In addition, the pregnant women were aware of the safety (88.2%) and benefits of physical activity for both mother and baby (79.6%), improved labour and delivery (93.1%), promote energy (89.0%), and should be discontinued when tired (76.6%). However, they also held the contradictory belief that pregnancy is “a time to rest” (56.5%). Furthermore, the most common sources of information about prenatal physical activity were the media, television, the radio and Internet-based websites (70.2%). Most women affirmed that prenatal physical activity reduced infant weight (61.4%), lessen moodiness (90.4), decreased risk of gestational diabetes mellitus (92.9%), pregnancy-induced hypertension (92.5%), and complications at birth (97.8%), while common negative perceptions included musculoskeletal discomfort (82.7%), and back pain (85.7%). The majority of women indicated that prenatal physical activity improved self-image (95.7%), sleep patterns (94.2%), and respiratory function (95.8%). The results from the quantitative data revealed that the major modifiable barriers to prenatal physical activity were tiredness (73.3%), lack of advice from healthcare professionals (nurses/midwives) (64.7%), low energy (64.5%), and non-accessibility to physical activity facilities (63.0%). The results were confirmed in the qualitative data, based on the Ecological Model, in which women also mentioned tiredness, work and household responsibilities, a lack of motivation, and the lack of physical activity advice and information on the relevant recommendations and guidelines. Overall, 62.4% women had high knowledge regarding prenatal physical activity; and half of the women showed a positive attitude toward it (50.1%). Whilst participants had knowledge of other types of antenatal exercises, 80.9% of the women had no knowledge of swimming exercise. Negative attitudes towards physical activity included the feeling of tiredness (67.7%), lack of interest (64.8%), and inadequate information on physical activity (59.5%). In addition, the study highlighted that midwives rarely educate and counsel pregnant women about prenatal physical activity during scheduled antenatal visits, which was attributed largely to the shortage of midwives handling many responsibilities at clinics. Nevertheless, the midwives did express a willingness to provide effective physical activity education and counselling on prenatal physical activity, if supported by relevant training and workshops. Furthermore, they further recommended the use of the Mom Connect application, which is a technological device designed by the National Department of Health, to distribute relevant information about maternal and child health. The prenatal physical activity strategies developed to address the above-mentioned and other barriers associated with prenatal physical activity include the use of scientific and technological innovations to provide basic information on prenatal physical activity to pregnant women by means of Mom Connect, and, by collaborating with the various cellphone and network companies in South Africa. Another strategy was to integrate prenatal physical activity training into the curricula of the existing higher institutions of learning that provide teaching of maternal health in the Eastern Cape Province. Additional strategies included the documentation and subsequent clarification of misconceptions about the safety concerns often associated with prenatal physical activity by making the documents accessible to all women at the clinics in the form of a small pamphlet or booklet. Lastly, stakeholders suggested that the government offer periodic prenatal physical activity campaigns, which should be presented in local community town halls and clinics and by other stakeholders to address the current lack of awareness and effectively eliminate misrepresentations and falsehoods around the safety of prenatal physical activity within geographical setting of the Eastern Cape Province. Conclusion Despite the advantages of prenatal physical activity practices, most pregnant women in South Africa do not participate in moderate-intensity physical activity. Notably, while women perceive prenatal physical activity as beneficial to both mother and baby, such theoretical knowledge is not easily translatable into practice. The predominant sources of information on prenatal physical activity are the television, the radio, and other media, which may be potentially misleading or contradictory to evidence-based physical activity practice. Furthermore, tiredness, a lack of time, work and household responsibilities, and a lack of motivation were major modifiable barriers to prenatal physical activity by the women. In addition, pregnant women rarely receive information on prenatal physical activity. Consequently, to address the needs of the pregnant women as highlighted in this study, a prenatal physical activity intervention strategy was developed and validated by key stakeholders to promote prenatal physical activity and exercise practice among women, taken in account the local context. , Thesis (PhD) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-03
- Authors: Okafor, Uchenna Benedine https://orcid.org/0000-0002-0435-2041
- Date: 2022-03
- Subjects: Prenatal care , Exercise for pregnant women
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/22919 , vital:53218
- Description: Research has proven that prenatal physical activity practice is associated with multiple health benefits; however, most women in South Africa rarely participate in prenatal physical activity. In contrast to more developed countries, there is dearth of research focusing specifically on prenatal physical activity and exercise among South African women. Nevertheless, in order to effectively, and strategically promote such prenatal activity, such information is important to plan for an intervention strategy. The main aim of this study was to assess the level, patterns, and associated factors of prenatal physical activity; beliefs, knowledge, attitudes, perceived benefits, and sources of information women received during pregnancy; and, furthermore, to develop an effective and relevant intervention strategy to facilitate the participation in this particular activity in Buffalo City Municipality, Eastern Cape, South Africa. Methods The study was a mixed-method, cross-sectional study design with both quantitative and qualitative data collection and analyses. The sequential explanatory design was adopted to merge and mix different datasets to be collected and analysed. The quantitative data