${session.getAttribute("locale")} 5 Biochemical evaluation of Tulbaghia violacea harv.rhizomes in diet induced hypercholestrolemic rats Wed 12 May 2021 19:48:08 SAST ]]> Efficacy of two medical plant extracts and metformin in the prevention of diet induced fatty liver 5% per liver weight in all treated groups. The present study demonstrates that these two plant extracts and metformin have different glucogenic and lipogenic effects from that presented by HFD alone when compared to the LFD alone. In conclusion, metformin and P. africana extract can attenuate HFD‐induced fatty liver without changing the dietary habits. Hence S. frutescens extract is less effective in the prevention of HFD‐induced fatty liver. A change in the dietary habits is recommended to be considered during the use of these three remedies in the treatment of HFD‐induced insulin resistance and fatty liver. All three treatments enhanced antioxidant capacity, and may improve insulin resistance and fatty liver mediated by the present HFD through different mechanism of actions in the liver.]]> Wed 12 May 2021 19:40:44 SAST ]]> African traditional medicine-antiretroviral interactions : effects of Sutherlandia frutescens on the pharmacokinetics of Atazanavir Wed 12 May 2021 19:39:20 SAST ]]> Chang liver cell line as a model for Type II Diabetes in the liver and possible reversal of this condition by an indigenous medicinal plant Thu 13 May 2021 07:36:07 SAST ]]> Assessment of the anti-Listerial properties of Garcinia kola (Heckel) seeds 10 mg/ml for the aqueous extract. The minimum bactericidal concentration (MBC) ranges of the extracts were 0.625–10 mg/ml for both the n-hexane and the dichloromethane extract; 5-10 mg/ml for the methanol extract; and those for the aqueous extract were above 10 mg/ml against all the susceptible Listeria isolates. The rate of kill analysis was then determined for the three most active crude extracts that is excluding the aqueous extract and it was assessed against four representative Listeria species namely L. monocytogenes (LAL 8), L. grayi (LAL 15), L. ivanovii (LEL 30) and L. ivanovii (LEL 18). All the three extracts showed a general trend of being concentration and time dependent in their rate of kill profiles such that most bacteria cells were killed at the highest test concentration of 4× MIC value after the maximum exposure time of 2 h. The n-hexane, dichloromethane and methanol extracts were bactericidal against 4, 3 and 1 isolates out of the four test Listeria isolates respectively.]]> Thu 13 May 2021 06:09:04 SAST ]]> The antifungal activity of an aqueous Tulbaghia violacea plant extract against Aspergillus flavus Thu 13 May 2021 05:30:49 SAST ]]> Pharmaceutical analysis and drug interaction studies : African potato (Hypoxis hemerocallidea) Thu 13 May 2021 05:01:26 SAST ]]> The in vitro biological activities of three Hypoxis species and their active compounds Thu 13 May 2021 03:37:18 SAST ]]> Chemical transformations and phytochemical studies of bioactive components from extracts of Rosmarinus officinalis L Thu 13 May 2021 01:11:51 SAST ]]>