https://commons.ru.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 Analysis of macrolide antibiotics https://commons.ru.ac.za/vital/access/manager/Repository/vital:7011 Wed 15 May 2024 15:01:03 SAST ]]> Interactions between steroidal anti-inflammatory agents and collagen https://commons.ru.ac.za/vital/access/manager/Repository/vital:3849 Wed 12 May 2021 16:29:13 SAST ]]> The human skin-blanching assay for in vitro topical corticosteroid assessment. I. Reproducibility of the assay https://commons.ru.ac.za/vital/access/manager/Repository/vital:6381 Tue 14 May 2024 12:39:53 SAST ]]> Comparative blanching activities of proprietary diflucortolone valerate topical preparations https://commons.ru.ac.za/vital/access/manager/Repository/vital:6350 Tue 14 May 2024 10:53:07 SAST ]]> Assessment of some variables affecting the blanching activity of betamethasone 17-valerate cream https://commons.ru.ac.za/vital/access/manager/Repository/vital:6396 Tue 14 May 2024 10:52:37 SAST ]]> The simultaneous determination of trimethoprim, sulphamethoxazole and N4-acetylsulphamethoxazole in biological fluids by high pressure liquid chromatography https://commons.ru.ac.za/vital/access/manager/Repository/vital:6364 Tue 14 May 2024 10:52:15 SAST ]]> The release of betamethasone 17-valerate from extemporaneous dilutions of a proprietary topical cream https://commons.ru.ac.za/vital/access/manager/Repository/vital:6397 Tue 14 May 2024 10:51:53 SAST ]]> Comparative blanching activities of some topical corticosteroid containing lotions https://commons.ru.ac.za/vital/access/manager/Repository/vital:6398 Tue 14 May 2024 10:51:26 SAST ]]> Comparative bioavailability of some locally manufactured betamethasone valerate containing preparations https://commons.ru.ac.za/vital/access/manager/Repository/vital:6399 Tue 14 May 2024 10:50:36 SAST ]]> Assessment of topical corticosteroid preparations: the human skin-blanching assay https://commons.ru.ac.za/vital/access/manager/Repository/vital:6374 Tue 14 May 2024 10:50:13 SAST ]]> Relative potencies of topical corticosteroid formulations https://commons.ru.ac.za/vital/access/manager/Repository/vital:6375 Tue 14 May 2024 10:49:55 SAST ]]> Determination of erythromycin in serum and urine by high performance liquid chromatography with ultraviolet detection https://commons.ru.ac.za/vital/access/manager/Repository/vital:6428 Tue 14 May 2024 10:49:36 SAST ]]> Reply to correspondence: P.M. Gaylarde (1986) The human skin blanching assay—use and abuse https://commons.ru.ac.za/vital/access/manager/Repository/vital:6376 Tue 14 May 2024 10:49:17 SAST ]]> A stability-indicating HPLC assay with on-line clean-up for betamethasone 17-valerate in topical dosage forms https://commons.ru.ac.za/vital/access/manager/Repository/vital:6421 Tue 14 May 2024 10:48:59 SAST ]]> High performance liquid chromatographic analysis of oleandomycin in serum and urine https://commons.ru.ac.za/vital/access/manager/Repository/vital:6429 Tue 14 May 2024 10:48:39 SAST ]]> A stability-indicating liquid chromatographic method for the analysis of erythromycin in stored biological fluids using amperometric detection https://commons.ru.ac.za/vital/access/manager/Repository/vital:6430 Tue 14 May 2024 10:48:10 SAST ]]> Potency ranking of two new topical corticosteroid creams containing 0.1% desonide or 0.05% halometasone utilizing the human skin-blanching assay https://commons.ru.ac.za/vital/access/manager/Repository/vital:6400 Tue 14 May 2024 10:47:47 SAST ]]> Comparison of the blanching activities of Dermovate, Betnovate and Eumovate creams and ointments https://commons.ru.ac.za/vital/access/manager/Repository/vital:6393 Tue 14 May 2024 10:47:18 SAST ]]> Sensitive high-performance liquid chromatographic determination of cyclizine and its demethylated metabolite, norcyclizine, in biological fluids using coulometric detection https://commons.ru.ac.za/vital/access/manager/Repository/vital:6452 Tue 14 May 2024 10:46:51 SAST ]]> Pharmacokinetics of cyclizine following intravenous administration to human volunteers https://commons.ru.ac.za/vital/access/manager/Repository/vital:44214 Tue 14 May 2024 10:46:29 SAST ]]> The human skin blanching assay for in vivo topical corticosteroid assessment. II. Subject- and observer-dependent variation in blanching responses https://commons.ru.ac.za/vital/access/manager/Repository/vital:6382 Tue 14 May 2024 10:45:44 SAST ]]> Evaluation of the proposed FDA pilot-dose response methodology for topical corticosteroid bioequivalence testing https://commons.ru.ac.za/vital/access/manager/Repository/vital:6356 0.95) was noted for both methods of assessment. The chromameter ED[subscript 50] values determined in this study were approximately 2 hours for both preparations. At this dose duration the instrument would not be sensitive enough to distinguish between weak blanching responses and normal skin for bioequivalence assessment purposes.]]