involved a convenient sample of 1082 pregnant women in 12 randomly selected primary healthcare clinics offering antenatal health services in Buffalo City, Eastern Cape. The Pregnancy Physical Activity Questionnaire was interviewer-administered to women at each antenatal health clinic on pre-specified days, in a designated room allocated to the primary researcher by the health facility manager. The descriptive statistics were frequency distribution, percentages, mean and standard deviation. Furthermore, the bivariate and multivariate analyses were performed on two categories of participants, namely inactive or active, to determine the factors affecting prenatal physical activity behaviour. Furthermore, multiple logistic regression analyses were used to assess associations between physical activity and the predictor variables during pregnancy. Adjusted odds ratios with 95% confidence interval were applied to estimate factors associated with physical activity levels, and the associations between prenatal physical activity levels and socio-demographic, lifestyle, and obstetrics characteristics were determined using a chi-squared analyses. The significance level was set at p = 0.05. In addition, a qualitative descriptive approach was applied, using semi-structured face-to-face interviews with 15 purposively selected pregnant women, as well as 17 midwives offering antenatal health-care services to pregnant women in the 12 selected healthcare clinics. Qualitative data were analysed using a thematic content analysis. To develop the physical activity strategy for the promotion of prenatal physical activity practice, three frameworks were applied, namely the Strength, Weakness, Opportunity and Threat (SWOT), the Political, Economic Growth, Socio-Cultural, Technological, Laws and Environmental (PESTLE), and, lastly, the Build, Overcome, Explore and Minimise (BOEM) analytical frameworks. To facilitate the validation of the strategy, the findings were additionally analysed, after which, appropriate intervention strategies promoting prenatal physical activity were developed by again using the SWOT and PESTLE analytical strategic frameworks. This process involved a purposive sampling of seven experts with knowledge of and a proven academic and scholarly background in prenatal physical activity and maternal health. Next, the developed physical activity strategy was presented to various stakeholders, which included six primary healthcare managers, two midwives, and pregnant women purposively selected in each of the 12 chosen antenatal health clinics for the validation process. The stakeholders discussed, deliberated on, and provided comments and opinions of the feasibility and implementation of the developed prenatal physical activity for promotion of physical activity practices in the Eastern Cape Province. Results The findings of this particular study demonstrated low levels of prenatal physical activity among pregnant women, and, further indicated that the most preferred form of activity was light-intensity and household activities. Only 278 of the women (25.7%) met recommendations for prenatal activity (≥150 min moderate intensity exercise per week). The average time spent in moderate–vigorous physical activity was 151.6 min (95% CI: 147.2– 156.0). Most of the women participated in light exercises with a mean of 65.9% (95% CI: 64.8–67.0), and 47.6% (95% CI: 46.3–48.9) participated in household activities. The majority of the women did not receive physical activity advice during prenatal care sessions (64.7%). Lower age (<19 years) (adjusted odd ratio (AOR) = 0.3; CI: 0.16–0.76), semi-urban residence (AOR = 0.8; CI: 0.55–1.03), lower educational level (AOR = 0.5; CI: 0.20–0.71), unemployment (AOR = 0.5; CI: 0.29–0.77) and nulliparity (AOR = 0.6; CI: 0.28–1.31) were negatively associated with prenatal physical activity, while prenatal physical activity was positively associated with starting physical activity in the first trimester (AOR = 1.9; CI: 1.06–3.31) compared to other trimesters. In addition, the pregnant women were aware of the safety (88.2%) and benefits of physical activity for both mother and baby (79.6%), improved labour and delivery (93.1%), promote energy (89.0%), and should be discontinued when tired (76.6%). However, they also held the contradictory belief that pregnancy is “a time to rest” (56.5%). Furthermore, the most common sources of information about prenatal physical activity were the media, television, the radio and Internet-based websites (70.2%). Most women affirmed that prenatal physical activity reduced infant weight (61.4%), lessen moodiness (90.4), decreased risk of gestational diabetes mellitus (92.9%), pregnancy-induced hypertension (92.5%), and complications at birth (97.8%), while common negative perceptions included musculoskeletal discomfort (82.7%), and back pain (85.7%). The majority of women indicated that prenatal physical activity improved self-image (95.7%), sleep patterns (94.2%), and respiratory function (95.8%). The results from the quantitative data revealed that the major modifiable barriers to prenatal physical activity were tiredness (73.3%), lack of advice from healthcare professionals (nurses/midwives) (64.7%), low energy (64.5%), and non-accessibility to physical activity facilities (63.0%). The results were confirmed in the qualitative data, based on the Ecological Model, in which women also mentioned tiredness, work and household responsibilities, a lack of motivation, and the lack of physical activity advice and information on the relevant recommendations and guidelines. Overall, 62.4% women had high knowledge regarding prenatal physical activity; and half of the women showed a positive attitude toward it (50.1%). Whilst participants had knowledge of other types of antenatal exercises, 80.9% of the women had no knowledge of swimming exercise. Negative attitudes towards physical activity included the feeling of tiredness (67.7%), lack of interest (64.8%), and inadequate information on physical activity (59.5%). In addition, the study highlighted that midwives rarely educate and counsel pregnant women about prenatal physical activity during scheduled antenatal visits, which was attributed largely to the shortage of midwives handling many responsibilities at clinics. Nevertheless, the midwives did express a willingness to provide effective physical activity education and counselling on prenatal physical activity, if supported by relevant training and workshops. Furthermore, they further recommended the use of the Mom Connect application, which