A research tool for analysing and monitoring the Extent to which Environmental issues are integrated into teachers’ lessons
- Authors: Nsubuga, Yvonne
- Date: 2011
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/386447 , vital:68142 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122246"
- Description: South Africa enjoys strong policy support for the integration of environmental issues into school curricula. However, much doubt exists over the extent to which this has been converted into appropriate classroom practice at the majority of under-resourced rural schools in the country. This article reports on a study which piloted a research tool which can be used to analyse teachers’ lessons, with the aim of gaining insight into the extent to which they integrate natural resource management issues. The research tool was based on Bernstein’s concept of classification and consisted of five indicators of natural resource management integration into Life Sciences lessons. The study contributes to the design of research tools that can be used to analyse and monitor the integration of environmental issues into teachers’ lessons. It also provides some insight into the environmental content of a sample of Grade 10 Life Sciences lessons at four rural underresourced schools in the Eastern Cape.
- Full Text:
- Date Issued: 2011
- Authors: Nsubuga, Yvonne
- Date: 2011
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/386447 , vital:68142 , xlink:href="https://www.ajol.info/index.php/sajee/article/view/122246"
- Description: South Africa enjoys strong policy support for the integration of environmental issues into school curricula. However, much doubt exists over the extent to which this has been converted into appropriate classroom practice at the majority of under-resourced rural schools in the country. This article reports on a study which piloted a research tool which can be used to analyse teachers’ lessons, with the aim of gaining insight into the extent to which they integrate natural resource management issues. The research tool was based on Bernstein’s concept of classification and consisted of five indicators of natural resource management integration into Life Sciences lessons. The study contributes to the design of research tools that can be used to analyse and monitor the integration of environmental issues into teachers’ lessons. It also provides some insight into the environmental content of a sample of Grade 10 Life Sciences lessons at four rural underresourced schools in the Eastern Cape.
- Full Text:
- Date Issued: 2011
Data quality issues in electronic health records for large-scale databases
- Authors: Saiod, Abdul Kader
- Date: 2019
- Subjects: Electronic Health Records , Electronic Health Records--organization & administration Database management
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/44940 , vital:38190
- Description: Data Quality (DQ) in Electronic Health Records (EHRs) is one of the core functions that play a decisive role to improve the healthcare service quality. The DQ issues in EHRs are a noticeable trend to improve the introduction of an adaptive framework for interoperability and standards in Large-Scale Databases (LSDB) management systems. Therefore, large data communications are challenging in the traditional approaches to satisfy the needs of the consumers, as data is often not capture directly into the Database Management Systems (DBMS) in a seasonably enough fashion to enable their subsequent uses. In addition, large data plays a vital role in containing plenty of treasures for all the fields in the DBMS. EHRs technology provides portfolio management systems that allow HealthCare Organisations (HCOs) to deliver a higher quality of care to their patients than that which is possible with paper-based records. EHRs are in high demand for HCOs to run their daily services as increasing numbers of huge datasets occur every day. Efficient EHR systems reduce the data redundancy as well as the system application failure and increase the possibility to draw all necessary reports. However, one of the main challenges in developing efficient EHR systems is the inherent difficulty to coherently manage data from diverse heterogeneous sources. It is practically challenging to integrate diverse data into a global schema, which satisfies the need of users. The efficient management of HER systems using an existing DBMS present challenges because of incompatibility and sometimes inconsistency of data structures. As a result, no common methodological approach is currently in existence to effectively solve every data integration problem. The challenges of the DQ issue raised the need to find an efficient way to integrate large EHRs from diverse heterogeneous sources. To handle and align a large dataset efficiently, the hybrid algorithm method with the logical combination of Fuzzy-Ontology along with a large-scale EHRs analysis platform has shown the results in term of improved accuracy. This study investigated and addressed the raised DQ issues to interventions to overcome these barriers and challenges, including the provision of EHRs as they pertain to DQ and has combined features to search, extract, filter, clean and integrate data to ensure that users can coherently create new consistent data sets. The study researched the design of a hybrid method based on Fuzzy-Ontology with performed mathematical simulations based on the Markov Chain Probability Model. The similarity measurement based on dynamic Hungarian algorithm was followed by the Design Science Research (DSR) methodology, which will increase the quality of service over HCOs in adaptive frameworks.
- Full Text:
- Date Issued: 2019
- Authors: Saiod, Abdul Kader
- Date: 2019
- Subjects: Electronic Health Records , Electronic Health Records--organization & administration Database management
- Language: English
- Type: Thesis , Doctoral , DPhil
- Identifier: http://hdl.handle.net/10948/44940 , vital:38190
- Description: Data Quality (DQ) in Electronic Health Records (EHRs) is one of the core functions that play a decisive role to improve the healthcare service quality. The DQ issues in EHRs are a noticeable trend to improve the introduction of an adaptive framework for interoperability and standards in Large-Scale Databases (LSDB) management systems. Therefore, large data communications are challenging in the traditional approaches to satisfy the needs of the consumers, as data is often not capture directly into the Database Management Systems (DBMS) in a seasonably enough fashion to enable their subsequent uses. In addition, large data plays a vital role in containing plenty of treasures for all the fields in the DBMS. EHRs technology provides portfolio management systems that allow HealthCare Organisations (HCOs) to deliver a higher quality of care to their patients than that which is possible with paper-based records. EHRs are in high demand for HCOs to run their daily services as increasing numbers of huge datasets occur every day. Efficient EHR systems reduce the data redundancy as well as the system application failure and increase the possibility to draw all necessary reports. However, one of the main challenges in developing efficient EHR systems is the inherent difficulty to coherently manage data from diverse heterogeneous sources. It is practically challenging to integrate diverse data into a global schema, which satisfies the need of users. The efficient management of HER systems using an existing DBMS present challenges because of incompatibility and sometimes inconsistency of data structures. As a result, no common methodological approach is currently in existence to effectively solve every data integration problem. The challenges of the DQ issue raised the need to find an efficient way to integrate large EHRs from diverse heterogeneous sources. To handle and align a large dataset efficiently, the hybrid algorithm method with the logical combination of Fuzzy-Ontology along with a large-scale EHRs analysis platform has shown the results in term of improved accuracy. This study investigated and addressed the raised DQ issues to interventions to overcome these barriers and challenges, including the provision of EHRs as they pertain to DQ and has combined features to search, extract, filter, clean and integrate data to ensure that users can coherently create new consistent data sets. The study researched the design of a hybrid method based on Fuzzy-Ontology with performed mathematical simulations based on the Markov Chain Probability Model. The similarity measurement based on dynamic Hungarian algorithm was followed by the Design Science Research (DSR) methodology, which will increase the quality of service over HCOs in adaptive frameworks.