> Tue 14 May 2024 10:45:10 SAST ]]> Evaluation of the proposed FDA pilot-dose response methodology for topical corticosteroid bioeqivalence testing [authors' reply in Letters to the Editor] https://commons.ru.ac.za/vital/access/manager/Repository/vital:6423 Tue 14 May 2024 10:44:40 SAST ]]> A capillary zone electrophoresis (CZE) method for the determination of cyclizine hydrochloride in tablets and suppositories https://commons.ru.ac.za/vital/access/manager/Repository/vital:6406 Tue 14 May 2024 10:43:20 SAST ]]> An LC-MS-MS method for the determination of cyclizine in human serum https://commons.ru.ac.za/vital/access/manager/Repository/vital:6408 Tue 14 May 2024 10:42:59 SAST ]]> African herbal medicines in the treatment of HIV: Hypoxis and Sutherlandia: an overview of evidence and pharmacology https://commons.ru.ac.za/vital/access/manager/Repository/vital:6401 Tue 14 May 2024 10:41:28 SAST ]]> Generic substitution: the use of medicinal products containing different salts and implications for safety and efficacy https://commons.ru.ac.za/vital/access/manager/Repository/vital:6445 Tue 14 May 2024 10:41:01 SAST ]]> Bioequivalence assessment of generic products an innovative South African approach https://commons.ru.ac.za/vital/access/manager/Repository/vital:44194 Tue 14 May 2024 10:40:36 SAST ]]> Application of reverse-flow micellar electrokinetic chromatography for the simultaneous determination of flavonols and terpene trilactones in Ginkgo biloba dosage forms https://commons.ru.ac.za/vital/access/manager/Repository/vital:6357 -cyclodextrin concentrations were investigated. A polyimide fused-silica square capillary column (75 μm I.D. × 360 μm O.D.) with a total length of 60.0 cm and effective length of 45.0 cm was used for the separation. The final BGE consisted of 20 mM phosphoric acid, 40 mM SDS and 12 mM -cyclodextrin (pH 2.2) using reverse polarity with a voltage of −17.5 kV. Samples were injected electrokinetically at −5 kV for 3 s for the qualitative analysis and hydrodynamically at 20 mbar for 0.6 s for the quantitative assay. The total run time was 22 min and the limits of detection were 3.13 μg/ml and 1.88 μg/ml for rutin and quercetin, respectively. Fingerprint profiles of the solid oral dosage forms and the results of the quantitative analysis indicated that there were major discrepancies in the marker content between products and illustrates the value of this method for use as a procedure to assess product quality of commercially available Ginkgo biloba products.]]> Tue 14 May 2024 10:40:06 SAST ]]> Sterols and sterolins in Hypoxis hemerocallidea (African potato) https://commons.ru.ac.za/vital/access/manager/Repository/vital:6417 Tue 14 May 2024 10:39:24 SAST ]]> Rapid UPLC - MS/MS method for the determination of ketoprofen in human dermal microdialysis samples https://commons.ru.ac.za/vital/access/manager/Repository/vital:6444 209.00 and 205.00 > 161.00, respectively. Calibration curves were linear over the range 0.5–500 ng/ml with correlation coefficients > 0.999. The accuracy and precision of the method were found to be between 99.97% and 104.67% (R.S.D. < 2%) and the mean recovery of KET from normal saline was 88.03 ± 0.3% (R.S.D. < 2.20%). The LLOQ and LOD values were found to be 0.5 and 0.1 ng/ml respectively whereas the ULOD was set at 500 ng/ml. The method was successfully applied to determine the bioavailability of KET following application of topical KET gel, Fastum® gel, to the skin of human volunteers.]]> Tue 14 May 2024 10:39:01 SAST ]]> Rapid method for the quantitative determination of efavirenz in human plasma https://commons.ru.ac.za/vital/access/manager/Repository/vital:6388 Tue 14 May 2024 10:38:40 SAST ]]> In Vitro Release Testing (IVRT) of Topical Hydrocortisone Acetate Creams: a novel approach using positive and negative controls https://commons.ru.ac.za/vital/access/manager/Repository/vital:38888 Tue 14 May 2024 10:38:22 SAST ]]> In vitro-in vivo evaluation of a sustained release phenylpropanolamine oral dosage form https://commons.ru.ac.za/vital/access/manager/Repository/vital:6360 Tue 14 May 2024 06:44:05 SAST ]]> Phenylpropanolamine hydrochloride https://commons.ru.ac.za/vital/access/manager/Repository/vital:6385 Tue 14 May 2024 06:43:37 SAST ]]> Determination of phenylpropanolamine in serum and urine by high performance liquid chromatography https://commons.ru.ac.za/vital/access/manager/Repository/vital:6361 Tue 14 May 2024 06:43:09 SAST ]]> Pharmacokinetics of phenylpropanolamine in humans after a single dose study https://commons.ru.ac.za/vital/access/manager/Repository/vital:6363 Tue 14 May 2024 06:42:30 SAST ]]>