is a technological device designed by the National Department of Health, to distribute relevant information about maternal and child health. The prenatal physical activity strategies developed to address the above-mentioned and other barriers associated with prenatal physical activity include the use of scientific and technological innovations to provide basic information on prenatal physical activity to pregnant women by means of Mom Connect, and, by collaborating with the various cellphone and network companies in South Africa. Another strategy was to integrate prenatal physical activity training into the curricula of the existing higher institutions of learning that provide teaching of maternal health in the Eastern Cape Province. Additional strategies included the documentation and subsequent clarification of misconceptions about the safety concerns often associated with prenatal physical activity by making the documents accessible to all women at the clinics in the form of a small pamphlet or booklet. Lastly, stakeholders suggested that the government offer periodic prenatal physical activity campaigns, which should be presented in local community town halls and clinics and by other stakeholders to address the current lack of awareness and effectively eliminate misrepresentations and falsehoods around the safety of prenatal physical activity within geographical setting of the Eastern Cape Province. Conclusion Despite the advantages of prenatal physical activity practices, most pregnant women in South Africa do not participate in moderate-intensity physical activity. Notably, while women perceive prenatal physical activity as beneficial to both mother and baby, such theoretical knowledge is not easily translatable into practice. The predominant sources of information on prenatal physical activity are the television, the radio, and other media, which may be potentially misleading or contradictory to evidence-based physical activity practice. Furthermore, tiredness, a lack of time, work and household responsibilities, and a lack of motivation were major modifiable barriers to prenatal physical activity by the women. In addition, pregnant women rarely receive information on prenatal physical activity. Consequently, to address the needs of the pregnant women as highlighted in this study, a prenatal physical activity intervention strategy was developed and validated by key stakeholders to promote prenatal physical activity and exercise practice among women, taken in account the local context. , Thesis (PhD) -- Faculty of Health Sciences, 2022
- Full Text:
- Date Issued: 2022-03
A critical assessment of credit provision governance in South Africa with a focus on balancing the rights and responsibilities of credit providers and consumers under Section 129 of the National Credit Act 34 of 2005
- Batchelor, Bronwyn Le Ann https://orcid.org/0000-0001-7300-131X
- Authors: Batchelor, Bronwyn Le Ann https://orcid.org/0000-0001-7300-131X
- Date: 2022-05
- Subjects: Debtor and creditor -- South Africa , Credit control -- Law and legislation -- South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26715 , vital:65967
- Description: The National Credit Act of 2005 (the NCA), described as the fourth generation of consumer protection legislation in South Africa, is the product of an initiative by the Department of Trade and Industry to address the shortcomings of the third generation of consumer protection legislation, being the Usury Act 73 of 1968 and the Credit Agreements Act 75 of 1980. The NCA seeks to unify legislation and departs radically from the old dispensation. Its aims are, inter alia, to provide a fair and non-discriminatory marketplace, to prohibit unfair credit practices and reckless lending, to establish national norms and standards relating to consumer credit and to promote a consistent enforcement framework relating to consumer credit. Through enactment of the NCA the government appears to have focused on the protection of consumers through pre-enforcement procedures, prohibitions on reckless lending practices, prevention of over-indebtedness, alleviation of over indebtedness, and an array of other measures. This protection is deemed necessary due to the relative unequal bargaining power between the credit provider (provider) and the consumer at the time of conclusion of an agreement. This consumer protection has, however, sometimes come at the cost of provider protection. Despite these endeavours, there is still the inevitably common occurrence of breach of the agreement by consumers and the ensuing recovery process available to providers. The relationship between the two major role players – the provider and consumer - is the epicentre of any discussion, theory or legislative enactment pertaining to credit. This study commences with an examination of the historical background and rationale for the NCA, putting into context the rules and regulations which govern the relationship between the parties when an agreement is breached as well as the remedies and recourses that are available to the aggrieved party in terms of the NCA. The common law, which acts as a stabiliser especially when there are legislative changes, is examined in relation to preenforcement procedures, breach and the remedies as affected by the NCA. The equitable balancing of the rights and responsibilities of these two major role players is essential to the continued well-being of not only the parties but also the credit industry and economy as a whole. The most common way for individuals to purchase any large asset like a home or motor vehicle is to approach a financial institution for provision of a loan or credit agreement. To protect its interest, the financial institution would normally register a mortgage bond over the property or hold the title of the motor vehicle until all instalments have been settled. The problem arises when the consumer defaults on repayment of the loan or credit agreement. The financial institution would then be forced to institute legal proceedings to for example foreclose on the bond and repossess the property or motor vehicle. The preenforcement procedure finds itself in the centre of the tug of war between the parties in that this is the area and time that both parties require their rights and interests to be protected. The pre-enforcement procedures determine to a large extent, if properly implemented, how many agreements are seen to successful finalisation versus the alternative of those being cancelled and / or enforcement pursued through litigation by the