- Full Text:
- Date Issued: 2019
Biomechanical Analysis of Movement: HUS 514
- Xoxo, T, Lyoko, P, Travill, A
- Authors: Xoxo, T , Lyoko, P , Travill, A
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:18249 , http://hdl.handle.net/10353/d1011243
- Description: Biomechanical Analysis of Movement: HUS 514, degree examination June 2011.
- Full Text: false
- Date Issued: 2011-06
- Authors: Xoxo, T , Lyoko, P , Travill, A
- Date: 2011-06
- Language: English
- Type: Examination paper
- Identifier: vital:18249 , http://hdl.handle.net/10353/d1011243
- Description: Biomechanical Analysis of Movement: HUS 514, degree examination June 2011.
- Full Text: false
- Date Issued: 2011-06
Epidemic transmission of intestinal schistosomiasis in the seasonal part of the Okavango Delta, Botswana:
- Appleton, C C, Ellery, William F N, Byskov, Jens, Mogkweetsinyana, S S
- Authors: Appleton, C C , Ellery, William F N , Byskov, Jens , Mogkweetsinyana, S S
- Date: 2013
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/144364 , vital:38339 , DOI: 10.1179/136485908X311867
- Description: A well documented epidemic of human intestinal schistosomiasis caused by Schistosoma mansoni occurred at Maun in the seasonal part of the Okavango Delta, Botswana, building from very few cases in the 1950s and early 1960s to a peak prevalence of greater than80% in the 1980s. A retrospective analysis was performed on all available records of the prevalence of S. mansoni in the Maun area and the corresponding flow records of the Thamalakane River. These revealed a statistically significant correlation between prevalence and flow, but only when a lag period was introduced. The correlation was greatest with a lag period of 5–6 years between the rise and fall of discharge and the rise and fall of transmission. Since the hydrological events in the delta follow a cyclical pattern, another epidemic around 2020 appears likely.
- Full Text:
- Date Issued: 2013
- Authors: Appleton, C C , Ellery, William F N , Byskov, Jens , Mogkweetsinyana, S S
- Date: 2013
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/144364 , vital:38339 , DOI: 10.1179/136485908X311867
- Description: A well documented epidemic of human intestinal schistosomiasis caused by Schistosoma mansoni occurred at Maun in the seasonal part of the Okavango Delta, Botswana, building from very few cases in the 1950s and early 1960s to a peak prevalence of greater than80% in the 1980s. A retrospective analysis was performed on all available records of the prevalence of S. mansoni in the Maun area and the corresponding flow records of the Thamalakane River. These revealed a statistically significant correlation between prevalence and flow, but only when a lag period was introduced. The correlation was greatest with a lag period of 5–6 years between the rise and fall of discharge and the rise and fall of transmission. Since the hydrological events in the delta follow a cyclical pattern, another epidemic around 2020 appears likely.
- Full Text:
- Date Issued: 2013
Unitarity constraints on the ratio of shear viscosity to entropy density in higher derivative gravity
- Authors: Brustein, R , Medved, A J M
- Date: 2011
- Language: English
- Type: text , Article
- Identifier: vital:6815 , http://hdl.handle.net/10962/d1004325
- Description: We discuss corrections to the ratio of shear viscosity to entropy density η/s in higher-derivative gravity theories. Generically, these theories contain ghost modes with Planck-scale masses. Motivated by general considerations about unitarity, we propose new boundary conditions for the equations of motion of the graviton perturbations that force the amplitude of the ghosts modes to vanish. We analyze explicitly four-derivative perturbative corrections to Einstein gravity which generically lead to four-derivative equations of motion, compare our choice of boundary conditions to previous proposals and show that, with our new prescription, the ratio η/s remains at the Einstein-gravity value of 1/4π to leading order in the corrections. It is argued that, when the new boundary conditions are imposed on six and higher-derivative equations of motion, η/s can only increase from the Einstein-gravity value. We also recall some general arguments that support the validity of our results to all orders in the strength of the corrections to Einstein gravity. We then discuss the particular case of Gauss-Bonnet gravity, for which the equations of motion are only of two-derivative order and the value of η/s can decrease below 1/4π when treated in a nonperturbative way. Our findings provide further evidence for the validity of the KSS bound for theories that can be viewed as perturbative corrections to Einstein gravity.
- Full Text:
- Date Issued: 2011
- Authors: Brustein, R , Medved, A J M
- Date: 2011
- Language: English
- Type: text , Article
- Identifier: vital:6815 , http://hdl.handle.net/10962/d1004325
- Description: We discuss corrections to the ratio of shear viscosity to entropy density η/s in higher-derivative gravity theories. Generically, these theories contain ghost modes with Planck-scale masses. Motivated by general considerations about unitarity, we propose new boundary conditions for the equations of motion of the graviton perturbations that force the amplitude of the ghosts modes to vanish. We analyze explicitly four-derivative perturbative corrections to Einstein gravity which generically lead to four-derivative equations of motion, compare our choice of boundary conditions to previous proposals and show that, with our new prescription, the ratio η/s remains at the Einstein-gravity value of 1/4π to leading order in the corrections. It is argued that, when the new boundary conditions are imposed on six and higher-derivative equations of motion, η/s can only increase from the Einstein-gravity value. We also recall some general arguments that support the validity of our results to all orders in the strength of the corrections to Einstein gravity. We then discuss the particular case of Gauss-Bonnet gravity, for which the equations of motion are only of two-derivative order and the value of η/s can decrease below 1/4π when treated in a nonperturbative way. Our findings provide further evidence for the validity of the KSS bound for theories that can be viewed as perturbative corrections to Einstein gravity.
