https://commons.ru.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 https://commons.ru.ac.za/vital/access/manager/Repository/vital:3311 Wed 12 May 2021 23:47:17 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:4044 Wed 12 May 2021 23:36:48 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:5866 Wed 12 May 2021 23:25:35 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:4392 Wed 12 May 2021 20:24:11 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:2809 Wed 12 May 2021 19:15:27 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:3866 Wed 12 May 2021 16:33:12 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:5234 0.05) between slopes of the control and 0.11 ± 0.02 mg/l Cu, and between 0.29 ± 0.02 and 47 ± 0.04 mg/l Cu before and after introducing food in the tanks. The slopes of both the control and 0.11 ± 0.02 mg/l Cu were significantly different from those of 0.29 ± 0.02 and 0.47 ± 0.04 mg/l Cu (p < 0.05). There were significant differences in the mean opercular movements per minute between treatments (p < 0.05). There was hyperventilation at 0.11 ± 0.02 mg/l Cu i.e. 87 ± 18 opercular movements per minute (mean ± standard deviation) and hypoventilation at 0.29 ± 0.02 and 0.47 ± 0.04 mg/l Cu i.e. 37 ± 34 and 13 ± 6 opercular movements per minute compared to the control. Hypo- and hyperventilation were related to the lesser and greater gill damage, respectively. In conclusion Cu accumulation and effects on histology of the liver, gills and were related to the concentration of Cu in the water and duration of exposure showing a gradual increase in incidence and intensity with larger duration of exposure time and increasing Cu concentration. The fish were initially able to homeostatically regulate and detoxify Cu. However, as the exposure continued, the homeostatic mechanism appears to have failed to cope with the increasing metal burden causing advanced histological changes.]]> Wed 12 May 2021 15:54:00 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:5378 Thu 13 May 2021 04:05:17 SAST ]]> https://commons.ru.ac.za/vital/access/manager/Repository/vital:5662 Thu 13 May 2021 03:15:18 SAST ]]>