provider. Successful implementation of agreements and repayment of debt would support a healthy credit industry and therefore, a strong economy. This is also the favoured outcome by the NCA. Section 129 of the NCA encapsulates the pre-enforcement procedure and thus determines balancing the parties’ rights and responsibilities through its interpretation and application. The section, however, would appear to fall short in that the delivery requirement of the notice is not adequately defined and has therefore resulted in many disputes, interpretations and two subsequent amendments to the section by the National Credit Amendment Act of 2014 and 2019. The purpose of this study is to critically analyse section 129 of the NCA and determine if the rights of both the consumer and provider have been equally protected, with particular reference to the burden of bringing the section 129 notice to the attention of the consumer. The question posed by all parties involved is always inevitably: Must the section 129 notice come to the actual knowledge of the consumer in order for it to be valid? The answer to this question has varied between two schools of thought. The first school of thought, being the pro-provider approach, answers the question in the negative and holds that as long as the provider has met certain delivery requirements their duty has been fulfilled whether or not the consumer actually receives the notice. The second school of thought, being the pro-consumer approach, answers the questions in the affirmative and requires the provider to carry the burden of ensuring the consumer actually receives the notice in order for it to be valid. There are numerous reasons in support of both schools of thought. It is hoped that this study will make a helpful contribution to the balanced interpretation of section 129. The study aims to provide a consistent interpretation of the section whilst balancing the rights of the consumer and provider respectively. , Thesis (LLD) -- Faculty of Law, 2022
- Full Text:
- Date Issued: 2022-05
- Authors: Batchelor, Bronwyn Le Ann https://orcid.org/0000-0001-7300-131X
- Date: 2022-05
- Subjects: Debtor and creditor -- South Africa , Credit control -- Law and legislation -- South Africa
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/26715 , vital:65967
- Description: The National Credit Act of 2005 (the NCA), described as the fourth generation of consumer protection legislation in South Africa, is the product of an initiative by the Department of Trade and Industry to address the shortcomings of the third generation of consumer protection legislation, being the Usury Act 73 of 1968 and the Credit Agreements Act 75 of 1980. The NCA seeks to unify legislation and departs radically from the old dispensation. Its aims are, inter alia, to provide a fair and non-discriminatory marketplace, to prohibit unfair credit practices and reckless lending, to establish national norms and standards relating to consumer credit and to promote a consistent enforcement framework relating to consumer credit. Through enactment of the NCA the government appears to have focused on the protection of consumers through pre-enforcement procedures, prohibitions on reckless lending practices, prevention of over-indebtedness, alleviation of over indebtedness, and an array of other measures. This protection is deemed necessary due to the relative unequal bargaining power between the credit provider (provider) and the consumer at the time of conclusion of an agreement. This consumer protection has, however, sometimes come at the cost of provider protection. Despite these endeavours, there is still the inevitably common occurrence of breach of the agreement by consumers and the ensuing recovery process available to providers. The relationship between the two major role players – the provider and consumer - is the epicentre of any discussion, theory or legislative enactment pertaining to credit. This study commences with an examination of the historical background and rationale for the NCA, putting into context the rules and regulations which govern the relationship between the parties when an agreement is breached as well as the remedies and recourses that are available to the aggrieved party in terms of the NCA. The common law, which acts as a stabiliser especially when there are legislative changes, is examined in relation to preenforcement procedures, breach and the remedies as affected by the NCA. The equitable balancing of the rights and responsibilities of these two major role players is essential to the continued well-being of not only the parties but also the credit industry and economy as a whole. The most common way for individuals to purchase any large asset like a home or motor vehicle is to approach a financial institution for provision of a loan or credit agreement. To protect its interest, the financial institution would normally register a mortgage bond over the property or hold the title of the motor vehicle until all instalments have been settled. The problem arises when the consumer defaults on repayment of the loan or credit agreement. The financial institution would then be forced to institute legal proceedings to for example foreclose on the bond and repossess the property or motor vehicle. The preenforcement procedure finds itself in the centre of the tug of war between the parties in that this is the area and time that both parties require their rights and interests to be protected. The pre-enforcement procedures determine to a large extent, if properly implemented, how many agreements are seen to successful finalisation versus the alternative of those being cancelled and / or enforcement pursued through litigation by the provider. Successful implementation of agreements and repayment of debt would support a healthy credit industry and therefore, a strong economy. This is also the favoured outcome by the NCA. Section 129 of the NCA encapsulates the pre-enforcement procedure and thus determines balancing the parties’ rights and responsibilities through its interpretation and application. The section, however, would appear to fall short in that the delivery requirement of the notice is not adequately defined and has therefore resulted in many disputes, interpretations and two subsequent amendments to the section by the National Credit Amendment Act of 2014 and 2019. The purpose of this study is to critically analyse section 129 of the NCA and determine if the rights of both the consumer and provider have been equally protected, with particular reference to the burden