https://commons.ru.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 Biological activities of plant extracts from Ficus elastica and Selaginella vogelli: an antimalarial, antitrypanosomal and cytotoxity evaluation https://commons.ru.ac.za/vital/access/manager/Repository/vital:35853 Wed 15 May 2024 15:53:09 SAST ]]> Cinnamoyl-Oxaborole Amides: Synthesis and Their in Vitro Biological Activity. https://commons.ru.ac.za/vital/access/manager/Repository/vital:35362 125 μM) was observed. Similarly, these compounds exhibited moderate activity against the human protozoal pathogen Trichomonas vaginalis with no observed effect on common microbiome bacterial species. The cross-species inhibitory activity presents the possibility of these compounds serving as broad-spectrum antibiotics for these prevalent three human pathogens.]]> Tue 07 May 2024 12:34:59 SAST ]]> Synthesis, in vitro cytotoxicity and trypanocidal evaluation of novel 1, 3, 6-substituted non-fluoroquinolones https://commons.ru.ac.za/vital/access/manager/Repository/vital:35409 Tue 07 May 2024 12:33:05 SAST ]]> Synthesis, antiplasmodial and antitrypanosomal evaluation of a series of novel 2-oxoquinoline-based thiosemicarbazone derivatives https://commons.ru.ac.za/vital/access/manager/Repository/vital:35407 50 % was often observed. Except for compound 9o, none of the final compounds exhibited cytotoxic effects against HeLa cells at 20 μM.]]> Tue 07 May 2024 12:31:51 SAST ]]> New thiazolidine-2,4-dione derivatives combined with organometallic ferrocene: Synthesis, structure and antiparasitic activity https://commons.ru.ac.za/vital/access/manager/Repository/vital:35382 90% viability of the HeLa cell line screened.]]> Tue 07 May 2024 12:31:21 SAST ]]> In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants: Antrocaryon klaineanum (Anacardiaceae) and Diospyros conocarpa (Ebenaceae) https://commons.ru.ac.za/vital/access/manager/Repository/vital:35908 Tue 07 May 2024 12:30:54 SAST ]]> Biological activity of plant extracts and isolated compounds from Alchornea laxiflora: Anti-HIV, antibacterial and cytotoxicity evaluation https://commons.ru.ac.za/vital/access/manager/Repository/vital:35907 Tue 07 May 2024 12:30:13 SAST ]]> A New Synthetic Method for Tetraazatricyclic Derivatives and Evaluation of Their Biological Properties https://commons.ru.ac.za/vital/access/manager/Repository/vital:35413 Tue 07 May 2024 12:28:47 SAST ]]> NMR structural elucidation of channaine, an unusual alkaloid from Sceletium tortuosum: https://commons.ru.ac.za/vital/access/manager/Repository/vital:41110 Tue 07 May 2024 11:49:12 SAST ]]> Expanding the SAR of Nontoxic Antiplasmodial Indolyl-3-ethanone Ethers and Thioethers: https://commons.ru.ac.za/vital/access/manager/Repository/vital:41114 Tue 07 May 2024 11:47:49 SAST ]]> Novobiocin–ferrocene conjugates possessing anticancer and antiplasmodial activity independent of HSP90 inhibition. https://commons.ru.ac.za/vital/access/manager/Repository/vital:35359 Tue 07 May 2024 11:27:40 SAST ]]> Identification of Novel Potential Inhibitors of Pteridine Reductase 1 in Trypanosoma brucei via Computational Structure-Based Approaches and in Vitro Inhibition Assays https://commons.ru.ac.za/vital/access/manager/Repository/vital:35647 Tue 07 May 2024 10:34:28 SAST ]]>