https://commons.ru.ac.za/vital/access/manager/Index ${session.getAttribute("locale")} 5 Synthesis, photophysicochemical properties and photodynamic therapy activities of indium and zinc phthalocyanines when incorporated into Pluronic polymer micelles https://commons.ru.ac.za/vital/access/manager/Repository/vital:41489 50% cell viability) at concentrations ≤100 μg/mL, however the conjugates showed < 45% cell viability at concentrations ≤ 100 μg/mL, probably due to the small micellar size and EPR effect. The findings from this work show the importance of incorporating photosensitizers such as phthalocyanines into Pluronic polymers micelles and making them water soluble and ultimately improving their photodynamic effect.]]> Wed 12 May 2021 14:58:28 SAST ]]> In vitro susceptibility of Staphylococcus aureus to porphyrin-silver mediated photodynamic antimicrobial chemotherapy https://commons.ru.ac.za/vital/access/manager/Repository/vital:41484 Wed 12 May 2021 14:28:57 SAST ]]> Azadipyrromethenes for applications in photodynamic antimicrobial chemotherapy, photodynamic therapy and optical limiting https://commons.ru.ac.za/vital/access/manager/Repository/vital:41333 Wed 12 May 2021 13:45:15 SAST ]]> Photo-physicochemical characterization and in vitro Photodynamic Therapy Activity of Phthalocyanine-Graphene Quantum Dots Conjugates https://commons.ru.ac.za/vital/access/manager/Repository/vital:37891 Thu 13 May 2021 05:55:46 SAST ]]> The construction of phthalocyanine- carbon nanoparticle conjugates for applications in photodynamic therapy and non-linear optics https://commons.ru.ac.za/vital/access/manager/Repository/vital:44750 22% cell viability at concentrations ≤ 50 μg/mL relative to conjugates with <22% cell viability at concentrations ≤ 50 μg/mL. There was no direct relationship between PDT and singlet oxygen quantum yields. Nonlinear optical characteristics of complexes was improved upon conjugation of DNDs. Absorbance, input energy, percentage loading, central metal, substituent of Pc and nature of interaction (covalent, noncovalent) are amongst some of the factors that influence nonlinear absorption properties of materials used in this study. All materials followed reverse saturable absorption through two photon absorption mechanism at the excitation wavelength of 532 nm. Aggregates reduce excited state lifetime and Beff under high concentrations/absorbance. A direct relationship between absorbance and Beff of DNDs nanoconjugated systems at low concentrations result in increased optical limiting characteristics of materials. The findings from this work show the importance of linking (nonlinear optics and photodynamic therapy) and doping (photodynamic therapy) photosensitisers such as phthalocyanines and sometimes boron dipyrromethenes onto carbon based nanoparticles for the enhanced characteristics in variable applications.]]> Mon 15 Nov 2021 16:13:10 SAST ]]> The synthesis and characterisation of Sn(IV) porphyrin derivatives and their potential application in anti-cancer and antimicrobial photodynamic therapy https://commons.ru.ac.za/vital/access/manager/Repository/vital:44791 Fri 22 Oct 2021 15:54:57 SAST ]]>