of bringing the section 129 notice to the attention of the consumer. The question posed by all parties involved is always inevitably: Must the section 129 notice come to the actual knowledge of the consumer in order for it to be valid? The answer to this question has varied between two schools of thought. The first school of thought, being the pro-provider approach, answers the question in the negative and holds that as long as the provider has met certain delivery requirements their duty has been fulfilled whether or not the consumer actually receives the notice. The second school of thought, being the pro-consumer approach, answers the questions in the affirmative and requires the provider to carry the burden of ensuring the consumer actually receives the notice in order for it to be valid. There are numerous reasons in support of both schools of thought. It is hoped that this study will make a helpful contribution to the balanced interpretation of section 129. The study aims to provide a consistent interpretation of the section whilst balancing the rights of the consumer and provider respectively. , Thesis (LLD) -- Faculty of Law, 2022
- Full Text:
- Date Issued: 2022-05
Establishment of human OCT4 as a putative HSP90 client protein: a case for HSP90 chaperoning pluripotency
- Authors: Sterrenberg, Jason Neville
- Date: 2015
- Subjects: Induced pluripotent stem cells , Heat shock proteins , Stem cells , Transcription factors , Molecular chaperones
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/194010 , vital:45415 , 10.21504/10962/194010
- Description: The therapeutic potential of stem cells is already being harnessed in clinical trails. Of even greater therapeutic potential has been the discovery of mechanisms to reprogram differentiated cells into a pluripotent stem cell-like state known as induced pluripotent stem cells (iPSCs). Stem cell nature is governed and maintained by a hierarchy of transcription factors, the apex of which is OCT4. Although much research has elucidated the transcriptional regulation of OCT4, OCT4 regulated gene expression profiles and OCT4 transcriptional activation mechanisms in both stem cell biology and cellular reprogramming to iPSCs, the fundamental biochemistry surrounding the OCT4 transcription factor remains largely unknown. In order to analyze the biochemical relationship between HSP90 and human OCT4 we developed an exogenous active human OCT4 expression model with human OCT4 under transcriptional control of a constitutive promoter. We identified the direct interaction between HSP90 and human OCT4 despite the fact that the proteins predominantly display differential subcellular localizations. We show that HSP90 inhibition resulted in degradation of human OCT4 via the ubiquitin proteasome degradation pathway. As human OCT4 and HSP90 did not interact in the nucleus, we suggest that HSP90 functions in the cytoplasmic stabilization of human OCT4. Our analysis suggests HSP90 inhibition inhibits the transcriptional activity of human OCT4 dimers without affecting monomeric OCT4 activity. Additionally our data suggests that the HSP90 and human OCT4 complex is modulated by phosphorylation events either promoting or abrogating the interaction between HSP90 and human OCT4. Our data suggest that human OCT4 displays the characteristics describing HSP90 client proteins, therefore we identify human OCT4 as a putative HSP90 client protein. The regulation of the transcription factor OCT4 by HSP90 provides fundamental insights into the complex biochemistry of stem cell biology. This may also be suggestive that HSP90 not only regulates stem cell biology by maintaining routine cellular homeostasis but additionally through the direct regulation of pluripotency factors. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2015
- Full Text:
- Date Issued: 2015
- Authors: Sterrenberg, Jason Neville
- Date: 2015
- Subjects: Induced pluripotent stem cells , Heat shock proteins , Stem cells , Transcription factors , Molecular chaperones
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/194010 , vital:45415 , 10.21504/10962/194010
- Description: The therapeutic potential of stem cells is already being harnessed in clinical trails. Of even greater therapeutic potential has been the discovery of mechanisms to reprogram differentiated cells into a pluripotent stem cell-like state known as induced pluripotent stem cells (iPSCs). Stem cell nature is governed and maintained by a hierarchy of transcription factors, the apex of which is OCT4. Although much research has elucidated the transcriptional regulation of OCT4, OCT4 regulated gene expression profiles and OCT4 transcriptional activation mechanisms in both stem cell biology and cellular reprogramming to iPSCs, the fundamental biochemistry surrounding the OCT4 transcription factor remains largely unknown. In order to analyze the biochemical relationship between HSP90 and human OCT4 we developed an exogenous active human OCT4 expression model with human OCT4 under transcriptional control of a constitutive promoter. We identified the direct interaction between HSP90 and human OCT4 despite the fact that the proteins predominantly display differential subcellular localizations. We show that HSP90 inhibition resulted in degradation of human OCT4 via the ubiquitin proteasome degradation pathway. As human OCT4 and HSP90 did not interact in the nucleus, we suggest that HSP90 functions in the cytoplasmic stabilization of human OCT4. Our analysis suggests HSP90 inhibition inhibits the transcriptional activity of human OCT4 dimers without affecting monomeric OCT4 activity. Additionally our data suggests that the HSP90 and human OCT4 complex is modulated by phosphorylation events either promoting or abrogating the interaction between HSP90 and human OCT4. Our data suggest that human OCT4 displays the characteristics describing HSP90 client proteins, therefore we identify human OCT4 as a putative HSP90 client protein. The regulation of the transcription factor OCT4 by HSP90 provides fundamental insights into the complex biochemistry of stem cell biology. This may also be suggestive that HSP90 not only regulates stem cell biology by maintaining routine cellular homeostasis but additionally through the direct regulation of pluripotency factors. , Thesis (PhD) -- Faculty of Science, Biochemistry and Microbiology, 2015
- Full Text:
- Date Issued: 2015
International legal protection of women's reproductive rights: a comparative analysis of abortion laws and policies in four jurisdictions-Nigeria, Ghana, South Africa and U.S.A.