- Full Text:
- Date Issued: 2011
Problems experienced by project managers on housing projects
- Mtshekexe, Ntombesibini Octavia
- Authors: Mtshekexe, Ntombesibini Octavia
- Date: 2014
- Subjects: Project management , Housing rehabilitation , Public housing -- South Africa , Building -- Superintendence
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:9675 , http://hdl.handle.net/10948/d1020930
- Description: Housing projects are amongst the South African (SA) Government’s major focus points with reference to budgeting for its financial years. The delivery of these housing projects is taking place at a slower rate than anticipated due to the problems experienced in the processes involved in their management. The project management shortcomings are a major setback with reference to the delivery of houses to the communities. It is, however, stated by the Constitution of the Republic of South Africa (RSA) that every South African citizen has a right to housing and that the Local Government, as the closest entity to communities, must do whatever it possibly can to ensure timeous service delivery to its communities. The objective of this research is to ascertain the nature and extent of project management problems experienced by municipal project managers, the impact thereof and potential solutions to the identified problems. The study is intended to advise on possible ways to address project management problems arising during the implementation of housing projects in the Nelson Mandela Bay Municipality (NMBM) through investigation and analysis of information gathered in both theory and practice. Project management is a process of controlling the achievement of project objectives through the application of knowledge, skills, tools and techniques. For a housing project the main objective is to deliver safe, quality houses on time and within budget. Problems which hinder the delivery of housing projects relate to cost, time and the quality of housing projects delivered. The fact that these key project objectives are not met needs to be addressed urgently in order to improve the housing delivery. The literature reviewed and the feedback from the surveys; indicate that these problems have a vast impact on housing projects. The survey also reveals that it is not only housing Project Managers (PMs) that are unable to perform well, but also other parties involved in the project management of housing projects and which play a great role in project management failures of housing projects. Some of these parties are consultants and contractors. The lack of performance by project managers affects the delivery of houses negatively in the NMBM.
- Full Text:
- Date Issued: 2014
- Authors: Mtshekexe, Ntombesibini Octavia
- Date: 2014
- Subjects: Project management , Housing rehabilitation , Public housing -- South Africa , Building -- Superintendence
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:9675 , http://hdl.handle.net/10948/d1020930
- Description: Housing projects are amongst the South African (SA) Government’s major focus points with reference to budgeting for its financial years. The delivery of these housing projects is taking place at a slower rate than anticipated due to the problems experienced in the processes involved in their management. The project management shortcomings are a major setback with reference to the delivery of houses to the communities. It is, however, stated by the Constitution of the Republic of South Africa (RSA) that every South African citizen has a right to housing and that the Local Government, as the closest entity to communities, must do whatever it possibly can to ensure timeous service delivery to its communities. The objective of this research is to ascertain the nature and extent of project management problems experienced by municipal project managers, the impact thereof and potential solutions to the identified problems. The study is intended to advise on possible ways to address project management problems arising during the implementation of housing projects in the Nelson Mandela Bay Municipality (NMBM) through investigation and analysis of information gathered in both theory and practice. Project management is a process of controlling the achievement of project objectives through the application of knowledge, skills, tools and techniques. For a housing project the main objective is to deliver safe, quality houses on time and within budget. Problems which hinder the delivery of housing projects relate to cost, time and the quality of housing projects delivered. The fact that these key project objectives are not met needs to be addressed urgently in order to improve the housing delivery. The literature reviewed and the feedback from the surveys; indicate that these problems have a vast impact on housing projects. The survey also reveals that it is not only housing Project Managers (PMs) that are unable to perform well, but also other parties involved in the project management of housing projects and which play a great role in project management failures of housing projects. Some of these parties are consultants and contractors. The lack of performance by project managers affects the delivery of houses negatively in the NMBM.
- Full Text:
- Date Issued: 2014
Examining the nature of entrepreneurship within the towns and rural areas of Sakhisizwe Local Municipality, Eastern Cape
- Authors: Maliwa, Noluvuyo
- Date: 2022-11
- Subjects: Entrepreneurship , Developing countries--Economic conditions , Small business
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27555 , vital:69315
- Description: Entrepreneurship plays an important role in societies around the world because it supports economic growth and creates job opportunities. This study investigated the nature of entrepreneurship in three distinct parts of Sakhisizwe Local Municipality, including a town within Sakhisizwe’s former homeland area, rural communities within its former homeland area, and a town within an area characterised by large-scale commercial farms. The study sought to establish the share of adults in the different parts of the municipality involved in entrepreneurship, to identify factors that contribute to the decision to become an entrepreneur, and to examine strategies pursued by, and challenges experienced, different types of entrepreneurs. The study involved a random sample of 362 respondents and both quantitative and qualitative data analysis. Among the main findings is that the proportion of adults involved in enterprise in Sakhisizwe is higher than found by other studies for South Africa as a whole, but is especially high for those living in the town in the former homeland area. While those residing in rural communities also engage in enterprise, they are generally compelled to practice their enterprises in town, thus have the disadvantage of needing frequent transport. While residing in the town in the commercial farming area is not disadvantageous in the same way, the challenge is that the town itself is able to support relatively few entrepreneurs due to fewer people coming to town for their shopping. , Thesis (MSci) -- Faculty of Science and Agricultures, 2022
