https://commons.ru.ac.za/vital/access/manager/Index en-us 5 Un-functionalized gold nanoparticles as a simple colorimetric probe for sensitive and selective detection of dopamine https://commons.ru.ac.za/vital/access/manager/Repository/vital:45522 Tue 07 May 2024 15:44:29 SAST ]]> Purification and biochemical characterisation of a putative sodium channel agonist secreted from the South African Knobbly sea anemone Bunodosoma capense https://commons.ru.ac.za/vital/access/manager/Repository/vital:45421 Tue 07 May 2024 15:44:03 SAST ]]> Phytochemical, anti-inflammatory and anti-trypanosomal properties of Anthocleista vogelii Planch (Loganiaceae) stem bark https://commons.ru.ac.za/vital/access/manager/Repository/vital:45419 5000 mg/kg. The n-hexane fraction of the extract contains steroids, terpenes and fatty acids and yielded non-cytotoxic terpenoidal column fraction with anti-trypanosomal IC50 of 3.0 μg/mL. The ethylacetate fraction at 100 mg/kg dose significantly (p less than 0.05) provoked 37.8, 62.5 and 69.7% inhibition of oedema induced by egg-albumin at the second, fourth and sixth hours respectively. Conclusion: The study demonstrated that the anti-inflammatory and anti-trypanosomal activities of A. vogelii are probably due to non-cytotoxic terpenoids and validated the traditional use of A. vogelii in the treatment of inflammation and sleeping sickness.]]> Tue 07 May 2024 15:43:34 SAST ]]> Nano-enabled liposomal mucoadhesive films for enhanced efavirenz buccal drug delivery https://commons.ru.ac.za/vital/access/manager/Repository/vital:45417 Tue 07 May 2024 15:43:11 SAST ]]> Molecular Networking Reveals Two Distinct Chemotypes in Pyrroloiminoquinone-Producing Tsitsikamma favus Sponges https://commons.ru.ac.za/vital/access/manager/Repository/vital:36673 Tue 07 May 2024 15:42:45 SAST ]]> Green synthesis of zinc oxide nanoparticles using Solanum torvum (L) leaf extract and evaluation of the toxicological profile of the ZnO nanoparticles–hydrogel composite in Wistar albino rats https://commons.ru.ac.za/vital/access/manager/Repository/vital:45416 Tue 07 May 2024 15:42:16 SAST ]]> Encapsulation of isoniazid-conjugated phthalocyanine-In-cyclodextrin-in-liposomes using heating method https://commons.ru.ac.za/vital/access/manager/Repository/vital:45414 Tue 07 May 2024 15:41:56 SAST ]]> Cordidepsine is A Potential New Anti-HIV Depsidone from Cordia millenii https://commons.ru.ac.za/vital/access/manager/Repository/vital:45413 Tue 07 May 2024 15:41:33 SAST ]]> Co-encapsulation of rifampicin and isoniazid in crude soybean lecithin liposomes https://commons.ru.ac.za/vital/access/manager/Repository/vital:44005 Tue 07 May 2024 15:41:08 SAST ]]> In vitro antimalarial, antitrypanosomal and HIV-1 integrase inhibitory activities of two Cameroonian medicinal plants https://commons.ru.ac.za/vital/access/manager/Repository/vital:45519 Tue 07 May 2024 12:28:00 SAST ]]> Antiplasmodial Activity of the n-Hexane Extract from Pleurotus ostreatus (Jacq. ex. Fr) P. Kumm https://commons.ru.ac.za/vital/access/manager/Repository/vital:45516 n-hexane extract (IC50=25.18 μg/mL). It also showed mild cytotoxicity (IC50>100 μg/mL; selectivity index >4) compared to the reference drug emetine (IC50=0.013 μg/mL). The known sterol, ergostan-5,7,22-trien-3-ol, was isolated and characterized from the extract. Conclusion: This study reporting for the first time the antiplasmodial activity of P. ostreatus revealed its nutraceutical potential in the management of malaria.]]> Tue 07 May 2024 12:27:04 SAST ]]> Anti-HIV-1 integrase potency of methylgallate from Alchornea cordifolia using in vitro and in silico approaches: https://commons.ru.ac.za/vital/access/manager/Repository/vital:41001 Tue 07 May 2024 10:31:36 SAST ]]>