- Authors: Abiodun, Adeleke Funminiyi
- Date: 2010-10
- Subjects: Abortion -- Law and legislation , Reproductive right
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/25839 , vital:64491
- Description: The subject matter of abortion law is extremely broad and multi-disciplinary. While naturally having its basis in criminal and constitutional law of individual states, the global development of abortion discourse has been influenced by the need to protect the reproductive rights of women as a sub-set of international human rights laws; thereby advocating not only the decriminalisation of abortion but also, that individual State should take affirmative actions in promoting abortion as a right for every woman. However, that induced abortion is a punishable criminal act or a “protectable” woman’s reproductive right remains controversial due to the plethora of perspectives, beliefs and reservations held by different groups of people which are multi-dimensional and contradictory. This thesis therefore attempts a comparative study of abortion laws and policies in four jurisdictions: Nigeria and Ghana, operating criminalised abortion laws, South Africa and United States which operate liberalised/permissive abortion laws and policies. The study basically examines the legal status and reproductive rights of women to legal and safe abortion within the existing legal framework of national laws of the four selected jurisdictions vis-à-vis the legal protection offered by various international instruments on human rights. While we show that strict and restrictive abortion laws, and also, failure of States to create conditions for safe abortion constitute infractions of the reproductive rights of women, we submit further that over-liberalisation of abortion laws and policies could also amount to infringement of the basic rights of other people, thus there is need to ensure a legal and acceptable balance. The study finally acknowledges the role of international human rights laws in the protection of women’s right to legal and safe abortion but asserts that there can be no universally acceptable morality to which the whole world could subsume in term of women’s right to abortion due to the interplay of socio-cultural, religious, and moral affiliations of the people in different communities. , Thesis (LLD) -- Faculty of Law, 2010
- Full Text:
- Date Issued: 2010-10
- Authors: Abiodun, Adeleke Funminiyi
- Date: 2010-10
- Subjects: Abortion -- Law and legislation , Reproductive right
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/25839 , vital:64491
- Description: The subject matter of abortion law is extremely broad and multi-disciplinary. While naturally having its basis in criminal and constitutional law of individual states, the global development of abortion discourse has been influenced by the need to protect the reproductive rights of women as a sub-set of international human rights laws; thereby advocating not only the decriminalisation of abortion but also, that individual State should take affirmative actions in promoting abortion as a right for every woman. However, that induced abortion is a punishable criminal act or a “protectable” woman’s reproductive right remains controversial due to the plethora of perspectives, beliefs and reservations held by different groups of people which are multi-dimensional and contradictory. This thesis therefore attempts a comparative study of abortion laws and policies in four jurisdictions: Nigeria and Ghana, operating criminalised abortion laws, South Africa and United States which operate liberalised/permissive abortion laws and policies. The study basically examines the legal status and reproductive rights of women to legal and safe abortion within the existing legal framework of national laws of the four selected jurisdictions vis-à-vis the legal protection offered by various international instruments on human rights. While we show that strict and restrictive abortion laws, and also, failure of States to create conditions for safe abortion constitute infractions of the reproductive rights of women, we submit further that over-liberalisation of abortion laws and policies could also amount to infringement of the basic rights of other people, thus there is need to ensure a legal and acceptable balance. The study finally acknowledges the role of international human rights laws in the protection of women’s right to legal and safe abortion but asserts that there can be no universally acceptable morality to which the whole world could subsume in term of women’s right to abortion due to the interplay of socio-cultural, religious, and moral affiliations of the people in different communities. , Thesis (LLD) -- Faculty of Law, 2010
- Full Text:
- Date Issued: 2010-10
An in-depth investigation of an early literacy intervention in Grade R in the Eastern Cape Province, South Africa
- Authors: Hodgskiss, Jennifer Adelé
- Date: 2023-03-29
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/366222 , vital:65844
- Description: Thesis embargoed. Expected release date early 2025. , Thesis (PhD) -- Faculty of Education, Education, 2023
