https://commons.ru.ac.za/vital/access/manager/Index en-us 5 Drug transport mechanisms from carbopol/eudragit verapamil sustained-release tablets https://commons.ru.ac.za/vital/access/manager/Repository/vital:44273 Tue 14 May 2024 11:03:40 SAST ]]> Development and assessment of a USP Apparatus 3 dissolution test method for sustained-release Nevirapine matrix tablets https://commons.ru.ac.za/vital/access/manager/Repository/vital:44271 80% NVP was released from the tablets over the test period. The NVP release rate increased with an increase in the mesh pore size; however, the extent of release was not affected by this parameter. Dissolution test samples were analyzed using HPLC, and dissolution methods were validated for NVP stability in the dissolution medium, specificity, linearity and range, repeatability, intermediate precision, and accuracy as defined by ICH. The dissolution method used for testing NVP tablets can be regarded as an appropriate tool for the evaluation of sustained-release (SR) NVP formulations and the impact of formulation composition and product quality attributes on drug release.]]> Tue 14 May 2024 11:01:21 SAST ]]>