- Full Text:
- Date Issued: 2022-11
- Authors: Maliwa, Noluvuyo
- Date: 2022-11
- Subjects: Entrepreneurship , Developing countries--Economic conditions , Small business
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10353/27555 , vital:69315
- Description: Entrepreneurship plays an important role in societies around the world because it supports economic growth and creates job opportunities. This study investigated the nature of entrepreneurship in three distinct parts of Sakhisizwe Local Municipality, including a town within Sakhisizwe’s former homeland area, rural communities within its former homeland area, and a town within an area characterised by large-scale commercial farms. The study sought to establish the share of adults in the different parts of the municipality involved in entrepreneurship, to identify factors that contribute to the decision to become an entrepreneur, and to examine strategies pursued by, and challenges experienced, different types of entrepreneurs. The study involved a random sample of 362 respondents and both quantitative and qualitative data analysis. Among the main findings is that the proportion of adults involved in enterprise in Sakhisizwe is higher than found by other studies for South Africa as a whole, but is especially high for those living in the town in the former homeland area. While those residing in rural communities also engage in enterprise, they are generally compelled to practice their enterprises in town, thus have the disadvantage of needing frequent transport. While residing in the town in the commercial farming area is not disadvantageous in the same way, the challenge is that the town itself is able to support relatively few entrepreneurs due to fewer people coming to town for their shopping. , Thesis (MSci) -- Faculty of Science and Agricultures, 2022
- Full Text:
- Date Issued: 2022-11
How to spread it: Saleem Badat
- Authors: Badat, Saleem
- Date: 2013-08-04
- Language: English
- Type: Text
- Identifier: vital:7903 , http://hdl.handle.net/10962/d1016453
- Full Text:
- Date Issued: 2013-08-04
- Authors: Badat, Saleem
- Date: 2013-08-04
- Language: English
- Type: Text
- Identifier: vital:7903 , http://hdl.handle.net/10962/d1016453
- Full Text:
- Date Issued: 2013-08-04
Uptake of liposomes into bacterial cells
- Authors: Oidu, Benjamin
- Date: 2013
- Subjects: Liposomes , Drug carriers (Pharmacy)
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10165 , http://hdl.handle.net/10948/d1021010
- Description: Liposomes are small phospholipid vesicles that have been widely investigated as drug carriers for the delivery of therapeutic agents. A variety of liposome formulations are presently under clinical trial exploration, while others have already been approved for clinical use. The aim of this study was to optimize liposome uptake into bacterial cells. Both gram-positive and gram-negative bacteria were used in the study as well as Candida albicans.Response surface methodology (RSM) using a central composite design (CCD) model was used to optimize liposomal formulations of carboxyfluorescien (CF) for each of the three microbes, and also the three microbes in combination namely; Staphylococcus aureus (Sa), Escherichia coli (Ec) and Candida albicans (Ca). Percentage of CF encapsulated and CF increase in Uptake were investigated with respect to two independent variables that were, cholesterol (CHOL) and stearylamine (SA) content. Design Expert 8 was used for the purpose of finding the combination of independent variables that would yield an optimal formulation for each microbe and the three microbes in combination. The model selected by the software managed to reasonably correlate the predicted models to the experimental data. Encapsulation of carboxyfluorescien (CF) into a liposome formulation enhanced its uptake by Staphylococcus aureus and Escherichia coli as well as Candida albicans. This was evident in the increase in CF uptake when the uptake rate of free CF was compared with that of liposomal CF.
- Full Text:
- Date Issued: 2013
- Authors: Oidu, Benjamin
- Date: 2013
- Subjects: Liposomes , Drug carriers (Pharmacy)
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:10165 , http://hdl.handle.net/10948/d1021010
- Description: Liposomes are small phospholipid vesicles that have been widely investigated as drug carriers for the delivery of therapeutic agents. A variety of liposome formulations are presently under clinical trial exploration, while others have already been approved for clinical use. The aim of this study was to optimize liposome uptake into bacterial cells. Both gram-positive and gram-negative bacteria were used in the study as well as Candida albicans.Response surface methodology (RSM) using a central composite design (CCD) model was used to optimize liposomal formulations of carboxyfluorescien (CF) for each of the three microbes, and also the three microbes in combination namely; Staphylococcus aureus (Sa), Escherichia coli (Ec) and Candida albicans (Ca). Percentage of CF encapsulated and CF increase in Uptake were investigated with respect to two independent variables that were, cholesterol (CHOL) and stearylamine (SA) content. Design Expert 8 was used for the purpose of finding the combination of independent variables that would yield an optimal formulation for each microbe and the three microbes in combination. The model selected by the software managed to reasonably correlate the predicted models to the experimental data. Encapsulation of carboxyfluorescien (CF) into a liposome formulation enhanced its uptake by Staphylococcus aureus and Escherichia coli as well as Candida albicans. This was evident in the increase in CF uptake when the uptake rate of free CF was compared with that of liposomal CF.
- Full Text:
- Date Issued: 2013
The photophysical studies of Pluronic F127/P123 micelle mixture system loaded with metal free and Zn 5, 10, 15, 20-tetrakis [4-(benzyloxy) phenyl] porphyrins
- Managa, Muthumuni, Ngoy, Bokolombe P, Nyokong, Tebello
- Authors: Managa, Muthumuni , Ngoy, Bokolombe P , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188932 , vital:44799 , xlink:href="https://doi.org/10.1016/j.jphotochem.2017.02.018"
- Description: Binary mixtures of Pluronics are studied as drug nanocarriers in this work. H2 and Zn 5,10,15,20-tetrakis[4-(benzyloxy) phenyl] porphyrin were encapsulated onto binary micelle mixture of Pluronic F127/P123. The fluorescence and singlet oxygen generating behaviour of the porphyrins were investigated following incorporation. The fluorescence quantum yield for H2TBnOPP (ΦF = 0.034) was higher than that of ZnTBnOPP (ΦF = 0.023) and decreased when ZnTBnOPP or H2TBnOPP when in the presence of Pluronic F127/P123 binary mixtures. The kq values were 2.8 × 108 and 3.7 × 108 M−1 s−1, for H2TBnOPP + Pluronic F127/P123 and ZnTBnOPP + Pluronic F127/P123 in water, respectively. The binding constants (Kb) were 1.58 × 105 M−1 and 1.02 × 105 M−1 for ZnTBnOPP + Pluronic F127/P123 and H2TBnOPP + Pluronic F127/P123, respectively.