- Full Text:
- Date Issued: 2023-03-29
- Authors: Hodgskiss, Jennifer Adelé
- Date: 2023-03-29
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Doctoral theses , text
- Identifier: http://hdl.handle.net/10962/366222 , vital:65844
- Description: Thesis embargoed. Expected release date early 2025. , Thesis (PhD) -- Faculty of Education, Education, 2023
- Full Text:
- Date Issued: 2023-03-29
Effect of pomegranate (Punica granatum L) peel powder meal on growth performance, gut integrity, haemato-biochemical indices, meat, and bone quality of broiler chickens
- Akuru, Eunice Amaka https://orcid.org/0000-0002-3093-0247
- Authors: Akuru, Eunice Amaka https://orcid.org/0000-0002-3093-0247
- Date: 2022-04
- Subjects: Broilers (Chickens) , Meat -- Quality
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23611 , vital:58218
- Description: The objective of the current study was to investigate the overall response of broiler birds to varying dietary levels of pomegranate (Punica granatum L) peel powder meal (PPPM). A total of 432-day-old Cobb 500 broiler chicks were randomly divided into six experimental groups of four replications with 18 birds per replicate in a completely randomized design (CRD). The birds were fed isonitrogenous and isocaloric experimental diets designated as: T1-control diet with 0percent additives (negative control; NEGCON); T2- control diet supplemented with α-tocopherol acetate at 200g per ton (positive control; POSCON): T3, T4, T5 and T6-control diet supplemented with 2, 4, 6 and 8g/kg PPPM (PPPM2, PPPM4, PPPM6, PPPM8). The phytochemical, nutritional and antioxidant properties of the pomegranate peel powder were determined. Results showed that the South African-grown pomegranate peel (“Wonderful” variety) had rich protein and trace mineral contents. Higher (p < 0.05) antioxidant and hepatic anti-lipid peroxidative activities were recorded in the ethanol and acetone extracts than the water extract, whereas the three extracts had no toxic effects on liver and kidney cells (p > 0.05). The dietary effects of PPPM supplementation on growth performance, digestibility, carcass, and organ weight indices of Cobb 500 birds were determined. The POSCON diet enhanced (p < 0.05) feed conversion ratio (FCR) at week 3. The average final body weight and average daily weight gain were highest (p < 0.05) in birds fed PPPM2 and PPPM4 diets, whereas birds fed PPPM2 diet had enhanced (p < 0.05) FCR and protein efficiency ratio when compared with birds on POSCON. Thigh and breast weights were highest (p < 0.05) in birds on PPPM4 and PPPM8 diets, whereas birds fed PPPM4 diet had enhanced (p < 0.05) nutrient digestibility compared with those on POSCON. The antioxidant status and breast meat quality of Cobb 500 broiler birds fed diets supplemented with PPPM were determined. Meat from birds fed PPPM8 diet had the highest (p < 0.05) thawing loss, while cooking loss was lowest (p < 0.05) in the PPPM2 group. The highest (p < 0.05) ability to scavenge ABTS [(2, 2-azinobis (3ethylbenzothiazoline-6 sulfonic acid))] radical cation (ABTS+) was recorded in the PPPM2 and PPPM4 meat while PPPM8 meat had increased (p < 0.05) catalase activity. The fatty acid composition, oxidative status, and drip loss in breast meat of Cobb 500 broiler birds fed graded levels of PPPM was determined. Meat from birds fed PPPM4 diet had the lowest (p < 0.05) margaric (C17:0) and arachidic (C20:0) acids, while meat from birds fed PPPM8 diet had higher (p < 0.05) levels of eicosadenoic (C20:2, n-6) and arachidonic (AA, 20:4) acids. The POSCON had higher (p < 0.05) ability to reduce TBARS levels in meat on day-1 and day-16 of storage than the NEGCON and PPPM diets, whereas TBARS levels were lowest (p < 0.05) in PPPM6 meat on day-16. The gut pH, histology, haematology, serum-biochemical indices, and bone quality parameters of Cobb 500 broiler birds fed diets supplemented with PPPM was determined. Birds fed POSCON, PPM2 and PPPM4 diets had the lowest (p < 0.05) pH in the duodenum, jejunum, and caecum, whereas duodenal pH values were lowest (p < 0.05) in birds fed PPPM2 and PPPM4 diets compared with birds on NEGCON. Birds fed PPPM4 diet had the highest (p < 0.01) duodenal, jejunal and ileal villi height (VH), and the highest (p < 0.01) VH to crypt depth (CD) ratio in the duodenum, jejunum, and ileum. The lowest (p < 0.05) CD in the duodenum, jejunum and ileum was also recorded in birds fed PPPM4 diet. Birds fed PPPM8 diet had higher (p < 0.05) values for white blood cell count, red blood cell count, haemoglobin concentration and packed cell volume, whereas the lowest (p < 0.05) concentration of serum aspartate transaminase was recorded in birds fed PPPM4 diet. Birds on PPM4 diet had longer (p < 0.05) bones. Bone weight and bone breaking strength were highest (p < 0.05) in birds fed PPPM8 diet. Tibia zinc and iron concentrations increased as the inclusion levels of pomegranate peel powder meal increased. It was concluded that broiler birds require 4 g/kg pomegranate peel powder for enhanced growth performance, nutrient digestibility, gut histology, quality, and antioxidant enzyme activity of meat, whereas 8 g/kg pomegranate peel powder meal supplementation is required for enhanced heamato-biochemical indices, bone quality, fatty acid composition and lipid peroxidative parameters in broiler birds. , Thesis (PhD) -- Faculty of Science and Agriculture, 2022
