https://commons.ru.ac.za/vital/access/manager/Index en-us 5 Analysis of the anti-cancer activity of novel indigenous algal compounds in breast cancer: towards the development of a model for screening anti-cancer stem cell activity https://commons.ru.ac.za/vital/access/manager/Repository/vital:3925 Wed 12 May 2021 23:30:20 SAST ]]> Molecular chaperone expression and function in breast cancer and breast cancer stem cells https://commons.ru.ac.za/vital/access/manager/Repository/vital:4141 Wed 12 May 2021 23:28:19 SAST ]]> The role of Hsp90/Hsp70 organising protein (Hop) in the Proliferation, Survival and Migration of Breast Cancer Cells. https://commons.ru.ac.za/vital/access/manager/Repository/vital:4130 Wed 12 May 2021 18:19:45 SAST ]]> Progestin receptor heterogeneity in a breast cancer cell line https://commons.ru.ac.za/vital/access/manager/Repository/vital:4039 Wed 12 May 2021 16:27:32 SAST ]]> The physical activity levels and preferences of South African breast cancer survivors : a pilot study https://commons.ru.ac.za/vital/access/manager/Repository/vital:42855 0.05, R2 = 0.95) between moderate-intensity physical activity and total physical activity levels. High levels of weekly sedentary behaviour and sitting time (302.60 ± 169.96 minutes) were reported. A weak, non-significant, positive correlation was found between total sedentary time and BMI (p>0.05, R2 = 0.1). A weak, non-significant, negative correlation was found between age and sedentary time (p>0.05, R2 = 0.002). More participants below 50 years were insufficiently active compared to above the age of 50 years. 1.7 to 2.6 years since diagnosis saw the greatest number of insufficiently active survivors and the category over 2.6 years since diagnosis saw the most active survivors. Most breast cancer survivors (71.10% & 82.05%) indicated being interested in and feeling capable of participating in an exercise programme (p>0.05, R2 = 0.72). The favoured preference for receiving physical activity advice was face-to-face with an exercise specialist at a cancer centre before treatment. Participation preferences included starting a programme immediately after treatment, in a home-based setting with one or two other people, where walking and a moderate exercise intensity were the preferred exercise type and level of intensity. Data collection occurred both immediately prior to (42% of participants) and during (56% of participants) the South African Covid-19 lockdown, so the results should be seen in light of this context. Conclusion: The current study is one of the first to explore physical activity rates and preferences of South African breast cancer survivors. As a group and individually these survivors were meeting public physical activity guidelines and engaging in the recommended weekly minutes. The high sitting time coupled with the high overweight and obesity levels highlight the need for positive behavioural changes including improved levels of physical activity and reduced sedentary behaviour. These changes need involvement from the numerous levels of society that affect health. Broad physical activity guidelines need to be developed not only to improve physical activity levels in breast cancer survivors but to work as a preventative measure by facilitating physical activity promotion in the general population. The findings of this study demonstrate that this group of South African breast cancer survivors is open to physical activity advice, to programmes and to improving physical activity levels.]]> Wed 12 May 2021 15:00:22 SAST ]]> Analysis of the interaction of Hsp90 with the extracellular matrix protein fibronectin (FN) https://commons.ru.ac.za/vital/access/manager/Repository/vital:4170 Thu 13 May 2021 03:15:16 SAST ]]>