https://commons.ru.ac.za/vital/access/manager/Index en-us 5 https://commons.ru.ac.za/vital/access/manager/Repository/vital:7011 Wed 15 May 2024 15:01:03 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6381 Tue 14 May 2024 12:39:53 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6396 Tue 14 May 2024 10:52:37 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6364 Tue 14 May 2024 10:52:15 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6374 Tue 14 May 2024 10:50:13 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6428 Tue 14 May 2024 10:49:36 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6429 Tue 14 May 2024 10:48:39 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6452 Tue 14 May 2024 10:46:51 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6382 Tue 14 May 2024 10:45:44 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6423 Tue 14 May 2024 10:44:40 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6445 Tue 14 May 2024 10:41:01 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6357 -cyclodextrin concentrations were investigated. A polyimide fused-silica square capillary column (75 μm I.D. × 360 μm O.D.) with a total length of 60.0 cm and effective length of 45.0 cm was used for the separation. The final BGE consisted of 20 mM phosphoric acid, 40 mM SDS and 12 mM -cyclodextrin (pH 2.2) using reverse polarity with a voltage of −17.5 kV. Samples were injected electrokinetically at −5 kV for 3 s for the qualitative analysis and hydrodynamically at 20 mbar for 0.6 s for the quantitative assay. The total run time was 22 min and the limits of detection were 3.13 μg/ml and 1.88 μg/ml for rutin and quercetin, respectively. Fingerprint profiles of the solid oral dosage forms and the results of the quantitative analysis indicated that there were major discrepancies in the marker content between products and illustrates the value of this method for use as a procedure to assess product quality of commercially available Ginkgo biloba products.]]> Tue 14 May 2024 10:40:06 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6417 Tue 14 May 2024 10:39:24 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:6444 209.00 and 205.00 > 161.00, respectively. Calibration curves were linear over the range 0.5–500 ng/ml with correlation coefficients > 0.999. The accuracy and precision of the method were found to be between 99.97% and 104.67% (R.S.D. < 2%) and the mean recovery of KET from normal saline was 88.03 ± 0.3% (R.S.D. < 2.20%). The LLOQ and LOD values were found to be 0.5 and 0.1 ng/ml respectively whereas the ULOD was set at 500 ng/ml. The method was successfully applied to determine the bioavailability of KET following application of topical KET gel, Fastum® gel, to the skin of human volunteers.]]> Tue 14 May 2024 10:39:01 SAST ]]>