- Full Text:
- Date Issued: 2017
- Authors: Managa, Muthumuni , Ngoy, Bokolombe P , Nyokong, Tebello
- Date: 2017
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/188932 , vital:44799 , xlink:href="https://doi.org/10.1016/j.jphotochem.2017.02.018"
- Description: Binary mixtures of Pluronics are studied as drug nanocarriers in this work. H2 and Zn 5,10,15,20-tetrakis[4-(benzyloxy) phenyl] porphyrin were encapsulated onto binary micelle mixture of Pluronic F127/P123. The fluorescence and singlet oxygen generating behaviour of the porphyrins were investigated following incorporation. The fluorescence quantum yield for H2TBnOPP (ΦF = 0.034) was higher than that of ZnTBnOPP (ΦF = 0.023) and decreased when ZnTBnOPP or H2TBnOPP when in the presence of Pluronic F127/P123 binary mixtures. The kq values were 2.8 × 108 and 3.7 × 108 M−1 s−1, for H2TBnOPP + Pluronic F127/P123 and ZnTBnOPP + Pluronic F127/P123 in water, respectively. The binding constants (Kb) were 1.58 × 105 M−1 and 1.02 × 105 M−1 for ZnTBnOPP + Pluronic F127/P123 and H2TBnOPP + Pluronic F127/P123, respectively.
- Full Text:
- Date Issued: 2017
NUM Memorandum - State policy on the crisis in the Gold mining industry
- NUM
- Authors: NUM
- Date: June 1992
- Subjects: NUM
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/149541 , vital:38862
- Description: The National Union of Mineworkers has asked for a meeting with the Minister to highlight the severe social and economic effects that are caused by the low rand gold price and the consequent rationalisation measures that are being implemented by the gold mines. The severity of the crisis is well illustrated by the case of the Harmony Gold Mine in the Orange Free State. This is the largest of the so-called "marginal" gold mines and last week it retrenched over 6 000 workers. The gold mines have cut back over 130 000 jobs over the last five years. The job cuts have speeded up again in 1992 as the gold price has continued at low levels. The NUM expressed its deep concern at this contraction in the gold industry most strongly at the Summit on the Future of the Mining Industry in June 1992. This meeting was attended by mining houses, the trade unions and several state departments. The NUM made a plea for a national plan and a national policy to regulate and manage the process of down-scaling. Despite the formation of a Summit Steering Committee to consider this and other proposals, and a whole series of working-group meetings involving all parties, nothing practical has come out of the process to address the issue of down-scaling.
- Full Text:
- Date Issued: June 1992
- Authors: NUM
- Date: June 1992
- Subjects: NUM
- Language: English
- Type: text
- Identifier: http://hdl.handle.net/10962/149541 , vital:38862
- Description: The National Union of Mineworkers has asked for a meeting with the Minister to highlight the severe social and economic effects that are caused by the low rand gold price and the consequent rationalisation measures that are being implemented by the gold mines. The severity of the crisis is well illustrated by the case of the Harmony Gold Mine in the Orange Free State. This is the largest of the so-called "marginal" gold mines and last week it retrenched over 6 000 workers. The gold mines have cut back over 130 000 jobs over the last five years. The job cuts have speeded up again in 1992 as the gold price has continued at low levels. The NUM expressed its deep concern at this contraction in the gold industry most strongly at the Summit on the Future of the Mining Industry in June 1992. This meeting was attended by mining houses, the trade unions and several state departments. The NUM made a plea for a national plan and a national policy to regulate and manage the process of down-scaling. Despite the formation of a Summit Steering Committee to consider this and other proposals, and a whole series of working-group meetings involving all parties, nothing practical has come out of the process to address the issue of down-scaling.
- Full Text:
- Date Issued: June 1992
Detecting plant species in the field with deep learning and drone technology:
- James, Katherine, Bradshaw, Karen
- Authors: James, Katherine , Bradshaw, Karen
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/160445 , vital:40446 , https://0-doi.org.wam.seals.ac.za/10.1111/2041-210X.13473
- Description: Aerial drones are providing a new source of high‐resolution imagery for mapping of plant species of interest, amongst other applications. On‐board detection algorithms could open the door to allow for applications in which drones can intelligently interact with their environment. However, the majority of plant detection studies have focused on detection in post‐flight processed orthomosaics. Greater research into developing detection algorithms robust to real‐world variations in environmental conditions is necessary, such that they are suitable for deployment in the field under variable conditions. We outline the steps necessary to develop such a system, show by example how real‐world considerations can be addressed during model training and briefly illustrate the performance of our best performing model in the field when integrated with an aerial drone.
- Full Text:
- Date Issued: 2020
- Authors: James, Katherine , Bradshaw, Karen
- Date: 2020
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/160445 , vital:40446 , https://0-doi.org.wam.seals.ac.za/10.1111/2041-210X.13473
- Description: Aerial drones are providing a new source of high‐resolution imagery for mapping of plant species of interest, amongst other applications. On‐board detection algorithms could open the door to allow for applications in which drones can intelligently interact with their environment. However, the majority of plant detection studies have focused on detection in post‐flight processed orthomosaics. Greater research into developing detection algorithms robust to real‐world variations in environmental conditions is necessary, such that they are suitable for deployment in the field under variable conditions. We outline the steps necessary to develop such a system, show by example how real‐world considerations can be addressed during model training and briefly illustrate the performance of our best performing model in the field when integrated with an aerial drone.
- Full Text:
- Date Issued: 2020
A short composition portfolio
- Buitendag, Kingsley Alexander
- Authors: Buitendag, Kingsley Alexander
- Date: 2011
- Subjects: Music -- South Africa Composition (Music)
- Language: English
- Type: text , Thesis , Masters , MMus
- Identifier: vital:2632 , http://hdl.handle.net/10962/d1002297
- Full Text:
- Date Issued: 2011
- Authors: Buitendag, Kingsley Alexander
- Date: 2011
- Subjects: Music -- South Africa Composition (Music)
- Language: English
- Type: text , Thesis , Masters , MMus
- Identifier: vital:2632 , http://hdl.handle.net/10962/d1002297
- Full Text:
- Date Issued: 2011
Effect of adding a probiotic to an aquaponic system on plant and fish growth, water quality, and microbial diversity
- Authors: Kasozi, Nasser
- Date: 2022-04-08
- Subjects: To be added
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/294596 , vital:57236
- Description: Thesis embargoed. Release date April 2023. , Thesis (PhD) -- Faculty of Science, Ichthyology and Fisheries Science, 2022
- Full Text:
- Date Issued: 2022-04-08
- Authors: Kasozi, Nasser
- Date: 2022-04-08
- Subjects: To be added
- Language: English
- Type: thesis , text , Doctoral , PhD
- Identifier: http://hdl.handle.net/10962/294596 , vital:57236
- Description: Thesis embargoed. Release date April 2023. , Thesis (PhD) -- Faculty of Science, Ichthyology and Fisheries Science, 2022
- Full Text:
- Date Issued: 2022-04-08
Polyunsaturated fatty acid metabolism and effects on colon cancer cell biology in vitro.