- Full Text:
- Date Issued: 2022-04
- Authors: Akuru, Eunice Amaka https://orcid.org/0000-0002-3093-0247
- Date: 2022-04
- Subjects: Broilers (Chickens) , Meat -- Quality
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10353/23611 , vital:58218
- Description: The objective of the current study was to investigate the overall response of broiler birds to varying dietary levels of pomegranate (Punica granatum L) peel powder meal (PPPM). A total of 432-day-old Cobb 500 broiler chicks were randomly divided into six experimental groups of four replications with 18 birds per replicate in a completely randomized design (CRD). The birds were fed isonitrogenous and isocaloric experimental diets designated as: T1-control diet with 0percent additives (negative control; NEGCON); T2- control diet supplemented with α-tocopherol acetate at 200g per ton (positive control; POSCON): T3, T4, T5 and T6-control diet supplemented with 2, 4, 6 and 8g/kg PPPM (PPPM2, PPPM4, PPPM6, PPPM8). The phytochemical, nutritional and antioxidant properties of the pomegranate peel powder were determined. Results showed that the South African-grown pomegranate peel (“Wonderful” variety) had rich protein and trace mineral contents. Higher (p < 0.05) antioxidant and hepatic anti-lipid peroxidative activities were recorded in the ethanol and acetone extracts than the water extract, whereas the three extracts had no toxic effects on liver and kidney cells (p > 0.05). The dietary effects of PPPM supplementation on growth performance, digestibility, carcass, and organ weight indices of Cobb 500 birds were determined. The POSCON diet enhanced (p < 0.05) feed conversion ratio (FCR) at week 3. The average final body weight and average daily weight gain were highest (p < 0.05) in birds fed PPPM2 and PPPM4 diets, whereas birds fed PPPM2 diet had enhanced (p < 0.05) FCR and protein efficiency ratio when compared with birds on POSCON. Thigh and breast weights were highest (p < 0.05) in birds on PPPM4 and PPPM8 diets, whereas birds fed PPPM4 diet had enhanced (p < 0.05) nutrient digestibility compared with those on POSCON. The antioxidant status and breast meat quality of Cobb 500 broiler birds fed diets supplemented with PPPM were determined. Meat from birds fed PPPM8 diet had the highest (p < 0.05) thawing loss, while cooking loss was lowest (p < 0.05) in the PPPM2 group. The highest (p < 0.05) ability to scavenge ABTS [(2, 2-azinobis (3ethylbenzothiazoline-6 sulfonic acid))] radical cation (ABTS+) was recorded in the PPPM2 and PPPM4 meat while PPPM8 meat had increased (p < 0.05) catalase activity. The fatty acid composition, oxidative status, and drip loss in breast meat of Cobb 500 broiler birds fed graded levels of PPPM was determined. Meat from birds fed PPPM4 diet had the lowest (p < 0.05) margaric (C17:0) and arachidic (C20:0) acids, while meat from birds fed PPPM8 diet had higher (p < 0.05) levels of eicosadenoic (C20:2, n-6) and arachidonic (AA, 20:4) acids. The POSCON had higher (p < 0.05) ability to reduce TBARS levels in meat on day-1 and day-16 of storage than the NEGCON and PPPM diets, whereas TBARS levels were lowest (p < 0.05) in PPPM6 meat on day-16. The gut pH, histology, haematology, serum-biochemical indices, and bone quality parameters of Cobb 500 broiler birds fed diets supplemented with PPPM was determined. Birds fed POSCON, PPM2 and PPPM4 diets had the lowest (p < 0.05) pH in the duodenum, jejunum, and caecum, whereas duodenal pH values were lowest (p < 0.05) in birds fed PPPM2 and PPPM4 diets compared with birds on NEGCON. Birds fed PPPM4 diet had the highest (p < 0.01) duodenal, jejunal and ileal villi height (VH), and the highest (p < 0.01) VH to crypt depth (CD) ratio in the duodenum, jejunum, and ileum. The lowest (p < 0.05) CD in the duodenum, jejunum and ileum was also recorded in birds fed PPPM4 diet. Birds fed PPPM8 diet had higher (p < 0.05) values for white blood cell count, red blood cell count, haemoglobin concentration and packed cell volume, whereas the lowest (p < 0.05) concentration of serum aspartate transaminase was recorded in birds fed PPPM4 diet. Birds on PPM4 diet had longer (p < 0.05) bones. Bone weight and bone breaking strength were highest (p < 0.05) in birds fed PPPM8 diet. Tibia zinc and iron concentrations increased as the inclusion levels of pomegranate peel powder meal increased. It was concluded that broiler birds require 4 g/kg pomegranate peel powder for enhanced growth performance, nutrient digestibility, gut histology, quality, and antioxidant enzyme activity of meat, whereas 8 g/kg pomegranate peel powder meal supplementation is required for enhanced heamato-biochemical indices, bone quality, fatty acid composition and lipid peroxidative parameters in broiler birds. , Thesis (PhD) -- Faculty of Science and Agriculture, 2022
- Full Text:
- Date Issued: 2022-04