https://commons.ru.ac.za/vital/access/manager/Index en-us 5 Development, manufacture and characterization of niosomes for the delivery for nevirapine https://commons.ru.ac.za/vital/access/manager/Repository/vital:44002 Tue 14 May 2024 11:51:22 SAST ]]> Development and Validation of a Stability-indicating RP-HPLC Method Using Quality by Design for Estimating Captopril https://commons.ru.ac.za/vital/access/manager/Repository/vital:44003 2) for captopril and the internal standard with retention times of 3.1 and 6.2 min, respectively. The experimental data revealed that acetonitrile content in the mobile phase and pH are significant factors that affect the retention time and resolution of captopril. Normal probability plots revealed that the residual and predicted data fall approximately on a straight line, indicating that the experimental error for these studies was evenly distributed suggesting that the model could be used to navigate the design space. This approach is useful to expedite method development and optimization activities in analytical laboratories.]]> Tue 14 May 2024 11:50:59 SAST ]]> Application of quality by design principles for optimizing process variables of Extrusion and Spheronization of a Captopril Pellet Formulation: https://commons.ru.ac.za/vital/access/manager/Repository/vital:40098 Tue 14 May 2024 11:47:44 SAST ]]> Short term stability testing of efavirenz-loaded solid lipid nanoparticle (SLN) and nanostructured lipid carrier (NLC) dispersions https://commons.ru.ac.za/vital/access/manager/Repository/vital:44000 90%. The optimized nanocarriers exhibited biphasic in vitro release patterns with an initial burst release during the initial 0–3 h followed by sustained release over a 24 h period The colloidal systems showed excellent stability in terms of Zeta potential, particle size, polydispersity index and encapsulation efficiency when stored for 8 weeks at 25 °C/60% RH in comparison to when stored at 40 °C/75% RH. The formulations manufactured using the optimized conditions and composition proved to be physically stable as aqueous dispersions.]]> Tue 14 May 2024 11:14:37 SAST ]]> Stability indicating HPLC-ECD method for the analysis of clarithromycin in pharmaceutical dosage forms: Method scaling versus re-validation. https://commons.ru.ac.za/vital/access/manager/Repository/vital:43984 Tue 14 May 2024 10:58:54 SAST ]]> Design, evaluation and optimization of taste masked clarithromycin powder https://commons.ru.ac.za/vital/access/manager/Repository/vital:44001 Tue 14 May 2024 10:58:36 SAST ]]> An artificial neural network approach to predict the effects of formulation and process variables on prednisone release from a multipartite system https://commons.ru.ac.za/vital/access/manager/Repository/vital:43933 Tue 14 May 2024 10:58:09 SAST ]]> Co-encapsulation of rifampicin and isoniazid in crude soybean lecithin liposomes https://commons.ru.ac.za/vital/access/manager/Repository/vital:44005 Tue 07 May 2024 15:41:08 SAST ]]>