- Authors: Bulcao, Candice
- Date: 2013
- Subjects: Unsaturated fatty acids , Unsaturated fatty acids in human nutrition , Colon (Anatomy)-- Cancer , Cancer -- Nutritional aspects
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4137 , http://hdl.handle.net/10962/d1016128
- Description: Colon cancer is a leading cause of cancer related deaths worldwide. Lifestyle factors such as diet and exercise have been implicated as important agents in colon cancer development and progression. Epidemiological, in vivo and in vitro studies have found that n-3 polyunsaturated fatty acids (PUFAs) reduce colon carcinoma. The role of n-6 PUFAs remains a controversial topic, with studies indicating both promoting and preventing capabilities published. In order to better understand the effects of PUFAs on colon carcinoma, it is important to have an understanding of how they will be broken down in the body. During this study, in silico metabolism of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (AA) predicted the formation of hydroxy-, di-hydroxy- and epoxy-FAs. A gas chromatography-mass spectrometry method was developed and validated for the detection of these PUFAs and their cytochrome P450 (CYP) metabolites. A human liver microsomal system for the in vitro metabolism of EPA, DHA and AA was optimised in terms of microsomal and PUFA concentration. The system resulted in the metabolism of the positive control, lauric acid, to 12-hydroxy-lauric acid but was unable to metabolise the PUFAs of interest. EPA, DHA and AA reduced cell viability in the colon carcinoma cell lines SW480 and SW620 in the micromolar concentration range (25 – 200 μM). The CYP epoxidation metabolite of EPA, 17, 18-epoxyeicosatetraenoic acid (17, 18-EpETE) resulted in a significant reduction in SW480 cell viability relative to the parent compound at lower concentrations (25 and 50 μM). Annexin V apoptosis analysis revealed that EPA and 17, 18- EpETE did not result in apoptosis in SW480 cells at a concentration of 25 μM and over an incubation period of 24 hours. A significant reduction in reactive oxygen species production was seen in SW480 cells after incubation with 25 μM 17, 18-EpETE for 24 hours. EPA and 17, 18-EpETE were implicated in the reduction of colon cancer metastasis since they were able to reduce SW480 migration and anchorage independent cell growth. These results indicate that the dietary intake of EPA, DHA and AA may be beneficial to one’s health due to the negative effects that these PUFAs had on colon carcinoma. Future studies are needed to confirm these benefits and compare the effects of the PUFAs to their CYP-metabolites.
- Full Text:
- Date Issued: 2013
- Authors: Bulcao, Candice
- Date: 2013
- Subjects: Unsaturated fatty acids , Unsaturated fatty acids in human nutrition , Colon (Anatomy)-- Cancer , Cancer -- Nutritional aspects
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4137 , http://hdl.handle.net/10962/d1016128
- Description: Colon cancer is a leading cause of cancer related deaths worldwide. Lifestyle factors such as diet and exercise have been implicated as important agents in colon cancer development and progression. Epidemiological, in vivo and in vitro studies have found that n-3 polyunsaturated fatty acids (PUFAs) reduce colon carcinoma. The role of n-6 PUFAs remains a controversial topic, with studies indicating both promoting and preventing capabilities published. In order to better understand the effects of PUFAs on colon carcinoma, it is important to have an understanding of how they will be broken down in the body. During this study, in silico metabolism of eicosapentaenoic acid (EPA), docosahexaenoic acid (DHA) and arachidonic acid (AA) predicted the formation of hydroxy-, di-hydroxy- and epoxy-FAs. A gas chromatography-mass spectrometry method was developed and validated for the detection of these PUFAs and their cytochrome P450 (CYP) metabolites. A human liver microsomal system for the in vitro metabolism of EPA, DHA and AA was optimised in terms of microsomal and PUFA concentration. The system resulted in the metabolism of the positive control, lauric acid, to 12-hydroxy-lauric acid but was unable to metabolise the PUFAs of interest. EPA, DHA and AA reduced cell viability in the colon carcinoma cell lines SW480 and SW620 in the micromolar concentration range (25 – 200 μM). The CYP epoxidation metabolite of EPA, 17, 18-epoxyeicosatetraenoic acid (17, 18-EpETE) resulted in a significant reduction in SW480 cell viability relative to the parent compound at lower concentrations (25 and 50 μM). Annexin V apoptosis analysis revealed that EPA and 17, 18- EpETE did not result in apoptosis in SW480 cells at a concentration of 25 μM and over an incubation period of 24 hours. A significant reduction in reactive oxygen species production was seen in SW480 cells after incubation with 25 μM 17, 18-EpETE for 24 hours. EPA and 17, 18-EpETE were implicated in the reduction of colon cancer metastasis since they were able to reduce SW480 migration and anchorage independent cell growth. These results indicate that the dietary intake of EPA, DHA and AA may be beneficial to one’s health due to the negative effects that these PUFAs had on colon carcinoma. Future studies are needed to confirm these benefits and compare the effects of the PUFAs to their CYP-metabolites.
- Full Text:
- Date Issued: 2013
A consideration of the relations between Church and industry
- Authors: Hulley, L D
- Date: 1968
- Subjects: Industries -- Religious aspects , Church and industry , Christian life
- Language: English
- Type: Thesis , Bachelor , BDiv
- Identifier: vital:1295 , http://hdl.handle.net/10962/d1015396
- Description: [From Chapter 1]. The first point I wish to make, in fact it can be considered the primary one in this essay for what is to follow is a response to it, is that theology must be responding theology. This is a theology which takes the world seriously and responds to it in a Christian way. This is the approach we find in the New Testament: particularly in the Epistles, concrete problems and behaviour in the lives of his converts to which St. Paul responded prompted the didactic sections of his epistles. J. G. Davies supports this view in Planning for Mission "There are ... two primary realities'' he says "with which the congregation must be concerned: The Gospel of God and the world to which it is sent. 'Authentic theology' emerges out of the dialogue between the Gospel and the world." This is what Tillich calls the method of correlation. First we make an analysis of our situation and then try to relate the Christian message to the problems within it. While this compels us to rethink and reformulate many traditional Christian views, nothing "can change the substance of ... the ... answer, because this is the logos of being, manifest in Jesus as the Christ." This does not say that "we have all the answers" (in fact it will become clear that we do not), but it does express our conviction that the Christian Gospel has to do with life in all its aspects.
- Full Text:
- Date Issued: 1968
- Authors: Hulley, L D
- Date: 1968
- Subjects: Industries -- Religious aspects , Church and industry , Christian life
- Language: English
- Type: Thesis , Bachelor , BDiv
- Identifier: vital:1295 , http://hdl.handle.net/10962/d1015396
- Description: [From Chapter 1]. The first point I wish to make, in fact it can be considered the primary one in this essay for what is to follow is a response to it, is that theology must be responding theology. This is a theology which takes the world seriously and responds to it in a Christian way. This is the approach we find in the New Testament: particularly in the Epistles, concrete problems and behaviour in the lives of his converts to which St. Paul responded prompted the didactic sections of his epistles. J. G. Davies supports this view in Planning for Mission "There are ... two primary realities'' he says "with which the congregation must be concerned: The Gospel of God and the world to which it is sent. 'Authentic theology' emerges out of the dialogue between the Gospel and the world." This is what Tillich calls the method of correlation. First we make an analysis of our situation and then try to relate the Christian message to the problems within it. While this compels us to rethink and reformulate many traditional Christian views, nothing "can change the substance of ... the ... answer, because this is the logos of being, manifest in Jesus as the Christ." This does not say that "we have all the answers" (in fact it will become clear that we do not), but it does express our conviction that the Christian Gospel has to do with life in all its aspects.
- Full Text:
- Date Issued: 1968
Applications of polymerized metal tetra-amino phthalocyanines towards hydrogen peroxide detection
- Mashazi, Philani N, Togo, Chumunorwa, Limson, Janice, Nyokong, Tebello
- Authors: Mashazi, Philani N , Togo, Chumunorwa , Limson, Janice , Nyokong, Tebello
- Date: 2010
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/261840 , vital:53451 , xlink:href="https://doi.org/10.1142/S1088424610001994"
- Description: This work reports the use of metallo tetra-amino phthalocyanines (MTAPc, M = Co and Mn) polymer thin films on gold and glassy carbon electrode surfaces for the detection and monitoring of hydrogen peroxide (H2O2). The polymer-modified electrodes were characterized using electrochemical and microscopic-based methods. Atomic force microscopy (AFM) was used to study the bare and polymer-modified ITO surfaces. The electrocatalytic reduction of H2O2 with glassy carbon polymer-modified electrodes gave higher current densities compared to their gold counterparts. The electroanalytical properties of H2O2 were obtained using a real-time calibration curve of the amperometric determination in pH 7.4 aqueous solution. The limits of detection (LoD) of the polymer-modified electrodes towards electroreduction of H2O2 were of the order of 10–7 M, with high sensitivity ranging from 6.0–15.4 mA.mM-1.cm-2.
- Full Text:
- Date Issued: 2010
- Authors: Mashazi, Philani N , Togo, Chumunorwa , Limson, Janice , Nyokong, Tebello
- Date: 2010
- Subjects: To be catalogued
- Language: English
- Type: text , article
- Identifier: http://hdl.handle.net/10962/261840 , vital:53451 , xlink:href="https://doi.org/10.1142/S1088424610001994"
- Description: This work reports the use of metallo tetra-amino phthalocyanines (MTAPc, M = Co and Mn) polymer thin films on gold and glassy carbon electrode surfaces for the detection and monitoring of hydrogen peroxide (H2O2). The polymer-modified electrodes were characterized using electrochemical and microscopic-based methods. Atomic force microscopy (AFM) was used to study the bare and polymer-modified ITO surfaces. The electrocatalytic reduction of H2O2 with glassy carbon polymer-modified electrodes gave higher current densities compared to their gold counterparts. The electroanalytical properties of H2O2 were obtained using a real-time calibration curve of the amperometric determination in pH 7.4 aqueous solution. The limits of detection (LoD) of the polymer-modified electrodes towards electroreduction of H2O2 were of the order of 10–7 M, with high sensitivity ranging from 6.0–15.4 mA.mM-1.cm-2.
- Full Text:
- Date Issued: 2010
Economic change in town and countryside in the former Transkei : land use, livelihoods and market linkages in Ngcobo, Eastern Cape, South Africa
- Authors: Nikelo, Nqaba Benedictor
- Date: 2018
- Subjects: Homelands (South Africa) Homelands (South Africa) -- Economic conditions
- Language: English
- Type: Thesis , Masters , Agricultural Economics
- Identifier: http://hdl.handle.net/10353/10768 , vital:35757
- Description: In 1913 in South Africa the natives of land act during apartheid resulted to the separation of South Africa. South Africa was divided into two areas where they were black and white areas. This act had a rule that said the black people can only move out of their lands only if employed as labourers by the whites. The white population was one-fifth of the population and was given 92.5 percent of the land while the rest of the population were blacks and they were restricted to stay on the 7.5 percent of land. In the Eastern Cape, two homelands were created: the Transkei (in 1951) and the Ciskei (in 1961). In 1963 the Transkei became the first homeland to be granted the status of 'self-governing territory within the Republic of South Africa’, with the Ciskei following suit in 1972. The apartheid policies caused economic failure and corruption because very little economic and infrastructural development took place in the homelands. According to the ‘legacy perspective’: the former homelands are historically-determined structural poverty traps. The objective of the study is to describe the extent and change of economic function/role of Ngcobo town and linkages with its surrounding villages. Availability or convenient sampling and random sampling techniques were used to collect primary data from farmers and surrounding villages. Descriptive statistics was used to profile farmers as well as the participants in the surrounding villages. Descriptive statistics was used to describe the change in the economy of Ngcobo town and the change in the economy of the surrounding rural areas. Households in the former homelands devote a large share of their total expenditure to food and beverages, and yet it would appear that a relatively small share of this food originates from these same rural areas. The point of departure of this report is the observation that rural areas are diverse, whereby some areas within the former homeland areas in particular exhibit signs of dynamism which are not understandable in terms of the ‘legacy perspective’.
- Full Text:
- Date Issued: 2018
- Authors: Nikelo, Nqaba Benedictor
- Date: 2018
- Subjects: Homelands (South Africa) Homelands (South Africa) -- Economic conditions
- Language: English
- Type: Thesis , Masters , Agricultural Economics
- Identifier: http://hdl.handle.net/10353/10768 , vital:35757
- Description: In 1913 in South Africa the natives of land act during apartheid resulted to the separation of South Africa. South Africa was divided into two areas where they were black and white areas. This act had a rule that said the black people can only move out of their lands only if employed as labourers by the whites. The white population was one-fifth of the population and was given 92.5 percent of the land while the rest of the population were blacks and they were restricted to stay on the 7.5 percent of land. In the Eastern Cape, two homelands were created: the Transkei (in 1951) and the Ciskei (in 1961). In 1963 the Transkei became the first homeland to be granted the status of 'self-governing territory within the Republic of South Africa’, with the Ciskei following suit in 1972. The apartheid policies caused economic failure and corruption because very little economic and infrastructural development took place in the homelands. According to the ‘legacy perspective’: the former homelands are historically-determined structural poverty traps. The objective of the study is to describe the extent and change of economic function/role of Ngcobo town and linkages with its surrounding villages. Availability or convenient sampling and random sampling techniques were used to collect primary data from farmers and surrounding villages. Descriptive statistics was used to profile farmers as well as the participants in the surrounding villages. Descriptive statistics was used to describe the change in the economy of Ngcobo town and the change in the economy of the surrounding rural areas. Households in the former homelands devote a large share of their total expenditure to food and beverages, and yet it would appear that a relatively small share of this food originates from these same rural areas. The point of departure of this report is the observation that rural areas are diverse, whereby some areas within the former homeland areas in particular exhibit signs of dynamism which are not understandable in terms of the ‘legacy perspective’.
- Full Text:
- Date Issued: 2018
Core self-evaluations, stress and work aspirations of Department of Education officers in selected districts in the Eastern Cape
- Authors: Gabelana, Nomzamo
- Date: 2014
- Language: English
- Type: Thesis , Masters , MCom (Industrial Psychology)
- Identifier: http://hdl.handle.net/10353/944 , vital:26511
- Description: The aim of the study was to investigate the effects of core self-evaluations and stress on the aspiration levels of the Department of Education (DoE) officers. An additional interest was on checking if general relationships amongst the three variables exist and the magnitude of such relationships. A literature study was conducted on three aspects, which are core self-evaluations, stress and work aspirations. This was followed by a survey involving 250 education specialists from four selected districts in the Eastern Cape, which are, Dutywa, Butterworth, Fort Beaufort and Mthatha. Results of the current research indicated that there is a positive relationship between core self-evaluation and DoE stress levels (r=0.32409; p=0.0014). These findings indicate that some individuals have low core self-evaluations due to their exposure to stressful situations hence they negatively appraise themselves and are less confident of themselves. DoE Senior Management Team (SMT) has to strategise and adopt measures that reduce stress levels and encourage positive CSE so as to deal effectively with under-performance.
- Full Text:
- Date Issued: 2014
- Authors: Gabelana, Nomzamo
- Date: 2014
- Language: English
- Type: Thesis , Masters , MCom (Industrial Psychology)
- Identifier: http://hdl.handle.net/10353/944 , vital:26511
- Description: The aim of the study was to investigate the effects of core self-evaluations and stress on the aspiration levels of the Department of Education (DoE) officers. An additional interest was on checking if general relationships amongst the three variables exist and the magnitude of such relationships. A literature study was conducted on three aspects, which are core self-evaluations, stress and work aspirations. This was followed by a survey involving 250 education specialists from four selected districts in the Eastern Cape, which are, Dutywa, Butterworth, Fort Beaufort and Mthatha. Results of the current research indicated that there is a positive relationship between core self-evaluation and DoE stress levels (r=0.32409; p=0.0014). These findings indicate that some individuals have low core self-evaluations due to their exposure to stressful situations hence they negatively appraise themselves and are less confident of themselves. DoE Senior Management Team (SMT) has to strategise and adopt measures that reduce stress levels and encourage positive CSE so as to deal effectively with under-performance.
- Full Text:
- Date Issued: 2014
The Educational Journal
- Date: 1991-02
- Subjects: Education –- South Africa , South Africa -- Politics and government , Government, Resistance to -- South Africa
- Language: English
- Type: text , Article
- Identifier: http://hdl.handle.net/10948/38109 , vital:34401 , Bulk File 7
- Description: The Educational Journal was the official organ of the Teachers' League of South Africa and focussed on education within the context of a racialized South Africa.
- Full Text: false
- Date Issued: 1991-02
- Date: 1991-02
- Subjects: Education –- South Africa , South Africa -- Politics and government , Government, Resistance to -- South Africa
- Language: English
- Type: text , Article
- Identifier: http://hdl.handle.net/10948/38109 , vital:34401 , Bulk File 7
- Description: The Educational Journal was the official organ of the Teachers' League of South Africa and focussed on education within the context of a racialized South Africa.
- Full Text: false
- Date Issued: 1991-02